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Tytuł :
Mutation-specific pathophysiological mechanisms define different neurodevelopmental disorders associated with SATB1 dysfunction.
Autorzy :
den Hoed J; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, the Netherlands; International Max Planck Research School for Language Sciences, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, the Netherlands.
de Boer E; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands.
Voisin N; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
Dingemans AJM; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands.
Guex N; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland; Bioinformatics Competence Center, University of Lausanne, 1015 Lausanne, Switzerland.
Wiel L; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands; Center for Molecular and Biomolecular Informatics of the Radboudumc, 6500 HB Nijmegen, the Netherlands.
Nellaker C; Nuffield Department of Women's and Reproductive Health, University of Oxford, Women's Centre, John Radcliffe Hospital, Oxford OX3 9DU, UK; Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford OX3 7DQ, UK; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7LF, UK.
Amudhavalli SM; University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA; Department of Pediatrics, Division of Clinical Genetics, Children's Mercy Hospital, Kansas City, MO 64108, USA.
Banka S; Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Health Innovation Manchester, Manchester M13 9WL, UK.
Bena FS; Service of Genetic Medicine, University Hospitals of Geneva, 1205 Geneva, Switzerland.
Ben-Zeev B; Edmomd and Lilly Safra Pediatric Hospital, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.
Bonagura VR; Institute of Molecular Medicine, Feinstein Institutes for Medical Research, Manhasset, NY 11030, USA; Pediatrics and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA.
Bruel AL; UMR1231-Inserm, Génétique des Anomalies du développement, Université de Bourgogne Franche-Comté, 21070 Dijon, France; Laboratoire de Génétique chromosomique et moléculaire, UF6254 Innovation en diagnostic génomique des maladies rares, Centre Hospitalier Universitaire de Dijon, 21070 Dijon, France.
Brunet T; Institute of Human Genetics, Technical University of Munich, 81675 Munich, Germany.
Brunner HG; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands; Maastricht University Medical Center, Department of Clinical Genetics, GROW School for Oncology and Developmental Biology, and MHeNS School for Mental health and Neuroscience, PO Box 5800, 6202AZ Maastricht, the Netherlands.
Chew HB; Department of Genetics, Kuala Lumpur Hospital, Jalan Pahang, 50586 Kuala Lumpur, Malaysia.
Chrast J; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
Cimbalistienė L; Department of Human and Medical Genetics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Coon H; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Délot EC; Center for Genetic Medicine Research, Children's National Hospital, Children's Research Institute and Department of Genomics and Precision Medicine, George Washington University, Washington, DC 20010, USA.
Démurger F; Department of clinical genetics, Vannes hospital, 56017 Vannes, France.
Denommé-Pichon AS; UMR1231-Inserm, Génétique des Anomalies du développement, Université de Bourgogne Franche-Comté, 21070 Dijon, France; Laboratoire de Génétique chromosomique et moléculaire, UF6254 Innovation en diagnostic génomique des maladies rares, Centre Hospitalier Universitaire de Dijon, 21070 Dijon, France.
Depienne C; Institute of Human Genetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Donnai D; Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK; Manchester Centre for Genomic Medicine, St Mary's Hospital, Manchester University NHS Foundation Trust, Health Innovation Manchester, Manchester M13 9WL, UK.
Dyment DA; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada.
Elpeleg O; Department of Genetics, Hadassah Medical Center, Hebrew University Medical Center, 91120 Jerusalem, Israel.
Faivre L; UMR1231-Inserm, Génétique des Anomalies du développement, Université de Bourgogne Franche-Comté, 21070 Dijon, France; Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs de l'Interrégion Est, Centre Hospitalier Universitaire Dijon, 21079 Dijon, France; Fédération Hospitalo-Universitaire Médecine Translationnelle et Anomalies du Développement (TRANSLAD), Centre Hospitalier Universitaire Dijon, 21079 Dijon, France.
Gilissen C; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6500 HB Nijmegen, the Netherlands.
Granger L; Department of Rehabilitation and Development, Randall Children's Hospital at Legacy Emanuel Medical Center, Portland, OR 97227, USA.
Haber B; Division of Child Neurology and Inherited Metabolic Diseases, Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Hachiya Y; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo 183-0042, Japan.
Abedi YH; Division of Allergy and Immunology, Northwell Health, Great Neck, NY 11021, USA; Departments of Medicine and Pediatrics, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549, USA.
Hanebeck J; Division of Child Neurology and Inherited Metabolic Diseases, Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Hehir-Kwa JY; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, the Netherlands.
Horist B; Pediatrics & Genetics, Alpharetta, GA 30005, USA.
Itai T; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.
Jackson A; Manchester Centre for Genomic Medicine, Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PL, UK.
Jewell R; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds LS7 4SA, UK.
Jones KL; Division of Medical Genetics & Metabolism, Children's Hospital of The King's Daughters, Norfolk, VA 23507, USA; Department of Pediatrics, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Joss S; West of Scotland Centre for Genomic Medicine, Queen Elizabeth University Hospital, Glasgow G51 4TF, UK.
Kashii H; Department of Neuropediatrics, Tokyo Metropolitan Neurological Hospital, Fuchu, Tokyo 183-0042, Japan.
Kato M; Department of Pediatrics, Showa University School of Medicine, Shinagawa-ku, Tokyo 142-8666, Japan.
Kattentidt-Mouravieva AA; Zuidwester, 3240AA Middelharnis, the Netherlands.
Kok F; Mendelics Genomic Analysis, Sao Paulo, SP 04013-000, Brazil; University of Sao Paulo, School of Medicine, Sao Paulo, SP 01246-903, Brazil.
Kotzaeridou U; Division of Child Neurology and Inherited Metabolic Diseases, Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Krishnamurthy V; Pediatrics & Genetics, Alpharetta, GA 30005, USA.
Kučinskas V; Department of Human and Medical Genetics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Kuechler A; Institute of Human Genetics, University Hospital Essen, University of Duisburg-Essen, 45147 Essen, Germany.
Lavillaureix A; CHU Rennes, Univ Rennes, CNRS, IGDR, Service de Génétique Clinique, Centre de Référence Maladies Rares CLAD-Ouest, ERN ITHACA, Hôpital Sud, 35033 Rennes, France.
Liu P; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Baylor Genetics, Houston, TX 77021, USA.
Manwaring L; Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine, St. Louis, MO 63110-1093, USA.
Matsumoto N; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.
Mazel B; Centre de Génétique et Centre de Référence Anomalies du Développement et Syndromes Malformatifs de l'Interrégion Est, Centre Hospitalier Universitaire Dijon, 21079 Dijon, France.
McWalter K; GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA.
Meiner V; Department of Genetics, Hadassah Medical Center, Hebrew University Medical Center, 91120 Jerusalem, Israel.
Mikati MA; Division of Pediatric Neurology, Duke University Medical Center, Durham, NC 27710, USA.
Miyatake S; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.
Mizuguchi T; Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa 236-0004, Japan.
Moey LH; Department of Genetics, Penang General Hospital, Jalan Residensi, 10990 Georgetown, Penang, Malaysia.
Mohammed S; Clinical Genetics, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.
Mor-Shaked H; Department of Genetics, Hadassah Medical Center, Hebrew University Medical Center, 91120 Jerusalem, Israel.
Mountford H; Department of Biological and Medical Sciences, Headington Campus, Oxford Brookes University, Oxford OX3 0BP, UK.
Newbury-Ecob R; Clinical Genetics, St Michael's Hospital Bristol, University Hospitals Bristol NHS Foundation Trust, Bristol BS2 8EG, UK.
Odent S; CHU Rennes, Univ Rennes, CNRS, IGDR, Service de Génétique Clinique, Centre de Référence Maladies Rares CLAD-Ouest, ERN ITHACA, Hôpital Sud, 35033 Rennes, France.
Orec L; Division of Child Neurology and Inherited Metabolic Diseases, Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Osmond M; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada.
Palculict TB; GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA.
Parker M; Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield S5 7AU, UK.
Petersen AK; Department of Rehabilitation and Development, Randall Children's Hospital at Legacy Emanuel Medical Center, Portland, OR 97227, USA.
Pfundt R; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands.
Preikšaitienė E; Department of Human and Medical Genetics, Institute of Biomedical Sciences, Faculty of Medicine, Vilnius University, 08661 Vilnius, Lithuania.
Radtke K; Clinical Genomics Department, Ambry Genetics, Aliso Viejo, CA 92656, USA.
Ranza E; Service of Genetic Medicine, University Hospitals of Geneva, 1205 Geneva, Switzerland; Medigenome, Swiss Institute of Genomic Medicine, 1207 Geneva, Switzerland.
Rosenfeld JA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
Santiago-Sim T; GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA.
Schwager C; University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA; Department of Pediatrics, Division of Clinical Genetics, Children's Mercy Hospital, Kansas City, MO 64108, USA.
Sinnema M; Department of Clinical Genetics, Maastricht University Medical Center+, azM, 6202 AZ Maastricht, the Netherlands; Department of Genetics and Cell Biology, Faculty of Health Medicine Life Sciences, Maastricht University Medical Center+, Maastricht University, 6229 ER Maastricht, the Netherlands.
Snijders Blok L; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, the Netherlands; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands.
Spillmann RC; Department of Pediatrics, Division of Medical Genetics, Duke University Medical Center, Durham, NC 27713, USA.
Stegmann APA; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Department of Clinical Genetics, Maastricht University Medical Center+, azM, 6202 AZ Maastricht, the Netherlands.
Thiffault I; University of Missouri-Kansas City School of Medicine, Kansas City, MO 64108, USA; Center for Pediatric Genomic Medicine, Children's Mercy Hospital, Kansas City, MO 64108, USA; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, Kansas City, MO 64108, USA.
Tran L; Division of Pediatric Neurology, Duke University Medical Center, Durham, NC 27710, USA.
Vaknin-Dembinsky A; Department of Neurology and Laboratory of Neuroimmunology, The Agnes Ginges Center for Neurogenetics, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, 91120 Jerusalem, Israel.
Vedovato-Dos-Santos JH; Mendelics Genomic Analysis, Sao Paulo, SP 04013-000, Brazil.
Schrier Vergano SA; Division of Medical Genetics & Metabolism, Children's Hospital of The King's Daughters, Norfolk, VA 23507, USA.
Vilain E; Center for Genetic Medicine Research, Children's National Hospital, Children's Research Institute and Department of Genomics and Precision Medicine, George Washington University, Washington, DC 20010, USA.
Vitobello A; UMR1231-Inserm, Génétique des Anomalies du développement, Université de Bourgogne Franche-Comté, 21070 Dijon, France; Laboratoire de Génétique chromosomique et moléculaire, UF6254 Innovation en diagnostic génomique des maladies rares, Centre Hospitalier Universitaire de Dijon, 21070 Dijon, France.
Wagner M; Institute of Human Genetics, Technical University of Munich, 81675 Munich, Germany; Institute of Neurogenomics, Helmholtz Zentrum München, 85764 Munich, Germany.
Waheeb A; Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON K1H 5B2, Canada; Department of Genetics, Children's Hospital of Eastern Ontario, Ottawa, ON K1H 8L1, Canada.
Willing M; Department of Pediatrics, Division of Genetics and Genomic Medicine, Washington University School of Medicine, St. Louis, MO 63110-1093, USA.
Zuccarelli B; The University of Kansas School of Medicine Salina Campus, Salina, KS 67401, USA.
Kini U; Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford OX3 7LE, UK.
Newbury DF; Department of Biological and Medical Sciences, Headington Campus, Oxford Brookes University, Oxford OX3 0BP, UK.
Kleefstra T; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands.
Reymond A; Center for Integrative Genomics, University of Lausanne, 1015 Lausanne, Switzerland.
Fisher SE; Language and Genetics Department, Max Planck Institute for Psycholinguistics, 6500 AH Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands. Electronic address: .
Vissers LELM; Department of Human Genetics, Radboudumc, 6500 HB Nijmegen, the Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University, 6500 GL Nijmegen, the Netherlands.
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Corporate Authors :
DDD Study; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
Źródło :
American journal of human genetics [Am J Hum Genet] 2021 Feb 04; Vol. 108 (2), pp. 346-356. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mutation*
Matrix Attachment Region Binding Proteins/*genetics
Neurodevelopmental Disorders/*genetics
Chromatin/metabolism ; Female ; Genetic Association Studies ; Haploinsufficiency ; Humans ; Male ; Matrix Attachment Region Binding Proteins/chemistry ; Matrix Attachment Region Binding Proteins/metabolism ; Models, Molecular ; Mutation, Missense ; Protein Binding ; Protein Domains ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Subcircuits of Deep and Superficial CA1 Place Cells Support Efficient Spatial Coding across Heterogeneous Environments.
Autorzy :
Sharif F; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Tayebi B; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA.
Buzsáki G; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA; Center for Neural Science, New York University, New York, NY 10003, USA; Department of Neurology, Langone Medical Center, New York University, New York, NY 10016, USA.
Royer S; Center for Functional Connectomics, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea; Division of Bio-Medical Science and Technology, KIST School, Korea University of Science and Technology, Seoul 02792, Republic of Korea. Electronic address: .
Fernandez-Ruiz A; Neuroscience Institute, New York University, Langone Medical Center, New York, NY 10016, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2021 Jan 20; Vol. 109 (2), pp. 363-376.e6. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Environment Design*
CA1 Region, Hippocampal/*physiology
Nerve Net/*physiology
Place Cells/*physiology
Space Perception/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; Electrodes, Implanted ; Male ; Maze Learning/physiology ; Mice ; Mice, Inbred C57BL ; Nerve Net/cytology ; Rats ; Rats, Long-Evans
Czasopismo naukowe
Tytuł :
Collaural Sinus: A Case Report.
Autorzy :
Huq AZ; Dr AHM Zahurul Huq, Professor Otolaryngology-Head & Neck Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh; E-mail: .
Parvez SR
Talukder HR
Bhowmik B
Islam MD
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Źródło :
Mymensingh medical journal : MMJ [Mymensingh Med J] 2021 Jan; Vol. 30 (1), pp. 233-237.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Branchial Region*
Paranasal Sinuses*
Adult ; Bangladesh ; Child ; Ear Canal ; Female ; Humans ; Magnetic Resonance Imaging
Czasopismo naukowe
Tytuł :
Chronic intractable lumbosacral radicular pain, is there a remedy? Pulsed radiofrequency treatment and volumetric modifications of the lumbar dorsal root ganglia.
Autorzy :
Tortora F; Dipartimento di Medicina di Precisione, Università degli Studi della Campania Luigi Vanvitelli, Servizio di Neuroradiologia, PO CTO, Viale Colli Aminei, 21, 80131, Naples, Italy.
Negro A; Università degli Studi della Campania Luigi Vanvitelli, Servizio di Neuroradiologia, PO CTO, Viale Colli Aminei, 21, 80131, Naples, Italy. .; M.D. UOC Neuroradiologia PO Ospedale del Mare, ASL NA1, Via Enrico Russo, 80147, Naples, Italy. .
Russo C; Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II, Via Sergio Pansini, 5, 80131, Naples, Italy.
Cirillo S; Dipartimento di Internistica Clinica e Sperimentale Flaviano Magrassi, Università degli Studi della Campania Luigi Vanvitelli, Servizio di Neuroradiologia, PO CTO, Viale Colli Aminei, 21, 80131, Naples, Italy.
Caranci F; Dipartimento di Medicina e Scienze per la Salute, Università degli Studi del Molise, Via G. Paolo II contrada 'Tappino', 86100, Campobasso, Italy.
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Źródło :
La Radiologia medica [Radiol Med] 2021 Jan; Vol. 126 (1), pp. 124-132. Date of Electronic Publication: 2020 May 04.
Typ publikacji :
Journal Article
MeSH Terms :
Ganglia, Spinal*
Lumbosacral Region*
Radiography, Interventional*
Tomography, X-Ray Computed*
Low Back Pain/*therapy
Pulsed Radiofrequency Treatment/*methods
Radiculopathy/*therapy
Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Longitudinal Studies ; Low Back Pain/diagnostic imaging ; Male ; Middle Aged ; Pain Management/methods ; Prospective Studies ; Radiculopathy/diagnostic imaging
Czasopismo naukowe
Tytuł :
Spinal Manipulation for Subacute and Chronic Lumbar Radiculopathy: A Randomized Controlled Trial.
Autorzy :
Ghasabmahaleh SH; Aja University of Medical Sciences, Western Fatemi, Tehran.
Rezasoltani Z; Aja University of Medical Sciences, Western Fatemi, Tehran.
Dadarkhah A; Aja University of Medical Sciences, Western Fatemi, Tehran.
Hamidipanah S; Aja University of Medical Sciences, Western Fatemi, Tehran.
Mofrad RK; Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Najafi S; Aja University of Medical Sciences, Western Fatemi, Tehran. Electronic address: .
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Źródło :
The American journal of medicine [Am J Med] 2021 Jan; Vol. 134 (1), pp. 135-141. Date of Electronic Publication: 2020 Sep 13.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Lumbosacral Region*
Manipulation, Spinal/*standards
Radiculopathy/*therapy
Adult ; Analysis of Variance ; Female ; Humans ; Iran ; Low Back Pain/therapy ; Male ; Manipulation, Spinal/methods ; Manipulation, Spinal/statistics & numerical data ; Middle Aged ; Pain Management/methods ; Pain Measurement/methods ; Radiculopathy/complications ; Surveys and Questionnaires ; Treatment Outcome ; Visual Analog Scale
Czasopismo naukowe
Tytuł :
Global Investigation of Immune Repertoire Suggests Kawasaki Disease Has Infectious Cause.
Autorzy :
Kuo HC; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital.; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
Pan CT; Institute of Bioinformatics and Systems Biology, National Chiao Tung University.
Huang YH; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital.; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
Huang FC; Kawasaki Disease Center, Kaohsiung Chang Gung Memorial Hospital.; Department of Pediatrics, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
Lin YS; Institute of Bioinformatics and Systems Biology, National Chiao Tung University.; Department of Biological Science and Technology, National Chiao Tung University.
Li SC; Genomics and Proteomics Core Laboratory, Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
Huang LH; Genomics and Proteomics Core Laboratory, Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine.
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Źródło :
Circulation journal : official journal of the Japanese Circulation Society [Circ J] 2019 Sep 25; Vol. 83 (10), pp. 2070-2078. Date of Electronic Publication: 2019 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibody Diversity*/genetics
Immunoglobulin Variable Region*
V(D)J Recombination*
Autoimmune Diseases/*immunology
B-Lymphocytes/*immunology
Immunoglobulins/*immunology
Mucocutaneous Lymph Node Syndrome/*immunology
Respiratory Tract Infections/*immunology
Autoimmune Diseases/diagnosis ; Autoimmune Diseases/genetics ; Case-Control Studies ; Complementarity Determining Regions ; Female ; Humans ; Immunoglobulin Class Switching ; Immunoglobulin Joining Region ; Immunoglobulins/genetics ; Male ; Mucocutaneous Lymph Node Syndrome/diagnosis ; Mucocutaneous Lymph Node Syndrome/genetics ; Respiratory Tract Infections/diagnosis ; Respiratory Tract Infections/genetics ; Risk Factors
Czasopismo naukowe
Tytuł :
DG-CA3 circuitry mediates hippocampal representations of latent information.
Autorzy :
Keinath AT; Department of Psychiatry, Douglas Hospital Research Centre, McGill University, 6875 Boulevard LaSalle, Verdun, QC, H4H 1R3, Canada. .
Nieto-Posadas A; Department of Psychiatry, Douglas Hospital Research Centre, McGill University, 6875 Boulevard LaSalle, Verdun, QC, H4H 1R3, Canada.
Robinson JC; Department of Psychological and Brain Sciences, Rajen Kilachand Center for Integrated Life Sciences and Engineering, Boston University, 610 Commonwealth Avenue, Boston, MA, 02215, USA.
Brandon MP; Department of Psychiatry, Douglas Hospital Research Centre, McGill University, 6875 Boulevard LaSalle, Verdun, QC, H4H 1R3, Canada. .; Integrated Program in Neuroscience, Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, QC, H3A 2B4, Canada. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 15; Vol. 11 (1), pp. 3026. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA3 Region, Hippocampal/*physiology
Dentate Gyrus/*physiology
Animals ; CA1 Region, Hippocampal/physiology ; Male ; Memory ; Mice, Inbred C57BL ; Models, Neurological ; Pattern Recognition, Physiological
Czasopismo naukowe
Tytuł :
Differential Emergence and Stability of Sensory and Temporal Representations in Context-Specific Hippocampal Sequences.
Autorzy :
Taxidis J; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Integrative Center for Learning and Memory, Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: .
Pnevmatikakis EA; Center for Computational Mathematics, Flatiron Institute, New York, NY, USA.
Dorian CC; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Mylavarapu AL; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Arora JS; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Samadian KD; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Hoffberg EA; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Golshani P; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA; Integrative Center for Learning and Memory, Brain Research Institute, University of California, Los Angeles, Los Angeles, CA, USA; Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, Los Angeles, CA, USA; West Los Angeles Veteran Affairs Medical Center, Los Angeles, CA, USA; Intellectual and Developmental Disabilities Research Center, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 984-998.e9. Date of Electronic Publication: 2020 Sep 18.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cues*
Odorants*
CA1 Region, Hippocampal/*physiology
Memory, Short-Term/*physiology
Smell/*physiology
Action Potentials ; Animals ; CA1 Region, Hippocampal/chemistry ; CA1 Region, Hippocampal/cytology ; Male ; Memory, Short-Term/drug effects ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Transgenic ; Microscopy, Fluorescence, Multiphoton/methods ; Smell/drug effects ; Time Factors
Czasopismo naukowe
Tytuł :
Large-Scale 3D Two-Photon Imaging of Molecularly Identified CA1 Interneuron Dynamics in Behaving Mice.
Autorzy :
Geiller T; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Vancura B; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Terada S; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Troullinou E; Institute of Computer Science, Foundation for Research and Technology Hellas, Heraklion, Crete 70013, Greece; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Chavlis S; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete 70013, Greece.
Tsagkatakis G; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Tsakalides P; Institute of Computer Science, Foundation for Research and Technology Hellas, Heraklion, Crete 70013, Greece; Department of Computer Science, University of Crete, Heraklion, Crete 70013, Greece.
Ócsai K; Faculty of Information Technology, Pázmány Péter University, Budapest, Hungary.
Poirazi P; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas (FORTH), Heraklion, Crete 70013, Greece.
Rózsa BJ; Faculty of Information Technology, Pázmány Péter University, Budapest, Hungary; Laboratory of 3D Functional Network and Dendritic Imaging, Institute of Experimental Medicine, Hungarian Academy of Sciences, Eötvös Loránd Research Network, Budapest, Hungary.
Losonczy A; Department of Neuroscience, Columbia University, New York, NY, USA; Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA; The Kavli Institute for Brain Science, Columbia University, New York, NY, USA. Electronic address: .
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Źródło :
Neuron [Neuron] 2020 Dec 09; Vol. 108 (5), pp. 968-983.e9. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal/*cytology
CA1 Region, Hippocampal/*diagnostic imaging
Imaging, Three-Dimensional/*methods
Interneurons/*ultrastructure
Microscopy, Fluorescence, Multiphoton/*methods
Animals ; CA1 Region, Hippocampal/chemistry ; Calcium/analysis ; Calcium/metabolism ; Female ; Interneurons/chemistry ; Male ; Mice ; Mice, Transgenic ; Microscopy, Confocal/methods
Czasopismo naukowe
Tytuł :
Hippocampal CA2 sharp-wave ripples reactivate and promote social memory.
Autorzy :
Oliva A; Department of Neuroscience, The Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA. .
Fernández-Ruiz A; New York University Neuroscience Institute, New York University, New York, NY, USA.
Leroy F; Department of Neuroscience, The Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA.
Siegelbaum SA; Department of Neuroscience, The Kavli Institute for Brain Science, Mortimer B. Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY, USA. .; Department of Pharmacology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. .
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Źródło :
Nature [Nature] 2020 Nov; Vol. 587 (7833), pp. 264-269. Date of Electronic Publication: 2020 Sep 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Social Interaction*
CA2 Region, Hippocampal/*physiology
Memory/*physiology
Sleep/*physiology
Animals ; CA2 Region, Hippocampal/anatomy & histology ; CA2 Region, Hippocampal/cytology ; Male ; Memory Consolidation/physiology ; Mental Recall/physiology ; Mice ; Mice, Inbred C57BL ; Optogenetics ; Pyramidal Cells/physiology
Czasopismo naukowe
Tytuł :
Conformational changes in a Vernier zone region: Implications for antibody dual specificity.
Autorzy :
Arslan M; Izmir Biomedicine and Genome Center, Izmir, Turkey.; Izmir Biomedicine and Genome Institute, Dokuz Eylül University, Izmir, Turkey.
Karadag D; Izmir Biomedicine and Genome Center, Izmir, Turkey.
Kalyoncu S; Izmir Biomedicine and Genome Center, Izmir, Turkey.
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Źródło :
Proteins [Proteins] 2020 Nov; Vol. 88 (11), pp. 1447-1457. Date of Electronic Publication: 2020 Jul 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Bispecific/*chemistry
Antigens/*chemistry
Antineoplastic Agents, Immunological/*chemistry
Immunoglobulin Variable Region/*chemistry
Receptor, ErbB-2/*chemistry
Vascular Endothelial Growth Factor A/*chemistry
Amino Acid Sequence ; Antibodies, Bispecific/genetics ; Antibodies, Bispecific/metabolism ; Antibody Affinity ; Antibody Specificity ; Antigens/genetics ; Antigens/immunology ; Antineoplastic Agents, Immunological/metabolism ; Binding Sites ; Binding Sites, Antibody/genetics ; Humans ; Immunoglobulin Variable Region/genetics ; Immunoglobulin Variable Region/metabolism ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Engineering/methods ; Protein Interaction Domains and Motifs ; Receptor, ErbB-2/antagonists & inhibitors ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/immunology ; Sequence Alignment ; Structural Homology, Protein ; Thermodynamics ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/immunology
Czasopismo naukowe
Tytuł :
High Potency of a Bivalent Human V H Domain in SARS-CoV-2 Animal Models.
Autorzy :
Li W; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA. Electronic address: .
Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center, Chapel Hill, NC 27599, USA.
Kulkarni SS; Vaccine and Infectious Disease Organization-International Vaccine Centre, and the Department of Veterinary Microbiology, University of Saskatchewan, 117 Veterinary Road, Saskatoon, SK S7N 5E3, Canada.
Liu X; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA.
Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center, Chapel Hill, NC 27599, USA.
Chen C; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA.
Sun Z; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA.
Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center, Chapel Hill, NC 27599, USA.
Drelich A; Department of Microbiology and Immunology, Centers for Biodefense and Emerging Diseases, Galveston National Laboratory, 301 University Blvd., Galveston, TX 77550, USA.
Zhang L; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA.
Ura ML; Abound Bio, 1401 Forbes Ave., Pittsburgh, PA 15219, USA.
Berezuk A; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Chittori S; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Leopold K; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Mannar D; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Srivastava SS; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Zhu X; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Peterson EC; Abound Bio, 1401 Forbes Ave., Pittsburgh, PA 15219, USA.
Tseng CT; Department of Microbiology and Immunology, Centers for Biodefense and Emerging Diseases, Galveston National Laboratory, 301 University Blvd., Galveston, TX 77550, USA.
Mellors JW; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA; Abound Bio, 1401 Forbes Ave., Pittsburgh, PA 15219, USA.
Falzarano D; Vaccine and Infectious Disease Organization-International Vaccine Centre, and the Department of Veterinary Microbiology, University of Saskatchewan, 117 Veterinary Road, Saskatoon, SK S7N 5E3, Canada.
Subramaniam S; Department of Biochemistry and Molecular Biology, University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver, BC V6T 1Z3, Canada.
Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, 135 Dauer Drive, 3109 Michael Hooker Research Center, Chapel Hill, NC 27599, USA.
Dimitrov DS; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, University of Pittsburgh Medical School, 3550 Terrace St., Pittsburgh, PA 15261, USA; Abound Bio, 1401 Forbes Ave., Pittsburgh, PA 15219, USA. Electronic address: .
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Źródło :
Cell [Cell] 2020 Oct 15; Vol. 183 (2), pp. 429-441.e16. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Peptide Library*
Coronavirus Infections/*drug therapy
Immunoglobulin Heavy Chains/*administration & dosage
Immunoglobulin Variable Region/*administration & dosage
Pneumonia, Viral/*drug therapy
Angiotensin-Converting Enzyme 2 ; Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Neutralizing/ultrastructure ; Antibodies, Viral/administration & dosage ; Antibodies, Viral/chemistry ; Antibodies, Viral/immunology ; Antibodies, Viral/ultrastructure ; Antibody Affinity ; COVID-19 ; Cricetinae ; Female ; Humans ; Immunoglobulin Fc Fragments/immunology ; Immunoglobulin Heavy Chains/chemistry ; Immunoglobulin Heavy Chains/immunology ; Immunoglobulin Heavy Chains/ultrastructure ; Immunoglobulin Variable Region/chemistry ; Immunoglobulin Variable Region/immunology ; Immunoglobulin Variable Region/ultrastructure ; Mice ; Mice, Inbred BALB C ; Mutation ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Protein Domains ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Spike Glycoprotein, Coronavirus/ultrastructure
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Sacrococcygeal teratoma with intraspinal extension: A case series and review of literature.
Autorzy :
Seilern Und Aspang J; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH.
Burnand KM; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH.
Ong H; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH.
Cross K; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH.
Thompson D; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH.
Giuliani S; Great Ormond Street Hospital for Children, Department of Paediatric Surgery-Specialist Neonatal and Paediatric Surgery, NHS Foundation Trust, Great Ormond Street, London WC1N 3JH. Electronic address: .
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Źródło :
Journal of pediatric surgery [J Pediatr Surg] 2020 Oct; Vol. 55 (10), pp. 2022-2025. Date of Electronic Publication: 2020 Feb 15.
Typ publikacji :
Case Reports; Journal Article; Review
MeSH Terms :
Sacrococcygeal Region*/diagnostic imaging
Sacrococcygeal Region*/pathology
Sacrococcygeal Region*/surgery
Spinal Neoplasms*/diagnostic imaging
Spinal Neoplasms*/pathology
Spinal Neoplasms*/surgery
Teratoma*/diagnostic imaging
Teratoma*/pathology
Teratoma*/surgery
Coccyx/diagnostic imaging ; Coccyx/pathology ; Coccyx/surgery ; Humans ; Infant ; Magnetic Resonance Imaging ; Sacrum/diagnostic imaging ; Sacrum/pathology ; Sacrum/surgery
Czasopismo naukowe
Tytuł :
Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association.
Autorzy :
Zhou M; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Kuruvilla L; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.
Shi X; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.
Viviano S; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.
Ahearn IM; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Amendola CR; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Su W; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Badri S; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Mahaffey J; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Fehrenbacher N; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Skok J; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016.
Schlessinger J; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.
Turk BE; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.
Calderwood DA; Department of Pharmacology, Yale School of Medicine, New Haven, CT 06510.; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510.
Philips MR; Perlmutter Cancer Center, NYU Langone Health, New York, NY 10016; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 15; Vol. 117 (50), pp. 31914-31922. Date of Electronic Publication: 2020 Nov 30.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Membrane/*metabolism
Dimethylallyltranstransferase/*metabolism
Matrix Attachment Region Binding Proteins/*metabolism
Neoplasms/*pathology
Nuclear Matrix-Associated Proteins/*metabolism
Proto-Oncogene Proteins p21(ras)/*metabolism
Receptors, Estrogen/*metabolism
Alkyl and Aryl Transferases/genetics ; Alkyl and Aryl Transferases/metabolism ; CRISPR-Cas Systems/genetics ; Computational Biology ; Datasets as Topic ; Gene Knockdown Techniques ; Humans ; Matrix Attachment Region Binding Proteins/genetics ; Neoplasms/genetics ; Nuclear Matrix-Associated Proteins/genetics ; Protein Prenylation ; Protein Subunits/metabolism ; Proto-Oncogene Proteins p21(ras)/genetics ; Receptors, Estrogen/genetics
Czasopismo naukowe
Tytuł :
[Exploration of the pathogenesis for a SRY-negative male with 46,XX disorder of sex development].
Autorzy :
Liu A; Department of Genetics Testing, Linyi People's Hospital, Linyi, Shandong 276003, China. .
Zhang L
Xu H
Chong B
Liu X
Li L
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Źródło :
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics [Zhonghua Yi Xue Yi Chuan Xue Za Zhi] 2020 Dec 10; Vol. 37 (12), pp. 1403-1406.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Disorders of Sex Development*/genetics
Sex-Determining Region Y Protein*/genetics
Female ; Humans ; Male ; Mutation/genetics ; Regulatory Sequences, Nucleic Acid/genetics ; Testis ; Whole Exome Sequencing
Czasopismo naukowe
Tytuł :
Patient journey following lumbar spinal fusion surgery (FuJourn): A multicentre exploration of the immediate post-operative period using qualitative patient diaries.
Autorzy :
Rushton A; School of Physical Therapy, Faculty of Health Sciences, Western University, London, Ontario, Canada.; Centre of Precision Rehabilitation for Spinal Pain, School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Jadhakhan F; Centre of Precision Rehabilitation for Spinal Pain, School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Masson A; Centre of Precision Rehabilitation for Spinal Pain, School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Athey V; Centre of Precision Rehabilitation for Spinal Pain, School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Staal JB; Radboud Institute for Health Sciences, IQ Healthcare, Radboud University Medical Centre, Nijmegen, The Netherlands.
Verra ML; Department of Physiotherapy, Bern University Hospital, Insel Group, Bern, Switzerland.
Emms A; Department of Physiotherapy, The Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham, United Kingdom.
Reddington M; Department of Physiotherapy, Sheffield Teaching Hospitals NHS Foundation Trust, Northern General Hospital, Sheffield, United Kingdom.
Cole A; Department of Orthopaedics & Trauma, Sheffield Children's Hospital NHS Foundation Trust, Sheffield, United Kingdom.
Willems PC; Maastricht University Medical Centre, Maastricht, The Netherlands.
Benneker L; Department of Orthopaedic Surgery Inselspital, University of Bern, Bern, Switzerland.
Heneghan NR; Centre of Precision Rehabilitation for Spinal Pain, School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Soundy A; School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom.
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Źródło :
PloS one [PLoS One] 2020 Dec 01; Vol. 15 (12), pp. e0241931. Date of Electronic Publication: 2020 Dec 01 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Back Pain/*surgery
Lumbosacral Region/*surgery
Neurodegenerative Diseases/*surgery
Spinal Fusion/*methods
Back Pain/physiopathology ; Female ; Humans ; Leg/physiopathology ; Leg/surgery ; Lumbar Vertebrae/pathology ; Lumbar Vertebrae/surgery ; Lumbosacral Region/pathology ; Male ; Middle Aged ; Neurodegenerative Diseases/physiopathology ; Postoperative Period ; Spinal Fusion/adverse effects ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Autorzy :
Xie W; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.
Sowemimo I; Institute of Molecular Biotechnology, Vienna BioCenter, 1030 Vienna, Austria.
Hayashi R; Department of Genome Sciences, The John Curtin School of Medical Research, Australian National University, Canberra 2601, Australia.
Wang J; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065.
Burkard TR; Institute of Molecular Biotechnology, Vienna BioCenter, 1030 Vienna, Austria.
Brennecke J; Institute of Molecular Biotechnology, Vienna BioCenter, 1030 Vienna, Austria; .
Ameres SL; Institute of Molecular Biotechnology, Vienna BioCenter, 1030 Vienna, Austria; .; Max Perutz Labs, University of Vienna, Vienna BioCenter, 1030 Vienna, Austria.
Patel DJ; Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 01; Vol. 117 (48), pp. 30370-30379. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
3' Flanking Region*
RNA Processing, Post-Transcriptional*
Structure-Activity Relationship*
Drosophila Proteins/*chemistry
Exoribonucleases/*chemistry
MicroRNAs/*chemistry
MicroRNAs/*genetics
Animals ; Argonaute Proteins/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster ; Exoribonucleases/metabolism ; MicroRNAs/metabolism ; Models, Biological ; Models, Molecular ; Molecular Conformation ; Mutation ; Protein Binding ; Protein Interaction Domains and Motifs ; RNA-Binding Proteins/chemistry ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Tytuł :
Lactate induces synapse-specific potentiation on CA3 pyramidal cells of rat hippocampus.
Autorzy :
Herrera-López G; Departamento de Farmacobiología, Cinvestav Sede Sur, México City, México.
Griego E; Departamento de Farmacobiología, Cinvestav Sede Sur, México City, México.
Galván EJ; Departamento de Farmacobiología, Cinvestav Sede Sur, México City, México.
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Źródło :
PloS one [PLoS One] 2020 Nov 12; Vol. 15 (11), pp. e0242309. Date of Electronic Publication: 2020 Nov 12 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA3 Region, Hippocampal/*physiology
Excitatory Postsynaptic Potentials/*drug effects
Lactic Acid/*pharmacology
Synapses/*metabolism
Animals ; CA3 Region, Hippocampal/drug effects ; Calcium/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Cholera Toxin/pharmacology ; Male ; Neuronal Plasticity ; Oxamic Acid/pharmacology ; Protein Kinase C/metabolism ; Rats ; Rats, Sprague-Dawley ; Receptors, N-Methyl-D-Aspartate/metabolism ; Signal Transduction
Czasopismo naukowe
Tytuł :
Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation.
Autorzy :
Gould NL; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
Sharma V; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
Hleihil M; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
Kolatt Chandran S; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
David O; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
Edry E; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.; Center for Gene Manipulation in the Brain, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
Rosenblum K; Sagol Department of Neuroscience, University of Haifa, Mount Carmel, Haifa, 3498838, Israel .; Center for Gene Manipulation in the Brain, University of Haifa, Mount Carmel, Haifa, 3498838, Israel.
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Źródło :
The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Nov 04; Vol. 40 (45), pp. 8698-8714. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal/*physiology
Dopamine/*physiology
Interneurons/*physiology
Memory/*physiology
Quinone Reductases/*physiology
Signal Transduction/*physiology
Aging/physiology ; Aging/psychology ; Animals ; CA1 Region, Hippocampal/growth & development ; Dopamine Antagonists/pharmacology ; Fear/psychology ; Male ; Memory Consolidation/physiology ; Memory, Long-Term ; Mice ; Mice, Inbred C57BL ; MicroRNAs/biosynthesis ; MicroRNAs/genetics ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Recognition, Psychology ; Shab Potassium Channels/metabolism
Czasopismo naukowe
Tytuł :
Hippocampal neurons with stable excitatory connectivity become part of neuronal representations.
Autorzy :
Castello-Waldow TP; Max Planck Institute of Psychiatry, Munich, Germany.
Weston G; Max Planck Institute of Psychiatry, Munich, Germany.; Graduate School of Systemic Neurosciences Ludwig-Maximilians-Universität, Munich, Germany.
Ulivi AF; Max Planck Institute of Psychiatry, Munich, Germany.
Chenani A; Max Planck Institute of Psychiatry, Munich, Germany.
Loewenstein Y; The Hebrew University, Jerusalem, Israel.
Chen A; Max Planck Institute of Psychiatry, Munich, Germany.; Graduate School of Systemic Neurosciences Ludwig-Maximilians-Universität, Munich, Germany.; Weizmann Institute of Science, Rehovot, Israel.
Attardo A; Max Planck Institute of Psychiatry, Munich, Germany.; Graduate School of Systemic Neurosciences Ludwig-Maximilians-Universität, Munich, Germany.
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Źródło :
PLoS biology [PLoS Biol] 2020 Nov 03; Vol. 18 (11), pp. e3000928. Date of Electronic Publication: 2020 Nov 03 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
CA1 Region, Hippocampal/*physiology
Memory/*physiology
Pyramidal Cells/*physiology
Animals ; CA1 Region, Hippocampal/cytology ; Conditioning, Psychological ; Cytoskeletal Proteins/genetics ; Cytoskeletal Proteins/physiology ; Dendritic Spines/physiology ; Fear/physiology ; Female ; Genes, Immediate-Early ; Green Fluorescent Proteins/genetics ; Male ; Mental Recall/physiology ; Mice ; Mice, Transgenic ; Models, Neurological ; Models, Psychological ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/physiology ; Neuronal Plasticity/physiology ; Promoter Regions, Genetic
Czasopismo naukowe

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