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Wyszukujesz frazę ""Receptors, Urokinase Plasminogen Activator"" wg kryterium: Temat


Tytuł :
Soluble urokinase plasminogen activator receptor and lactate as prognostic biomarkers in patients presenting with non-specific chief complaints in the pre-hospital setting - the PRIUS-study.
Autorzy :
Ivic R; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden. .; Academic Emergency Medical Service, Region Stockholm, Stockholm, Sweden. .
Nurmi J; Emergency Medicine, Helsinki University and Department of Emergency Medicine and Services, Helsinki University Hospital, Helsinki, Finland.
Kurland L; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department for Medical Sciences, Örebro University, Örebro, Sweden.
Vicente V; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Lindström V; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, division of nursing, Stockholm, Sweden.; Samariten Ambulance Stockholm, Stockholm, Sweden.
Djärv T; Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Kaartinen J; Emergency Medicine, Helsinki University and Department of Emergency Medicine and Services, Helsinki University Hospital, Helsinki, Finland.
Castrén M; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Emergency Medicine, Helsinki University and Department of Emergency Medicine and Services, Helsinki University Hospital, Helsinki, Finland.
Bohm K; Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Department of Emergency Medicine, Södersjukhuset, Stockholm, Sweden.
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Źródło :
Scandinavian journal of trauma, resuscitation and emergency medicine [Scand J Trauma Resusc Emerg Med] 2021 Aug 12; Vol. 29 (1), pp. 116. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Lactic Acid*
Receptors, Urokinase Plasminogen Activator*
Biomarkers ; Hospitals ; Humans ; Prognosis ; Prospective Studies ; Risk Assessment
Czasopismo naukowe
Tytuł :
The Urokinase Receptor: A Multifunctional Receptor in Cancer Cell Biology. Therapeutic Implications.
Autorzy :
Li Santi A; Department of Chemistry and Biology, University of Salerno, Fisciano, 84084 Salerno, Italy.
Napolitano F; Department of Translational Medical Sciences, 'Federico II' University, 80135 Naples, Italy.
Montuori N; Department of Translational Medical Sciences, 'Federico II' University, 80135 Naples, Italy.
Ragno P; Department of Chemistry and Biology, University of Salerno, Fisciano, 84084 Salerno, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Apr 16; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 16.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Biomarkers, Tumor/*metabolism
Neoplasms/*metabolism
Receptors, Urokinase Plasminogen Activator/*metabolism
Animals ; Biomarkers, Tumor/genetics ; Humans ; Neoplasms/diagnosis ; Neoplasms/genetics ; Neoplasms/therapy ; Receptors, Urokinase Plasminogen Activator/chemistry ; Receptors, Urokinase Plasminogen Activator/genetics
Czasopismo naukowe
Tytuł :
Linking stressful life events and chronic inflammation using suPAR (soluble urokinase plasminogen activator receptor).
Autorzy :
Bourassa KJ; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, United Kingdom; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom.
Rasmussen LJH; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom; Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Hvidovre, Denmark.
Danese A; Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, & Neuroscience, King's College London, London, United Kingdom; Department of Child and Adolescent Psychiatry, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom; National and Specialist Child and Adolescent Mental Health Services Trauma, Anxiety, and Depression Clinic, South London and Maudsley National Health Service Foundation Trust, London, United Kingdom.
Eugen-Olsen J; Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Hvidovre, Denmark.
Harrington H; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom.
Houts R; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom.
Poulton R; Department of Psychology, University of Otago, Otago, New Zealand.
Ramrakha S; Department of Psychology, University of Otago, Otago, New Zealand.
Sugden K; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom.
Williams B; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom.
Moffitt TE; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, United Kingdom; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United Kingdom; Center for Genomic and Computational Biology, Duke University, Durham, NC, United Kingdom.
Caspi A; Center for the Study of Aging and Human Development, Duke University Medical Center, Durham, NC, United Kingdom; Department of Psychology & Neuroscience, Duke University, Durham, NC, United Kingdom; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United Kingdom; Center for Genomic and Computational Biology, Duke University, Durham, NC, United Kingdom.
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Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2021 Oct; Vol. 97, pp. 79-88. Date of Electronic Publication: 2021 Jul 02.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
C-Reactive Protein*/analysis
Receptors, Urokinase Plasminogen Activator*
Adult ; Biomarkers ; Humans ; Inflammation ; Longitudinal Studies ; Middle Aged
Czasopismo naukowe
Tytuł :
uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells.
Autorzy :
Biagioni A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Laurenzana A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Menicacci B; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Peppicelli S; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Andreucci E; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Bianchini F; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Guasti D; Department of Experimental and Clinical Medicine, University of Florence, Viale Pieraccini 6, 50139, Florence, Italy.
Paoli P; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Serratì S; Nanotecnology Laboratory, National Cancer Research Centre, IRCCS 'Giovanni Paolo II', Viale Orazio Flacco, 65, 70124, Bari, Italy.
Mocali A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Calorini L; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Del Rosso M; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Fibbi G; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy.
Chillà A; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy. .
Margheri F; Department of Experimental and Clinical Biomedical Sciences, Section of Experimental Pathology and Oncology, University of Florence, Viale G.B. Morgagni, 50, 50134, Florence, Italy. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Mar; Vol. 78 (6), pp. 3057-3072. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*
Antigens, CD/*metabolism
Cadherins/*metabolism
Exosomes/*metabolism
Receptors, Urokinase Plasminogen Activator/*metabolism
Animals ; Antigens, CD/genetics ; Cadherins/genetics ; Cell Line ; Endothelial Cells/cytology ; Endothelial Cells/metabolism ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Gefitinib/pharmacology ; Gene Editing ; Humans ; Melanoma/metabolism ; Melanoma/pathology ; Mice ; Mice, SCID ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Neovascularization, Physiologic ; Phosphorylation/drug effects ; RNA Interference ; RNA, Small Interfering ; Receptors, Urokinase Plasminogen Activator/antagonists & inhibitors ; Receptors, Urokinase Plasminogen Activator/genetics
Czasopismo naukowe
Tytuł :
Elevated levels of soluble urokinase plasminogen activator receptor as a low-grade inflammation marker in schizophrenia: A case-control study.
Autorzy :
Bigseth TT; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway. Electronic address: .
Fredriksen M; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway.
Egeland J; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway; Department of Psychology, University of Oslo, P.O box 1094, Blindern, 0317 Oslo, Norway.
Andersen E; Faculty of Humanities, Sports and Educational Science, University College of South-Eastern Norway, Post office box 235, 3603 Kongsberg, Norway.
Andreassen OA; NORMENT, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Psychosis Research Unit/TOP, Ullevaal Hospital, Building 49, P.O Box 4956 Nydalen, 0424 Oslo, Norway.
Bang-Kittilsen G; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway.
Falk RS; Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, Pb 4950 Nydalen, 0424 Oslo, Norway.
Holmen TL; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway.
Martinsen EW; Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, P.O Box 1072, Blindern, 0316 Oslo, Norway.
Mordal J; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway.
Nielsen J; Mental Health Centre Glostrup, Copenhagen University Hospital, Kristineberg 3, 2100 Copenhagen O, Denmark.
Steen NE; NORMENT, Division of Mental Health and Addiction, Oslo University Hospital & Institute of Clinical Medicine, University of Oslo, Psychosis Research Unit/TOP, Ullevaal Hospital, Building 49, P.O Box 4956 Nydalen, 0424 Oslo, Norway.
Ueland T; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Postboks 4950 Nydalen, 0424 Oslo, Norway; Institute of Clinical Medicine, University of Oslo Faculty of Health Sciences, P.O box 1171, Blindern, 0318 Oslo, Norway; K.G. Jebsen TREC, University of Tromso, 9037 Tromso, Norway.
Vang T; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway; Mental Health Centre Glostrup, Copenhagen University Hospital, Kristineberg 3, 2100 Copenhagen O, Denmark.
Engh JA; Division of Mental Health and Addiction, Vestfold, Hospital Trust, Postboks 2168, 3103 Tonsberg, Norway.
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Źródło :
Schizophrenia research [Schizophr Res] 2021 Feb; Vol. 228, pp. 190-192. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Urokinase Plasminogen Activator*
Schizophrenia*
Biomarkers ; Case-Control Studies ; Humans ; Inflammation
Raport
Tytuł :
Small-Molecule Inhibition of the uPAR ⋅ uPA Interaction by Conformational Selection.
Autorzy :
Xu D; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Bum-Erdene K; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Leth JM; Finsen Laboratory, Rigshospitalet, 2200, Copenhagen N, Denmark.; Biotech Research and Innovation Centre, University of Copenhagen, 2200, Copenhagen N, Denmark.
Ghozayel MK; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Ploug M; Finsen Laboratory, Rigshospitalet, 2200, Copenhagen N, Denmark.; Biotech Research and Innovation Centre, University of Copenhagen, 2200, Copenhagen N, Denmark.
Meroueh SO; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
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Źródło :
ChemMedChem [ChemMedChem] 2021 Jan 19; Vol. 16 (2), pp. 377-387. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Receptors, Urokinase Plasminogen Activator/*antagonists & inhibitors
Small Molecule Libraries/*pharmacology
Urokinase-Type Plasminogen Activator/*antagonists & inhibitors
Binding Sites/drug effects ; Cheminformatics ; Dose-Response Relationship, Drug ; Humans ; Models, Molecular ; Molecular Conformation ; Receptors, Urokinase Plasminogen Activator/metabolism ; Small Molecule Libraries/chemistry ; Urokinase-Type Plasminogen Activator/metabolism
Czasopismo naukowe
Tytuł :
Plasma suPAR may help to distinguish between chronic pancreatitis and pancreatic cancer.
Autorzy :
Aronen A; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Aittoniemi J; Fimlab Laboratories, Tampere, Finland.
Huttunen R; Department of Internal Medicine, Tampere University Hospital, Tampere, Finland.
Nikkola A; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Rinta-Kiikka I; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Radiology, Tampere University Hospital, Tampere, Finland.
Nikkola J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Limnell O; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Nordback I; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Sand J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.
Laukkarinen J; Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland.; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
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Źródło :
Scandinavian journal of gastroenterology [Scand J Gastroenterol] 2021 Jan; Vol. 56 (1), pp. 81-85. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Pancreatic Neoplasms*/diagnosis
Receptors, Urokinase Plasminogen Activator*/blood
Area Under Curve ; Biomarkers ; Humans ; Prognosis ; Prospective Studies ; ROC Curve
Czasopismo naukowe
Tytuł :
Serum level of soluble urokinase plasminogen activator receptor (suPAR) as a disease severity marker of myasthenia gravis: a pilot study.
Autorzy :
Uzawa A; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kojima Y; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.; Department of Neurology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Ozawa Y; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Yasuda M; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Onishi Y; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Akamine H; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Kawaguchi N; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.; Department of Neurology, Dowa Institute of Clinical Neuroscience, Neurology Clinic Chiba, Chiba, Japan.
Himuro K; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.; Department of Neurology, Matsudo Neurology Clinic, Chiba, Japan.
Kuwabara S; Department of Neurology, Graduate School of Medicine, Chiba University, Chiba, Japan.
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Źródło :
Clinical and experimental immunology [Clin Exp Immunol] 2020 Dec; Vol. 202 (3), pp. 321-324. Date of Electronic Publication: 2020 Aug 10.
Typ publikacji :
Journal Article
MeSH Terms :
Myasthenia Gravis*/blood
Myasthenia Gravis*/immunology
Receptors, Urokinase Plasminogen Activator*/blood
Receptors, Urokinase Plasminogen Activator*/immunology
Severity of Illness Index*
Aged ; Biomarkers/blood ; Female ; Humans ; Male ; Middle Aged ; Pilot Projects
Czasopismo naukowe
Tytuł :
TLR4 Response to LPS Is Reinforced by Urokinase Receptor.
Autorzy :
Kiyan Y; Nephrology Department, Hannover Medical School, Hannover, Germany.
Tkachuk S; Nephrology Department, Hannover Medical School, Hannover, Germany.
Rong S; Phenos GmbH, Hannover, Germany.
Gorrasi A; Nouscom, Rome, Italy.
Ragno P; Department of Chemistry and Biology, University of Salerno, Salerno, Italy.
Dumler I; Nephrology Department, Hannover Medical School, Hannover, Germany.
Haller H; Nephrology Department, Hannover Medical School, Hannover, Germany.
Shushakova N; Nephrology Department, Hannover Medical School, Hannover, Germany.; Phenos GmbH, Hannover, Germany.
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Źródło :
Frontiers in immunology [Front Immunol] 2020 Dec 09; Vol. 11, pp. 573550. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial Cells/*drug effects
Inflammation/*metabolism
Lipopolysaccharides/*pharmacology
Macrophages, Peritoneal/*drug effects
Receptors, Urokinase Plasminogen Activator/*metabolism
Sepsis/*metabolism
Toll-Like Receptor 4/*metabolism
Animals ; CD36 Antigens/metabolism ; Cytokines/metabolism ; Disease Models, Animal ; Epithelial Cells/metabolism ; Epithelial Cells/microbiology ; Humans ; Inflammation/genetics ; Inflammation/microbiology ; Inflammation/prevention & control ; Inflammation Mediators/metabolism ; Macrophages, Peritoneal/metabolism ; Macrophages, Peritoneal/microbiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/metabolism ; RAW 264.7 Cells ; Receptors, Urokinase Plasminogen Activator/genetics ; Sepsis/genetics ; Sepsis/microbiology ; Sepsis/prevention & control ; Signal Transduction ; Toll-Like Receptor 4/genetics
Czasopismo naukowe
Tytuł :
The cAMP-ERK1/2 signaling pathway regulates urokinase-type plasminogen activator-induced bovine granulosa cell proliferation.
Autorzy :
Zhao Y; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Yu B; Basic Medical College, Inner Mongolia Medical University, Hohhot, China.
Liu X; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Hu J; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Yang Y; Institute of Animal Husbandry, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, China.
Namei E; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Yang B; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Bai Y; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
Qian Y; Inner Mongolia of Agricultural and Animal Husbandry Science, Hohhot, China.
Li H; College of Veterinary Medicine, Inner Mongolia Agricultural University, Hohhot, China.; Inner Mongolia Key Laboratory of Basic Veterinary Science, Inner Mongolia Agricultural University, Hohhot, China.
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Źródło :
Reproduction (Cambridge, England) [Reproduction] 2020 Dec; Vol. 160 (6), pp. 853-862.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Cyclic AMP/*metabolism
Granulosa Cells/*cytology
Mitogen-Activated Protein Kinase 1/*metabolism
Mitogen-Activated Protein Kinase 3/*metabolism
Receptors, Urokinase Plasminogen Activator/*metabolism
Urokinase-Type Plasminogen Activator/*metabolism
Animals ; Cattle ; Female ; Granulosa Cells/metabolism ; Mitogen-Activated Protein Kinase 1/genetics ; Mitogen-Activated Protein Kinase 3/genetics ; Phosphorylation ; Receptors, Urokinase Plasminogen Activator/genetics ; Signal Transduction ; Urokinase-Type Plasminogen Activator/genetics
Czasopismo naukowe
Tytuł :
Urokinase-type plasminogen activator receptor is required for impairing toll-like receptor 7 signaling on macrophage efferocytosis in lupus.
Autorzy :
Li J; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China.
Pan Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China.
Li D; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China.
Xia X; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China.
Jiang Q; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China.
Dou H; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, China.
Hou Y; The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China; Jiangsu Key Laboratory of Molecular Medicine, Nanjing 210093, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2020 Nov; Vol. 127, pp. 38-45. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Phagocytosis*
Signal Transduction*
Lupus Erythematosus, Systemic/*pathology
Macrophages, Peritoneal/*metabolism
Receptors, Urokinase Plasminogen Activator/*metabolism
Toll-Like Receptor 7/*metabolism
Animals ; Female ; Humans ; Imiquimod ; Jurkat Cells ; MAP Kinase Signaling System ; Macrophages, Peritoneal/pathology ; Mice ; Mice, Inbred BALB C ; Peptides/pharmacology ; RAW 264.7 Cells ; Receptors, Urokinase Plasminogen Activator/deficiency ; Up-Regulation
Czasopismo naukowe
Tytuł :
Assessment of saliva and gingival crevicular fluid soluble urokinase plasminogen activator receptor (suPAR), galectin-1, and TNF-α levels in periodontal health and disease.
Autorzy :
Taşdemir İ; Department of Periodontology, Faculty of Dentistry, Istanbul Aydin University, Istanbul, Turkey.; Department of Periodontology, Faculty of Dentistry, Izmir Katip Çelebi University, Izmir, Turkey.
Erbak Yılmaz H; Department of Medical Biochemistry, School of Medicine, Izmir Katip Çelebi University, Izmir, Turkey.
Narin F; Department of Medical Biochemistry, School of Medicine, Izmir Katip Çelebi University, Izmir, Turkey.
Sağlam M; Department of Periodontology, Faculty of Dentistry, Izmir Katip Çelebi University, Izmir, Turkey.
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Źródło :
Journal of periodontal research [J Periodontal Res] 2020 Oct; Vol. 55 (5), pp. 622-630. Date of Electronic Publication: 2020 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Chronic Periodontitis*/metabolism
Galectin 1*
Gingivitis*/metabolism
Receptors, Urokinase Plasminogen Activator*/metabolism
Tumor Necrosis Factor-alpha*/metabolism
Gingival Crevicular Fluid ; Humans ; Inflammation ; Plasminogen ; Saliva/metabolism ; Urokinase-Type Plasminogen Activator
Czasopismo naukowe
Tytuł :
Expression of urokinase-type plasminogen activator system in non-metastatic prostate cancer.
Autorzy :
Kimura S; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Department of Urology, Jikei University School of Medicine, Tokyo, Japan.
D'Andrea D; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Iwata T; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.
Foerster B; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Department of Urology, Kantonsspital Winterthur, Winterthur, Switzerland.
Janisch F; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Parizi MK; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Department of Urology, Shariati Hospital, Tehran University of Medical Sciences, Teheran, Iran.
Moschini M; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Klinik für Urologie, Luzerner Kantonsspital, Lucerne, Switzerland.; Urological Research Institute, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Briganti A; Urological Research Institute, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
Babjuk M; Department of Urology, Hospital Motol, Second Faculty of Medicine, Charles University, Prague, Czech Republic.
Chlosta P; Department of Urology, Jagiellonian University, Kraków, Poland.
Karakiewicz PI; Division of Urology, University of Montreal Health Center, Montreal, QC, Canada.
Enikeev D; Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Rapoport LM; Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Seebacher V; Department of Gynecology and Gynecologic Oncology, Medical University of Vienna, Vienna, Austria.
Egawa S; Department of Urology, Jikei University School of Medicine, Tokyo, Japan.
Abufaraj M; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.; Division of Urology, Department of Special Surgery, Jordan University Hospital, The University of Jordan, Amman, Jordan.
Shariat SF; Department of Urology and Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. .; Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia. .; Department of Urology, Weill Cornell Medical College, New York, NY, USA. .; Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX, USA. .; Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria. .
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Źródło :
World journal of urology [World J Urol] 2020 Oct; Vol. 38 (10), pp. 2501-2511. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Journal Article
MeSH Terms :
Prostatectomy*
Biomarkers, Tumor/*physiology
Neoplasm Recurrence, Local/*etiology
Plasminogen Activator Inhibitor 1/*physiology
Prostatic Neoplasms/*etiology
Prostatic Neoplasms/*surgery
Receptors, Urokinase Plasminogen Activator/*physiology
Urokinase-Type Plasminogen Activator/*physiology
Aged ; Biomarkers, Tumor/biosynthesis ; Humans ; Male ; Middle Aged ; Neoplasm Recurrence, Local/epidemiology ; Plasminogen Activator Inhibitor 1/biosynthesis ; Prognosis ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/metabolism ; Receptors, Urokinase Plasminogen Activator/biosynthesis ; Retrospective Studies ; Urokinase-Type Plasminogen Activator/biosynthesis
Czasopismo naukowe
Tytuł :
Soluble urokinase plasminogen activator receptor (suPAR) is lower in disease-free patients but cannot rule out incident disease in patients with suspected cancer.
Autorzy :
Rasmussen LJH; Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegaard Allé 30, DK-2650 Hvidovre, Denmark; Department of Psychology and Neuroscience, Duke University, 2020 W Main St, Suite 201, Durham, NC 27708, USA. Electronic address: .
Schultz M; Department of Cardiology, Copenhagen University Hospital Herlev and Gentofte, Borgmester Ib Juuls Vej 1, DK-2700 Herlev, Denmark.
Iversen K; Department of Cardiology, Copenhagen University Hospital Herlev and Gentofte, Borgmester Ib Juuls Vej 1, DK-2700 Herlev, Denmark.
Eugen-Olsen J; Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Kettegaard Allé 30, DK-2650 Hvidovre, Denmark.
Helms M; Department of Infectious Diseases, Copenhagen University Hospital Amager and Hvidovre, Kettegaard Allé 30, DK-2650 Hvidovre, Denmark.
David K; Department of Infectious Diseases, Copenhagen University Hospital Amager and Hvidovre, Kettegaard Allé 30, DK-2650 Hvidovre, Denmark.
Kjaer A; Department of Clinical Physiology, Nuclear Medicine & PET, Rigshospitalet, Juliane Maries Vej 8, DK-2100 Copenhagen Ø, Denmark; Cluster for Molecular Imaging, University of Copenhagen, Blegdamsvej 3, DK-2200 Copenhagen N, Denmark.
Lebech AM; Department of Infectious Diseases, Rigshospitalet, Esther Møllers Vej 6, DK-2100 Copenhagen Ø, Denmark; Department of Clinical Medicine, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.
Kronborg G; Department of Infectious Diseases, Copenhagen University Hospital Amager and Hvidovre, Kettegaard Allé 30, DK-2650 Hvidovre, Denmark; Department of Clinical Medicine, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.
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Źródło :
Clinical biochemistry [Clin Biochem] 2020 Oct; Vol. 84, pp. 31-37. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article
MeSH Terms :
Neoplasms/*diagnosis
Neoplasms/*metabolism
Receptors, Urokinase Plasminogen Activator/*analysis
Aged ; Area Under Curve ; Biomarkers/blood ; Cohort Studies ; Female ; Humans ; Male ; Middle Aged ; Prognosis ; Prospective Studies ; Receptors, Urokinase Plasminogen Activator/blood ; Risk Assessment
Czasopismo naukowe
Tytuł :
Evaluation of the relationship between KIM-1 and suPAR levels and clinical severity in COVID-19 patients: A different perspective on suPAR.
Autorzy :
Kerget B; Department of Pulmonary Diseases, Ataturk University School of Medicine, Yakutiye, Erzurum, Turkey.
Kerget F; Department of Infection Diseases and Clinical Microbiology, Health Sciences University Erzurum Regional Education and Research Hospital, Yakutiye, Erzurum, Turkey.
Aksakal A; Department of Pulmonary Diseases, Health Sciences University Erzurum Regional Education and Research Hospital, Yakutiye, Erzurum, Turkey.
Aşkın S; Department of Biochemistry, Ataturk University School of Medicine, Yakutiye, Erzurum, Turkey.
Uçar EY; Department of Pulmonary Diseases, Ataturk University School of Medicine, Yakutiye, Erzurum, Turkey.
Sağlam L; Department of Pulmonary Diseases, Ataturk University School of Medicine, Yakutiye, Erzurum, Turkey.
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Źródło :
Journal of medical virology [J Med Virol] 2021 Sep; Vol. 93 (9), pp. 5568-5573. Date of Electronic Publication: 2021 May 28.
Typ publikacji :
Journal Article
MeSH Terms :
SARS-CoV-2*
COVID-19/*blood
Hepatitis A Virus Cellular Receptor 1/*blood
Receptors, Urokinase Plasminogen Activator/*blood
Adult ; Aged ; Biomarkers/blood ; COVID-19/diagnosis ; Female ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Prognosis ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Soluble urokinase plasminogen activator receptor (suPAR) predicts critical illness and kidney failure in patients admitted to the intensive care unit.
Autorzy :
Reisinger AC; Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Niedrist T; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Posch F; Department of Internal Medicine, Division of Oncology, Medical University of Graz, Graz, Austria.
Hatzl S; Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.; Department of Internal Medicine, Division of Hematology, Medical University of Graz, Graz, Austria.
Hackl G; Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Prattes J; Department of Internal Medicine, Section of Infectious Diseases and Tropical Medicine, Medical University of Graz, Graz, Austria.
Schilcher G; Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Meißl AM; Department of Internal Medicine, Division of Nephrology, Medical University of Graz, Graz, Austria.
Raggam RB; Department of Internal Medicine, Division of Angiology, Medical University of Graz, Graz, Austria.
Herrmann M; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Eller P; Department of Internal Medicine, Intensive Care Unit, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria. .
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Źródło :
Scientific reports [Sci Rep] 2021 Sep 01; Vol. 11 (1), pp. 17476. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19/*blood
Critical Illness/*mortality
Kidney Diseases/*blood
Receptors, Urokinase Plasminogen Activator/*blood
Renal Insufficiency/*mortality
Aged ; Female ; Humans ; Immunoturbidimetry ; Intensive Care Units ; Male ; Middle Aged ; Mortality ; Odds Ratio ; Organ Dysfunction Scores ; Prognosis ; Prospective Studies ; Renal Insufficiency/blood ; Survival Analysis
Czasopismo naukowe
Tytuł :
Urokinase Plasminogen Activator Receptor-Mediated Targeting of a Stable Nanocomplex Coupled with Specific Peptides for Imaging of Cancer.
Autorzy :
Shahdeo D; DBT-National Institute of Animal Biotechnology, Hyderabad-500032, Telangana, India.
Chandra AB; DBT-National Institute of Animal Biotechnology, Hyderabad-500032, Telangana, India.
Gandhi S; DBT-National Institute of Animal Biotechnology, Hyderabad-500032, Telangana, India.; Amity Institute of Biotechnology, Amity University, Noida-201301, Uttar Pradesh, India.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Aug 31; Vol. 93 (34), pp. 11868-11877. Date of Electronic Publication: 2021 Aug 19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breast Neoplasms*
Metal Nanoparticles*/toxicity
Gold ; Humans ; Male ; Peptides ; Receptors, Urokinase Plasminogen Activator ; Urokinase-Type Plasminogen Activator
Czasopismo naukowe
Tytuł :
Prognostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor and High-Sensitivity C-Reactive Protein on Postoperative Mortality in Patients Undergoing Elective On-Pump Cardiac Surgery.
Autorzy :
Rasmussen SR; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address: .
Nielsen RV; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Eriksson F; Section of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Dons M; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Vedel AG; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Buggeskov KB; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Møgelvang R; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Clinical Cardiovascular Research Unit, Svendborg, University of Southern Denmark, Svendborg, Denmark.
Ostrowski SR; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Ravn HB; Department of Cardiothoracic Anesthesiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 2021 Aug; Vol. 35 (8), pp. 2415-2423. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
C-Reactive Protein*
Cardiac Surgical Procedures*/adverse effects
Adult ; Biomarkers ; Humans ; Prognosis ; Receptors, Urokinase Plasminogen Activator ; Risk Assessment
Czasopismo naukowe
Tytuł :
Bioluminescence Imaging of Urokinase-Type Plasminogen Activator Activity in Vitro and in Tumors.
Autorzy :
Chen Y; Hefei National Laboratory of Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.
Wu C; Hefei National Laboratory of Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.
Wang C; Hefei National Laboratory of Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.
Zhang T; School of Life Sciences, University of Science and Technology of China, 443 Huangshan Road, Hefei, Anhui 230027, China.
Hua Y; Department of Obstetrics and Gynaecology, Zhongda Hospital, School of Medicine, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210009, China.
Shen Y; Department of Obstetrics and Gynaecology, Zhongda Hospital, School of Medicine, Southeast University, 87 Dingjiaqiao, Nanjing, Jiangsu 210009, China.
Liang G; Hefei National Laboratory of Physical Sciences at Microscale, Department of Chemistry, University of Science and Technology of China, 96 Jinzhai Road, Hefei, Anhui 230026, China.; State Key Laboratory of Bioelectronics, School of Biological Sciences and Medical Engineering, Southeast University, 2 Sipailou Road, Nanjing, Jiangsu 210096, China.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Jul 27; Vol. 93 (29), pp. 9970-9973. Date of Electronic Publication: 2021 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Neoplasms*/diagnostic imaging
Urokinase-Type Plasminogen Activator*
Humans ; Receptors, Urokinase Plasminogen Activator
Czasopismo naukowe
Tytuł :
Preoperative Levels of the Soluble Urokinase-Type Plasminogen Activator Receptor as Predictor for New Episodes of Atrial Fibrillation After Vascular Surgery.
Autorzy :
Lazarević M; Clinic of Cardiovascular and Transplant Surgery, 256420Clinical Center Niš, Niš, Serbia.
Golubović M; Department for Cardiac Surgery, Clinic for Anaesthesiology and Intensive Therapy, 256420Clinical Center Niš, Niš, Serbia.; Medical School of Nis, University of Niš, Niš, Serbia.
Milić D; Clinic of Cardiovascular and Transplant Surgery, 256420Clinical Center Niš, Niš, Serbia.; Medical School of Nis, University of Niš, Niš, Serbia.
Stanojević D; Clinic for Cardiology, 256420Clinical Center Niš, Niš, Serbia.
Kostić T; Medical School of Nis, University of Niš, Niš, Serbia.; Clinic for Cardiology, 256420Clinical Center Niš, Niš, Serbia.
Đorđević M; Medical School of Nis, University of Niš, Niš, Serbia.; Clinic for Endocrine Surgery, Clinical Center Niš, Niš, Serbia.
Marjanović V; Medical School of Nis, University of Niš, Niš, Serbia.; Department for Pediatric Surgery, Clinic for Anaesthesiology and Intensive Therapy, Clinical Center Niš, Niš, Serbia.
Perić V; Department for Cardiac Surgery, Clinic for Anaesthesiology and Intensive Therapy, 256420Clinical Center Niš, Niš, Serbia.
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Źródło :
Vascular and endovascular surgery [Vasc Endovascular Surg] 2021 Jul; Vol. 55 (5), pp. 461-466. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
MeSH Terms :
Atrial Fibrillation/*etiology
Receptors, Urokinase Plasminogen Activator/*blood
Vascular Diseases/*surgery
Vascular Surgical Procedures/*adverse effects
Aged ; Aged, 80 and over ; Atrial Fibrillation/diagnosis ; Biomarkers/blood ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome ; Vascular Diseases/blood ; Vascular Diseases/diagnosis
Czasopismo naukowe

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