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    Tytuł:
    Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes.
    Autorzy:
    Rafii P; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Seibel C; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Weitz HT; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Ettich J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Minafra AR; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Petzsch P; Biological and Medical Research Center (BMFZ), Medical Faculty, Heinrich-Heine-University, Universitätsstraße 1, 40225, Duesseldorf, Germany.
    Lang A; Cardiovascular Research Laboratory, Medical Faculty, University Hospital Düsseldorf, 40225, Düsseldorf, Germany.
    Floss DM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Behnke K; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Köhrer K; Cardiovascular Research Laboratory, Medical Faculty, University Hospital Düsseldorf, 40225, Düsseldorf, Germany.
    Moll JM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
    Scheller J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany. .
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    Źródło:
    Communications biology [Commun Biol] 2023 Apr 15; Vol. 6 (1), pp. 418. Date of Electronic Publication: 2023 Apr 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-11*/genetics
    Hepatectomy*
    Mice ; Animals ; Humans ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Receptors, Interleukin-11 ; Antigens, CD/metabolism ; Interleukin-6/metabolism ; Signal Transduction ; Leukemia Inhibitory Factor Receptor alpha Subunit
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of IL-11/IL-11 Receptor Alpha on Proliferation and Steroidogenesis in Ovarian Granulosa Cells of Dairy Cows.
    Autorzy:
    Wu H; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
    Sun P; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
    Lv C; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
    Zhao X; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
    Liu M; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
    Zhou Q; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
    Tang J; College of Veterinary Medicine, Northwest A&F University, Xianyang 712100, China.
    Yang L; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.; National Center for International Research on Animal Genetics, Breeding and Reproduction, Huazhong Agricultural University, Wuhan 430070, China.
    Liang A; Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.; National Center for International Research on Animal Genetics, Breeding and Reproduction, Huazhong Agricultural University, Wuhan 430070, China.
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    Źródło:
    Cells [Cells] 2023 Feb 20; Vol. 12 (4). Date of Electronic Publication: 2023 Feb 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-11*
    Granulosa Cells*/metabolism
    Female ; Cattle ; Animals ; Progesterone/pharmacology ; Cell Proliferation/physiology ; Receptors, Interleukin-11/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The Interleukin-11/IL-11 Receptor Promotes Glioblastoma Survival and Invasion under Glucose-Starved Conditions through Enhanced Glutaminolysis.
    Autorzy:
    Stuart SF; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.; Fiona Elsey Cancer Research Institute, Ballarat, VIC 3350, Australia.
    Bezawork-Geleta A; Department of Physiology, The University of Melbourne, Melbourne, VIC 3010, Australia.
    Areeb Z; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Gomez J; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Tsui V; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Zulkifli A; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Paradiso L; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Jones J; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.; Department of Neurosurgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
    Nguyen HPT; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Putoczki TL; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3050, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
    Licciardi PV; Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia.; Department of Paediatrics, The University of Melbourne, Melbourne, VIC 3052, Australia.
    Kannourakis G; Fiona Elsey Cancer Research Institute, Ballarat, VIC 3350, Australia.; Health, Innovation and Transformation Centre, Federation University, Ballarat, VIC 3350, Australia.
    Morokoff AP; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.; Department of Neurosurgery, The Royal Melbourne Hospital, Parkville, VIC 3050, Australia.
    Achuthan AA; Department of Medicine, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.
    Luwor RB; Department of Surgery, The Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.; Fiona Elsey Cancer Research Institute, Ballarat, VIC 3350, Australia.; Health, Innovation and Transformation Centre, Federation University, Ballarat, VIC 3350, Australia.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Feb 08; Vol. 24 (4). Date of Electronic Publication: 2023 Feb 08.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Glioblastoma*/metabolism
    Humans ; Cell Line ; Cell Line, Tumor ; Glucose/metabolism ; Interleukin-11/metabolism ; Receptors, Interleukin-11
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP.
    Autorzy:
    Sammel M; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany.
    Peters F; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany.
    Lokau J; Institute of Pathology, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
    Scharfenberg F; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany.
    Werny L; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany.
    Linder S; Institute for Medical Microbiology, Virology and Hygiene, University Medical Center Eppendorf, 20246, Hamburg, Germany.
    Garbers C; Institute of Pathology, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany.
    Rose-John S; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany.
    Becker-Pauly C; Institute of Biochemistry, University of Kiel, Otto-Hahn-Platz 9, 24118 Kiel, Germany. .
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2019 Jul 26; Vol. 20 (15). Date of Electronic Publication: 2019 Jul 26.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    ADAM Proteins/*metabolism
    Matrix Metalloproteinase 14/*metabolism
    Metalloendopeptidases/*metabolism
    Receptors, Interleukin-11/*metabolism
    ADAM Proteins/chemistry ; Humans ; Matrix Metalloproteinase 14/chemistry ; Metalloendopeptidases/chemistry ; Phosphorylation ; Proteolysis ; Receptors, Interleukin-11/chemistry ; Receptors, Interleukin-6/metabolism ; STAT3 Transcription Factor/metabolism ; Signal Transduction ; Structure-Activity Relationship
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway.
    Autorzy:
    Tao L; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Huang G; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Wang R; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Pan Y; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    He Z; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Chu X; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Song H; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
    Chen L; Medical Oncology Department of Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002 People's Republic of China.
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    Źródło:
    Scientific reports [Sci Rep] 2016 Dec 06; Vol. 6, pp. 38408. Date of Electronic Publication: 2016 Dec 06.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Adenocarcinoma/*genetics
    Antineoplastic Agents/*pharmacology
    Cancer-Associated Fibroblasts/*drug effects
    Cisplatin/*pharmacology
    Interleukin-11/*metabolism
    Lung Neoplasms/*genetics
    Receptors, Interleukin-11/*metabolism
    STAT3 Transcription Factor/*metabolism
    A549 Cells ; Adenocarcinoma/drug therapy ; Adenocarcinoma/mortality ; Adenocarcinoma/pathology ; Adenocarcinoma of Lung ; Animals ; Cancer-Associated Fibroblasts/metabolism ; Cancer-Associated Fibroblasts/pathology ; Cell Communication/drug effects ; Cell Line, Tumor ; Drug Resistance, Neoplasm/genetics ; Female ; Humans ; Interleukin-11/genetics ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Phenanthrenes/pharmacology ; Phosphorylation/drug effects ; Primary Cell Culture ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Receptors, Interleukin-11/antagonists & inhibitors ; Receptors, Interleukin-11/genetics ; STAT3 Transcription Factor/genetics ; Signal Transduction ; Survival Analysis ; Xenograft Model Antitumor Assays
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models.
    Autorzy:
    Lim WW; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Corden B; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, W12 0NN, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.
    Ng B; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Vanezis K; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, W12 0NN, UK.; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK.
    D'Agostino G; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Song WH; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Xie C; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Su L; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Kwek XY; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Tee NGZ; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Dong J; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Ko NSJ; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Wang M; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Pua CJ; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Jamal MH; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Soh B; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.
    Viswanathan S; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Schafer S; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore.; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore.
    Cook SA; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, 169609, Singapore. .; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore, 169857, Singapore. .; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London, W12 0NN, UK. .; National Heart and Lung Institute, Imperial College London, London, SW3 6LY, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Oct 20; Vol. 10 (1), pp. 17853. Date of Electronic Publication: 2020 Oct 20.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Models, Animal*
    Phenotype*
    Aorta/*pathology
    Interleukin-11/*physiology
    Muscle, Smooth, Vascular/*pathology
    Vascular Remodeling/*physiology
    Animals ; Antibodies, Neutralizing/immunology ; Aorta/physiopathology ; Fibrosis ; Interleukin-11/immunology ; Mice ; Receptors, Interleukin-11/genetics ; Receptors, Interleukin-11/immunology ; Transforming Growth Factor beta1/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation.
    Autorzy:
    Lokau J; Institute of Biochemistry, Kiel University, 24118 Kiel, Germany.
    Agthe M; Institute of Biochemistry, Kiel University, 24118 Kiel, Germany.
    Garbers C; Institute of Biochemistry, Kiel University, 24118 Kiel, Germany.
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    Źródło:
    Mediators of inflammation [Mediators Inflamm] 2016; Vol. 2016, pp. 1785021. Date of Electronic Publication: 2016 Jul 14.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Receptors, Interleukin-11/*metabolism
    Receptors, Interleukin-6/*metabolism
    Animals ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Interleukin-11/metabolism ; Interleukin-6/metabolism ; Receptors, Interleukin-11/genetics ; Receptors, Interleukin-6/genetics ; Signal Transduction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Treating osteosarcoma with CAR T cells.
    Autorzy:
    Köksal H; Laboratory of Translational Research & Immunomonitoring, Section for Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.
    Müller E; Laboratory of Translational Research & Immunomonitoring, Section for Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.
    Inderberg EM; Laboratory of Translational Research & Immunomonitoring, Section for Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.
    Bruland Ø; Department of Oncology, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
    Wälchli S; Laboratory of Translational Research & Immunomonitoring, Section for Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.
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    Źródło:
    Scandinavian journal of immunology [Scand J Immunol] 2019 Mar; Vol. 89 (3), pp. e12741. Date of Electronic Publication: 2019 Jan 15.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Bone Neoplasms/*therapy
    Immunotherapy, Adoptive/*methods
    Osteosarcoma/*therapy
    Bone Neoplasms/immunology ; Bone Neoplasms/mortality ; Cancer-Associated Fibroblasts/physiology ; Endopeptidases ; Gangliosides/antagonists & inhibitors ; Gelatinases/physiology ; Humans ; Membrane Proteins/physiology ; Osteosarcoma/immunology ; Osteosarcoma/mortality ; Receptor, ErbB-2/analysis ; Receptor, IGF Type 1/physiology ; Receptors, Interleukin-11/antagonists & inhibitors ; Serine Endopeptidases/physiology ; Tumor Microenvironment
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    GM-CSF and IL-4 are not involved in IVIG-mediated amelioration of ITP in mice: a role for IL-11 cannot be ruled out.
    Autorzy:
    Lewis BJB; Department of Laboratory Medicine and Pathobiology, University of Toronto.; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
    Leontyev D; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
    Neschadim A; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
    Blacquiere M; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
    Branch DR; Department of Laboratory Medicine and Pathobiology, University of Toronto.; Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
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    Źródło:
    Clinical and experimental immunology [Clin Exp Immunol] 2018 Sep; Vol. 193 (3), pp. 293-301.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Granulocyte-Macrophage Colony-Stimulating Factor/*metabolism
    Interleukin-11/*metabolism
    Interleukin-4/*metabolism
    Purpura, Thrombocytopenic, Idiopathic/*immunology
    Animals ; Antibodies/administration & dosage ; Blood Platelets/immunology ; Cells, Cultured ; Disease Models, Animal ; Female ; Granulocyte-Macrophage Colony-Stimulating Factor/genetics ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Purpura, Thrombocytopenic, Idiopathic/therapy ; Receptors, Interleukin-11/genetics ; Receptors, Interleukin-4/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Expression, Purification, and Characterization of Interleukin-11 Orthologues.
    Autorzy:
    Sokolov AS; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Kazakov AS; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Solovyev VV; Biocad, Lubuchany 142380, Moscow Region, Russia. .
    Ismailov RG; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. ismailov_.
    Uversky VN; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .; Department of Molecular Medicine and USF Health Byrd Alzheimer's Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL 33612, USA. .
    Lapteva YS; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Mikhailov RV; Antherix, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Pavlova EV; Antherix, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Terletskaya IO; Antherix, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Ermolina LV; JSC R-Pharm, Berzarina str., 19/1, Moscow 123154, Russia. .
    Permyakov SE; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
    Permyakov EA; Institute for Biological Instrumentation of the Russian Academy of Sciences, Institutskaya str., 7, Pushchino 142290, Moscow Region, Russia. .
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2016 Nov 29; Vol. 21 (12). Date of Electronic Publication: 2016 Nov 29.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Interleukin-11/*metabolism
    Receptors, Interleukin-11/*metabolism
    STAT3 Transcription Factor/*metabolism
    Signal Transduction/*physiology
    Animals ; Cell Line ; Cloning, Molecular ; Enzyme Activation ; Escherichia coli/genetics ; Escherichia coli/metabolism ; HEK293 Cells ; Humans ; Interleukin-11/analysis ; Interleukin-11/genetics ; Interleukin-6/metabolism ; Macaca fascicularis ; Mice ; Recombinant Proteins/chemical synthesis ; Recombinant Proteins/genetics ; Species Specificity
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Optimal attenuation of experimental autoimmune encephalomyelitis by intravenous immunoglobulin requires an intact interleukin-11 receptor.
    Autorzy:
    Figueiredo CA; Research & Development, Canadian Blood Services, 67 College Toronto, Toronto, Ontario, Canada; Departments of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario, Canada.
    Drohomyrecky PC; Department of Immunology, University of Toronto, and Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada.
    McCarthy SD; Research & Development, Canadian Blood Services, 67 College Toronto, Toronto, Ontario, Canada; Departments of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario, Canada.
    Leontyev D; Research & Development, Canadian Blood Services, 67 College Toronto, Toronto, Ontario, Canada.
    Ma XZ; Research & Development, Canadian Blood Services, 67 College Toronto, Toronto, Ontario, Canada.
    Branch DR; Research & Development, Canadian Blood Services, 67 College Toronto, Toronto, Ontario, Canada; Departments of Laboratory Medicine and Pathobiology, University Health Network, Toronto, Ontario, Canada; Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.
    Dunn SE; Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada; Department of Immunology, University of Toronto, and Centre for Innovation, Canadian Blood Services, Toronto, Ontario, Canada; Women's College Research Institute, Toronto, Ontario, Canada.
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    Źródło:
    PloS one [PLoS One] 2014 Jul 31; Vol. 9 (7), pp. e101947. Date of Electronic Publication: 2014 Jul 31 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Encephalomyelitis, Autoimmune, Experimental/*prevention & control
    Immunoglobulins, Intravenous/*therapeutic use
    Receptors, Interleukin-11/*physiology
    Animals ; Interleukin-11/blood ; Interleukin-17/antagonists & inhibitors ; Interleukin-17/biosynthesis ; Mice ; T-Lymphocytes/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Sod1 deficiency reduces incubation time in mouse models of prion disease.
    Autorzy:
    Akhtar S; Medical Research Council Prion Unit and Department of Neurodegenerative Disease, University College London Institute of Neurology, London, United Kingdom.
    Grizenkova J
    Wenborn A
    Hummerich H
    Fernandez de Marco M
    Brandner S
    Collinge J
    Lloyd SE
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    Źródło:
    PloS one [PLoS One] 2013; Vol. 8 (1), pp. e54454. Date of Electronic Publication: 2013 Jan 22.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Genetic Association Studies*
    Prion Diseases/*genetics
    Superoxide Dismutase/*genetics
    Amyloid beta-Protein Precursor/genetics ; Animals ; Disease Models, Animal ; Humans ; Mice ; Polymorphism, Single Nucleotide ; Prion Diseases/physiopathology ; Quantitative Trait Loci/genetics ; Receptors, Interleukin-11/genetics ; Superoxide Dismutase/deficiency ; Superoxide Dismutase-1
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Immunolocalisation of phosphorylated STAT3, interleukin 11 and leukaemia inhibitory factor in endometrium of women with unexplained infertility during the implantation window.
    Autorzy:
    Dimitriadis E; Prince Henry's Institute of Medical Research, P,O, Box 5152, Clayton, VIC, 3168, Australia. />Sharkey AM
    Tan YL
    Salamonsen LA
    Sherwin JR
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    Źródło:
    Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2007 Nov 29; Vol. 5, pp. 44. Date of Electronic Publication: 2007 Nov 29.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Embryo Implantation*
    Endometrium/*metabolism
    Infertility, Female/*metabolism
    Interleukin-11/*metabolism
    Leukemia Inhibitory Factor/*metabolism
    STAT3 Transcription Factor/*metabolism
    Adult ; Epithelium/metabolism ; Female ; Fertility ; Humans ; Immunohistochemistry/methods ; Infertility, Female/etiology ; Receptors, Interleukin-11/metabolism ; Staining and Labeling ; Stromal Cells/metabolism ; Time Factors ; Tissue Distribution
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Aberrant regulation of interleukin-12 receptor beta2 chain on type 1 cytokine-stimulated T lymphocytes in type 1 diabetes.
    Autorzy:
    Skarsvik S; Division of Pediatrics, Department of Molecular and Clinical Medicine, Clinical Research Centre, Linköping University, Linköping, Sweden. />Ludvigsson J
    Vaarala O
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    Źródło:
    Immunology [Immunology] 2005 Feb; Vol. 114 (2), pp. 287-93.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cytokines/*immunology
    Diabetes Mellitus, Type 1/*immunology
    Receptors, Interleukin/*immunology
    T-Lymphocytes/*immunology
    CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Case-Control Studies ; Cell Polarity ; Cells, Cultured ; Child ; Flow Cytometry ; Humans ; Interleukin-11 Receptor alpha Subunit ; Lymphocyte Activation ; Mitogens/pharmacology ; Receptors, Interleukin-11 ; Statistics, Nonparametric ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Uterine extracellular matrix components are altered during defective decidualization in interleukin-11 receptor alpha deficient mice.
    Autorzy:
    White CA; Prince Henry's Institute of Medical Research, Clayton, Victoria 3168, Australia. />Robb L
    Salamonsen LA
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    Źródło:
    Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2004 Nov 10; Vol. 2, pp. 76. Date of Electronic Publication: 2004 Nov 10.
    Typ publikacji:
    Journal Article; Validation Study
    MeSH Terms:
    Extracellular Matrix/*genetics
    Receptors, Interleukin/*deficiency
    Uterus/*cytology
    Animals ; Computer Systems ; Crosses, Genetic ; DNA, Complementary/genetics ; Decidua/chemistry ; Decidua/metabolism ; Decidua/surgery ; Embryo Implantation/genetics ; Female ; Gene Expression Profiling/methods ; Gene Expression Regulation, Developmental/genetics ; Genes/genetics ; Genes/immunology ; Immunohistochemistry/methods ; Interleukin-11 Receptor alpha Subunit ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Microarray Analysis/methods ; Organ Size/genetics ; Pregnancy ; Pregnancy, Animal ; Receptors, Interleukin/physiology ; Receptors, Interleukin-11 ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Uterus/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Expression of interleukin-11 receptor in CD38-positive cells from patients with multiple myeloma.
    Autorzy:
    Tsimanis A; Department of Molecular Cell Biology, Zetiq Technologies, Rehovot Business Park, Gad Feinstein Road, Rehovot, Israel.
    Shtalrid M
    Shvidel L
    Kalinkovich A
    Berrebi A
    Klepfish A
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    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2004 Nov; Vol. 45 (11), pp. 2315-9.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    ADP-ribosyl Cyclase/*biosynthesis
    Antigens, CD/*biosynthesis
    Bone Marrow Cells/*metabolism
    Leukocytes, Mononuclear/*metabolism
    Multiple Myeloma/*metabolism
    Receptors, Interleukin/*biosynthesis
    ADP-ribosyl Cyclase 1 ; Adult ; Aged ; Aged, 80 and over ; Cell Proliferation ; Female ; Flow Cytometry ; Humans ; Interleukin-11 Receptor alpha Subunit ; Male ; Membrane Glycoproteins ; Middle Aged ; Plasma Cells/metabolism ; RNA, Messenger/metabolism ; Receptors, Interleukin-11 ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    IL-11 and IL-11Ralpha immunolocalisation at primate implantation sites supports a role for IL-11 in placentation and fetal development.
    Autorzy:
    Dimitriadis E; Prince Henry's Institute of Medical Research, PO Box 5152, Clayton, Victoria 3168, Australia. />Robb L
    Liu YX
    Enders AC
    Martin H
    Stoikos C
    Wallace E
    Salamonsen LA
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    Źródło:
    Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2003 Apr 11; Vol. 1, pp. 34. Date of Electronic Publication: 2003 Apr 11.
    Typ publikacji:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Embryo Implantation/*physiology
    Embryonic and Fetal Development/*physiology
    Interleukin-11/*physiology
    Placentation/*physiology
    Receptors, Interleukin/*physiology
    Animals ; Chorionic Villi/chemistry ; Decidua/chemistry ; Endometrium/chemistry ; Estrous Cycle/physiology ; Female ; Humans ; Interleukin-11/analysis ; Interleukin-11 Receptor alpha Subunit ; Macaca fascicularis ; Macaca mulatta ; Pregnancy ; Pregnancy Trimester, First ; Receptors, Interleukin/analysis ; Receptors, Interleukin-11 ; Species Specificity ; Trophoblasts/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Over-expression of the functional interleukin-11 alpha receptor in the development of B-cell chronic lymphocytic leukemia.
    Autorzy:
    Tsimanis A; Department of Hematology, Kaplan Medical Center, POB 1, Rehovot, 76100, Israel. />Shvidel L
    Klepfish A
    Shtalrid M
    Kalinkovich A
    Berrebi A
    Pokaż więcej
    Źródło:
    Leukemia & lymphoma [Leuk Lymphoma] 2001 Jun; Vol. 42 (1-2), pp. 195-205.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Leukemia, Lymphocytic, Chronic, B-Cell/*blood
    Receptors, Interleukin/*genetics
    Aged ; Aged, 80 and over ; Apoptosis/drug effects ; B-Lymphocytes/drug effects ; B-Lymphocytes/metabolism ; B-Lymphocytes/pathology ; Case-Control Studies ; Cell Culture Techniques ; Humans ; Interleukin-11/genetics ; Interleukin-11/pharmacology ; Interleukin-11 Receptor alpha Subunit ; Leukemia, Lymphocytic, Chronic, B-Cell/etiology ; Lymphocyte Activation/drug effects ; Middle Aged ; RNA, Messenger/analysis ; RNA, Messenger/metabolism ; Receptors, Interleukin-11 ; Recombinant Proteins/pharmacology ; Reverse Transcriptase Polymerase Chain Reaction
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Hematopoietic, immunomodulatory and epithelial effects of interleukin-11.
    Autorzy:
    Schwertschlag US; Genetics Institute, Cambridge, MA 02140, USA.
    Trepicchio WL
    Dykstra KH
    Keith JC
    Turner KJ
    Dorner AJ
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    Źródło:
    Leukemia [Leukemia] 1999 Sep; Vol. 13 (9), pp. 1307-15.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Adjuvants, Immunologic/*pharmacology
    Hematopoiesis/*drug effects
    Interleukin-11/*pharmacology
    Acute-Phase Reaction ; Animals ; Epithelium/drug effects ; Gene Expression ; Humans ; Interleukin-11/genetics ; Interleukin-11 Receptor alpha Subunit ; Receptors, Interleukin/genetics ; Receptors, Interleukin-11 ; Recombinant Proteins/pharmacology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Interleukin-11 (IL-11) enhances clonal proliferation of acute myelogenous leukemia cells with strong expression of the IL-11 receptor alpha chain and signal transducing gp130.
    Autorzy:
    Kimura T; Department of Hygiene, Kyoto Prefectural University of Medicine, Kyoto, Japan.
    Sakabe H
    Minamiguchi H
    Fujiki H
    Abe T
    Kaneko H
    Yokota S
    Nakagawa H
    Fujii H
    Tamaki H
    Ogawa H
    Sugiyama H
    Sonoda Y
    Pokaż więcej
    Źródło:
    Leukemia [Leukemia] 1999 Jul; Vol. 13 (7), pp. 1018-27.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antigens, CD/*analysis
    Interleukin-11/*therapeutic use
    Leukemia, Myeloid/*drug therapy
    Membrane Glycoproteins/*analysis
    Peptide Fragments/*analysis
    Receptors, Interleukin/*chemistry
    Signal Transduction/*drug effects
    Acute Disease ; Adolescent ; Adult ; Aged ; Cell Division/drug effects ; Cytokine Receptor gp130 ; Female ; Flow Cytometry ; Humans ; Interleukin-11 Receptor alpha Subunit ; Leukemia, Myeloid/pathology ; Male ; Middle Aged ; Receptors, Interleukin-11 ; Tumor Cells, Cultured ; Tumor Stem Cell Assay
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
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