Temat: "Receptors, Vasoactive Intestinal Polypeptide, Type I" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Impact Assessment of Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) and Hemostatic Sponge on Vascular Anastomosis Regeneration in Rats.
Autorzy:: Fazekas LA; Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond ut 22, H-4032 Debrecen, Hungary.
Szabo B; Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond ut 22, H-4032 Debrecen, Hungary.
Szegeczki V; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.
Filler C; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.
Varga A; Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond ut 22, H-4032 Debrecen, Hungary.
Godo ZA; Department of Information Technology, Faculty of Informatics, University of Debrecen, Kassai ut 26, H-4028 Debrecen, Hungary.
Toth G; Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, Dom ter 8, H-6720 Szeged, Hungary.
Reglodi D; HUN-REN-PTE PACAP Research Group, Department of Anatomy, Medical School, University of Pecs, Szigeti ut 12, H-7624 Pecs, Hungary.
Juhasz T; Department of Anatomy, Histology and Embryology, Faculty of Medicine, University of Debrecen, Nagyerdei krt. 98, H-4032 Debrecen, Hungary.
Nemeth N; Department of Operative Techniques and Surgical Research, Faculty of Medicine, University of Debrecen, Moricz Zsigmond ut 22, H-4032 Debrecen, Hungary.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 24; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 24.
Typ publikacji:: Journal Article
MeSH Terms:: Pituitary Adenylate Cyclase-Activating Polypeptide*/pharmacology
Hemostatics*/pharmacology
Rats ; Animals ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism

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Skocz do pozycji: 2.

Tytuł:: Development of a New Enzyme-Linked Immunosorbent Assay (ELISA) for Measuring the Content of PACAP in Mammalian Tissue and Plasma.
Autorzy:: Obara EAA; Department of Clinical Biochemistry, Faculty of Health Sciences, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Nielsine Nielsens Vej 4, 2400 Copenhagen, NV, Denmark.
Georg B; Department of Clinical Biochemistry, Faculty of Health Sciences, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Nielsine Nielsens Vej 4, 2400 Copenhagen, NV, Denmark.
Hannibal J; Department of Clinical Biochemistry, Faculty of Health Sciences, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Nielsine Nielsens Vej 4, 2400 Copenhagen, NV, Denmark.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 12; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:: Journal Article
MeSH Terms:: Pituitary Adenylate Cyclase-Activating Polypeptide*
Migraine Disorders*
Animals ; Humans ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide ; Receptors, Vasoactive Intestinal Polypeptide, Type I ; Receptors, Vasoactive Intestinal Peptide, Type II ; Mammals ; Enzyme-Linked Immunosorbent Assay ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I ; Vasoactive Intestinal Peptide

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Tytuł:: Altered Hippocampal and Striatal Expression of Endothelial Markers and VIP/PACAP Neuropeptides in a Mouse Model of Systemic Lupus Erythematosus.
Autorzy:: Lee J; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Science, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Thomas Broome S; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Science, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Jansen MI; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Science, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Mandwie M; Gene Therapy Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
Logan GJ; Gene Therapy Research Unit, Children's Medical Research Institute, Faculty of Medicine and Health, The University of Sydney and Sydney Children's Hospitals Network, Westmead, NSW 2145, Australia.
Marzagalli R; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Science, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Musumeci G; Department of Biomedical and Biotechnological Sciences, Anatomy, Histology and Movement Sciences Section, School of Medicine, University of Catania, 95124 Catania, Italy.
Castorina A; Laboratory of Cellular and Molecular Neuroscience (LCMN), School of Life Science, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Jul 05; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 05.
Typ publikacji:: Journal Article
MeSH Terms:: Vasoactive Intestinal Peptide*/metabolism
Lupus Erythematosus, Systemic*
Mice ; Animals ; Pituitary Adenylate Cyclase-Activating Polypeptide/metabolism ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I ; Receptors, Vasoactive Intestinal Peptide, Type II

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Skocz do pozycji: 4.

Tytuł:: lncRNA-AC079061.1/VIPR1 axis may suppress the development of hepatocellular carcinoma: a bioinformatics analysis and experimental validation.
Autorzy:: Lin XH; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Liver Disease, Shanghai, 200032, China.
Zhang DY; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Liver Disease, Shanghai, 200032, China.
Liu ZY; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Liver Disease, Shanghai, 200032, China.
Tang WQ; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Liver Disease, Shanghai, 200032, China.
Chen RX; Liver Cancer Institute, Zhongshan Hospital, Fudan University and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, 200032, China.
Li DP; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.; Shanghai Institute of Liver Disease, Shanghai, 200032, China.
Weng S; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .; Shanghai Institute of Liver Disease, Shanghai, 200032, China. .
Dong L; Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, 200032, China. .; Shanghai Institute of Liver Disease, Shanghai, 200032, China. .; Pokaż więcej
Źródło:: Journal of translational medicine [J Transl Med] 2022 Aug 29; Vol. 20 (1), pp. 379. Date of Electronic Publication: 2022 Aug 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
Computational Biology ; Gene Expression Regulation, Neoplastic ; Humans ; Receptors, Vasoactive Intestinal Polypeptide, Type I/genetics ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism ; Tumor Microenvironment

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Skocz do pozycji: 5.

Tytuł:: VIP/VPAC Axis Expression in Immune-Mediated Inflammatory Disorders: Associated miRNA Signatures.
Autorzy:: Lamana A; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Castro-Vázquez D; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
de la Fuente H; Department of Immunology, Instituto de Investigación Princesa, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Triguero-Martínez A; Department of Rheumatology, Instituto de Investigación Princesa Madrid, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Martínez-Hernández R; Department of Endocrinology, Instituto de Investigación Princesa, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Revenga M; Department of Rheumatology, Hospital Universitario Ramón y Cajal, 28034 Madrid, Spain.; Department of Medicine and Medical Specialties, Universidad de Alcalá, 28805 Alcalá de Henares, Spain.
Villanueva-Romero R; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Llamas-Velasco M; Department of Dermatology, Instituto de Investigación Princesa, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Chicharro P; Department of Dermatology, Instituto de Investigación Princesa, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Juarranz Y; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Marazuela M; Department of Endocrinology, Instituto de Investigación Princesa, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Sales-Sanz M; Department of Ophthalmology, Hospital Universitario Ramón y Cajal-IRYCIS, 28034 Madrid, Spain.
García-Vicuña R; Department of Rheumatology, Instituto de Investigación Princesa Madrid, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Tomero E; Department of Rheumatology, Instituto de Investigación Princesa Madrid, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
González-Álvaro I; Department of Rheumatology, Instituto de Investigación Princesa Madrid, Hospital Universitario de La Princesa, 28006 Madrid, Spain.
Martínez C; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Gomariz RP; Department of Cell Biology, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Aug 02; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:: Journal Article
MeSH Terms:: Arthritis, Rheumatoid*/metabolism
MicroRNAs*/genetics
Humans ; Leukocytes, Mononuclear/metabolism ; RNA, Messenger ; Receptors, Vasoactive Intestinal Peptide, Type II/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I/genetics ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism ; Vasoactive Intestinal Peptide/genetics ; Vasoactive Intestinal Peptide/metabolism

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Tytuł:: A Molecular Dynamics Study of Vasoactive Intestinal Peptide Receptor 1 and the Basis of Its Therapeutic Antagonism.
Autorzy:: Latek D; Faculty of Chemistry, University of Warsaw, 02-093 Warsaw, Poland. .
Langer I; Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), Université libre de Bruxelles, B-1070 Brussels, Belgium.
Krzysko K; Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.
Charzewski L; Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Sep 05; Vol. 20 (18). Date of Electronic Publication: 2019 Sep 05.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Design*
Molecular Docking Simulation*
Molecular Dynamics Simulation*
Receptors, Vasoactive Intestinal Polypeptide, Type I/*chemistry
Binding Sites ; Humans ; Ligands ; Molecular Structure ; Protein Binding ; Protein Conformation ; Quantitative Structure-Activity Relationship ; Receptors, Vasoactive Intestinal Polypeptide, Type I/antagonists & inhibitors

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Skocz do pozycji: 7.

Tytuł:: Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors.
Autorzy:: Lu J; Drug Discovery Biology, Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Piper SJ; Drug Discovery Biology, Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Zhao P; Drug Discovery Biology, Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Miller LJ; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ 85259, USA.
Wootten D; Drug Discovery Biology, Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.
Sexton PM; Drug Discovery Biology, Australian Research Council Centre for Cryo-Electron Microscopy of Membrane Proteins, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC 3052, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 22; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Pituitary Adenylate Cyclase-Activating Polypeptide*
Vasoactive Intestinal Peptide*/metabolism
Amino Acid Sequence ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I/metabolism ; Receptors, Vasoactive Intestinal Peptide, Type II ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism ; Signal Transduction

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Skocz do pozycji: 8.

Tytuł:: Upregulation of intestinal mucosal mast cells expressing VPAC1 in close proximity to vasoactive intestinal polypeptide in inflammatory bowel disease and murine colitis.
Autorzy:: Casado-Bedmar M; Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics & Oncology, Linköping University, Linköping, Sweden.
Heil SDS; Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics & Oncology, Linköping University, Linköping, Sweden.
Myrelid P; Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics & Oncology, Linköping University, Linköping, Sweden.; Department of Surgery, County Council of Östergötland, Linköping, Sweden.
Söderholm JD; Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics & Oncology, Linköping University, Linköping, Sweden.; Department of Surgery, County Council of Östergötland, Linköping, Sweden.
Keita ÅV; Department of Clinical and Experimental Medicine, Division of Surgery, Orthopedics & Oncology, Linköping University, Linköping, Sweden.; Pokaż więcej
Źródło:: Neurogastroenterology and motility [Neurogastroenterol Motil] 2019 Mar; Vol. 31 (3), pp. e13503. Date of Electronic Publication: 2018 Nov 08.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Colitis, Ulcerative/*metabolism
Inflammatory Bowel Diseases/*metabolism
Inflammatory Bowel Diseases/*pathology
Intestinal Mucosa/*metabolism
Mast Cells/*metabolism
Mast Cells/*pathology
Receptors, Vasoactive Intestinal Polypeptide, Type I/*biosynthesis
Vasoactive Intestinal Peptide/*biosynthesis
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Cell Count ; Colitis, Ulcerative/chemically induced ; Crohn Disease/metabolism ; Dextran Sulfate ; Female ; Humans ; Ileum/metabolism ; Intestinal Mucosa/pathology ; Male ; Mice, Inbred BALB C ; Middle Aged ; Receptors, Vasoactive Intestinal Polypeptide, Type I/genetics ; Up-Regulation ; Young Adult

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Skocz do pozycji: 9.

Tytuł:: VPAC1 receptors play a dominant role in PACAP-induced vasorelaxation in female mice.
Autorzy:: Ivic I; Department of Anatomy, MTA-PTE PACAP Research Group, Medical School, University of Pecs, Pecs, Hungary.; Department of Physiology and Immunology, Medical School Osijek, University of J.J. Strossmayer, Osijek, Croatia.
Balasko M; Institute for Translational Medicine, Medical School, University of Pecs, Pecs, Hungary.
Fulop BD; Department of Anatomy, MTA-PTE PACAP Research Group, Medical School, University of Pecs, Pecs, Hungary.
Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan.; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Suita, Osaka, Japan.; Division of Bioscience, Institute for Datability Science, Osaka University, Suita, Osaka, Japan.
Toth G; Department of Medical Chemistry, University of Szeged, Szeged, Hungary.
Tamas A; Department of Anatomy, MTA-PTE PACAP Research Group, Medical School, University of Pecs, Pecs, Hungary.
Juhasz T; Department of Anatomy, Histology, and Embryology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Koller A; Department of Physiology, New York Medical College, Valhalla, NY, United States of America.; Department of Neurosurgery, Medical School, University of Pecs, Pecs, Hungary.; Institute of Natural Sciences, Research Group for Sportgenetics and Sportgerontology, University of Physical Education, Budapest, Hungary.
Reglodi D; Department of Anatomy, MTA-PTE PACAP Research Group, Medical School, University of Pecs, Pecs, Hungary.
Solymár M; Institute for Translational Medicine, Medical School, University of Pecs, Pecs, Hungary.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Jan 25; Vol. 14 (1), pp. e0211433. Date of Electronic Publication: 2019 Jan 25 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Vasodilation*/drug effects
Pituitary Adenylate Cyclase-Activating Polypeptide/*genetics
Receptors, Vasoactive Intestinal Polypeptide, Type I/*metabolism
Animals ; Carotid Arteries/drug effects ; Carotid Arteries/physiology ; Female ; Femoral Artery/drug effects ; Femoral Artery/physiology ; Insect Proteins/pharmacology ; Mice ; Mice, Knockout ; Nitroprusside/pharmacology ; Pituitary Adenylate Cyclase-Activating Polypeptide/deficiency ; Pituitary Adenylate Cyclase-Activating Polypeptide/pharmacology ; Receptors, Vasoactive Intestinal Polypeptide, Type I/antagonists & inhibitors ; Vasoactive Intestinal Peptide/pharmacology

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Skocz do pozycji: 10.

Tytuł:: Characterisation of agonist signalling profiles and agonist-dependent antagonism at PACAP-responsive receptors: Implications for drug discovery.
Autorzy:: Tasma Z; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Siow A; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.
Harris PWR; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre and Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Brimble MA; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; School of Chemical Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre and Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.
Hay DL; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre and Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; Department of Pharmacology and Toxicology, University of Otago, Dunedin, New Zealand.
Walker CS; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre and Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand.; Pokaż więcej
Źródło:: British journal of pharmacology [Br J Pharmacol] 2022 Feb; Vol. 179 (3), pp. 435-453. Date of Electronic Publication: 2021 Oct 31.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Migraine Disorders*/metabolism
Pituitary Adenylate Cyclase-Activating Polypeptide*/metabolism
Pituitary Adenylate Cyclase-Activating Polypeptide*/pharmacology
Drug Discovery ; Humans ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I/metabolism ; Receptors, Vasoactive Intestinal Peptide/metabolism ; Receptors, Vasoactive Intestinal Peptide, Type II ; Receptors, Vasoactive Intestinal Polypeptide, Type I ; Vasoactive Intestinal Peptide

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Skocz do pozycji: 11.

Tytuł:: Altered interaction between enteric glial cells and mast cells in the colon of women with irritable bowel syndrome.
Autorzy:: Meira de-Faria F; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Casado-Bedmar M; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Mårten Lindqvist C; Department of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Jones MP; Macquarie University, Sydney, New South Wales, Australia.
Walter SA; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.; Department of Gastroenterology, Linköping University, Linköping, Sweden.
Keita ÅV; Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.; Pokaż więcej
Źródło:: Neurogastroenterology and motility [Neurogastroenterol Motil] 2021 Nov; Vol. 33 (11), pp. e14130. Date of Electronic Publication: 2021 Apr 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Colon/*metabolism
Enteric Nervous System/*metabolism
Irritable Bowel Syndrome/*metabolism
Mast Cells/*metabolism
Neuroglia/*metabolism
Adult ; Female ; Humans ; Intestinal Mucosa/metabolism ; Middle Aged ; Receptors, Vasoactive Intestinal Peptide, Type II/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism ; Young Adult

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Tytuł:: Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP 1-23 .
Autorzy:: Apostol CR; Department of Chemistry and Biochemistry, BIO5, The University of Arizona, 1306 E. University Blvd, Tucson, AZ 85721, USA.
Tanguturi P; Department of Pharmacology, College of Medicine, The University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724, USA.
Szabò LZ; Department of Chemistry and Biochemistry, BIO5, The University of Arizona, 1306 E. University Blvd, Tucson, AZ 85721, USA.
Varela D; Facultat de Quìmica Tarragona, Universitat Rovera I Virgili, 43007 Barcelona, Spain.
Gilmartin T; Facultat de Quìmica Tarragona, Universitat Rovera I Virgili, 43007 Barcelona, Spain.
Streicher JM; Department of Pharmacology, College of Medicine, The University of Arizona, 1501 N. Campbell Ave, Tucson, AZ 85724, USA.
Polt R; Department of Chemistry and Biochemistry, BIO5, The University of Arizona, 1306 E. University Blvd, Tucson, AZ 85721, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Aug 14; Vol. 26 (16). Date of Electronic Publication: 2021 Aug 14.
Typ publikacji:: Journal Article
MeSH Terms:: Glycopeptides/*chemistry
Inflammation/*drug therapy
Neurodegenerative Diseases/*drug therapy
Peptide Fragments/*chemistry
Brain/drug effects ; Brain/metabolism ; Glycopeptides/chemical synthesis ; Glycopeptides/pharmacology ; Humans ; Inflammation/pathology ; Neurodegenerative Diseases/pathology ; Neuroprotective Agents/chemical synthesis ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/pharmacology ; Peptide Fragments/chemical synthesis ; Peptide Fragments/pharmacology ; Peptide Hormones/chemical synthesis ; Peptide Hormones/chemistry ; Peptide Hormones/pharmacology ; Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide, Type I/drug effects ; Receptors, Vasoactive Intestinal Peptide, Type II/antagonists & inhibitors ; Receptors, Vasoactive Intestinal Polypeptide, Type I/drug effects

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Skocz do pozycji: 13.

Tytuł:: VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage.
Autorzy:: Abad C; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, USA.; Inserm U905, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen, Normandy, France.
Jayaram B; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, USA.
Becquet L; Inserm U905, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen, Normandy, France.
Wang Y; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, USA.
O'Dorisio MS; Department of Pediatrics and Holden Comprehensive Cancer Center, RJ and LA Carver College of Medicine, University of Iowa, Iowa City, 52242, IA, USA.
Waschek JA; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, USA.
Tan YV; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, USA. .; Inserm U905, Institute for Research and Innovation in Biomedicine (IRIB), University of Rouen, Normandy, France. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2016 Jun 29; Vol. 13 (1), pp. 169. Date of Electronic Publication: 2016 Jun 29.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cytokines/*metabolism
Encephalomyelitis, Autoimmune, Experimental/*complications
Encephalomyelitis, Autoimmune, Experimental/*genetics
Receptors, Vasoactive Intestinal Polypeptide, Type I/*deficiency
Adoptive Transfer ; Animals ; Central Nervous System/immunology ; Central Nervous System/metabolism ; Central Nervous System/pathology ; Cytokines/genetics ; Disease Models, Animal ; Encephalomyelitis, Autoimmune, Experimental/chemically induced ; Female ; Freund's Adjuvant/toxicity ; Laminin/metabolism ; Lymph Nodes/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myelin-Oligodendrocyte Glycoprotein/toxicity ; Peptide Fragments/toxicity ; RNA, Messenger/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I/genetics ; Spinal Cord/metabolism ; Spinal Cord/pathology ; Th1 Cells/metabolism ; Th1 Cells/pathology ; Th17 Cells/metabolism ; Th17 Cells/pathology ; Time Factors

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Skocz do pozycji: 14.

Tytuł:: High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance.
Autorzy:: Nakata M; Department of Physiology, Division of Integrative Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.
Zhang B; Department of Physiology, Division of Integrative Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.
Yang Y; Department of Physiology, Division of Integrative Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.
Okada T; Department of Biochemistry and Molecular Biology, Division of Gene Therapy, Research Center for Advanced Medical Technology, Nippon Medical School, Tokyo 113-8603, Japan.
Shintani N; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan.
Hashimoto H; Laboratory of Molecular Neuropharmacology, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565-0871, Japan; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University and University of Fukui, Suita, Osaka 565-0871, Japan; Division of Bioscience, Institute for Datability Science, Osaka University, Suita, Osaka 565-0871, Japan.
Yada T; Department of Physiology, Division of Integrative Physiology, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.; Pokaż więcej
Źródło:: Journal of diabetes research [J Diabetes Res] 2016; Vol. 2016, pp. 9321395. Date of Electronic Publication: 2016 Dec 01.
Typ publikacji:: Journal Article
MeSH Terms:: Insulin Resistance*
Diet, High-Fat/*adverse effects
Liver/*metabolism
Pituitary Adenylate Cyclase-Activating Polypeptide/*pharmacology
Receptor-Like Protein Tyrosine Phosphatases, Class 2/*genetics
Receptors, Vasoactive Intestinal Polypeptide, Type I/*physiology
Animals ; Gene Expression/drug effects ; Hypoglycemic Agents ; Liver/chemistry ; Liver/drug effects ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Mice, Knockout ; Pituitary Adenylate Cyclase-Activating Polypeptide/deficiency ; Pituitary Adenylate Cyclase-Activating Polypeptide/genetics ; RNA, Messenger/analysis ; Receptors, Vasoactive Intestinal Polypeptide, Type I/antagonists & inhibitors ; Receptors, Vasoactive Intestinal Polypeptide, Type I/genetics

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Skocz do pozycji: 15.

Tytuł:: Vasoactive intestinal peptide axis is dysfunctional in patients with Graves' disease.
Autorzy:: Carrión M; Departamento de Biología Celular, Facultad de Biología, Universidad Complutense de Madrid, Calle José Antonio Novais, 12, 28040, Madrid, Spain.
Ramos-Leví AM; Servicio de Endocrinología Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa, 28006, Madrid, Spain.
Seoane IV; Departamento de Biología Celular, Facultad de Biología, Universidad Complutense de Madrid, Calle José Antonio Novais, 12, 28040, Madrid, Spain.
Martínez-Hernández R; Servicio de Endocrinología Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa, 28006, Madrid, Spain.
Serrano-Somavilla A; Servicio de Endocrinología Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa, 28006, Madrid, Spain.
Castro D; Departamento de Biología Celular, Facultad de Biología, Universidad Complutense de Madrid, Calle José Antonio Novais, 12, 28040, Madrid, Spain.
Juarranz Y; Departamento de Biología Celular, Facultad de Biología, Universidad Complutense de Madrid, Calle José Antonio Novais, 12, 28040, Madrid, Spain.
González-Álvaro I; Servicio de Reumatología Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa, 28006, Madrid, Spain.
Gomariz RP; Departamento de Biología Celular, Facultad de Biología, Universidad Complutense de Madrid, Calle José Antonio Novais, 12, 28040, Madrid, Spain. .
Marazuela M; Servicio de Endocrinología Hospital Universitario de la Princesa, Instituto de Investigación Sanitaria la Princesa, 28006, Madrid, Spain.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2020 Aug 03; Vol. 10 (1), pp. 13018. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Graves Disease/*metabolism
Vasoactive Intestinal Peptide/*metabolism
Adult ; Female ; Humans ; Male ; Middle Aged ; Receptors, Vasoactive Intestinal Peptide, Type II/metabolism ; Receptors, Vasoactive Intestinal Polypeptide, Type I/metabolism ; Thyroid Hormones/metabolism ; Vasoactive Intestinal Peptide/blood

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Skocz do pozycji: 16.

Tytuł:: A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases.
Autorzy:: Martínez C; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Juarranz Y; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Gutiérrez-Cañas I; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Carrión M; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Pérez-García S; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Villanueva-Romero R; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Castro D; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Lamana A; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Mellado M; Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología (CNB)/CSIC, 28049 Madrid, Spain.
González-Álvaro I; Servicio de Reumatología, Instituto de Investigación Médica, Hospital Universitario La Princesa, 28006 Madrid, Spain.
Gomariz RP; Departamento de Biología Celular, Facultad de Biología y Facultad de Medicina, Universidad Complutense de Madrid, 28040 Madrid, Spain.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 Dec 20; Vol. 21 (1). Date of Electronic Publication: 2019 Dec 20.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Autoimmune Diseases/*immunology
Inflammation/*immunology
Receptors, Vasoactive Intestinal Peptide, Type II/*immunology
Receptors, Vasoactive Intestinal Polypeptide, Type I/*immunology
Vasoactive Intestinal Peptide/*immunology
Animals ; Diabetes Mellitus, Type 1/immunology ; Humans ; Inflammatory Bowel Diseases/immunology ; Rheumatic Diseases/immunology ; Sjogren's Syndrome/immunology

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Skocz do pozycji: 17.

Tytuł:: Immune evasion by Salmonella: exploiting the VPAC1/VIP axis in human monocytes.
Autorzy:: Askar B; University of Duhok, Duhok, Iraq.
Higgins J; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Barrow P; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.
Foster N; School of Veterinary Medicine and Science, University of Nottingham, Nottingham, UK.; Pokaż więcej
Źródło:: Immunology [Immunology] 2019 Nov; Vol. 158 (3), pp. 230-239. Date of Electronic Publication: 2019 Sep 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Immune Evasion*
Monocytes*/immunology
Monocytes*/microbiology
Monocytes*/pathology
Gene Expression Regulation/*immunology
Receptors, Vasoactive Intestinal Polypeptide, Type I/*immunology
Salmonella Infections/*immunology
Salmonella typhimurium/*immunology
Endosomes/immunology ; Endosomes/microbiology ; Endosomes/pathology ; Humans ; Salmonella Infections/pathology ; rab GTP-Binding Proteins/immunology ; rab3A GTP-Binding Protein/immunology

Czasopismo naukowe

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Skocz do pozycji: 18.

Tytuł:: Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients.
Autorzy:: Villanueva-Romero R; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Gutiérrez-Cañas I; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Carrión M; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
González-Álvaro I; Servicio de Reumatología, Instituto de Investigación Sanitaria Hospital La Princesa (IIS-IP), Madrid, Spain.
Rodríguez-Frade JM; Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Mellado M; Departamento de Inmunología y Oncología, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain.
Martínez C; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Gomariz RP; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain.
Juarranz Y; Departamento de Biología Celular, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), Madrid, Spain. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 May 14; Vol. 9 (1), pp. 7383. Date of Electronic Publication: 2019 May 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Arthritis/*immunology
Lymphocyte Activation/*immunology
Receptors, Vasoactive Intestinal Peptide, Type II/*metabolism
Receptors, Vasoactive Intestinal Polypeptide, Type I/*metabolism
T-Lymphocytes, Helper-Inducer/*immunology
Arthritis/blood ; Cell Fractionation ; Cell Membrane/metabolism ; Cell Nucleus/metabolism ; Cells, Cultured ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Follow-Up Studies ; Humans ; Middle Aged ; Primary Cell Culture ; Signal Transduction/immunology ; T-Lymphocytes, Helper-Inducer/cytology ; T-Lymphocytes, Helper-Inducer/metabolism ; Up-Regulation