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Tytuł:
A Vicious NGF-p75 Positive Feedback Loop Exacerbates the Toxic Effects of Oxidative Damage in the Human Retinal Epithelial Cell Line ARPE-19.
Autorzy:
Tringali G; Section of Pharmacology, Department of Healthcare Surveillance and Bioethics, Catholic University Medical School, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Pizzoferrato M; Section of Pharmacology, Department of Healthcare Surveillance and Bioethics, Catholic University Medical School, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Lisi L; Section of Pharmacology, Department of Healthcare Surveillance and Bioethics, Catholic University Medical School, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Marinelli S; European Brain Research Institute-Fondazione Rita Levi Montalcini, 00161 Rome, Italy.
Buccarello L; European Brain Research Institute-Fondazione Rita Levi Montalcini, 00161 Rome, Italy.
Falsini B; UOC Ophtalmology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.; Department of Ophthalmology, Bambino Gesù IRCCS Children's Hospital, 00133 Rome, Italy.
Cattaneo A; European Brain Research Institute-Fondazione Rita Levi Montalcini, 00161 Rome, Italy.; , Scuola Normale Superiore, 56124 Pisa, Italy.
Navarra P; Section of Pharmacology, Department of Healthcare Surveillance and Bioethics, Catholic University Medical School, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 12; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 12.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, trkA*/metabolism
Hydrogen Peroxide*/pharmacology
Humans ; Mice ; Animals ; Feedback ; Nerve Growth Factor/pharmacology ; Nerve Growth Factor/metabolism ; Receptors, Nerve Growth Factor/metabolism ; Receptor, Nerve Growth Factor/metabolism ; Cell Line ; Oxidative Stress ; Epithelial Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An Update on Toll-like Receptor 2, Its Function and Dimerization in Pro- and Anti-Inflammatory Processes.
Autorzy:
Colleselli K; Department of Medical and Pharmaceutical Biotechnology, IMC University of Applied Sciences, 3500 Krems, Austria.
Stierschneider A; Department of Medical and Pharmaceutical Biotechnology, IMC University of Applied Sciences, 3500 Krems, Austria.
Wiesner C; Department of Medical and Pharmaceutical Biotechnology, IMC University of Applied Sciences, 3500 Krems, Austria.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 05; Vol. 24 (15). Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Toll-Like Receptor 2*/metabolism
Toll-Like Receptor 1*/metabolism
Humans ; Dimerization ; Toll-Like Receptors ; Anti-Inflammatory Agents ; Toll-Like Receptor 6/metabolism ; Toll-Like Receptor 10
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Interaction of Synthetic Cannabinoid Receptor Agonists with Cannabinoid Receptor I: Insights into Activation Molecular Mechanism.
Autorzy:
Gavryushov S; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Vavilova Str. 32, Moscow 119991, Russia.; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya Str., Moscow 119991, Russia.
Bashilov A; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya Str., Moscow 119991, Russia.; Skolkovo Institute of Science and Technology, Bolshoy Boulevard 30, Bld. 1, Moscow 121205, Russia.
Cherashev-Tumanov KV; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya Str., Moscow 119991, Russia.
Kuzmich NN; The Maurice and Vivienne Wohl Institute for Drug Discovery, Weizmann Institute of Science, Rehovot 7610001, Israel.
Burykina TI; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya Str., Moscow 119991, Russia.
Izotov BN; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 2-4 Bolshaya Pirogovskaya Str., Moscow 119991, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 03; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
Cannabinoid Receptor Agonists*/pharmacology
Cannabinoid Receptor Agonists*/chemistry
Molecular Dynamics Simulation*
Ligands ; Receptors, Cannabinoid ; Receptor, Cannabinoid, CB1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Expression of Toll-like Receptors in Stem Cells of the Apical Papilla and Its Implication for Regenerative Endodontics.
Autorzy:
Takimoto K; Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Widbiller M; Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.; Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, 93053 Regensburg, Germany.
Diogenes A; Department of Endodontics, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
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Źródło:
Cells [Cells] 2023 Oct 21; Vol. 12 (20). Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toll-Like Receptor 2*
Regenerative Endodontics*
Toll-Like Receptor 4 ; Toll-Like Receptor 3 ; Escherichia coli ; Toll-Like Receptors ; Stem Cells ; Ligands
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional Interaction between Adenosine A 2A and mGlu 5 Receptors Mediates STEP Phosphatase Activation and Promotes STEP/mGlu 5 R Binding in Mouse Hippocampus and Neuroblastoma Cell Line.
Autorzy:
Mallozzi C; Department of Neuroscience, Istituto Superiore di Sanità, 00161 Rome, Italy.
Pepponi R; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Gaddini L; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Casella I; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Chiodi V; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Popoli P; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
Domenici MR; National Centre for Drug Research and Evaluation, Istituto Superiore di Sanità, 00161 Rome, Italy.
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Źródło:
Biomolecules [Biomolecules] 2023 Sep 05; Vol. 13 (9). Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptor, Adenosine A2A*/metabolism
Neuroblastoma*
Humans ; Mice ; Animals ; Receptor, Metabotropic Glutamate 5/metabolism ; Adenosine/pharmacology ; Cell Line ; Hippocampus/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Necrotic Cells from Head and Neck Carcinomas Release Biomolecules That Are Activating Toll-like Receptor 3.
Autorzy:
Vasiljevic T; Laboratory for Personalized Medicine, Division of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.
Tarle M; Department of Maxillofacial Surgery, Dubrava University Hospital, School of Medicine, University of Zagreb, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia.; School of Dental Medicine, University of Zagreb, Gunduliceva 5, 10000 Zagreb, Croatia.
Hat K; Department of Maxillofacial Surgery, Dubrava University Hospital, School of Medicine, University of Zagreb, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia.
Luksic I; Department of Maxillofacial Surgery, Dubrava University Hospital, School of Medicine, University of Zagreb, Gojko Šušak Avenue 6, 10000 Zagreb, Croatia.
Mikulandra M; Division of Oncology and Radiotherapy, University Hospital for Tumors, Sestre Milosrdnice University Hospital Center, Vinogradska Cesta 29, 10000 Zagreb, Croatia.
Busson P; CNRS-UMR 9018-METSY, Gustave Roussy Institute, Université Paris-Saclay, 39 rue Camille Desmoulins, 94805 Villejuif CEDEX, France.
Matijevic Glavan T; Laboratory for Personalized Medicine, Division of Molecular Medicine, Rudjer Boskovic Institute, Bijenicka 54, 10000 Zagreb, Croatia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 17; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Head and Neck Neoplasms*
Toll-Like Receptor 3*/metabolism
Animals ; Humans ; Mice ; Necrosis/metabolism ; Squamous Cell Carcinoma of Head and Neck ; Toll-Like Receptor 9 ; Toll-Like Receptors ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AXL receptor tyrosine kinase modulates gonadotropin-releasing hormone receptor signaling.
Autorzy:
Mohammadzadeh P; Department of Biomedical Sciences, Colorado State University, 1617 Campus Delivery, Fort Collins, CO, 80523, USA.
Roueinfar M; Department of Biomedical Sciences, Colorado State University, 1617 Campus Delivery, Fort Collins, CO, 80523, USA.
Amberg GC; Department of Biomedical Sciences, Colorado State University, 1617 Campus Delivery, Fort Collins, CO, 80523, USA. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2023 Oct 12; Vol. 21 (1), pp. 284. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, LHRH*/metabolism
Axl Receptor Tyrosine Kinase*
Mice ; Humans ; Animals ; Matrix Metalloproteinase 9/metabolism ; Signal Transduction ; Gonadotropin-Releasing Hormone/metabolism ; Gonadotropin-Releasing Hormone/pharmacology ; Receptor Protein-Tyrosine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cognitive Alterations in Old Mice Are Associated with Intestinal Barrier Dysfunction and Induced Toll-like Receptor 2 and 4 Signaling in Different Brain Regions.
Autorzy:
Brandt A; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
Kromm F; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
Hernández-Arriaga A; Animal Nutrition Department, Institute of Animal Science, University of Hohenheim, 70593 Stuttgart, Germany.
Martínez Sánchez I; Department of Neuroscience, Karolinska Institute, Biomedicum, 17177 Stockholm, Sweden.
Bozkir HÖ; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
Staltner R; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
Baumann A; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
Camarinha-Silva A; Animal Nutrition Department, Institute of Animal Science, University of Hohenheim, 70593 Stuttgart, Germany.
Heijtz RD; Department of Neuroscience, Karolinska Institute, Biomedicum, 17177 Stockholm, Sweden.
Bergheim I; Department of Nutritional Sciences, Molecular Nutritional Science, University of Vienna, 1090 Vienna, Austria.
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Źródło:
Cells [Cells] 2023 Aug 27; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Toll-Like Receptor 2*
Gastrointestinal Diseases*
Male ; Animals ; Mice ; Mice, Inbred C57BL ; Ligands ; Toll-Like Receptor 4 ; Brain ; Cognition
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
[Tyro3 and CDK9 as biomarkers for drug resistance to breast cancer anti-PD-1 therapies].
Autorzy:
Zhang JF; Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin 150086, China.
Liu T; Department of Breast Surgery, Harbin Medical University Cancer Hospital, Harbin 150086, China.
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Źródło:
Zhonghua zhong liu za zhi [Chinese journal of oncology] [Zhonghua Zhong Liu Za Zhi] 2023 Aug 23; Vol. 45 (8), pp. 651-656.
Typ publikacji:
English Abstract; Journal Article
MeSH Terms:
Receptor Protein-Tyrosine Kinases*/genetics
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/genetics
Humans ; Animals ; Mice ; c-Mer Tyrosine Kinase/genetics ; c-Mer Tyrosine Kinase/metabolism ; Axl Receptor Tyrosine Kinase ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; B7-H1 Antigen/genetics ; Drug Resistance, Neoplasm ; Biomarkers ; Cell Line, Tumor ; Cyclin-Dependent Kinase 9
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Getting Your Laboratory on Track With Neurotrophic Receptor Tyrosine Kinase.
Autorzy:
Eyerer FIR; From the Department of Pathology and Laboratory Medicine, University of Vermont Medical Center; Burlington (Eyerer).
Bradshaw G; Proficiency Testing, College of American Pathologists, Northfield, Illinois (Bradshaw, Vasalos).
Vasalos P; Proficiency Testing, College of American Pathologists, Northfield, Illinois (Bradshaw, Vasalos).
Laser JS; Everly Health; Austin, Texas (Laser).
Chang CC; AdventHealth-Orlando, Orlando, Florida (Chang).; Department of Pathology, College of Medicine, University of Central Florida, Orlando (Chang).
Kim AS; Department of Pathology, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Kim).
Olson DR; Department of Pathology and Laboratory Medicine, Children's Minnesota, Minneapolis (Olson).
Paler RJ; Labcorp Oncology, Laboratory Corporation of America Holdings, Phoenix, Arizona (Paler).
Rosenbaum JN; Department of Pathology, Kaiser Permanente, San Jose, California (Rosenbaum).
Walk EE; Department of Medical, Regulatory and Clinical Affairs, PathAI, Boston, Massachusetts (Walk).
Willis JE; Department of Pathology, Case Western Reserve University/Cleveland Medical Center, Cleveland, Ohio (Willis).
Yao J; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (Yao).
Yohe SL; The Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (Yohe).
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2023 Aug 01; Vol. 147 (8), pp. 872-884.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, trkA*/genetics
Neoplasms*/diagnosis
Neoplasms*/genetics
Neoplasms*/drug therapy
Humans ; Receptor, trkC/genetics ; In Situ Hybridization, Fluorescence ; Laboratories ; Oncogene Proteins, Fusion/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Neurotrophin Analog ENT-A044 Activates the p75 Neurotrophin Receptor, Regulating Neuronal Survival in a Cell Context-Dependent Manner.
Autorzy:
Papadopoulou MA; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Rogdakis T; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Charou D; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Peteinareli M; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Ntarntani K; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Gravanis A; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Chanoumidou K; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
Charalampopoulos I; Department of Pharmacology, Medical School, University of Crete, 71003 Heraklion, Greece.; Institute of Molecular Biology & Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), 70013 Heraklion, Greece.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 20; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 20.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Nerve Growth Factor*/metabolism
Nerve Growth Factors*/pharmacology
Nerve Growth Factors*/metabolism
Humans ; Receptors, Nerve Growth Factor/metabolism ; Receptor, trkB/metabolism ; Signal Transduction/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Vomeronasal Receptors Associated with Circulating Estrogen Processing Chemosensory Cues in Semi-Aquatic Mammals.
Autorzy:
Xie W; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Chen M; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Shen Y; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Liu Y; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Zhang H; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
Weng Q; Laboratory of Animal Physiology, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 27; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Estrogen Receptor alpha*/metabolism
Vomeronasal Organ*/metabolism
Animals ; Female ; Estrogen Receptor beta/genetics ; Estrogen Receptor beta/metabolism ; Cues ; Mammals/metabolism ; Estrogens/metabolism ; Arvicolinae
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3- b ]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Autorzy:
Mugnaini C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Kostrzewa M; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli, Italy.
Casini M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Kumar P; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli, Italy.
Catallo V; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Allarà M; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli, Italy.
Guastaferro L; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Brizzi A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Paolino M; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Tafi A; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Kapatais C; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Giorgi G; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Vacondio F; Department of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Mor M; Department of Food and Drug, University of Parma, Parco Area delle Scienze 27/A, 43124 Parma, Italy.
Corelli F; Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, Italy.
Ligresti A; National Research Council of Italy, Institute of Biomolecular Chemistry, 80078 Pozzuoli, Italy.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Jun 24; Vol. 28 (13). Date of Electronic Publication: 2023 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Cannabinoid, CB2*
Cannabinoids*
Ligands ; Drug Inverse Agonism ; Structure-Activity Relationship ; Pyridines ; Receptor, Cannabinoid, CB1
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Evidence That DDR1 Promotes Oligodendrocyte Differentiation during Development and Myelin Repair after Injury.
Autorzy:
Mei R; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.; Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou 310022, China.
Qiu W; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Yang Y; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Xu S; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Rao Y; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Li Q; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Luo Y; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Huang H; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Yang A; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Tao H; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Qiu M; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Zhao X; Zhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 311121, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 19; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:
Journal Article
MeSH Terms:
Discoidin Domain Receptor 1*/genetics
Discoidin Domain Receptor 1*/metabolism
Myelin Sheath*/metabolism
Oligodendroglia*/metabolism
Animals ; Female ; Male ; Mice ; Cell Differentiation ; Central Nervous System ; Mice, Knockout ; Neurogenesis ; Receptor Protein-Tyrosine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation.
Autorzy:
Wang K; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Box 582, Sweden.
Papadopoulos N; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Box 582, Sweden.
Hamidi A; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Box 582, Sweden.
Lennartsson J; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden.
Heldin CH; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Box 582, Sweden. .
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Źródło:
BMC molecular and cell biology [BMC Mol Cell Biol] 2023 May 16; Vol. 24 (1), pp. 19. Date of Electronic Publication: 2023 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Receptor, Platelet-Derived Growth Factor alpha*/metabolism
Sumoylation*
Phospholipase C gamma/metabolism ; Lysine/metabolism ; Phosphorylation ; Receptor Protein-Tyrosine Kinases/metabolism ; Cell Proliferation ; Platelet-Derived Growth Factor/pharmacology ; Platelet-Derived Growth Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A2BAR Antagonism Decreases the Glomerular Expression and Secretion of Chemoattractants for Monocytes and the Pro-Fibrotic M2 Macrophages Polarization during Diabetic Nephropathy.
Autorzy:
Torres-Arévalo Á; Escuela de Medicina Veterinaria, Facultad de Medicina Veterinaria Y Recursos Naturales, Sede Talca, Universidad Santo Tomás, Talca 347-3620, Chile.
Nahuelpán Y; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Muñoz K; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Jara C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Cappelli C; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Taracha-Wiśniewska A; Faculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, 02-106 Warsaw, Poland.
Quezada-Monrás C; Tumor Biology Laboratory, Institute of Biochemistry and Microbiology, Faculty of Sciences, Universidad Austral de Chile, Valdivia 511-0566, Chile.; Millennium Institute on Immunology and Immunotherapy, Universidad Austral de Chile, Valdivia 511-0566, Chile.
Martín RS; Laboratorio de Patología Molecular, Instituto de Bioquímica Y Microbiología, Universidad Austral de Chile, Valdivia 511-0566, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 29; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 29.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Nephropathies*/genetics
Diabetic Nephropathies*/immunology
Kidney Glomerulus*/drug effects
Kidney Glomerulus*/metabolism
Chemotactic Factors*/antagonists & inhibitors
Chemotactic Factors*/genetics
Chemotactic Factors*/metabolism
Cell Polarity*/drug effects
Cell Polarity*/immunology
Macrophages*/drug effects
Macrophages*/immunology
Adenosine A2 Receptor Antagonists*/pharmacology
Acetamides*/pharmacology
Purines*/pharmacology
Receptor, Adenosine A2B ; Animals ; Rats ; Cell Movement/drug effects ; Male ; Rats, Sprague-Dawley ; Transcription, Genetic/drug effects ; Protein Biosynthesis/drug effects ; Immunity/drug effects ; Immunity/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
AXL in cancer: a modulator of drug resistance and therapeutic target.
Autorzy:
Tang Y; Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Zang H; Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Wen Q; Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. .
Fan S; Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Jun 16; Vol. 42 (1), pp. 148. Date of Electronic Publication: 2023 Jun 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Axl Receptor Tyrosine Kinase*
Neoplasms*/drug therapy
Neoplasms*/genetics
Humans ; c-Mer Tyrosine Kinase/metabolism ; Drug Resistance, Neoplasm ; Proto-Oncogene Proteins/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Isoflavones Mediate Dendritogenesis Mainly through Estrogen Receptor α.
Autorzy:
Ariyani W; Metabolic Signal Research Center, Institute for Molecular and Cellular Regulation, Gunma University, 3-39-15 Showa-machi, Maebashi 371-8512, Japan.; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
Amano I; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
Koibuchi N; Department of Integrative Physiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi 371-8511, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 19; Vol. 24 (10). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article
MeSH Terms:
Estrogen Receptor alpha*/genetics
Isoflavones*/pharmacology
Animals ; Mice ; Fulvestrant ; Genistein/pharmacology ; Receptors, Estrogen/genetics ; Receptors, Estrogen/metabolism ; Estrogen Receptor beta/metabolism ; Estradiol/pharmacology ; Estrogens
Czasopismo naukowe
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Tytuł:
C2-linked alkynyl poly-ethylene glycol(PEG) adenosine conjugates as water-soluble adenosine receptor agonists.
Autorzy:
Ferguson L; School of Science, University of the West of Scotland, Paisley, UK.
Madieh NS; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
Vaideanu A; UCL School of Pharmacy, University College London, London, UK.
Schatzlein A; UCL School of Pharmacy, University College London, London, UK.
Festa J; Leicester School of Allied Health Sciences, De Montfort University, Leicester, UK.
Singh H; Leicester School of Allied Health Sciences, De Montfort University, Leicester, UK.
Wells G; UCL School of Pharmacy, University College London, London, UK.
Bhakta S; Department of Biological Sciences, Institute of Structural and Molecular Biology, Birkbeck, University of London, London, UK.
Brucoli F; Leicester School of Pharmacy, De Montfort University, Leicester, UK.
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Źródło:
Chemical biology & drug design [Chem Biol Drug Des] 2023 Feb; Vol. 101 (2), pp. 340-349. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenosine*/pharmacology
Adenosine*/metabolism
Purinergic P1 Receptor Agonists*
Mice ; Animals ; Polyethylene Glycols ; Receptors, Purinergic P1/metabolism ; Protein Binding ; Receptor, Adenosine A2A/metabolism ; Receptor, Adenosine A3
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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