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Wyszukujesz frazę ""Reactive oxygen species"" wg kryterium: Temat


Tytuł :
GPR120 Inhibits RANKL-Induced Osteoclast Formation and Resorption by Attenuating Reactive Oxygen Species Production in RAW264.7 Murine Macrophages.
Autorzy :
Sithole C; Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.
Pieterse C; Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.
Howard K; Division of Clinical Pharmacology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town 8000, South Africa.
Kasonga A; Department of Physiology, Faculty of Health Sciences, University of Pretoria, Pretoria 0001, South Africa.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 29; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 29.
Typ publikacji :
Journal Article
MeSH Terms :
Biphenyl Compounds/*pharmacology
Bone Resorption/*prevention & control
Macrophages/*drug effects
Osteoclasts/*drug effects
Phenylpropionates/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Receptors, G-Protein-Coupled/*agonists
Animals ; Bone Resorption/chemically induced ; Bone Resorption/metabolism ; Heme Oxygenase-1/metabolism ; Macrophages/cytology ; Macrophages/metabolism ; Membrane Proteins/metabolism ; Mice ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; NF-E2-Related Factor 2/metabolism ; Osteoclasts/cytology ; Osteoclasts/metabolism ; RANK Ligand ; RAW 264.7 Cells ; RNA Interference ; Reactive Oxygen Species/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Curcumin induced G2/M cycle arrest in SK-N-SH neuroblastoma cells through the ROS-mediated p53 signaling pathway.
Autorzy :
Ye Z; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Chen D; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zheng R; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Chen H; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Xu T; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Wang C; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zhu S; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Gao X; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Zhang J; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Li D; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Pang Y; Department of Biology, New York University, New York, NY, USA.
Zhu B; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Li Y; Center Laboratory, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.; Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications, Jinan University, Guangzhou, China.
Jia W; Department of Pediatric Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
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Źródło :
Journal of food biochemistry [J Food Biochem] 2021 Sep; Vol. 45 (9), pp. e13888. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Curcumin*/pharmacology
Neuroblastoma*/drug therapy
Reactive Oxygen Species*/metabolism
Tumor Suppressor Protein p53*/genetics
Tumor Suppressor Protein p53*/metabolism
Cell Line, Tumor ; Humans ; Signal Transduction
Czasopismo naukowe
Tytuł :
Interplay between reactive oxygen and nitrogen species in living organisms.
Autorzy :
Lushchak VI; Department of Biochemistry and Biotechnology, Vasyl Stefanyk Precarpathian National University, 57 Shevchenko Str., Ivano-Frankivsk, 76018, Ukraine; I. Horbachevsky Ternopil National Medical University, 1 m. Voli, Ternopil, 46002, Ukraine; Research and Development University, 13a Shota Rustaveli Str., Ivano-Frankivsk, 76000, Ukraine. Electronic address: .
Lushchak O; Department of Biochemistry and Biotechnology, Vasyl Stefanyk Precarpathian National University, 57 Shevchenko Str., Ivano-Frankivsk, 76018, Ukraine; Research and Development University, 13a Shota Rustaveli Str., Ivano-Frankivsk, 76000, Ukraine. Electronic address: .
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Nov 01; Vol. 349, pp. 109680. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Reactive Nitrogen Species/*metabolism
Reactive Oxygen Species/*metabolism
Animals ; Arginine/chemistry ; Arginine/metabolism ; Cysteine/chemistry ; Cysteine/metabolism ; Nitric Oxide Synthase/metabolism ; Oxidation-Reduction ; Oxidoreductases/metabolism ; Plants/chemistry ; Plants/metabolism ; Reactive Nitrogen Species/chemistry ; Reactive Oxygen Species/chemistry
Czasopismo naukowe
Tytuł :
AZD8055 ameliorates experimental autoimmune encephalomyelitis via the mTOR/ROS/NLRP3 pathway.
Autorzy :
He M; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Wu DM; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Zhao YY; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Yu Y; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Deng SH; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Liu T; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Zhang T; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Li J; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China.
Wang F; Clinical Laboratory, Xindu District People's Hospital of Chengdu, PR China. Electronic address: .
Xu Y; School of Clinical Medicine, Chengdu Medical College, The First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610500, PR China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Oct 08; Vol. 573, pp. 27-34. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Encephalomyelitis, Autoimmune, Experimental/*drug therapy
Morpholines/*pharmacology
NLR Family, Pyrin Domain-Containing 3 Protein/*antagonists & inhibitors
Reactive Oxygen Species/*antagonists & inhibitors
TOR Serine-Threonine Kinases/*antagonists & inhibitors
Animals ; Encephalomyelitis, Autoimmune, Experimental/metabolism ; Female ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pyroptosis/drug effects ; Reactive Oxygen Species/metabolism ; TOR Serine-Threonine Kinases/metabolism
Czasopismo naukowe
Tytuł :
Bifunctional chiral selenium-containing 1,4-diarylazetidin-2-ones with potent antitumor activities by disrupting tubulin polymerization and inducing reactive oxygen species production.
Autorzy :
Tang H; School of Pharmacy, Fudan University, Shanghai, 201203, China.
Liang Y; School of Pharmacy, Fudan University, Shanghai, 201203, China; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China.
Cheng J; School of Pharmacy, Fudan University, Shanghai, 201203, China.
Ding K; State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, 200032, China. Electronic address: .
Wang Y; School of Pharmacy, Fudan University, Shanghai, 201203, China; Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Shanghai Jiao Tong University, Shanghai, 200240, China. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113531. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Azetidines/*pharmacology
Organoselenium Compounds/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Tubulin/*metabolism
Tubulin Modulators/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Azetidines/chemistry ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Organoselenium Compounds/chemical synthesis ; Organoselenium Compounds/chemistry ; Polymerization/drug effects ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; Tubulin Modulators/chemical synthesis ; Tubulin Modulators/chemistry
Czasopismo naukowe
Tytuł :
Serum Albumin: A Multifaced Enzyme.
Autorzy :
De Simone G; Dipartimento di Scienze, Università degli Studi Roma Tre, Viale Marconi 446, 00146 Roma, Italy.
di Masi A; Dipartimento di Scienze, Università degli Studi Roma Tre, Viale Marconi 446, 00146 Roma, Italy.
Ascenzi P; Laboratorio Interdipartimentale di Microscopia Elettronica, Università degli Studi Roma Tre, Via della Vasca Navale 79, 00146 Roma, Italy.; Accademia Nazionale dei Lincei, Via della Lungara 10, 00165 Roma, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 18; Vol. 22 (18). Date of Electronic Publication: 2021 Sep 18.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Green Chemistry Technology*
Reactive Oxygen Species*
Serum Albumin, Human/*chemistry
Animals ; Antioxidants/chemistry ; Aspirin/chemistry ; Biomarkers ; Catalysis ; Fructose-Bisphosphate Aldolase/metabolism ; Glucuronidase/chemistry ; Heme/chemistry ; Humans ; Ions ; Ligands ; Lipid Peroxidation ; Molecular Conformation ; Phosphopyruvate Hydratase/chemistry ; Protein Binding ; Rats
Czasopismo naukowe
Tytuł :
Scavenging reactive oxygen species is a potential strategy to protect Larimichthys crocea against environmental hypoxia by mitigating oxidative stress.
Autorzy :
Luo SY; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Liu C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Ding J; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Gao XM; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Wang JQ; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Zhang YB; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Du C; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Hou CC; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China.
Zhu JQ; Key Laboratory of Applied Marine Biotechnology by the Ministry of Education, School of Marine Sciences, Ningbo University, Ningbo, Zhejiang 315211, China. E-mail:.
Lou B; Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang 310021, China. E-mail:.
Wu XF; State Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
Shen WL; State Key Laboratory of Large Yellow Croaker Breeding, Ningbo Academy of Oceanology and Fishery, Ningbo, Zhejiang 315012, China.
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Źródło :
Zoological research [Zool Res] 2021 Sep 18; Vol. 42 (5), pp. 592-605.
Typ publikacji :
Journal Article
MeSH Terms :
Reactive Oxygen Species*
Antioxidants/*metabolism
Fishes/*metabolism
Oxidative Stress/*physiology
Oxygen/*chemistry
Oxygen/*metabolism
Animals ; Cell Line ; Cell Survival ; Environment ; Homeostasis ; NADP
Czasopismo naukowe
Tytuł :
Gene interfered-ferroptosis therapy for cancers.
Autorzy :
Gao J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Luo T; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China.
Wang J; State Key Laboratory of Bioelectronics, Southeast University, Nanjing, China. .
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Źródło :
Nature communications [Nat Commun] 2021 Sep 07; Vol. 12 (1), pp. 5311. Date of Electronic Publication: 2021 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
RNA Interference*
Cation Transport Proteins/*antagonists & inhibitors
Ferroptosis/*genetics
Iron/*metabolism
Lipocalin-2/*antagonists & inhibitors
Neoplasms/*therapy
Reactive Oxygen Species/*agonists
Animals ; CRISPR-Associated Proteins/genetics ; CRISPR-Associated Proteins/metabolism ; Cation Transport Proteins/genetics ; Cation Transport Proteins/metabolism ; Cell Line, Tumor ; Dependovirus/genetics ; Dependovirus/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Lipocalin-2/genetics ; Lipocalin-2/metabolism ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; MicroRNAs/genetics ; MicroRNAs/metabolism ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Nanoparticles/administration & dosage ; Nanoparticles/chemistry ; Neoplasms/genetics ; Neoplasms/mortality ; Neoplasms/pathology ; Promoter Regions, Genetic ; Reactive Oxygen Species/metabolism ; Signal Transduction ; Spleen/metabolism ; Spleen/pathology ; Survival Analysis ; Tumor Burden ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Antrocaryon amazonicum: An unexploited Amazonian fruit with high potential of scavenging reactive oxygen and nitrogen species.
Autorzy :
Pereira Barbosa-Carvalho AP; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Texeira Costa Leitão DDS; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Campos de Siqueira F; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
Zerlotti Mercadante A; Department of Food Science and Nutrition, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil.
Campos Chisté R; Postgraduate Program of Food Science and Technology, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.; Faculty of Food Engineering, Institute of Technology, Federal University of Pará (UFPA), Belém, Pará, Brazil.
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Źródło :
Journal of food science [J Food Sci] 2021 Sep; Vol. 86 (9), pp. 4045-4059. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article
MeSH Terms :
Anacardiaceae*/chemistry
Fruit*/chemistry
Reactive Nitrogen Species*/chemistry
Reactive Oxygen Species*/chemistry
Antioxidants/chemistry ; Brazil ; Plant Extracts/chemistry
Czasopismo naukowe
Tytuł :
Helicobacter pylori induced reactive oxygen Species: A new and developing platform for detection.
Autorzy :
Jain U; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
Saxena K; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
Chauhan N; Amity Institute of Nanotechnology (AINT), Amity University Uttar Pradesh, Noida, India.
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Źródło :
Helicobacter [Helicobacter] 2021 Jun; Vol. 26 (3), pp. e12796. Date of Electronic Publication: 2021 Mar 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Helicobacter Infections*/diagnosis
Helicobacter Infections*/metabolism
Oxidative Stress*
Reactive Oxygen Species*/analysis
Reactive Oxygen Species*/metabolism
Gastric Mucosa/metabolism ; Gastric Mucosa/microbiology ; Helicobacter pylori ; Humans ; Stomach Neoplasms/metabolism ; Stomach Neoplasms/microbiology
Czasopismo naukowe
Tytuł :
DHA ameliorates MeHg‑induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway.
Autorzy :
Zhang H; Ministry of Education‑Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, P.R. China.
Wang S; School of Public Health, Shanghai Jiao Tong University, Shanghai 200025, P.R. China.
Wang Y; School of Public Health, Shanghai Jiao Tong University, Shanghai 200025, P.R. China.
Lu A; Ministry of Education‑Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, P.R. China.
Hu C; School of Public Health, Shanghai Jiao Tong University, Shanghai 200025, P.R. China.
Yan C; Ministry of Education‑Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, P.R. China.
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Źródło :
Molecular medicine reports [Mol Med Rep] 2021 Aug; Vol. 24 (2). Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Docosahexaenoic Acids/*pharmacology
MAP Kinase Signaling System/*drug effects
Methylmercury Compounds/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Acetylcysteine/pharmacology ; Animals ; Apoptosis/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; JNK Mitogen-Activated Protein Kinases/metabolism ; PC12 Cells ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Rats ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Nitazoxanide impairs mitophagy flux through ROS-mediated mitophagy initiation and lysosomal dysfunction in bladder cancer.
Autorzy :
Sun H; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Ou T; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China; Medical Laboratory, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China.
Hu J; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong 999077, China.
Yang Z; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Lei Q; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Li Y; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Wang G; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Li Y; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Wu K; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Wang S; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China.
Wu S; Institute of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen 518000, China; Shenzhen Following Precision Medical Research Institute, Luohu Hospital Group, Shenzhen 518000, China; Teaching Center of Shenzhen Luohu Hospital, Shantou University Medical College, Shenzhen 518000, China; Department of Urology and Guangdong Key Laboratory of Urology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510000, China. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Aug; Vol. 190, pp. 114588. Date of Electronic Publication: 2021 May 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Lysosomes/*metabolism
Mitophagy/*drug effects
Nitro Compounds/*pharmacology
Reactive Oxygen Species/*metabolism
Thiazoles/*pharmacology
Urinary Bladder Neoplasms/*metabolism
Animals ; Antineoplastic Agents/therapeutic use ; Antiparasitic Agents/pharmacology ; Antiparasitic Agents/therapeutic use ; Dose-Response Relationship, Drug ; Female ; HEK293 Cells ; Humans ; Lysosomes/drug effects ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Mitophagy/physiology ; Nitro Compounds/therapeutic use ; Reactive Oxygen Species/antagonists & inhibitors ; Thiazoles/therapeutic use ; Urinary Bladder Neoplasms/drug therapy
Czasopismo naukowe
Tytuł :
CD36 Signal Transduction in Metabolic Diseases: Novel Insights and Therapeutic Targeting.
Autorzy :
Karunakaran U; Innovative Center for Aging Research, Yeungnam University Medical Center, Daegu 42415, Korea.
Elumalai S; Innovative Center for Aging Research, Yeungnam University Medical Center, Daegu 42415, Korea.
Moon JS; Innovative Center for Aging Research, Yeungnam University Medical Center, Daegu 42415, Korea.; Yeungnam University College of Medicine, Daegu 42415, Korea.
Won KC; Innovative Center for Aging Research, Yeungnam University Medical Center, Daegu 42415, Korea.; Yeungnam University College of Medicine, Daegu 42415, Korea.
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Źródło :
Cells [Cells] 2021 Jul 20; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
CD36 Antigens/*metabolism
Diabetes Mellitus/*metabolism
Hyperglycemia/*metabolism
Insulin-Secreting Cells/*metabolism
Reactive Oxygen Species/*metabolism
Signal Transduction/*genetics
Amyloid/metabolism ; Anti-Inflammatory Agents/therapeutic use ; CD36 Antigens/antagonists & inhibitors ; CD36 Antigens/genetics ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/genetics ; Diabetes Mellitus/pathology ; Fatty Acids/metabolism ; Gene Expression Regulation ; Humans ; Hyperglycemia/drug therapy ; Hyperglycemia/genetics ; Hyperglycemia/pathology ; Inflammation ; Insulin/metabolism ; Insulin Receptor Substrate Proteins/genetics ; Insulin Receptor Substrate Proteins/metabolism ; Insulin Resistance ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/pathology ; Lipoproteins, LDL/metabolism ; Molecular Targeted Therapy ; NF-kappa B/genetics ; NF-kappa B/metabolism ; Reactive Oxygen Species/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Electrochemical Measurements Reveal Reactive Oxygen Species in Stress Granules*.
Autorzy :
Hu K; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
Relton E; Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Locker N; Faculty of Health and Medical Sciences, School of Biosciences and Medicine, University of Surrey, Guildford, Surrey, GU2 7XH, UK.
Phan NTN; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
Ewing AG; Department of Chemistry and Molecular Biology, University of Gothenburg, Kemivägen 10, 41296, Gothenburg, Sweden.
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Źródło :
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2021 Jul 05; Vol. 60 (28), pp. 15302-15306. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Electrochemical Techniques*
Neoplasms/*diagnosis
Reactive Oxygen Species/*analysis
Humans ; Neoplasms/metabolism ; Neurodegenerative Diseases/diagnosis ; Neurodegenerative Diseases/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Virus Diseases/diagnosis ; Virus Diseases/metabolism
Czasopismo naukowe
Tytuł :
Effects of Superoxide Dismutase Inhibitors and Glucose on Cell Death and Generation of Reactive Oxygen Species in Pea Leaves.
Autorzy :
Samuilov VD; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .
Kiselevsky DB; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia. .
Dzyubinskaya EV; Faculty of Biology, Lomonosov Moscow State University, Moscow, 119234, Russia.
Frolova OY; Institute of Mitoengineering, Lomonosov Moscow State University, Moscow, 119234, Russia.
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Źródło :
Biochemistry. Biokhimiia [Biochemistry (Mosc)] 2021 Jul; Vol. 86 (7), pp. 878-886.
Typ publikacji :
Journal Article
MeSH Terms :
Reactive Oxygen Species*
Ditiocarb/*pharmacology
Glucose/*metabolism
Peas/*drug effects
Plant Epidermis/*drug effects
Superoxide Dismutase/*antagonists & inhibitors
Trientine/*pharmacology
Cell Death ; Chelating Agents/pharmacology ; Enzyme Inhibitors/pharmacology ; Glucose/pharmacology ; Peas/enzymology ; Peas/metabolism ; Peas/physiology ; Plant Epidermis/enzymology ; Plant Epidermis/metabolism ; Plant Epidermis/physiology ; Plant Leaves/drug effects ; Plant Leaves/enzymology ; Plant Leaves/metabolism ; Plant Leaves/physiology
Czasopismo naukowe
Tytuł :
Free Radicals and ROS Induce Protein Denaturation by UV Photostability Assay.
Autorzy :
Ruzza P; Padova Unit, Institute of Biomolecular Chemistry of CNR (ICB-CNR), Via F. Marzolo, 1, 35030 Padova, Italy.
Honisch C; Padova Unit, Institute of Biomolecular Chemistry of CNR (ICB-CNR), Via F. Marzolo, 1, 35030 Padova, Italy.; Department of Chemical Sciences, University of Padua, Via F. Marzolo, 1, 35030 Padova, Italy.
Hussain R; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
Siligardi G; Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 17; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Denaturation*/drug effects
Protein Denaturation*/radiation effects
Ultraviolet Rays*
Free Radicals/*chemistry
Proteins/*chemistry
Reactive Oxygen Species/*chemistry
Circular Dichroism ; Heating ; Reactive Oxygen Species/metabolism ; Spectrum Analysis ; Water/chemistry
Czasopismo naukowe
Tytuł :
Non-cytotoxic dosage of fumonisin B1 aggravates ochratoxin A-induced nephrocytotoxicity and apoptosis via ROS-dependent JNK/MAPK signaling pathway.
Autorzy :
Li H; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Wang M; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Kang W; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Lin Z; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Gan F; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China.
Huang K; College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; Institute of Nutritional and Metabolic Disorders in Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China; MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, Jiangsu Province, China. Electronic address: .
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Źródło :
Toxicology [Toxicology] 2021 Jun 15; Vol. 457, pp. 152802. Date of Electronic Publication: 2021 Apr 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Reactive Oxygen Species*/metabolism
Apoptosis/*drug effects
Fumonisins/*toxicity
Kidney/*drug effects
MAP Kinase Signaling System/*drug effects
Ochratoxins/*toxicity
Animals ; Apoptosis/physiology ; Cell Line ; Fumonisins/administration & dosage ; Kidney/metabolism ; Kidney/pathology ; Ochratoxins/administration & dosage ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Swine
Czasopismo naukowe
Tytuł :
Nrf2 activation is involved in osteogenic differentiation of periodontal ligament stem cells under cyclic mechanical stretch.
Autorzy :
Xi X; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Zhao Y; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Liu H; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Li Z; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Chen S; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China.
Liu D; School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University, China; Shandong Key Laboratory of Oral Tissue Regeneration, Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2021 Jun 15; Vol. 403 (2), pp. 112598. Date of Electronic Publication: 2021 Apr 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
NF-E2-Related Factor 2/*genetics
Osteoblasts/*metabolism
Reactive Oxygen Species/*metabolism
Stem Cells/*metabolism
Adolescent ; Animals ; Cell Differentiation ; Cell Survival/drug effects ; Child ; Collagen Type I/genetics ; Collagen Type I/metabolism ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Female ; Gene Expression Regulation ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Humans ; Hydroquinones/pharmacology ; Male ; Mechanotransduction, Cellular ; NAD(P)H Dehydrogenase (Quinone)/genetics ; NAD(P)H Dehydrogenase (Quinone)/metabolism ; NF-E2-Related Factor 2/antagonists & inhibitors ; NF-E2-Related Factor 2/metabolism ; Osteoblasts/cytology ; Osteoblasts/drug effects ; Osteogenesis/genetics ; Osteopontin/genetics ; Osteopontin/metabolism ; Periodontal Ligament/cytology ; Periodontal Ligament/drug effects ; Periodontal Ligament/metabolism ; Primary Cell Culture ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Rats ; Rats, Wistar ; Reactive Oxygen Species/antagonists & inhibitors ; Stem Cells/cytology ; Stem Cells/drug effects ; Stress, Mechanical ; Tooth Movement Techniques/methods
Czasopismo naukowe
Tytuł :
Acacia hydaspica R. Parker ethyl-acetate extract abrogates cisplatin-induced nephrotoxicity by targeting ROS and inflammatory cytokines.
Autorzy :
Afsar T; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. .
Razak S; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. .
Aldisi D; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Shabbir M; Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan.
Almajwal A; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Al Kheraif AA; Dental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Arshad M; Dental Biomaterials Research Chair, Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
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Źródło :
Scientific reports [Sci Rep] 2021 Aug 26; Vol. 11 (1), pp. 17248. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acacia/*chemistry
Acetates/*chemistry
Acute Kidney Injury/*prevention & control
Cytokines/*antagonists & inhibitors
Inflammation Mediators/*antagonists & inhibitors
Plant Extracts/*pharmacology
Reactive Oxygen Species/*antagonists & inhibitors
Acute Kidney Injury/chemically induced ; Acute Kidney Injury/metabolism ; Animals ; Cisplatin ; Colorectal Neoplasms/drug therapy ; Colorectal Neoplasms/metabolism ; Colorectal Neoplasms/pathology ; Cytokines/metabolism ; Disease Models, Animal ; HCT116 Cells ; Humans ; Inflammation Mediators/metabolism ; Male ; Mice, Nude ; Rats, Sprague-Dawley ; Reactive Oxygen Species/metabolism ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Tumor progress intercept by intervening in Caveolin-1 related intercellular communication via ROS-sensitive c-Myc targeting therapy.
Autorzy :
Zhou X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Liu X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Yang X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Wang L; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Hong Y; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Lian K; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Qiu G; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Shang X; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Ma Z; Ocean College, Zhejiang University, Zhoushan, 316021, China.
Yuan H; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China.
Hu F; College of Pharmaceutical Science, Zhejiang University, Hangzhou, 310058, China. Electronic address: .
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Źródło :
Biomaterials [Biomaterials] 2021 Aug; Vol. 275, pp. 120958. Date of Electronic Publication: 2021 Jun 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caveolin 1*
Exosomes*
Reactive Oxygen Species*
Neoplasms, Experimental/*drug therapy
Animals ; Cell Line, Tumor ; Drug Carriers ; Drug Liberation ; Female ; Mice ; Mice, Inbred BALB C ; Proto-Oncogene Proteins c-myc ; RAW 264.7 Cells ; Tumor Microenvironment
Czasopismo naukowe

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