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Wyszukujesz frazę ""Receptors, CXCR3"" wg kryterium: Temat


Tytuł:
Lipoxins A 4 and B 4 inhibit glial cell activation via CXCR3 signaling in acute retinal neuroinflammation.
Autorzy:
Livne-Bar I; Department of Vision Sciences, Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Krembil Discovery Tower, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada.; Department of Ophthalmology and Vision Science, University of Toronto School of Medicine, Toronto, Canada.
Maurya S; Herbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
Gronert K; Herbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.; Vision Science Program, University of California Berkeley, Berkeley, CA, USA.; Infectious Disease and Immunity Program, University of California Berkeley, Berkeley, CA, USA.
Sivak JM; Department of Vision Sciences, Donald K Johnson Eye Institute, Krembil Research Institute, University Health Network, Krembil Discovery Tower, 60 Leonard Avenue, Toronto, ON, M5T 0S8, Canada. .; Department of Ophthalmology and Vision Science, University of Toronto School of Medicine, Toronto, Canada. .; Department of Laboratory Medicine and Pathobiology, University of Toronto School of Medicine, Toronto, Canada. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Jan 11; Vol. 21 (1), pp. 18. Date of Electronic Publication: 2024 Jan 11.
Typ publikacji:
Journal Article
MeSH Terms:
Lipoxins*/pharmacology
Lipoxins*/metabolism
Neuroglia*/metabolism
Neuroinflammatory Diseases*
Receptors, CXCR3*
Inflammation/chemically induced ; Lipopolysaccharides/toxicity ; Animals
Czasopismo naukowe
Tytuł:
IL-2/GM-CSF enhances CXCR3 expression in CAR-T cells via the PI3K/AKT and ERK1/2 pathways.
Autorzy:
Liu L; College of Medical Technology, Anhui Medical College, Hefei, China.
Cheng Y; Department of Cell Center, The 901th Hospital of PLA Joint Logistic Support Force, Hefei, China.
Zhang F; College of Medical Technology, Anhui Medical College, Hefei, China.
Chen J; College of Medical Technology, Anhui Medical College, Hefei, China.
Tian P; College of Medical Technology, Anhui Medical College, Hefei, China.
Shi W; College of Medical Technology, Anhui Medical College, Hefei, China.
Zhou F; College of Medical Technology, Anhui Medical College, Hefei, China.
Yang M; Department of Hematology, First Affiliated Hospital of Anhui Medical University, Hefei, China.
Zhou M; Department of Critical Care, First Affiliated Hospital of University of Science and Technology, Hefei, China.
Liu B; Department of Cell Center, The 901th Hospital of PLA Joint Logistic Support Force, Hefei, China. .
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Źródło:
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2023 Aug; Vol. 149 (9), pp. 5547-5557. Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/therapy
Carcinoma, Hepatocellular*/metabolism
Liver Neoplasms*/therapy
Liver Neoplasms*/metabolism
Receptors, CXCR3*/metabolism
Receptors, Chimeric Antigen*/metabolism
Animals ; Mice ; CD28 Antigens/metabolism ; Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology ; Granulocyte-Macrophage Colony-Stimulating Factor/metabolism ; Granulocytes ; Interleukin-2/pharmacology ; Leukocytes, Mononuclear ; MAP Kinase Signaling System ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; T-Lymphocytes/metabolism ; Tumor Microenvironment ; Humans
Czasopismo naukowe
Tytuł:
The CXCL10-CXCR3 axis plays an important role in Kawasaki disease.
Autorzy:
Hosaka S; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.
Imagawa K; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba City, Japan.
Yano Y; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.; Department of Pediatric Cardiology, Ibaraki Children's Hospital, Mito City, Japan.
Lin L; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba City, Japan.; Department of Pediatric Cardiology, Ibaraki Children's Hospital, Mito City, Japan.
Shiono J; Department of Pediatric Cardiology, Ibaraki Children's Hospital, Mito City, Japan.
Takahashi-Igari M; Department of Pediatrics, Tsukuba Medical Center Hospital, Tsukuba City, Japan.
Hara H; Department of Pediatrics, Tsukuba Medical Center Hospital, Tsukuba City, Japan.
Hayashi D; Department of Pediatrics, Tsukuba Medical Center Hospital, Tsukuba City, Japan.
Imai H; Department of Pediatrics, Tsukuba Medical Center Hospital, Tsukuba City, Japan.
Morita A; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.
Fukushima H; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba City, Japan.
Takada H; Department of Pediatrics, University of Tsukuba Hospital, Tsukuba City, Japan.; Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba City, Japan.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2024 Mar 12; Vol. 216 (1), pp. 104-111.
Typ publikacji:
Journal Article
MeSH Terms:
Mucocutaneous Lymph Node Syndrome*
Humans ; Chemokine CXCL10 ; Chemokine CXCL9 ; Cytokines ; Th1 Cells ; Monocytes ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Commentary on "Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections".
Autorzy:
Drews SJ; Canadian Blood Services, Microbiology Department, Donor Policy and Studies, Edmonton, Alberta, Canada; Division of Diagnostic and Applied Microbiology, Department of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Alberta, Canada. Electronic address: .
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Źródło:
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Mar; Vol. 22 (3), pp. 609-612.
Typ publikacji:
Journal Article
MeSH Terms:
Encephalitis, Japanese*
Dengue*
Humans ; Platelet Factor 4 ; Immunologic Factors ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Inhibition of cellular activation induced by platelet factor 4 via the CXCR3 pathway ameliorates Japanese encephalitis and dengue viral infections.
Autorzy:
Singh A; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Ghosh R; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Asuru TR; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Prajapat SK; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Joshi G; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Gaur KK; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Shrimali NM; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Ojha A; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India; Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University, Stanford, California, USA.
Vikram NK; Division of Infectious Disease, All India Institute of Medical Sciences, New Delhi, India.
Poncz M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Kalia M; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India.
Guchhait P; Regional Centre for Biotechnology, National Capital Region Biotech Science Cluster, Faridabad, Haryana, India. Electronic address: .
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Źródło:
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2024 Mar; Vol. 22 (3), pp. 818-833. Date of Electronic Publication: 2023 Nov 27.
Typ publikacji:
Journal Article
MeSH Terms:
Dengue*/drug therapy
Dengue*/metabolism
Encephalitis Virus, Japanese*/physiology
Encephalitis, Japanese*/drug therapy
Pyrimidinones*
Animals ; Humans ; Mice ; Acetamides ; Immunologic Factors ; Platelet Factor 4 ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Combination of STING agonist and CXCR3 antagonist disrupts immune tolerance to overcome anti-PD-L1 resistance in lung adenocarcinoma under oxidative stress.
Autorzy:
Zhu L; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China; Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, College of Polymer Science and Engineering, Sichuan University, Chengdu, China. Electronic address: .
Gao H; Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, College of Polymer Science and Engineering, Sichuan University, Chengdu, China. Electronic address: .
Huang S; Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, College of Polymer Science and Engineering, Sichuan University, Chengdu, China. Electronic address: .
Cao T; Laboratory of Infectious Diseases and Vaccine, West China Hospital, Sichuan University, Chengdu, China. Electronic address: .
Zhai X; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: .
Hu J; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: .
Wang T; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: .
Dong J; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: djs_.
Liu Z; Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China. Electronic address: .
Chen J; Department of General Surgery, Sir Run Shaw Hospital, Zhejiang University, Hangzhou, China. Electronic address: .
Liu J; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: jerry_.
Zhang Z; Key Laboratory of Drug Targeting and Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, College of Polymer Science and Engineering, Sichuan University, Chengdu, China. Electronic address: .
Zhou Q; Lung Cancer Center/Lung Cancer Institute, West China Hospital, Sichuan University, Chengdu, China. Electronic address: prof_qh_.
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Źródło:
Gene [Gene] 2023 Jan 30; Vol. 851, pp. 146962. Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/drug therapy
Lung Neoplasms*/diet therapy
Oxidative Stress*
Receptors, CXCR3*/antagonists & inhibitors
Membrane Proteins*/agonists
Animals ; Mice ; B7-H1 Antigen ; Cell Line, Tumor ; Hydrogen Peroxide ; Immune Tolerance ; Tumor Microenvironment ; Drug Resistance, Neoplasm
Czasopismo naukowe
Tytuł:
Clinical Significance of the Pre-Transplant CXCR3 and CCR6 Expression on T Cells In Kidney Graft Recipients.
Autorzy:
Alfaro R; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Llorente S; Nephrology Services; University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Gonzalez-Martínez G; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Jimenez-Coll V; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Martínez-Banaclocha H; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Galián JA; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Botella C; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Moya-Quiles MR; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
de la Peña-Moral J; Pathology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Minguela A; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain.
Legaz I; Department of Legal and Forensic Medicine, Biomedical Research Institute (IMIB), Regional Campus of International Excellence 'Campus Mare Nostrum', Faculty of Medicine, University of Murcia, Murcia, Spain. Electronic address: .
Muro M; Immunology Services, University Clinical Hospital Virgen de la Arrixaca-Biomedical Research Institute of Murcia (IMIB), Murcia, Spain. Electronic address: .
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Źródło:
Transplantation proceedings [Transplant Proc] 2023 Jan-Feb; Vol. 55 (1), pp. 66-71. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Journal Article
MeSH Terms:
Kidney Transplantation*/adverse effects
Receptors, CCR6*/metabolism
Receptors, CXCR3*
Th1 Cells*
Transplant Recipients*
Humans ; Clinical Relevance ; Kidney/metabolism ; Th17 Cells ; Transplantation, Homologous
Czasopismo naukowe
Tytuł:
Location bias contributes to functionally selective responses of biased CXCR3 agonists.
Autorzy:
Eiger DS; Department of Biochemistry, Duke University, Durham, NC, 27710, USA.
Boldizsar N; Trinity College, Duke University, Durham, NC, 27710, USA.
Honeycutt CC; Trinity College, Duke University, Durham, NC, 27710, USA.
Gardner J; Trinity College, Duke University, Durham, NC, 27710, USA.
Kirchner S; Department of Dermatology, Duke University, Durham, NC, 27707, USA.; Department of Molecular Genetics and Microbiology, Duke University, Durham, NC, 27707, USA.
Hicks C; Trinity College, Duke University, Durham, NC, 27710, USA.
Choi I; Department of Medicine, Duke University, Durham, NC, 27710, USA.
Pham U; Department of Biochemistry, Duke University, Durham, NC, 27710, USA.
Zheng K; Harvard Medical School, Boston, MA, 02115, USA.
Warman A; Trinity College, Duke University, Durham, NC, 27710, USA.
Smith JS; Harvard Medical School, Boston, MA, 02115, USA.; Department of Dermatology, Brigham and Women's Hospital, Boston, MA, 02115, USA.; Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.; Dermatology Program, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Dermatology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Zhang JY; Department of Dermatology, Duke University, Durham, NC, 27707, USA.; Department of Pathology, Duke University, Durham, NC, 27710, USA.
Rajagopal S; Department of Biochemistry, Duke University, Durham, NC, 27710, USA. .; Department of Medicine, Duke University, Durham, NC, 27710, USA. .
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Źródło:
Nature communications [Nat Commun] 2022 Oct 04; Vol. 13 (1), pp. 5846. Date of Electronic Publication: 2022 Oct 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
GTP-Binding Proteins*/metabolism
Receptors, CXCR3*/genetics
Receptors, CXCR3*/metabolism
Animals ; Chemokines/metabolism ; Ligands ; Mice ; Receptors, G-Protein-Coupled/metabolism ; beta-Arrestins/metabolism
Czasopismo naukowe
Tytuł:
The duality of CXCR3 in glioblastoma: unveiling autocrine and paracrine mechanisms for novel therapeutic approaches.
Autorzy:
Chan TYH; Division of Neurosurgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Wong JSY; Division of Vascular Surgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Kiang KM; Division of Neurosurgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Sun CWY; Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, Dublin, Republic of Ireland.
Leung GK; Division of Neurosurgery, Department of Surgery, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Dec 16; Vol. 14 (12), pp. 835. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Glioblastoma*/genetics
Glioblastoma*/therapy
Brain Neoplasms*/genetics
Brain Neoplasms*/therapy
Brain Neoplasms*/pathology
Humans ; Chemokine CXCL10 ; Receptors, CXCR3/genetics ; Receptors, CXCR3/metabolism ; Chemokine CXCL9 ; T-Lymphocytes/metabolism ; Ligands
Czasopismo naukowe
Tytuł:
CD8 T cells reduce neuroretina inflammation in mouse by regulating autoreactive Th1 and Th17 cells through IFN-γ.
Autorzy:
Wu S; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhang X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Hu C; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhong Y; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Chen J; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Chong WP; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.; School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, China.
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Źródło:
European journal of immunology [Eur J Immunol] 2023 Dec; Vol. 53 (12), pp. e2350574. Date of Electronic Publication: 2023 Sep 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
CD8-Positive T-Lymphocytes*/drug effects
CD8-Positive T-Lymphocytes*/immunology
Retinitis*/immunology
Interferon-gamma*/immunology
Male ; Female ; Animals ; Mice ; Mice, Inbred C57BL ; Lymphocyte Activation ; Th1 Cells/immunology ; Th17 Cells/immunology ; Cell Polarity/immunology ; Interleukin-10/immunology ; Interferon-beta/pharmacology ; Receptors, CXCR3/genetics ; Receptors, CXCR3/immunology ; Protein Transport/genetics ; Spleen/immunology
Czasopismo naukowe
Tytuł:
Demethylase FTO promotes neuropathic pain development via regulating the m6A methylation levels of CXCR3.
Autorzy:
Wu SF; Department Anesthesiol, The Second Hospital of Dalian Medical University, Dalian, Liaoning116023, China.
Wang Y; Department Anesthesiol, The Second Hospital of Dalian Medical University, Dalian, Liaoning116023, China.
Zhao QC; Department Anesthesiol, The Second Hospital of Dalian Medical University, Dalian, Liaoning116023, China.
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Źródło:
Acta biochimica Polonica [Acta Biochim Pol] 2022 Dec 02; Vol. 69 (4), pp. 819-824.
Typ publikacji:
Journal Article
MeSH Terms:
Alpha-Ketoglutarate-Dependent Dioxygenase FTO*/genetics
Alpha-Ketoglutarate-Dependent Dioxygenase FTO*/metabolism
Neuralgia*/genetics
Receptors, CXCR3*/metabolism
Animals ; Mice ; Methylation ; RNA Stability ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Role of CXCR3 in fibrotic tissue responses.
Autorzy:
Wells A; Departments of Pathology, Bioengineering, and Computational & Systems Biology, and McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA; R&D Service, Pittsburgh VA Health System, Pittsburgh, PA 15213, USA. Electronic address: .
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Źródło:
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2022 Nov; Vol. 152, pp. 106311. Date of Electronic Publication: 2022 Oct 01.
Typ publikacji:
Journal Article
MeSH Terms:
Fibrosis*/genetics
Receptors, CXCR3*/genetics
Wound Healing*/genetics
Wound Healing*/physiology
Humans ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł:
Hyperactivation of β-catenin signal in hepatocellular carcinoma recruits myeloid-derived suppressor cells through PF4-CXCR3 axis.
Autorzy:
Wang K; School of Life Sciences, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, 200438, China.
Wu J; Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, 200438, China.
Yang Z; Eastern Hepatobiliary Surgery Hospital, Shanghai, 200438, China.
Zheng B; The International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China; National Center for Liver Cancer, Shanghai, 200441, China.
Shen S; The International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China; National Center for Liver Cancer, Shanghai, 200441, China.
Wang RR; Berry Oncology Corporation, Digital Fujian Park, Fuzhou, China.
Zhang Y; Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, 200438, China.
Wang HY; The International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China; National Center for Liver Cancer, Shanghai, 200441, China; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, 200438, China; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, 200438, China. Electronic address: .
Chen L; The International Cooperation Laboratory on Signal Transduction, National Center for Liver Cancer, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, 200438, China; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, 200438, China; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, 200438, China; Department of Cancer Institute, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. Electronic address: .
Qiu X; Department of Cancer Institute, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China. Electronic address: xinyao_.
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Źródło:
Cancer letters [Cancer Lett] 2024 Apr 01; Vol. 586, pp. 216690. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Myeloid-Derived Suppressor Cells*/metabolism
Liver Neoplasms*/pathology
Humans ; beta Catenin/metabolism ; CD8-Positive T-Lymphocytes/metabolism ; Wnt Signaling Pathway/genetics ; Cytokines/metabolism ; Cell Line, Tumor ; Receptors, CXCR3/metabolism
Czasopismo naukowe
Tytuł:
Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes.
Autorzy:
Christen U; Pharmazentrum Frankfurt, Goethe University Frankfurt, Germany.
Pouzol L; Immunology and Pharmacology Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Tunis M; Immunology and Pharmacology Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Sassi A; Immunology and Pharmacology Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Tondello C; Pharmazentrum Frankfurt, Goethe University Frankfurt, Germany.
Bayer M; Pharmazentrum Frankfurt, Goethe University Frankfurt, Germany.
Hintermann E; Pharmazentrum Frankfurt, Goethe University Frankfurt, Germany.
Strasser DS; Translational Biomarkers Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Schuldes S; Project Management Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Mentzel U; Pharmacology and Preclinical Development Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
Martinic MM; Immunology and Pharmacology Department, Idorsia Pharmaceuticals Ltd., Hegenheimermattweg 91, Allschwil, Switzerland.
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Źródło:
Clinical and experimental immunology [Clin Exp Immunol] 2023 Dec 12; Vol. 214 (2), pp. 131-143.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 1*
Humans ; Mice ; Animals ; Mice, Inbred NOD ; Blood Glucose ; C-Peptide ; Antibodies, Monoclonal/therapeutic use ; Models, Theoretical ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
CXCL9 and its Receptor CXCR3, an Important Link Between Inflammation and Cardiovascular Risks in RA Patients.
Autorzy:
Shamsi A; Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Roghani SA; Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Abdan Z; Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Soufivand P; Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Pournazari M; Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Bahrehmand F; Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Vafaei A; Department of Medical Biotechnology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Salari N; Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.; Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Soroush MG; Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Taghadosi M; Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. .
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Źródło:
Inflammation [Inflammation] 2023 Dec; Vol. 46 (6), pp. 2374-2385. Date of Electronic Publication: 2023 Aug 05.
Typ publikacji:
Journal Article
MeSH Terms:
Cardiovascular Diseases*/diagnosis
Cardiovascular Diseases*/etiology
Arthritis, Rheumatoid*/metabolism
Humans ; Risk Factors ; Chemokine CXCL9 ; Inflammation ; Heart Disease Risk Factors ; Receptors, CXCR3/metabolism ; Chemokine CXCL10
Czasopismo naukowe
Tytuł:
Identification and Characterization of CD8 T Cell Dysregulation and Progression-Associated Biomarkers in Systemic Lupus Erythematosus.
Autorzy:
Zhang L; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
Du F; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
Jin Q; Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 200031, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Sun L; Department of Rheumatology and Immunology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, China.
Wang B; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
Tan Z; Science for Life Laboratory, Department of Women's and Children's Health, Karolinska Institutet, Solna, 17121, Sweden.
Meng X; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
Huang B; Department of Chemical Pathology, Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, 999077, China.
Zhan Y; Drug Discovery, Shanghai Huaota Biopharmaceutical Co. Ltd., Shanghai, 200131, China.
Su W; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
Song R; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.; Nantong First People's Hospital, Affiliated Hospital 2 of Nantong University, Nantong Hospital of Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine.
Wu C; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.
Chen L; Key Laboratory of Systems Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 200031, China.; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Hangzhou, 310024, China.
Chen X; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.
Ding X; Department of Rheumatology, Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering, Shanghai, 200030, China.; State Key Laboratory of Oncogenes and Related Genes, Institute for Personalized Medicine, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200001, China.
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Źródło:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2023 Dec; Vol. 10 (35), pp. e2300123. Date of Electronic Publication: 2023 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*
Lupus Erythematosus, Systemic*/diagnosis
Humans ; CD8-Positive T-Lymphocytes ; Leukocytes, Mononuclear ; Biomarkers ; Disease Progression ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts.
Autorzy:
Reijm S
Kwekkeboom JC
Blomberg NJ
Suurmond J
van der Woude D
Toes RE
Scherer HU
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Źródło:
JCI insight [JCI Insight] 2023 Oct 23; Vol. 8 (20). Date of Electronic Publication: 2023 Oct 23.
Typ publikacji:
Journal Article
MeSH Terms:
Memory B Cells*
Arthritis, Rheumatoid*
Humans ; B-Lymphocytes ; Plasma Cells ; Autoantibodies ; Antigens ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Interferon-γ production by Tfh cells is required for CXCR3 pre-memory B cell differentiation and subsequent lung-resident memory B cell responses.
Autorzy:
Arroyo-Díaz NM; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Bachus H; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Papillion A; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Randall TD; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Akther J; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Rosenberg AF; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, USA; Informatics Institute, The University of Alabama at Birmingham, Birmingham, AL, USA.
León B; Department of Microbiology, The University of Alabama at Birmingham, Birmingham, AL, USA.
Ballesteros-Tato A; Department of Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: .
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Źródło:
Immunity [Immunity] 2023 Oct 10; Vol. 56 (10), pp. 2358-2372.e5. Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
T-Lymphocytes, Helper-Inducer*
Influenza, Human*
Humans ; Interferon-gamma/metabolism ; Memory B Cells ; T Follicular Helper Cells/metabolism ; Germinal Center ; Cell Differentiation ; Receptors, CXCR3/metabolism
Czasopismo naukowe
Tytuł:
Keras/TensorFlow in Drug Design for Immunity Disorders.
Autorzy:
Dragan P; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-903 Warsaw, Poland.
Joshi K; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-903 Warsaw, Poland.
Atzei A; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-903 Warsaw, Poland.; Department of Life and Environmental Science, Food Toxicology Unit, University of Cagliari, University Campus of Monserrato, SS 554, 09042 Cagliari, Italy.
Latek D; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-903 Warsaw, Poland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 09; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 09.
Typ publikacji:
Journal Article
MeSH Terms:
Chemokines*/metabolism
Cytokines*/pharmacology
Receptors, Chemokine/metabolism ; Chemotaxis ; Drug Design ; Receptors, CXCR3
Czasopismo naukowe
Tytuł:
Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis.
Autorzy:
Wang X; Department of General Practice, Xiangya Hospital, Central South University, Changsha, Hunan, China.; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Richard ML; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Caldwell TS; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Sundararaj K; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Sato S; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan.
Nowling TK; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
Zhang XK; Department of Medicine, Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, United States.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Sep 15; Vol. 14, pp. 1219279. Date of Electronic Publication: 2023 Sep 15 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelial Cells*/metabolism
Proto-Oncogene Protein c-fli-1*/genetics
Proto-Oncogene Protein c-fli-1*/metabolism
Animals ; Humans ; Mice ; Chemokine CXCL10/genetics ; Chemokine CXCL10/metabolism ; Kidney/pathology ; Mice, Inbred MRL lpr ; Receptors, CXCR3/genetics ; Receptors, CXCR3/metabolism
Czasopismo naukowe

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