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Tytuł :
Evidence-based regulations for bioinformatic prediction of allergen cross-reactivity are needed.
Autorzy :
Herman RA; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 47968, USA. Electronic address: .
Song P; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 47968, USA.
Mirsky HP; Corteva Agriscience, 8325 NW 62nd Avenue, Johnston, IA, 50131, USA.
Roper JM; Corteva Agriscience, P.O. Box 30 Newark DE, 19714, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104841. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples.
Autorzy :
Holland EB; Department of Biological Sciences, California State University of Long Beach, Long Beach, CA, USA. Electronic address: .
Pessah IN; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104842. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humans.
Autorzy :
Dekant W; Department of Pharmacology and Toxicology, Universität Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany.
Jean P; Olin Corporation, 2205 Ridgewood Dr., Midland, MI, 48642 USA.
Arts J; Nouryon Industrial Chemicals, PO Box 60192, 6800 JD Arnhem, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104858. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Skin immune cell characterization in juvenile and adult Göttingen Minipigs.
Autorzy :
Allais L; Charles River, Saint-Germain-Nuelles, France. Electronic address: .
Brisebard E; Charles River, Saint-Germain-Nuelles, France.
Ravas N; Charles River, Saint-Germain-Nuelles, France.
Briffaux JP; Charles River, Saint-Germain-Nuelles, France.
Pallardy M; Université Paris-Saclay, Inserm, Inflammation, Microbiome and Immunosurveillance, Faculté de Pharmacie, 92290, Châtenay-Malabry, France.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104861. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Autorzy :
Zabka TS; Genentech Inc, 1 DNA Way, South San Francisco, CA, USA. Electronic address: .
Burkhardt J; Pfizer, 1 Eastern Point Road, Groton, CT, USA. Electronic address: .
Reagan WJ; Pfizer, 1 Eastern Point Road, Groton, CT, USA. Electronic address: .
Gautier JC; Sanofi, 13, Quai Jules Guesde, Vitry-sur-Seine, France. Electronic address: .
Glaab WE; Merck & Co, 770 Sumneytown Pike, West Point, PA, USA. Electronic address: .
Guffroy M; AbbVie, 1 North Waukegan Road, North Chicago, IL, USA. Electronic address: .
Harding J; AstraZeneca, Da Vinci Building, Melbourn Science Park, Cambridge Road, Melbourn, Royston, Hertfordshire, UK. Electronic address: .
Brees D; Novartis, 4057 Basel, Basel-stadt, Switzerland. Electronic address: .
McDuffie E; Janssen, 3210 Merryfield Row, San Diego, CA, USA. Electronic address: .
Ramaiah L; Pfizer, 401 North Middletown Road, Pearl River, NY, USA. Electronic address: .
Schultze AE; Lilly Research Laboratories, 893 S Delaware St, Indianapolis, IN, USA. Electronic address: .
Smith JD; Boehringer Ingelheim, 900 Ridgebury Rd, Ridgefield, CT, USA. Electronic address: .
Wolfreys A; UCB Biopharma, Bath Road, Slough, Berkshire, UK. Electronic address: .
Dalmas DA; GlaxoSmithKline, 1250 S. Collegeville Rd, Collegeville, PA, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104857. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling.
Autorzy :
Bercu J; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Masuda-Herrera MJ; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Trejo-Martin A; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Hasselgren C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Lord J; Ultragenyx, 60 Leveroni Court, Novato, CA, 94949, USA.
Graham J; Bristol Myers Squibb, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
Schmitz M; AbbVie Inc., North Chicago, IL, USA.
Milchak L; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
Owens C; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
Lal SH; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Robinson RM; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Whalley S; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Bellion P; DSM Nutritional Products, Kaiseraugst, Switzerland.
Vuorinen A; DSM Nutritional Products, Kaiseraugst, Switzerland.
Gromek K; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
Hawkins WA; GlaxoSmithKline, Park Road, Ware, Hertfordshire, SG12 0DP, United Kingdom.
van de Gevel I; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
Vriens K; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
Kemper R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
Naven R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
Ferrer P; Department of Veterinary Physiology and Pharmacology, Interdisciplinary Faculty of Toxicology Program, Texas A&M University, 4466 TAMU, College Station, TX, 77843-4466, USA.
Myatt GJ; Leadscope (an Instem company), 1393 Dublin Rd, Columbus, OH, 43215, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104843. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Risk assessment of predicted serum concentrations of bisphenol A in children and adults following treatment with dental composite restoratives, dental sealants, or orthodontic adhesives using physiologically based pharmacokinetic modeling.
Autorzy :
Bagley BD; 3M Corporate Toxicology and Environmental Science, 3M Center, St. Paul, MN, 55144-1000, USA. Electronic address: .
Smith JN; Exposure Science, Pacific Northwest National Laboratory, Richland, WA, 99352, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 93771, USA.
Teeguarden JG; Exposure Science, Pacific Northwest National Laboratory, Richland, WA, 99352, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 93771, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104839. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Estimation of toluene exposure in air from BMA (S-benzylmercapturic acid) urinary measures using a reverse dosimetry approach based on physiologically pharmacokinetic modeling.
Autorzy :
Tohon H; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada.
Valcke M; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada; Direction de la santé environnementale et de la toxicologie, Institut national de santé publique du Québec, Montréal, Quebec, Canada.
Aranda-Rodriguez R; Exposure and Biomonitoring Division, Environmental Health Sciences and Research Bureau, Health Canada, Ottawa, ON, Canada.
Nong A; Exposure and Biomonitoring Division, Environmental Health Sciences and Research Bureau, Health Canada, Ottawa, ON, Canada.
Haddad S; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104860. Date of Electronic Publication: 2021 Jan 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A 13-week subchronic toxicity study of a Dioscorea Rhizome water extract in rats.
Autorzy :
Cha SB; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim HS; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Bae JS; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Song SW; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Lim JO; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim JC; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104844. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyrene.
Autorzy :
Magee BH; Arcadis U.S., Inc., One Executive Drive, Suite 303, Chelmsford, MA, 01824, United States. Electronic address: .
Forsberg ND; Arcadis U.S., Inc, 855 Route 146, Suite 210, Clifton Park, NY, 12065, United States.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104852. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Comparative In vitro metabolism of purified mogrosides derived from monk fruit extracts.
Autorzy :
Bhusari S; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA. Electronic address: .
Rodriguez C; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA.
Tarka SM Jr; The Tarka Group Inc., 210 N. Old Stonehouse Road, Carlisle, PA, 17015, USA.
Kwok D; BRI Biopharmaceutical Research Inc., 101-8898 Heather St, Vancouver, BC, V6P 3S8, Canada.
Pugh G; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA.
Gujral J; Tate & Lyle, 5450 Prairie Stone Parkway, Hoffman Estates, IL, 60192, USA.
Tonucci D; Tate & Lyle, 5450 Prairie Stone Parkway, Hoffman Estates, IL, 60192, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104856. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Quantifying bias in epidemiologic studies evaluating the association between acetaminophen use and cancer.
Autorzy :
Schuemie MJ; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA. Electronic address: .
Weinstein R; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA.
Ryan PB; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA.
Berlin JA; Department of Epidemiology, Johnson & Johnson, Titusville, NJ, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104866. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Incorporating lines of evidence from New Approach Methodologies (NAMs) to reduce uncertainties in a category based read-across: A case study for repeated dose toxicity.
Autorzy :
Pestana CB; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.
Firman JW; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.
Cronin MTD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104855. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reproductive and developmental toxicity screening study of an acetone extract of rosemary.
Autorzy :
Phipps KR; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK. Electronic address: .
Danielewska-Nikiel B; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Mushonganono J; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Baldwin N; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104840. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential.
Autorzy :
Jaeschke H; University of Kansas Medical Center, Department of Pharmacology, Toxicology & Therapeutics, Kansas City, KS, USA.
Murray FJ; Murray & Associates, San Jose, CA, USA.
Monnot AD; Cardno ChemRisk, San Fransisco, CA, USA.
Jacobson-Kram D; ToxRox Consulting, McLean, VA, USA.
Cohen SM; University of Nebraska Medical Center, Havlik-Wall Professor of Oncology, Department of Pathology and Microbiology, Omaha, NE, USA.
Hardisty JF; Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, USA.
Atillasoy E; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Hermanowski-Vosatka A; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Kuffner E; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Wikoff D; ToxStrategies, Asheville, NC, USA.
Chappell GA; ToxStrategies, Asheville, NC, USA.
Bandara SB; Cardno ChemRisk, San Fransisco, CA, USA.
Deore M; Johnson & Johnson Consumer Products, India.
Pitchaiyan SK; Johnson & Johnson Consumer Products, India.
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104859. Date of Electronic Publication: 2021 Jan 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
How Sensitive does Chemical Characterization of Medical Devices Need To Be? Calibration of Analytical Evaluation Thresholds with the Carcinogenic Potency Database.
Autorzy :
Kennedy TA; W.L. Gore & Associates, Inc. P. O. Box 2400, Flagstaff, AZ, 86003-2400, USA. Electronic address: .
Spinti MJ; W.L. Gore & Associates, Inc. P. O. Box 2400, Flagstaff, AZ, 86003-2400, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 20, pp. 104899. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Purification of Bhallathaka (Semecarpus anacardium L.f.) enhanced anti-cancer activity.
Autorzy :
T SC; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India. Electronic address: .
M D; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
K PT; Department of Pharmacology, JSS College of Pharmacy, Ooty, 643001, Tamil Nadu, India.
R LK; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
M AE; Product Development Department, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
M S; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
Balachandran I; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 20, pp. 104898. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Regulatory landscape of nanotechnology and nanoplastics from a global perspective.
Autorzy :
Allan J; Joint Institute for Innovation Policy, Belgium.
Belz S; European Commission, Joint Research Centre (JRC), Italy.
Hoeveler A; European Commission, Joint Research Centre (JRC), Italy.
Hugas M; European Food Safety Authority (EFSA), Italy.
Okuda H; National Institute of Health Sciences (NIHS), Japan.
Patri A; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Rauscher H; European Commission, Joint Research Centre (JRC), Italy.
Silva P; Canadian Food Inspection Agency, Canada.
Slikker W; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Sokull-Kluettgen B; European Commission, Joint Research Centre (JRC), Italy.
Tong W; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Anklam E; European Commission, Joint Research Centre (JRC), Belgium. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 19, pp. 104885. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Epidemiology of Lung Cancer Among Acrylonitrile-Exposed Study Populations: A Meta-Analysis.
Autorzy :
Alexander DD; MetaMethod, South Lyon, MI. Electronic address: .
Pastula ST; Ann Arbor, MI.
Riordan AS; Chicago, IL.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 19, pp. 104896. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via Uridine 5'-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation.
Autorzy :
Bomann W; Toxconsult, 9393 W 110(th) Street, 51 Corporate Woods, Suite 500, Overland Park, KS, 66210, USA.
Tinwell H; Bayer.SAS, 16 rue Jean-Marie Leclair, 69009, Lyon, France.
Jenkinson P; CEHTRA Ltd, Nottingham, UK.
Kluxen F; ADAMA Deutschland GmbH, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 14, pp. 104884. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Comprehensive Weight of Evidence Assessment of Published Acetaminophen Genotoxicity Data: Implications for its Carcinogenic Hazard Potential.
Autorzy :
Kirkland D; Kirkland Consulting, Tadcaster LS24 0AS, UK.
Kovochich M; Cardno ChemRisk, Chicago, IL, USA.
More S; Cardno ChemRisk, Portland, OR, USA.
Murray FJ; Murray & Associates, San Jose, CA, USA.
Monnot AD; Cardno ChemRisk, San Francisco, CA, USA.
Miller J; Cardno ChemRisk, Pittsburgh, PA, USA.
Jaeschke H; University of Kansas Medical Center, Kansas City, KS, USA.
Jacobson-Kram D; ToxRox Consulting, McLean, VA, USA.
Deore M; Johnson & Johnson Consumer, India.
Pitchaiyan SK; Johnson & Johnson Consumer, India.
Unice K; Cardno ChemRisk, Pittsburgh, PA, USA.
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 13, pp. 104892. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Disease area and mode of action as criteria to asssign a default occupational exposure limit.
Autorzy :
Glogovac M; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland. Electronic address: .
Paulson C; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland. Electronic address: .
Lambert A; Novartis Institutes for BioMedical Research, Cambridge, USA; Roche Innovation Center Zurich, Wagistrasse 10, CH-8952, Schlieren, Switzerland. Electronic address: .
Winkler GC; Novartis Pharma AG NIBR, Postfach, CH-4002, Basel, Switzerland; Preclinical Safety Consultant, In den Reben 229, CH-5063, Oberhof, Switzerland. Electronic address: .
Lovsin Barle E; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland; Takeda Pharmaceutical Company Limited, Thurgauerstrasse 130, CH-8152, Glattpark (Opfikon), Switzerland. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104891. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Probabilistic pharmacokinetic modeling of airborne lead corresponding to toxicologically relevant blood lead levels in workers.
Autorzy :
Sweeney LM; UES, Inc., assigned to Air Force Research Laboratory, 711th Human Performance Wing, 4401 Dayton-Xenia Road, Dayton, OH, 45432, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104894. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vivo safety testing of Antibody Drug Conjugates.
Autorzy :
Pretto F; University of Geneva, Faculty of Medicine, Rue Michel-Servet 1, 1206 Genève, Switzerland. Electronic address: .
FitzGerald R; University of Basel, Department of Pharmaceutical Sciences, Swiss Centre for Applied Human Toxicology, SCAHT, Missionsstrasse 64, 4055 Basel, Switzerland.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12, pp. 104890. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog.
Autorzy :
Nandanwar M; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India. Electronic address: .
Chavan R; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Kansagara A; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel MA; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel A; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Yeole R; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel M; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104889. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow.
Autorzy :
Mombelli E; Institut National de l'Environnement Industriel et des Risques (INERIS), 60550, Verneuil en Halatte, France. Electronic address: .
Pandard P; Institut National de l'Environnement Industriel et des Risques (INERIS), 60550, Verneuil en Halatte, France.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104893. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmetics.
Autorzy :
López-Sánchez L; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain.
Miralles P; Departament of Analytical Chemistry, Faculty of Chemistry. University of Valencia, Valencia, Spain.
Salvador A; Departament of Analytical Chemistry, Faculty of Chemistry. University of Valencia, Valencia, Spain.
Merino-Sanjuán M; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain. Electronic address: .
Merino V; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain.
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Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 09; Vol. 122, pp. 104888. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Assessment of the toxicity and toxicokinetics of the novel potent tropomyosin receptor kinase (Trk) inhibitor LPM4870108 in rhesus monkeys.
Autorzy :
Duan S; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Dong L; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Wang B; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Wei S; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Gong X; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Yu P; School of Public Health and Management, Binzhou Medical University, Yantai, 264003, PR China.
Li C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Gao Y; School of Life Science, Yantai University, Yantai, 264005, PR China.
Ye L; School of Public Health and Management, Binzhou Medical University, Yantai, 264003, PR China.
Wang H; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
Tian J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 06; Vol. 122, pp. 104886. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Butylated hydroxyanisole: Carcinogenic food additive to be avoided or harmless antioxidant important to protect food supply?
Autorzy :
Felter SP; Procter & Gamble, Central Product Safety, Mason, OH, USA. Electronic address: .
Zhang X; Procter & Gamble, Central Product Safety, Mason, OH, USA.
Thompson C; ToxStrategies, Katy, TX, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 06; Vol. 121, pp. 104887. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Utilisation of parametric methods to improve percentile-based estimates for the carcinogenic potency of nitrosamines.
Autorzy :
Thomas R; Lhasa Limited, Granary Wharf House, Leeds, UK. Electronic address: .
Thresher A; Lhasa Limited, Granary Wharf House, Leeds, UK.
Ponting DJ; Lhasa Limited, Granary Wharf House, Leeds, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 05; Vol. 121, pp. 104875. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The performance, reliability and potential application of in silico models for predicting the acute oral toxicity of pharmaceutical compounds.
Autorzy :
Graham JC; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA. Electronic address: .
Rodas M; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
Hillegass J; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
Schulze G; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104816. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of dietary dose administration as an alternative to oral gavage in the rodent uterotrophic and Hershberger assays.
Autorzy :
Markell LK; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA. Electronic address: .
O'Connor JC; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
Luo R; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA.
Klems JP; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA.
Sayers BC; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
Mingoia RT; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104820. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Simple methodology for ensuring the precision of measuring radioactivity at low concentrations in very small tissues using quantitative whole-body autoradiography.
Autorzy :
Hironaka T; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan; Development of Drug Safety & DMPK, Research Area for Candidate Selection, Shionogi TechnoAdvance Research Co., Ltd., Toyonaka, Osaka, Japan. Electronic address: .
Inazawa K; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan; Development of Drug Safety & DMPK, Research Area for Candidate Selection, Shionogi TechnoAdvance Research Co., Ltd., Toyonaka, Osaka, Japan.
Tanaka Y; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan.
Hasegawa H; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104835. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Subchronic toxicity study in rats evaluating herbicide-tolerant soybean DAS-68416-4.
Autorzy :
Zhang L; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Li SF; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Zhou QH; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Liu YH; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Zhang J; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Qian ZY; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104833. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Antimony release from polyester textiles by artificial sweat solutions: A call for a standardized procedure.
Autorzy :
Biver M; Bibliothèque Nationale du Luxembourg, 37D, Avenue John F. Kennedy, L-1855, Luxembourg, Luxembourg.
Turner A; School of Geography, Earth and Environmental Sciences, University of Plymouth, Drake Circus, Plymouth, PL4 8AA, UK.
Filella M; Department F.-A. Forel, University of Geneva, Boulevard Carl-Vogt 66, CH-1205, Geneva, Switzerland. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104824. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model.
Autorzy :
Kentrop J; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Savransky V; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Klaassen SD; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
van Groningen T; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Bohnert S; Defense Research and Development Canada - Suffield Research Centre, Casualty Management Section, PO Box 4000 Station Main, Medicine Hat, Alberta, T1A 8K6, Canada.
Cornelissen AS; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Cochrane L; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Barry J; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Joosen MJA; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104823. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Computational identification of preservatives with potential neuronal cytotoxicity.
Autorzy :
Kan HL; Doctoral Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Wang CC; Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, 106, Taiwan.
Lin YC; Doctoral Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. Electronic address: .
Tung CW; Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei, 106, Taiwan; National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli County, 350, Taiwan. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104815. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genotoxicity and subchronic toxicity studies of supercritical carbon dioxide and acetone extracts of rosemary.
Autorzy :
Phipps KR; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK. Electronic address: .
Lozon D; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Baldwin N; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104826. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluating chemical similarity as a measure to identify potential substances of very high concern.
Autorzy :
Wassenaar PNH; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands. Electronic address: .
Rorije E; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands.
Vijver MG; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands.
Peijnenburg WJGM; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104834. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A weight of evidence assessment of the genotoxicity of 2,6-xylidine based on existing and new data, with relevance to safety of lidocaine exposure.
Autorzy :
Kirkland DJ; Kirkland Consulting, P O Box 79, Tadcaster, LS24 0AS, United Kingdom. Electronic address: .
Sheil ML; Animal Ethics Pty Ltd., 363 Steeles Road, Yarra Glen, VIC, 3775, Australia.
Streicker MA; Integrated Laboratory Systems, LLC, 635 Davis Drive, Suite 600, Morrisville, NC, 27560, USA.
Johnson GE; Institute of Life Science, Swansea University Medical School, Singleton Park, Swansea, SA3 5DE, United Kingdom.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104838. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Aloe gel-base food products: Chemical, toxicological, and regulatory aspects.
Autorzy :
Baldi A; Tefarco Innova, National Inter-University Consortium of Innovative Pharmaceutical Technologies, Parco Area delle Scienze 27/A - Campus 43124 Parma, Italy. Electronic address: .
Sommella E; Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy. Electronic address: .
Campiglia P; Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy; European Biomedical Research Institute of Salerno, Via De Renzi 50, I-84125 Salerno, Italy. Electronic address: .
Daglia M; Department of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131, Naples, Italy; International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104818. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
A review to support the derivation of a worst-case dermal penetration value for nanoparticles.
Autorzy :
Gimeno-Benito I; Leitat Technological Center, Innovació 2, 08225, Terrassa, Spain.
Giusti A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max- Dohrn- Strasse 8-10, 10589, Berlin, Germany.
Dekkers S; Rijksinstituut voor Volksgezondheid en Milieu (RIVM), P.O. Box 1, 3720, BA, Bilthoven, the Netherlands.
Haase A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max- Dohrn- Strasse 8-10, 10589, Berlin, Germany.
Janer G; Leitat Technological Center, Innovació 2, 08225, Terrassa, Spain. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104836. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Safety assessment of ethanolic root extract of Zaleya decandra (EEZD) in Wistar rats.
Autorzy :
Deivasigamani M; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India.
Kannan N; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India.
Sekar N; Department of Biotechnology, Sri Ramakrishna College of Arts and Science, Coimbatore, 641 006, Tamil Nadu, India.
Lakshmanan H; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104822. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.
Autorzy :
MacLachlan TK; Department of Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: .
Kronenberg S; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, 4070, Basel, Switzerland.
Marshall N; Non-Clinical Safety, GlaxoSmithKline, 1250 South Collegeville RD, Collegeville, PA, 19426, USA.
Andrews L; Abbvie Preclinical Safety, Worcester, MA, USA, 01605.
Berens SJ; Investigative Toxicology and Pathology, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, 46285, USA.
Brouta F; UCB Biopharma SRL, Non-Clinical Safety Evaluation, 1420, Braine-l'Alleud, Belgium.
Fogal B; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT, 06877, USA.
Freebern W; Bristol Myers Squibb, Drug Safety Evaluation, New Brunswick, NJ, 08903, USA.
Herzyk D; Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA.
Kamperschroer C; Pfizer Worldwide Research & Development, Groton, CT, USA.
Kiessling A; Department of Preclinical Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Schneidkraut M; Astellas Discovery Science and Management, 1 Astellas Way, N2.103, Northbrook, IL, 60062, USA.
Maier C; Non-Clinical Safety, GlaxoSmithKline, 1250 South Collegeville RD, Collegeville, PA, 19426, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104825. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses.
Autorzy :
Kimber I; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104821. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Assessment of the potential allergenicity and toxicity of Pichia proteins in a novel leghemoglobin preparation.
Autorzy :
Reyes TF; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA. Electronic address: .
Chen Y; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Fraser RZ; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Chan T; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Li X; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104817. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A retrospective study on EU harmonised classifications for carcinogenicity to guide future research.
Autorzy :
Terry C; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
Yan Z; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
Corvaro M; Corteva Agriscience, 3B Milton Park Square, OX14 4RN, Abingdon, UK. Electronic address: .
Gehen SC; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104800. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A call for action on the development and implementation of new methodologies for safety assessment of chemical-based products in the EU - A short communication.
Autorzy :
Knight DJ; ECHA, Finland.
Deluyker H; Ex-Scientific Advisor EFSA, Italy.
Chaudhry Q; University of Chester, Parkgate Road, Chester, United Kingdom.
Vidal JM; Consultant toxicologist, London, United Kingdom.
de Boer A; Food Claims Centre Venlo, Campus Venlo, Maastricht University, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104837. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane.
Autorzy :
Lafranconi M; Environmental Resources Management, Cincinnati, OH, USA. Electronic address: .
Budinsky R; Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI, USA.
Corey L; Intertox, Seattle, WA, USA.
Klapacz J; Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI, USA.
Crissman J; StageBio, Mason, OH, USA.
LeBaron M; Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI, USA.
Golden R; Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, MI, USA.
Pleus R; Intertox, Seattle, WA, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104819. Date of Electronic Publication: 2020 Nov 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Grouping of chemicals based on the potential mechanisms of hepatotoxicity of naphthalene and structurally similar chemicals using in vitro testing for read-across and its validation.
Autorzy :
Nakagawa S; Kao Corporation, Safety Science Research, 2606, Akabane, Ichikai-Machi, Haga-Gun, Tochigi, 321-3497, Japan. Electronic address: .
Okamoto M; Kao Corporation, Safety Science Research, 2606, Akabane, Ichikai-Machi, Haga-Gun, Tochigi, 321-3497, Japan.
Yoshihara K; Kao Corporation, Safety Science Research, 2606, Akabane, Ichikai-Machi, Haga-Gun, Tochigi, 321-3497, Japan.
Nukada Y; Kao Corporation, Safety Science Research, 2606, Akabane, Ichikai-Machi, Haga-Gun, Tochigi, 321-3497, Japan.
Morita O; Kao Corporation, Safety Science Research, 2606, Akabane, Ichikai-Machi, Haga-Gun, Tochigi, 321-3497, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 23; Vol. 121, pp. 104874. Date of Electronic Publication: 2021 Jan 23.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Expanding the toxicologist's statistical toolbox: Using effect size estimation and dose-response modelling for holistic assessments instead of generic testing.
Autorzy :
Kluxen FM; ADAMA Deutschland GmbH, Cologne, Germany. Electronic address: .
Jensen SM; Department of Plant and Environmental Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 22; Vol. 121, pp. 104871. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Classic and evolving approaches to evaluating cross reactivity of mAb and mAb-like molecules - A survey of industry 2008-2019.
Autorzy :
MacLachlan TK; Novartis Institutes for Biomedical Research, Cambridge, MA, 01239, USA. Electronic address: .
Price S; Charles River Laboratories, 15 Worman's Mill Court, Suite I, Frederick, MD, 21701, USA.
Cavagnaro J; Access BIO, LC, Boyce, VA, 22620, USA.
Andrews L; AbbVie, 100 Research Dr, Worcester, MA, 01520, USA.
Blanset D; Boehringer Ingelheim, 900 Ridgebury Road, Ridgefield, CT, 06877, USA.
Cosenza ME; MEC Regulatory & Toxicology Consulting, LLC, Moorpark, CA, 93021, USA.
Dempster M; GlaxoSmithKline, 1250 South Collegeville Rd, Collegeville, PA, 19426, USA.
Galbreath E; Drug Safety Research and Evaluation, Takeda US, Inc., Cambridge, MA, USA.
Giusti AM; Roche Pharma Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Zurich, Switzerland.
Heinz-Taheny KM; Toxicology and Pathology, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN, 46285, USA.
Fleurance R; UCB BioPharma SRL, B-1420, Braine L'Alleud, Belgium.
Sutter E; Novartis Institutes for Biomedical Research, Basel, Switzerland.
Leach MW; Drug Safety Research and Development, Pfizer, Inc, 300 Technology Square, Cambridge, MA, 02139, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 22; Vol. 121, pp. 104872. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Mercury in skin-care products in India and consumer exposure risks.
Autorzy :
Pramanik S; Department of Civil Engineering, Indian Institute of Technology (IIT) Hyderabad, Kandi, TS, 502285, India.
Kumar M; Department of Civil Engineering, Indian Institute of Technology (IIT) Hyderabad, Kandi, TS, 502285, India.
Qureshi A; Department of Civil Engineering, Indian Institute of Technology (IIT) Hyderabad, Kandi, TS, 502285, India. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 22; Vol. 121, pp. 104870. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Toxicity of boric acid, borax and other boron containing compounds: A review.
Autorzy :
Hadrup N; National Research Centre for the Working Environment, Copenhagen, DK, 2100, Denmark. Electronic address: .
Frederiksen M; National Research Centre for the Working Environment, Copenhagen, DK, 2100, Denmark.
Sharma AK; Division for Risk Assessment and Nutrition, Group for Chemical Risk Assessment and GMO, National Food Institute, Technical University of Denmark, Denmark. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 22; Vol. 121, pp. 104873. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Human biomonitoring (HBM)-II values for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) - Description, derivation and discussion.
Autorzy :
Schümann M; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany. Electronic address: .
Lilienthal H; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.
Hölzer J; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 21; Vol. 121, pp. 104868. Date of Electronic Publication: 2021 Jan 21.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Nonclinical & clinical interface - extrapolation of nonclinical data to support Phase I clinical studies.
Autorzy :
Baldrick P; Strategic Product Development Consulting, Clinical Development & Commercialization Services, Covance, Harrogate, North Yorkshire, HG3 1PY, United Kingdom. Electronic address: .
Reichl A; Clinical Pharmacology, Medical & Scientific Affairs, Covance, Madison, WI, 53704, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 20; Vol. 121, pp. 104869. Date of Electronic Publication: 2021 Jan 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Carcinogenicity and chronic toxicity of acrolein in rats and mice by two-year inhalation study.
Autorzy :
Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan. Electronic address: .
Yamano S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Senoh H; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Umeda Y; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Hirai S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Saito A; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Kasai T; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
Aiso S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 17; Vol. 121, pp. 104863. Date of Electronic Publication: 2021 Jan 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Draize human repeat insult patch test (HRIPT): Seven decades of pitfalls and progress.
Autorzy :
Bormann JL; University of South Dakota, Sanford School of Medicine, Sioux Falls, SD, 57105, USA. Electronic address: .
Maibach HI; UCSF, Dermatology Department, San Francisco, CA, 94143-0989, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 16; Vol. 121, pp. 104867. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Increasing confidence in waiving dermal toxicity studies: A comparison of oral and dermal acute data with alternative approaches for agrochemicals and products.
Autorzy :
van der Kamp S; Syngenta Ltd., International Research Centre, Jealott's Hill, Bracknell, Berkshire, RG42 6EY, United Kingdom. Electronic address: .
Elliott C; Syngenta Ltd., International Research Centre, Jealott's Hill, Bracknell, Berkshire, RG42 6EY, United Kingdom.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 13; Vol. 121, pp. 104865. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Human Biomonitoring (HBM)-I values for perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) - Description, derivation and discussion.
Autorzy :
Hölzer J; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany. Electronic address: .
Lilienthal H; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.
Schümann M; Department for Hygiene, Social and Environmental Medicine, MA 1/31, Ruhr-University Bochum, Universitätsstrasse 150, 44801, Bochum, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 12; Vol. 121, pp. 104862. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Compounded conservatism in European re-entry worker risk assessment of pesticides.
Autorzy :
Kluxen FM; ADAMA Deutschland GmbH, Cologne, Germany. Electronic address: .
Felkers E; ADAMA Deutschland GmbH, Cologne, Germany.
Baumann J; Bayer AG, Crop Science Division, Monheim, Germany.
Morgan N; Syngenta, Bracknell, United Kingdom.
Wiemann C; BASF Oesterreich GmbH, Agricultural Solutions, Vienna, Austria.
Stauber F; BASF SE, Agricultural Solutions, Ludwigshafen, Germany.
Strupp C; Gowan Crop Protection, Reading, United Kingdom.
Adham S; Corteva Agriscience, Abingdon, United Kingdom.
Kuster CJ; Bayer AG, Crop Science Division, Monheim, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Jan 12; Vol. 121, pp. 104864. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Assessment of veterinary drug residues in food: Considerations when dealing with sub-optimal data.
Autorzy :
Chicoine A; Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada. Electronic address: .
Erdely H; U.S. Food and Drug Administration, Center for Veterinary Medicine, Rockville, USA.
Fattori V; Food Safety and Quality Unit, Food and Agricultural Organization of the United Nations (FAO), Rome, Italy.
Finnah A; German Federal Office of Consumer Protection and Food Safety (BVL), Berlin, Germany.
Fletcher S; Veterinary Medicines Directorate, United Kingdom.
Lipp M; Food Safety and Quality Unit, Food and Agricultural Organization of the United Nations (FAO), Rome, Italy.
Sanders P; French Agency for Food, Environmental and Occupational Health and Safety, Fougeres, France.
Scheid S; German Federal Office of Consumer Protection and Food Safety (BVL), Berlin, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104806. Date of Electronic Publication: 2020 Oct 12.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Rebuttal to the letters to the editors by Terry et al. and Sewell et al. regarding.
Autorzy :
Heringa MB; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
Cnubben NHP; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
Slob W; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
Pronk MEJ; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
Muller A; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
Woutersen M; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands. Electronic address: .
Hakkert BC; National Institute for Public Health and the Environment (RIVM), Centre for Safety of Substances and Products (VSP), Bilthoven, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104803. Date of Electronic Publication: 2020 Oct 19.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
A critical review of the acetaminophen preclinical carcinogenicity and tumor promotion data and their implications for its carcinogenic hazard potential.
Autorzy :
Murray FJ; Murray & Associates, San Jose, CA, USA.
Monnot AD; Cardno ChemRisk, San Francisco, CA, USA.
Jacobson-Kram D; ToxRox Consulting, McLean, VA, USA.
Cohen SM; Havlik-Wall Professor of Oncology, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Hardisty JF; Experimental Pathology Laboratories, Inc., Durham, NC, USA.
Bandara SB; Cardno ChemRisk, San Francisco, CA, USA.
Kovochich M; Cardno ChemRisk, Chicago, IL, USA.
Deore M; Johnson & Johnson Consumer, India.
Pitchaiyan SK; Johnson & Johnson Consumer, India.
Gelotte CK; Johnson & Johnson Consumer Products, USA.
Lai JCK; Johnson & Johnson Consumer Products, USA.
Atillasoy E; Johnson & Johnson Consumer Products, USA.
Hermanowski-Vosatka A; Johnson & Johnson Consumer Products, USA.
Kuffner E; Johnson & Johnson Consumer Products, USA.
Unice KM; Cardno ChemRisk, Pittsburgh, PA, USA.
Yang K; DILIsym Services Inc., Research Triangle Park, NC, USA.
Gebremichael Y; DILIsym Services Inc., Research Triangle Park, NC, USA.
Howell BA; DILIsym Services Inc., Research Triangle Park, NC, USA.
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104801. Date of Electronic Publication: 2020 Oct 09.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Choosing the best for preventing the worst: A structured analysis of the selection of risk management options in REACH restriction dossiers.
Autorzy :
Hilber I; Agroscope, Methods Development and Analytics, Environmental Analytics, Reckenholzstrasse 191, 8046, Zurich, Switzerland. Electronic address: .
Gabbert S; Wageningen University, Department of Social Sciences, Environmental Economics and Natural Resources Group, Hollandseweg 1, 6700, EW Wageningen, the Netherlands; National Institute for Public Health and the Environment (RIVM), Antonie van Leeuwenhoeklaan 9, 3721, MA Bilthoven, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104809. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Statistical analysis of in vivo alkaline comet assay data - Comparison of median and geometric mean as centrality measures.
Autorzy :
Tug T; Faculty of Statistics, TU Dortmund University, 44221, Dortmund, Germany. Electronic address: .
Ickstadt K; Faculty of Statistics, TU Dortmund University, 44221, Dortmund, Germany.
Kunz M; Bayer AG, Research & Early Development Statistics, 13342, Berlin, Germany.
Sutter A; Bayer AG, Pharmaceuticals, Investigational Toxicology, Müllerstr. 178, 13353 Berlin / Bayer AG, Oncology Development - Program Management, 13342, Berlin, Germany.
Igl BW; Bayer AG, Research and Clinical Sciences Statistics, 13342 Berlin, Germany / Boehringer Ingelheim Pharma GmbH & Co. KG, Biostatistics + Data Sciences Corp., 88397, Biberach an der Riss, Germany.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104808. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Acute and sub-chronic toxicity studies of Benincasa hispida (Thunb.) cogniaux fruit extract in rodents.
Autorzy :
Shakya A; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786 004, Assam, India. Electronic address: .
Chaudhary SK; Faculty of Pharmacy, DIT University, Mussoorie-Diversion Road, Makkawala, Dehradun, 248 009, Uttarakhand, India.
Bhat HR; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786 004, Assam, India.
Ghosh SK; Department of Pharmaceutical Sciences, Faculty of Science and Engineering, Dibrugarh University, Dibrugarh, 786 004, Assam, India.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104785. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Considerations when deriving compound-specific limits for extractables and leachables from pharmaceutical products: Four case studies.
Autorzy :
Parris P; Pfizer Worldwide Research and Development, Sandwich, UK. Electronic address: .
Martin EA; AstraZeneca, Cambridge, UK.
Stanard B; Ultragenyx Pharmaceutical Inc., Novato, CA, USA.
Glowienke S; Novartis, Basel, Switzerland.
Dolan DG; Amgen Inc., Thousand Oaks, CA, USA.
Li K; Amgen Inc., Thousand Oaks, CA, USA.
Binazon O; GlaxoSmithKline, Wavre, Belgium.
Giddings A; GlaxoSmithKline, Hertfordshire, UK.
Whelan G; GlaxoSmithKline, Hertfordshire, UK.
Masuda-Herrera M; Gilead Sciences Inc., Foster City, CA, USA.
Bercu J; Gilead Sciences Inc., Foster City, CA, USA.
Broschard T; Merck Healthcare KGaA, Darmstadt, Germany.
Bruen U; Merck & Co., Inc., Kenilworth, NJ, USA.
Callis CM; Lilly Research Laboratories, Eli Lilly & Company, Indianapolis, IN, USA.
Stults CLM; C & M Technical Consulting, LLC, USA.
Erexson GL; AbbVie, Inc., North Chicago, IL, USA.
Cruz MT; Faegre Drinker Biddle & Reath LLP, Washington, DC, USA.
Nagao LM; Faegre Drinker Biddle & Reath LLP, Washington, DC, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104802. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Toxicological risk assessment of bisphenol a released from dialyzers under simulated-use and exaggerated extraction conditions.
Autorzy :
Badding MA; Exponent, Inc, 149 Commonwealth Drive, Menlo Park, CA, 94025, USA. Electronic address: .
Vargas JR; Exponent, Inc, 149 Commonwealth Drive, Menlo Park, CA, 94025, USA.
Fortney J; Exponent, Inc, 149 Commonwealth Drive, Menlo Park, CA, 94025, USA.
Cheng QJ; Fresenius Medical Care, Ltd, 475, West 13th Street, Ogden, UT, 84404, USA.
Ho CH; Fresenius Medical Care, Ltd, 475, West 13th Street, Ogden, UT, 84404, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104787. Date of Electronic Publication: 2020 Oct 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Management of pharmaceutical ICH M7 (Q)SAR predictions - The impact of model updates.
Autorzy :
Hasselgren C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. Electronic address: .
Bercu J; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Cayley A; Lhasa Limited, Granary Wharf House, 2 Canal Wharf, Leeds, UK.
Cross K; Leadscope, Inc. an Instem Company, 1393 Dublin Rd, Columbus, OH, 43215, USA.
Glowienke S; Novartis Pharma AG, Pre-Clinical Safety, Werk Klybeck, CH-4057, Basel, Switzerland.
Kruhlak N; FDA Center for Drug Evaluation and Research, Silver Spring, MD, 20993, USA.
Muster W; Roche Pharmaceutical Research & Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070, Basel, Switzerland.
Nicolette J; AbbVie Inc., Pre-clinical Safety, 1 North Waukegan Road, North Chicago, IL, USA.
Reddy MV; Merck & Co., Inc., West Point, PA, 19486, USA.
Saiakhov R; Multicase Inc., 23811 Chagrin Boulevard, Suite 305, Beachwood, OH, 44122, USA.
Dobo K; Pfizer Worldwide Research & Development, 558 Eastern Point Road, Groton, CT, 06340, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104807. Date of Electronic Publication: 2020 Oct 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Considerations for setting occupational exposure limits for novel pharmaceutical modalities.
Autorzy :
Graham JC; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA. Electronic address: .
Hillegass J; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
Schulze G; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104813. Date of Electronic Publication: 2020 Nov 02.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Facilitation of risk assessment with evidence-based methods - A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty.
Autorzy :
Wikoff D; 31 College Place, Suite B118, Asheville, NC, 28801, USA. Electronic address: .
Lewis RJ; ExxonMobil Biomedical Sciences, Inc., 1545 US Highway 22 East, Room CC291, Annandale, NJ, 08801-3059, USA. Electronic address: .
Erraguntla N; American Chemistry Council, 700 2nd St. NE, Washington, DC, 20002, USA. Electronic address: .
Franzen A; ToxStrategies, Inc, 1800 Forsythe Ave., Suite 2 #148, Monroe, LA, 71201, USA. Electronic address: .
Foreman J; ExxonMobil Chemical Company, Energy 4, E4.3A.478 22777 Springwoods Village Parkway, Spring, TX, 77389, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104790. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applications.
Autorzy :
Hay JL; Medicines & Healthcare Products Regulatory Agency, London, UK; EMA Modelling and Simulation Working Group, UK. Electronic address: .
O'Sullivan J; European Medicines Agency, London, UK.
Kerwash E; Medicines & Healthcare Products Regulatory Agency, London, UK; EMA Modelling and Simulation Working Group, UK.
Ilie AR; University College Cork, Ireland.
Cole SM; Medicines & Healthcare Products Regulatory Agency, London, UK; EMA Modelling and Simulation Working Group, UK; EMA Pharmacokinetics Working Party, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104804. Date of Electronic Publication: 2020 Oct 10.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Thirteen-week oral toxicity study of fermented ginseng, GBCK25, in Sprague-Dawley rats.
Autorzy :
Kim KT; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Cho DW; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Yang MJ; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Kim DH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Shin SH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Hwang JH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea.
Woo DH; Research Center for Convergence Toxicology, Korea Institute of Toxicology, 141 Gajeong-ro, Yuseong-gu, Daejeon, 34114, South Korea.
Shin DG; Research & Development Center of GENERAL BIO Co., Ltd, 254, Yongtusan-ro, Songdong-myeon, Namwon City, Jeollabuk-Do, 55793, Republic of Korea.
Seo JH; Research & Development Center of GENERAL BIO Co., Ltd, 254, Yongtusan-ro, Songdong-myeon, Namwon City, Jeollabuk-Do, 55793, Republic of Korea.
Yang YS; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea. Electronic address: .
Han SC; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeollabuk-Do, 56212, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104812. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The translational value of animal models in orphan medicines designations for rare paediatric neurological diseases.
Autorzy :
Duarte DM; INFARMED, Lisboa, Portugal. Electronic address: .
Beatriz da Silva Lima M; Universidade de Lisboa, Faculdade de Farmácia, Lisbon, Portugal.
Sepodes B; Universidade de Lisboa, Faculdade de Farmácia, Lisbon, Portugal.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104810. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Safety evaluation of Eucommia ulmoides extract.
Autorzy :
Luo X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China.
Wu J; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China.
Li Z; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China.
Jin W; Hebei Medical University, Shijiazhuang, 050017, PR China.
Zhang F; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China.
Sun H; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China.
Shi Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, PR China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104811. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Autorzy :
Luijten M; National Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Bilthoven, the Netherlands. Electronic address: .
Corvi R; European Commission, Joint Research Centre (JRC), Ispra, Italy.
Mehta J; ADAMA Agricultural Solutions Ltd., Reading, UK.
Corvaro M; Corteva Agriscience, Rome, Italy.
Delrue N; Organisation for Economic Cooperation and Development (OECD), Paris, France.
Felter S; Procter & Gamble Company, Mason, OH, USA.
Haas B; Federal Institute for Drugs and Medical Devices, Kurt-Georg-Kiesinger-Allee 3, 53175 Bonn, Germany.
Hewitt NJ; SWS, Wingertstrasse 25, 64390 Erzhausen, Germany.
Hilton G; PETA International Science Consortium Ltd, London, UK.
Holmes T; ADAMA Deutschland GmbH, Cologne, Germany.
Jacobs MN; Centre for Radiation, Chemical and Environmental Hazards (CRCE), Public Health England, UK.
Jacobs A; US Food and Drug Administration (now retired), MD, USA.
Lamplmair F; European Commission, DG Internal Market, Industry, Entrepreneurship and SMEs, Brussels, Belgium.
Lewis D; Syngenta Crop Protection, Bracknell, UK.
Madia F; European Commission, Joint Research Centre (JRC), Ispra, Italy.
Manou I; EPAA Industry Secretariat, Brussels, Belgium.
Melching-Kollmuss S; BASF SE, Limburgerhof, Germany.
Schorsch F; Bayer SAS, Lyon, France.
Schütte K; European Commission, DG Environment, Brussels, Belgium.
Sewell F; National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK.
Strupp C; Gowan Crop Protection, Reading, United Kingdom.
van der Laan JW; Medicines Evaluation Board, Utrecht, the Netherlands.
Wolf DC; Syngenta Crop Protection, LLC, Greensboro, North Carolina, USA.
Wolterink G; National Institute for Public Health and the Environment (RIVM), Centre for Nutrition, Prevention and Health Services, Bilthoven, the Netherlands.
Woutersen R; TNO Innovation for Life, Zeist; Wageningen University and Research, Wageningen, the Netherlands.
Zvonar Z; EPAA Industry Secretariat, Brussels, Belgium.
Heusinkveld H; National Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Bilthoven, the Netherlands.
Braakhuis H; National Institute for Public Health and the Environment (RIVM), Centre for Health Protection, Bilthoven, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104789. Date of Electronic Publication: 2020 Oct 07.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Safety of medicinal comfrey cream preparations (Symphytum officinale s.l.): The pyrrolizidine alkaloid lycopsamine is poorly absorbed through human skin.
Autorzy :
Kuchta K; Forschungsstelle für Fernöstliche Medizin, Department of Vegetation Analysis and Phytodiversity, Albrecht von Haller Institute of Plant Sciences, Georg August University, Untere Karspüle 2, 37073, Göttingen, Germany. Electronic address: .
Schmidt M; Herbresearch Germany, Wartbergweg 15, 86874, Mattsies, Germany. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104784. Date of Electronic Publication: 2020 Sep 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Corrigendum to "28-day somatic gene mutation study of 1-Bromopropane in female big blue® B6C3F1 Mice via whole-Body inhalation: Support for a carcinogenic threshold" [Regul. Toxicol. Pharmacol., 104 (2019) 1-7].
Autorzy :
Stelljes M; SLR International Corporation, Martinez, CA, USA. Electronic address: .
Young R; MilliporeSigma, BioReliance® Testing Services, Rockville, MD, USA.
Weinberg J; Charles River, Ashland, OH, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104814. Date of Electronic Publication: 2020 Nov 03.
Typ publikacji :
Published Erratum
Tytuł :
Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials.
Autorzy :
Api AM; Research Institute for Fragrance Materials, Inc., Woodcliff Lake, NJ, USA. Electronic address: .
Basketter D; Consultant, DABMEB Consultancy Ltd., Sharnbrook, UK.
Bridges J; Member IDEA Supervisory Group, University of Surrey, Guildford, UK.
Cadby P; Consultant, Geneva, Switzerland.
Ellis G; Firmenich SA, 1 Route des Jeunes, Geneva, Switzerland.
Gilmour N; Unilever Safety & Environmental Assurance Centre, Sharnbrook, UK.
Greim H; Member IDEA Supervisory Group, Technical University of Munich, Germany.
Griem P; Symrise AG, Holzminden, Germany.
Kern P; NV Procter & Gamble Services Company SA, Strombeek-Bever, Belgium.
Khaiat A; Member IDEA Supervisory Group, Cosmetics Consultant, Singapore.
O'Brien J; Creme Global, Dublin, Ireland.
Rustemeyer T; Member IDEA Supervisory Group, VU Amsterdam, Netherlands.
Ryan C; The Procter & Gamble Company, Mason, OH, USA.
Safford B; Consultant, B-Safe Toxicology Consulting, Rushden, UK.
Smith B; Innovations in Food and Chemical Safety Programme, Singapore Institute of Food & Biotechnology Innovation, Agency for Science, Technology & Research, Singapore; School of Chemical & Biomedical Engineering, Nanyang Technological University, Singapore.
Vey M; International Fragrance Association, Brussels, Belgium.
White IR; Member IDEA Supervisory Group, St. John's Institute of Dermatology, London, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104805. Date of Electronic Publication: 2020 Oct 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen.
Autorzy :
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, 08901, USA. Electronic address: .
Yang K; DILIsym Services Inc., Research Triangle Park, NC, 27709, USA.
Gebremichael Y; DILIsym Services Inc., Research Triangle Park, NC, 27709, USA.
Howell BA; DILIsym Services Inc., Research Triangle Park, NC, 27709, USA.
Murray FJ; Murray & Associates, San Jose, CA, 95138, USA.
Jacobson-Kram D; ToxRox Consulting LLC, McLean, VA, 22101, USA.
Jaeschke H; University of Kansas Medical Center, Kansas City, KS, 66160, USA.
Kuffner E; Johnson & Johnson, New Brunswick, NJ, 08901, USA.
Gelotte CK; Johnson & Johnson Consumer Products US, Fort Washington, PA, USA.
Lai JCK; Johnson & Johnson Consumer Products US, Fort Washington, PA, USA.
Wikoff D; ToxStrategies, Inc., Asheville, NC, USA.
Atillasoy E; Johnson & Johnson Consumer Products US, Fort Washington, PA, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Dec; Vol. 118, pp. 104788. Date of Electronic Publication: 2020 Oct 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Use of mechanistic information to derive chemical-specific adjustment factors - Refinement of risk assessment.
Autorzy :
Smeraldi C; European Food Safety Authority, FIP Unit, Parma, Italy.
Giarola A; European Food Safety Authority, FIP Unit, Parma, Italy.
Aggett PJ; Emeritus Professor of Child Health and Nutrition, University of Central Lancashire, Preston, UK.
Moldeus P; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Gundert-Remy U; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Clinical Pharmacology and Toxicology, Berlin, Germany. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104776. Date of Electronic Publication: 2020 Aug 29.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Letter to the editor regarding Heringa et al. (2020) paper entitled "Use of the Kinetically-derived Maximum Dose concept in selection of top doses for toxicity studies hampers proper hazard assessment and risk management".
Autorzy :
Terry C; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States. Electronic address: .
Domoradzki JY; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States.
Fleming CR; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States.
Gehen SC; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States.
Mingoia RT; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States.
Murphy LA; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 46268, United States.
Bartels MJ; ToxMetrics.com LLC, Midland, MI, 48642, United States.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104765. Date of Electronic Publication: 2020 Aug 31.
Typ publikacji :
Letter
Opinia redakcyjna
Tytuł :
Analysis and reflection on the role of the 90-day oral toxicity study in European chemical risk assessment.
Autorzy :
Vrolijk M; University College Venlo, Campus Venlo, Maastricht University, the Netherlands.
Deluyker H; Former Scientific Advisor of the European Food Safety Authority (EFSA), the Netherlands.
Bast A; University College Venlo, Campus Venlo, Maastricht University, the Netherlands.
de Boer A; Food Claims Centre Venlo, Campus Venlo, Maastricht University, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104786. Date of Electronic Publication: 2020 Sep 22.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Effects of an ethanolic extract and fractions from Piper glabratum (Piperaceae) leaves on pain and inflammation.
Autorzy :
Leitão MM; Faculty of Health Science, Federal University of Grande Dourados, Highway Dourados/Itahum, Km 12 - Unity II, 79, 804-970, Dourados, MS, Brazil. Electronic address: .
Radai JAS; Faculty of Health Science, Federal University of Grande Dourados, Highway Dourados/Itahum, Km 12 - Unity II, 79, 804-970, Dourados, MS, Brazil. Electronic address: .
Ferrari IC; Faculty of Health Science, Federal University of Grande Dourados, Highway Dourados/Itahum, Km 12 - Unity II, 79, 804-970, Dourados, MS, Brazil. Electronic address: .
Negrão FJ; Faculty of Health Science, Federal University of Grande Dourados, Highway Dourados/Itahum, Km 12 - Unity II, 79, 804-970, Dourados, MS, Brazil. Electronic address: .
Silva-Filho SE; Faculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul, Av. Costa e Silva, University District, 79070-900, Campo Grande, MS, Brazil. Electronic address: .
Oliveira RJ; Faculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul, Av. Costa e Silva, University District, 79070-900, Campo Grande, MS, Brazil. Electronic address: .
Mota JDS; Department of Chemistry, State University of Mato Grosso do Sul, University City of Dourados, 79804-97, Dourados, MS, Brazil. Electronic address: .
Kassuya CAL; Faculty of Health Science, Federal University of Grande Dourados, Highway Dourados/Itahum, Km 12 - Unity II, 79, 804-970, Dourados, MS, Brazil. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104762. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Read-across can increase confidence in the Next Generation Risk Assessment for skin sensitisation: A case study with resorcinol.
Autorzy :
Gautier F; L'Oréal, Research & Innovation, Aulnay-sous-Bois, France; L'Oréal, Research & Innovation, Clichy, France. Electronic address: .
Tourneix F; L'Oréal, Research & Innovation, Aulnay-sous-Bois, France; L'Oréal, Research & Innovation, Clichy, France. Electronic address: .
Assaf Vandecasteele H; L'Oréal, Research & Innovation, Aulnay-sous-Bois, France; L'Oréal, Research & Innovation, Clichy, France. Electronic address: .
van Vliet E; Innovitox Consulting & Services, Regentenland 35, 3994TZ, Houten, the Netherlands. Electronic address: .
Bury D; L'Oréal, Research & Innovation, Aulnay-sous-Bois, France; L'Oréal, Research & Innovation, Clichy, France. Electronic address: .
Alépée N; L'Oréal, Research & Innovation, Aulnay-sous-Bois, France; L'Oréal, Research & Innovation, Clichy, France. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104755. Date of Electronic Publication: 2020 Aug 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Me-too validation study for in vitro skin irritation test with a reconstructed human epidermis model, KeraSkin™ for OECD test guideline 439.
Autorzy :
Han J; College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea.
Kim S; Biosolution Co, Seoul, Republic of Korea.
Lee SH; Biosolution Co, Seoul, Republic of Korea.
Kim JS; COSMAX Korea, Seongnam-si, Republic of Korea.
Chang YJ; Korea Conformity Laboratories, Incheon, Republic of Korea.
Jeong TC; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Kang MJ; College of Pharmacy, Yeungnam University, Gyeongsan, Republic of Korea.
Kim TS; National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Republic of Korea.
Yoon HS; National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Republic of Korea.
Lee GY; National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Osong, Republic of Korea.
Bae S; College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea. Electronic address: .
Lim KM; College of Pharmacy, Ewha Womans University, Seoul, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104725. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Selecting a minimal set of androgen receptor assays for screening chemicals.
Autorzy :
Judson R; U.S. Environmental Protection Agency, RTP, NC, USA. Electronic address: .
Houck K; U.S. Environmental Protection Agency, RTP, NC, USA.
Paul Friedman K; U.S. Environmental Protection Agency, RTP, NC, USA.
Brown J; U.S. Environmental Protection Agency, RTP, NC, USA.
Browne P; OECD, Paris, France.
Johnston PA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.
Close DA; Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA.
Mansouri K; Integrated Laboratory Systems, Inc., Morrisville, NC, USA.
Kleinstreuer N; NTP Interagency Center for the Evaluation of Alternative Toxicological Methods, RTP, NC, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104764. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Weight of evidence and human relevance evaluation of the benfluralin mode of action in rodents (Part I): Liver carcinogenesis.
Autorzy :
Strupp C; Gowan, Highlands House, Basingstoke Road, Spencers Wood, Reading, Berkshire, RG7 1NT, UK. Electronic address: .
Quesnot N; Charles River Laboratories Evreux, 27005, Evreux Cedex, France. Electronic address: .
Richert L; KaLy-Cell, 67115, Plobsheim, France. Electronic address: .
Moore J; Charles River Laboratories Evreux, 27005, Evreux Cedex, France. Electronic address: .
Bomann WH; ToxConsult®, 9393 W 110th Street, 51 Corporate Woods, Suite 500, Overland Park, KS, 66210, USA. Electronic address: .
Singh P; Charles River Laboratories Evreux, 27005, Evreux Cedex, France. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104758. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Dose-response assessment for impaired memory from chronic exposure to domoic acid among native American consumers of razor clams.
Autorzy :
Stuchal LD; Center for Environmental and Human Toxicology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA. Electronic address: .
Grattan LM; Department of Neurology, Neuropsychology Program, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: .
Portier KM; Center for Environmental and Human Toxicology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA. Electronic address: .
Kilmon KA; Department of Neurology, Neuropsychology Program, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address: .
Manahan LM; Washington State Department of Health, Olympia, WA, USA. Electronic address: .
Roberts SM; Center for Environmental and Human Toxicology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA; Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville, FL, USA. Electronic address: .
Morris JG Jr; Emerging Pathogens Institute, University of Florida, and Department of Medicine, College of Medicine, University of Florida, Gainesville, FL, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104759. Date of Electronic Publication: 2020 Aug 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Four-week repeated dose oral toxicity study of KDS2010, a novel selective monoamine oxidase B inhibitor, in Sprague Dawley rats.
Autorzy :
Kim KT; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Kim DH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Kim BK; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Han JS; Department of Advanced Toxicology Research, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Eom HY; Department of Advanced Toxicology Research, Korea Institute of Toxicology (KIT), 141 Gajeong-ro, Yuseong-gu, Daejeon, Republic of Korea.
Yang MJ; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Shin SH; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Cho DW; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea.
Jang BK; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Park KD; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Yang YS; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea. Electronic address: .
Han SC; Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeonbuk, 56212, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104733. Date of Electronic Publication: 2020 Aug 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeks.
Autorzy :
Kale VP; Battelle, Columbus, OH, USA. Electronic address: .
Wallery J; Battelle, Columbus, OH, USA.
Novak J; Battelle, Columbus, OH, USA.
Gibbs S; Battelle, Columbus, OH, USA.
Bourdi M; National Center for Advancing Translational Sciences, National Institute of Health, Bethesda, MD, USA.
Do MT; Lumos Pharma, Austin, TX, USA.
McKew JC; Lumos Pharma, Austin, TX, USA.
Terse PS; National Center for Advancing Translational Sciences, National Institute of Health, Bethesda, MD, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104750. Date of Electronic Publication: 2020 Aug 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Repolarization studies using human stem cell-derived cardiomyocytes: Validation studies and best practice recommendations.
Autorzy :
Gintant G; Department of Integrative Pharmacology, Integrated Sciences and Technology, AbbVie, North Chicago, IL, 60064, USA. Electronic address: .
Kaushik EP; Takeda Pharmaceutical Co, Cambridge, MA, 02139, USA. Electronic address: .
Feaster T; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, 20993, USA. Electronic address: .
Stoelzle-Feix S; Nanion Technologies, Munich, Germany. Electronic address: .
Kanda Y; Division of Pharmacology, National Institute of Health Sciences, Kanagawa, Japan. Electronic address: .
Osada T; LSI Medience Corporation, Tokyo, Japan. Electronic address: .
Smith G; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Scotland, UK; Clyde Biosciences Ltd., Scotland, UK. Electronic address: .
Czysz K; Fujifilm Cellular Dynamics, Inc., Madison, WI, 53711, USA. Electronic address: .
Kettenhofen R; Fraunhofer-Institute for Biomed Engineering IBMT, Sulzbach, Germany. Electronic address: .
Lu HR; Nonclinical Safety, Johnson & Johnson R&D, Beerse, Belgium. Electronic address: .
Cai B; Takeda California, Inc., San Diego, CA, 92121, USA. Electronic address: .
Shi H; Bristol-Myers Squibb, New York, NY, 10016, USA. Electronic address: .
Herron TJ; Frankel Cardiovascular Regeneration Core Laboratory, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: .
Dang Q; Office of Biostatistics, Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, 20993, USA. Electronic address: .
Burton F; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Scotland, UK; Clyde Biosciences Ltd., Scotland, UK. Electronic address: .
Pang L; Division of Systems Biology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, 72079, USA. Electronic address: .
Traebert M; Novartis Inst Biomed Res, Switzerland. Electronic address: .
Abassi Y; Agilent Technologies, San Diego, CA, 92121, USA. Electronic address: .
Pierson JB; Health and Environmental Sciences Institute, Washington, DC, 20005, USA. Electronic address: .
Blinova K; Center for Devices and Radiological Health, US Food and Drug Administration, Silver Spring, MD, 20993, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104756. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis.
Autorzy :
Strupp C; Gowan, Highlands House, Basingstoke Road, Spencers Wood Reading, Berkshire, RG7 1NT, United Kingdom. Electronic address: .
Quesnot N; Charles River Laboratories Evreux, 27005, Evreux Cedex, France. Electronic address: .
Weber-Parmentier C; KaLy-Cell, 67115, Plobsheim, France. Electronic address: .
Richert L; KaLy-Cell, 67115, Plobsheim, France. Electronic address: .
Bomann WH; ToxConsult®, 9393 W 110th Street, 51 Corporate Woods, Suite 500, Overland Park, KS, 66210, USA. Electronic address: .
Singh P; Charles River Laboratories Evreux, 27005, Evreux Cedex, France. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104736. Date of Electronic Publication: 2020 Aug 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Building confidence in skin sensitisation potency assessment using new approach methodologies: report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019.
Autorzy :
Basketter D; DABMEB Consultancy Ltd, Sharnbrook, UK. Electronic address: .
Beken S; European Medicines Agency, Amsterdam, the Netherlands.
Bender H; hjb Consulting, Bonn, Germany.
Bridges J; University of Surrey, Guildford, UK.
Casati S; European Commission, Joint Research Centre (JRC), Ispra, Italy.
Corvaro M; Corteva Agrisciences, Rome, Italy.
Cuvellier S; COSMED, Aix-en-Provence, France.
Hubesch B; Hubesch Consult BVBA, Sint-Pieters-Leeuw, Belgium; European Chemical Industry Council (Cefic), Brussels, Belgium.
Irizar A; The International Fragrance Association (IFRA), Geneva, Switzerland.
Jacobs MN; Public Health England, Chilton, UK.
Kern P; Procter and Gamble Services Company NV/SA, Strombeek-Bever, Belgium.
Lamplmair F; European Commission, Brussels, Belgium.
Manou I; European Partnership for Alternative Approaches to Animal Testing (EPAA), Brussels, Belgium.
Müller BP; Symrise AG, Holzminden, Germany.
Roggeband R; Procter and Gamble Services Company NV/SA, Strombeek-Bever, Belgium.
Rossi LH; European Chemicals Agency, Helsinki, Finland.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104767. Date of Electronic Publication: 2020 Aug 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Iraqi regulatory authority current system and experience with biosimilars.
Autorzy :
Al-Kinani KK; College of Pharmacy, University of Baghdad, Baghdad, Iraq. Electronic address: .
Ibrahim MJ; College of Medicine, University of Baghdad, Baghdad, Iraq.
Al-Zubaidi RF; Directorate of Forensic Medicine, Ministry of Health and Environment, Baghdad, Iraq.
Younus MM; Iraqi Pharmacovigilance Center, Ministry of Health and Environment, Baghdad, Iraq.
Ramadhan SH; National Center for Drug Control and Research, Ministry of Health and Environment, Baghdad, Iraq.
Kadhim HJ; Registration Department, Ministry of Health and Environment, Baghdad, Iraq.
Challand R; Challand Biosimilar Consulting Ltd, United Kingdom.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104768. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Reflections on the OECD guidelines for in vitro skin absorption studies.
Autorzy :
Hopf NB; Centre for Primary Care and Public Health (Unisante), Department for Occupational and Environmental Health (DSTE), Exposure Science Unit, Switzerland. Electronic address: .
Champmartin C; French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS), France. Electronic address: .
Schenk L; Karolinska Institutet, Institute of Environmental Medicine, Unit of Integrative Toxicology, Sweden. Electronic address: .
Berthet A; Centre for Primary Care and Public Health (Unisante), Department for Occupational and Environmental Health (DSTE), Exposure Science Unit, Switzerland. Electronic address: .
Chedik L; French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS), France. Electronic address: .
Du Plessis JL; Occupational Hygiene and Health Research Initiative (OHHRI) North-West University, South Africa. Electronic address: .
Franken A; Occupational Hygiene and Health Research Initiative (OHHRI) North-West University, South Africa. Electronic address: .
Frasch F; Occupational Hygiene and Health Research Initiative (OHHRI) North-West University, South Africa. Electronic address: .
Gaskin S; University of Adelaide, School of Public Health, Health and Medical Sciences, Australia. Electronic address: .
Johanson G; Karolinska Institutet, Institute of Environmental Medicine, Unit of Integrative Toxicology, Sweden. Electronic address: .
Julander A; Karolinska Institutet, Institute of Environmental Medicine, Unit of Integrative Toxicology, Sweden. Electronic address: .
Kasting G; University of Cincinnati, James L. Winkle College of Pharmacy, USA. Electronic address: .
Kilo S; Friedrich-Alexander University Erlangen-Nürnberg, Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Germany. Electronic address: .
Larese Filon F; University of Trieste, Clinical Unit of Occupational Medicine, Department of Medical, Surgical and Health Sciences, Italy. Electronic address: .
Marquet F; French National Research and Safety Institute for the Prevention of Occupational Accidents and Diseases (INRS), France. Electronic address: .
Midander K; Karolinska Institutet, Institute of Environmental Medicine, Unit of Integrative Toxicology, Sweden. Electronic address: .
Reale E; Centre for Primary Care and Public Health (Unisante), Department for Occupational and Environmental Health (DSTE), Exposure Science Unit, Switzerland. Electronic address: .
Bunge AL; Colorado School of Mines, Chemical and Biological Engineering, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104752. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Application of the dermal sensitization threshold concept to chemicals classified as high potency category for skin sensitization assessment of ingredients for consumer products.
Autorzy :
Nishijo T; Safety Science Research Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-3497, Japan. Electronic address: .
Api AM; Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, United States.
Gerberick GF; GF3 Consultancy, LLC, 6592 Pullman Court, West Chester, OH 45069, United States.
Miyazawa M; Safety Science Research Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-3497, Japan.
Roberts DW; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, United Kingdom.
Safford RJ; B-Safe Toxicology Consulting, 31 Hayway, Rushden, Northants, NN10 6AG, United Kingdom.
Sakaguchi H; Safety Science Research Laboratories, Kao Corporation, 2606 Akabane, Ichikai, Haga, Tochigi 321-3497, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104732. Date of Electronic Publication: 2020 Aug 11.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A 26-week toxicological study of Xuezhikang (XZK), red yeast rice extract, in Beagle dogs with a 4-week recovery period.
Autorzy :
Li C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Su C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Wang Y; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Gao Y; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Wang H; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Tian J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
Fu F; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104781. Date of Electronic Publication: 2020 Sep 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Can we define a level of protection for allergic consumers that everyone can accept?
Autorzy :
Madsen CB; Technical University of Denmark, Anker Engelundsvej 1, 2860, Lyngby, Denmark. Electronic address: .
van den Dungen MW; DSM Food Specialties B.V., Alexander Fleminglaan 1, 2613 AX, Delft, Netherlands.
Cochrane S; Unilever SEAC, Colworth Science Park, Sharnbrook, MK44 1LQ, UK.
Houben GF; The Netherlands Organisation for Applied Scientific Research (TNO), Utrecht, Netherlands; Dept. Dermatology/Allergology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Knibb RC; School of Psychology, Aston University, Birmingham, B4 7ET, UK.
Knulst AC; Dept. Dermatology/Allergology and Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands.
Ronsmans S; Coca-Cola Services NV, BE, Belgium.
Yarham RAR; Food Standards Agency (FSA), UK.
Schnadt S; German Allergy and Asthma Association (DAAB), Mönchengladbach, DE, Germany.
Turner PJ; National Heart & Lung Institute, Imperial College London, UK.
Baumert J; University of Nebraska-Lincoln, USA.
Cavandoli E; Barilla G&R Fratelli, Italy.
Chan CH; Food Standards Agency (FSA), UK.
Warner A; Allergy UK, UK.
Crevel RWR; University of Nebraska-Lincoln, USA; René Crevel Consulting Limited, Bedford, MK44 3UE, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2020 Nov; Vol. 117, pp. 104751. Date of Electronic Publication: 2020 Aug 05.
Typ publikacji :
Journal Article
Czasopismo naukowe

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