Temat: "Receptors, Purinergic P2Y" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: P2Y Purinergic Receptors, Endothelial Dysfunction, and Cardiovascular Diseases.
Autorzy:: Strassheim D; The Department of Medicine Cardiovascular and Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA.
Verin A; Vascular Biology Center, Augusta University, Augusta, GA 30912, USA.
Batori R; Vascular Biology Center, Augusta University, Augusta, GA 30912, USA.
Nijmeh H; The Department of Pediatrics, Division of Critical Care Medicine, University of Colorado Denver, Aurora, CO 80045, USA.
Burns N; The Department of Medicine Cardiovascular and Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA.
Kovacs-Kasa A; Vascular Biology Center, Augusta University, Augusta, GA 30912, USA.
Umapathy NS; Center for Blood Disorders, Augusta University, Augusta, GA 30912, USA.
Kotamarthi J; The Department of BioMedical Engineering, University of Wisconsin, Madison, WI 53706, USA.
Gokhale YS; The Department of BioMedical Engineering, University of Wisconsin, Madison, WI 53706, USA.
Karoor V; The Department of Medicine Cardiovascular and Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA.
Stenmark KR; The Department of Medicine Cardiovascular and Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA.; The Department of Pediatrics, Division of Critical Care Medicine, University of Colorado Denver, Aurora, CO 80045, USA.
Gerasimovskaya E; The Department of Medicine Cardiovascular and Pulmonary Research Laboratory, University of Colorado Denver, Aurora, CO 80045, USA.; The Department of Pediatrics, Division of Critical Care Medicine, University of Colorado Denver, Aurora, CO 80045, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Sep 18; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cardiovascular Diseases/*metabolism
Endothelial Cells/*metabolism
Endothelium/*metabolism
Neovascularization, Pathologic/*metabolism
Receptors, Purinergic P2Y/*metabolism
Signal Transduction/*physiology
Animals ; Endothelium/pathology ; Humans ; Inflammation/metabolism ; Inflammation/physiopathology ; Oxidative Stress/physiology ; Receptors, Purinergic P2Y/physiology

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Skocz do pozycji: 2.

Tytuł:: Role of UDP-Sugar Receptor P2Y 14 in Murine Osteoblasts.
Autorzy:: Mikolajewicz N; Shriners Hospital for Children, Montreal, QC H4A 0A9, Canada.; Faculty of Dentistry, McGill University, Montreal, QC H3A 1G1, Canada.
Komarova SV; Shriners Hospital for Children, Montreal, QC H4A 0A9, Canada.; Faculty of Dentistry, McGill University, Montreal, QC H3A 1G1, Canada.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 15; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 15.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Proliferation/*genetics
Osteoblasts/*metabolism
Osteogenesis/*genetics
Purinergic Antagonists/*pharmacology
Receptors, Purinergic P2Y/*metabolism
Signal Transduction/*genetics
Uridine Diphosphate Sugars/*metabolism
Adenosine Diphosphate/pharmacology ; Adenosine Triphosphate/pharmacology ; Animals ; Bone Density/genetics ; CRISPR-Cas Systems ; Calcium/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Cells, Cultured ; Cyclic AMP/metabolism ; Gene Knockout Techniques ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Osteogenesis/drug effects ; Phosphorylation ; Purinergic Antagonists/metabolism ; Receptors, Purinergic P2Y/genetics ; Signal Transduction/drug effects ; Uridine Diphosphate Glucose/metabolism ; Uridine Diphosphate Glucose/pharmacology ; Uridine Diphosphate Sugars/pharmacology

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Skocz do pozycji: 3.

Tytuł:: Purinergic receptor mediated calcium signalling in urothelial cells.
Autorzy:: Chess-Williams R; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia.
Sellers DJ; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia.
Brierley SM; Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, 5042, Australia.; Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), North Terrace, Adelaide, South Australia, 5000, Australia.; Centre for Nutrition and Gastrointestinal Diseases, Discipline of Medicine, University of Adelaide, North Terrace, Adelaide, South Australia, 5000, Australia.
Grundy D; Department of Biomedical Science, University of Sheffield, Sheffield, United Kingdom.
Grundy L; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, Australia. .; Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, 5042, Australia. .; Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), North Terrace, Adelaide, South Australia, 5000, Australia. .; Centre for Nutrition and Gastrointestinal Diseases, Discipline of Medicine, University of Adelaide, North Terrace, Adelaide, South Australia, 5000, Australia. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Nov 06; Vol. 9 (1), pp. 16101. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium/*metabolism
Receptors, Purinergic P2X/*metabolism
Receptors, Purinergic P2Y/*metabolism
Urothelium/*metabolism
Adenosine Triphosphate/metabolism ; Animals ; Calcium Signaling ; Epithelial Cells/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Receptors, Purinergic P2X/genetics ; Receptors, Purinergic P2Y/genetics ; Urothelium/cytology

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Skocz do pozycji: 4.

Tytuł:: The Interplay of Endothelial P2Y Receptors in Cardiovascular Health: From Vascular Physiology to Pathology.
Autorzy:: Cabou C; I2MC, University of Toulouse, INSERM, UPS, 31000 Toulouse, France.; Department of Human Physiology and Physiopathology, Faculty of Pharmacy, UPS, 31000 Toulouse, France.
Martinez LO; I2MC, University of Toulouse, INSERM, UPS, 31000 Toulouse, France.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 May 24; Vol. 23 (11). Date of Electronic Publication: 2022 May 24.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Cardiovascular Diseases*/metabolism
Cardiovascular System*/metabolism
Animals ; Endothelial Cells/metabolism ; Endothelium/metabolism ; Mice ; Nucleotides ; Receptors, Purinergic P2Y ; Vasodilation/physiology

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Skocz do pozycji: 5.

Tytuł:: Acute leukemia cells resistant to PI3K/mTOR inhibition display upregulation of P2RY14 expression.
Autorzy:: Shah K; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Moharram SA; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden.
Kazi JU; Division of Translational Cancer Research, Department of Laboratory Medicine, Lund University, Lund, Sweden.; Pokaż więcej
Źródło:: Clinical epigenetics [Clin Epigenetics] 2018 Jun 19; Vol. 10, pp. 83. Date of Electronic Publication: 2018 Jun 19 (Print Publication: 2018).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
Precursor Cell Lymphoblastic Leukemia-Lymphoma/*metabolism
Receptors, Purinergic P2Y/*metabolism
Animals ; Cell Line, Tumor ; Humans ; MAP Kinase Signaling System/genetics ; Morpholines/pharmacology ; Phosphoinositide-3 Kinase Inhibitors ; Phosphorylation ; Receptors, Purinergic P2Y/genetics ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Triazines/pharmacology ; Up-Regulation

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Skocz do pozycji: 6.

Tytuł:: Extracellular Nucleotides Affect the Proangiogenic Behavior of Fibroblasts, Keratinocytes, and Endothelial Cells.
Autorzy:: Węgłowska E; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Koziołkiewicz M; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Kamińska D; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Grobelski B; Department of Experimental Surgery, Medical University of Lodz, 93-513 Lodz, Poland.
Pawełczak D; Department of Experimental Surgery, Medical University of Lodz, 93-513 Lodz, Poland.
Kołodziejczyk M; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Bielecki S; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.
Gendaszewska-Darmach E; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 2/22, 90-537 Lodz, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 27; Vol. 23 (1). Date of Electronic Publication: 2021 Dec 27.
Typ publikacji:: Journal Article
MeSH Terms:: Neovascularization, Physiologic*/drug effects
Neovascularization, Physiologic*/genetics
Extracellular Space/*chemistry
Fibroblasts/*physiology
Human Umbilical Vein Endothelial Cells/*physiology
Keratinocytes/*physiology
Nucleotides/*pharmacology
Adult ; Cell Proliferation/drug effects ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Gene Expression Regulation/drug effects ; HaCaT Cells ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Keratinocytes/drug effects ; Keratinocytes/metabolism ; Phosphorothioate Oligonucleotides/pharmacology ; Receptors, Purinergic P2Y/metabolism ; Vascular Endothelial Growth Factor A/metabolism

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Skocz do pozycji: 7.

Tytuł:: Suppression of TRPV1/TRPM8/P2Y Nociceptors by Withametelin via Downregulating MAPK Signaling in Mouse Model of Vincristine-Induced Neuropathic Pain.
Autorzy:: Khan A; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Shal B; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Khan AU; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Ullah R; Department of Pharmacy, University of Peshawar, Peshawar 25120, Pakistan.
Baig MW; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Ul Haq I; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Seo EK; Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul 03760, Korea.
Khan S; Pharmacological Sciences Research Lab, Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 04; Vol. 22 (11). Date of Electronic Publication: 2021 Jun 04.
Typ publikacji:: Journal Article
MeSH Terms:: MAP Kinase Signaling System/*drug effects
Neuralgia/*drug therapy
Nociceptors/*drug effects
Phytosterols/*pharmacology
Receptors, Purinergic P2Y/*chemistry
TRPM Cation Channels/*antagonists & inhibitors
TRPV Cation Channels/*antagonists & inhibitors
Vincristine/*toxicity
Animals ; Antineoplastic Agents, Phytogenic/toxicity ; Male ; Mice ; Mice, Inbred BALB C ; Neuralgia/chemically induced ; Neuralgia/metabolism ; Rats

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Skocz do pozycji: 8.

Tytuł:: Control of Macrophage Inflammation by P2Y Purinergic Receptors.
Autorzy:: Klaver D; Immunotherapy Unit, Department of Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Thurnher M; Immunotherapy Unit, Department of Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria.; Pokaż więcej
Źródło:: Cells [Cells] 2021 May 04; Vol. 10 (5). Date of Electronic Publication: 2021 May 04.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:: Inflammation/*immunology
Macrophages/*immunology
Receptors, Purinergic P2Y/*metabolism
Stress, Physiological/*immunology
Animals ; COVID-19/blood ; COVID-19/immunology ; Humans ; Immunologic Surveillance/drug effects ; Immunologic Surveillance/immunology ; Inflammation/blood ; Inflammation/drug therapy ; Macrophages/metabolism ; Mice ; Neoplasms/blood ; Neoplasms/drug therapy ; Neoplasms/immunology ; Purinergic P2Y Receptor Agonists/pharmacology ; Purinergic P2Y Receptor Agonists/therapeutic use ; Purinergic P2Y Receptor Antagonists/pharmacology ; Purinergic P2Y Receptor Antagonists/therapeutic use ; Receptors, Tumor Necrosis Factor/metabolism ; STAT1 Transcription Factor/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Tumor Necrosis Factor-alpha/metabolism ; COVID-19 Drug Treatment

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Skocz do pozycji: 9.

Tytuł:: Astrocytes respond to a neurotoxic Aβ fragment with state-dependent Ca alteration and multiphasic transmitter release.
Autorzy:: Pham C; Institute of Biology Paris Seine, Neuroscience Paris Seine, CNRS UMR8246, INSERM U1130, Sorbonne Université, 75005, Paris, France.
Hérault K; INSERM/UdA U1107 Neuro-Dol, Université Clermont Auvergne, 63100, Clermont-Ferrand, France.
Oheim M; Saints-Pères Paris Institute for the Neurosciences (SPPIN), CNRS UMR8003, Université de Paris, 75006, Paris, France.
Maldera S; Institute of Biology Paris Seine, Neuroscience Paris Seine, CNRS UMR8246, INSERM U1130, Sorbonne Université, 75005, Paris, France.
Vialou V; Institute of Biology Paris Seine, Neuroscience Paris Seine, CNRS UMR8246, INSERM U1130, Sorbonne Université, 75005, Paris, France.
Cauli B; Institute of Biology Paris Seine, Neuroscience Paris Seine, CNRS UMR8246, INSERM U1130, Sorbonne Université, 75005, Paris, France.
Li D; Institute of Biology Paris Seine, Neuroscience Paris Seine, CNRS UMR8246, INSERM U1130, Sorbonne Université, 75005, Paris, France. .; Pokaż więcej
Źródło:: Acta neuropathologica communications [Acta Neuropathol Commun] 2021 Mar 16; Vol. 9 (1), pp. 44. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Alzheimer Disease/*metabolism
Amyloid beta-Peptides/*pharmacology
Astrocytes/*drug effects
Calcium/*metabolism
Calcium Signaling/*drug effects
Peptide Fragments/*pharmacology
3',5'-Cyclic-AMP Phosphodiesterases/metabolism ; Animals ; Animals, Newborn ; Astrocytes/metabolism ; Astrocytes/pathology ; Astrocytes/physiology ; Cells, Cultured ; Disease Models, Animal ; Glutamic Acid/metabolism ; Mice ; Neurotoxicity Syndromes/etiology ; Neurotoxicity Syndromes/metabolism ; Neurotoxicity Syndromes/physiopathology ; Peptide Fragments/metabolism ; Plasma Membrane Calcium-Transporting ATPases/metabolism ; Receptors, Purinergic P2Y/metabolism

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Skocz do pozycji: 10.

Tytuł:: Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer.
Autorzy:: Duan S; Department of Pharmacology, School of Medicine, University of Nevada Reno, Reno, NV 89557, USA.; Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ 85724, USA.
Nordmeier S; Department of Pharmacology, School of Medicine, University of Nevada Reno, Reno, NV 89557, USA.
Byrnes AE; Department of Pharmacology, School of Medicine, University of Nevada Reno, Reno, NV 89557, USA.
Buxton ILO; Department of Pharmacology, School of Medicine, University of Nevada Reno, Reno, NV 89557, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 09; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 09.
Typ publikacji:: Journal Article
MeSH Terms:: Signal Transduction*
Extracellular Vesicles/*pathology
Lung Neoplasms/*secondary
Receptors, Purinergic P2Y/*metabolism
Triple Negative Breast Neoplasms/*pathology
Animals ; Cell Line ; Cell Line, Tumor ; Cell Movement ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Extracellular Vesicles/metabolism ; Female ; Humans ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Mice, SCID ; NM23 Nucleoside Diphosphate Kinases/metabolism ; Triple Negative Breast Neoplasms/metabolism ; Tumor Microenvironment ; Mice

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Skocz do pozycji: 11.

Tytuł:: Multidrug Resistance-Associated Protein 2 Expression Is Upregulated by Adenosine 5'-Triphosphate in Colorectal Cancer Cells and Enhances Their Survival to Chemotherapeutic Drugs.
Autorzy:: Vinette V; Department of Anatomy and Cell Biology, Faculté de Médecine et des Sciences de la Santé, Pavillon de Recherche Appliquée sur le Cancer, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Placet M; Department of Anatomy and Cell Biology, Faculté de Médecine et des Sciences de la Santé, Pavillon de Recherche Appliquée sur le Cancer, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Arguin G; Department of Anatomy and Cell Biology, Faculté de Médecine et des Sciences de la Santé, Pavillon de Recherche Appliquée sur le Cancer, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Gendron FP; Department of Anatomy and Cell Biology, Faculté de Médecine et des Sciences de la Santé, Pavillon de Recherche Appliquée sur le Cancer, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Aug 21; Vol. 10 (8), pp. e0136080. Date of Electronic Publication: 2015 Aug 21 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Adenosine Triphosphate/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Multidrug Resistance-Associated Proteins/*genetics
Receptors, Purinergic P2Y/*genetics
Antineoplastic Agents/pharmacology ; Caco-2 Cells ; Cell Survival/drug effects ; Cisplatin/pharmacology ; Doxorubicin/pharmacology ; Drug Resistance, Neoplasm/genetics ; Etoposide/pharmacology ; HEK293 Cells ; Humans ; Multidrug Resistance-Associated Protein 2 ; Multidrug Resistance-Associated Proteins/antagonists & inhibitors ; Multidrug Resistance-Associated Proteins/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Receptors, Purinergic P2Y/metabolism ; Signal Transduction ; Transcription, Genetic

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Skocz do pozycji: 12.

Tytuł:: P2X and P2Y receptors—role in the pathophysiology of the nervous system.
Autorzy:: Puchałowicz K; Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, 72 Powstańców Wielkopolskich Street, Szczecin 70-111, Poland. .
Tarnowski M; Department of Physiology, Pomeranian Medical University, 72 Powstańców Wielkopolskich Street, Szczecin 70-111, Poland. .
Baranowska-Bosiacka I; Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, 72 Powstańców Wielkopolskich Street, Szczecin 70-111, Poland. .
Chlubek D; Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, 72 Powstańców Wielkopolskich Street, Szczecin 70-111, Poland. .
Dziedziejko V; Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, 72 Powstańców Wielkopolskich Street, Szczecin 70-111, Poland. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2014 Dec 18; Vol. 15 (12), pp. 23672-704. Date of Electronic Publication: 2014 Dec 18.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Nervous System Diseases/*metabolism
Receptors, Purinergic P2X/*metabolism
Receptors, Purinergic P2Y/*metabolism
Animals ; Humans ; Nervous System Diseases/drug therapy ; Nervous System Diseases/genetics ; Purinergic P2 Receptor Agonists/pharmacology ; Purinergic P2 Receptor Agonists/therapeutic use ; Purinergic P2 Receptor Antagonists/pharmacology ; Purinergic P2 Receptor Antagonists/therapeutic use ; Receptors, Purinergic P2X/chemistry ; Receptors, Purinergic P2X/genetics ; Receptors, Purinergic P2Y/chemistry ; Receptors, Purinergic P2Y/genetics

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Skocz do pozycji: 13.

Tytuł:: Role of P2Y Receptors in Platelet Extracellular Vesicle Release.
Autorzy:: Gąsecka A; 1st Chair and Department of Cardiology, Medical University of Warsaw, 02-106 Warsaw, Poland.; Laboratory Experimental Clinical Chemistry, and Vesicle Observation Center, Amsterdam UMC, University of Amsterdam, 1012 WX Amsterdam, The Netherlands.
Rogula S; 1st Chair and Department of Cardiology, Medical University of Warsaw, 02-106 Warsaw, Poland.
Eyileten C; Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Postuła M; Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Jaguszewski MJ; 1st Department of Cardiology, Medical University of Gdansk, 80-210 Gdańsk, Poland.
Kochman J; 1st Chair and Department of Cardiology, Medical University of Warsaw, 02-106 Warsaw, Poland.
Mazurek T; 1st Chair and Department of Cardiology, Medical University of Warsaw, 02-106 Warsaw, Poland.
Nieuwland R; Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Filipiak KJ; 1st Chair and Department of Cardiology, Medical University of Warsaw, 02-106 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 23; Vol. 21 (17). Date of Electronic Publication: 2020 Aug 23.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Blood Platelets/*cytology
Cardiovascular Diseases/*diagnosis
Extracellular Vesicles/*metabolism
Receptors, Purinergic P2Y/*metabolism
Animals ; Blood Platelets/metabolism ; Cardiovascular Diseases/therapy ; Humans ; Platelet Activation ; Prognosis ; Signal Transduction

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Skocz do pozycji: 14.

Tytuł:: Contribution of P2X4 Receptors to CNS Function and Pathophysiology.
Autorzy:: Montilla A; Department of Neuroscience, University of the Basque Country (UPV/EHU), Achucarro Basque Center for Neuroscience and Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 48940 Leioa, Spain.
Mata GP; Department of Neuroscience, University of the Basque Country (UPV/EHU), Achucarro Basque Center for Neuroscience and Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 48940 Leioa, Spain.
Matute C; Department of Neuroscience, University of the Basque Country (UPV/EHU), Achucarro Basque Center for Neuroscience and Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 48940 Leioa, Spain.
Domercq M; Department of Neuroscience, University of the Basque Country (UPV/EHU), Achucarro Basque Center for Neuroscience and Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), 48940 Leioa, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Aug 03; Vol. 21 (15). Date of Electronic Publication: 2020 Aug 03.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Adenosine Triphosphate/*genetics
Central Nervous System Diseases/*genetics
Receptors, Purinergic P2X4/*genetics
Receptors, Purinergic P2Y/*genetics
Cell Communication/genetics ; Central Nervous System/metabolism ; Central Nervous System/pathology ; Central Nervous System Diseases/metabolism ; Central Nervous System Diseases/pathology ; Humans ; Microglia/pathology ; Neuronal Plasticity/genetics

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Skocz do pozycji: 15.

Tytuł:: Role of peripheral purinoceptors in the development of bee venom-induced nociception: a behavioural and electrophysiological study in rats.
Autorzy:: Li L; Department of Physiology and Pathophysiology, School of Medicine, Xi'an Jiaotong University Health Science Center, Xi'an, China.
Luo R
Fan P
Guo Y
Wang HS
Ma SJ
Zhao Y; Pokaż więcej
Źródło:: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2014 Nov; Vol. 41 (11), pp. 902-10.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bee Venoms/*pharmacology
Behavior, Animal/*drug effects
Nociceptive Pain/*physiopathology
Receptors, Purinergic P2X/*physiology
Receptors, Purinergic P2Y/*physiology
Sensory Receptor Cells/*drug effects
Action Potentials/drug effects ; Animals ; Behavior, Animal/physiology ; Ganglia, Spinal/drug effects ; Ganglia, Spinal/metabolism ; Male ; Nociceptive Pain/chemically induced ; Nociceptive Pain/metabolism ; Pain Measurement ; Pain Threshold/drug effects ; Purinergic P2X Receptor Antagonists/pharmacology ; Purinergic P2Y Receptor Antagonists/pharmacology ; Rats, Sprague-Dawley ; Receptors, Purinergic P2X/metabolism ; Receptors, Purinergic P2Y/metabolism ; Sensory Receptor Cells/metabolism

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Skocz do pozycji: 16.

Tytuł:: Extracellular Nucleotides Selectively Induce Migration of Chondrocytes and Expression of Type II Collagen.
Autorzy:: Szustak M; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland.
Gendaszewska-Darmach E; Institute of Molecular and Industrial Biotechnology, Faculty of Biotechnology and Food Sciences, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 23; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 23.
Typ publikacji:: Journal Article
MeSH Terms:: Cell Movement/*drug effects
Chondrocytes/*metabolism
Collagen Type II/*biosynthesis
Gene Expression Regulation/*drug effects
Nucleotides/*pharmacology
Animals ; Cartilage/metabolism ; Cell Line ; Extracellular Matrix/metabolism ; Mice ; Receptors, Purinergic P2Y/metabolism

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Tytuł:: In Silico Drug Design for Purinergic GPCRs: Overview on Molecular Dynamics Applied to Adenosine and P2Y Receptors.
Autorzy:: Salmaso V; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Jacobson KA; Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2020 May 26; Vol. 10 (6). Date of Electronic Publication: 2020 May 26.
Typ publikacji:: Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms:: Drug Design*
Molecular Dynamics Simulation*
Fibrinolytic Agents/*pharmacology
Neuroprotective Agents/*pharmacology
Receptors, Purinergic P1/*metabolism
Receptors, Purinergic P2Y/*metabolism
Algorithms ; Fibrinolytic Agents/chemistry ; Humans ; Neuroprotective Agents/chemistry

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Skocz do pozycji: 18.

Tytuł:: Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y 12 Inhibition.
Autorzy:: Braza-Boïls A; King's British Heart Foundation Centre, King's College London, London SE5 9NU, UK.; Health Research Institute La Fe, 46026 Valencia, Spain.
Barwari T; King's British Heart Foundation Centre, King's College London, London SE5 9NU, UK.
Gutmann C; King's British Heart Foundation Centre, King's College London, London SE5 9NU, UK.
Thomas MR; Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B15 2TT, UK.
Judge HM; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2RX, UK.
Joshi A; King's British Heart Foundation Centre, King's College London, London SE5 9NU, UK.
Pechlaner R; Department of Neurology, Medical University Innsbruck, Innsbruck 6020, Austria.
Shankar-Hari M; Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Ajjan RA; Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds LS2 9JT, UK.
Sabroe I; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2RX, UK.
Storey RF; Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield S10 2RX, UK.
Mayr M; King's British Heart Foundation Centre, King's College London, London SE5 9NU, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 21; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 21.
Typ publikacji:: Journal Article
MeSH Terms:: Circulating MicroRNA*
Platelet Activation*
Blood Platelets/*metabolism
Endotoxemia/*blood
Endotoxemia/*etiology
Leukocytes/*metabolism
MicroRNAs/*genetics
Receptors, Purinergic P2Y/*metabolism
Adolescent ; Adult ; Biomarkers ; Blood Platelets/drug effects ; Endotoxemia/drug therapy ; Gene Expression Regulation ; Humans ; Male ; MicroRNAs/blood ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Aggregation Inhibitors/therapeutic use ; Sepsis/blood ; Sepsis/drug therapy ; Sepsis/etiology ; Young Adult

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Tytuł:: c-Jun, Foxo3a, and c-Myc Transcription Factors are Key Regulators of ATP-Mediated Angiogenic Responses in Pulmonary Artery Vasa Vasorum Endothelial Cells.
Autorzy:: Strassheim D; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.
Karoor V; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.
Nijmeh H; University of Colorado Denver, Department of Pediatrics, Division of Critical Care Medicine, Aurora, CO 80045, USA.
Weston P; University of Colorado Denver, Department of Pediatrics, Division of Critical Care Medicine, Aurora, CO 80045, USA.
Lapel M; University of Colorado Denver, Department of Pediatrics, Division of Critical Care Medicine, Aurora, CO 80045, USA.
Schaack J; University of Colorado Denver, Department of Microbiology, Aurora, CO 80045, USA.
Sullivan T; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.
Dempsey EC; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.; Rocky Mountain Regional VA Medical Center, Aurora, CO 80045, USA.
Stenmark KR; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.; University of Colorado Denver, Department of Pediatrics, Division of Critical Care Medicine, Aurora, CO 80045, USA.
Gerasimovskaya E; University of Colorado Denver, Department of Medicine Cardiovascular and Pulmonary Research Laboratory, Aurora, CO 80045, USA.; University of Colorado Denver, Department of Pediatrics, Division of Critical Care Medicine, Aurora, CO 80045, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Feb 11; Vol. 9 (2). Date of Electronic Publication: 2020 Feb 11.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: Forkhead Box Protein O3/*genetics
Hypertension, Pulmonary/*genetics
JNK Mitogen-Activated Protein Kinases/*genetics
Proto-Oncogene Proteins c-myc/*genetics
Vasa Vasorum/*growth & development
Adenosine Triphosphate/metabolism ; Endothelial Cells/metabolism ; Endothelial Cells/pathology ; Humans ; Hypertension, Pulmonary/pathology ; Neovascularization, Pathologic ; Phosphatidylinositol 3-Kinases/genetics ; Proto-Oncogene Proteins c-akt/genetics ; Pulmonary Artery/growth & development ; Pulmonary Artery/metabolism ; Pulmonary Artery/pathology ; Receptors, Purinergic P2Y/genetics ; Signal Transduction/genetics ; TOR Serine-Threonine Kinases/genetics ; Vasa Vasorum/pathology ; Vascular Remodeling/genetics

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Tytuł:: P2Y purinoceptors induce changes in intracellular calcium in acinar cells of rat lacrimal glands.
Autorzy:: Kamada Y; Department of Anatomy (Cell Biology), Iwate Medical University, 2-1-1 Nishitokuda, Yahaba, Iwate 028-3694, Japan.
Saino T
Oikawa M
Kurosaka D
Satoh Y; Pokaż więcej
Źródło:: Histochemistry and cell biology [Histochem Cell Biol] 2012 Jan; Vol. 137 (1), pp. 97-106. Date of Electronic Publication: 2011 Nov 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Calcium Signaling*
Acinar Cells/*metabolism
Calcium/*metabolism
Lacrimal Apparatus/*cytology
Receptors, Purinergic P2Y/*metabolism
Animals ; Male ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Rats ; Rats, Wistar ; Receptors, Purinergic P2Y/genetics

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