Temat: "Receptor, Melanocortin, Type 3" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The Parallel Structure-Activity Relationship Screening of Three Compounds Identifies the Common Agonist Pharmacophore of Pyrrolidine Bis-Cyclic Guanidine Melanocortin-3 Receptor (MC3R) Small-Molecule Ligands.
Autorzy:: Ericson MD; Department of Medicinal Chemistry & Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.
Freeman KT; Department of Medicinal Chemistry & Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.
LaVoi TM; Center for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Donow HM; Center for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Santos RG; Department of Mathematics, Nova Southeastern University, Fort Lauderdale, FL 33314, USA.
Giulianotti MA; Center for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Pinilla C; Center for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Houghten RA; Center for Translational Science, Florida International University, Port St. Lucie, FL 34987, USA.
Haskell-Luevano C; Department of Medicinal Chemistry & Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 14; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:: Journal Article
MeSH Terms:: Receptor, Melanocortin, Type 3*/agonists
Receptor, Melanocortin, Type 3*/metabolism
Pharmacophore*
Guanidine/pharmacology ; Ligands ; Receptors, Melanocortin/metabolism ; Guanidines ; Structure-Activity Relationship

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Tytuł:: Evaluation of the MC3R gene pertaining to body weight and height regulation and puberty development.
Autorzy:: Zheng Y; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, 45147, Essen, Germany. .; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. .
Rajcsanyi LS; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, 45147, Essen, Germany.; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Peters T; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, 45147, Essen, Germany.; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Dempfle A; Institute of Medical Informatics and Statistics, Kiel University, Kiel, Germany.
Wudy SA; Division of Pediatric Endocrinology and Diabetology, Center of Child and Adolescent Medicine, Justus Liebig University, Giessen, Germany.
Hebebrand J; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, 45147, Essen, Germany.; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Hinney A; Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Essen, University of Duisburg-Essen, Virchowstr. 174, 45147, Essen, Germany.; Center for Translational Neuro- and Behavioral Sciences, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Jun 27; Vol. 13 (1), pp. 10419. Date of Electronic Publication: 2023 Jun 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptor, Melanocortin, Type 3*/genetics
Obesity, Morbid*/genetics
Male ; Child ; Adolescent ; Humans ; Female ; Body Weight/genetics ; Obesity/genetics ; Body Mass Index ; Puberty/genetics ; Body Height/genetics

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Skocz do pozycji: 3.

Tytuł:: Specific Functions of Melanocortin 3 Receptor (MC3R)
Autorzy:: Yanik T; Middle East Technical University, Department of Biological Sciences, Ankara, Turkey
Durhan ST; Middle East Technical University, Department of Biochemistry, Ankara, Turkey; Pokaż więcej
Źródło:: Journal of clinical research in pediatric endocrinology [J Clin Res Pediatr Endocrinol] 2023 Feb 27; Vol. 15 (1), pp. 1-6. Date of Electronic Publication: 2022 Sep 02.
Typ publikacji:: Review; Journal Article
MeSH Terms:: Receptor, Melanocortin, Type 3*/genetics
Circadian Rhythm*
Animals ; Humans ; Mammals

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Skocz do pozycji: 4.

Tytuł:: Generation of an MC3R knock-out pig by CRSPR/Cas9 combined with somatic cell nuclear transfer (SCNT) technology.
Autorzy:: Yin Y; College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing, 314001, China.
Hao H; State Key Laboratory of Agrobiotechnology & College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Xu X; College of life science and biotechnology, Hebei Normal University of Science and Technology, Qinhuangdao, 066004, China.
Shen L; State Key Laboratory of Agrobiotechnology & College of Biological Sciences, China Agricultural University, Beijing, 100193, China.
Wu W; College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing, 314001, China.
Zhang J; College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing, 314001, China. .; College of life science and biotechnology, Hebei Normal University of Science and Technology, Qinhuangdao, 066004, China. .
Li Q; State Key Laboratory of Agrobiotechnology & College of Biological Sciences, China Agricultural University, Beijing, 100193, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2019 May 28; Vol. 18 (1), pp. 122. Date of Electronic Publication: 2019 May 28.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Knockout Techniques*
Nuclear Transfer Techniques*
CRISPR-Cas Systems/*genetics
Receptor, Melanocortin, Type 3/*deficiency
Adiposity ; Animals ; Animals, Genetically Modified ; Base Sequence ; Body Weight ; Fetus/cytology ; Fibroblasts/metabolism ; Gene Targeting ; Genetic Vectors/metabolism ; RNA, Guide, CRISPR-Cas Systems/metabolism ; Receptor, Melanocortin, Type 3/metabolism ; Swine

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Skocz do pozycji: 5.

Tytuł:: Regulation of Melanocortin-3 and -4 Receptors by Isoforms of Melanocortin-2 Receptor Accessory Protein 1 and 2.
Autorzy:: Ji RL; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
Tao YX; Department of Anatomy, Physiology and Pharmacology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2022 Feb 02; Vol. 12 (2). Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Melanocortins*/metabolism
Receptor, Melanocortin, Type 2*
Humans ; Protein Isoforms/genetics ; Receptor, Melanocortin, Type 3/genetics ; Receptor, Melanocortin, Type 3/metabolism ; Receptors, Melanocortin/metabolism

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Skocz do pozycji: 6.

Tytuł:: Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats.
Autorzy:: You P; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Hu H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Chen Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Zhao Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Yang Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Wang T; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Xing R; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Shao Y; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Zhang W; School of Life Sciences, East China Normal University, Shanghai 200241, China.
Li D; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Chen H; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.
Liu M; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences, Shanghai 200241, China.; Institute of Biosciences and Technology, Department of Molecular and Cellular Medicine, Texas A&M University Health Science Center, Houston, Texas 77030, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Oct 07; Vol. 6, pp. 34938. Date of Electronic Publication: 2016 Oct 07.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Energy Metabolism/*physiology
Receptor, Melanocortin, Type 3/*deficiency
Receptor, Melanocortin, Type 4/*deficiency
Adipose Tissue, White/pathology ; Animals ; Animals, Genetically Modified ; Body Weight ; Drinking ; Eating ; Energy Metabolism/genetics ; Female ; Gene Knockout Techniques ; Glucose/metabolism ; Homeostasis ; Kidney/pathology ; Lipids/blood ; Liver/pathology ; Male ; Rats ; Rats, Mutant Strains ; Rats, Sprague-Dawley ; Receptor, Melanocortin, Type 3/genetics ; Receptor, Melanocortin, Type 3/metabolism ; Receptor, Melanocortin, Type 4/genetics ; Receptor, Melanocortin, Type 4/metabolism

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Skocz do pozycji: 7.

Tytuł:: Activation of the brain melanocortin system is required for leptin-induced modulation of chemorespiratory function.
Autorzy:: Bassi M; Department of Physiology and Pathology, School of Dentistry, São Paulo State University (UNESP), Araraquara, Brazil.
Nakamura NB
Furuya WI
Colombari DS
Menani JV
do Carmo JM
da Silva AA
Hall JE
Colombari E; Pokaż więcej
Źródło:: Acta physiologica (Oxford, England) [Acta Physiol (Oxf)] 2015 Apr; Vol. 213 (4), pp. 893-901. Date of Electronic Publication: 2014 Sep 30.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Leptin/*pharmacology
Melanocortins/*metabolism
Melanocyte-Stimulating Hormones/*pharmacology
Receptor, Melanocortin, Type 3/*metabolism
Receptor, Melanocortin, Type 4/*metabolism
Respiratory Physiological Phenomena/*drug effects
Animals ; Body Weight/drug effects ; Carbon Dioxide/blood ; Gene Expression Regulation ; Hypercapnia/chemically induced ; Leptin/administration & dosage ; Male ; Melanocyte-Stimulating Hormones/administration & dosage ; Mice ; Mice, Knockout ; Rats ; Rats, Sprague-Dawley ; Receptor, Melanocortin, Type 3/genetics ; Receptor, Melanocortin, Type 4/genetics

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Skocz do pozycji: 8.

Tytuł:: Associations of the melanocortin 3 receptor C17A + G241A haplotype with body composition and inflammation in African-American adults.
Autorzy:: Demidowich AP; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.; Office of the Clinical Director, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Parikh VJ; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Dedhia N; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Branham RE; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Madi SA; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Marwitz SE; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Roberson RB; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Uhlman AJ; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Levi NJ; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Mi SJ; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Jun JY; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Broadney MM; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Brady SM; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.
Yanovski JA; Section on Growth and Obesity, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD, 20892.; Pokaż więcej
Źródło:: Annals of human genetics [Ann Hum Genet] 2019 Sep; Vol. 83 (5), pp. 355-360. Date of Electronic Publication: 2019 Apr 02.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms:: Adiposity/*genetics
Black or African American/*genetics
Inflammation/*genetics
Receptor, Melanocortin, Type 3/*genetics
Adult ; Body Mass Index ; Female ; Haplotypes ; Humans ; Male ; Young Adult

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Skocz do pozycji: 9.

Tytuł:: Melanocortin 3 receptor gene polymorphism is associated with polycystic ovary syndrome in Turkish population.
Autorzy:: Hepsen S; a Department of Endocrinology and Metabolism , University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.
Cakal E; a Department of Endocrinology and Metabolism , University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.
Karakose M; b Department of Endocrinology and Metabolism , Necmettin Erbakan University, Meram Medicine Faculty , Konya , Turkey.
Eyerci N; c Department of Medical Biology , Kafkas University , Kars , Turkey.
Saat H; d Department of Medical Genetic , University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.
Beysel S; e Department of Endocrinology and Metabolism , Eskisehir State Hospital , Eskisehir , Turkey.
Oztekin S; f Department of Internal Medicine , University of Health Sciences, Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.
Pinarli F; g Department of Medical Genetic , University of Health Sciences Diskapi Yildirim Beyazit Training and Research Hospital , Ankara , Turkey.
Parlak M; h Department of Pharmacology , Sivas Numune Hospital , Sivas , Turkey.; Pokaż więcej
Źródło:: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology [Gynecol Endocrinol] 2019 Aug; Vol. 35 (8), pp. 685-690. Date of Electronic Publication: 2019 Feb 20.
Typ publikacji:: Journal Article
MeSH Terms:: Polymorphism, Single Nucleotide*
Polycystic Ovary Syndrome/*genetics
Receptor, Melanocortin, Type 3/*genetics
Adolescent ; Adult ; Case-Control Studies ; Female ; Gene Frequency ; Genetic Association Studies ; Genetic Predisposition to Disease ; Genotype ; Humans ; Insulin Resistance/genetics ; Polycystic Ovary Syndrome/epidemiology ; Turkey/epidemiology ; Young Adult

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Skocz do pozycji: 10.

Tytuł:: Melanocortin-3 receptors are involved in adaptation to restricted feeding.
Autorzy:: Begriche K; Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA.
Marston OJ
Rossi J
Burke LK
McDonald P
Heisler LK
Butler AA; Pokaż więcej
Źródło:: Genes, brain, and behavior [Genes Brain Behav] 2012 Apr; Vol. 11 (3), pp. 291-302. Date of Electronic Publication: 2012 Feb 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Adaptation, Physiological*/genetics
Caloric Restriction*/adverse effects
Feeding Behavior/*physiology
Receptor, Melanocortin, Type 3/*physiology
Starvation/*metabolism
Animals ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptor, Melanocortin, Type 3/agonists ; Receptor, Melanocortin, Type 3/genetics ; Starvation/genetics ; Starvation/physiopathology

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Skocz do pozycji: 11.

Tytuł:: Melanocortin-3-receptor promoter polymorphism associated with tuberculosis susceptibility does not influence protein expression.
Autorzy:: Eggert M; Institute of Human Genetics, University Hospital, Ludwig-Maximilians-University Munich, Munich, Germany. />Pfob M
Steinlein OK; Pokaż więcej
Źródło:: BMC research notes [BMC Res Notes] 2013 Mar 15; Vol. 6, pp. 99. Date of Electronic Publication: 2013 Mar 15.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genetic Predisposition to Disease*
Polymorphism, Single Nucleotide*
Promoter Regions, Genetic*
Receptor, Melanocortin, Type 3/*genetics
Tuberculosis/*genetics
Humans ; Receptor, Melanocortin, Type 3/metabolism