Temat: "Receptors, Eicosanoid" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: 5-Oxo-ETE/OXER1: A Link between Tumor Cells and Macrophages Leading to Regulation of Migration.
Autorzy:: Kalyvianaki K; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Salampasi EM; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Katsoulieris EN; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Boukla E; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Vogiatzoglou AP; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Notas G; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Castanas E; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.
Kampa M; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, 71500 Heraklion, Greece.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Dec 31; Vol. 29 (1). Date of Electronic Publication: 2023 Dec 31.
Typ publikacji:: Journal Article
MeSH Terms:: Arachidonic Acids*
Breast Neoplasms*
Humans ; Male ; Macrophages ; Arachidonic Acid ; Testosterone ; Receptors, Eicosanoid

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Skocz do pozycji: 2.

Tytuł:: Novel highly potent OXE receptor antagonists with prolonged plasma lifetimes that are converted to active metabolites in vivo in monkeys.
Autorzy:: Ye Q; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
Chourey S; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
Reddy CN; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
Wang R; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
Cossette C; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.
Gravel S; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.
Slobodchikova I; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, Montreal, QC, Canada.
Vuckovic D; Department of Chemistry and Biochemistry and PERFORM Centre, Concordia University, Montreal, QC, Canada.
Rokach J; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida.
Powell WS; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, QC, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2020 Jan; Vol. 177 (2), pp. 388-401. Date of Electronic Publication: 2020 Jan 17.
Typ publikacji:: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Anti-Allergic Agents/*pharmacokinetics
Anti-Inflammatory Agents/*pharmacokinetics
Indoles/*pharmacokinetics
Neutrophils/*drug effects
Receptors, Eicosanoid/*antagonists & inhibitors
Activation, Metabolic ; Administration, Oral ; Animals ; Anti-Allergic Agents/blood ; Anti-Allergic Agents/chemical synthesis ; Anti-Inflammatory Agents/blood ; Anti-Inflammatory Agents/chemical synthesis ; Calcium/metabolism ; Female ; Half-Life ; Humans ; Hydroxylation ; Indoles/blood ; Indoles/chemical synthesis ; Macaca fascicularis ; Neutrophils/metabolism ; Receptors, Eicosanoid/metabolism ; Structure-Activity Relationship

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Skocz do pozycji: 3.

Tytuł:: Inhibition of allergen-induced dermal eosinophilia by an oxoeicosanoid receptor antagonist in non-human primates.
Autorzy:: Miller LA; California National Primate Research Center, University of California, Davis, California, USA.
Cossette C; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, Quebec, Canada.
Chourey S; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.; Department of Chemical Development, Albany Molecular Research Inc., Albany, New York.
Ye Q; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.; Department of Chemistry, Rice University, Houston, Texas.
Reddy CN; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.; Synthetic Chemistry, Olon Ricerca Bioscience LLC, Concord, Ohio.
Rokach J; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.
Powell WS; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, Quebec, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2020 Jan; Vol. 177 (2), pp. 360-371. Date of Electronic Publication: 2020 Jan 17.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Allergens*
Anti-Allergic Agents/*pharmacology
Chemotaxis, Leukocyte/*drug effects
Dermatitis/*prevention & control
Eosinophilia/*prevention & control
Eosinophils/*drug effects
Receptors, Eicosanoid/*antagonists & inhibitors
Skin/*drug effects
Animals ; Anti-Allergic Agents/chemical synthesis ; Anti-Allergic Agents/pharmacokinetics ; Antigens, Helminth/immunology ; Arachidonic Acids ; Ascaris suum/immunology ; Cells, Cultured ; Dermatitis/immunology ; Dermatitis/metabolism ; Disease Models, Animal ; Eosinophilia/immunology ; Eosinophilia/metabolism ; Eosinophils/immunology ; Eosinophils/metabolism ; Insect Proteins/immunology ; Macaca fascicularis ; Macaca mulatta ; Male ; Pilot Projects ; Pyroglyphidae/immunology ; Receptors, Eicosanoid/metabolism ; Signal Transduction ; Skin/immunology ; Skin/metabolism

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Skocz do pozycji: 4.

Tytuł:: The affinity, intrinsic activity and selectivity of a structurally novel EP 2 receptor agonist at human prostanoid receptors.
Autorzy:: Coleman RA; Asterand Bioscience, Royston, UK.
Woodrooffe AJ; Asterand Bioscience, Royston, UK.
Clark KL; Asterand Bioscience, Royston, UK.
Toris CB; University of Nebraska Medical Center, Omaha, NE, USA.
Fan S; University of Nebraska Medical Center, Omaha, NE, USA.
Wang JW; JeniVision Inc., Irvine, CA, USA.
Woodward DF; JeniVision Inc., Irvine, CA, USA.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2019 Mar; Vol. 176 (5), pp. 687-698. Date of Electronic Publication: 2019 Jan 04.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Eicosanoid/*agonists
Animals ; Anti-Inflammatory Agents/pharmacology ; Female ; Humans ; Interleukin-2/metabolism ; Intraocular Pressure/drug effects ; Leukocytes, Mononuclear/metabolism ; Macaca fascicularis ; Myometrium/drug effects ; Myometrium/physiology ; Pregnancy ; Receptors, Eicosanoid/metabolism ; Receptors, Eicosanoid/physiology ; Tocolytic Agents/pharmacology ; Tumor Necrosis Factor-alpha/metabolism

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Skocz do pozycji: 5.

Tytuł:: Targeting the OXE receptor with a selective antagonist inhibits allergen-induced pulmonary inflammation in non-human primates.
Autorzy:: Cossette C; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, Quebec, Canada.
Miller LA; California National Primate Research Center, University of California, Davis, California, USA.
Ye Q; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.
Chourey S; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.
Reddy CN; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.
Rokach J; Claude Pepper Institute and Department of Chemistry, Florida Institute of Technology, Melbourne, Florida, USA.
Powell WS; Meakins-Christie Laboratories, Centre for Translational Biology, McGill University Health Centre, Montreal, Quebec, Canada.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Jan; Vol. 179 (2), pp. 322-336. Date of Electronic Publication: 2021 Dec 16.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Asthma*/drug therapy
Pneumonia*/drug therapy
Pneumonia*/prevention & control
Allergens ; Animals ; Eosinophils ; Primates ; Receptors, Eicosanoid

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Skocz do pozycji: 6.

Tytuł:: Antagonizing effects of membrane-acting androgens on the eicosanoid receptor OXER1 in prostate cancer.
Autorzy:: Kalyvianaki K; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Gebhart V; Institute of Anatomy II, University Hospital Jena, Germany.
Peroulis N; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Panagiotopoulou C; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Kiagiadaki F; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Pediaditakis I; Department of Pharmacology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.; Institute of Molecular Biology &Biotechnology, Foundation of Research &Technology-Hellas (IMBB-FORTH), Heraklion, Greece.
Aivaliotis M; Proteomics Facility at Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology-Hellas, Heraklion, Crete.
Moustou E; Department of Pathology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Tzardi M; Department of Pathology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Notas G; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Castanas E; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.
Kampa M; Laboratory of Experimental Endocrinology, School of Medicine, University of Crete, Heraklion, GR-71003, Greece.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2017 Mar 14; Vol. 7, pp. 44418. Date of Electronic Publication: 2017 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Androgens/*chemistry
Cell Proliferation/*genetics
Prostatic Neoplasms/*genetics
Receptors, Eicosanoid/*chemistry
Androgens/genetics ; Arachidonic Acid/metabolism ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Humans ; Male ; Molecular Docking Simulation ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Receptors, Eicosanoid/genetics ; Testosterone/chemistry ; Testosterone/genetics

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Skocz do pozycji: 7.

Tytuł:: Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7.
Autorzy:: Bäck M; Nomenclature Subcommittee for Leukotriene Receptors, International Union of Basic and Clinical Pharmacology, Stockholm, Sweden; Department of Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Powell WS
Dahlén SE
Drazen JM
Evans JF
Serhan CN
Shimizu T
Yokomizo T
Rovati GE; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2014 Aug; Vol. 171 (15), pp. 3551-74. Date of Electronic Publication: 2014 Jul 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Receptors, Eicosanoid/*metabolism
Animals ; Humans ; Ligands ; Receptors, Eicosanoid/agonists ; Receptors, Eicosanoid/antagonists & inhibitors ; Signal Transduction