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Tytuł:
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants.
Autorzy:
Materna M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Delmonte OM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Bosticardo M; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Momenilandi M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Conrey PE; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Charmeteau-De Muylder B; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.
Bravetti C; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.; Sorbonne University, Paris Cancer Institute CURAMUS, INSERM U1138, Paris, France.
Bellworthy R; Deptartment of Human Genetics, Dahdaleh Institute of Genomic Medicine, McGill University, Montreal, QC, Canada.
Cederholm A; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Staels F; Allergy and Clinical Immunology Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Ganoza CA; Centogene GmbH, Rostock, Germany.
Darko S; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sayed S; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Le Floc'h C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Ogishi M; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Rinchai D; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Guenoun A; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Bolze A; Helix, San Mateo, CA, USA.
Khan T; Department of Human Immunology, Sidra Medicine, Doha, Qatar.; The Jackson Laboratory, Farmington, CT, USA.
Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Krüger R; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Völler M; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.
Palterer B; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Sadeghi-Shabestari M; Immunology Research Center, TB and Lung Disease Research Center, Mardaniazar Children Hospital, Tabriz University of Medical Science, Tabriz, Iran.
Langlois de Septenville A; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.
Schramm CA; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Shah S; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Tello-Cajiao JJ; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Pala F; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Amini K; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Campos JS; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lima NS; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Eriksson D; Department of Immunology, Genetics and Pathology, Uppsala University and University Hospital, Section of Clinical Genetics, Uppsala, Sweden.
Lévy R; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
Seeleuthner Y; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Jyonouchi S; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Ata M; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Al Ali F; Department of Human Immunology, Sidra Medicine, Doha, Qatar.
Stittrich A; Labor Berlin Charité-Vivantes GmbH, Department of Human Genetics, Berlin, Germany.
Deswarte C; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Pereira A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Mégret J; Cytometry Core Facility, SFR Necker, INSERM US24-CNRS UAR3633, Paris, France.
Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Pediatric Immunology, Hematology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France.
Berteloot L; Department of Pediatric Radiology, University Hospital Necker-Enfants Malades, AP-HP, Paris, France.
Dussiot M; Imagine Institute, University of Paris-Cité, Paris, France.; Laboratory of Molecular Mechanisms of Hematological Disorders and Therapeutic Implications, INSERM UMR 1163, Paris, France.
Vladikine N; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Cardenas PP; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain.
Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Alqahtani M; Department of Translational Genomics, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Hasan A; Department of Translational Research, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Thanaraj TA; Department of Genetics and Bioinformatics, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.
Al Qureshah F; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Sabato V; Department of Immunology, Allergology and Rheumatology, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Alyanakian MA; Immunology Laboratory, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France.
Leruez-Ville M; Necker Hospital for Sick Children, AP-HP, Paris, France.
Rozenberg F; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.; Virology, Cochin Hospital, AP-HP, APHP-CUP, Paris, France.
Haddad E; Department of Pediatrics, Department of Microbiology, Immunology and Infectious Diseases, University of Montreal, CHU Sainte-Justine, Montreal, QC, Canada.
Regueiro JR; Department of Immunology, Ophthalmology and ENT, Complutense University School of Medicine and 12 de Octubre Health Research Institute (imas12), Madrid, Spain.
Toribio ML; Immune System Development and Function Unit, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas (CSIC), Universidad Autónoma de Madrid (UAM), Madrid, Spain.
Kelsen JR; Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Salehi M; Cellular, Molecular and Genetics Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.; Department of Genetics and Molecular Biology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.
Nasiri S; Department of Pediatric Neurology, Children's Medical Center of Abuzar, Jundishapur University of Medical Sciences, Ahvaz, Iran.
Torabizadeh M; Golestan Hospital Clinical Research Development Unit, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Rokni-Zadeh H; Department of Medical Biotechnology, School of Medicine, Zanjan University of Medical Sciences (ZUMS), Zanjan, Iran.
Changi-Ashtiani M; School of Mathematics, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
Vatandoost N; Department of Genetics and Molecular Biology, Medical School, Isfahan University of Medical Sciences, Isfahan, Iran.; Pediatric Inherited Diseases Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran.
Moravej H; Neonatal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Akrami SM; Medical Genetics Poursina St., Genetic Department, Medical Faculty, Tehran University of Medical Sciences, Tehran, Iran.; Dr. Shahrooei Laboratory, Tehran, Iran.
Mazloomrezaei M; Dr. Shahrooei Laboratory, Tehran, Iran.
Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Meyts I; Laboratory for Inborn Errors of Immunity, Department of Microbiology, Immunology and Transplantation, Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.; Department of Pediatrics, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Toyofuku E; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.
Nishimura M; Department of Pediatrics, NHO Kumamoto Medical Center, Kumamoto, Japan.
Moriya K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Mizukami T; Department of Pediatrics, NHO Kumamoto Medical Center, Kumamoto, Japan.
Imai K; Department of Pediatrics, National Defense Medical College, Saitama, Japan.
Abel L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
Malissen B; Immunology Center of Marseille-Luminy, Aix Marseille University, Inserm, CNRS, Marseille, France.; Immunophenomics Center (CIPHE), Aix Marseille Université, Inserm, CNRS, Marseille, France.
Al-Mulla F; Department of Genetics and Bioinformatics, Research Division, Dasman Diabetes Institute, Dasman, Kuwait City, Kuwait.
Alkuraya FS; Department of Translational Genomics, Center for Genomic Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.; Department of Anatomy and Cell Biology, College of Medicine, Alfaisal University, Riyadh, Saudi Arabia.
Parvaneh N; Division of Allergy and Clinical Immunology, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran.
von Bernuth H; Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin, Germany.; Labor Berlin GmbH, Department of Immunology, Berlin, Germany.
Beetz C; Centogene GmbH, Rostock, Germany.
Davi F; Department of Biological Hematology, Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP) and Sorbonne Université, Paris, France.; Sorbonne University, Paris Cancer Institute CURAMUS, INSERM U1138, Paris, France.
Douek DC; Human Immunology Section, Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Cheynier R; University of Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Paris, France.
Langlais D; Deptartment of Human Genetics, Dahdaleh Institute of Genomic Medicine, McGill University, Montreal, QC, Canada.
Landegren N; Science for Life Laboratory, Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Center for Molecular Medicine, Department of Medicine (Solna), Karolinska Institute, Stockholm, Sweden.
Marr N; Department of Human Immunology, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.
Morio T; Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.
Shahrooei M; Dr. Shahrooei Laboratory, Tehran, Iran.; Clinical and Diagnostic Immunology, Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium.
Schrijvers R; Allergy and Clinical Immunology Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Henrickson SE; Division of Allergy Immunology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Luche H; Immunophenomics Center (CIPHE), Aix Marseille Université, Inserm, CNRS, Marseille, France.
Notarangelo LD; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Department of Pediatrics, Necker Hospital for Sick Children, AP-HP, Paris, France.; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA.
Béziat V; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Necker Hospital for Sick Children, Paris, France.; Imagine Institute, University of Paris-Cité, Paris, France.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Mar; Vol. 383 (6686), pp. eadh4059. Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article
MeSH Terms:
Autoimmunity*/genetics
Intraepithelial Lymphocytes*/immunology
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Membrane Glycoproteins*/genetics
Humans ; Cell Differentiation ; Homozygote ; Loss of Function Mutation ; Lymphocyte Count ; Alleles ; Infections/immunology ; Lymphoproliferative Disorders/immunology ; Pedigree ; Male ; Female ; Middle Aged ; Aged ; Aged, 80 and over
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Analysis of thymic generation of shared T-cell receptor α repertoire associated with recognition of tumor antigens shows no preference for neoantigens over wild-type antigens.
Autorzy:
Mattila J; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.
Sormunen S; Department of Computer Science, Aalto University, Espoo, Finland.
Heikkilä N; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.; Faculty of Medicine, Center for Vaccinology, Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland.
Mattila IP; Department of Pediatric Cardiac and Transplantation Surgery, Hospital for Children and Adolescents, Helsinki University Central Hospital, Helsinki, Finland.
Saramäki J; Department of Computer Science, Aalto University, Espoo, Finland.
Arstila TP; Research Programs Unit, Translational Immunology, Haartmaninkatu 3 (PL 21) 00014, and Medicum, University of Helsinki, Helsinki, Finland.
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Źródło:
Cancer medicine [Cancer Med] 2023 Jun; Vol. 12 (12), pp. 13486-13496. Date of Electronic Publication: 2023 Apr 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Thymus Gland*/immunology
Antigens, Neoplasm*/genetics
Antigens, Neoplasm*/immunology
Neoplasms*/genetics
Neoplasms*/immunology
Neoplasms*/therapy
Immune Tolerance*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/immunology
Humans ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Selection, engineering, and in vivo testing of a human leukocyte antigen-independent T-cell receptor recognizing human mesothelin.
Autorzy:
Hiscox MJ; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Wasmuth A; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Williams CL; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Foot JN; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Wiedermann GE; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Fadda V; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Boiani S; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Cornforth TV; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Wikiert KA; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Bruton S; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Cartwright N; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Anderson VE; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Barnes CS; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Vieira JV; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Birch-Machin I; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Gerry AB; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Miller K; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
Pumphrey NJ; Research, Adaptimmune, Abingdon, Oxfordshire, United Kingdom.
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Źródło:
PloS one [PLoS One] 2024 Apr 04; Vol. 19 (4), pp. e0301175. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Mesothelin*
Neoplasms*/metabolism
Humans ; CD8-Positive T-Lymphocytes ; Receptors, Antigen, T-Cell ; Antigens, Neoplasm/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; HLA Antigens/metabolism ; Histocompatibility Antigens Class II/metabolism ; Peptides/metabolism ; Histocompatibility Antigens/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
GPR43 stimulation on TCRαβ intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity.
Autorzy:
Prado C; Laboratorio de Neuroinmunología, Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile. .; Facultad de Medicina y Ciencia, Universidad San Sebastián, 7510156, Providencia, Santiago, Chile. .
Espinoza A; Laboratorio de Neuroinmunología, Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.
Martínez-Hernández JE; Laboratorio de Redes Biológicas, Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.; Agriaquaculture Nutritional Genomic Center, Temuco, Chile.
Petrosino J; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
Riquelme E; Respiratory Diseases Department, Faculty of Medicine, Pontifical Catholic University of Chile, Santiago, Chile.
Martin AJM; Laboratorio de Redes Biológicas, Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile.; Escuela de Ingeniería, Facultad de Ingeniería Arquitectura y Diseño, Universidad San Sebastián, Providencia, Chile.
Pacheco R; Laboratorio de Neuroinmunología, Centro Científico y Tecnológico de Excelencia Ciencia & Vida, Fundación Ciencia & Vida, Avenida Del Valle Norte #725, 8580702, Huechuraba, Santiago, Chile. .; Facultad de Medicina y Ciencia, Universidad San Sebastián, 7510156, Providencia, Santiago, Chile. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2023 Jun 01; Vol. 20 (1), pp. 135. Date of Electronic Publication: 2023 Jun 01.
Typ publikacji:
Journal Article
MeSH Terms:
Receptors, Antigen, T-Cell, alpha-beta*
Encephalomyelitis, Autoimmune, Experimental*
Mice ; Animals ; Autoimmunity ; Dysbiosis ; Central Nervous System ; Myelin-Oligodendrocyte Glycoprotein/toxicity ; Peptides ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients.
Autorzy:
Jirouš Drulak M; Department of Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia. .
Grgić Z; Department of Laboratory Medicine and Pharmacy, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Plužarić V; Department of Laboratory Medicine and Pharmacy, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Dermatology and Venerology, University Hospital Osijek, Osijek, Croatia.
Šola M; Department of Dermatology and Venerology, University Hospital Osijek, Osijek, Croatia.
Opačak-Bernardi T; Department of Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Viljetić B; Department of Medical Chemistry, Biochemistry and Clinical Chemistry, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Glavaš K; Department of Transfusion Medicine, University Hospital Osijek, Osijek, Croatia.
Tolušić-Levak M; Department of Dermatology and Venerology, University Hospital Osijek, Osijek, Croatia.; Department of Histology and Embryology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Periša V; Department of Internal Medicine and History of Medicine, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.; Department of Hematology, Clinic of Internal Medicine, University Hospital Osijek, Osijek, Croatia.
Mihalj M; Department of Dermatology and Venerology, University Hospital Osijek, Osijek, Croatia.; Department of Physiology and Immunology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
Štefanić M; Department of Nuclear Medicine and Oncology, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia. .
Tokić S; Department of Laboratory Medicine and Pharmacy, Faculty of Medicine, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 28; Vol. 13 (1), pp. 20990. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Mucosal-Associated Invariant T Cells*
Psoriasis*/metabolism
Adult ; Humans ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; T-Lymphocyte Subsets ; Mucous Membrane/metabolism ; Histocompatibility Antigens Class I/metabolism ; Minor Histocompatibility Antigens/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Colonic mucosal associated invariant T cells in Crohn's disease have a diverse and non-public T cell receptor beta chain repertoire.
Autorzy:
Konecny AJ; Benaroya Research Institute, Translational Research Program, Seattle, WA, United States of America.; Department of Immunology, University of Washington, Seattle, WA, United States of America.
Shows DM; Benaroya Research Institute, Translational Research Program, Seattle, WA, United States of America.
Lord JD; Benaroya Research Institute, Translational Research Program, Seattle, WA, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Nov 03; Vol. 18 (11), pp. e0285918. Date of Electronic Publication: 2023 Nov 03 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mucosal-Associated Invariant T Cells*
Crohn Disease*/genetics
Crohn Disease*/metabolism
Humans ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism ; Histocompatibility Antigens Class I/genetics ; Receptors, Antigen, T-Cell/metabolism ; Colon/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Physiological and Functional Effects of Dominant Active TCRα Expression in Transgenic Mice.
Autorzy:
Kalinina AA; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Ziganshin RK; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Miklukho-Maklaya st. 16/10, 117997 Moscow, Russia.
Silaeva YY; Institute of Gene Biology, Russian Academy of Sciences, Vavilova st. 34/5, 119334 Moscow, Russia.
Sharova NI; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Nikonova MF; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Persiyantseva NA; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Gorkova TG; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Antoshina EE; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Trukhanova LS; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Donetskova AD; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Komogorova VV; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Litvina MM; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Mitin AN; National Research Center, Institute of Immunology Federal Medical-Biological Agency of Russia, Kashirskoe sh., 24, 115522 Moscow, Russia.
Zamkova MA; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.; Institute of Gene Biology, Russian Academy of Sciences, Vavilova st. 34/5, 119334 Moscow, Russia.
Bruter AV; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilov St., 119334 Moscow, Russia.
Khromykh LM; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
Kazansky DB; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Kashirskoe sh., 24, 115478 Moscow, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 30; Vol. 24 (7). Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes*
Receptors, Antigen, T-Cell, alpha-beta*
Mice ; Animals ; Mice, Transgenic ; Receptors, Antigen, T-Cell/genetics ; Receptors, Antigen, T-Cell/metabolism ; Lymphocytes/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Contribution of the TCRβ Repertoire to Marek's Disease Genetic Resistance in the Chicken.
Autorzy:
Hearn CJ; Avian Disease and Oncology Laboratory, US National Poultry Research Center, Agricultural Research Service, USDA, East Lansing, MI 48823, USA.
Cheng HH; Avian Disease and Oncology Laboratory, US National Poultry Research Center, Agricultural Research Service, USDA, East Lansing, MI 48823, USA.
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Źródło:
Viruses [Viruses] 2023 Feb 22; Vol. 15 (3). Date of Electronic Publication: 2023 Feb 22.
Typ publikacji:
Journal Article
MeSH Terms:
Herpesvirus 2, Gallid*
Marek Disease*/genetics
Marek Disease*/immunology
Disease Resistance*/genetics
Receptors, Antigen, T-Cell, alpha-beta*
Animals ; CD8-Positive T-Lymphocytes ; Chickens
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication.
Autorzy:
Yin Y; Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, 250014, China.
Sheng Y; Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, 250014, China.
Gao S; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China.
Zhang J; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China.
Wang W; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China.
Liu Y; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China.
Xu T; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China.
Zhang Y; Shandong University of Traditional Chinese Medicine, 203, Administrative Building, 4655 University Road, Changqing District, Jinan, Shandong, 250035, China. .
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Źródło:
BMC immunology [BMC Immunol] 2024 Jan 31; Vol. 25 (1), pp. 10. Date of Electronic Publication: 2024 Jan 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes*
Diabetes Mellitus, Type 2*
Humans ; Receptors, Antigen, T-Cell/genetics ; Gene Expression ; High-Throughput Nucleotide Sequencing ; Receptors, Antigen, T-Cell, alpha-beta/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High-throughput sequencing reveals the change of TCR α chain CDR3 with Takayasu arteritis.
Autorzy:
Zha B; Department of Education, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Pan L; Department of Rheumatology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Gao N; Department of Rheumatology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2023 Dec; Vol. 11 (12), pp. e1122.
Typ publikacji:
Journal Article
MeSH Terms:
Complementarity Determining Regions*/genetics
Takayasu Arteritis*/diagnosis
Takayasu Arteritis*/genetics
Humans ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; High-Throughput Nucleotide Sequencing
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single cell and spatial transcriptomics analysis of kidney double negative T lymphocytes in normal and ischemic mouse kidneys.
Autorzy:
Gharaie S; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Lee K; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Noller K; Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Lo EK; Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Miller B; Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Jung HJ; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Newman-Rivera AM; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Kurzhagen JT; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Singla N; Department of Urology, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Welling PA; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.; Department of Physiology, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Fan J; Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Cahan P; Department of Biomedical Engineering, Johns Hopkins University, School of Medicine, Baltimore, MD, 21205, USA.
Noel S; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA.
Rabb H; Department of Medicine, Johns Hopkins University, School of Medicine, Ross 965, 720 Rutland Ave, Baltimore, MD, 21205, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 28; Vol. 13 (1), pp. 20888. Date of Electronic Publication: 2023 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
CD8-Positive T-Lymphocytes*/metabolism
Acute Kidney Injury*/pathology
Humans ; Animals ; Mice ; Transcriptome ; CD8 Antigens/metabolism ; CD4 Antigens/metabolism ; Kidney/metabolism ; Receptors, Antigen, T-Cell, alpha-beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Automatic generation of alloreactivity-reduced donor lymphocytes and hematopoietic stem cells from the same mobilized apheresis product.
Autorzy:
Wiercinska E; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Quade-Lyssy P; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Hümmer C; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Beifuß J; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Akarkach K; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Poppe C; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany.; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany.
Olevska V; Miltenyi Biotec B.V. & CO. KG, Bergisch Gladbach, Germany.
Dzionek J; Miltenyi Biotec B.V. & CO. KG, Bergisch Gladbach, Germany.
Lahnor H; Miltenyi Biomedicine GmbH, Bergisch Gladbach, Germany.
Bosio A; Miltenyi Biotec B.V. & CO. KG, Bergisch Gladbach, Germany.
Papanikolaou E; Miltenyi Biotec B.V. & CO. KG, Bergisch Gladbach, Germany.; Laboratory of Biology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Bonig H; Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt, Germany. .; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt, Germany. .; Department of Medicine, Division of Hematology, University of Washington, Seattle, WA, USA. .; DRK-BSD BaWüHe, Sandhofstraße 1, 60528, Frankfurt, Germany. .
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Źródło:
Journal of translational medicine [J Transl Med] 2023 Nov 25; Vol. 21 (1), pp. 849. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Component Removal*/methods
Hematopoietic Stem Cell Transplantation*/methods
Anemia*
Humans ; Lymphocyte Depletion/methods ; T-Lymphocytes ; Hematopoietic Stem Cells ; Tissue Donors ; Receptors, Antigen, T-Cell, alpha-beta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immune repertoire analysis of normal Chinese donors at different ages.
Autorzy:
Song C; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Pan W; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.; Nanjing ARP Biotechnology Co., Ltd., Nanjing, China.
Brown B; iRepertoire Inc., Huntsville, Alabama, USA.
Tang C; Nanjing ARP Biotechnology Co., Ltd., Nanjing, China.
Huang Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Chen H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Peng N; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Wang Z; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.; Guangdong Provincial Hospital of Chinese Medicine & Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
Weber D; iRepertoire Inc., Huntsville, Alabama, USA.
Byrne-Steele M; iRepertoire Inc., Huntsville, Alabama, USA.
Wu H; Department of Dermatology, Second Xiangya Hospital, Hunan Key Laboratory of Medical Epigenomics, Central South University, Changsha, China.
Liu H; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.; Nanjing ARP Biotechnology Co., Ltd., Nanjing, China.
Deng Y; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
He N; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
Li S; Hunan Key Laboratory of Biomedical Nanomaterials and Devices, Hunan University of Technology, Zhuzhou, China.
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Źródło:
Cell proliferation [Cell Prolif] 2022 Nov; Vol. 55 (11), pp. e13311. Date of Electronic Publication: 2022 Aug 04.
Typ publikacji:
Journal Article
MeSH Terms:
Complementarity Determining Regions*/genetics
Complementarity Determining Regions*/metabolism
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/metabolism
Humans ; T-Lymphocytes/metabolism ; High-Throughput Nucleotide Sequencing/methods ; China
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Human thymic putative CD8αα precursors exhibit a biased TCR repertoire in single cell AIRR-seq.
Autorzy:
Heimli M; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Tennebø Flåm S; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Sagsveen Hjorthaug H; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Bjørnstad PM; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Chernigovskaya M; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Le QK; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Tekpli X; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway.
Greiff V; Department of Immunology, University of Oslo and Oslo University Hospital, 0372, Oslo, Norway.
Lie BA; Department of Medical Genetics, University of Oslo and Oslo University Hospital, 0424, Oslo, Norway. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 18; Vol. 13 (1), pp. 17714. Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Antigen, T-Cell*/metabolism
Thymocytes*/metabolism
Humans ; Child ; Thymus Gland/metabolism ; T-Lymphocytes, Regulatory ; Complementarity Determining Regions/genetics ; Complementarity Determining Regions/metabolism ; Cell Differentiation ; Receptors, Antigen, T-Cell, alpha-beta/genetics ; Receptors, Antigen, T-Cell, alpha-beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The dephosphorylation of FADD at S191 induces an excessive expansion of TCRαβ IELs in the intestinal mucosa.
Autorzy:
Zhang X; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.; School of Pharmaceutical Sciences, Shandong First Medical University, Taian, China.
Zhu B; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Li L; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Xu J; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Han Y; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Zhang J; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.
Hua Z; The State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, Nanjing, China.; School of Biopharmacy, China Pharmaceutical University, Nanjing, China.; Changzhou High-Tech Research Institute of Nanjing University and Jiangsu Target Pharma Laboratories Inc., Changzhou, China.
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Źródło:
Immunology [Immunology] 2022 Oct; Vol. 167 (2), pp. 233-246. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Intraepithelial Lymphocytes*/metabolism
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Receptors, Antigen, T-Cell, alpha-beta*/metabolism
Animals ; CD8-Positive T-Lymphocytes/metabolism ; Fas-Associated Death Domain Protein/genetics ; Fas-Associated Death Domain Protein/metabolism ; Intestinal Mucosa/metabolism ; Mice ; Mice, Inbred C57BL ; NF-kappa B/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clonal dynamics underlying the skewed CD4/CD8 ratio of mouse thymocytes revealed by TCR-independent barcoding.
Autorzy:
Iwanami N; Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, D-79108, Freiburg, Germany.; Center for Bioscience Research and Education, Utsunomiya University, Utsunomiya, Tochigi, 321-8505, Japan.
Petersen M; Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, D-79108, Freiburg, Germany.; High Performance Computing & Analytics Lab, University of Bonn, Friedrich-Hirzebruch-Allee 8, D-53115, Bonn, Germany.
Diekhoff D; Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, D-79108, Freiburg, Germany.
Boehm T; Department of Developmental Immunology, Max Planck Institute of Immunobiology and Epigenetics, Stuebeweg 51, D-79108, Freiburg, Germany. .; Faculty of Medicine, Albert Ludwigs University, Breisacher Strasse 153, D-79110, Freiburg, Germany. .
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Źródło:
Communications biology [Commun Biol] 2022 Sep 05; Vol. 5 (1), pp. 911. Date of Electronic Publication: 2022 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Antigen, T-Cell, alpha-beta*/genetics
Thymocytes*
Animals ; CD4-Positive T-Lymphocytes ; CD8-Positive T-Lymphocytes ; Cells, Cultured ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
TCR repertoire and transcriptional signatures of circulating tumour-associated T cells facilitate effective non-invasive cancer detection.
Autorzy:
Ji F; Tsinghua-Peking Center for Life Sciences, MOE Key Laboratory of Tsinghua University, Beijing, China.; School of Medicine, Tsinghua University, Beijing, China.
Chen L; School of Medicine, Tsinghua University, Beijing, China.; General Surgery Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Chen Z; School of Life Science, Tsinghua University, Beijing, China.
Luo B; General Surgery Department, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Wang Y; Department of Anesthesiology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Lan X; Tsinghua-Peking Center for Life Sciences, MOE Key Laboratory of Tsinghua University, Beijing, China.; School of Medicine, Tsinghua University, Beijing, China.
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Źródło:
Clinical and translational medicine [Clin Transl Med] 2022 Sep; Vol. 12 (9), pp. e853.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*
Receptors, Antigen, T-Cell, alpha-beta*
CD8-Positive T-Lymphocytes ; Humans
Raport
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Computational discovery of binding mode of anti-TRBC1 antibody and predicted key amino acids of TRBC1.
Autorzy:
Saetang J; Division of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.; International Center of Excellence in Seafood Science and Innovation, Faculty of Agro-Industry, Prince of Songkla University, Songkhla, 90110, Thailand.; EZ-Mol-Design Laboratory, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Sangkhathat S; Division of Surgery, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Jangphattananont N; Stem Cell Laboratory, Hematology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Khopanlert W; Stem Cell Laboratory, Hematology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.; Division of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand.
Julamanee J; Stem Cell Laboratory, Hematology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. .
Tipmanee V; EZ-Mol-Design Laboratory, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. .; Division of Biomedical Sciences and Biomedical Engineering, Faculty of Medicine, Prince of Songkla University, Songkhla, 90110, Thailand. .
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Źródło:
Scientific reports [Sci Rep] 2022 Feb 02; Vol. 12 (1), pp. 1760. Date of Electronic Publication: 2022 Feb 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lymphoma, T-Cell, Peripheral*/immunology
Lymphoma, T-Cell, Peripheral*/metabolism
Protein Binding*
Receptors, Antigen, T-Cell, alpha-beta*/chemistry
Receptors, Antigen, T-Cell, alpha-beta*/immunology
Antibodies, Monoclonal/*chemistry
Amino Acids/chemistry ; Computational Biology/methods ; Epitopes/chemistry ; Humans ; Molecular Docking Simulation ; T-Lymphocytes/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Double-negative T cells: Setting the stage for disease control or progression.
Autorzy:
Velikkakam T; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Pós-graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Gollob KJ; Hospital Israelita Albert Einsten, São Paulo, Brazil.; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais - INCT-DT, Belo Horizonte, Brazil.
Dutra WO; Departamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Pós-graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.; Instituto Nacional de Ciência e Tecnologia em Doenças Tropicais - INCT-DT, Belo Horizonte, Brazil.
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Źródło:
Immunology [Immunology] 2022 Apr; Vol. 165 (4), pp. 371-385. Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Receptors, Antigen, T-Cell, alpha-beta*
T-Lymphocyte Subsets*
Animals ; CD4 Antigens ; CD8 Antigens ; Lymphocyte Count ; Receptors, Antigen, T-Cell, gamma-delta
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An open protocol for modeling T Cell Clonotype repertoires using TCRβ CDR3 sequences.
Autorzy:
Gurun B; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. .; School of Medicine, Oregon Health and Science University, Portland, OR, USA. .
Horton W; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Murugan D; Department of Cell, Developmental & Cancer Biology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Zhu B; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.
Leyshock P; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Kumar S; Department of Cell, Developmental & Cancer Biology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.
Byrne KT; Department of Cell, Developmental & Cancer Biology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Vonderheide RH; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Margolin AA; NextVivo, Palo Alto, CA, USA.
Mori M; Department of Biostatistics, St. Jude's Children's Research Hospital, Memphis, TN, USA.
Spellman PT; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. .
Coussens LM; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. .; Department of Cell, Developmental & Cancer Biology and Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. .
Speed TP; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia. .; School of Mathematics and Statistics, University of Melbourne, Parkville, VIC, 3010, Australia. .
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Źródło:
BMC genomics [BMC Genomics] 2023 Jun 26; Vol. 24 (1), pp. 349. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji:
Journal Article
MeSH Terms:
High-Throughput Nucleotide Sequencing*/methods
T-Lymphocytes*
Base Sequence ; Chromosome Mapping ; Receptors, Antigen, T-Cell, alpha-beta/genetics
Czasopismo naukowe
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