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Wyświetlanie 61-80 z 820
Tytuł:
Blocking transferrin receptor inhibits the growth of lung adenocarcinoma cells in vitro.
Autorzy:
Wu Y; Department of Thoracic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Xu J; Department of Thoracic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Chen J; College of Medicine, Zhejiang University, Hangzhou, China.
Zou M; College of Medicine, Zhejiang University, Hangzhou, China.
Rusidanmu A; Department of Thoracic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
Yang R; Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.
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Źródło:
Thoracic cancer [Thorac Cancer] 2018 Feb; Vol. 9 (2), pp. 253-261. Date of Electronic Publication: 2017 Dec 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adenocarcinoma/*drug therapy
Adenocarcinoma/*genetics
Lung Neoplasms/*drug therapy
Lung Neoplasms/*genetics
Proto-Oncogene Proteins p21(ras)/*genetics
Receptors, Transferrin/*antagonists & inhibitors
Adenocarcinoma/pathology ; Adenocarcinoma of Lung ; Antibodies, Monoclonal/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Lung Neoplasms/pathology ; Microarray Analysis ; RNA Interference ; Receptors, Transferrin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transferrin receptor 1 is a reticulocyte-specific receptor for Plasmodium vivax .
Autorzy:
Gruszczyk J; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.
Kanjee U; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Chan LJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Menant S; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.
Malleret B; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, 117597 Singapore.; Singapore Immunology Network, A*STAR, 138648 Singapore.
Lim NTY; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.
Schmidt CQ; Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm University, Germany.
Mok YF; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Lin KM; Cambridge Institute for Medical Research, Cambridge CB2 OXY, UK.
Pearson RD; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Oxford, UK.
Rangel G; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Smith BJ; La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Call MJ; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Weekes MP; Cambridge Institute for Medical Research, Cambridge CB2 OXY, UK.
Griffin MDW; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Murphy JM; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
Abraham J; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
Sriprawat K; Shoklo Malaria Research Unit, Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.
Menezes MJ; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Ferreira MU; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
Russell B; Department of Microbiology and Immunology, University of Otago, Dunedin 9054, New Zealand.
Renia L; Singapore Immunology Network, A*STAR, 138648 Singapore.
Duraisingh MT; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
Tham WH; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria 3010, Australia.
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Źródło:
Science (New York, N.Y.) [Science] 2018 Jan 05; Vol. 359 (6371), pp. 48-55.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD/*metabolism
Malaria, Vivax/*metabolism
Malaria, Vivax/*parasitology
Membrane Proteins/*chemistry
Plasmodium vivax/*pathogenicity
Protozoan Proteins/*chemistry
Receptors, Transferrin/*metabolism
Reticulocytes/*parasitology
Antigens, CD/genetics ; Crystallography, X-Ray ; Gene Knockdown Techniques ; Host-Parasite Interactions ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Membrane Proteins/ultrastructure ; Plasmodium vivax/metabolism ; Protein Domains ; Protozoan Proteins/genetics ; Protozoan Proteins/metabolism ; Protozoan Proteins/ultrastructure ; Receptors, Transferrin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Potent but transient immunosuppression of T-cells is a general feature of CD71 erythroid cells.
Autorzy:
Grzywa TM; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.; Doctoral School of the Medical University of Warsaw, Warsaw, Poland.; Laboratory of Experimental Medicine, Medical University of Warsaw, Warsaw, Poland.
Sosnowska A; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.; Postgraduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland.
Rydzynska Z; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.; Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland.
Lazniewski M; Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, Warsaw, Poland.; Centre for Advanced Materials and Technologies, Warsaw University of Technology, Warsaw, Poland.
Plewczynski D; Laboratory of Functional and Structural Genomics, Centre of New Technologies, University of Warsaw, Warsaw, Poland.; Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland.
Klicka K; Doctoral School of the Medical University of Warsaw, Warsaw, Poland.; Department of Methodology, Medical University of Warsaw, Warsaw, Poland.
Malecka-Gieldowska M; Department of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland.
Rodziewicz-Lurzynska A; Central Laboratory, University Clinical Center of Medical University of Warsaw, Warsaw, Poland.
Ciepiela O; Department of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland.
Justyniarska M; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
Pomper P; OncoArendi Therapeutics, Warsaw, Poland.
Grzybowski MM; OncoArendi Therapeutics, Warsaw, Poland.
Blaszczyk R; OncoArendi Therapeutics, Warsaw, Poland.
Wegrzynowicz M; Laboratory of Molecular Basis of Neurodegeneration, Mossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland.
Tomaszewska A; Department of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Basak G; Department of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland.
Golab J; Department of Immunology, Medical University of Warsaw, Warsaw, Poland. .; Centre of Preclinical Research, Medical University of Warsaw, Warsaw, Poland. .
Nowis D; Department of Immunology, Medical University of Warsaw, Warsaw, Poland. .; Laboratory of Experimental Medicine, Medical University of Warsaw, Warsaw, Poland. .
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Źródło:
Communications biology [Commun Biol] 2021 Dec 10; Vol. 4 (1), pp. 1384. Date of Electronic Publication: 2021 Dec 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Immune Tolerance*
Erythroid Cells/*immunology
T-Lymphocytes/*immunology
Adult ; Animals ; Antigens, CD/metabolism ; Cell Line ; Humans ; Mice ; Mice, Inbred C57BL ; Receptors, Transferrin/metabolism ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Brain-targeting delivery of MMB4 DMS using carrier-free nanomedicine CRT-MMB4@MDZ.
Autorzy:
Du Y; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Gao J; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zhang H; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Meng X; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Qiu D; Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Gao X; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
Zheng A; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.
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Źródło:
Drug delivery [Drug Deliv] 2021 Dec; Vol. 28 (1), pp. 1822-1835.
Typ publikacji:
Journal Article
MeSH Terms:
Antidotes/*pharmacokinetics
Brain/*metabolism
Midazolam/*pharmacokinetics
Nanoparticles/*chemistry
Oximes/*chemistry
Animals ; Antidotes/administration & dosage ; Cell Line ; Dose-Response Relationship, Drug ; Drug Liberation ; Drug Stability ; Male ; Mice ; Mice, Inbred C57BL ; Midazolam/administration & dosage ; Particle Size ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Receptors, Transferrin/metabolism ; Surface Properties
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Arsenite exposure inhibits the erythroid differentiation of human hematopoietic progenitor CD34  cells and causes decreased levels of hemoglobin.
Autorzy:
Wan G; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Medina S; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.; Department of Biology, New Mexico Highlands University, Las Vegas, NM, 87701, USA.
Zhang H; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Pan R; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Zhou X; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Bolt AM; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Luo L; Division of Epidemiology, Biostatistics and Preventive Medicine at the University of New Mexico, Albuquerque, NM, 87131, USA.
Burchiel SW; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA.
Liu KJ; Department of Pharmaceutical Sciences, The University of New Mexico College of Pharmacy, Albuquerque, NM, 87131, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 11; Vol. 11 (1), pp. 22121. Date of Electronic Publication: 2021 Nov 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antigens, CD34/*metabolism
Arsenites/*adverse effects
Cell Differentiation/*drug effects
Erythroid Precursor Cells/*drug effects
Hematopoietic Stem Cells/*drug effects
Hemoglobins/*metabolism
Anemia/chemically induced ; Anemia/metabolism ; Antigens, CD/metabolism ; Cells, Cultured ; Erythroblasts/drug effects ; Erythroblasts/metabolism ; Erythroid Precursor Cells/metabolism ; Erythropoiesis/drug effects ; Glycophorins/metabolism ; Hematopoietic Stem Cells/metabolism ; Humans ; Receptors, Transferrin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes.
Autorzy:
Tiengwe C; Department of Microbiology & Immunology, School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, United States of America.
Bush PJ; South Campus Instrument Center, School of Dental Medicine, University at Buffalo (SUNY), Buffalo, New York, United States of America.
Bangs JD; Department of Microbiology & Immunology, School of Medicine and Biomedical Sciences, University at Buffalo (SUNY), Buffalo, New York, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2017 May 01; Vol. 13 (5), pp. e1006366. Date of Electronic Publication: 2017 May 01 (Print Publication: 2017).
Typ publikacji:
Journal Article
MeSH Terms:
Protein Transport*
Glycosylphosphatidylinositols/*metabolism
Receptors, Transferrin/*metabolism
Trypanosoma brucei brucei/*physiology
Trypanosomiasis, African/*parasitology
Variant Surface Glycoproteins, Trypanosoma/*metabolism
Amino Acid Sequence ; Animals ; Base Sequence ; Cell Line ; Cell Membrane/metabolism ; Dimerization ; Glycosylphosphatidylinositols/genetics ; Humans ; Lysosomes/metabolism ; RNA Interference ; Receptors, Transferrin/genetics ; Sequence Alignment ; Trypanosoma brucei brucei/genetics ; Trypanosoma brucei brucei/ultrastructure ; Up-Regulation ; Variant Surface Glycoproteins, Trypanosoma/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Flow cytometric expression of CD71, CD81, CD44 and CD39 in B cell lymphoma.
Autorzy:
Espasa A; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.
Tapia G; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.; Department of Pathology, Hospital Germans Trias i Pujol, Badalona, Spain.
Vergara S; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.
Raya M; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.
Juncà J; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.
Sorigue M; Hematology Laboratory,ICO-Hospital Germans Trias i Pujol, LUMN, IJC-Functional Cytomics unit, UAB, Badalona, Spain.
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Źródło:
Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2021 Sep; Vol. 81 (5), pp. 413-417. Date of Electronic Publication: 2021 May 31.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD/*analysis
Apyrase/*analysis
Flow Cytometry/*methods
Hyaluronan Receptors/*analysis
Lymphoma, B-Cell/*immunology
Receptors, Transferrin/*analysis
Tetraspanin 28/*analysis
Female ; Humans ; Male
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX.
Autorzy:
Zhang N; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Bing T; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Shen L; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Feng L; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Liu X; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.
Shangguan D; Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.; School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China.; School of Molecular Medicine, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou 310024, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 19; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Aptamers, Nucleotide/*metabolism
Neoplasms/*metabolism
Receptors, Transferrin/*metabolism
SELEX Aptamer Technique/*methods
Aptamers, Nucleotide/chemistry ; Humans ; Ligands ; Neoplasms/pathology ; Transcytosis ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Prion Protein on Human Leukocytes Is Reduced in Iron Deficiency - Possible Implications for Age-related Macular Degeneration?
Autorzy:
Lindner E; Department of Ophthalmology, Medical University Graz, Graz, Austria.
Woltsche N; Department of Ophthalmology, Medical University Graz, Graz, Austria.
Merle D; Department of Ophthalmology, Medical University Graz, Graz, Austria.
Steinwender G; Department of Ophthalmology, Medical University Graz, Graz, Austria.
Strohmaier H; Core Facility Imaging, Centre of Medical Research Graz, Graz, Austria.
Nairz M; Department of General Internal Medicine, Medical University Innsbruck, Innsbruck, Austria.
Ivastinovic D; Department of Ophthalmology, Medical University Graz, Graz, Austria.
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Źródło:
Current eye research [Curr Eye Res] 2021 Aug; Vol. 46 (8), pp. 1178-1183. Date of Electronic Publication: 2020 Dec 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Iron Deficiencies/*metabolism
Leukocytes/*metabolism
Macular Degeneration/*metabolism
PrPC Proteins/*metabolism
Aged ; Aged, 80 and over ; CD4-Positive T-Lymphocytes/metabolism ; Enzyme-Linked Immunosorbent Assay ; Female ; Ferritins/blood ; Flow Cytometry ; Humans ; Immunophenotyping ; Intraocular Pressure/physiology ; Lipopolysaccharide Receptors/metabolism ; Male ; Middle Aged ; Monocytes/metabolism ; Receptors, Transferrin/blood ; Slit Lamp Microscopy ; Tonometry, Ocular ; Visual Acuity/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Primary Human Cardiomyocytes and Cardiofibroblasts Treated with Sera from Myocarditis Patients Exhibit an Increased Iron Demand and Complex Changes in the Gene Expression.
Autorzy:
Kobak KA; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Franczuk P; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.
Schubert J; Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Dzięgała M; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Kasztura M; Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Tkaczyszyn M; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.
Drozd M; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.
Kosiorek A; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.; Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Kiczak L; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Bania J; Department of Food Hygiene and Consumer Health Protection, Wroclaw University of Environmental and Life Sciences, 50-375 Wroclaw, Poland.
Ponikowski P; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.; Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Jankowska EA; Laboratory for Applied Research on Cardiovascular System, Department of Heart Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.; Centre for Heart Diseases, University Hospital, 50-556 Wroclaw, Poland.
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Źródło:
Cells [Cells] 2021 Apr 06; Vol. 10 (4). Date of Electronic Publication: 2021 Apr 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation*
Fibroblasts/*metabolism
Iron/*metabolism
Myocarditis/*blood
Myocytes, Cardiac/*metabolism
Acute Disease ; Adult ; Case-Control Studies ; Cell Survival ; Cells, Cultured ; Down-Regulation/genetics ; Female ; Ferritins/blood ; Gene Expression Profiling ; Humans ; Inflammation/genetics ; Inflammation/pathology ; Male ; Middle Aged ; Myocarditis/genetics ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism ; Treatment Outcome ; Up-Regulation/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The blood-brain barrier studied in vitro across species.
Autorzy:
Thomsen MS; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
Humle N; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
Hede E; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
Moos T; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
Burkhart A; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
Thomsen LB; Department of Health Science and Technology, Neurobiology Research and Drug Delivery, Aalborg University, Aalborg, Denmark.
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Źródło:
PloS one [PLoS One] 2021 Mar 12; Vol. 16 (3), pp. e0236770. Date of Electronic Publication: 2021 Mar 12 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood-Brain Barrier/*metabolism
ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Animals ; Astrocytes/cytology ; Astrocytes/metabolism ; Cell Culture Techniques ; Cell Size ; Cells, Cultured ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; Mice ; Models, Biological ; Permeability ; Rats ; Receptors, Transferrin/genetics ; Receptors, Transferrin/metabolism ; Swine ; Tight Junction Proteins/genetics ; Tight Junction Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Altered Erythropoiesis in Mouse Models of Type 3 Hemochromatosis.
Autorzy:
Pellegrino RM; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
Riondato F; Department of Veterinary Sciences, University of Torino, Grugliasco, Torino, Italy.
Ferbo L; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
Boero M; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
Palmieri A; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
Osella L; Department of Veterinary Sciences, University of Torino, Grugliasco, Torino, Italy.
Pollicino P; Department of Veterinary Sciences, University of Torino, Grugliasco, Torino, Italy.
Miniscalco B; Department of Veterinary Sciences, University of Torino, Grugliasco, Torino, Italy.
Saglio G; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
Roetto A; Department of Clinical and Biological Sciences, AOU San Luigi Gonzaga, University of Torino, Orbassano, Torino, Italy.
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Źródło:
BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 2408941. Date of Electronic Publication: 2017 May 02.
Typ publikacji:
Journal Article
MeSH Terms:
Hemochromatosis/*genetics
Iron/*metabolism
Protein Isoforms/*genetics
Receptors, Transferrin/*deficiency
Animals ; Disease Models, Animal ; Erythropoiesis/genetics ; Hemochromatosis/pathology ; Liver/metabolism ; Liver/pathology ; Mice ; Mice, Knockout ; Mononuclear Phagocyte System/metabolism ; Mononuclear Phagocyte System/pathology ; Receptors, Transferrin/genetics ; Spleen/metabolism ; Spleen/pathology
SCR Disease Name:
Hemochromatosis, type 3
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells.
Autorzy:
Bailey DK; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, United States of America.
Clark W; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, United States of America.
Kosman DJ; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Jul 26; Vol. 16 (7), pp. e0254794. Date of Electronic Publication: 2021 Jul 26 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain/*drug effects
Iron/*adverse effects
Iron Chelating Agents/*pharmacology
Quinazolinones/*pharmacology
Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Animals ; Antigens, CD/genetics ; Biological Transport/drug effects ; Blood-Brain Barrier/drug effects ; Brain/blood supply ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Ceruloplasmin/genetics ; Endothelial Cells/drug effects ; Ferritins/genetics ; Humans ; Iron/metabolism ; Membrane Proteins/genetics ; Microcirculation/drug effects ; Parkinson Disease/drug therapy ; Parkinson Disease/metabolism ; Parkinson Disease/pathology ; Receptors, Transferrin/genetics ; Transferrin/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The immunoregulatory function of peripheral blood CD71 erythroid cells in systemic-onset juvenile idiopathic arthritis.
Autorzy:
Kanemasa H; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Ishimura M; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. .
Eguchi K; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Tanaka T; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Nanishi E; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Shiraishi A; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Goto M; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Motomura Y; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Ohga S; Departments of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
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Źródło:
Scientific reports [Sci Rep] 2021 Jul 13; Vol. 11 (1), pp. 14396. Date of Electronic Publication: 2021 Jul 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Juvenile*
Antigens, CD ; C-Reactive Protein/metabolism ; Child ; Cytokines/metabolism ; Humans ; Infant, Newborn ; Leukocytes, Mononuclear ; Receptors, Transferrin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Bioengineered Ferritin Nanocarriers for Cancer Therapy.
Autorzy:
Sun X; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Hong Y; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Gong Y; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Zheng S; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
Xie D; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou 310014, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 29; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 29.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antigens, CD/*metabolism
Bioengineering/*methods
Ferritins/*metabolism
Neoplasms/*metabolism
Receptors, Transferrin/*metabolism
Animals ; Drug Carriers ; Drug Compounding ; Drug Delivery Systems ; Ferritins/genetics ; Humans ; Hydrogen-Ion Concentration ; Nanoparticles ; Neoplasms/drug therapy
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Novel aspects of iron homeostasis in pathogenic bloodstream form Trypanosoma brucei.
Autorzy:
Gilabert Carbajo C; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London, United Kingdom.
Cornell LJ; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London, United Kingdom.
Madbouly Y; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London, United Kingdom.
Lai Z; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London, United Kingdom.
Yates PA; Department of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, Oregon, United States of America.
Tinti M; Wellcome Trust Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, United Kingdom.
Tiengwe C; Department of Life Sciences, Sir Ernst Chain Building, Imperial College London, London, United Kingdom.
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Źródło:
PLoS pathogens [PLoS Pathog] 2021 Jun 23; Vol. 17 (6), pp. e1009696. Date of Electronic Publication: 2021 Jun 23 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Adaptation, Physiological/*physiology
Iron/*metabolism
Protozoan Proteins/*metabolism
Trypanosoma brucei brucei/*metabolism
Cells, Cultured ; Homeostasis/physiology ; RNA-Binding Proteins/metabolism ; Receptors, Transferrin/metabolism ; Transcriptome ; Trypanosomiasis, African/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Integrin α 2 β 1 -targeting ferritin nanocarrier traverses the blood-brain barrier for effective glioma chemotherapy.
Autorzy:
Huang CW; Center for Advanced Molecular Imaging and Translation (CAMIT), Department of Medical Research, Chang Gung Memorial Hospital, Linkou, Taiwan.
Chuang CP; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, AC2-414, No.1, Sec. 4, Roosevelt Rd., Taipei, 106319, Taiwan.
Chen YJ; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, AC2-414, No.1, Sec. 4, Roosevelt Rd., Taipei, 106319, Taiwan.
Wang HY; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, AC2-414, No.1, Sec. 4, Roosevelt Rd., Taipei, 106319, Taiwan.
Lin JJ; Center for Advanced Molecular Imaging and Translation (CAMIT), Department of Medical Research, Chang Gung Memorial Hospital, Linkou, Taiwan.
Huang CY; Department of Neurosurgery, Chang Gung Memorial Hospital, Linkou, Taiwan.
Wei KC; Department of Neurosurgery, Chang Gung Memorial Hospital, Linkou, Taiwan.; Department of Neurosurgery, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan.; School of Medicine, Chang Gung University, Taoyuan, Taiwan.
Huang FT; Department of Biochemical Science and Technology, College of Life Science, National Taiwan University, AC2-414, No.1, Sec. 4, Roosevelt Rd., Taipei, 106319, Taiwan. .
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Jun 13; Vol. 19 (1), pp. 180. Date of Electronic Publication: 2021 Jun 13.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier/*drug effects
Blood-Brain Barrier/*metabolism
Drug Carriers/*chemistry
Ferritins/*metabolism
Glioma/*drug therapy
Integrin alpha2beta1/*metabolism
Integrin alpha2beta1/*therapeutic use
Animals ; Brain Neoplasms/drug therapy ; Cell Line, Tumor ; Doxorubicin ; Drug Delivery Systems/methods ; Endothelial Cells/metabolism ; Ferritins/chemistry ; Humans ; Male ; Mice ; Mice, Nude ; Nanoparticles/therapeutic use ; Receptors, Transferrin ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Self-assembling ferritin-dendrimer nanoparticles for targeted delivery of nucleic acids to myeloid leukemia cells.
Autorzy:
Palombarini F; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Masciarelli S; Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology and Medical Embryology, Sapienza University of Rome, Laboratory Affiliated To Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Via A. Scarpa, 14-16, 00161, Rome, Italy.; Histology and Embryology Section, Department of Life Science and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, 00168, Roma, Italy.
Incocciati A; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Liccardo F; Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology and Medical Embryology, Sapienza University of Rome, Laboratory Affiliated To Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Via A. Scarpa, 14-16, 00161, Rome, Italy.
Di Fabio E; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Iazzetti A; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Fabrizi G; Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.
Fazi F; Department of Anatomical, Histological, Forensic & Orthopaedic Sciences, Section of Histology and Medical Embryology, Sapienza University of Rome, Laboratory Affiliated To Istituto Pasteur Italia-Fondazione Cenci Bolognetti, Via A. Scarpa, 14-16, 00161, Rome, Italy. .
Macone A; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. .
Bonamore A; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. .
Boffi A; Department of Biochemical Sciences 'Alessandro Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.; Center for Life Nano , Istituto Italiano Di Tecnologia, V.le Regina Elena 291, 00161, Rome, Italy.
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Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2021 Jun 09; Vol. 19 (1), pp. 172. Date of Electronic Publication: 2021 Jun 09.
Typ publikacji:
Journal Article
MeSH Terms:
Dendrimers/*chemistry
Drug Delivery Systems/*methods
Ferritins/*chemistry
Leukemia, Myeloid/*drug therapy
Nanoparticles/*chemistry
Nucleic Acids/*chemistry
Antigens, CD ; Archaeoglobus fulgidus/genetics ; Archaeoglobus fulgidus/metabolism ; Cell Line, Tumor ; Ferritins/genetics ; Humans ; MicroRNAs/chemistry ; MicroRNAs/pharmacology ; Receptors, Transferrin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Comparison of polypeptides that bind the transferrin receptor for targeting gold nanocarriers.
Autorzy:
McQuaid C; Department of Life Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Halsey A; Department of Life Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Dubois M; Department of Life Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Romero I; Department of Life Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Male D; Department of Life Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
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Źródło:
PloS one [PLoS One] 2021 Jun 04; Vol. 16 (6), pp. e0252341. Date of Electronic Publication: 2021 Jun 04 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Carriers/*metabolism
Gold/*metabolism
Metal Nanoparticles/*administration & dosage
Peptides/*metabolism
Receptors, Transferrin/*metabolism
Animals ; Biological Transport/physiology ; Blood-Brain Barrier/metabolism ; Brain/metabolism ; Cell Line ; Drug Delivery Systems/methods ; Endocytosis/physiology ; Endothelial Cells/metabolism ; Endothelium, Vascular/metabolism ; Humans ; Mice ; Transferrin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes.
Autorzy:
Kim BE; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Choi B; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Park WR; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Kim YJ; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Kim IY; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
Jung YS; School of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.
Kim YH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Lee CH; Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon 34141, Korea.
Choi HS; School of Biological Sciences and Technology, Chonnam National University, Gwangju 61186, Korea.
Kim DK; Department of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju 61186, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Jun 02; Vol. 22 (11). Date of Electronic Publication: 2021 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Liver/*drug effects
Liver Diseases, Alcoholic/*genetics
Receptor, Cannabinoid, CB1/*genetics
Receptors, Estrogen/*genetics
Receptors, Transferrin/*genetics
Alcohols/pharmacology ; Animals ; Arachidonic Acids/pharmacology ; Endocannabinoids/pharmacology ; Gene Expression Regulation/drug effects ; Glycerides/pharmacology ; Hep G2 Cells ; Hepatocytes/drug effects ; Humans ; Iron/metabolism ; Liver/metabolism ; Liver/pathology ; Liver Diseases, Alcoholic/metabolism ; Liver Diseases, Alcoholic/pathology ; Mice ; Promoter Regions, Genetic ; Receptor, Cannabinoid, CB1/agonists ; Sequence Deletion/genetics ; Transferrin/genetics ; Transferrin/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 61-80 z 820

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