Autor: "Regmi SC" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Proteoglycan-4 and hyaluronan composition in synovial fluid and serum from clinical equine subjects: relationship to cartilage boundary lubrication and viscosity of synovial fluid.
Autorzy:: Matheson A; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.
Regmi SC; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.
Martin-Alarcon L; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.
Jay GD; Department of Emergency Medicine - Warren Alpert Medical School & School of Engineering, Brown University, Providence, RI, USA.
Scott WM; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.; Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.
Schmidt TA; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.; Biomedical Engineering Department, University of Connecticut Health Center, Farmington, CT, USA.; Pokaż więcej
Źródło:: Connective tissue research [Connect Tissue Res] 2021 Jul; Vol. 62 (4), pp. 369-380. Date of Electronic Publication: 2020 Apr 20.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cartilage, Articular*
Osteoarthritis*/veterinary
Osteochondrosis*
Animals ; Horses ; Hyaluronic Acid ; Immunosorbents ; Lubrication ; Proteoglycans ; Synovial Fluid ; Viscosity

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Skocz do pozycji: 2.

Tytuł:: Recombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway.
Autorzy:: Sarkar A; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Chanda A; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Regmi SC; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Karve K; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Deng L; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jay GD; Department of Emergency Medicine-Alpert Medical School & School of Engineering, Brown University, Providence, Rhode Island, United States of America.
Jirik FR; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Schmidt TA; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.; Biomedical Engineering Department, University of Connecticut Health Center, Farmington, Connecticut, United States of America.
Bonni S; The Arnie Charbonneau Cancer Institute and Department of Biochemistry & Molecular Biology, The Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2019 Jul 30; Vol. 14 (7), pp. e0219697. Date of Electronic Publication: 2019 Jul 30 (Print Publication: 2019).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Signal Transduction*
Breast Neoplasms/*drug therapy
Breast Neoplasms/*metabolism
Hyaluronan Receptors/*metabolism
Hyaluronic Acid/*metabolism
Proteoglycans/*metabolism
Recombinant Proteins/*therapeutic use
Transforming Growth Factor beta/*metabolism
Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Female ; Humans ; Molecular Weight ; Neoplasm Invasiveness ; Organoids/drug effects ; Organoids/pathology ; Recombinant Proteins/pharmacology ; Smad Proteins/metabolism

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Skocz do pozycji: 3.

Tytuł:: Prevalence and correlates of postabortion long-acting reversible contraceptive (LARC) use among young women (24 and below) in Nepal: Strategy in the search for improvements.
Autorzy:: Mehata S; Ipas Nepal, Baluwatar, Do Cha Marg, Ward No.: 04, Kathmandu, 44600, Nepal.; Ministry of Health, Ram Shah Path, Kathmandu, 44600, Nepal.
Bhattarai N; Ipas Nepal, Baluwatar, Do Cha Marg, Ward No.: 04, Kathmandu, 44600, Nepal.
Menzel J; Ipas, P.O. Box 9990, Chapel Hill, NC, 27515, USA.
Shah M; Ipas Nepal, Baluwatar, Do Cha Marg, Ward No.: 04, Kathmandu, 44600, Nepal.
Khanal P; Institute of Medicine, Kathmandu, Nepal.
Tofigh S; Ipas, P.O. Box 9990, Chapel Hill, NC, 27515, USA.
Khanal MN; Ministry of Health, Ram Shah Path, Kathmandu, 44600, Nepal.
Regmi SC; Ipas Nepal, Baluwatar, Do Cha Marg, Ward No.: 04, Kathmandu, 44600, Nepal.
Andersen K; Ipas, P.O. Box 9990, Chapel Hill, NC, 27515, USA. .; Pokaż więcej
Źródło:: Reproductive health [Reprod Health] 2019 May 14; Vol. 16 (1), pp. 55. Date of Electronic Publication: 2019 May 14.
Typ publikacji:: Journal Article
MeSH Terms:: Long-Acting Reversible Contraception*
Contraception Behavior/*trends
Abortion, Induced/statistics & numerical data ; Aftercare ; Cohort Studies ; Contraception Behavior/statistics & numerical data ; Female ; Humans ; Nepal ; Pregnancy ; Pregnancy, Unplanned ; Young Adult

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Skocz do pozycji: 4.

Tytuł:: Investigating the effect of proteoglycan 4 on hyaluronan solution properties using confocal fluorescence recovery after photobleaching.
Autorzy:: Bloom AK; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.
Samsom ML; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada.
Regmi SC; Faculty of Kinesiology, KNB 426, 2500 University Dr. NW, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Steele BL; Faculty of Kinesiology, KNB 426, 2500 University Dr. NW, University of Calgary, Calgary, AB, T2N 1N4, Canada.
Schmidt TA; Biomedical Engineering Graduate Program, University of Calgary, Calgary, AB, Canada. .; Faculty of Kinesiology, KNB 426, 2500 University Dr. NW, University of Calgary, Calgary, AB, T2N 1N4, Canada. .; Biomedical Engineering Department, University of Connecticut Health Center, Farmington, CT, USA. .; Pokaż więcej
Źródło:: BMC musculoskeletal disorders [BMC Musculoskelet Disord] 2019 Feb 26; Vol. 20 (1), pp. 93. Date of Electronic Publication: 2019 Feb 26.
Typ publikacji:: Journal Article
MeSH Terms:: Fluorescence Recovery After Photobleaching/*methods
Hyaluronic Acid/*metabolism
Hyaluronic Acid/*pharmacology
Proteoglycans/*metabolism
Proteoglycans/*pharmacology
Animals ; Cattle ; Dose-Response Relationship, Drug ; Microscopy, Confocal/methods ; Pharmaceutical Solutions/metabolism ; Pharmaceutical Solutions/pharmacology

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Skocz do pozycji: 5.

Tytuł:: Tryptophan hydroxylase 1 and 5-HT 7 receptor preferentially expressed in triple-negative breast cancer promote cancer progression through autocrine serotonin signaling.
Autorzy:: Gautam J; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea.
Banskota S; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea.
Regmi SC; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea.
Ahn S; Department of Nuclear Medicine, Kyungpook National University, Daegu, 41944, Republic of Korea.
Jeon YH; Department of Nuclear Medicine, Kyungpook National University, Daegu, 41944, Republic of Korea.
Jeong H; Departments of Pharmacy Practice and Biopharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Kim SJ; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea.
Nam TG; Department of Pharmacy, Hanyang University, Ansan, 15588, Republic of Korea.
Jeong BS; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea. .
Kim JA; College of Pharmacy, Yeungnam University, 280 Daehak-Ro, Gyeongsan, 38541, Republic of Korea. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2016 Nov 21; Vol. 15 (1), pp. 75. Date of Electronic Publication: 2016 Nov 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Autocrine Communication*
Receptors, Serotonin/*genetics
Serotonin/*metabolism
Triple Negative Breast Neoplasms/*genetics
Triple Negative Breast Neoplasms/*metabolism
Tryptophan Hydroxylase/*genetics
Animals ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cyclic AMP/metabolism ; Disease Models, Animal ; Disease Progression ; Female ; Humans ; Mice ; Models, Biological ; Receptors, Serotonin/metabolism ; Serotonin/pharmacology ; Serotonin Antagonists/pharmacology ; Signal Transduction/drug effects ; Triple Negative Breast Neoplasms/pathology ; Tryptophan Hydroxylase/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 6.

Tytuł:: BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway.
Autorzy:: Banskota S; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Gautam J; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Regmi SC; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Gurung P; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Park MH; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Kim SJ; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Nam TG; Department of Pharmacy, Hanyang University, Ansan, 15588, Republic of Korea.
Jeong BS; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.
Kim JA; College of Pharmacy, Yeungnam University, Gyeongsan, 38541, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2016 Jan 29; Vol. 11 (1), pp. e0148133. Date of Electronic Publication: 2016 Jan 29 (Print Publication: 2016).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Aminopyridines/*pharmacology
Angiogenesis Inhibitors/*pharmacology
Aniline Compounds/*pharmacology
Chorioallantoic Membrane/*drug effects
NADPH Oxidases/*genetics
Neovascularization, Pathologic/*prevention & control
Phosphatidylinositol 3-Kinases/*genetics
Aminopyridines/chemical synthesis ; Angiogenesis Inducing Agents/pharmacology ; Angiogenesis Inhibitors/chemical synthesis ; Aniline Compounds/chemical synthesis ; Animals ; Cell Line, Tumor ; Cell Movement/drug effects ; Chick Embryo ; Chorioallantoic Membrane/blood supply ; Chorioallantoic Membrane/pathology ; GTP-Binding Protein beta Subunits/genetics ; GTP-Binding Protein beta Subunits/metabolism ; Human Umbilical Vein Endothelial Cells/cytology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; MCF-7 Cells ; NADPH Oxidases/antagonists & inhibitors ; NADPH Oxidases/metabolism ; Neovascularization, Pathologic/chemically induced ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Oxidation-Reduction ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphoinositide-3 Kinase Inhibitors ; Phosphorylation ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Receptors, Serotonin, 5-HT1/genetics ; Receptors, Serotonin, 5-HT1/metabolism ; Serotonin/pharmacology ; Signal Transduction ; p38 Mitogen-Activated Protein Kinases/genetics ; p38 Mitogen-Activated Protein Kinases/metabolism ; src-Family Kinases/genetics ; src-Family Kinases/metabolism

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Skocz do pozycji: 7.

Tytuł:: Lubricin/Proteoglycan 4 binds to and regulates the activity of Toll-Like Receptors In Vitro.
Autorzy:: Iqbal SM; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Leonard C; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Regmi SC; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
De Rantere D; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Tailor P; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Ren G; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Ishida H; Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Hsu C; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Abubacker S; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Pang DS; Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.
Salo PT; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Vogel HJ; Faculty of Science, University of Calgary, Calgary, Alberta, Canada.
Hart DA; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Waterhouse CC; Snyder Institute, Cummings School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Jay GD; Faculty of Medicine, Brown University, Providence, Rhode Island, United States.
Schmidt TA; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.; Schulich School of Engineering, University of Calgary, Calgary, Alberta, Canada.
Krawetz RJ; McCaig Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jan 11; Vol. 6, pp. 18910. Date of Electronic Publication: 2016 Jan 11.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Glycoproteins/*metabolism
Toll-Like Receptors/*metabolism
Adult ; Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Cytokines/metabolism ; Disease Models, Animal ; Fibroblasts/drug effects ; Fibroblasts/metabolism ; Fibroblasts/pathology ; Humans ; Hyaluronic Acid/metabolism ; Inflammation/pathology ; Lipopolysaccharides/pharmacology ; NF-kappa B/metabolism ; Osteoarthritis/pathology ; Protein Binding/drug effects ; Protein Transport/drug effects ; Rats

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Skocz do pozycji: 8.

Tytuł:: The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the β-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
Autorzy:: Regmi SC; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Park SY; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Kim SJ; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Banskota S; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Shah S; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Kim DH; Research and Development Center, Daewoo Pharm. Co. Ltd, Busan, Republic of Korea.
Kim JA; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Nov 06; Vol. 10 (11), pp. e0141753. Date of Electronic Publication: 2015 Nov 06 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Phosphoinositide-3 Kinase Inhibitors*
Antineoplastic Agents/*pharmacology
Enzyme Inhibitors/*pharmacology
Macrolides/*pharmacology
Proto-Oncogene Proteins c-akt/*antagonists & inhibitors
Tankyrases/*antagonists & inhibitors
beta Catenin/*metabolism
Active Transport, Cell Nucleus/drug effects ; Animals ; Antineoplastic Combined Chemotherapy Protocols ; Axin Protein/metabolism ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Cell Proliferation/drug effects ; HCT116 Cells ; HT29 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; TCF Transcription Factors/metabolism ; Transcription, Genetic/drug effects ; Wnt Signaling Pathway/drug effects ; Xenograft Model Antitumor Assays

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Skocz do pozycji: 9.

Tytuł:: NOX1 to NOX2 switch deactivates AMPK and induces invasive phenotype in colon cancer cells through overexpression of MMP-7.
Autorzy:: Banskota S; College of Pharmacy, Yeungnam University, Gyeongsan, 712-749, South Korea. .
Regmi SC; College of Pharmacy, Yeungnam University, Gyeongsan, 712-749, South Korea. .
Kim JA; College of Pharmacy, Yeungnam University, Gyeongsan, 712-749, South Korea. .; Pokaż więcej
Źródło:: Molecular cancer [Mol Cancer] 2015 Jun 27; Vol. 14, pp. 123. Date of Electronic Publication: 2015 Jun 27.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Gene Expression*
AMP-Activated Protein Kinases/*metabolism
Colonic Neoplasms/*genetics
Colonic Neoplasms/*metabolism
Matrix Metalloproteinase 7/*genetics
Membrane Glycoproteins/*metabolism
NADPH Oxidases/*metabolism
Cell Line, Tumor ; Cell Movement/genetics ; Colonic Neoplasms/pathology ; HT29 Cells ; Humans ; Membrane Glycoproteins/genetics ; NADPH Oxidase 1 ; NADPH Oxidase 2 ; NADPH Oxidases/genetics ; Phenotype ; Phosphorylation ; Reactive Oxygen Species/metabolism ; Signal Transduction

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