Temat: "Receptor Activity-Modifying Proteins" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Pharmacological characterisation of mouse calcitonin and calcitonin receptor-like receptors reveals differences compared with human receptors.
Autorzy:: Garelja ML; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Bower RL; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Brimble MA; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Chand S; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Harris PWR; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Jamaluddin MA; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Petersen J; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Siow A; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Walker CS; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Hay DL; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Feb; Vol. 179 (3), pp. 416-434. Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Migraine Disorders*
Peptide Hormones*
Adrenomedullin/metabolism ; Adrenomedullin/pharmacology ; Animals ; Calcitonin/metabolism ; Calcitonin/pharmacology ; Calcitonin Gene-Related Peptide/metabolism ; Calcitonin Receptor-Like Protein/chemistry ; Humans ; Ligands ; Mice ; Rats ; Receptor Activity-Modifying Protein 1/metabolism ; Receptor Activity-Modifying Proteins/metabolism ; Receptors, Adrenomedullin ; Receptors, Calcitonin/chemistry

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Skocz do pozycji: 2.

Tytuł:: A selective role for receptor activity-modifying proteins in subchronic action of the amylin selective receptor agonist NN1213 compared with salmon calcitonin on body weight and food intake in male mice.
Autorzy:: Arrigoni S; Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.
Le Foll C; Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.
Cabak A; Global Research, Novo Nordisk AS, Måløv, Denmark.
Lundh S; Global Research, Novo Nordisk AS, Måløv, Denmark.
Raun K; Global Research, Novo Nordisk AS, Måløv, Denmark.
John LM; Global Research, Novo Nordisk AS, Måløv, Denmark.
Lutz TA; Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2021 Aug; Vol. 54 (3), pp. 4863-4876. Date of Electronic Publication: 2021 Jul 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Amylin Receptor Agonists*/pharmacology
Islet Amyloid Polypeptide*
Animals ; Body Weight ; Calcitonin ; Eating ; Male ; Mice ; Rats ; Receptor Activity-Modifying Protein 1 ; Receptor Activity-Modifying Protein 3 ; Receptor Activity-Modifying Proteins ; Receptors, Calcitonin

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Skocz do pozycji: 3.

Tytuł:: Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor.
Autorzy:: Kleinau G; Group Protein X-ray Crystallography and Signal Transduction, Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, D-10117 Berlin, Germany.
Heyder NA; Group Protein X-ray Crystallography and Signal Transduction, Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, D-10117 Berlin, Germany.
Tao YX; Department of Anatomy, Physiology and Pharmacology, Auburn University College of Veterinary Medicine, Auburn, AL 36849, USA.
Scheerer P; Group Protein X-ray Crystallography and Signal Transduction, Institute of Medical Physics and Biophysics, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, D-10117 Berlin, Germany.; German Centre for Cardiovascular Research (DZHK), Partner Site Berlin, D-10785 Berlin, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 10; Vol. 21 (16). Date of Electronic Publication: 2020 Aug 10.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Receptor, Melanocortin, Type 4/*chemistry
Receptor, Melanocortin, Type 4/*metabolism
Signal Transduction/*genetics
Agouti-Related Protein/chemistry ; Agouti-Related Protein/pharmacology ; Amino Acid Sequence ; Animals ; Arrestins/metabolism ; Binding Sites ; Humans ; Ligands ; Loss of Function Mutation ; Obesity/genetics ; Protein Binding ; Protein Conformation ; Receptor Activity-Modifying Proteins/chemistry ; Receptor Activity-Modifying Proteins/metabolism ; Receptor, Melanocortin, Type 4/antagonists & inhibitors ; Receptor, Melanocortin, Type 4/genetics ; alpha-MSH/chemistry ; alpha-MSH/pharmacology

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Skocz do pozycji: 4.

Tytuł:: The expanding repertoire of receptor activity modifying protein (RAMP) function.
Autorzy:: Klein KR; a Department of Cell Biology & Physiology and.
Matson BC; a Department of Cell Biology & Physiology and.
Caron KM; a Department of Cell Biology & Physiology and.; b Department of Genetics , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.; Pokaż więcej
Źródło:: Critical reviews in biochemistry and molecular biology [Crit Rev Biochem Mol Biol] 2016; Vol. 51 (1), pp. 65-71. Date of Electronic Publication: 2016 Jan 06.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms:: Receptor Activity-Modifying Proteins/*physiology
Ligands ; Phylogeny ; Protein Binding ; Receptor Activity-Modifying Proteins/metabolism ; Signal Transduction

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Skocz do pozycji: 5.

Tytuł:: Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.
Autorzy:: Asai M; Division of Endocrinology, Department of Medicine, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA.
Ramachandrappa S
Joachim M
Shen Y
Zhang R
Nuthalapati N
Ramanathan V
Strochlic DE
Ferket P
Linhart K
Ho C
Novoselova TV
Garg S
Ridderstråle M
Marcus C
Hirschhorn JN
Keogh JM
O'Rahilly S
Chan LF
Clark AJ
Farooqi IS
Majzoub JA; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2013 Jul 19; Vol. 341 (6143), pp. 275-8.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Body Weight/*genetics
Carrier Proteins/*genetics
Obesity/*genetics
Receptor Activity-Modifying Proteins/*metabolism
Receptor, Melanocortin, Type 4/*metabolism
Adaptor Proteins, Signal Transducing ; Adolescent ; Animals ; Body Mass Index ; Child ; Child, Preschool ; Energy Metabolism/genetics ; Female ; Gene Deletion ; Humans ; Male ; Mice ; Mice, Knockout ; Obesity/metabolism ; Receptor Activity-Modifying Proteins/genetics ; Receptor, Melanocortin, Type 4/genetics ; Young Adult

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Skocz do pozycji: 6.

Tytuł:: Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish.
Autorzy:: Sebag JA; Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Zhang C
Hinkle PM
Bradshaw AM
Cone RD; Pokaż więcej
Źródło:: Science (New York, N.Y.) [Science] 2013 Jul 19; Vol. 341 (6143), pp. 278-81.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptor Activity-Modifying Proteins/*metabolism
Receptor, Melanocortin, Type 4/*metabolism
Zebrafish/*embryology
Zebrafish Proteins/*metabolism
Animals ; Embryo, Nonmammalian/metabolism ; Energy Metabolism ; HEK293 Cells ; Humans ; Receptor Activity-Modifying Proteins/genetics ; Zebrafish/metabolism ; Zebrafish Proteins/genetics ; alpha-MSH/metabolism ; alpha-MSH/pharmacology

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Skocz do pozycji: 7.

Tytuł:: Receptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function.
Autorzy:: Qi T; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Dong M
Watkins HA
Wootten D
Miller LJ
Hay DL; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2013 Feb; Vol. 168 (3), pp. 644-57.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptor Activity-Modifying Proteins/*metabolism
Receptors, Calcitonin/*genetics
Receptors, Calcitonin/*metabolism
Animals ; COS Cells ; Chlorocebus aethiops ; Cyclic AMP/metabolism ; HEK293 Cells ; Humans ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Peptides/pharmacology ; Protein Isoforms ; Receptor Activity-Modifying Proteins/genetics ; Receptors, Calcitonin/agonists ; Receptors, Calcitonin/antagonists & inhibitors ; STAT5 Transcription Factor

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Skocz do pozycji: 8.

Tytuł:: A novel role for pigment genes in the stress response in rainbow trout (Oncorhynchus mykiss).
Autorzy:: Khan UW; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.
Øverli Ø; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.
Hinkle PM; University of Rochester Medical Center, School of Medicine and Dentistry, Department of Pharmacology and Physiology, Rochester, NY 14642, USA.
Pasha FA; KAUST catalysis center (KCC), King Abdullah University of Science and Technology, Thuwal 23955, Saudi Arabia.
Johansen IB; Department of Molecular Biosciences, University of Oslo, NO-0316 Oslo, Norway.
Berget I; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.
Silva PI; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.
Kittilsen S; Norwegian School of Veterinary Medicine, Institute of Basal Sciences and Aquatic Medicine, NO- 0033 Oslo, Norway.
Höglund E; Technical University of Denmark, National Institute of Aquatic Resources, DK-9850 Hirtshals, Denmark.; Norwegian Institute for Water Research (NIVA), NO-0349 Oslo, Norway.
Omholt SW; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.; NTNU - Norwegian University of Science and Technology, NO-7491 Trondheim, Norway.
Våge DI; Centre for Integrative Genetics, Department of Animal and Aquacultural Sciences, Norwegian University of Life Sciences, NO-1430 Ås, Norway.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jul 04; Vol. 6, pp. 28969. Date of Electronic Publication: 2016 Jul 04.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation*
Stress, Physiological*
Oncorhynchus mykiss/*physiology
Receptor Activity-Modifying Proteins/*metabolism
Receptor, Melanocortin, Type 2/*biosynthesis
Receptors, Pituitary Hormone/*metabolism
Animals ; Gene Expression ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Mutation, Missense ; Protein Binding ; RNA, Messenger/biosynthesis ; Receptors, Pituitary Hormone/genetics

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Skocz do pozycji: 9.

Tytuł:: Intermedin suppresses pressure overload cardiac hypertrophy through activation of autophagy.
Autorzy:: Chen H; Molecular Medicine Research Center, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China.
Wang X
Tong M
Wu D
Wu S
Chen J
Wang X
Wang X
Kang Y
Tang H
Tang C
Jiang W; Pokaż więcej
Źródło:: PloS one [PLoS One] 2013 May 29; Vol. 8 (5), pp. e64757. Date of Electronic Publication: 2013 May 29 (Print Publication: 2013).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autophagy*
Hypertrophy, Left Ventricular/*metabolism
Neuropeptides/*metabolism
Animals ; Apoptosis/genetics ; Cell Line ; Cyclic AMP/biosynthesis ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Echocardiography ; Fibrosis ; Heart Ventricles/metabolism ; Heart Ventricles/pathology ; Hypertrophy, Left Ventricular/diagnosis ; Hypertrophy, Left Ventricular/genetics ; Hypertrophy, Left Ventricular/physiopathology ; MAP Kinase Signaling System ; Male ; Mice ; Myocardium/metabolism ; Myocardium/pathology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Neuropeptides/genetics ; Neuropeptides/pharmacology ; Receptor Activity-Modifying Proteins/genetics ; Receptor Activity-Modifying Proteins/metabolism ; Ventricular Dysfunction, Left/diagnosis ; Ventricular Dysfunction, Left/etiology ; Ventricular Remodeling/genetics

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Skocz do pozycji: 10.

Tytuł:: A role for the sensory neuropeptide calcitonin gene-related peptide in endothelial cell proliferation in vivo.
Autorzy:: Mapp PI; Arthritis Research UK Pain Centre, University of Nottingham, City Hospital, Nottingham, UK. />McWilliams DF
Turley MJ
Hargin E
Walsh DA; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2012 Jun; Vol. 166 (4), pp. 1261-71.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Proliferation*/drug effects
Angiogenic Proteins/*metabolism
Calcitonin Gene-Related Peptide/*metabolism
Endothelial Cells/*metabolism
Receptors, Calcitonin Gene-Related Peptide/*metabolism
Signal Transduction/*drug effects
Synovitis/*metabolism
Adult ; Aged ; Aged, 80 and over ; Angiogenic Proteins/antagonists & inhibitors ; Angiogenic Proteins/chemistry ; Animals ; Calcitonin Gene-Related Peptide/analogs & derivatives ; Calcitonin Gene-Related Peptide/antagonists & inhibitors ; Calcitonin Gene-Related Peptide Receptor Antagonists ; Calcitonin Receptor-Like Protein/genetics ; Calcitonin Receptor-Like Protein/metabolism ; Disease Models, Animal ; Endothelial Cells/drug effects ; Endothelial Cells/immunology ; Humans ; Macrophages/drug effects ; Macrophages/immunology ; Macrophages/metabolism ; Male ; Middle Aged ; Molecular Targeted Therapy ; Rats ; Rats, Wistar ; Receptor Activity-Modifying Proteins/genetics ; Receptor Activity-Modifying Proteins/metabolism ; Synovial Fluid/metabolism ; Synovitis/drug therapy ; Synovitis/immunology ; Synovitis/pathology

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Skocz do pozycji: 11.

Tytuł:: Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.
Autorzy:: Magalhaes AC; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada.
Dunn H; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada.
Ferguson SS; J. Allyn Taylor Centre for Cell Biology, Molecular Brain Research Group, Robarts Research Institute, London, ON, CanadaThe Department of Physiology & Pharmacology, the University of Western Ontario, London, ON, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2012 Mar; Vol. 165 (6), pp. 1717-1736.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Receptors, G-Protein-Coupled/*metabolism
Animals ; Arrestins/metabolism ; G-Protein-Coupled Receptor Kinases/metabolism ; GTP-Binding Proteins/metabolism ; Humans ; Protein Transport ; Receptor Activity-Modifying Proteins/metabolism ; Vesicular Transport Proteins/metabolism