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Tytuł :
Vitamin D pathway related polymorphisms and vitamin D receptor expression in breast cancer.
Autorzy :
Francis I; Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
AlAbdali N; Postgraduate Medical Sciences Program, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
Kapila K; Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
John B; Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
Al-Temaimi RA; Department of Pathology, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
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Źródło :
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition [Int J Vitam Nutr Res] 2021 Jan; Vol. 91 (1-2), pp. 124-132. Date of Electronic Publication: 2019 Oct 18.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms*/genetics
Receptors, Calcitriol*/genetics
Case-Control Studies ; Female ; Genetic Predisposition to Disease ; Genotype ; Humans ; Polymorphism, Single Nucleotide ; Vitamin D
Czasopismo naukowe
Tytuł :
Molecular determinants of MED1 interaction with the DNA bound VDR-RXR heterodimer.
Autorzy :
Belorusova AY; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Centre National de la Recherche Scientifique UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Bourguet M; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS UMR 7178, IPHC, Strasbourg, France.
Hessmann S; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS UMR 7178, IPHC, Strasbourg, France.
Chalhoub S; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Centre National de la Recherche Scientifique UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Kieffer B; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Centre National de la Recherche Scientifique UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Cianférani S; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS UMR 7178, IPHC, Strasbourg, France.
Rochel N; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Illkirch, France.; Centre National de la Recherche Scientifique UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2020 Nov 04; Vol. 48 (19), pp. 11199-11213.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mediator Complex Subunit 1*/chemistry
Mediator Complex Subunit 1*/metabolism
Receptors, Calcitriol*/chemistry
Receptors, Calcitriol*/metabolism
Retinoid X Receptor alpha*/chemistry
Retinoid X Receptor alpha*/metabolism
DNA/*metabolism
Humans ; Ligands ; Protein Binding ; Protein Domains ; Protein Multimerization
Czasopismo naukowe
Tytuł :
Placenta expression of vitamin D and related genes in pregnant women with gestational diabetes mellitus.
Autorzy :
Wang Y; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Wang T; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Huo Y; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China. Electronic address: .
Liu L; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Liu S; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Yin X; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Wang R; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
Gao X; Department of Obstetrics & Gynecology, Hebei General Hospital, Shijiazhuang 050051, China.
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2020 Nov; Vol. 204, pp. 105754. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
25-Hydroxyvitamin D3 1-alpha-Hydroxylase*/genetics
25-Hydroxyvitamin D3 1-alpha-Hydroxylase*/metabolism
Diabetes, Gestational*/genetics
Diabetes, Gestational*/metabolism
Receptors, Calcitriol*/genetics
Receptors, Calcitriol*/metabolism
Vitamin D3 24-Hydroxylase*/genetics
Vitamin D3 24-Hydroxylase*/metabolism
Placenta/*metabolism
Vitamin D/*metabolism
Adult ; DNA Methylation ; Female ; Fetal Blood/metabolism ; Gene Expression ; Humans ; Pregnancy ; Vitamin D/blood
Czasopismo naukowe
Tytuł :
Association between Gene Polymorphisms of Vitamin D Receptor and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Autorzy :
Zhou Q; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.; Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Wen S; OMNI Research Group, Ottawa Hospital Research Institute, Ottawa, ON K1H 8M5, Canada.; Department of Obstetrics and Gynaecology, School of Epidemiology and Public Health, University of Ottawa Faculty of Medicine, Ottawa, ON K1H 8M5, Canada.
Liu M; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.; Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Zhang S; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.; Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Jin X; Department of Maternal and Child Health, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Liu A; Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.; Hunan Provincial Key Laboratory of Clinical Epidemiology, Xiangya School of Public Health, Central South University, Changsha 410078, China.
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Źródło :
International journal of environmental research and public health [Int J Environ Res Public Health] 2020 Dec 29; Vol. 18 (1). Date of Electronic Publication: 2020 Dec 29.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Systematic Review
MeSH Terms :
Diabetes, Gestational*/epidemiology
Diabetes, Gestational*/genetics
Receptors, Calcitriol*/genetics
China ; Cross-Sectional Studies ; Female ; Genetic Predisposition to Disease ; Humans ; Polymorphism, Genetic ; Pregnancy ; Prospective Studies
Czasopismo naukowe
Tytuł :
Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia.
Autorzy :
Rovito D; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Belorusova AY; Medicinal Chemistry, Respiratory, Inflammation and Autoimmunity, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Chalhoub S; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Rerra AI; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Guiot E; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Molin A; Université de Normandie, UNICAEN, CHU de Caen Normandie, Service de Génétique, EA 7450 BIOTARGEN, Caen, France.; Reference Center for Rare Diseases of Calcium and Phosphorus Metabolism (OSCAR), Paris, France.
Linglart A; Reference Center for Rare Diseases of Calcium and Phosphorus Metabolism (OSCAR), Paris, France.; Université de Paris Saclay, AP-HP, Hôpital Bicêtre, DMU SEA, INSERM, U1185, Le Kremlin Bicêtre, France.
Rochel N; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France.; Université de Strasbourg, Illkirch, France.
Laverny G; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France. .; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France. .; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France. .; Université de Strasbourg, Illkirch, France. .
Metzger D; Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France. .; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France. .; Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Illkirch, France. .; Université de Strasbourg, Illkirch, France. .
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Źródło :
Nature communications [Nat Commun] 2020 Dec 07; Vol. 11 (1), pp. 6249. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcium/*metabolism
Hypercalcemia/*metabolism
Receptors, Calcitriol/*metabolism
Vitamin D/*pharmacology
Animals ; Calcitriol/analogs & derivatives ; Calcitriol/pharmacology ; Cell Line ; Cell Line, Tumor ; Cytosol/metabolism ; Gene Expression/drug effects ; HeLa Cells ; Humans ; Hypercalcemia/genetics ; Hypercalcemia/prevention & control ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Protein Binding ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Rats ; Receptors, Calcitriol/genetics ; Vitamin D/analogs & derivatives
Czasopismo naukowe
Tytuł :
Vitamin D and its receptor polymorphisms are associated with glaucoma.
Autorzy :
Ulhaq ZS; Department of Biochemistry, Faculty of Medicine and Health Sciences, Maulana Malik Ibrahim State Islamic University of Malang, 65151 Batu, East Java, Indonesia. Electronic address: .
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Źródło :
Journal francais d'ophtalmologie [J Fr Ophtalmol] 2020 Dec; Vol. 43 (10), pp. 1009-1019. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji :
Journal Article; Meta-Analysis
MeSH Terms :
Polymorphism, Single Nucleotide*
Glaucoma/*genetics
Receptors, Calcitriol/*genetics
Vitamin D/*genetics
Adult ; Aged ; Aged, 80 and over ; Case-Control Studies ; Deoxyribonucleases, Type II Site-Specific/metabolism ; Female ; Genetic Association Studies ; Genetic Predisposition to Disease ; Glaucoma/epidemiology ; Humans ; Male ; Middle Aged ; Polymorphism, Restriction Fragment Length/genetics ; Receptors, Calcitriol/metabolism ; Risk Factors ; Vitamin D/metabolism
Czasopismo naukowe
Tytuł :
Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing.
Autorzy :
Evans RM; Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: .
Lippman SM; Moores Cancer Center, UC San Diego School of Medicine, La Jolla, CA 92093, USA.
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Źródło :
Cell metabolism [Cell Metab] 2020 Nov 03; Vol. 32 (5), pp. 704-709. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Betacoronavirus*
Coronavirus Infections/*drug therapy
Drug Repositioning/*methods
Ergocalciferols/*pharmacology
Ergocalciferols/*therapeutic use
Pneumonia, Viral/*drug therapy
Receptors, Calcitriol/*agonists
Wound Healing/*drug effects
Animals ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Cytokines/metabolism ; Humans ; Mice ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/virology ; Receptors, Calcitriol/metabolism ; SARS-CoV-2 ; Vitamin D Deficiency/drug therapy ; Vitamin D Deficiency/epidemiology
Czasopismo naukowe
Tytuł :
The Vitamin D Receptor in Osteoblast-Lineage Cells Is Essential for the Proresorptive Activity of 1α,25(OH)2D3 In Vivo.
Autorzy :
Mori T; Graduate School of Oral Medicine, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Horibe K; Department of Oral Histology, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Koide M; Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Uehara S; Department of Biochemistry, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Yamamoto Y; Department of Surgical Oncology, The University of Tokyo, Tokyo, Japan.
Kato S; Research Institute of Innovative Medicine, Tokiwa Foundation, Iwaki, Fukushima, Japan.; Department of Basic Pathology, Fukushima Medical University, Fukushima, Japan.
Yasuda H; Nagahama Institute for Biochemical Science, Oriental Yeast Co., Ltd., Nagahama, Shiga, Japan.
Takahashi N; Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Udagawa N; Department of Biochemistry, Matsumoto Dental University, Shiojiri, Nagano, Japan.
Nakamichi Y; Institute for Oral Science, Matsumoto Dental University, Shiojiri, Nagano, Japan.
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Źródło :
Endocrinology [Endocrinology] 2020 Nov 01; Vol. 161 (11).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Resorption/*genetics
Cell Lineage/*genetics
Osteoblasts/*metabolism
Receptors, Calcitriol/*physiology
Vitamin D/*analogs & derivatives
Animals ; Bone Resorption/metabolism ; Bone and Bones/drug effects ; Bone and Bones/metabolism ; Female ; Hypercalcemia/genetics ; Hypercalcemia/metabolism ; Hypercalcemia/pathology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Obese ; Mice, Transgenic ; Obesity/genetics ; Obesity/metabolism ; Obesity/pathology ; Osteoblasts/cytology ; Receptors, Calcitriol/genetics ; Vitamin D/pharmacology
Czasopismo naukowe
Tytuł :
Cytoplasmic VDR expression as an independent risk factor for ovarian cancer.
Autorzy :
Czogalla B; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany. .
Deuster E; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Liao Y; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Mayr D; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Schmoeckel E; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Sattler C; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Kolben T; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Hester A; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Fürst S; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Burges A; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Mahner S; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
Jeschke U; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.; Department of Obstetrics and Gynecology, University Hospital Augsburg, Augsburg, Germany.
Trillsch F; Department of Obstetrics and Gynecology, University Hospital, LMU Munich, Marchioninistr 15, 81377, Munich, Germany.
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Źródło :
Histochemistry and cell biology [Histochem Cell Biol] 2020 Oct; Vol. 154 (4), pp. 421-429. Date of Electronic Publication: 2020 Jun 22.
Typ publikacji :
Journal Article
MeSH Terms :
Cytoplasm/*metabolism
Ovarian Neoplasms/*metabolism
Receptors, Calcitriol/*biosynthesis
Adult ; Aged ; Aged, 80 and over ; Cytoplasm/chemistry ; Female ; Humans ; Immunohistochemistry ; Middle Aged ; Ovarian Neoplasms/diagnosis ; Receptors, Calcitriol/analysis ; Risk Factors ; Staining and Labeling
Czasopismo naukowe
Tytuł :
Structural Analysis of VDR Complex with ZK168281 Antagonist.
Autorzy :
Belorusova AY; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch, France.; Institut National de La Santé et de La Recherche Médicale (INSERM), U1258, 67400 Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, 67400 Illkirch, France.; Université de Strasbourg, 67400 Illkirch, France.; Medicinal Chemistry, Early Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, 431 83 Gothenburg, Sweden.
Chalhoub S; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch, France.; Institut National de La Santé et de La Recherche Médicale (INSERM), U1258, 67400 Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, 67400 Illkirch, France.; Université de Strasbourg, 67400 Illkirch, France.
Rovito D; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch, France.; Institut National de La Santé et de La Recherche Médicale (INSERM), U1258, 67400 Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, 67400 Illkirch, France.; Université de Strasbourg, 67400 Illkirch, France.
Rochel N; Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67400 Illkirch, France.; Institut National de La Santé et de La Recherche Médicale (INSERM), U1258, 67400 Illkirch, France.; Centre National de Recherche Scientifique (CNRS), UMR7104, 67400 Illkirch, France.; Université de Strasbourg, 67400 Illkirch, France.
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Źródło :
Journal of medicinal chemistry [J Med Chem] 2020 Sep 10; Vol. 63 (17), pp. 9457-9463. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Calcitriol/*analogs & derivatives
Receptors, Calcitriol/*antagonists & inhibitors
Receptors, Calcitriol/*metabolism
Animals ; Calcitriol/metabolism ; Calcitriol/pharmacology ; Cell Line ; Ligands ; Models, Molecular ; Protein Binding ; Protein Domains ; Rats ; Receptors, Calcitriol/chemistry ; Zebrafish
Czasopismo naukowe
Tytuł :
Vitamin D receptor gene methylation in patients with hand, foot, and mouth disease caused by enterovirus 71.
Autorzy :
Li YP; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China.
Deng HL; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China.; Department of Infectious Diseases, Xi'an Children's Hospital, Xi'an, 710003, China.
Wang WJ; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China.
Wang MQ; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China.
Li M; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China.
Zhang YF; Department of Infectious Diseases, Xi'an Children's Hospital, Xi'an, 710003, China.
Wang J; Department of Infectious Diseases, Xi'an Children's Hospital, Xi'an, 710003, China.
Dang SS; Department of Infectious Diseases, Xi'an Jiaotong University Second Affiliated Hospital, No. 157 Xiwu Road, Xi'an, 710004, China. .
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Źródło :
Archives of virology [Arch Virol] 2020 Sep; Vol. 165 (9), pp. 1979-1985. Date of Electronic Publication: 2020 Jun 18.
Typ publikacji :
Journal Article
MeSH Terms :
Enterovirus A, Human/*physiology
Hand, Foot and Mouth Disease/*genetics
Receptors, Calcitriol/*genetics
Child ; Child, Preschool ; China ; Enterovirus A, Human/genetics ; Epigenesis, Genetic ; Female ; Hand, Foot and Mouth Disease/metabolism ; Hand, Foot and Mouth Disease/virology ; Humans ; Infant ; Male ; Methylation ; Promoter Regions, Genetic ; Receptors, Calcitriol/metabolism
Czasopismo naukowe
Tytuł :
TRAF3 Modulation: Novel Mechanism for the Anti-inflammatory Effects of the Vitamin D Receptor Agonist Paricalcitol in Renal Disease.
Autorzy :
Rayego-Mateos S; Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain.; Vascular and Renal Translational Research Group. Institut de Receca Biomedica de Lleida (IRBLleida), Lleida, Spain.
Morgado-Pascual JL; Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain.; REDinREN (Red de Investigación Renal), Madrid, Spain.
Valdivielso JM; Vascular and Renal Translational Research Group. Institut de Receca Biomedica de Lleida (IRBLleida), Lleida, Spain.; REDinREN (Red de Investigación Renal), Madrid, Spain.
Sanz AB; REDinREN (Red de Investigación Renal), Madrid, Spain.; Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
Bosch-Panadero E; Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
Rodrigues-Díez RR; Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain.
Egido J; Renal, Vascular and Diabetes Research Laboratory, IIS-Fundación Jiménez Díaz.Universidad Autónoma. 28040 Madrid, Spain; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM). 28029 Madrid, Spain.
Ortiz A; REDinREN (Red de Investigación Renal), Madrid, Spain.; Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
González-Parra E; Laboratory of Nephrology and Hypertension, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz-Universidad Autónoma Madrid, 28040 Madrid, Spain.
Ruiz-Ortega M; Molecular and Cellular Biology in Renal and Vascular Pathology, Fundación Instituto de Investigación Sanitaria-Fundación Jiménez Díaz,Universidad autonoma de madrid, Madrid, Spain .; REDinREN (Red de Investigación Renal), Madrid, Spain.
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Źródło :
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2020 Sep; Vol. 31 (9), pp. 2026-2042. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Inflammatory Agents/*pharmacology
Ergocalciferols/*pharmacology
Kidney Failure, Chronic/*drug therapy
Receptors, Calcitriol/*agonists
TNF Receptor-Associated Factor 3/*physiology
Animals ; Cells, Cultured ; Cytokine TWEAK/pharmacology ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; NF-kappa B/antagonists & inhibitors ; NF-kappa B/physiology ; Receptors, Calcitriol/physiology ; Signal Transduction/drug effects ; TNF Receptor-Associated Factor 3/analysis
Czasopismo naukowe
Tytuł :
Modified expression of vitamin D receptor and CYP27B1 in denervation-induced muscle atrophy.
Autorzy :
Mori R; Faculty of Sport and Health Science, Ritsumeikan University, Kusatsu, Shiga, Japan.
Yokokawa T; Research Organization of Science and Technology, Ritsumeikan University, Kusatsu, Shiga, Japan.
Fujita S; Faculty of Sport and Health Science, Ritsumeikan University, Kusatsu, Shiga, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Aug 27; Vol. 529 (3), pp. 733-739. Date of Electronic Publication: 2020 Jul 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/*analysis
Muscular Atrophy/*pathology
Receptors, Calcitriol/*analysis
25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism ; Animals ; Disease Models, Animal ; Male ; Mice, Inbred C57BL ; Muscle Denervation ; Muscular Atrophy/metabolism ; Proteasome Endopeptidase Complex/metabolism ; Receptors, Calcitriol/metabolism ; Signal Transduction ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł :
Association between vitamin D receptor gene polymorphisms ( Fok I, Cdx-2 ) and bone mineral density in Slovak postmenopausal women.
Autorzy :
Boroňová I; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Bernasovská J; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Mačeková S; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Kľoc J; Department of Orthopedics, Faculty Hospital of J.A.Reyman, Prešov, Slovakia.; Osteocentrum s.r.o., Osteological ambulance, Prešov, Slovakia.
Tomková Z; Osteocentrum s.r.o., Osteological ambulance, Prešov, Slovakia.
Bernasovský I; Center of Languages and Cultures of National Minorities, University of Prešov, Slovakia.
Šeliga P; Department of Vascular Surgery, Faculty Hospital of J.A.Reyman, Prešov, Slovakia.
Petrejčíková E; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Zigová M; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Blaščáková MM; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia.
Majherová M; Department of Physics, Mathematics and Techniques, University of Prešov, Slovakia.
Grejtáková D; Department of Biology, Faculty of Humanities and Natural Sciences, University of Prešov, Slovakia Department of Dental Hygiene, Faculty of Health Care, University of Prešov, Slovakia.
Klamárová T; Department of Dental Hygiene, Faculty of Health Care, University of Prešov, Slovakia.
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Źródło :
Anthropologischer Anzeiger; Bericht uber die biologisch-anthropologische Literatur [Anthropol Anz] 2020 Aug 12; Vol. 77 (3), pp. 195-203.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Density*
Polymorphism, Genetic*
Receptors, Calcitriol*/genetics
Adult ; Aged ; Aged, 80 and over ; Female ; Genotype ; Humans ; Middle Aged ; Postmenopause ; Slovakia
Czasopismo naukowe
Tytuł :
Downregulation of the Ca channel K Ca 3.1 in mouse preosteoblast cells treated with vitamin D receptor agonist.
Autorzy :
Kito H; Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Morihiro H; Department of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.
Sakakibara Y; Department of Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Kyoto, Japan.
Endo K; Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Kajikuri J; Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Suzuki T; Department of Complex Molecular Chemistry, The Institute of Scientific and Industrial Research, Osaka University, Osaka, Japan.
Ohya S; Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Aug 01; Vol. 319 (2), pp. C345-C358. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intermediate-Conductance Calcium-Activated Potassium Channels/*genetics
Osteoblasts/*metabolism
Receptors, Calcitriol/*genetics
Vitamin D/*genetics
3T3 Cells ; Animals ; Benzimidazoles/pharmacology ; Calcium/metabolism ; Calcium Signaling/genetics ; Cell Differentiation/drug effects ; Cell Proliferation/drug effects ; Gene Expression Regulation/genetics ; Histone Deacetylase 2/genetics ; Humans ; Mice ; Osteoblasts/cytology ; Osteogenesis/drug effects ; Osteogenesis/genetics ; Patch-Clamp Techniques ; Proto-Oncogene Proteins c-fos/genetics ; Receptors, Calcitriol/agonists ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
The impact of vitamin D supplementation on VDR gene expression and body composition in monozygotic twins: randomized controlled trial.
Autorzy :
Medeiros JFP; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil. .
de Oliveira Borges MV; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil.
Soares AA; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil.
Dos Santos JC; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.
de Oliveira ABB; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.
da Costa CHB; Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.
Cruz MS; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil.
Bortolin RH; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
de Freitas RCC; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Dantas PMS; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil.
Hirata MH; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil.
Silbiger VN; Graduate Program in Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.
Luchessi AD; Department of Health Sciences, Federal University of Rio Grande Do Norte, Av. General Cordeiro de Farias, S/N - Petrópolis, Natal, RN, 59012-570, Brazil.; Graduate Program in Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.; Department of Clinical and Toxicological Analyses, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 20; Vol. 10 (1), pp. 11943. Date of Electronic Publication: 2020 Jul 20.
Typ publikacji :
Journal Article; Randomized Controlled Trial; Twin Study
MeSH Terms :
Dietary Supplements*
Twins, Monozygotic*
Body Composition/*drug effects
Gene Expression Regulation/*drug effects
Receptors, Calcitriol/*genetics
Vitamin D/*administration & dosage
Adult ; Biomarkers ; Female ; Humans ; Male ; Receptors, Calcitriol/metabolism ; Skin ; Sunlight ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with retinoid X receptor.
Autorzy :
Fadel L; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Rehó B; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Volkó J; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Bojcsuk D; Department of Biochemistry and Molecular Biology, Doctoral School of Molecular Cell and Immune Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Kolostyák Z; Department of Biochemistry and Molecular Biology, Doctoral School of Molecular Cell and Immune Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Nagy G; Department of Biochemistry and Molecular Biology, Doctoral School of Molecular Cell and Immune Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Müller G; Biophysics of Macromolecules, German Cancer Research Center, Heidelberg, Germany.
Simandi Z; Department of Biochemistry and Molecular Biology, Doctoral School of Molecular Cell and Immune Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Hegedüs É; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Szabó G; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Tóth K; Biophysics of Macromolecules, German Cancer Research Center, Heidelberg, Germany.
Nagy L; Department of Biochemistry and Molecular Biology, Doctoral School of Molecular Cell and Immune Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary .; Johns Hopkins University School of Medicine, Department of Medicine and Biological Chemistry, Institute for Fundamental Biomedical Research, Johns Hopkins All Children's Hospital, Saint Petersburg, Florida, USA.
Vámosi G; Department of Biophysics and Cell Biology, Doctoral School of Molecular Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jul 17; Vol. 295 (29), pp. 10045-10061. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Multimerization*
PPAR gamma/*metabolism
Receptors, Calcitriol/*metabolism
Retinoic Acid Receptor alpha/*metabolism
Retinoid X Receptor alpha/*metabolism
HEK293 Cells ; Humans ; PPAR gamma/genetics ; Receptors, Calcitriol/genetics ; Retinoic Acid Receptor alpha/genetics ; Retinoid X Receptor alpha/genetics
Czasopismo naukowe
Tytuł :
Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications.
Autorzy :
El-Sharkawy A; Human Molecular Genetics Laboratory, Institute of Genetics and Biophysics 'A. Buzzati-Traverso' (IGB)-CNR, 80131 Naples, Italy.; Biomolecular Science Programme, Università Degli Studi Della Campania 'Luigi Vanvitelli', Viale Abramo Lincoln, 5, 81100 Caserta, Italy.
Malki A; Biomedical Science Department, College of Health Sciences, QU Health, Qatar University, Doha 2713, Qatar.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2020 Jul 15; Vol. 25 (14). Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Receptors, Calcitriol*/metabolism
Signal Transduction*
Inflammation/*etiology
Inflammation/*metabolism
Neoplasms/*etiology
Neoplasms/*metabolism
Vitamin D/*metabolism
Animals ; Disease Management ; Disease Susceptibility ; Humans ; Inflammation/epidemiology ; Metabolic Networks and Pathways ; Neoplasms/epidemiology
Czasopismo naukowe
Tytuł :
RNA-binding protein HuR regulates translation of vitamin D receptor modulating rapid epithelial restitution after wounding.
Autorzy :
Zhang Y; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Cai JZ; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Xiao L; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Chung HK; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Ma XX; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Chen LL; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Rao JN; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.
Wang JY; Cell Biology Group, Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland.; Baltimore Veterans Affairs Medical Center, Baltimore, Maryland.; Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2020 Jul 01; Vol. 319 (1), pp. C208-C217. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
ELAV-Like Protein 1/*metabolism
Epithelial Cells/*metabolism
Intestinal Mucosa/*injuries
Intestinal Mucosa/*metabolism
Protein Biosynthesis/*physiology
Receptors, Calcitriol/*metabolism
Animals ; ELAV-Like Protein 1/genetics ; Female ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Organoids/injuries ; Organoids/metabolism ; Rats ; Receptors, Calcitriol/genetics
Czasopismo naukowe
Tytuł :
Immunohistochemical expression of vitamin D receptor and forkhead box P3 in classic Hodgkin lymphoma: correlation with clinical and pathologic findings.
Autorzy :
Gupta GK; Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA. .; Department of Laboratory Medicine, Yale School of Medicine, 333 Cedar Street, New Haven, CT, 06520, USA. .
Agrawal T; Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA.; Department of Pathology and Laboratory Medicine, University of Rochester, Rochester, NY, USA.
Pilichowska M; Department of Pathology and Laboratory Medicine, Tufts Medical Center, Boston, MA, USA.
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Źródło :
BMC cancer [BMC Cancer] 2020 Jun 08; Vol. 20 (1), pp. 535. Date of Electronic Publication: 2020 Jun 08.
Typ publikacji :
Journal Article
MeSH Terms :
Biomarkers, Tumor/*metabolism
Forkhead Transcription Factors/*metabolism
Hodgkin Disease/*pathology
Receptors, Calcitriol/*metabolism
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/analysis ; Bone Marrow/pathology ; Child ; Child, Preschool ; Female ; Follow-Up Studies ; Forkhead Transcription Factors/analysis ; Hodgkin Disease/mortality ; Hodgkin Disease/therapy ; Humans ; Immunohistochemistry ; Lymph Nodes/cytology ; Lymph Nodes/pathology ; Male ; Middle Aged ; Prognosis ; Receptors, Calcitriol/analysis ; Reed-Sternberg Cells/metabolism ; Reed-Sternberg Cells/pathology ; Sex Factors ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Treatment Outcome ; Tumor Microenvironment ; Young Adult
Czasopismo naukowe

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