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Tytuł:
Stable Mammalian Serum Albumins Designed for Bacterial Expression.
Autorzy:
Khersonsky O; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: .
Goldsmith M; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Zaretsky I; Antibody Engineering Unit, Weizmann Institute of Science, Rehovot 7610001, Israel.
Hamer-Rogotner S; Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 7610001, Israel.
Dym O; Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 7610001, Israel.
Unger T; Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 7610001, Israel.
Yona M; Israel Structural Proteomics Center, Weizmann Institute of Science, Rehovot 7610001, Israel.
Fridmann-Sirkis Y; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel.
Fleishman SJ; Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot 7610001, Israel. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Sep 01; Vol. 435 (17), pp. 168191. Date of Electronic Publication: 2023 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Serum Albumin*/genetics
Serum Albumin*/chemistry
Recombinant Proteins*/chemistry
Recombinant Proteins*/genetics
Animals ; Humans ; Disulfides ; Escherichia coli/genetics ; Reproducibility of Results ; Serum Albumin, Human/chemistry ; Serum Albumin, Human/genetics ; Protein Stability
Czasopismo naukowe
Szczegóły
Tytuł:
Protein engineering of a nanoCLAMP antibody mimetic scaffold as a platform for producing bioprocess-compatible affinity capture ligands.
Autorzy:
Suderman RJ; Nectagen, Inc, Kansas City, Kansas, USA. Electronic address: .
Gibson SD; Nectagen, Inc, Kansas City, Kansas, USA; University of Washington, Seattle, Washington, USA.
Strecker M; Nectagen, Inc, Kansas City, Kansas, USA; Two Dot Consulting, Arvada, Colorado, USA.
Bonner AM; Nectagen, Inc, Kansas City, Kansas, USA.
Chao DM; Nectagen, Inc, Kansas City, Kansas, USA.
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 Jul; Vol. 299 (7), pp. 104910. Date of Electronic Publication: 2023 Jun 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Antibodies*/chemistry
Antibodies*/immunology
Antibodies*/metabolism
Chromatography, Affinity*/methods
Ligands*
Protein Engineering*/methods
Recombinant Proteins*/immunology
Recombinant Proteins*/isolation & purification
Recombinant Proteins*/metabolism
Antibody Affinity*
Molecular Mimicry*
Sodium Hydroxide/pharmacology ; Protein Stability/drug effects ; Hot Temperature ; Trypsin/metabolism ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/immunology ; Recombinant Fusion Proteins/metabolism ; Protein Binding
Czasopismo naukowe
Szczegóły
Tytuł:
Kaleidoscope megamolecules synthesis and application using self-assembly technology.
Autorzy:
Zhou S; School of Pharmacy, Jiangsu University, Zhenjiang 212013, PR China. Electronic address: .
Wei Y; School of Pharmacy, Jiangsu University, Zhenjiang 212013, PR China.
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Źródło:
Biotechnology advances [Biotechnol Adv] 2023 Jul-Aug; Vol. 65, pp. 108147. Date of Electronic Publication: 2023 Apr 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Protein Engineering*
Recombinant Proteins*
Technology
Czasopismo naukowe
Szczegóły
Tytuł:
Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin's Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study.
Autorzy:
Wang T; Department of Hematology Center, Beijing Key Laboratory of Pediatric Hematology Oncology, National Key Discipline of Pediatrics (Capital Medical University), Key Laboratory of Major Diseases in Children, Ministry of Education; Hematology Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Nanlishi Road No. 56, Xicheng District, Beijing, 100045, People's Republic of China. .
Zhu X; Department of Hematology, Chinese Academy of Medical Sciences, Hematology Hospital, Heping District, Tianjing, China.
Chen Y; Department of Hematology, Chinese Academy of Medical Sciences, Hematology Hospital, Heping District, Tianjing, China.
Shen S; Department of Hematology, Shanghai Children's Medical Center, Dongfang Road, Shanghai, China.
Tang Y; Department/Center of Hematology-Oncology, Children's Hospital of Zhejiang University School of Medicine, Pediatric Leukemia Diagnostic and Therapeutic Technology Research Center of Zhejiang Province, National Clinical Research Center for Child Health, Gongshu District, Hangzhou City, Zhejiang Province, China.
Zhang J; Department/Center of Hematology-Oncology, Children's Hospital of Zhejiang University School of Medicine, Pediatric Leukemia Diagnostic and Therapeutic Technology Research Center of Zhejiang Province, National Clinical Research Center for Child Health, Gongshu District, Hangzhou City, Zhejiang Province, China.
He Y; Department of Pediatric Hematology/Oncology, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
Zhang H; Department of Pediatric Hematology/Oncology, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Guangzhou, China.
Gao J; Department of Hematology, West China Second University Hospital, Chengdu, Sichuan Province, China.
Fang J; Department of Hematology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, West Yanjiang Road, Guangzhou, China.
Liu R; Department of Hematology, Children's Hospital Capital Institute of Pediatrics, Chaoyang District, Beijing, China.
Wu X; Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun J; Medical Department, Sanofi, Shanghai, China.
Zhang M; Medical Department, Sanofi, Shanghai, China.
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Źródło:
Drugs in R&D [Drugs R D] 2023 Jun; Vol. 23 (2), pp. 129-140. Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Clinical Trial, Phase IV; Journal Article; Multicenter Study
MeSH Terms:
Hyperuricemia*/complications
Hyperuricemia*/drug therapy
Lymphoma, Non-Hodgkin*/complications
Leukemia*/complications
Recombinant Proteins*/adverse effects
Recombinant Proteins*/therapeutic use
Uric Acid ; China ; Humans ; Male ; Female ; Child, Preschool ; Child
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
An affinity tool for the isolation of endogenous active mTORC1 from various cellular sources.
Autorzy:
Ibrahim YH; Araucaria Laboratories, Inc, New York, New York, USA. Electronic address: .
Pantelios S; Department of Immunology, Pathology and Genetics, Uppsala University, Uppsala, Sweden.
Mutvei AP; Department of Immunology, Pathology and Genetics, Uppsala University, Uppsala, Sweden; Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address: .
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Źródło:
The Journal of biological chemistry [J Biol Chem] 2023 May; Vol. 299 (5), pp. 104644. Date of Electronic Publication: 2023 Mar 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mechanistic Target of Rapamycin Complex 1*/chemistry
Mechanistic Target of Rapamycin Complex 1*/isolation & purification
Mechanistic Target of Rapamycin Complex 1*/metabolism
Monomeric GTP-Binding Proteins*/chemistry
Monomeric GTP-Binding Proteins*/genetics
Monomeric GTP-Binding Proteins*/metabolism
Recombinant Proteins*/genetics
Recombinant Proteins*/metabolism
Biotechnology*/methods
Animals ; Cattle ; Humans ; Mice ; Mammals/metabolism ; Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/metabolism ; Models, Molecular
Czasopismo naukowe
Szczegóły
Tytuł:
Characterization of beta subunit variants of recombinant human chorionic gonadotrophin.
Autorzy:
Deng Q; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
He L; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Xu F; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Deng Q; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Xu T; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Jiang J; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Hu Z; Livzon MabPharm Inc., Zhuhai, Guangdong, China.
Yang J; Livzon MabPharm Inc., Zhuhai, Guangdong, China. Electronic address: .
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Źródło:
Analytical biochemistry [Anal Biochem] 2023 May 01; Vol. 668, pp. 115089. Date of Electronic Publication: 2023 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chorionic Gonadotropin, beta Subunit, Human*/chemistry
Chorionic Gonadotropin, beta Subunit, Human*/pharmacology
Recombinant Proteins*/chemistry
Recombinant Proteins*/pharmacology
Humans ; Glycosylation ; HEK293 Cells ; Electrophoresis, Polyacrylamide Gel
Czasopismo naukowe
Szczegóły
Tytuł:
An ELISA-based assay for determining haemagglutinin potency in egg, cell, or recombinant protein derived influenza vaccines.
Autorzy:
Bodle J; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Vandenberg K; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Laurie K; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.
Barr IG; Collaborating Centre for Reference and Research on Influenza, World Health Organisation, Melbourne, VIC, Australia.
Zhang Y; Vaccine Product Development, CSL Seqirus Ltd, Holly Springs, NC, United States.
Rockman S; Vaccine Product Development, CSL Seqirus Ltd, Parkville, VIC, Australia.; Department of Immunology and Microbiology, University of Melbourne, Parkville, VIC, Australia.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Mar 22; Vol. 14, pp. 1147028. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme-Linked Immunosorbent Assay*/methods
Hemagglutinins*/chemistry
Influenza Vaccines*/chemistry
Influenza Vaccines*/immunology
Influenza Vaccines*/therapeutic use
Recombinant Proteins*/chemistry
Recombinant Proteins*/metabolism
Eggs*
Cells*/chemistry
Cells*/immunology
Animals ; Humans ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/immunology ; Hemagglutinin Glycoproteins, Influenza Virus ; Immune Sera ; Influenza, Human/prevention & control ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
Supplementation of recombinant cellulases with LPMOs and CDHs improves consolidated bioprocessing of cellulose.
Autorzy:
Smuts IE; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Blakeway NJ; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
Rose SH; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
den Haan R; Department of Biotechnology, University of the Western Cape, Bellville 7530, South Africa.
Viljoen-Bloom M; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa.
van Zyl WH; Department of Microbiology, Stellenbosch University, Stellenbosch 7600, South Africa. Electronic address: .
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Źródło:
Enzyme and microbial technology [Enzyme Microb Technol] 2023 Mar; Vol. 164, pp. 110171. Date of Electronic Publication: 2022 Dec 16.
Typ publikacji:
Journal Article
MeSH Terms:
Cellulases*/chemistry
Cellulases*/metabolism
Cellulose*/metabolism
Dietary Supplements*
Recombinant Proteins*/chemistry
Recombinant Proteins*/metabolism
Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Secreting recombinant barnase by Lactococcus lactis and its application in reducing RNA from forages.
Autorzy:
Ai Y; Anhui Fermented Food Engineering Research Center, School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Li X; Anhui Fermented Food Engineering Research Center, School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Wu X; Anhui Fermented Food Engineering Research Center, School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Montalbán-López M; Department of Microbiology, Faculty of Sciences, University of Granada, Granada 18071, Spain.
Zheng Z; Key Laboratory for Agricultural Products Processing of Anhui Province, School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China.
Mu D; Anhui Fermented Food Engineering Research Center, School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China; Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China. Electronic address: .
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Źródło:
Enzyme and microbial technology [Enzyme Microb Technol] 2023 Mar; Vol. 164, pp. 110191. Date of Electronic Publication: 2022 Dec 31.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Proteins*/genetics
Bacterial Proteins*/metabolism
Lactococcus lactis*/enzymology
Lactococcus lactis*/genetics
Ribonucleases*/genetics
Ribonucleases*/chemistry
Ribonucleases*/metabolism
RNA*/metabolism
Recombinant Proteins*/genetics
Recombinant Proteins*/metabolism
Plasmids
Czasopismo naukowe
Szczegóły
Tytuł:
High-yield recombinant bacterial expression of N-labeled, serine-16 phosphorylated, murine amelogenin using a modified third generation genetic code expansion protocol.
Autorzy:
Buchko GW; Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, USA.; School of Molecular Biosciences, Washington State University, Pullman, Washington, USA.
Zhou M; Earth and Biological Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, USA.
Vesely CH; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA.
Tao J; Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, USA.
Shaw WJ; Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington, USA.
Mehl RA; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA.
Cooley RB; Department of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon, USA.
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Źródło:
Protein science : a publication of the Protein Society [Protein Sci] 2023 Feb; Vol. 32 (2), pp. e4560.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Amelogenin*/genetics
Amelogenin*/chemistry
Amelogenin*/metabolism
Escherichia coli*/metabolism
Genetic Code*/genetics
Genetic Code*/physiology
Recombinant Proteins*/genetics
Recombinant Proteins*/chemistry
Serine*
Animals ; Mice ; Phosphoserine
Czasopismo naukowe
Szczegóły
Tytuł:
Biological activity of a new recombinant human coagulation factor VIII and its efficacy in a small animal model.
Autorzy:
Wu J; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Zhang H; Beijing Tiantan Biological Products Co. Ltd., 100024, Beijing, China.
Lian T; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Ding Y; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Song C; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Li D; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Wu L; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China.
Lei T; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China. Electronic address: .
Liang H; Chengdu Rongsheng Pharmaceuticals Co. Ltd., 610041, Chengdu, China; Beijing Tiantan Biological Products Co. Ltd., 100024, Beijing, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Jan 15; Vol. 640, pp. 80-87. Date of Electronic Publication: 2022 Dec 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Factor VIII*/pharmacology
Factor VIII*/therapeutic use
Recombinant Proteins*/pharmacology
Recombinant Proteins*/therapeutic use
Animals ; Humans ; Mice ; Hemophilia A/drug therapy ; Hemorrhage ; Models, Animal
Czasopismo naukowe
Szczegóły
Tytuł:
A fast, efficient, and scalable method for purifying recombinant SARS-CoV-2 spike protein.
Autorzy:
Butani N; Department of Chemical Engineering, McMaster University, Hamilton, ON L8S 4L7, Canada.
Xu Y; Department of Chemical Engineering, McMaster University, Hamilton, ON L8S 4L7, Canada.
Pan S; Department of Chemical Engineering, McMaster University, Hamilton, ON L8S 4L7, Canada.
Durocher Y; National Research Council of Canada, Montreal, QC H4P 2R2, Canada; Département de biochimie et médecine moléculaire, Faculté de médecine, Université de Montréal, Montreal, QC H3C 3J7, Canada.
Ghosh R; Department of Chemical Engineering, McMaster University, Hamilton, ON L8S 4L7, Canada. Electronic address: .
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Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2023 Jan 15; Vol. 1215, pp. 123579. Date of Electronic Publication: 2022 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
Spike Glycoprotein, Coronavirus*/biosynthesis
Spike Glycoprotein, Coronavirus*/isolation & purification
Recombinant Proteins*/biosynthesis
Recombinant Proteins*/isolation & purification
COVID-19 Vaccines ; SARS-CoV-2/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Medium optimization for enhanced production of recombinant lignin peroxidase in Pichia pastoris.
Autorzy:
Biko OD; Department of Microbiology, Stellenbosch University, Private Bag X1, Stellenbosch, 7602, South Africa.
Viljoen-Bloom M; Department of Microbiology, Stellenbosch University, Private Bag X1, Stellenbosch, 7602, South Africa.
van Zyl WH; Department of Microbiology, Stellenbosch University, Private Bag X1, Stellenbosch, 7602, South Africa. .
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Źródło:
Biotechnology letters [Biotechnol Lett] 2023 Jan; Vol. 45 (1), pp. 105-113. Date of Electronic Publication: 2022 Nov 19.
Typ publikacji:
Journal Article
MeSH Terms:
Pichia*/growth & development
Pichia*/metabolism
Peroxidases*/biosynthesis
Peroxidases*/genetics
Recombinant Proteins*/biosynthesis
Recombinant Proteins*/genetics
Phanerochaete*/enzymology
Phanerochaete*/genetics
Fungal Proteins*/biosynthesis
Fungal Proteins*/genetics
Culture Media*/chemistry
Methanol/metabolism ; Sorbitol/metabolism
SCR Organism:
Komagataella pastoris; Komagataella phaffii
Czasopismo naukowe
Szczegóły
Tytuł:
Concentration-Dependent Efficacy of Recombinant Human Bone Morphogenetic Protein-2 Using a HA/β-TCP Hydrogel Carrier in a Mini-Pig Vertebral Oblique Lateral Interbody Fusion Model.
Autorzy:
Lee HY; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.
Kang JI; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.; Department of Neurosurgery, Yongin Severance Hospital, Yonsei University College of Medicine, 363, Yongin-si 16995, Republic of Korea.
Lee HL; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.
Hwang GY; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.
Kim KN; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.
Ha Y; Spine & Spinal Cord Institute, Department of Neurosurgery, College of Medicine, Yonsei University, Seoul 03722, Republic of Korea.; POSTECH Biotech Center, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jan 03; Vol. 24 (1). Date of Electronic Publication: 2023 Jan 03.
Typ publikacji:
Journal Article
MeSH Terms:
Bone Morphogenetic Protein 2*/therapeutic use
Recombinant Proteins*/therapeutic use
Spinal Fusion*/methods
Animals ; Humans ; Hydrogels ; Swine ; Swine, Miniature ; Transforming Growth Factor beta/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Survey of Anaphylaxis during Rasburicase Re-Administration in Patients with Hematological Malignancies Using a Japanese Claims Database.
Autorzy:
Kobayashi S; Department of Public Health and Epidemiology, Meiji Pharmaceutical University, Tokyo 204-8588, Japan.; Department of Pharmacy, Nissan Tamagawa Hospital, Tokyo 158-0095, Japan.
Yasu T; Pharmaceutical Education and Research Center, Department of Medicinal Therapy Research, Meiji Pharmaceutical University, Tokyo 204-8588, Japan.
Akazawa M; Department of Public Health and Epidemiology, Meiji Pharmaceutical University, Tokyo 204-8588, Japan.
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Źródło:
Current oncology (Toronto, Ont.) [Curr Oncol] 2022 Dec 14; Vol. 29 (12), pp. 9826-9832. Date of Electronic Publication: 2022 Dec 14.
Typ publikacji:
Multicenter Study; Journal Article
MeSH Terms:
Hematologic Neoplasms*/drug therapy
Tumor Lysis Syndrome*/complications
Tumor Lysis Syndrome*/drug therapy
Urate Oxidase*/administration & dosage
Urate Oxidase*/adverse effects
Recombinant Proteins*/administration & dosage
Recombinant Proteins*/therapeutic use
Anaphylaxis*/epidemiology
Anaphylaxis*/etiology
Humans ; East Asian People
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Metal-dependent glycosylation in recombinant metallothioneins.
Autorzy:
García-Risco M; Department of Chemistry, Universitat Autònoma de Barcelona, Cerdanyola del Vallès (E-08193), Spain. .
González A; Department of Inorganic Chemistry and Biotechnology Institute, University of Granada, Granada (E-18071), Spain. .
Calatayud S; Department of Genetics, Microbiology and Statistics, University of Barcelona, Barcelona (E-08028), Spain.
Lopez-Jaramillo FJ; Department of Organic Chemistry and Biotechnology Institute, University of Granada, Granada (E-18071), Spain.
Pedrini-Martha V; Institute of Zoology and Center of Molecular Biosciences, University of Innsbruck, Innsbruck (A-60210), Austria.
Albalat R; Department of Genetics, Microbiology and Statistics, University of Barcelona, Barcelona (E-08028), Spain.; Institut de Recerca de la Biodiversitat (IRBio), Universitat de Barcelona, Barcelona (E-08028), Spain.
Dallinger R; Institute of Zoology and Center of Molecular Biosciences, University of Innsbruck, Innsbruck (A-60210), Austria.
Dominguez-Vera JM; Department of Inorganic Chemistry and Biotechnology Institute, University of Granada, Granada (E-18071), Spain. .
Palacios Ò; Department of Chemistry, Universitat Autònoma de Barcelona, Cerdanyola del Vallès (E-08193), Spain. .
Capdevila M; Department of Chemistry, Universitat Autònoma de Barcelona, Cerdanyola del Vallès (E-08193), Spain. .
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Źródło:
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2022 Dec 13; Vol. 58 (99), pp. 13755-13758. Date of Electronic Publication: 2022 Dec 13.
Typ publikacji:
Journal Article
MeSH Terms:
Escherichia coli*/metabolism
Metallothionein*/chemistry
Metallothionein*/metabolism
Recombinant Proteins*/chemistry
Recombinant Proteins*/metabolism
Metals/metabolism ; Glycosylation
Czasopismo naukowe
Szczegóły
Tytuł:
Extracellular production of Ulp1 403-621 in leaky E. coli and its application in antimicrobial peptide production.
Autorzy:
Fu L; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Sun M; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Wen W; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China.
Dong N; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China. .
Li D; State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, People's Republic of China. .
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Źródło:
Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2022 Dec; Vol. 106 (23), pp. 7805-7817. Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Antimicrobial Peptides*
Escherichia coli*/metabolism
Recombinant Proteins*/biosynthesis
Recombinant Proteins*/genetics
Endopeptidases/genetics ; Endopeptidases/metabolism ; Glycine/metabolism ; Peptide Hydrolases/metabolism ; Ubiquitins/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study.
Autorzy:
Tang D; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.; Protein Sciences, Proteologix US Inc., Redwood Shores, California, USA.
Gunson J; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Tran E; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Lam C; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Shen A; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Snedecor B; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Barnard G; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
Misaghi S; Cell Culture and Bioprocess Operations Department, Genentech Inc., South San Francisco, California, USA.
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Źródło:
Biotechnology progress [Biotechnol Prog] 2022 Nov; Vol. 38 (6), pp. e3290. Date of Electronic Publication: 2022 Aug 16.
Typ publikacji:
Journal Article
MeSH Terms:
Immunoglobulin Fab Fragments*/biosynthesis
Immunoglobulin Fab Fragments*/genetics
Recombinant Proteins*/biosynthesis
Recombinant Proteins*/genetics
Animals ; Cricetinae ; CHO Cells ; Cricetulus ; Gene Dosage ; Transgenes
Czasopismo naukowe
Szczegóły
Tytuł:
Cell factory engineering: Challenges and opportunities for synthetic biology applications.
Autorzy:
Bachhav B; Department of Chemical and Biochemical Engineering, Rice University, Houston, Texas, USA.
de Rossi J; Systems, Synthetic, and Physical Biology, Rice University, Houston, Texas, USA.
Llanos CD; Systems, Synthetic, and Physical Biology, Rice University, Houston, Texas, USA.
Segatori L; Department of Chemical and Biochemical Engineering, Rice University, Houston, Texas, USA.; Systems, Synthetic, and Physical Biology, Rice University, Houston, Texas, USA.; Department of Bioengineering, Rice University, Houston, Texas, USA.; Department of Biosciences, Rice University, Houston, Texas, USA.
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Źródło:
Biotechnology and bioengineering [Biotechnol Bioeng] 2023 Sep; Vol. 120 (9), pp. 2441-2459. Date of Electronic Publication: 2023 Mar 11.
Typ publikacji:
Journal Article; Review; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms:
Synthetic Biology*
Cell Engineering*
Animals ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Protein Processing, Post-Translational ; Metabolic Engineering ; Mammals/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Novel expression system based on enhanced permeability of Vibrio natriegens cells induced by D,D- carboxypeptidase overexpression.
Autorzy:
Kormanová Ľ; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic. .
Levarski Z; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.; Science Park, Comenius University in Bratislava, Ilkovičova 8, Bratislava, 811 04, Slovak Republic.
Minich A; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.
Varga V; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.
Levarská L; Science Park, Comenius University in Bratislava, Ilkovičova 8, Bratislava, 811 04, Slovak Republic.
Struhárňanská E; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.
Turňa J; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.
Stuchlík S; Faculty of Natural Sciences, Comenius University in Bratislava, Ilkovičova 6, Bratislava, 811 04, Slovak Republic.
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Źródło:
World journal of microbiology & biotechnology [World J Microbiol Biotechnol] 2023 Aug 12; Vol. 39 (10), pp. 277. Date of Electronic Publication: 2023 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Serine-Type D-Ala-D-Ala Carboxypeptidase*/metabolism
Vibrio*/metabolism
Permeability ; Carboxypeptidases/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism
SCR Organism:
Vibrio natriegens
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 145369

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