Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Receptor, Serotonin, 5-HT1A"" wg kryterium: Temat


Tytuł :
Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors.
Autorzy :
Gorinski N; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Bijata M; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.; Cell Biophysics, Nencki Institute, Pasteur Str. 3, 02-093, Warsaw, Poland.
Prasad S; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Wirth A; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Abdel Galil D; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Zeug A; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Bazovkina D; Behavioural Neurogenomics, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia.
Kondaurova E; Behavioural Neurogenomics, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia.
Kulikova E; Behavioural Neurogenomics, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia.
Ilchibaeva T; Behavioural Neurogenomics, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia.
Zareba-Koziol M; Cell Biophysics, Nencki Institute, Pasteur Str. 3, 02-093, Warsaw, Poland.
Papaleo F; Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163, Genova, Italy.
Scheggia D; Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163, Genova, Italy.
Kochlamazashvili G; Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163, Genova, Italy.
Dityatev A; Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia, 16163, Genova, Italy.; Molecular Neuroplasticity, DZNE, Leipziger Str. 44, 39120, Magdeburg, Germany.
Smyth I; Anatomy & Developmental Biology, Monash University, 3800, Melbourne, Australia.
Krzystyniak A; Cell Biophysics, Nencki Institute, Pasteur Str. 3, 02-093, Warsaw, Poland.
Wlodarczyk J; Cell Biophysics, Nencki Institute, Pasteur Str. 3, 02-093, Warsaw, Poland.
Richter DW; Neuro and Sensory Physiology, University of Göttingen, 37073, Göttingen, Germany.
Strekalova T; Sechenov First Moscow State Medical University, Moscow, Russia.; Neuroscience, Maastricht University, 6229 ER, Maastricht, Netherlands.; Laboratory of Psychiatric Neurobiology and Institute of General Pathology and Pathophysiology, Sechenov First Moscow State Medical University, Trubetskaya 8, 119315, Moscow, Russia.
Sigrist S; Institute of Biology, Free University Berlin, Takustr. 6, 14195, Berlin, Germany.
Bang C; Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Hobuß L; Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Fiedler J; Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Thum T; Institute of Molecular and Translational Therapeutic Strategies, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Naumenko VS; Behavioural Neurogenomics, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia. .
Pandey G; Department of Psychiatry, University of Illinois, 1601 W. Taylor Street, Chicago, IL, 60612, USA. .
Ponimaskin E; Cellular Neurophysiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany. .
Pokaż więcej
Źródło :
Nature Communications [Nat Commun] 2019 Sep 02; Vol. 10 (1), pp. 3924. Date of Electronic Publication: 2019 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
MeSH Terms :
Brain/*physiopathology
Depression/*physiopathology
Depressive Disorder, Major/*physiopathology
Receptor, Serotonin, 5-HT1A/*metabolism
Acyltransferases/genetics ; Acyltransferases/metabolism ; Animals ; Brain/metabolism ; Cell Line, Tumor ; Depression/genetics ; Depression/metabolism ; Depressive Disorder, Major/genetics ; Gene Expression Regulation ; Humans ; Lipoylation ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Rats, Wistar ; Receptor, Serotonin, 5-HT1A/genetics
Czasopismo naukowe
Tytuł :
Piperine-mediated suppression of voltage-dependent Ca2+ influx and glutamate release in rat hippocampal nerve terminals involves 5HT1A receptors and G protein βγ activation.
Autorzy :
Hsieh TY; P.H.D. Program in Nutrition & Food Science, Fu Jen Catholic University, New Taipei City, Taiwan.
Chang Y
Wang SJ
Pokaż więcej
Źródło :
Food & Function [Food Funct] 2019 May 22; Vol. 10 (5), pp. 2720-2728.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101549033 Publication Model: Print Cited Medium: Internet ISSN: 2042-650X (Electronic) Linking ISSN: 20426496 NLM ISO Abbreviation: Food Funct Subsets: MEDLINE
MeSH Terms :
Alkaloids/*pharmacology
Benzodioxoles/*pharmacology
Calcium/*metabolism
GTP-Binding Protein beta Subunits/*metabolism
GTP-Binding Protein gamma Subunits/*metabolism
Glutamic Acid/*metabolism
Hippocampus/*metabolism
Piperidines/*pharmacology
Polyunsaturated Alkamides/*pharmacology
Receptor, Serotonin, 5-HT1A/*metabolism
4-Aminopyridine/metabolism ; Animals ; Calcium Channels/genetics ; Calcium Channels/metabolism ; GTP-Binding Protein beta Subunits/genetics ; GTP-Binding Protein gamma Subunits/genetics ; Hippocampus/drug effects ; Male ; Piper nigrum/chemistry ; Presynaptic Terminals/drug effects ; Presynaptic Terminals/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptor, Serotonin, 5-HT1A/genetics ; Synaptosomes/drug effects ; Synaptosomes/metabolism
Czasopismo naukowe
Tytuł :
Characteristics of metabolic stability and the cell permeability of 2-pyrimidinyl-piperazinyl-alkyl derivatives of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione with antidepressant- and anxiolytic-like activities.
Autorzy :
Zagórska A; Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Partyka A; Department of Clinical Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Bucki A; Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Kołaczkowski M; Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Jastrzębska-Więsek M; Department of Clinical Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Czopek A; Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Siwek A; Department of Pharmacobiology, Jagiellonian University Medical College, Kraków, Poland.
Głuch-Lutwin M; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
Bednarski M; Department of Pharmacodynamics, Jagiellonian University Medical College, Kraków, Poland.
Bajda M; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Kraków, Poland.
Jończyk J; Department of Physicochemical Drug Analysis, Jagiellonian University Medical College, Kraków, Poland.
Piska K; Department of Pharmaceutical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Koczurkiewicz P; Department of Pharmaceutical Biochemistry, Jagiellonian University Medical College, Kraków, Poland.
Wesołowska A; Department of Clinical Pharmacy, Jagiellonian University Medical College, Kraków, Poland.
Pawłowski M; Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland.
Pokaż więcej
Źródło :
Chemical Biology & Drug Design [Chem Biol Drug Des] 2019 Apr; Vol. 93 (4), pp. 511-521. Date of Electronic Publication: 2018 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101262549 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1747-0285 (Electronic) Linking ISSN: 17470277 NLM ISO Abbreviation: Chem Biol Drug Des Subsets: MEDLINE
MeSH Terms :
Anti-Anxiety Agents/*chemistry
Antidepressive Agents/*chemistry
Purines/*chemistry
Receptor, Serotonin, 5-HT1A/*chemistry
Animals ; Anti-Anxiety Agents/metabolism ; Anti-Anxiety Agents/pharmacology ; Antidepressive Agents/metabolism ; Antidepressive Agents/pharmacology ; Binding Sites ; Imidazoles/chemistry ; Maze Learning/drug effects ; Mice ; Microsomes, Liver/drug effects ; Microsomes, Liver/metabolism ; Molecular Dynamics Simulation ; Permeability/drug effects ; Phosphoric Diester Hydrolases/chemistry ; Phosphoric Diester Hydrolases/metabolism ; Piperazine/chemistry ; Protein Binding ; Protein Structure, Tertiary ; Purines/metabolism ; Purines/pharmacology ; Pyrimidines/chemistry ; Receptor, Serotonin, 5-HT1A/metabolism ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Loss of Adult 5-HT1A Autoreceptors Results in a Paradoxical Anxiogenic Response to Antidepressant Treatment.
Autorzy :
Turcotte-Cardin V; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Vahid-Ansari F; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Luckhart C; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Daigle M; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.
Geddes SD; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Tanaka KF; Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, 160-8582, Japan.
Hen R; New York State Psychiatric Institute and Department of Psychiatry, Columbia University, New York, New York 10032, and.
James J; Royal's Institute of Mental Health, University of Ottawa, Ottawa, Ontario, K1Z 7K4 Canada.
Merali Z; Royal's Institute of Mental Health, University of Ottawa, Ottawa, Ontario, K1Z 7K4 Canada.
Béïque JC; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Albert PR; Ottawa Hospital Research Institute (Neuroscience), University of Ottawa, Ottawa, Ontario K1H 8M5, Canada, .; Department of Cellular and Molecular Medicine, University of Ottawa Brain and Mind Research Institute, Ottawa, Ontario K1H 8M5, Canada.
Pokaż więcej
Źródło :
The Journal Of Neuroscience: The Official Journal Of The Society For Neuroscience [J Neurosci] 2019 Feb 20; Vol. 39 (8), pp. 1334-1346. Date of Electronic Publication: 2018 Dec 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J. Neurosci. Subsets: MEDLINE
MeSH Terms :
Antidepressive Agents/*adverse effects
Anxiety/*chemically induced
Autoreceptors/*drug effects
Receptor, Serotonin, 5-HT1A/*deficiency
Serotonergic Neurons/*drug effects
Serotonin Uptake Inhibitors/*adverse effects
8-Hydroxy-2-(di-n-propylamino)tetralin/toxicity ; Animals ; Antidepressive Agents/pharmacology ; Brain Chemistry/drug effects ; Exploratory Behavior/drug effects ; Feeding Behavior/drug effects ; Female ; Fluoxetine/adverse effects ; Fluoxetine/pharmacology ; Hypothermia/chemically induced ; Hypothermia/physiopathology ; Male ; Maze Learning/drug effects ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Nerve Net/drug effects ; Proto-Oncogene Proteins c-fos/analysis ; Receptor, Serotonin, 5-HT1A/drug effects ; Receptor, Serotonin, 5-HT1A/physiology ; Serotonergic Neurons/physiology ; Serotonin/metabolism ; Serotonin Uptake Inhibitors/pharmacology ; Swimming
Czasopismo naukowe
Tytuł :
Repeated administration of methylphenidate produces reinforcement and downregulates 5-HT-1A receptor expression in the nucleus accumbens.
Autorzy :
Salman T; Neuroscience Research Laboratory, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. Electronic address: .
Nawaz S; Neuroscience Research Laboratory, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Waraich RS; Pathobiochemistry and Molecular Physiology Laboratory, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Haleem DJ; Neuroscience Research Laboratory, Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan. Electronic address: .
Pokaż więcej
Źródło :
Life Sciences [Life Sci] 2019 Feb 01; Vol. 218, pp. 139-146. Date of Electronic Publication: 2018 Dec 27.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0631 (Electronic) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci. Subsets: MEDLINE
MeSH Terms :
Central Nervous System Stimulants/*pharmacology
Maze Learning/*drug effects
Memory/*drug effects
Methylphenidate/*pharmacology
Nucleus Accumbens/*metabolism
Prefrontal Cortex/*metabolism
Receptor, Serotonin, 5-HT1A/*metabolism
Animals ; Central Nervous System Stimulants/administration & dosage ; Down-Regulation ; Male ; Methylphenidate/administration & dosage ; Nucleus Accumbens/drug effects ; Prefrontal Cortex/drug effects ; Rats ; Receptor, Serotonin, 5-HT1A/chemistry ; Receptor, Serotonin, 5-HT1A/genetics
Czasopismo naukowe
Tytuł :
[Hypersexuality Induced by Aripiprazole].
Transliterated Title :
Sexuelle Enthemmung bei Therapie mit Aripiprazol.
Autorzy :
Kozian R; Vinzenz von Paul Hospital, Rottweil.
Pokaż więcej
Źródło :
Psychiatrische Praxis [Psychiatr Prax] 2020 Jan; Vol. 47 (1), pp. 43-45. Date of Electronic Publication: 2019 Jul 08.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Georg Thieme Verlag Country of Publication: Germany NLM ID: 0423204 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0876 (Electronic) Linking ISSN: 03034259 NLM ISO Abbreviation: Psychiatr Prax Subsets: MEDLINE
MeSH Terms :
Antipsychotic Agents*/adverse effects
Antipsychotic Agents*/therapeutic use
Aripiprazole*/adverse effects
Aripiprazole*/therapeutic use
Sexual Behavior*
Sexual Dysfunctions, Psychological/*chemically induced
Germany ; Humans ; Receptor, Serotonin, 5-HT1A ; Receptor, Serotonin, 5-HT2A ; Serotonin 5-HT2 Receptor Antagonists ; Sexual Dysfunctions, Psychological/psychology
Czasopismo naukowe
Tytuł :
Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression.
Autorzy :
Kautzky A; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
James GM; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Philippe C; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Austria.
Baldinger-Melich P; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Kraus C; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Kranz GS; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Vanicek T; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Gryglewski G; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Hartmann AM; University Clinic for Psychiatry, Psychotherapy and Psychosomatic, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Hahn A; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Wadsak W; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Austria.; Center for Biomarker Research in Medicine (CBmed), Graz, Austria.
Mitterhauser M; Division of Nuclear Medicine, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Wien, Austria.; Ludwig Boltzmann Institute Applied Diagnostics, Vienna, Austria.
Rujescu D; University Clinic for Psychiatry, Psychotherapy and Psychosomatic, Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Kasper S; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria.
Lanzenberger R; Department of Psychiatry and Psychotherapy, Medical University of Vienna, Wien, Austria. .
Pokaż więcej
Źródło :
Translational Psychiatry [Transl Psychiatry] 2019 Jan 16; Vol. 9 (1), pp. 5. Date of Electronic Publication: 2019 Jan 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
MeSH Terms :
Epistasis, Genetic*
Brain/*metabolism
Brain-Derived Neurotrophic Factor/*metabolism
Depressive Disorder/*genetics
Receptor, Serotonin, 5-HT1A/*metabolism
Adult ; Alleles ; Brain/diagnostic imaging ; Brain-Derived Neurotrophic Factor/genetics ; Cross-Sectional Studies ; Female ; Genotype ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Piperazines/metabolism ; Polymorphism, Single Nucleotide ; Positron-Emission Tomography ; Pyridines/metabolism ; Receptor, Serotonin, 5-HT1A/genetics
Czasopismo naukowe
Tytuł :
Depletion of apomorphine induced behavioral sensitization in rats treated with escitalopram.
Autorzy :
Farhan M; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, Pakistan.
Parveen M; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, Pakistan.
Pokaż więcej
Źródło :
Pakistan Journal Of Pharmaceutical Sciences [Pak J Pharm Sci] 2019 Jan; Vol. 32 (1), pp. 197-203.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Faculty of Pharmacy, University of Karachi Country of Publication: Pakistan NLM ID: 9426356 Publication Model: Print Cited Medium: Print ISSN: 1011-601X (Print) Linking ISSN: 1011601X NLM ISO Abbreviation: Pak J Pharm Sci Subsets: MEDLINE
MeSH Terms :
Apomorphine/*pharmacology
Behavior, Animal/*drug effects
Brain/*drug effects
Central Nervous System Sensitization/*drug effects
Citalopram/*pharmacology
Receptor, Serotonin, 5-HT1A/*drug effects
Serotonin 5-HT1 Receptor Agonists/*pharmacology
Serotonin Uptake Inhibitors/*pharmacology
Animals ; Brain/metabolism ; Exploratory Behavior/drug effects ; Male ; Motor Activity/drug effects ; Rats, Wistar ; Receptor, Serotonin, 5-HT1A/metabolism ; Time Factors
Czasopismo naukowe
Tytuł :
5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox.
Autorzy :
Tran HQ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Shin EJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Hoai Nguyen BC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Phan DH; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Kang MJ; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea.
Jang CG; Department of Pharmacology, School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
Jeong JH; Department of Pharmacology, College of Medicine, Chung-Ang University, Seoul, 06974, Republic of Korea.
Nah SY; Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul, 05029, Republic of Korea.
Mouri A; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Aichi, 470-1192, Japan.
Saito K; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Aichi, 470-1192, Japan.
Nabeshima T; Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Aichi, 470-1192, Japan; Aino University, Ibaraki, 576-0012, Japan; Japanese Drug Organization of Appropriate and Research, Nagoya, 468-0069, Japan.
Kim HC; Neuropsychopharmacology and Toxicology Program, College of Pharmacy, Kangwon National University, Chunchon, 24341, Republic of Korea. Electronic address: .
Pokaż więcej
Źródło :
Food And Chemical Toxicology: An International Journal Published For The British Industrial Biological Research Association [Food Chem Toxicol] 2019 Jan; Vol. 123, pp. 125-141. Date of Electronic Publication: 2018 Oct 24.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8207483 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6351 (Electronic) Linking ISSN: 02786915 NLM ISO Abbreviation: Food Chem. Toxicol. Subsets: MEDLINE
MeSH Terms :
NADPH Oxidases/*metabolism
Protein Kinase C-delta/*metabolism
Receptor, Serotonin, 5-HT1A/*metabolism
Serotonin/*metabolism
Serotonin 5-HT1 Receptor Agonists/*administration & dosage
Serotonin Syndrome/*drug therapy
8-Hydroxy-2-(di-n-propylamino)tetralin ; Animals ; Behavior, Animal/drug effects ; Hypothalamus/drug effects ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; NADPH Oxidases/genetics ; Phosphorylation/drug effects ; Protein Binding ; Protein Kinase C-delta/genetics ; Receptor, Serotonin, 5-HT1A/genetics ; Serotonin Syndrome/genetics ; Serotonin Syndrome/metabolism ; Serotonin Syndrome/psychology
Czasopismo naukowe
Tytuł :
Altered Global mRNA Expressions of Pain and Aggression Related Genes in the Blood of Children with Autism Spectrum Disorders.
Autorzy :
Sener EF; Department of Medical Biology, Erciyes University Medical Faculty , 38039, Kayseri, Turkey. .; Erciyes University Genome and Stem Cell Center (GENKOK), 38039, Kayseri, Turkey. .
Taheri S; Department of Medical Biology, Erciyes University Medical Faculty , 38039, Kayseri, Turkey.; Erciyes University Genome and Stem Cell Center (GENKOK), 38039, Kayseri, Turkey.
Sahin MC; Van Ozalp Education and Research Hospital, Van, Turkey.
Bayramov KK; Erciyes University Genome and Stem Cell Center (GENKOK), 38039, Kayseri, Turkey.
Marasli MK; Ordu Education and Research Hospital, Ordu, Turkey.
Zararsiz G; Department of Biostatistics, Erciyes University Medical Faculty , 38039, Kayseri, Turkey.
Mehmetbeyoglu E; Department of Medical Biology, Erciyes University Medical Faculty , 38039, Kayseri, Turkey.; Erciyes University Genome and Stem Cell Center (GENKOK), 38039, Kayseri, Turkey.
Oztop DB; Department of Child and Adolescent Psychiatry, Ankara University Medical Faculty , Ankara, Turkey.
Canpolat M; Department of Child Neurology, Erciyes University Medical Faculty, 38039, Kayseri, Turkey.
Canatan H; Department of Medical Biology, Erciyes University Medical Faculty , 38039, Kayseri, Turkey.
Ozkul Y; Department of Medical Genetics, Erciyes University Medical Faculty, 38039, Kayseri, Turkey.
Pokaż więcej
Źródło :
Journal Of Molecular Neuroscience: MN [J Mol Neurosci] 2019 Jan; Vol. 67 (1), pp. 89-96. Date of Electronic Publication: 2018 Dec 05.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Humana Press Country of Publication: United States NLM ID: 9002991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1166 (Electronic) Linking ISSN: 08958696 NLM ISO Abbreviation: J. Mol. Neurosci. Subsets: MEDLINE
MeSH Terms :
Autism Spectrum Disorder/*genetics
NAV1.7 Voltage-Gated Sodium Channel/*genetics
RNA, Messenger/*blood
Receptor, Serotonin, 5-HT1A/*genetics
Receptors, Dopamine D4/*genetics
Receptors, Opioid/*genetics
Aggression ; Autism Spectrum Disorder/blood ; Autism Spectrum Disorder/physiopathology ; Biomarkers/blood ; Child, Preschool ; Cyclic GMP-Dependent Protein Kinase Type I/genetics ; Cyclic GMP-Dependent Protein Kinase Type I/metabolism ; Female ; Humans ; Male ; NAV1.7 Voltage-Gated Sodium Channel/metabolism ; Pain Perception ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptors, Dopamine D4/metabolism ; Receptors, Opioid/metabolism
Czasopismo naukowe
Tytuł :
Characterization and functional analyses of the human HTR1A gene: 5' regulatory region modulates gene expression in vitro.
Autorzy :
Wu X; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China.
Xu FL; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China.
Ding M; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China.
Zhang JJ; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China.
Yao J; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China. .
Wang BJ; School of Forensic Medicine, China Medical University, No. 77 Puhe Road, Shenbei New District, Shenyang, 110122, China. .
Pokaż więcej
Źródło :
BMC Genetics [BMC Genet] 2018 Dec 29; Vol. 19 (1), pp. 115. Date of Electronic Publication: 2018 Dec 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: BioMed Central Country of Publication: England NLM ID: 100966978 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2156 (Electronic) Linking ISSN: 14712156 NLM ISO Abbreviation: BMC Genet.
MeSH Terms :
Receptor, Serotonin, 5-HT1A/*genetics
5' Untranslated Regions ; Cell Line, Tumor ; Gene Expression Regulation ; Genes, Reporter ; HEK293 Cells ; Humans ; Receptor, Serotonin, 5-HT1A/metabolism ; Regulatory Elements, Transcriptional ; Schizophrenia/genetics ; Schizophrenia/pathology ; Sequence Deletion ; Transcription Factors/chemistry ; Transcription Factors/metabolism ; Transfection
Czasopismo naukowe
Tytuł :
Constrained dynamics of the sole tryptophan in the third intracellular loop of the serotonin1A receptor.
Autorzy :
Pal S; Academy of Scientific and Innovative Research, India; CSIR-Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500 007, India.
Aute R; CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Sarkar P; CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Bose S; CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Deshmukh MV; CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India.
Chattopadhyay A; CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India; Academy of Scientific and Innovative Research, India. Electronic address: .
Pokaż więcej
Źródło :
Biophysical Chemistry [Biophys Chem] 2018 Sep; Vol. 240, pp. 34-41. Date of Electronic Publication: 2018 Jun 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 0403171 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4200 (Electronic) Linking ISSN: 03014622 NLM ISO Abbreviation: Biophys. Chem. Subsets: MEDLINE
MeSH Terms :
Receptor, Serotonin, 5-HT1A/*chemistry
Tryptophan/*chemistry
Amino Acid Sequence ; Circular Dichroism ; Fluorescence Polarization ; Humans ; Protein Denaturation ; Protein Domains ; Protein Structure, Secondary ; Receptor, Serotonin, 5-HT1A/genetics ; Receptor, Serotonin, 5-HT1A/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/chemistry ; Recombinant Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
The serotonin hallucinogen 5-MeO-DMT alters cortico-thalamic activity in freely moving mice: Regionally-selective involvement of 5-HT1A and 5-HT2A receptors.
Autorzy :
Riga MS; Department of Neurochemistry and Neuropharmacology, Institut d'Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Spain; CIBERSAM (Centro de Investigación Biomédica en Red de Salud Mental), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain.
Lladó-Pelfort L; Department of Neurochemistry and Neuropharmacology, Institut d'Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Spain; CIBERSAM (Centro de Investigación Biomédica en Red de Salud Mental), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain.
Artigas F; Department of Neurochemistry and Neuropharmacology, Institut d'Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Spain; CIBERSAM (Centro de Investigación Biomédica en Red de Salud Mental), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain.
Celada P; Department of Neurochemistry and Neuropharmacology, Institut d'Investigacions Biomèdiques de Barcelona, CSIC-IDIBAPS, Spain; CIBERSAM (Centro de Investigación Biomédica en Red de Salud Mental), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Spain. Electronic address: .
Pokaż więcej
Źródło :
Neuropharmacology [Neuropharmacology] 2018 Nov; Vol. 142, pp. 219-230. Date of Electronic Publication: 2017 Dec 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE
MeSH Terms :
Hallucinogens/*pharmacology
Methoxydimethyltryptamines/*pharmacology
Prefrontal Cortex/*drug effects
Receptor, Serotonin, 5-HT1A/*metabolism
Receptor, Serotonin, 5-HT2A/*metabolism
Serotonin Receptor Agonists/*pharmacology
Thalamus/*drug effects
Visual Cortex/*drug effects
Animals ; Brain Waves/drug effects ; Brain Waves/physiology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Piperazines/pharmacology ; Prefrontal Cortex/metabolism ; Pyridines/pharmacology ; Receptor, Serotonin, 5-HT1A/genetics ; Receptor, Serotonin, 5-HT2A/genetics ; Serotonin Antagonists/pharmacology ; Thalamus/metabolism ; Visual Cortex/metabolism
Czasopismo naukowe
Tytuł :
Role of hippocampal 5-HT1A receptors in the antidepressant-like phenotype of mice expressing RGS-insensitive Gαi2 protein.
Autorzy :
Senese NB; Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, MI, 48109, USA.
Oginsky M; Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, MI, 48109, USA.
Neubig RR; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI, 48823, USA.
Ferrario C; Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, MI, 48109, USA.
Jutkiewicz EM; Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, MI, 48109, USA.
Traynor JR; Department of Pharmacology and Edward F Domino Research Center, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: .
Pokaż więcej
Źródło :
Neuropharmacology [Neuropharmacology] 2018 Oct; Vol. 141, pp. 296-304. Date of Electronic Publication: 2018 Sep 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
Journal Info :
Publisher: Pergamon Press Country of Publication: England NLM ID: 0236217 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7064 (Electronic) Linking ISSN: 00283908 NLM ISO Abbreviation: Neuropharmacology Subsets: MEDLINE
MeSH Terms :
GTP-Binding Protein alpha Subunit, Gi2/*metabolism
Hippocampus/*metabolism
Immobility Response, Tonic/*physiology
RGS Proteins/*antagonists & inhibitors
Receptor, Serotonin, 5-HT1A/*physiology
8-Hydroxy-2-(di-n-propylamino)tetralin/antagonists & inhibitors ; 8-Hydroxy-2-(di-n-propylamino)tetralin/pharmacology ; Animals ; CA1 Region, Hippocampal/drug effects ; CA1 Region, Hippocampal/metabolism ; Female ; GTP-Binding Protein alpha Subunit, Gi2/genetics ; Gene Knock-In Techniques ; Hippocampus/drug effects ; Male ; Mice ; Microinjections ; Phenotype ; Piperazines/pharmacology ; Pyramidal Cells/physiology ; Pyridines/pharmacology ; Receptor, Serotonin, 5-HT1A/biosynthesis ; Serotonin 5-HT1 Receptor Agonists/pharmacology ; Serotonin 5-HT1 Receptor Antagonists/pharmacology
Czasopismo naukowe
Tytuł :
A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression.
Autorzy :
Le François B; Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, Ph.D. Programs in Biochemistry and Biology, City University of New York, New York, New York, 10031.; Department of Cellular and Molecular Medicine, UOttawa Brain and Mind Research Institute, Ottawa Hospital Research Institute (Neuroscience), Ottawa, Ontario K1H 8M5, Canada, and.
Zhang L; Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, Ph.D. Programs in Biochemistry and Biology, City University of New York, New York, New York, 10031.
Mahajan GJ; Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39216.
Stockmeier CA; Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39216.
Friedman E; Department of Molecular, Cellular & Biomedical Sciences, CUNY School of Medicine, Ph.D. Programs in Biochemistry and Biology, City University of New York, New York, New York, 10031.
Albert PR; Department of Cellular and Molecular Medicine, UOttawa Brain and Mind Research Institute, Ottawa Hospital Research Institute (Neuroscience), Ottawa, Ontario K1H 8M5, Canada, and .
Pokaż więcej
Źródło :
The Journal Of Neuroscience: The Official Journal Of The Society For Neuroscience [J Neurosci] 2018 Sep 19; Vol. 38 (38), pp. 8200-8210. Date of Electronic Publication: 2018 Aug 07.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info :
Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J. Neurosci. Subsets: MEDLINE
MeSH Terms :
Alternative Splicing*
Depressive Disorder, Major/*metabolism
Hippocampus/*metabolism
Mesencephalon/*metabolism
RNA Stability/*physiology
Receptor, Serotonin, 5-HT1A/*metabolism
Adult ; Depressive Disorder, Major/genetics ; Female ; HEK293 Cells ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; Humans ; Male ; Middle Aged ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Polypyrimidine Tract-Binding Protein/genetics ; Polypyrimidine Tract-Binding Protein/metabolism ; Receptor, Serotonin, 5-HT1A/genetics
Czasopismo naukowe
Tytuł :
5-HT1A receptor ligands and their therapeutic applications: review of new patents.
Autorzy :
Staroń J; a Institute of Pharmacology, Polish Academy of Sciences , Kraków , Poland.
Bugno R; a Institute of Pharmacology, Polish Academy of Sciences , Kraków , Poland.
Hogendorf AS; a Institute of Pharmacology, Polish Academy of Sciences , Kraków , Poland.
Bojarski AJ; a Institute of Pharmacology, Polish Academy of Sciences , Kraków , Poland.
Pokaż więcej
Źródło :
Expert Opinion On Therapeutic Patents [Expert Opin Ther Pat] 2018 Sep; Vol. 28 (9), pp. 679-689. Date of Electronic Publication: 2018 Sep 07.
Typ publikacji :
Journal Article; Review
Journal Info :
Publisher: Informa Healthcare Country of Publication: England NLM ID: 9516419 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7674 (Electronic) Linking ISSN: 13543776 NLM ISO Abbreviation: Expert Opin Ther Pat Subsets: MEDLINE
MeSH Terms :
Receptor, Serotonin, 5-HT1A/*drug effects
Serotonin 5-HT1 Receptor Agonists/*pharmacology
Serotonin 5-HT1 Receptor Antagonists/*pharmacology
Animals ; Drug Design ; Humans ; Ligands ; Patents as Topic ; Receptor, Serotonin, 5-HT1A/metabolism
Czasopismo naukowe
Tytuł :
Long-Term Effects of Iloperidone on Cerebral Serotonin and Adrenoceptor Subtypes.
Autorzy :
Choi YK; Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, MA, USA.; Mailman Research Center, McLean Hospital, Belmont, MA, USA.
Tarazi FI; Department of Psychiatry and Neuroscience Program, Harvard Medical School, Boston, MA, USA. .; Mailman Research Center, McLean Hospital, Belmont, MA, USA. .
Pokaż więcej
Źródło :
Journal Of Molecular Neuroscience: MN [J Mol Neurosci] 2018 Sep; Vol. 66 (1), pp. 59-67. Date of Electronic Publication: 2018 Aug 09.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Humana Press Country of Publication: United States NLM ID: 9002991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1166 (Electronic) Linking ISSN: 08958696 NLM ISO Abbreviation: J. Mol. Neurosci. Subsets: MEDLINE
MeSH Terms :
Antipsychotic Agents/*pharmacology
Cerebral Cortex/*drug effects
Isoxazoles/*pharmacology
Piperidines/*pharmacology
Receptor, Serotonin, 5-HT1A/*genetics
Receptor, Serotonin, 5-HT2A/*genetics
Receptors, Adrenergic, alpha/*genetics
Animals ; Basal Ganglia/drug effects ; Basal Ganglia/metabolism ; Cerebral Cortex/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Male ; Rats ; Rats, Sprague-Dawley ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptor, Serotonin, 5-HT2A/metabolism ; Receptors, Adrenergic, alpha/metabolism
Czasopismo naukowe
Tytuł :
Synthesis of new 5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT1A receptor ligands.
Autorzy :
Ślifirski G; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland.
Król M; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland. Electronic address: .
Kleps J; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland.
Podsadni P; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland.
Belka M; Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 107, J. Hallera Street, 80-416, Gdańsk, Poland.
Bączek T; Department of Pharmaceutical Chemistry, Medical University of Gdańsk, 107, J. Hallera Street, 80-416, Gdańsk, Poland.
Siwek A; Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343, Kraków, Poland.
Stachowicz K; Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343, Kraków, Poland.
Szewczyk B; Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343, Kraków, Poland.
Nowak G; Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343, Kraków, Poland; Chair of Pharmacobiology, Jagiellonian University Medical College, 9, Medyczna Street, 30-688, Kraków, Poland.
Bojarski A; Institute of Pharmacology, Polish Academy of Sciences, 12, Smętna Street, 31-343, Kraków, Poland.
Kozioł AE; Faculty of Chemistry, Maria Curie-Skłodowska University, 3, M. Curie-Skłodowskiej Sq., 20-031, Lublin, Poland.
Turło J; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland.
Herold F; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, 1, Banacha Street, 02-097, Warszawa, Poland.
Pokaż więcej
Źródło :
European Journal Of Medicinal Chemistry [Eur J Med Chem] 2019 Oct 15; Vol. 180, pp. 383-397. Date of Electronic Publication: 2019 Jul 12.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
MeSH Terms :
Pyrimidines/*pharmacology
RNA-Binding Proteins/*antagonists & inhibitors
Receptor, Serotonin, 5-HT1A/*metabolism
Tryptamines/*pharmacology
Animals ; Cells, Cultured ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; HEK293 Cells ; Humans ; Ligands ; Male ; Mice ; Models, Molecular ; Molecular Structure ; Pyrimidines/chemical synthesis ; Pyrimidines/chemistry ; RNA-Binding Proteins/metabolism ; Rats ; Structure-Activity Relationship ; Tryptamines/chemistry
Czasopismo naukowe
Tytuł :
Effects of postnatal handling on adult behavior and brain mRNA expression of serotonin receptor, brain-derived neurotrophic factor and GABA-A receptor subunit.
Autorzy :
Li H; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Japan.
Ishikawa C; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Japan.
Shiga T; Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Japan; Department of Neurobiology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, 305-8577, Japan. Electronic address: .
Pokaż więcej
Źródło :
International Journal Of Developmental Neuroscience: The Official Journal Of The International Society For Developmental Neuroscience [Int J Dev Neurosci] 2018 Aug; Vol. 68, pp. 17-25. Date of Electronic Publication: 2018 Apr 17.
Typ publikacji :
Journal Article
Journal Info :
Publisher: Elsevier Science Country of Publication: United States NLM ID: 8401784 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-474X (Electronic) Linking ISSN: 07365748 NLM ISO Abbreviation: Int. J. Dev. Neurosci.
MeSH Terms :
Handling, Psychological*
Brain/*metabolism
Brain-Derived Neurotrophic Factor/*genetics
RNA, Messenger/*metabolism
Receptor, Serotonin, 5-HT1A/*genetics
Receptors, GABA-A/*genetics
Animals ; Animals, Newborn ; Brain/growth & development ; Brain-Derived Neurotrophic Factor/metabolism ; Female ; Maternal Behavior ; Maze Learning/physiology ; Mice ; Mice, Inbred BALB C ; Pregnancy ; Receptor, Serotonin, 5-HT1A/metabolism ; Receptors, GABA-A/metabolism ; Swimming
Czasopismo naukowe
Tytuł :
Serotonin-1A receptor dependent modulation of pain and reward for improving therapy of chronic pain.
Autorzy :
Haleem DJ; Neuroscience Research Laboratory, Dr Panjwani Center for Molecular Medicine & Drug Research (PCMD), International Center for Chemical and Biological Science (ICCBS), University of Karachi, Karachi 75270, Pakistan. Electronic address: .
Pokaż więcej
Źródło :
Pharmacological Research [Pharmacol Res] 2018 Aug; Vol. 134, pp. 212-219. Date of Electronic Publication: 2018 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
Journal Info :
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8907422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-1186 (Electronic) Linking ISSN: 10436618 NLM ISO Abbreviation: Pharmacol. Res. Subsets: MEDLINE
MeSH Terms :
Reward*
Analgesics/*therapeutic use
Brain/*drug effects
Chronic Pain/*drug therapy
Pain Perception/*drug effects
Pain Threshold/*drug effects
Receptor, Serotonin, 5-HT1A/*drug effects
Serotonin 5-HT1 Receptor Agonists/*therapeutic use
Analgesics/adverse effects ; Analgesics, Opioid/adverse effects ; Animals ; Brain/metabolism ; Brain/physiopathology ; Chronic Pain/metabolism ; Chronic Pain/physiopathology ; Chronic Pain/psychology ; Dopamine/metabolism ; Humans ; Opioid-Related Disorders/metabolism ; Opioid-Related Disorders/physiopathology ; Opioid-Related Disorders/psychology ; Receptor, Serotonin, 5-HT1A/metabolism ; Serotonin 5-HT1 Receptor Agonists/adverse effects ; Signal Transduction/drug effects
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies