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Wyszukujesz frazę ""Receptors, Interleukin-12"" wg kryterium: Temat


Tytuł :
Interleukin 35 Delays Hindlimb Ischemia-Induced Angiogenesis Through Regulating ROS-Extracellular Matrix but Spares Later Regenerative Angiogenesis.
Autorzy :
Fu H; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Sun Y; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Shao Y; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Saredy J; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Cueto R; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Liu L; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Drummer C 4th; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Johnson C; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Xu K; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Lu Y; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Li X; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Meng S; Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX, United States.
Xue ER; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Tan J; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Jhala NC; Department of Pathology & Laboratory Medicine Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Yu D; Department of Clinical Sciences, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Zhou Y; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center, Temple Health, Philadelphia, PA, United States.
Bayless KJ; Department of Molecular and Cellular Medicine, Texas A&M University College of Medicine, College Station, TX, United States.
Yu J; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Rogers TJ; Center for Inflammation, Translational and Clinical Lung Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Hu W; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Snyder NW; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Sun J; Center for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA, United States.
Qin X; National Primate Research Center, Tulane University, Covington, LA, United States.
Jiang X; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.; Center for Inflammation, Translational and Clinical Lung Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Wang H; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
Yang X; Cardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.; Centers for Metabolic Disease Research, Cardiovascular Research, Thrombosis Research, Departments of Pharmacology, Microbiology and Immunology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.; Center for Inflammation, Translational and Clinical Lung Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, United States.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Oct 14; Vol. 11, pp. 595813. Date of Electronic Publication: 2020 Oct 14 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hindlimb/*blood supply
Interleukins/*immunology
Ischemia/*immunology
Receptors, Interleukin-12/*immunology
Animals ; Apolipoproteins E/genetics ; Cell Line ; Cell Movement ; Extracellular Matrix/immunology ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Neovascularization, Pathologic ; Neovascularization, Physiologic ; Reactive Oxygen Species/immunology ; Receptors, Interleukin-12/genetics
Czasopismo naukowe
Tytuł :
IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE.
Autorzy :
Mondal S; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612.
Kundu M; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.
Jana M; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612.
Roy A; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612.
Rangasamy SB; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612.
Modi KK; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612.
Wallace J; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612.
Albalawi YA; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL 60612.
Balabanov R; Department of Neurology, Northwestern University, Chicago, IL 60611.
Pahan K; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612; .; Division of Research and Development, Jesse Brown Veterans Affairs Medical Center, Chicago, IL 60612.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Sep 01; Vol. 117 (35), pp. 21557-21567. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Encephalomyelitis, Autoimmune, Experimental/*immunology
Interleukin-12 Subunit p40/*immunology
Interleukin-12 Subunit p40/*pharmacology
Receptors, Interleukin-12/*antagonists & inhibitors
Adult ; Animals ; Cells, Cultured ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/drug therapy ; Female ; Humans ; Interleukin-12/immunology ; Interleukin-12/metabolism ; Interleukin-23/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Multiple Sclerosis/blood ; Multiple Sclerosis/immunology ; Protein Binding ; Receptors, Interleukin-12/immunology ; Recombinant Proteins/pharmacology ; Signal Transduction ; Th17 Cells/drug effects ; Th17 Cells/immunology
Czasopismo naukowe
Tytuł :
Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors.
Autorzy :
Esch A; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Masiarz A; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Mossner S; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Moll JM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Grötzinger J; Institute of Biochemistry, Medical Faculty, Christian Albrechts University, Kiel, Germany.
Schröder J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Scheller J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Floss DM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2020 Jul 24; Vol. 295 (30), pp. 10478-10492. Date of Electronic Publication: 2020 Jun 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Interleukin-12 Subunit p40*/chemistry
Interleukin-12 Subunit p40*/genetics
Interleukin-12 Subunit p40*/metabolism
Interleukin-23 Subunit p19*/chemistry
Interleukin-23 Subunit p19*/genetics
Interleukin-23 Subunit p19*/metabolism
Receptors, Interleukin*/chemistry
Receptors, Interleukin*/genetics
Receptors, Interleukin*/metabolism
Receptors, Interleukin-12*/chemistry
Receptors, Interleukin-12*/genetics
Receptors, Interleukin-12*/metabolism
Amino Acid Substitution ; Animals ; CHO Cells ; COS Cells ; Chlorocebus aethiops ; Cricetulus ; HEK293 Cells ; Humans ; Mice ; Mutation, Missense ; Protein Binding
Czasopismo naukowe
Tytuł :
Autocrine TGF-β1 Maintains the Stability of Foxp3 Regulatory T Cells via IL-12Rβ2 Downregulation.
Autorzy :
Choi G; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Na H; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Kuen DS; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
Kim BS; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.; Division of Life Sciences, College of Life Science and Bioengineering, Incheon National University, Incheon 22012, Korea.
Chung Y; Laboratory of Immune Regulation, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Korea.; BK21 Plus Program, College of Pharmacy, Seoul National University, Seoul 08826, Korea.
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Źródło :
Biomolecules [Biomolecules] 2020 May 27; Vol. 10 (6). Date of Electronic Publication: 2020 May 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Down-Regulation*
Forkhead Transcription Factors/*metabolism
Receptors, Interleukin-12/*metabolism
T-Lymphocytes, Regulatory/*metabolism
Transforming Growth Factor beta1/*metabolism
Animals ; Autocrine Communication ; Forkhead Transcription Factors/genetics ; Mice ; Mice, Inbred Strains ; Mice, Knockout ; Mice, Transgenic ; Receptors, Interleukin-12/genetics
Czasopismo naukowe
Tytuł :
Novel nonsense IL-12Rβ1 mutation associated with recurrent tuberculosis.
Autorzy :
Ul Akbar N; Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan.
Khan SN; Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan.
Amin MU; Department of Pharmacy, Abasyn University, Peshawar, KPK, Pakistan.
Ishfaq M; Centre for Omic Sciences, Islamia College University, Peshawar, Pakistan.
Cabral-Marques O; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Schimke LF; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg im Breisgau, Germany.
Iqbal A; Department of Pharmacology, University of Illinois at Chicago, Chicago, IL, USA.
Ullah I; Suliman Bin Aba-Alkhail Center for Interdisciplinary Research in Basic Sciences (SA-CIRBS), International Islamic University, Islamabad, Pakistan.
Hussain M; Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan.
Ali I; Department of Biosciences, COMSATS University Islamabad, Islamabad, Pakistan.
Khan N; Interdisciplinary Nanoscience Center, Aarhus University, Gustav Wieds Vej 14, 8000, Aarhus, Denmark.
El Khawanky N; Department of Hematology, Oncology and Stem Cell Transplantation, Freiburg University Medical Center, Freiburg, Germany.; Precision Medicine Theme, The South Australian Health and Medical Research Institute (SAHMRI), Adelaide, Australia.
Rahman H; Department of Microbiology, Faculty of Health Sciences, Abdul Wali Khan University Mardan (AWKUM), Mardan, KPK, Pakistan.
Khan TA; Department of Microbiology, Kohat University of Science and Technology, Kohat, Pakistan. .
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Źródło :
Immunologic research [Immunol Res] 2019 Oct; Vol. 67 (4-5), pp. 408-415.
Typ publikacji :
Case Reports; Clinical Trial; Journal Article
MeSH Terms :
Codon, Nonsense*
Receptors, Interleukin-12*/genetics
Receptors, Interleukin-12*/immunology
Tuberculosis*/genetics
Tuberculosis*/immunology
Tuberculosis*/pathology
Adult ; Child ; Exons ; Female ; Humans ; Phosphorylation ; Recurrence ; STAT4 Transcription Factor/genetics ; STAT4 Transcription Factor/immunology ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology
Czasopismo naukowe
Tytuł :
Associations of IL-12, IL12R polymorphisms and serum IL-12 levels with high-risk human papillomavirus susceptibility in rural women from Luohe, Henan, China.
Autorzy :
Song J; Department of Pharmacology, Luohe Medical College.
Zhang Q; Department of Obstetrics and Gynecology, Luohe Central Hospital, Luohe, Henan.
Wang R; Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia.
Sun M; Department of Pharmacology, Luohe Medical College.
Jin S; Department of Pharmacology, Luohe Medical College.; Tumor Occurrence and Prevention Research Innovation Team of Henan, Luohe, Henan, China.
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Źródło :
Medicine [Medicine (Baltimore)] 2019 Sep; Vol. 98 (38), pp. e16991.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Predisposition to Disease*
Interleukin-12 Subunit p40/*genetics
Papillomavirus Infections/*genetics
Receptors, Interleukin-12/*genetics
Adult ; Aged ; Asian Continental Ancestry Group ; Case-Control Studies ; China ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Interleukin-12 Subunit p40/blood ; Middle Aged ; Polymorphism, Single Nucleotide ; Receptors, Interleukin-12/blood ; Rural Population
Czasopismo naukowe
Tytuł :
Mendelian susceptibility to mycobacterial disease: Clinical and immunological findings of patients suspected for IL12Rβ1 deficiency.
Autorzy :
Moradi L; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Cheraghi T; Department of Pediatrics, 17th Shahrivar Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Yazdani R; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Azizi G; Non-communicable Diseases Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Rasouli S; Department of Medical Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Zavareh FT; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Parvaneh L; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Parvaneh N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Sohani M; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Delavari S; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Abolhassani H; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran; Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institute at Karolinska University Hospital Huddinge, Stockholm, Sweden.
Rezaei N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Aghamohammadi A; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: .
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Źródło :
Allergologia et immunopathologia [Allergol Immunopathol (Madr)] 2019 Sep - Oct; Vol. 47 (5), pp. 491-498. Date of Electronic Publication: 2019 Jul 23.
Typ publikacji :
Journal Article
MeSH Terms :
Herpes Simplex/*immunology
Immunologic Deficiency Syndromes/*immunology
Mutation/*genetics
Mycobacterium Infections, Nontuberculous/*immunology
Mycobacterium bovis/*immunology
Receptors, Interleukin-12/*genetics
Simplexvirus/*physiology
Adolescent ; Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Herpes Simplex/genetics ; Humans ; Immunologic Deficiency Syndromes/genetics ; Infant ; Male ; Mycobacterium Infections, Nontuberculous/genetics ; Prospective Studies ; Receptors, Interleukin-12/metabolism
Czasopismo naukowe
Tytuł :
Interleukin-12 receptor β2 from grass carp: Molecular characterization and its involvement in Aeromonas hydrophila-induced intestinal inflammation.
Autorzy :
Song XH; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Tang J; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Gao TT; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Xu XF; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Yang HX; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Wu K; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Yang CG; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Cheng ZQ; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China.
Sun BY; School of Biology and Basic Medical Sciences, Soochow University, 199 Ren'ai Road, Suzhou, Jiangsu, 215123, China. Electronic address: .
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2019 Apr; Vol. 87, pp. 226-234. Date of Electronic Publication: 2019 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
Adaptive Immunity/*genetics
Carps/*genetics
Carps/*immunology
Fish Diseases/*immunology
Gene Expression Regulation/*immunology
Receptors, Interleukin-12/*genetics
Receptors, Interleukin-12/*immunology
Aeromonas hydrophila/physiology ; Amino Acid Sequence ; Animals ; Base Sequence ; Fish Proteins/chemistry ; Fish Proteins/genetics ; Fish Proteins/immunology ; Gene Expression Profiling/veterinary ; Gram-Negative Bacterial Infections/immunology ; Receptors, Interleukin-12/chemistry ; Sequence Alignment/veterinary
Czasopismo naukowe
Tytuł :
Three novel compound heterozygous IL12RB1 mutations in Chinese patients with Mendelian susceptibility to mycobacterial disease.
Autorzy :
Zhou X; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Jia W; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Ni Z; Wuhan Jinyintan Hospital, Wuhan, Hubei, China.
Wang A; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Liu Z; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Hou M; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhou M; Wuhan Jinyintan Hospital, Wuhan, Hubei, China.
Tang Z; Wuhan Jinyintan Hospital, Wuhan, Hubei, China.
Zhang D; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Li L; Wuhan Jinyintan Hospital, Wuhan, Hubei, China.
Han T; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Tan Y; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Luo G; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wang J; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Wu Y; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Zhang X; Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Science and Technology and Center for Human Genome Research, Huazhong University of Science and Technology, Wuhan, Hubei, China.
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Źródło :
PloS one [PLoS One] 2019 Apr 18; Vol. 14 (4), pp. e0215648. Date of Electronic Publication: 2019 Apr 18 (Print Publication: 2019).
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Heterozygote*
Point Mutation*
Mycobacterium Infections/*genetics
Receptors, Interleukin-12/*genetics
Asian Continental Ancestry Group ; China ; Female ; Humans ; Infant ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Male ; Mycobacterium Infections/immunology ; Receptors, Interleukin-12/immunology
Czasopismo naukowe
Tytuł :
Characterization of two novel mutations in IL-12R signaling in MSMD patients.
Autorzy :
Fayez EA; Department of Immunology, School of Medicine, Iran University of Medical Sciences Tehran, Iran.
Koohini Z; Department of Medical Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Koohini Z; Department of Immunology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Zamanzadeh H; Department of biology, School of basic sciences, University of Sistan and Balouchestan, Zahedan, Iran.
de Boer M; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Roos D; Sanquin Research, and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Teimourian S; Department of Medical Genetics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
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Źródło :
Pathogens and disease [Pathog Dis] 2019 Apr 01; Vol. 77 (3).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Leukocytes, Mononuclear/*immunology
Mycobacterium bovis/*immunology
Receptors, Interleukin-12/*genetics
Tuberculosis/*genetics
Female ; Flow Cytometry ; Humans ; Infant ; Interleukin-12 Subunit p35/genetics ; Interleukin-12 Subunit p40/genetics ; Male ; Receptors, Interferon/genetics ; Receptors, Interleukin-12/analysis ; Signal Transduction
Czasopismo naukowe
Tytuł :
Human IL12RB1 expression is allele-biased and produces a novel IL12 response regulator.
Autorzy :
Reeme AE; Department of Microbiology and Immunology, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Claeys TA; Department of Microbiology and Immunology, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Aggarwal P; Department of Pediatrics, Section of Genomic Pediatrics and Children's Research Institute, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Turner AJ; Department of Pediatrics, Section of Genomic Pediatrics and Children's Research Institute, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Routes JM; Department of Pediatrics, Section of Asthma, Allergy and Clinical Immunology, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Broeckel U; Department of Pediatrics, Section of Genomic Pediatrics and Children's Research Institute, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
Robinson RT; Department of Microbiology and Immunology, The Medical College of Wisconsin, Milwaukee, WI, 53226, USA. .
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Źródło :
Genes and immunity [Genes Immun] 2019 Mar; Vol. 20 (3), pp. 181-197. Date of Electronic Publication: 2018 Mar 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Alleles*
RNA Splicing*
Interleukin-12/*genetics
Receptors, Interleukin-12/*genetics
Cells, Cultured ; Heterogeneous-Nuclear Ribonucleoprotein Group F-H/metabolism ; Humans ; Interleukin-12/metabolism ; Jurkat Cells ; Lung/metabolism ; Protein Binding ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Receptors, Interleukin-12/metabolism ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Production of IL-17A at Innate Immune Phase Leads to Decreased Th1 Immune Response and Attenuated Host Defense against Infection with Cryptococcus deneoformans .
Autorzy :
Sato K; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan; .
Yamamoto H; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Nomura T; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kasamatsu J; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Miyasaka T; Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Sendai, Miyagi 981-0905, Japan.
Tanno D; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Matsumoto I; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kagesawa T; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Miyahara A; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Zong T; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Oniyama A; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kawamura K; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Yokoyama R; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kitai Y; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Ishizuka S; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kanno E; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Tanno H; Department of Science of Nursing Practice, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Suda H; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan; and.
Morita M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan; and.
Yamamoto M; Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan; and.
Iwakura Y; Research Institute for Biological Sciences, Tokyo University of Science, Noda, Chiba 278-0022, Japan.
Ishii K; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
Kawakami K; Department of Intelligent Network for Infection Control, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.; Department of Medical Microbiology, Mycology and Immunology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan.
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Aug 01; Vol. 205 (3), pp. 686-698. Date of Electronic Publication: 2020 Jun 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Innate*
Cryptococcosis/*immunology
Cryptococcus/*immunology
Dendritic Cells/*immunology
Interleukin-17/*immunology
Th1 Cells/*immunology
Animals ; Cryptococcosis/genetics ; Cryptococcus/genetics ; Interferon-gamma/genetics ; Interferon-gamma/immunology ; Interleukin-17/genetics ; Killer Cells, Natural/immunology ; Mice ; Mice, Knockout ; Natural Killer T-Cells/immunology ; Receptors, Antigen, T-Cell, gamma-delta/genetics ; Receptors, Antigen, T-Cell, gamma-delta/immunology ; Receptors, Interleukin-12/genetics ; Receptors, Interleukin-12/immunology
Czasopismo naukowe
Tytuł :
Interferon-γ-dependent protection against Neospora caninum infection conferred by mucosal immunization in IL-12/IL-23 p40-deficient mice.
Autorzy :
Ferreirinha P; I3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; IBMC - Instituto de Biologia Molecular e Celular, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Fróis-Martins R; I3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; IBMC - Instituto de Biologia Molecular e Celular, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.
Teixeira L; ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; UMIB - Unidade Multidisciplinar de Investigação Biomédica, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Rocha A; ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; CECA/ICETA - Centro de Estudos de Ciência Animal, Universidade do Porto, Praça Gomes Teixeira, Apartado 55142, 4051-401 Porto, Portugal.
Vilanova M; I3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; IBMC - Instituto de Biologia Molecular e Celular, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; ICBAS - Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Correia A; I3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; IBMC - Instituto de Biologia Molecular e Celular, Rua Alfredo Allen, 208, 4200-135 Porto, Portugal; DGAOT, Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre, 4169-007 Porto, Portugal. Electronic address: .
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Źródło :
Vaccine [Vaccine] 2018 Aug 06; Vol. 36 (32 Pt B), pp. 4890-4896. Date of Electronic Publication: 2018 Jul 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Protozoan/*immunology
Interferon-gamma/*metabolism
Interleukin-12/*metabolism
Interleukin-23/*metabolism
Neospora/*immunology
Receptors, Interleukin-12/*deficiency
Animals ; Antibodies, Protozoan/immunology ; Female ; Immunity, Mucosal/immunology ; Immunization ; Interferon-gamma/genetics ; Interleukin-12/genetics ; Interleukin-23/genetics ; Mice ; Mice, Inbred C57BL ; Real-Time Polymerase Chain Reaction ; Receptors, Interleukin-12/genetics
Czasopismo naukowe
Tytuł :
Disseminated Coccidioidomycosis Treated with Interferon-γ and Dupilumab.
Autorzy :
Tsai M; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Thauland TJ; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Huang AY; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Bun C; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Fitzwater S; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Krogstad P; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Douine ED; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Nelson SF; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Lee H; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Garcia-Lloret MI; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
Butte MJ; From the Divisions of Immunology, Allergy, and Rheumatology (M.T., T.J.T., C.B., M.I.G.-L., M.J.B.) and Infectious Diseases (S.F., P.K.), Department of Pediatrics, the Department of Human Genetics (E.D.D., S.F.N., H.L.), the Department of Pathology and Laboratory Medicine (H.L.), and the California Center for Rare Diseases, Institute for Precision Health (A.Y.H., S.F.N., M.J.B.), University of California, Los Angeles, Los Angeles.
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Źródło :
The New England journal of medicine [N Engl J Med] 2020 Jun 11; Vol. 382 (24), pp. 2337-2343.
Typ publikacji :
Case Reports; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Humanized/*therapeutic use
Antifungal Agents/*therapeutic use
Coccidioidomycosis/*drug therapy
Interferon-gamma/*therapeutic use
Brain/diagnostic imaging ; Child, Preschool ; Coccidioidomycosis/immunology ; Disease Progression ; Drug Therapy, Combination ; Humans ; Interferon-gamma/metabolism ; Interleukin-12/metabolism ; Interleukin-13/antagonists & inhibitors ; Interleukin-4/antagonists & inhibitors ; Interleukin-4/metabolism ; Magnetic Resonance Imaging ; Male ; Protein Isoforms ; Receptors, Interleukin-12/chemistry ; Receptors, Interleukin-12/genetics ; Spine/diagnostic imaging ; Th1 Cells/immunology
Czasopismo naukowe
Tytuł :
The monogenic basis of human tuberculosis.
Autorzy :
Boisson-Dupuis S; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM UMR1163, Paris, France. .; Paris Descartes University, Imagine Institute, Paris, France. .; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, New York, USA. .
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Źródło :
Human genetics [Hum Genet] 2020 Jun; Vol. 139 (6-7), pp. 1001-1009. Date of Electronic Publication: 2020 Feb 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Genetic Heterogeneity*
Genetic Predisposition to Disease*
Genetic Diseases, Inborn/*genetics
Interferon-gamma/*immunology
Mycobacterium tuberculosis/*genetics
Mycobacterium tuberculosis/*immunology
Tuberculosis/*genetics
Genetic Diseases, Inborn/immunology ; Genetic Diseases, Inborn/microbiology ; Homozygote ; Humans ; Receptors, Interleukin-12/genetics ; Receptors, Interleukin-12/immunology ; TYK2 Kinase/genetics ; TYK2 Kinase/immunology ; Tuberculosis/immunology ; Tuberculosis/microbiology ; Tuberculosis/pathology
Czasopismo naukowe
Tytuł :
Susceptibility to mycobacterial disease due to mutations in IL-12Rβ1 in three Iranian patients.
Autorzy :
Alinejad Dizaj M; Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mortaz E; Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. .; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands. .
Mahdaviani SA; Pediatric Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mansouri D; Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mehrian P; Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Verhard EM; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Varahram M; Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Babaie D; Department of Allergy and Clinical Immunology, Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Adcock IM; Cell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, Dovehouse Street, London, UK.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute, The University of Newcastle, Newcastle, New South Wales, Australia.
Garssen J; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.; Nutricia Research Centre for Specialized Nutrition, Utrecht, The Netherlands.
van de Vosse E; Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Velayati A; Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
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Źródło :
Immunogenetics [Immunogenetics] 2018 Jun; Vol. 70 (6), pp. 373-379. Date of Electronic Publication: 2017 Dec 18.
Typ publikacji :
Case Reports; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Mycobacterium Infections/*genetics
Receptors, Interleukin-12/*genetics
Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Humans ; Iran ; Male ; Mycobacterium/isolation & purification ; Mycobacterium Infections/immunology ; Mycobacterium tuberculosis/isolation & purification ; Pedigree ; Receptors, Interleukin-12/immunology ; Tuberculosis/genetics ; Tuberculosis/microbiology
Czasopismo naukowe
Tytuł :
Morphological and Functional Characterization of IL-12Rβ2 Chain on Intestinal Epithelial Cells: Implications for Local and Systemic Immunoregulation.
Autorzy :
Regoli M; Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Man A; Gut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Gicheva N; Gut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Dumont A; European Food Safety Authority, EFSA, Parma, Italy.
Ivory K; Gut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Pacini A; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Morucci G; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Branca JJV; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Lucattelli M; Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Santosuosso U; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Narbad A; Gut Health Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Gulisano M; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Bertelli E; Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Nicoletti C; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
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Źródło :
Frontiers in immunology [Front Immunol] 2018 May 29; Vol. 9, pp. 1177. Date of Electronic Publication: 2018 May 29 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunity, Mucosal*
Models, Immunological*
Epithelial Cells/*immunology
Food Hypersensitivity/*immunology
Intestinal Mucosa/*immunology
Receptors, Interleukin-12/*immunology
Animals ; Coculture Techniques ; Epithelial Cells/pathology ; Food Hypersensitivity/pathology ; Interleukin-12/immunology ; Intestinal Mucosa/pathology ; Lactococcus lactis/immunology ; Mice ; Mice, Knockout ; Receptors, Interleukin-12/genetics
Czasopismo naukowe
Tytuł :
Mendelian susceptibility to mycobacterial disease-Challenges in hematopoietic stem cell transplantation.
Autorzy :
Patel S; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
Uppuluri R; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
Vellaichamy Swaminathan V; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
Ravichandran N; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
Melarcode Ramanan K; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
Raj R; Department of Pediatric Hematology, Oncology, Blood and Marrow Transplantation, Apollo Hospitals, Anna Salai, Teynampet, Chennai, Tamil Nadu, India.
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Źródło :
Pediatric blood & cancer [Pediatr Blood Cancer] 2020 May; Vol. 67 (5), pp. e28187. Date of Electronic Publication: 2020 Jan 21.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Hematopoietic Stem Cell Transplantation*
Immunosuppression*
Mycobacterium*
Mycobacterium Infections*/genetics
Mycobacterium Infections*/therapy
Transplantation Conditioning*
Dexamethasone/*administration & dosage
Receptors, Interleukin-12/*genetics
Vidarabine/*analogs & derivatives
Allografts ; Child, Preschool ; Genetic Predisposition to Disease ; Humans ; Infant ; Male ; Mutation ; Vidarabine/administration & dosage
Czasopismo naukowe
Tytuł :
Coexistence of 2 rare autosomal recessively inherited disorders manifesting with immune deficiency; IL-12 receptor β1 and biotinidase deficiencies.
Autorzy :
Doğruel D; Division of Allergy and Immunology, Çukurova University Faculty of Medicine, Adana, Turkey.
Bulut FD; Metabolism and Nutrition, Department of Pediatrics, Çukurova University Faculty of Medicine, Adana, Turkey.
Yılmaz M; Division of Allergy and Immunology, Çukurova University Faculty of Medicine, Adana, Turkey.
Önenli-Mungan N; Metabolism and Nutrition, Department of Pediatrics, Çukurova University Faculty of Medicine, Adana, Turkey.
Altıntaş DU; Division of Allergy and Immunology, Çukurova University Faculty of Medicine, Adana, Turkey.
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Źródło :
The Turkish journal of pediatrics [Turk J Pediatr] 2018; Vol. 60 (5), pp. 584-587.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Biotinidase Deficiency/*complications
Immunologic Deficiency Syndromes/*diagnosis
Receptors, Interleukin-12/*deficiency
Antitubercular Agents/therapeutic use ; Biotinidase Deficiency/genetics ; DNA Mutational Analysis/methods ; Female ; Humans ; Immunologic Deficiency Syndromes/genetics ; Infant ; Infant, Newborn ; Interferon-gamma/therapeutic use ; Mutation ; Neonatal Screening/methods ; Receptors, Interleukin-12/genetics
Czasopismo naukowe
Tytuł :
IL-6/IL-12 Cytokine Receptor Shuffling of Extra- and Intracellular Domains Reveals Canonical STAT Activation via Synthetic IL-35 and IL-39 Signaling.
Autorzy :
Floss DM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany. .
Schönberg M; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Franke M; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Horstmeier FC; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Engelowski E; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Schneider A; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Rosenfeldt EM; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany.
Scheller J; Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, 40225, Düsseldorf, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2017 Nov 09; Vol. 7 (1), pp. 15172. Date of Electronic Publication: 2017 Nov 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Signal Transduction*
Interleukins/*metabolism
Receptors, Interleukin-12/*metabolism
Receptors, Interleukin-6/*metabolism
Recombinant Proteins/*metabolism
STAT Transcription Factors/*metabolism
Animals ; Cell Line ; Interleukins/genetics ; Mice ; Protein Binding ; Receptors, Interleukin-12/genetics ; Receptors, Interleukin-6/genetics ; Recombinant Proteins/genetics
Czasopismo naukowe

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