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Wyszukujesz frazę ""Receptors, Interleukin-12"" wg kryterium: Temat

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    Wyświetlanie 1-18 z 18
    Tytuł:
    Massive interleukin-12-induced interferon-gamma production by interleukin-15-stimulated lamina propria lymphocytes followed by down-regulation of the interleukin-12 receptor.
    Autorzy:
    Ebert EC; UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA. />Jabri B
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    Źródło:
    Immunology [Immunology] 2008 Aug; Vol. 124 (4), pp. 453-60. Date of Electronic Publication: 2008 Jun 28.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Interferon-gamma/*biosynthesis
    Interleukin-12/*immunology
    Interleukin-15/*immunology
    Intestinal Mucosa/*immunology
    Receptors, Interleukin-12/*immunology
    CD4-Positive T-Lymphocytes/immunology ; Cell Proliferation ; Cells, Cultured ; Cytokines/biosynthesis ; Down-Regulation/immunology ; Humans ; Immunity, Mucosal ; Jejunum/immunology ; Mucous Membrane ; Phosphorylation ; Receptors, Interleukin-12/metabolism ; STAT Transcription Factors/metabolism ; Up-Regulation/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis.
    Autorzy:
    Jana M; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
    Mondal S
    Jana A
    Pahan K
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    Źródło:
    Immunology [Immunology] 2014 Apr; Vol. 141 (4), pp. 549-63.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Encephalomyelitis, Autoimmune, Experimental/*metabolism
    Interleukin-12/*metabolism
    Interleukin-23/*metabolism
    Interleukin-7/*metabolism
    Macrophages, Peritoneal/*metabolism
    Microglia/*metabolism
    Multiple Sclerosis/*metabolism
    Animals ; Astrocytes/immunology ; Astrocytes/metabolism ; Cells, Cultured ; Encephalomyelitis, Autoimmune, Experimental/genetics ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Genes, Reporter ; HIV Envelope Protein gp120/immunology ; HIV Envelope Protein gp120/metabolism ; Humans ; Interleukin-12/genetics ; Interleukin-12/immunology ; Interleukin-12 Subunit p35/immunology ; Interleukin-12 Subunit p35/metabolism ; Interleukin-12 Subunit p40/immunology ; Interleukin-12 Subunit p40/metabolism ; Interleukin-23/genetics ; Interleukin-23/immunology ; Interleukin-7/genetics ; Interleukin-7/immunology ; Lipopolysaccharides/pharmacology ; Luciferases/biosynthesis ; Luciferases/genetics ; Macrophages, Peritoneal/drug effects ; Macrophages, Peritoneal/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/drug effects ; Microglia/immunology ; Multiple Sclerosis/genetics ; Multiple Sclerosis/immunology ; Primary Cell Culture ; Promoter Regions, Genetic ; RNA, Messenger/metabolism ; Receptors, Interleukin-12/deficiency ; Receptors, Interleukin-12/genetics ; Recombinant Proteins/immunology ; Recombinant Proteins/metabolism ; Signal Transduction ; Transfection ; Up-Regulation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Interleukin-12 is sufficient to promote antigen-independent interferon-gamma production by CD8 T cells in old mice.
    Autorzy:
    Rottinghaus EK; Center for Microbial Interface Biology, The Ohio State University, Columbus, OH 43210, USA. />Vesosky B
    Turner J
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    Źródło:
    Immunology [Immunology] 2009 Sep; Vol. 128 (1 Suppl), pp. e679-90. Date of Electronic Publication: 2009 Feb 09.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Aging/*immunology
    CD8-Positive T-Lymphocytes/*immunology
    Interferon-gamma/*biosynthesis
    Interleukin-12/*physiology
    T-Lymphocyte Subsets/*immunology
    Age Factors ; Animals ; CD8-Positive T-Lymphocytes/drug effects ; Female ; Hyaluronan Receptors/drug effects ; Hyaluronan Receptors/metabolism ; Interferon-gamma/agonists ; Interleukin-12/pharmacology ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Receptors, Interleukin-12/agonists ; Receptors, Interleukin-12/metabolism ; STAT4 Transcription Factor/agonists ; STAT4 Transcription Factor/metabolism ; Signal Transduction ; T-Lymphocyte Subsets/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The secreted form of p28 subunit of interleukin (IL)-27 inhibits biological functions of IL-27 and suppresses anti-allogeneic immune responses.
    Autorzy:
    Shimozato O; Division of Pathology, Chiba Cancer Centre Research Institute, Nitona, Chiba, Japan.
    Sato A
    Kawamura K
    Chiyo M
    Ma G
    Li Q
    Tagawa M
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    Źródło:
    Immunology [Immunology] 2009 Sep; Vol. 128 (1 Suppl), pp. e816-25. Date of Electronic Publication: 2009 Mar 23.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*immunology
    Graft Survival/*immunology
    Interleukin-17/*immunology
    Neoplasms/*immunology
    T-Lymphocytes, Cytotoxic/*immunology
    Animals ; CD4-Positive T-Lymphocytes/drug effects ; COS Cells ; Cell Adhesion Molecules/agonists ; Cell Adhesion Molecules/immunology ; Cell Adhesion Molecules/metabolism ; Cell Line, Tumor ; Chlorocebus aethiops ; Female ; Interferon-gamma/biosynthesis ; Interferon-gamma/drug effects ; Interferon-gamma/immunology ; Interleukin-17/genetics ; Interleukin-17/pharmacology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Minor Histocompatibility Antigens ; Myoblasts/immunology ; Myoblasts/metabolism ; Phosphorylation ; Protein Subunits/genetics ; Protein Subunits/immunology ; Protein Subunits/pharmacology ; Receptors, Cytokine/genetics ; Receptors, Cytokine/immunology ; Receptors, Interleukin-12/agonists ; Receptors, Interleukin-12/immunology ; Receptors, Interleukin-12/metabolism ; STAT1 Transcription Factor/agonists ; STAT1 Transcription Factor/immunology ; STAT1 Transcription Factor/metabolism ; T-Lymphocytes, Cytotoxic/metabolism ; Th1 Cells/immunology ; Th1 Cells/metabolism ; Transduction, Genetic
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Human natural killer cells expressing the memory-associated marker CD45RO from tuberculous pleurisy respond more strongly and rapidly than CD45RO- natural killer cells following stimulation with interleukin-12.
    Autorzy:
    Fu X; Institute of Immunology, Zhongshan School of Medicine, Key Laboratory of Tropical Disease Control Research of Ministry of Education, Sun Yat-sen University, Guangzhou Chest Hospital of Guangzhou, Guangzhou, China.
    Liu Y
    Li L
    Li Q
    Qiao D
    Wang H
    Lao S
    Fan Y
    Wu C
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    Źródło:
    Immunology [Immunology] 2011 Sep; Vol. 134 (1), pp. 41-9. Date of Electronic Publication: 2011 Jun 29.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-12/*pharmacology
    Killer Cells, Natural/*immunology
    Killer Cells, Natural/*metabolism
    Leukocyte Common Antigens/*metabolism
    Lymphocyte Activation/*immunology
    Tuberculosis, Pleural/*immunology
    Adolescent ; Adult ; Aged ; Antigens, CD/metabolism ; Antigens, Differentiation, T-Lymphocyte/metabolism ; CD56 Antigen/metabolism ; Cell Count ; Cytotoxicity, Immunologic/drug effects ; Cytotoxicity, Immunologic/immunology ; Female ; GPI-Linked Proteins/metabolism ; Granzymes/metabolism ; Humans ; Interferon-gamma/metabolism ; Interleukin-2 Receptor alpha Subunit/metabolism ; K562 Cells/immunology ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/pathology ; Lectins, C-Type/metabolism ; Leukocytes, Mononuclear/pathology ; Lymphocyte Activation/drug effects ; Lymphocyte Subsets/drug effects ; Lymphocyte Subsets/immunology ; Lymphocyte Subsets/metabolism ; Lymphocyte Subsets/pathology ; Male ; Middle Aged ; NK Cell Lectin-Like Receptor Subfamily C/metabolism ; NK Cell Lectin-Like Receptor Subfamily K/metabolism ; Pleural Effusion/pathology ; Receptors, IgG/metabolism ; Receptors, Interleukin-12/metabolism ; Tuberculosis, Pleural/pathology ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70.
    Autorzy:
    Jana M; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL 60612, USA. malubendu_ />Pahan K
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    Źródło:
    Immunology [Immunology] 2009 Jul; Vol. 127 (3), pp. 312-25. Date of Electronic Publication: 2008 Nov 14.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-12/*immunology
    Interleukin-12 Receptor beta 1 Subunit/*immunology
    Lymphotoxin-alpha/*biosynthesis
    Animals ; Cells, Cultured ; DNA, Complementary/genetics ; Dose-Response Relationship, Immunologic ; Humans ; Inflammation Mediators/immunology ; Interleukin-12 Receptor beta 1 Subunit/genetics ; Macrophages, Peritoneal/immunology ; Mice ; Microglia/immunology ; Receptors, Interleukin-12/immunology ; Reverse Transcriptase Polymerase Chain Reaction/methods ; T-Lymphocytes/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    RNA editing of interleukin-12 receptor beta2, 2451 C-to-U (Ala 604 Val) conversion, associated with atopy.
    Autorzy:
    Kondo N; Department of Pediatrics, Gifu University School of Medicine, Tsukasa-machi 40, Gifu 500-8705, Japan. />Matsui E
    Kaneko H
    Aoki M
    Kato Z
    Fukao T
    Kasahara K
    Morimoto N
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    Źródło:
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2004 Mar; Vol. 34 (3), pp. 363-8.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gene Conversion*
    RNA Editing*
    Hypersensitivity, Immediate/*immunology
    Receptors, Interleukin/*genetics
    Case-Control Studies ; Cells, Cultured ; Chi-Square Distribution ; Child ; Down-Regulation ; Electroporation ; Flow Cytometry ; Humans ; Immunoglobulin E/immunology ; Interferon-gamma/immunology ; Interleukin-12/immunology ; RNA, Messenger/analysis ; Receptors, Interleukin-12 ; Sequence Analysis, DNA ; Signal Transduction ; Statistics, Nonparametric ; Transfection/methods
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells.
    Autorzy:
    Vecchiarelli A; Microbiology Section, Department of Experimental Medicine and Biochemical Sciences, University of Perugia, Perugia, Italy. />Pietrella D
    Bistoni F
    Kozel TR
    Casadevall A
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    Źródło:
    Immunology [Immunology] 2002 Jun; Vol. 106 (2), pp. 267-72.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Antibodies, Fungal/*immunology
    Antigen-Presenting Cells/*immunology
    Cryptococcus neoformans/*immunology
    Polysaccharides/*immunology
    Receptors, Interleukin/*metabolism
    T-Lymphocytes/*immunology
    Antigens, Fungal/immunology ; Cells, Cultured ; Humans ; Immunity, Cellular ; Phagocytosis/immunology ; Receptors, Interleukin-12
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    PHA-induced IL-12R beta(2) mRNA expression in atopic and non-atopic children.
    Autorzy:
    Janefjord CK; Department of Health and Environment, Division of Paediatrics, Clinical Research Centre, Faculty of Health Sciences, Linköping University, Linköping, Sweden. />Jenmalm MC
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    Źródło:
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2001 Oct; Vol. 31 (10), pp. 1493-500.
    Typ publikacji:
    Clinical Trial; Clinical Trial, Phase II; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hypersensitivity, Immediate/*genetics
    Phytohemagglutinins/*pharmacology
    RNA, Messenger/*drug effects
    RNA, Messenger/*physiology
    Receptors, Interleukin/*drug effects
    Receptors, Interleukin/*genetics
    Child ; Child Welfare ; Humans ; Hypersensitivity, Immediate/blood ; Interferon-gamma/biosynthesis ; Interleukin-10/metabolism ; Interleukin-13/metabolism ; Interleukin-4/metabolism ; Interleukin-5/metabolism ; RNA, Messenger/blood ; Receptors, Interleukin/blood ; Receptors, Interleukin-12 ; Skin Tests ; Sweden
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Atopy and mutations of IL-12 receptor beta 2 chain gene.
    Autorzy:
    Kondo N; Department of Paediatrics, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu 500-8705, Japan. />Matsui E
    Kaneko H
    Fukao T
    Teramoto T
    Inoue R
    Watanabe M
    Aoki M
    Kasahara K
    Morimoto N
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    Źródło:
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2001 Aug; Vol. 31 (8), pp. 1189-93.
    Typ publikacji:
    Journal Article; Review
    MeSH Terms:
    Hypersensitivity, Immediate/*genetics
    Interleukin-12/*metabolism
    Mutation/*genetics
    Receptors, Interleukin/*genetics
    Animals ; Humans ; Hypersensitivity, Immediate/immunology ; Receptors, Interleukin-12
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Down-regulation of interleukin-12, interleukin-12R expression/activity mediates the switch from Th1 to Th2 granuloma response during murine Schistosomiasis mansoni.
    Autorzy:
    Todt JC; Department of Immunology and Microbiology, Wayne State, University School of Medicine, Detroit, MI 48201, USA.
    Whitfield JR
    Ivard SR
    Boros DL
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    Źródło:
    Scandinavian journal of immunology [Scand J Immunol] 2000 Oct; Vol. 52 (4), pp. 385-92.
    Typ publikacji:
    Journal Article; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Granuloma/*etiology
    Interleukin-12/*physiology
    Receptors, Interleukin/*physiology
    Schistosomiasis mansoni/*immunology
    Th1 Cells/*physiology
    Th2 Cells/*physiology
    Animals ; Down-Regulation ; Female ; Interleukin-10/physiology ; Interleukin-12/analysis ; Mice ; Mice, Inbred CBA ; Receptors, Interleukin/analysis ; Receptors, Interleukin-12 ; Tumor Necrosis Factor-alpha/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Role of beta1 and beta2 subunits of the interleukin-12 receptor in determining T helper 1/T helper 2 responses in vivo in the rat.
    Autorzy:
    Gillespie KM; Academic Renal Unit, and *Diabetes and Metabolism Unit, University of Bristol, Southmead Hospital, Bristol, UK.
    Szeto CC
    Betin VM
    Mathieson PW
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    Źródło:
    Immunology [Immunology] 2000 Jan; Vol. 99 (1), pp. 109-12.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Interleukin-12/*metabolism
    Receptors, Interleukin/*genetics
    Spleen/*immunology
    Th1 Cells/*immunology
    Th2 Cells/*immunology
    Animals ; Autoimmunity ; Base Sequence ; Gene Expression ; Mercuric Chloride/pharmacology ; Mice ; Molecular Sequence Data ; Protein Isoforms/genetics ; Rats ; Rats, Inbred BN ; Rats, Inbred Lew ; Receptors, Interleukin-12 ; Reverse Transcriptase Polymerase Chain Reaction ; Sequence Analysis, DNA ; Sequence Homology, Nucleic Acid
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-18 z 18

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