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Tytuł:
Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorder.
Autorzy:
Sun T; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Chen Q; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Mei J; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China.
Li Y; Department of Clinical Laboratory, Renmin Hospital of Wuhan University, Zhangzhidong Road, Wuchang District, Wuhan, 430060, Hubei, China. .
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Źródło:
BMC psychiatry [BMC Psychiatry] 2023 Oct 12; Vol. 23 (1), pp. 742. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Depressive Disorder, Major*/diagnosis
Receptors, Interleukin-6*
Female ; Humans ; Biomarkers ; Cytokine Receptor gp130 ; Estradiol ; Interleukin-6
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Autocrine Regulation of Interleukin-6 via the Activation of STAT3 and Akt in Cardiac Myxoma Cells.
Autorzy:
Jougasaki M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Takenoshita Y; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Umebashi K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Yamamoto M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sudou K; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Nakashima H; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Sonoda M; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
Kinjo T; Institute for Clinical Research, NHO Kagoshima Medical Center, Kagoshima 892-0853, Japan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/metabolism
Myxoma*/metabolism
Humans ; Cells, Cultured ; Proto-Oncogene Proteins c-akt/metabolism ; Receptors, Interleukin-6/metabolism ; Signal Transduction ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Upregulated microRNA-125b-5p in patients with asthma-COPD overlap mediates oxidative stress and late apoptosis via targeting IL6R/TRIAP1 signaling.
Autorzy:
Chang YP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Tsai YH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Chen YM; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Huang KT; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Lee CP; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Hsu PY; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Chen HC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.).
Lin MC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .
Chen YC; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .; Department of Respiratory Therapy, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong Dist., Kaohsiung, 83301, Taiwan (R.O.C.). .
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Źródło:
Respiratory research [Respir Res] 2024 Feb 01; Vol. 25 (1), pp. 64. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*/genetics
Asthma*/genetics
Asthma*/complications
MicroRNAs*/metabolism
Pulmonary Disease, Chronic Obstructive*/metabolism
Humans ; Allergens ; Intracellular Signaling Peptides and Proteins/metabolism ; Oxidative Stress/genetics ; Reactive Oxygen Species ; Receptors, Interleukin-6/metabolism ; RNA, Small Interfering/metabolism ; Male ; Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An epithelial gene signature of trans-IL-6 signaling defines a subgroup of type 2-low asthma.
Autorzy:
El-Husseini ZW; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
Khalenkow D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Lan A; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands.
van der Molen T; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Brightling C; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
Papi A; Department of Respiratory Medicine, University of Ferrara, Ferrara, Italy.
Rabe KF; Department of Medicine, Christian Albrechts University Kiel, Kiel and Lungen Clinic Grosshansdorf (Members of the German Center for Lung Research (DZL)), Grosshansdorf, Germany.
Siddiqui S; National Heart and Lung Institute, Imperial College and Imperial NIHR Biomedical Research Centre, London, UK.
Singh D; Medicines Evaluation Unit, Manchester University NHS Foundation Hospital Trust, University of Manchester, Manchester, UK.
Kraft M; Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, USA.
Beghe B; University of Modena and Reggio Emilia, AOU of Modena, Modena, Italy.
van den Berge M; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Gosliga D; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Nawijn MC; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.; Department of Pathology and Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.
Rose-John S; Biochemical Institute, University of Kiel, Kiel, Germany.
Koppelman GH; Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands.
Gosens R; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, The Netherlands. .; Department of Molecular Pharmacology, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, University of Groningen, 9713 AV, Groningen, The Netherlands. .
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Źródło:
Respiratory research [Respir Res] 2023 Dec 07; Vol. 24 (1), pp. 308. Date of Electronic Publication: 2023 Dec 07.
Typ publikacji:
Journal Article
MeSH Terms:
Asthma*/diagnosis
Asthma*/drug therapy
Asthma*/genetics
Interleukin-6*/metabolism
Humans ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Inflammation ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130.
Autorzy:
Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.
Cook SA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, 8 College Road, Singapore 169857, Singapore.; National Heart Centre Singapore, National Heart Research Institute Singapore, Singapore 169609, Singapore.; MRC-London Institute of Medical Sciences, Hammersmith Hospital Campus, London W6 8RF, UK.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 23; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 23.
Typ publikacji:
Journal Article
MeSH Terms:
Cytokines*/pharmacology
Interleukin-6*/metabolism
Mice ; Humans ; Animals ; Cytokine Receptor gp130/metabolism ; Signal Transduction ; Receptors, Interleukin-6
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα.
Autorzy:
Cai Z; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Department of Cardiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Tian S; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Klein T; Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Tu L; INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France.; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Geenen LW; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Koudstaal T; Department of Pulmonary Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
van den Bosch AE; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
de Rijke YB; Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Reiss IKM; Department of Pediatrics/Neonatology, Sophia Children's Hospital, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Boersma E; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Department of Clinical Epidemiology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
van der Ley C; Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Van Faassen M; Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Kema I; Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Duncker DJ; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
Boomars KA; Department of Pulmonary Medicine, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.
Tran-Lundmark K; Department of Experimental Medical Science, Lund University, Lund, Sweden.; Wallenberg Centre for Molecular Medicine, Lund University, Lund, Sweden.
Guignabert C; INSERM UMR_S 999, Hôpital Marie Lannelongue, Le Plessis-Robinson, France.; School of Medicine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Merkus D; Department of Cardiology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. .; Walter Brendel Center of Experimental Medicine (WBex), University Clinic Munich, LMU Munich, Munich, Germany. .; German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jul 19; Vol. 12 (1), pp. 12326. Date of Electronic Publication: 2022 Jul 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6*/metabolism
Kynurenine*/metabolism
Pulmonary Arterial Hypertension*/metabolism
Pulmonary Arterial Hypertension*/pathology
Receptors, Interleukin-6*/metabolism
Animals ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Humans ; Hypoxia/metabolism ; Kynurenic Acid/metabolism ; Monocrotaline ; Quinolinic Acid/metabolism ; Rats
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Relationship among serum levels of IL-6, sIL-6R, s gp130 and CD126 on T-cell in HIV-1 infected and uninfected men participating in the Los Angeles Multi-Center AIDS Cohort Study.
Autorzy:
Aziz N; Department of Epidemiology, Fielding School of Public Health, University California Los Angeles, Los Angeles, California, United States of America.
Shih R; Department of Epidemiology, Fielding School of Public Health, University California Los Angeles, Los Angeles, California, United States of America.
Alexopoulos N; Department of Epidemiology, Fielding School of Public Health, University California Los Angeles, Los Angeles, California, United States of America.
Jamieson BD; Department of Medicine, David Geffen School of Medicine, University California Los Angeles, Los Angeles, California, United States of America.
Mimiaga MJ; Department of Epidemiology, Fielding School of Public Health, University California Los Angeles, Los Angeles, California, United States of America.; Department of Psychiatry & Biobehavioral Sciences, David Geffen School of Medicine, University California Los Angeles, Los Angeles, California, United States of America.
Martinez-Maza O; Departments of Obstetrics & Gynecology and Microbiology Immunology and Molecular Genetics, UCLA, David Geffen School of Medicine, Los Angeles, California, United States of America.
Detels R; Department of Epidemiology, Fielding School of Public Health, University California Los Angeles, Los Angeles, California, United States of America.; Department of Medicine, David Geffen School of Medicine, University California Los Angeles, Los Angeles, California, United States of America.
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Źródło:
PloS one [PLoS One] 2023 Oct 09; Vol. 18 (10), pp. e0290702. Date of Electronic Publication: 2023 Oct 09 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
HIV-1*
Acquired Immunodeficiency Syndrome*
Male ; Humans ; Middle Aged ; Cytokine Receptor gp130 ; Interleukin-6 ; Cohort Studies ; Los Angeles ; T-Lymphocytes ; Receptors, Interleukin-6 ; Glycoproteins
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Biological sex is associated with heterogeneous responses to IL-6 receptor inhibitor treatment in COVID-19-A retrospective cohort study.
Autorzy:
Stein DF; Institute of Health Informatics, University College London, London, UK.
Foley C; Institute of Health Informatics, University College London, London, UK.
Byott M; Advanced Pathogen Diagnostics Unit, Department of Clinical Virology, UCL Hospitals NHS Trust, London, W1T 4EU, UK.
Nastouli E; Advanced Pathogen Diagnostics Unit, Department of Clinical Virology, UCL Hospitals NHS Trust, London, W1T 4EU, UK.; Department of Infection, Immunity and Inflammation, UCL Great Ormond Street Institute of Child Health, London, UK.
Ambler G; Department of Statistical Science, University College London, London, UK.
Arulkumaran N; Bloomsbury Institute of Intensive Care Medicine, University College London, Gower St, London, WC1E 6BT, UK. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 19; Vol. 13 (1), pp. 13504. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Humans ; Female ; Male ; Retrospective Studies ; SARS-CoV-2 ; Antibodies, Monoclonal/therapeutic use ; Receptors, Interleukin-6
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-6 receptor alpha and CD27 discriminate intratumoral T helper 17 subpopulations with distinct functional properties in a mouse lung cancer model.
Autorzy:
Liu C; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Xiong F; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Wang L; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Chen K; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Wu P; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Hua L; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
Zhang Z; The Department of Thoracic Surgery, Wuhan Third Hospital (Tongren Hospital of Wuhan University), Wuhan, Hubei Province, China.
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Źródło:
Immunity, inflammation and disease [Immun Inflamm Dis] 2021 Dec; Vol. 9 (4), pp. 1749-1758. Date of Electronic Publication: 2021 Sep 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Lung Neoplasms*/genetics
Receptors, Interleukin-6*/genetics
Animals ; Interferon-gamma ; Mice ; Th17 Cells ; Tumor Necrosis Factor Receptor Superfamily, Member 7
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Associations between blood inflammatory markers and bone mineral density and strength in the femoral neck: findings from the MIDUS II study.
Autorzy:
Huang Z; Department of General Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Xu Z; Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Wan R; Jiangxi Key Laboratory of Molecular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China.
Hu D; Rehabilitation Department, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. .
Huang Y; Rehabilitation Department, The Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 01; Vol. 13 (1), pp. 10662. Date of Electronic Publication: 2023 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bone Density*
Interleukin-10*
Adult ; Humans ; Cross-Sectional Studies ; Femur Neck/diagnostic imaging ; Interleukin-6 ; Interleukin-8 ; Retrospective Studies ; Tumor Necrosis Factor-alpha ; C-Reactive Protein ; Inflammation ; Receptors, Interleukin-6
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Association of Polymorphisms of IL-6 Pathway Genes (IL6, IL6R and IL6ST) with COVID-19 Severity in an Amazonian Population.
Autorzy:
Rodrigues FBB; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva R; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EFD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Brito MTFM; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
da Silva ALS; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Meira Leite M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Póvoa da Costa F; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Nazaré do Socorro de Almeida Viana M; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
de Sarges KML; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Cantanhede MHD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.
Veríssimo AOL; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Carvalho MDS; Hospital Adventista de Belém, Belém 66093-681, Brazil.
Henriques DF; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Silva CPD; Seção de Arbovirologia e Febres Hemorrágicas, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Nunes JAL; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Costa IB; Laboratório de Imunologia, Seção de Virologia, Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Viana GMR; Laboratório de Pesquisas Básicas em Malária, Seção de Parasitologia, Instituto Evandro Chagas, secretaria de Vigilância em Saúde, Ministério da Saúde do Brasil, Ananindeua 67000-000, Brazil.
Queiroz MAF; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lima SS; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Lopes JDC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Torres MKDS; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto IMVC; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Bichara CDA; Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários, Universidade Federal do Pará, Belém 58255-000, Brazil.; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Vallinoto ACR; Laboratório de Virologia, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
Santos EJMD; Laboratório de Genética de Doenças Complexas, Instituto de Ciências Biológicas, Universidade Federal do Pará, Belém 58255-000, Brazil.
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Źródło:
Viruses [Viruses] 2023 May 19; Vol. 15 (5). Date of Electronic Publication: 2023 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6*/genetics
COVID-19*/genetics
Humans ; Cross-Sectional Studies ; Receptors, Interleukin-6/genetics ; Genotype ; Polymorphism, Single Nucleotide ; Genetic Predisposition to Disease ; Cytokine Receptor gp130/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Increased IL-6 and Potential IL-6 trans-signalling in the airways after an allergen challenge.
Autorzy:
Esnault S; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, the University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Khosravi M; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, the University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Kelly EA; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, the University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Liu LY; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, the University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
Bochkov YA; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Tattersall MC; Department of Medicine, Division of Cardiovascular Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Jarjour NN; Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, the University of Wisconsin-Madison School of Medicine and Public Health, Madison, WI, USA.
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Źródło:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology [Clin Exp Allergy] 2021 Apr; Vol. 51 (4), pp. 564-573. Date of Electronic Publication: 2021 Feb 02.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Asthma/*metabolism
Cytokine Receptor gp130/*metabolism
Interleukin-6/*metabolism
Receptors, Interleukin-6/*metabolism
Allergens ; Ambrosia ; Animals ; Asthma/genetics ; Bronchial Provocation Tests ; Bronchoalveolar Lavage Fluid/chemistry ; Chemokine CCL2/metabolism ; Cytokine Receptor gp130/genetics ; Dander ; Female ; Humans ; Interleukin-6/genetics ; Male ; Pyroglyphidae ; RNA-Seq ; Receptors, Interleukin-6/genetics ; Respiratory Hypersensitivity/genetics ; Respiratory Hypersensitivity/metabolism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis.
Autorzy:
Blair JPM; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. .; ProScion, Herlev Hovedgade 205-207, 2730, Herlev, Denmark. .
Bay-Jensen AC; ImmunoScience, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Tang MH; ProScion, Herlev Hovedgade 205-207, 2730, Herlev, Denmark.
Frederiksen P; ImmunoScience, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Bager C; ProScion, Herlev Hovedgade 205-207, 2730, Herlev, Denmark.
Karsdal M; ImmunoScience, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark.
Brunak S; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Scientific reports [Sci Rep] 2020 Aug 18; Vol. 10 (1), pp. 13975. Date of Electronic Publication: 2020 Aug 18.
Typ publikacji:
Clinical Trial, Phase III; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies, Monoclonal, Humanized/*therapeutic use
Arthritis, Rheumatoid/*drug therapy
Receptors, Interleukin-6/*immunology
Adult ; Aged ; Antirheumatic Agents/therapeutic use ; Biomarkers, Pharmacological/blood ; Blood Sedimentation ; Disease Progression ; Drug Therapy, Combination/methods ; Female ; Humans ; Male ; Methotrexate/therapeutic use ; Middle Aged ; Receptors, Interleukin-6/metabolism ; Remission Induction ; Severity of Illness Index ; Treatment Outcome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance.
Autorzy:
O'Keefe RA; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, United States of America.
Bhola NE; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, United States of America.
Lee DS; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, United States of America.
Johnson DE; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, United States of America.
Grandis JR; Department of Otolaryngology-Head and Neck Surgery, University of California San Francisco, San Francisco, CA, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Jan 08; Vol. 15 (1), pp. e0227261. Date of Electronic Publication: 2020 Jan 08 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Drug Resistance, Neoplasm/*immunology
Head and Neck Neoplasms/*drug therapy
Interleukin-6/*metabolism
Receptors, Interleukin-6/*metabolism
Squamous Cell Carcinoma of Head and Neck/*drug therapy
Antibodies, Monoclonal, Humanized/pharmacology ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carbazoles ; Cell Line, Tumor ; Cetuximab/pharmacology ; Cetuximab/therapeutic use ; Cisplatin/pharmacology ; Cisplatin/therapeutic use ; Drug Resistance, Neoplasm/drug effects ; Drug Screening Assays, Antitumor ; ErbB Receptors/antagonists & inhibitors ; Gene Knockdown Techniques ; Head and Neck Neoplasms/immunology ; Head and Neck Neoplasms/pathology ; Humans ; Interleukin-6/genetics ; Interleukin-6/immunology ; Phosphorylation ; RNA, Small Interfering/metabolism ; Receptors, Interleukin-6/antagonists & inhibitors ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/immunology ; Recombinant Proteins/immunology ; STAT3 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Signal Transduction/immunology ; Squamous Cell Carcinoma of Head and Neck/immunology ; Squamous Cell Carcinoma of Head and Neck/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CPEB3 inhibits epithelial-mesenchymal transition by disrupting the crosstalk between colorectal cancer cells and tumor-associated macrophages via IL-6R/STAT3 signaling.
Autorzy:
Zhong Q; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China.
Fang Y; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China.
Lai Q; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China.
Wang S; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China.
He C; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China.
Li A; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China. .
Liu S; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China. .
Yan Q; Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, 1838th North Guangzhou Avenue, Guangzhou, 510515, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2020 Jul 11; Vol. 39 (1), pp. 132. Date of Electronic Publication: 2020 Jul 11.
Typ publikacji:
Journal Article
MeSH Terms:
Epithelial-Mesenchymal Transition*
Gene Expression Regulation, Neoplastic*
Colorectal Neoplasms/*pathology
RNA-Binding Proteins/*metabolism
Receptors, Interleukin-6/*metabolism
STAT3 Transcription Factor/*metabolism
Tumor-Associated Macrophages/*pathology
Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Cell Proliferation ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/metabolism ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Prognosis ; RNA-Binding Proteins/genetics ; Receptors, Interleukin-6/genetics ; STAT3 Transcription Factor/genetics ; Tumor Cells, Cultured ; Tumor Microenvironment ; Tumor-Associated Macrophages/metabolism ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study.
Autorzy:
Hamilton FW; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Infection Science, North Bristol NHS Trust, Bristol, United Kingdom.
Thomas M; Intensive Care Unit, North Bristol NHS Trust, Bristol, United Kingdom.
Arnold D; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom.
Palmer T; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
Moran E; Infection Science, North Bristol NHS Trust, Bristol, United Kingdom.
Mentzer AJ; Wellcome Centre For Human Genetics, University of Oxford, Oxford, United Kingdom.
Maskell N; Academic Respiratory Unit, University of Bristol, Bristol, United Kingdom.
Baillie K; Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom.
Summers C; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Hingorani A; UCL Institute for Cardiovascular Science, University College London, London, United Kingdom.; UCL BHF Research Accelerator, University College London, London, United Kingdom.; Health Data Research UK, London, United Kingdom.
MacGowan A; Infection Science, North Bristol NHS Trust, Bristol, United Kingdom.
Khandaker GM; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
Mitchell R; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
Davey Smith G; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
Ghazal P; Project Sepsis, Cardiff University, Cardiff, United Kingdom.
Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.
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Źródło:
PLoS medicine [PLoS Med] 2023 Jan 30; Vol. 20 (1), pp. e1004174. Date of Electronic Publication: 2023 Jan 30 (Print Publication: 2023).
Typ publikacji:
Meta-Analysis; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*
Sepsis*/drug therapy
Sepsis*/genetics
Humans ; Interleukin-6/genetics ; Hospitalization ; Receptors, Interleukin-6/genetics ; Mendelian Randomization Analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling.
Autorzy:
Flynn CM; Institute of Biochemistry, Kiel University, Kiel, Germany.
Garbers Y; Institute of Psychology, Kiel University, Kiel, Germany.
Lokau J; Institute of Biochemistry, Kiel University, Kiel, Germany.; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany.
Wesch D; Institute of Immunology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany.
Schulte DM; Department of Internal Medicine 1, Kiel University, Kiel, Germany.
Laudes M; Department of Internal Medicine 1, Kiel University, Kiel, Germany.
Lieb W; Institute of Epidemiology, Kiel University, Kiel, Germany.
Aparicio-Siegmund S; Institute of Biochemistry, Kiel University, Kiel, Germany.
Garbers C; Institute of Biochemistry, Kiel University, Kiel, Germany. .; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2019 May 13; Vol. 9 (1), pp. 7306. Date of Electronic Publication: 2019 May 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Interleukin-6/*metabolism
MAP Kinase Signaling System/*immunology
Receptors, Interleukin-6/*metabolism
Sepsis/*immunology
Toll-Like Receptor 2/*metabolism
ADAM10 Protein/metabolism ; ADAM17 Protein/metabolism ; Alternative Splicing/immunology ; Amyloid Precursor Protein Secretases/metabolism ; Case-Control Studies ; Cohort Studies ; Healthy Volunteers ; Humans ; Interleukin-6/blood ; Leukocytes, Mononuclear/immunology ; Leukocytes, Mononuclear/metabolism ; Membrane Proteins/metabolism ; Monocytes/immunology ; Monocytes/metabolism ; Primary Cell Culture ; RNA, Messenger/metabolism ; Receptors, Interleukin-6/blood ; Receptors, Interleukin-6/genetics ; Sepsis/blood ; THP-1 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Circadian gene Rev-erbα influenced by sleep conduces to pregnancy by promoting endometrial decidualization via IL-6-PR-C/EBPβ axis.
Autorzy:
Cui L; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Xu F; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Xu C; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Ding Y; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China.; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China.
Wang S; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China. .; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China. .; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, ZhaoZhou Road 413, Shanghai, 200011, China. .
Du M; NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, Shanghai, 200090, China. .; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases, Shanghai, 200090, China. .; Laboratory for Reproductive Immunology, Hospital of Obstetrics and Gynecology, Fudan University Shanghai Medical College, ZhaoZhou Road 413, Shanghai, 200011, China. .; State Key Laboratory of Quality Research in Chinese Medicine and School of Pharmacy, Macau University of Science and Technology, Macau, SAR, China. .; Department of Obstetrics and Gynecology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, 510180, China. .
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Źródło:
Journal of biomedical science [J Biomed Sci] 2022 Nov 24; Vol. 29 (1), pp. 101. Date of Electronic Publication: 2022 Nov 24.
Typ publikacji:
Journal Article
MeSH Terms:
Interleukin-6*/genetics
Nuclear Receptor Subfamily 1, Group D, Member 1*/genetics
Nuclear Receptor Subfamily 1, Group D, Member 1*/metabolism
Animals ; Female ; Mice ; Pregnancy ; Circadian Rhythm/genetics ; Receptors, Interleukin-6 ; Sleep ; CCAAT-Enhancer-Binding Protein-beta/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interleukin-6 signaling requires EHD1-mediated alteration of membrane rafts.
Autorzy:
Woo JH; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SJ; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.
Park SM; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Joe EH; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.; Center for Convergence Research of Neurological Disorders, Ajou University School of Medicine, Suwon, Korea.
Jou I; Inflamm-aging Translational Research Center, Ajou University School of Medicine, Suwon, Korea.; Department of Pharmacology, Ajou University School of Medicine, Suwon, Korea.
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Źródło:
The FEBS journal [FEBS J] 2022 Oct; Vol. 289 (19), pp. 5914-5932. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cholera Toxin*/metabolism
Interleukin-6*/genetics
Interleukin-6*/metabolism
Cholesterol/metabolism ; Cytokine Receptor gp130/genetics ; Cytokine Receptor gp130/metabolism ; Membrane Microdomains/metabolism ; Membrane Proteins/metabolism ; Receptors, Interleukin-6/genetics ; Receptors, Interleukin-6/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Immuno-pathogenesis of neuromyelitis optica and emerging therapies.
Autorzy:
Chihara N; Division of Neurology, Kobe University Graduate School of Medicine, Kobe, Japan.
Yamamura T; Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan. .
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Źródło:
Seminars in immunopathology [Semin Immunopathol] 2022 Sep; Vol. 44 (5), pp. 599-610. Date of Electronic Publication: 2022 May 30.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Neuromyelitis Optica*/etiology
Neuromyelitis Optica*/therapy
Aquaporin 4/metabolism ; Aquaporin 4/therapeutic use ; Autoantibodies ; Biomarkers ; Chemokines/metabolism ; Complement C5/metabolism ; Complement C5/therapeutic use ; Cytokines/metabolism ; Humans ; Interleukin-6/metabolism ; Receptors, Interleukin-6/metabolism ; Receptors, Interleukin-6/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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