Temat: "Receptors, Retinoic Acid" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: RAR-Dependent and RAR-Independent RXR Signaling in Stem-like Glioma Cells.
Autorzy:: Dabrock A; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Ernesti N; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Will F; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Rana M; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Leinung N; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Ehrich P; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.
Tronnier V; Department of Neurosurgery, University Clinic Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.
Zechel C; Laboratory of Experimental Neuro-Oncology, Center of Brain, Behavior and Metabolism, University Lübeck, Marie-Curie Strasse 66, D-23562 Lübeck, Germany.; Department of Neurosurgery, University Clinic Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, D-23538 Lübeck, Germany.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 17; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Receptors, Retinoic Acid*/metabolism
Glioma*/genetics
Adult ; Humans ; Retinoids/pharmacology ; Tretinoin/pharmacology ; Retinoid X Receptors ; Stem Cells/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: Discovery of novel RARα agonists using pharmacophore-based virtual screening, molecular docking, and molecular dynamics simulation studies.
Autorzy:: Ghorayshian A; Department of Cell and Molecular Biology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran.
Danesh M; Functional Genomics & System Biology Group, Department of Bioinformatics, Biocenter, Am Hubland, University of Wuerzburg, Wuerzburg, Germany.
Mostashari-Rad T; Department of Artificial Intelligence, Smart University of Medical Sciences, Tehran, Iran.
Fassihi A; Department of Medicinal Chemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2023 Aug 24; Vol. 18 (8), pp. e0289046. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).
Typ publikacji:: Journal Article
MeSH Terms:: Molecular Dynamics Simulation*
Pharmacophore*
Receptors, Retinoic Acid*/agonists
Ligands ; Molecular Docking Simulation

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Hepatocyte Nuclear Factor 4α (HNF4α) Plays a Controlling Role in Expression of the Retinoic Acid Receptor β ( RARβ ) Gene in Hepatocytes.
Autorzy:: Zolfaghari R; Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA.
Bonzo JA; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Gonzalez FJ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20814, USA.
Ross AC; Department of Nutritional Sciences, Pennsylvania State University, University Park, PA 16802, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 May 11; Vol. 24 (10). Date of Electronic Publication: 2023 May 11.
Typ publikacji:: Journal Article
MeSH Terms:: Hepatocyte Nuclear Factor 4*/genetics
Hepatocyte Nuclear Factor 4*/metabolism
Hepatocytes*/metabolism
Tretinoin*/pharmacology
Receptors, Retinoic Acid*/genetics
Animals ; Humans ; Mice ; Glucose ; Lipids ; Retinoic Acid Receptor alpha/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Retinoic Acid and Retinoid X Receptors.
Autorzy:: Schubert M; Laboratoire de Biologie du Développement de Villefranche-sur-Mer, Institut de la Mer de Villefranche, Sorbonne Université, CNRS, 181 Chemin du Lazaret, 06230 Villefranche-sur-Mer, France.
Germain P; Centre de Biologie Structurale, CNRS, INSERM, Univ Montpellier, 29 Rue de Navacelles, 34090 Montpellier, France.; Pokaż więcej
Źródło:: Cells [Cells] 2023 Mar 10; Vol. 12 (6). Date of Electronic Publication: 2023 Mar 10.
Typ publikacji:: Editorial; Research Support, Non-U.S. Gov't
MeSH Terms:: Tretinoin*/pharmacology
Receptors, Retinoic Acid*
Humans ; Retinoid X Receptors

Raport

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: Targeting Cellular Retinoic Acid Binding Protein 1 with Retinoic Acid-like Compounds to Mitigate Motor Neuron Degeneration.
Autorzy:: Nhieu J; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Milbauer L; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Lerdall T; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Najjar F; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Wei CW; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.
Ishida R; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Ma Y; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Kagechika H; Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Wei LN; Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 04; Vol. 24 (5). Date of Electronic Publication: 2023 Mar 04.
Typ publikacji:: Journal Article
MeSH Terms:: Calcium-Calmodulin-Dependent Protein Kinase Type 2*/metabolism
Nerve Degeneration*
Receptors, Retinoic Acid*/metabolism
Tretinoin*/metabolism
Motor Neurons*/pathology
Animals ; Mice

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: A novel nuclear receptor subfamily enlightens the origin of heterodimerization.
Autorzy:: Beinsteiner B; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Markov GV; Sorbonne Université, CNRS, UMR 8227, Integrative Biology of Marine Models, (LBI2M, UMR8227), Station Biologique de Roscoff (SBR), 29680, Roscoff, France.
Bourguet M; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000, Strasbourg, France.; Infrastructure Nationale de Protéomique ProFI - FR2048 CNRS CEA, 67087, Strasbourg, France.
McEwen AG; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Erb S; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000, Strasbourg, France.; Infrastructure Nationale de Protéomique ProFI - FR2048 CNRS CEA, 67087, Strasbourg, France.
Patel AKM; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
El Khaloufi El Khaddar FZ; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Lecroisey C; Ecole Normale Supérieure de Lyon, Université de Lyon, Institut de Génomique Fonctionnelle de Lyon, UMR 5242 CNRS, Molecular Zoology Team, 46 allée d'Italie, 69364, Lyon, Cedex 07, France.
Holzer G; Ecole Normale Supérieure de Lyon, Université de Lyon, Institut de Génomique Fonctionnelle de Lyon, UMR 5242 CNRS, Molecular Zoology Team, 46 allée d'Italie, 69364, Lyon, Cedex 07, France.; Present address: Uniklinikum RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Nordrhein-Westfalen, Germany.
Essabri K; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Hazemann I; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Hamiche A; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Cianférani S; Laboratoire de Spectrométrie de Masse BioOrganique, Université de Strasbourg, CNRS, IPHC UMR 7178, 67000, Strasbourg, France.; Infrastructure Nationale de Protéomique ProFI - FR2048 CNRS CEA, 67087, Strasbourg, France.
Moras D; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France.; Université de Strasbourg, Illkirch, France.; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France.; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France.
Laudet V; Marine Eco-Evo-Devo Unit, Okinawa Institute of Science and Technology, 1919-1 Tancha, Onna-son, Okinawa, 904-0495, Japan. .; Marine Research Station, Institute of Cellular and Organismic Biology, Academia Sinica, 23-10, Dah-Uen Rd, Jiau Shi, I-Lan, 262, Taiwan. .
Billas IML; IGBMC (Institute of Genetics and of Molecular and Cellular Biology), Illkirch, France. .; Université de Strasbourg, Illkirch, France. .; Institut National de la Santé et de la Recherche Médicale (INSERM) U1258, Illkirch, France. .; Centre National de la Recherche Scientifique (CNRS) UMR 7104, Illkirch, France. .; Pokaż więcej
Źródło:: BMC biology [BMC Biol] 2022 Oct 05; Vol. 20 (1), pp. 217. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Receptors, Glucocorticoid*/genetics
Receptors, Retinoic Acid*/chemistry
Receptors, Retinoic Acid*/genetics
Receptors, Retinoic Acid*/metabolism
Animals ; DNA ; Dimerization ; Humans ; Ketosteroids ; Ligands ; Phylogeny ; Receptors, Cytoplasmic and Nuclear/genetics ; Retinoid X Receptors/chemistry ; Retinoid X Receptors/genetics ; Retinoid X Receptors/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Novel Vitamin D3 Hydroxymetabolites Require Involvement of the Vitamin D Receptor or Retinoic Acid-Related Orphan Receptors for Their Antifibrogenic Activities in Human Fibroblasts.
Autorzy:: Janjetovic Z; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Qayyum S; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Brigham's Women's Hospital, Harvard University, Boston, MA 02115, USA.
Reddy SB; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Podgorska E; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Scott SG; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Szpotan J; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Mobley AA; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Li W; College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Boda VK; College of Pharmacy, The University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Ravichandran S; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Tuckey RC; School of Molecular Science, The University of Western Australia, Perth 6009, Australia.
Jetten AM; Cell Biology Section, NIEHS, National Institutes of Health, Research Triangle Park, NC 27709, USA.
Slominski AT; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Cancer Chemoprevention Program, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; VA Medical Center, Birmingham, AL 35294, USA.; Pokaż więcej
Źródło:: Cells [Cells] 2024 Jan 26; Vol. 13 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:: Journal Article
MeSH Terms:: Cholecalciferol*/pharmacology
Receptors, Calcitriol*/metabolism
Humans ; Receptors, Retinoic Acid ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/genetics ; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism ; Fibroblasts/metabolism ; Collagen ; Tretinoin

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: A non-retinol retinoic acid receptor-γ (RAR-γ/NR1B3) selective agonist, tectorigenin, can effectively inhibit the ultraviolet A-induced skin damage.
Autorzy:: Dai X; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Jin J; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.
Jia Y; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Yang K; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.
Han J; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Zhang Z; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Ding X; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Yao C; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.
Sun T; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.
Zhu C; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.
Liu H; Cheermore Cosmetic Dermatology Laboratory, Shanghai, China.; State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy, Nankai University, Tianjin, China.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Oct; Vol. 179 (19), pp. 4722-4737. Date of Electronic Publication: 2022 Jul 20.
Typ publikacji:: Journal Article
MeSH Terms:: Dermatitis*/prevention & control
Proteomics*
Receptors, Retinoic Acid*/metabolism
Animals ; Inflammation ; Isoflavones ; Mice ; Molecular Docking Simulation ; Tretinoin/pharmacology ; Ultraviolet Rays

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Molluscan RXR Transcriptional Regulation by Retinoids in a Drosophila CNS Organ Culture System.
Autorzy:: de Hoog E; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Saba Echezarreta VE; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Turgambayeva A; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Foran G; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Megaly M; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Necakov A; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Spencer GE; Department of Biological Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.; Pokaż więcej
Źródło:: Cells [Cells] 2022 Aug 11; Vol. 11 (16). Date of Electronic Publication: 2022 Aug 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Drosophila*/metabolism
Receptors, Retinoic Acid*/metabolism
Animals ; Ligands ; Organ Culture Techniques ; Retinoid X Receptors/genetics ; Retinoids/metabolism ; Retinoids/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: A retinoic acid receptor β2 agonist protects against alcohol liver disease and modulates hepatic expression of canonical retinoid metabolism genes.
Autorzy:: Melis M; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Tang XH; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Attarwala N; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Chen Q; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Prishker C; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Qin L; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA.
Gross SS; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Gudas LJ; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.
Trasino SE; Department of Pharmacology, Weill Cornell Medicine, New York, New York, USA.; Nutrition Program, Hunter College, City University of New York, New York, New York, USA.; Pokaż więcej
Źródło:: BioFactors (Oxford, England) [Biofactors] 2022 Mar; Vol. 48 (2), pp. 469-480. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:: Journal Article
MeSH Terms:: Liver*
Receptors, Retinoic Acid*/agonists
Receptors, Retinoic Acid*/genetics
Receptors, Retinoic Acid*/metabolism
Lipid Metabolism ; Retinoids/genetics ; Retinoids/metabolism ; Retinoids/pharmacology ; Tretinoin/metabolism ; Tretinoin/pharmacology ; Vitamin A/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment.
Autorzy:: Wei CH; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Huang L; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Kreh B; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Liu X; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Tyutyunyk-Massey L; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Kawakami M; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Chen Z; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Shi M; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Kozlov S; Center for Advanced Preclinical Research, Frederick, MD, USA.
Chan KC; Protein Characterization Laboratory, Frederick, MD, USA.
Andresson T; Protein Characterization Laboratory, Frederick, MD, USA.
Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.; Laboratory of Integrative Cancer Immunology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Vuligonda V; Io Therapeutics, Inc., Spring, TX, USA.
Sanders ME; Io Therapeutics, Inc., Spring, TX, USA.
Horowitz A; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Moffitt Cancer Center, Tampa, FL, USA.
Peng W; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Dmitrovsky E; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA.
Liu X; Molecular Pharmacology Program, Frederick National Laboratory for Cancer Research, PO Box B, Frederick, MD, 21701, USA. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2023 Sep 09; Vol. 13 (1), pp. 14907. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms:: CD8-Positive T-Lymphocytes*
Lung Neoplasms*/drug therapy
Animals ; Mice ; Interleukin-13 ; Interleukin-5 ; Tumor Microenvironment ; Receptors, Retinoic Acid ; Tretinoin ; Carcinogenesis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: 1,5-Disubstituted Acylated 2-Amino-4,5-dihydroimidazoles as a New Class of Retinoic Acid Receptor-Related Orphan Receptor (ROR) Inhibitors.
Autorzy:: Ortiz MA; Donald P. Shiley BioScience Center, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, USA.
Piedrafita FJ; Donald P. Shiley BioScience Center, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, USA.
Nefzi A; Center for Translational Science, Florida International University, 11350 SW Village Parkway, Port Saint Lucie, FL 34987, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Apr 17; Vol. 23 (8). Date of Electronic Publication: 2022 Apr 17.
Typ publikacji:: Journal Article
MeSH Terms:: Arthritis, Rheumatoid*
Receptors, Retinoic Acid*
Humans ; Nuclear Receptor Subfamily 1, Group F, Member 3 ; Protein Isoforms ; Th17 Cells

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling.
Autorzy:: Yu S; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Wang L; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Che D; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Zhang M; Department of Biomedical Engineering, School of Engineering, Case Western Reserve University, Cleveland, OH, USA.
Li M; Biostatistics and Bioinformatics Core Facility, Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Division of Biostatistics of the Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angles, California, USA.
Naito M; Division of Molecular Target and Gene Therapy Products, National Institute of Health Sciences, Kanagawa, Japan.
Xin W; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.; Department of Pathology, University Hospitals Case Medical Center, Cleveland, OH, USA.
Zhou L; Department of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA. .; Department of Pathology, University Hospitals Case Medical Center, Cleveland, OH, USA. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Mar 08; Vol. 41 (1), pp. 88. Date of Electronic Publication: 2022 Mar 08.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Pancreatic Ductal*/drug therapy
Carcinoma, Pancreatic Ductal*/genetics
Carcinoma, Pancreatic Ductal*/metabolism
Pancreatic Neoplasms*/drug therapy
Pancreatic Neoplasms*/genetics
Pancreatic Neoplasms*/metabolism
Receptors, Retinoic Acid*/metabolism
Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Cholesterol ; Drug Resistance, Neoplasm/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Membrane Microdomains ; Neoplasm Recurrence, Local/genetics ; Proto-Oncogene Proteins c-akt/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics.
Autorzy:: López-Pérez AR; Laboratory of Zebrafish Development and Disease Models (ZDDM), GIGA-R, SART TILMAN, University of Liège, Avenue de l'Hôpital 1, B34, 4000, Liège, Belgium.; Umeå Centre for Molecular Medicine (UCMM), Umeå University, Umeå, Sweden.
Balwierz PJ; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Lenhard B; Institute of Clinical Sciences and MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, London, W12 0NN, UK.
Muller F; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Wardle FC; Randall Centre for Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.
Manfroid I; Laboratory of Zebrafish Development and Disease Models (ZDDM), GIGA-R, SART TILMAN, University of Liège, Avenue de l'Hôpital 1, B34, 4000, Liège, Belgium.
Voz ML; Laboratory of Zebrafish Development and Disease Models (ZDDM), GIGA-R, SART TILMAN, University of Liège, Avenue de l'Hôpital 1, B34, 4000, Liège, Belgium.
Peers B; Laboratory of Zebrafish Development and Disease Models (ZDDM), GIGA-R, SART TILMAN, University of Liège, Avenue de l'Hôpital 1, B34, 4000, Liège, Belgium. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Nov 22; Vol. 11 (1), pp. 22717. Date of Electronic Publication: 2021 Nov 22.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Genomics*
Transcriptome*
Pancreas/*drug effects
Receptors, Retinoic Acid/*agonists
Tretinoin/*pharmacology
Zebrafish/*genetics
Animals ; Animals, Genetically Modified ; Chromatin Assembly and Disassembly ; Chromatin Immunoprecipitation Sequencing ; GATA Transcription Factors/genetics ; GATA Transcription Factors/metabolism ; Gene Expression Regulation, Developmental ; Hepatocyte Nuclear Factor 1-beta/genetics ; Hepatocyte Nuclear Factor 1-beta/metabolism ; Homeodomain Proteins/genetics ; Homeodomain Proteins/metabolism ; Mice ; Pancreas/embryology ; Pancreas/metabolism ; RNA-Seq ; Receptors, Retinoic Acid/genetics ; Receptors, Retinoic Acid/metabolism ; Signal Transduction ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Zebrafish/embryology ; Zebrafish/metabolism ; Zebrafish Proteins/genetics ; Zebrafish Proteins/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Retinoic Acid Receptor β Loss in Hepatocytes Increases Steatosis and Elevates the Integrated Stress Response in Alcohol-Associated Liver Disease.
Autorzy:: Melis M; Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.
Trasino SE; Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.; Nutrition Program, Hunter College, City University of New York, New York, NY 10065, USA.
Tang XH; Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.
Rappa A; Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.
Zhang T; Genomics Resources Core Facility, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.
Qin L; Division of Anatomic Pathology, New York Presbyterian Hospital, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.
Gudas LJ; Department of Pharmacology, Weill Cornell Medical College of Cornell University, New York, NY 10065, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 27; Vol. 24 (15). Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Liver Diseases, Alcoholic*/metabolism
Fatty Liver*/metabolism
Mice ; Humans ; Animals ; Ethanol/toxicity ; Ethanol/metabolism ; Vitamin A/metabolism ; Mice, Knockout ; Hepatocytes/metabolism ; Liver/metabolism ; Receptors, Retinoic Acid/genetics ; Receptors, Retinoic Acid/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly.
Autorzy:: Kimmel BR; Department of Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA.
Mrksich M; Department of Biomedical Engineering, Department of Chemistry, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA.; Pokaż więcej
Źródło:: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2021 Dec 20; Vol. 27 (71), pp. 17843-17848. Date of Electronic Publication: 2021 Nov 17.
Typ publikacji:: Journal Article
MeSH Terms:: Enzyme Inhibitors*
Receptors, Retinoic Acid*
Humans ; Protein Domains

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: The Role of ATRA, Natural Ligand of Retinoic Acid Receptors, on EMT-Related Proteins in Breast Cancer: Minireview.
Autorzy:: Bobal P; Department of Chemical Drugs, Faculty of Pharmacy, Masaryk University, 612 00 Brno, Czech Republic.
Lastovickova M; Institute of Analytical Chemistry of the CAS, v. v. i., 602 00 Brno, Czech Republic.
Bobalova J; Institute of Analytical Chemistry of the CAS, v. v. i., 602 00 Brno, Czech Republic.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 12; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 12.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Epithelial-Mesenchymal Transition*
Breast Neoplasms/*metabolism
Neoplasm Proteins/*metabolism
Receptors, Retinoic Acid/*metabolism
Tretinoin/*metabolism
Animals ; Breast Neoplasms/mortality ; Breast Neoplasms/pathology ; Female ; Humans ; Neoplasm Metastasis ; Neoplasm Proteins/agonists ; Receptors, Retinoic Acid/agonists

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Crabp1 Modulates HPA Axis Homeostasis and Anxiety-like Behaviors by Altering FKBP5 Expression.
Autorzy:: Lin YL; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Wei CW; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Lerdall TA; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Nhieu J; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Wei LN; Department of Pharmacology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Nov 12; Vol. 22 (22). Date of Electronic Publication: 2021 Nov 12.
Typ publikacji:: Journal Article
MeSH Terms:: Anxiety/*physiopathology
Homeostasis/*physiology
Hypothalamo-Hypophyseal System/*metabolism
Pituitary-Adrenal System/*metabolism
Receptors, Retinoic Acid/*metabolism
Tacrolimus Binding Proteins/*metabolism
Animals ; Anxiety/genetics ; Cell Line, Tumor ; Dexamethasone/pharmacology ; Feedback, Physiological/drug effects ; Feedback, Physiological/physiology ; Gene Expression Regulation/drug effects ; Homeostasis/genetics ; Hypothalamus/metabolism ; Male ; Maze Learning/physiology ; Mice, Inbred C57BL ; Mice, Knockout ; Motor Activity/genetics ; Motor Activity/physiology ; Pituitary Gland/metabolism ; Receptors, Glucocorticoid/genetics ; Receptors, Glucocorticoid/metabolism ; Receptors, Retinoic Acid/genetics ; Tacrolimus Binding Proteins/genetics ; Mice

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: The RARγ Oncogene: An Achilles Heel for Some Cancers.
Autorzy:: Brown G; Institute of Clinical Sciences, School of Biomedical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B152TT, UK.
Petrie K; School of Medicine, Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland SR13SD, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 31; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Neoplastic Stem Cells/*metabolism
Receptors, Retinoic Acid/*genetics
Receptors, Retinoic Acid/*metabolism
Cell Division/physiology ; Humans ; Neoplasms/metabolism ; Neoplasms/therapy ; Neoplastic Stem Cells/physiology ; Oncogenes/genetics ; Receptors, Retinoic Acid/antagonists & inhibitors ; Receptors, Retinoic Acid/physiology ; Retinoic Acid Receptor gamma

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection.
Autorzy:: Baidya S; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Nishimoto Y; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Sato S; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Shimada Y; Asai Germanium Research Institute Co., Ltd. Suzuranoka, Hakodate 042-0958, Japan.
Sakurai N; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Nonaka H; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Noguchi K; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Kido M; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Tadano S; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Ishikawa K; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.
Li K; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Okubo A; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Yamada T; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.
Orba Y; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Sasaki M; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Sawa H; Division of Molecular Pathobiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.; Global Virus Network, Baltimore, MD 21201, USA.
Miyamoto H; Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Takada A; International Collaboration Unit, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.; Division of Global Epidemiology, International Institute for Zoonosis Control, Hokkaido University, Sapporo 001-0020, Japan.
Nakamura T; Asai Germanium Research Institute Co., Ltd. Suzuranoka, Hakodate 042-0958, Japan.
Takaoka A; Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.; Molecular Medical Biochemistry Unit, Biological Chemistry and Engineering Course, Graduate School of Chemical Sciences and Engineering, Hokkaido University, Sapporo 060-0815, Japan.; Pokaż więcej
Źródło:: Viruses [Viruses] 2021 Aug 24; Vol. 13 (9). Date of Electronic Publication: 2021 Aug 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antiviral Agents/*pharmacology
Immunity, Innate/*drug effects
Influenza A virus/*physiology
Organometallic Compounds/*pharmacology
Receptors, Retinoic Acid/*genetics
Viral Nonstructural Proteins/*genetics
Virus Replication/*drug effects
A549 Cells ; Animals ; Antiviral Agents/metabolism ; Antiviral Agents/therapeutic use ; Host-Pathogen Interactions/drug effects ; Humans ; Influenza A virus/immunology ; Influenza A virus/pathogenicity ; Interferon Type I/immunology ; Interferon Type I/metabolism ; Mice ; Organometallic Compounds/metabolism ; Organometallic Compounds/therapeutic use ; Orthomyxoviridae Infections/drug therapy ; Orthomyxoviridae Infections/immunology ; Orthomyxoviridae Infections/virology ; RAW 264.7 Cells ; RNA, Viral/genetics ; RNA, Viral/metabolism ; Receptors, Retinoic Acid/immunology ; Viral Nonstructural Proteins/metabolism ; Virus Replication/genetics

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Receptors, Retinoic Acid"" wg kryterium: Temat

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język