Temat: "Receptor, ErbB-2" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Misconception on the duration of ado-trastuzumab emtansine treatment for HER2-positive early breast cancer.
Autorzy:: Chung C; Houston Methodist West Hospital Houston, TX, USA.; Pokaż więcej
Źródło:: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2022 May 06; Vol. 79 (10), pp. 717-718.
Typ publikacji:: Journal Article; Comment
MeSH Terms:: Breast Neoplasms*/drug therapy
Maytansine*/adverse effects
Ado-Trastuzumab Emtansine ; Antibodies, Monoclonal, Humanized/adverse effects ; Antineoplastic Combined Chemotherapy Protocols ; Female ; Humans ; Receptor, ErbB-2/therapeutic use ; Trastuzumab/therapeutic use

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: FDA approves pertuzumab for breast cancer.
Autorzy:: Traynor K; Pokaż więcej
Źródło:: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists [Am J Health Syst Pharm] 2012 Jul 15; Vol. 69 (14), pp. 1178.
Typ publikacji:: Wiadomości
MeSH Terms:: Drug Approval*/legislation & jurisprudence
Receptor, ErbB-2*/antagonists & inhibitors
Receptor, ErbB-2*/metabolism
Antibodies, Monoclonal, Humanized/*therapeutic use
Breast Neoplasms/*drug therapy
Antibodies, Monoclonal, Humanized/pharmacology ; Breast Neoplasms/metabolism ; Female ; Humans

Periodyk

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Granting specificity for breast cancer cells using a hepatitis B core particle with a HER2-targeted affibody molecule.
Autorzy:: Nishimura Y; Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan.
Mimura W
Mohamed Suffian IF
Amino T
Ishii J
Ogino C
Kondo A; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2013 Mar; Vol. 153 (3), pp. 251-6. Date of Electronic Publication: 2012 Dec 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hepatitis B virus/*metabolism
Protein Engineering/*methods
Receptor, ErbB-2/*metabolism
Viral Core Proteins/*metabolism
Binding Sites/genetics ; Binding, Competitive ; Blotting, Western ; Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Drug Delivery Systems/methods ; HeLa Cells ; Hepatitis B virus/genetics ; Humans ; MCF-7 Cells ; Microscopy, Atomic Force ; Microscopy, Confocal ; Mutation ; Protein Binding ; Receptor, ErbB-2/genetics ; Recombinant Fusion Proteins/administration & dosage ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Sequence Deletion ; Viral Core Proteins/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Erbin-regulated sensitivity of MCF-7 breast cancer cells to TRAIL via ErbB2/AKT/NF-kappaB pathway.
Autorzy:: Liu N; National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, 5 Dong Dan San Tiao, Beijing 100005, China.
Zhang J
Zhang J
Liu S
Liu Y
Zheng D; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2008 Jun; Vol. 143 (6), pp. 793-801. Date of Electronic Publication: 2008 Mar 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Signal Transduction*
Adaptor Proteins, Signal Transducing/*pharmacology
Breast Neoplasms/*metabolism
NF-kappa B/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
Receptor, ErbB-2/*metabolism
TNF-Related Apoptosis-Inducing Ligand/*pharmacology
Acetophenones/pharmacology ; Adaptor Proteins, Signal Transducing/antagonists & inhibitors ; Adaptor Proteins, Signal Transducing/genetics ; Apoptosis/physiology ; Benzopyrans/pharmacology ; Blotting, Western ; Breast Neoplasms/pathology ; Caspases ; Enzyme Inhibitors/pharmacology ; Female ; Humans ; I-kappa B Kinase/metabolism ; Immunoblotting ; Immunoprecipitation ; NF-kappa B/genetics ; Phosphorylation/drug effects ; RNA, Small Interfering/pharmacology ; Receptor, ErbB-2/antagonists & inhibitors ; Receptor, ErbB-2/genetics

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Machine learning approaches to decipher hormone and HER2 receptor status phenotypes in breast cancer.
Autorzy:: Adabor ES; Stellenbosch University.
Acquaah-Mensah GK; armaceutical Sciences Department, Massachusetts College of Pharmacy and Health Sciences, USA.; Pokaż więcej
Źródło:: Briefings in bioinformatics [Brief Bioinform] 2019 Mar 22; Vol. 20 (2), pp. 504-514.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Machine Learning*
Breast Neoplasms/*classification
Breast Neoplasms/*metabolism
Gene Expression Profiling/*methods
Receptor, ErbB-2/*metabolism
Algorithms ; Biomarkers, Tumor/metabolism ; Breast Neoplasms/genetics ; Computational Biology/methods ; Female ; Humans ; Phenotype ; Prognosis ; Receptors, Estrogen/metabolism ; Receptors, Progesterone/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Characterization of glycoengineered anti-HER2 monoclonal antibodies produced by using a silkworm-baculovirus expression system.
Autorzy:: Egashira Y; Department of Bioengineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan.; Protein Development Center, Sysmex Corporation, Sayama, Saitama 350-1332, Japan.
Nagatoishi S; Department of Bioengineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan.; Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.
Kiyoshi M; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, Kanagawa 210-9501, Japan.
Ishii-Watabe A; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, Kanagawa 210-9501, Japan.
Tsumoto K; Department of Bioengineering, School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo 113-8656, Japan.; Institute of Medical Science, The University of Tokyo, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2018 Jun 01; Vol. 163 (6), pp. 481-488.
Typ publikacji:: Journal Article
MeSH Terms:: Protein Engineering*
Antibodies, Monoclonal/*biosynthesis
Antibodies, Monoclonal/*genetics
Antibodies, Monoclonal/*immunology
Baculoviridae/*metabolism
Bombyx/*virology
Receptor, ErbB-2/*immunology
Animals ; Antibodies, Monoclonal/isolation & purification ; Baculoviridae/genetics ; CHO Cells ; Chromatography, Liquid ; Cricetulus ; Gene Expression ; Glycosylation ; Polysaccharides/analysis ; Tandem Mass Spectrometry

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Small Bowel Carcinomas in Coeliac or Crohn's Disease: Clinico-pathological, Molecular, and Prognostic Features. A Study From the Small Bowel Cancer Italian Consortium.
Autorzy:: Vanoli A; Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Di Sabatino A; Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Furlan D; Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Klersy C; Biometry and Statistics Service, San Matteo Hospital, Pavia, Italy.
Grillo F; Pathology Unit, Department of Surgical and Diagnostic Sciences, San Martino/IST University Hospital, Genova, Italy.
Fiocca R; Pathology Unit, Department of Surgical and Diagnostic Sciences, San Martino/IST University Hospital, Genova, Italy.
Mescoli C; Pathology Unit, Department of Medicine, University of Padua, Padua, Italy.
Rugge M; Pathology Unit, Department of Medicine, University of Padua, Padua, Italy.
Nesi G; Division of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.
Fociani P; Units of Pathology.
Sampietro G; IBD Surgery.
Ardizzone S; Gastroenterology, Luigi Sacco University Hospital, Milan, Italy.
Luinetti O; Departments of Molecular Medicine.
Calabrò A; Departments of Experimental and Clinical Biomedical Sciences.
Tonelli F; Surgery and Translational Medicine, University of Florence, Florence, Italy.
Volta U; Divisions of Gastroenterology.
Santini D; Pathology, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Caio G; Divisions of Gastroenterology.
Giuffrida P; Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Elli L; Center for Prevention and Diagnosis of Coeliac Disease, Fondazione IRCCS Ca' Granda, Milan, Italy.
Ferrero S; Division of Pathology, Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.
Latella G; Gastroenterology Unit, Department of Life and Enviromental Sciences, University of L'Aquila, L'Aquila, Italy.
Ciardi A; Departments of Radiological, Oncological, Pathological Sciences.
Caronna R; Surgical Sciences, Umberto I Hospital, La Sapienza University, Rome, Italy.
Solina G; Units of General Surgery.
Rizzo A; Pathology, Cervello Hospital, Palermo, Italy.
Ciacci C; Department of Medicine and Surgery, University of Salerno, Salerno, Italy.
D'Armiento FP; Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Salemme M; Pathology Section, Spedali Civili Hospital, Brescia, Italy.
Villanacci V; Pathology Section, Spedali Civili Hospital, Brescia, Italy.
Cannizzaro R; Departments of Gastroenterology.
Canzonieri V; Pathology, National Cancer Institute, Aviano, Italy.
Reggiani Bonetti L; Section of Pathology, Department of Diagnostic Medicine and Public Health, University of Modena and Reggio Emilia, Modena, Italy.
Biancone L; Departments of Systems Medicine.
Monteleone G; Departments of Systems Medicine.
Orlandi A; Biopathology and Image Diagnostics, University of Tor Vergata, Rome, Italy.
Santeusanio G; Biopathology and Image Diagnostics, University of Tor Vergata, Rome, Italy.
Macciomei MC; Pathology Unit, San Camillo-Forlanini Hospital, Rome, Italy.
D'Incà R; Gastroenterology Section, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Perfetti V; Internal Medicine, S.S. Annunziata Hospital, ASST-Pavia, Varzi, Italy.
Sandri G; Clinical Nutrition Unit, Sant'Eugenio Hospital, Rome, Italy.
Silano M; Unit of Human Nutrition and Health, Istituto Superiore di Sanità, Rome, Italy.
Florena AM; Institute of Pathologic Anatomy, Giaccone University Hospital, University of Palermo, Palermo, Italy.
Giannone AG; Institute of Pathologic Anatomy, Giaccone University Hospital, University of Palermo, Palermo, Italy.
Papi C; Units of IBD.
Coppola L; Pathologic Anatomy, San Filippo Neri Hospital, Rome, Italy.
Usai P; Department of Internal Medicine, University of Cagliari, Cagliari, Italy.
Maccioni A; Pathology Unit, SS. Trinità Hospital, Cagliari, Italy.
Astegiano M; General and Specialistic Surgery, Città della Salute e della Scienza-Molinette Hospital, Turin, Italy.
Migliora P; Unit of Pathological Anatomy, Sant'Andrea Hospital, Vercelli, Italy.
Manca R; Departments of Molecular Medicine.
Martino M; Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Trapani D; Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Cerutti R; Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Alberizzi P; Departments of Molecular Medicine.
Riboni R; Departments of Molecular Medicine.
Sessa F; Department of Surgical and Morphological Sciences, University of Insubria, Varese, Italy.
Paulli M; Departments of Molecular Medicine.
Solcia E; Departments of Molecular Medicine.
Corazza GR; Internal Medicine, San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.; Pokaż więcej
Źródło:: Journal of Crohn's & colitis [J Crohns Colitis] 2017 Aug 01; Vol. 11 (8), pp. 942-953.
Typ publikacji:: Journal Article
MeSH Terms:: Celiac Disease/*complications
Colonic Neoplasms/*etiology
Crohn Disease/*complications
Adult ; Aged ; Aged, 80 and over ; Celiac Disease/diagnosis ; Celiac Disease/genetics ; Celiac Disease/pathology ; Child ; Class I Phosphatidylinositol 3-Kinases/genetics ; Colonic Neoplasms/diagnosis ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Crohn Disease/diagnosis ; Crohn Disease/genetics ; Crohn Disease/pathology ; Humans ; Male ; Microsatellite Instability ; Middle Aged ; Prognosis ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras)/genetics ; Receptor, ErbB-2/genetics ; Retrospective Studies ; Risk Factors ; Survival Analysis ; Tumor Suppressor Protein p53/genetics ; Young Adult

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: Fluorescence in situ hybridization identifies high risk Barrett's patients likely to develop esophageal adenocarcinoma.
Autorzy:: Brankley SM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Halling KC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Jenkins SM; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA.
Timmer MR; Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Iyer PG; Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Smyrk TC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Barr Fritcher EG; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Voss JS; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Kipp BR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Campion MB; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Lutzke LS; Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.
Minot DM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.
Wang KK; Department of Gastroenterology, Mayo Clinic, Rochester, Minnesota, USA.; Pokaż więcej
Źródło:: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus [Dis Esophagus] 2016 Aug; Vol. 29 (6), pp. 513-9. Date of Electronic Publication: 2015 Jun 05.
Typ publikacji:: Journal Article
MeSH Terms:: Adenocarcinoma/*genetics
Barrett Esophagus/*genetics
Cyclin-Dependent Kinase Inhibitor p18/*genetics
Esophageal Neoplasms/*genetics
In Situ Hybridization, Fluorescence/*methods
Proto-Oncogene Proteins c-myc/*genetics
Receptor, ErbB-2/*genetics
Trans-Activators/*genetics
Adenocarcinoma/pathology ; Aged ; Barrett Esophagus/pathology ; Cohort Studies ; Cyclin-Dependent Kinase Inhibitor p16 ; DNA Probes ; Disease Progression ; Esophageal Neoplasms/pathology ; Esophagoscopy ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Assessment
SCR Disease Name:: Adenocarcinoma Of Esophagus

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Effect of trastuzumab interchain disulfide bond cleavage on Fcγ receptor binding and antibody-dependent tumour cell phagocytosis.
Autorzy:: Suzuki M; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and Teijin Pharma Limited, 4-3-2 Asahigaoka, Hino-shi, Tokyo 191-8512, Japan .
Yamanoi A; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.
Machino Y; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.
Ootsubo M; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.
Izawa K; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.
Kohroki J; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.
Masuho Y; Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Chiba 278-8510, Japan and.; Pokaż więcej
Źródło:: Journal of biochemistry [J Biochem] 2016 Jan; Vol. 159 (1), pp. 67-76. Date of Electronic Publication: 2015 Aug 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antibody-Dependent Cell Cytotoxicity*
Cytophagocytosis*
Antineoplastic Agents/*chemistry
Neoplasms/*immunology
Receptors, IgG/*immunology
Trastuzumab/*chemistry
Alkylation ; Antibody Affinity ; Antineoplastic Agents/immunology ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Humans ; Immunoglobulin G/chemistry ; Immunoglobulin G/immunology ; Iodoacetamide/chemistry ; Maleimides/chemistry ; Neoplasms/drug therapy ; Protein Structure, Secondary ; Receptor, ErbB-2/metabolism ; Trastuzumab/immunology ; Trastuzumab/therapeutic use