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Tytuł :
Evidence-based regulations for bioinformatic prediction of allergen cross-reactivity are needed.
Autorzy :
Herman RA; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 47968, USA. Electronic address: .
Song P; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, 47968, USA.
Mirsky HP; Corteva Agriscience, 8325 NW 62nd Avenue, Johnston, IA, 50131, USA.
Roper JM; Corteva Agriscience, P.O. Box 30 Newark DE, 19714, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104841. Date of Electronic Publication: 2020 Dec 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Non-dioxin-like polychlorinated biphenyl neurotoxic equivalents found in environmental and human samples.
Autorzy :
Holland EB; Department of Biological Sciences, California State University of Long Beach, Long Beach, CA, USA. Electronic address: .
Pessah IN; Department of Molecular Biosciences, School of Veterinary Medicine, University of California, Davis, CA, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104842. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of the carcinogenicity of dichloromethane in rats, mice, hamsters and humans.
Autorzy :
Dekant W; Department of Pharmacology and Toxicology, Universität Würzburg, Versbacherstr. 9, 97078 Würzburg, Germany.
Jean P; Olin Corporation, 2205 Ridgewood Dr., Midland, MI, 48642 USA.
Arts J; Nouryon Industrial Chemicals, PO Box 60192, 6800 JD Arnhem, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104858. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Skin immune cell characterization in juvenile and adult Göttingen Minipigs.
Autorzy :
Allais L; Charles River, Saint-Germain-Nuelles, France. Electronic address: .
Brisebard E; Charles River, Saint-Germain-Nuelles, France.
Ravas N; Charles River, Saint-Germain-Nuelles, France.
Briffaux JP; Charles River, Saint-Germain-Nuelles, France.
Pallardy M; Université Paris-Saclay, Inserm, Inflammation, Microbiome and Immunosurveillance, Faculté de Pharmacie, 92290, Châtenay-Malabry, France.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104861. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Autorzy :
Zabka TS; Genentech Inc, 1 DNA Way, South San Francisco, CA, USA. Electronic address: .
Burkhardt J; Pfizer, 1 Eastern Point Road, Groton, CT, USA. Electronic address: .
Reagan WJ; Pfizer, 1 Eastern Point Road, Groton, CT, USA. Electronic address: .
Gautier JC; Sanofi, 13, Quai Jules Guesde, Vitry-sur-Seine, France. Electronic address: .
Glaab WE; Merck & Co, 770 Sumneytown Pike, West Point, PA, USA. Electronic address: .
Guffroy M; AbbVie, 1 North Waukegan Road, North Chicago, IL, USA. Electronic address: .
Harding J; AstraZeneca, Da Vinci Building, Melbourn Science Park, Cambridge Road, Melbourn, Royston, Hertfordshire, UK. Electronic address: .
Brees D; Novartis, 4057 Basel, Basel-stadt, Switzerland. Electronic address: .
McDuffie E; Janssen, 3210 Merryfield Row, San Diego, CA, USA. Electronic address: .
Ramaiah L; Pfizer, 401 North Middletown Road, Pearl River, NY, USA. Electronic address: .
Schultze AE; Lilly Research Laboratories, 893 S Delaware St, Indianapolis, IN, USA. Electronic address: .
Smith JD; Boehringer Ingelheim, 900 Ridgebury Rd, Ridgefield, CT, USA. Electronic address: .
Wolfreys A; UCB Biopharma, Bath Road, Slough, Berkshire, UK. Electronic address: .
Dalmas DA; GlaxoSmithKline, 1250 S. Collegeville Rd, Collegeville, PA, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104857. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling.
Autorzy :
Bercu J; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Masuda-Herrera MJ; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Trejo-Martin A; Gilead Sciences, 333 Lakeside Drive, Foster City, CA, USA.
Hasselgren C; Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
Lord J; Ultragenyx, 60 Leveroni Court, Novato, CA, 94949, USA.
Graham J; Bristol Myers Squibb, 1 Squibb Dr, New Brunswick, NJ, 08903, USA.
Schmitz M; AbbVie Inc., North Chicago, IL, USA.
Milchak L; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
Owens C; 3M Company, 3M Center, St. Paul, MN, 55144-1000, USA.
Lal SH; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Robinson RM; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Whalley S; Syngenta Crop Protection, Product Safety Department, Jealott's Hill International Research Centre, Bracknell, Berkshire, RG42 6EY, UK(1).
Bellion P; DSM Nutritional Products, Kaiseraugst, Switzerland.
Vuorinen A; DSM Nutritional Products, Kaiseraugst, Switzerland.
Gromek K; Galapagos SASU, 102 Avenue Gaston Roussel, 93230, Romainville, France.
Hawkins WA; GlaxoSmithKline, Park Road, Ware, Hertfordshire, SG12 0DP, United Kingdom.
van de Gevel I; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
Vriens K; Janssen Pharmaceutical Companies of Johnson & Johnson, 2340, Beerse, Belgium.
Kemper R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
Naven R; Vertex Pharmaceuticals Inc., Discovery and Investigative Toxicology, 50 Northern Ave, Boston, MA, USA.
Ferrer P; Department of Veterinary Physiology and Pharmacology, Interdisciplinary Faculty of Toxicology Program, Texas A&M University, 4466 TAMU, College Station, TX, 77843-4466, USA.
Myatt GJ; Leadscope (an Instem company), 1393 Dublin Rd, Columbus, OH, 43215, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104843. Date of Electronic Publication: 2020 Dec 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Risk assessment of predicted serum concentrations of bisphenol A in children and adults following treatment with dental composite restoratives, dental sealants, or orthodontic adhesives using physiologically based pharmacokinetic modeling.
Autorzy :
Bagley BD; 3M Corporate Toxicology and Environmental Science, 3M Center, St. Paul, MN, 55144-1000, USA. Electronic address: .
Smith JN; Exposure Science, Pacific Northwest National Laboratory, Richland, WA, 99352, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 93771, USA.
Teeguarden JG; Exposure Science, Pacific Northwest National Laboratory, Richland, WA, 99352, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, 93771, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104839. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Estimation of toluene exposure in air from BMA (S-benzylmercapturic acid) urinary measures using a reverse dosimetry approach based on physiologically pharmacokinetic modeling.
Autorzy :
Tohon H; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada.
Valcke M; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada; Direction de la santé environnementale et de la toxicologie, Institut national de santé publique du Québec, Montréal, Quebec, Canada.
Aranda-Rodriguez R; Exposure and Biomonitoring Division, Environmental Health Sciences and Research Bureau, Health Canada, Ottawa, ON, Canada.
Nong A; Exposure and Biomonitoring Division, Environmental Health Sciences and Research Bureau, Health Canada, Ottawa, ON, Canada.
Haddad S; Department of Environmental and Occupational Health, ESPUM, CReSP, Université de Montréal, C.P. 6128 Succ. Centre-ville, Montreal, Qc, H3C 3J7, Canada. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104860. Date of Electronic Publication: 2021 Jan 03.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A 13-week subchronic toxicity study of a Dioscorea Rhizome water extract in rats.
Autorzy :
Cha SB; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim HS; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Bae JS; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Song SW; Nonclinical Research Center, ChemOn Inc., Yongin, 17162, Republic of Korea.
Lim JO; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea.
Kim JC; College of Veterinary Medicine (BK21 Plus Project Team), Chonnam National University, Gwangju, 61186, Republic of Korea. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104844. Date of Electronic Publication: 2020 Dec 21.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Testing the validity of a proposed dermal cancer slope factor for Benzo[a]pyrene.
Autorzy :
Magee BH; Arcadis U.S., Inc., One Executive Drive, Suite 303, Chelmsford, MA, 01824, United States. Electronic address: .
Forsberg ND; Arcadis U.S., Inc, 855 Route 146, Suite 210, Clifton Park, NY, 12065, United States.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104852. Date of Electronic Publication: 2020 Dec 25.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Comparative In vitro metabolism of purified mogrosides derived from monk fruit extracts.
Autorzy :
Bhusari S; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA. Electronic address: .
Rodriguez C; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA.
Tarka SM Jr; The Tarka Group Inc., 210 N. Old Stonehouse Road, Carlisle, PA, 17015, USA.
Kwok D; BRI Biopharmaceutical Research Inc., 101-8898 Heather St, Vancouver, BC, V6P 3S8, Canada.
Pugh G; The Coca-Cola Company, 1 Coca Cola Plaza NW, Atlanta, GA, 30313, USA.
Gujral J; Tate & Lyle, 5450 Prairie Stone Parkway, Hoffman Estates, IL, 60192, USA.
Tonucci D; Tate & Lyle, 5450 Prairie Stone Parkway, Hoffman Estates, IL, 60192, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104856. Date of Electronic Publication: 2020 Dec 31.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Quantifying bias in epidemiologic studies evaluating the association between acetaminophen use and cancer.
Autorzy :
Schuemie MJ; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA. Electronic address: .
Weinstein R; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA.
Ryan PB; Department of Epidemiology, Janssen Research and Development, Titusville, NJ, USA.
Berlin JA; Department of Epidemiology, Johnson & Johnson, Titusville, NJ, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104866. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Incorporating lines of evidence from New Approach Methodologies (NAMs) to reduce uncertainties in a category based read-across: A case study for repeated dose toxicity.
Autorzy :
Pestana CB; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.
Firman JW; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK.
Cronin MTD; School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104855. Date of Electronic Publication: 2020 Dec 30.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reproductive and developmental toxicity screening study of an acetone extract of rosemary.
Autorzy :
Phipps KR; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK. Electronic address: .
Danielewska-Nikiel B; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Mushonganono J; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Baldwin N; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104840. Date of Electronic Publication: 2020 Dec 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential.
Autorzy :
Jaeschke H; University of Kansas Medical Center, Department of Pharmacology, Toxicology & Therapeutics, Kansas City, KS, USA.
Murray FJ; Murray & Associates, San Jose, CA, USA.
Monnot AD; Cardno ChemRisk, San Fransisco, CA, USA.
Jacobson-Kram D; ToxRox Consulting, McLean, VA, USA.
Cohen SM; University of Nebraska Medical Center, Havlik-Wall Professor of Oncology, Department of Pathology and Microbiology, Omaha, NE, USA.
Hardisty JF; Experimental Pathology Laboratories, Inc., Research Triangle Park, NC, USA.
Atillasoy E; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Hermanowski-Vosatka A; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Kuffner E; Johnson & Johnson Consumer Health, Fort Washington, PA, USA.
Wikoff D; ToxStrategies, Asheville, NC, USA.
Chappell GA; ToxStrategies, Asheville, NC, USA.
Bandara SB; Cardno ChemRisk, San Fransisco, CA, USA.
Deore M; Johnson & Johnson Consumer Products, India.
Pitchaiyan SK; Johnson & Johnson Consumer Products, India.
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Mar; Vol. 120, pp. 104859. Date of Electronic Publication: 2021 Jan 01.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Derivation of Biomonitoring Equivalents for Aluminium for the Interpretation of Population-level Biomonitoring Data.
Autorzy :
Poddalgoda D; Health Canada, Ottawa, ON. Electronic address: .
Hays SM; Summit Toxicology, LLP.
Kirman C; Summit Toxicology, LLP.
Chander N; Health Canada, Ottawa, ON.
Nong A; Health Canada, Ottawa, ON.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 27, pp. 104913. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Safety evaluation of recycling process used to produce recycled pulp for adult paper diapers.
Autorzy :
Ishii S; Chemicals Evaluation and Research Institute, Japan. Electronic address: .
Fukushima A; Chemicals Evaluation and Research Institute, Japan.
Katagiri R; Chemicals Evaluation and Research Institute, Japan.
Sakunaga M; Chemicals Evaluation and Research Institute, Japan.
Kuribara I; Chemicals Evaluation and Research Institute, Japan.
Uchida T; Chemicals Evaluation and Research Institute, Japan.
Wada M; Unicharm Corporation.
Imai S; Unicharm Corporation.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 27, pp. 104909. Date of Electronic Publication: 2021 Feb 27.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Extended One-Generation Reproductive Toxicity (EOGRT) Study of Benzoic Acid in Sprague Dawley Rats.
Autorzy :
Turnbull D; Ramboll US Consulting, Inc., 4350 North Fairfax Drive, Arlington, VA 22203.
Jack MM; American Beverage Association, Science and Regulatory Affairs, 1275 Pennsylvania Ave. NW, Suite 1100, Washington, DC 20004.
Coder PS; Charles River Laboratories Ashland Inc., 1407 George Road, Ashland, OH 44805.
Picut CA; Charles River Laboratories Inc, 4025 Stirrup Creek Dr. Durham, NC 27703.
Rodricks JV; Ramboll US Consulting, Inc., 4350 North Fairfax Drive, Arlington, VA 22203.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 24, pp. 104897. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Comprehensive Analysis of Chronic Rodent Inhalation Toxicity Studies for Methyl Acrylate with Attention to Test Conditions Exceeding a Maximum Tolerated Concentration.
Autorzy :
Wibbertmann A; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625, Hannover, Germany. Electronic address: .
Bitsch A; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Str. 1, 30625, Hannover, Germany.
Kuper CF; Haagstraat 13, 3581 SW, Utrecht, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 23, pp. 104900. Date of Electronic Publication: 2021 Feb 23.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
How Sensitive does Chemical Characterization of Medical Devices Need To Be? Calibration of Analytical Evaluation Thresholds with the Carcinogenic Potency Database.
Autorzy :
Kennedy TA; W.L. Gore & Associates, Inc. P. O. Box 2400, Flagstaff, AZ, 86003-2400, USA. Electronic address: .
Spinti MJ; W.L. Gore & Associates, Inc. P. O. Box 2400, Flagstaff, AZ, 86003-2400, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 20, pp. 104899. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Purification of Bhallathaka (Semecarpus anacardium L.f.) enhanced anti-cancer activity.
Autorzy :
T SC; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India. Electronic address: .
M D; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
K PT; Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, 643001, Tamil Nadu, India.
R LK; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
M AE; Product Development Department, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
M S; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
Balachandran I; Phytochemistry Division, Centre for Medicinal Plants Research, Arya Vaidya Sala, Kottakkal, 676503, Malappuram, Kerala, India.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 20; Vol. 122, pp. 104898. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Harmonized 3Rs-based non-mutagenic impurity qualification study designs developed using the results of an IQ consortium survey.
Autorzy :
Mitra MS; Genentech Inc, Safety Assessment, South San Francisco, CA, USA. Electronic address: .
Datta K; Bristol-Myers Squibb, Nonclinical Research and Development, NJ, USA.
Hutchinson R; Janssen Research & Development, LLC, Spring House, PA, USA.
Nicolette JJ; Abbvie, Inc., Pre-clinical Safety, North Chicago, IL, USA.
Pettersen JC; Vertex Pharmaceuticals, Pre-clinical Safety Assessment Boston, MA, USA.
Wegesser TC; Amgen, Translational Safety and Bioanalytical Sciences, Thousand Oaks, CA, USA.
Bercu JP; Gilead Sciences, Nonclinical Safety and Pathobiology, Foster City, CA, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 19; Vol. 122, pp. 104895. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Regulatory landscape of nanotechnology and nanoplastics from a global perspective.
Autorzy :
Allan J; Joint Institute for Innovation Policy, Belgium.
Belz S; European Commission, Joint Research Centre (JRC), Italy.
Hoeveler A; European Commission, Joint Research Centre (JRC), Italy.
Hugas M; European Food Safety Authority (EFSA), Italy.
Okuda H; National Institute of Health Sciences (NIHS), Japan.
Patri A; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Rauscher H; European Commission, Joint Research Centre (JRC), Italy.
Silva P; Canadian Food Inspection Agency, Canada.
Slikker W; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Sokull-Kluettgen B; European Commission, Joint Research Centre (JRC), Italy.
Tong W; National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA.
Anklam E; European Commission, Joint Research Centre (JRC), Belgium. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 19; Vol. 122, pp. 104885. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Epidemiology of Lung Cancer Among Acrylonitrile-Exposed Study Populations: A Meta-Analysis.
Autorzy :
Alexander DD; MetaMethod, South Lyon, MI. Electronic address: .
Pastula ST; Ann Arbor, MI.
Riordan AS; Chicago, IL.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 19, pp. 104896. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Metribuzin-induced non-adverse liver changes result in rodent-specific non-adverse thyroid effects via uridine 5'-diphospho-glucuronosyltransferase (UDPGT, UGT) modulation.
Autorzy :
Bomann W; Toxconsult, 9393 W 110th Street, 51 Corporate Woods, Suite 500, Overland Park, KS, 66210, USA. Electronic address: .
Tinwell H; Bayer.SAS, 16 rue Jean-Marie Leclair, 69009, Lyon, France.
Jenkinson P; CEHTRA Ltd, Nottingham, UK.
Kluxen FM; ADAMA Deutschland GmbH, Cologne, Germany. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 14; Vol. 122, pp. 104884. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A Comprehensive Weight of Evidence Assessment of Published Acetaminophen Genotoxicity Data: Implications for its Carcinogenic Hazard Potential.
Autorzy :
Kirkland D; Kirkland Consulting, Tadcaster LS24 0AS, UK.
Kovochich M; Cardno ChemRisk, Chicago, IL, USA.
More S; Cardno ChemRisk, Portland, OR, USA.
Murray FJ; Murray & Associates, San Jose, CA, USA.
Monnot AD; Cardno ChemRisk, San Francisco, CA, USA.
Miller J; Cardno ChemRisk, Pittsburgh, PA, USA.
Jaeschke H; University of Kansas Medical Center, Kansas City, KS, USA.
Jacobson-Kram D; ToxRox Consulting, McLean, VA, USA.
Deore M; Johnson & Johnson Consumer, India.
Pitchaiyan SK; Johnson & Johnson Consumer, India.
Unice K; Cardno ChemRisk, Pittsburgh, PA, USA.
Eichenbaum G; Johnson & Johnson, New Brunswick, NJ, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 13, pp. 104892. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vivo safety testing of Antibody Drug Conjugates.
Autorzy :
Pretto F; University of Geneva, Faculty of Medicine, Rue Michel-Servet 1, 1206, Genève, Switzerland. Electronic address: .
FitzGerald RE; University of Basel, Department of Pharmaceutical Sciences, Swiss Centre for Applied Human Toxicology, SCAHT, Missionsstrasse 64, 4055, Basel, Switzerland. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 13; Vol. 122, pp. 104890. Date of Electronic Publication: 2021 Feb 13.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Disease area and mode of action as criteria to assign a default occupational exposure limit.
Autorzy :
Glogovac M; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland. Electronic address: .
Paulson C; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland. Electronic address: .
Lambert A; Novartis Institutes for BioMedical Research, Cambridge, USA; Roche Innovation Center Zurich, Wagistrasse 10, CH-8952, Schlieren, Switzerland. Electronic address: .
Winkler GC; Novartis Pharma AG NIBR, Postfach, CH-4002, Basel, Switzerland; Preclinical Safety Consultant, In den Reben 229, CH-5063, Oberhof, Switzerland. Electronic address: .
Lovsin Barle E; Novartis Pharma AG, Novartis Business Services, Postfach, CH-4002, Basel, Switzerland; Takeda Pharmaceutical Company Limited, Thurgauerstrasse 130, CH-8152, Glattpark (Opfikon), Switzerland. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104891. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Probabilistic pharmacokinetic modeling of airborne lead corresponding to toxicologically relevant blood lead levels in workers.
Autorzy :
Sweeney LM; UES, Inc., assigned to Air Force Research Laboratory, 711th Human Performance Wing, 4401 Dayton-Xenia Road, Dayton, OH, 45432, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104894. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Preclinical safety evaluation of nafithromycin (WCK 4873) with emphasis on liver safety in rat and dog.
Autorzy :
Nandanwar M; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India. Electronic address: .
Chavan R; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Kansagara A; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel MA; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel A; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Yeole R; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
Patel M; Wockhardt Research Centre, Chikalthana, Aurangabad, Maharashtra, India.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104889. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of the OECD QSAR toolbox automatic workflow for the prediction of the acute toxicity of organic chemicals to fathead minnow.
Autorzy :
Mombelli E; Institut National de l'Environnement Industriel et des Risques (INERIS), 60550, Verneuil en Halatte, France. Electronic address: .
Pandard P; Institut National de l'Environnement Industriel et des Risques (INERIS), 60550, Verneuil en Halatte, France.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 12; Vol. 122, pp. 104893. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
In vitro skin penetration of bronidox, bronopol and formaldehyde from cosmetics.
Autorzy :
López-Sánchez L; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain.
Miralles P; Departament of Analytical Chemistry, Faculty of Chemistry. University of Valencia, Valencia, Spain.
Salvador A; Departament of Analytical Chemistry, Faculty of Chemistry. University of Valencia, Valencia, Spain.
Merino-Sanjuán M; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain. Electronic address: .
Merino V; Department of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, Valencia, Spain; Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Av. Vicent Andrés Estellés s/n, 46100, Burjassot, Valencia, Spain.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 09; Vol. 122, pp. 104888. Date of Electronic Publication: 2021 Feb 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Assessment of the toxicity and toxicokinetics of the novel potent tropomyosin receptor kinase (Trk) inhibitor LPM4870108 in rhesus monkeys.
Autorzy :
Duan S; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Dong L; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Wang B; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Wei S; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Gong X; State Key Laboratory of Long-acting Targeting Drug Delivery Technologies (Luye Pharma Group Ltd.), Yantai, 264003, PR China.
Yu P; School of Public Health and Management, Binzhou Medical University, Yantai, 264003, PR China.
Li C; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China.
Gao Y; School of Life Science, Yantai University, Yantai, 264005, PR China.
Ye L; School of Public Health and Management, Binzhou Medical University, Yantai, 264003, PR China.
Wang H; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
Tian J; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, PR China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb 06; Vol. 122, pp. 104886. Date of Electronic Publication: 2021 Feb 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The performance, reliability and potential application of in silico models for predicting the acute oral toxicity of pharmaceutical compounds.
Autorzy :
Graham JC; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA. Electronic address: .
Rodas M; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
Hillegass J; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
Schulze G; Bristol Myers Squibb, 1 Squibb Drive, New Brunswick, NJ, 08903, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104816. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluation of dietary dose administration as an alternative to oral gavage in the rodent uterotrophic and Hershberger assays.
Autorzy :
Markell LK; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA. Electronic address: .
O'Connor JC; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
Luo R; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA.
Klems JP; FMC Corporation, 1090 Elkton Road, Newark, DE, 19711, USA.
Sayers BC; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
Mingoia RT; DuPont Haskell Laboratory, 1090 Elkton Road, Newark, DE, 19711, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104820. Date of Electronic Publication: 2020 Nov 09.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Simple methodology for ensuring the precision of measuring radioactivity at low concentrations in very small tissues using quantitative whole-body autoradiography.
Autorzy :
Hironaka T; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan; Development of Drug Safety & DMPK, Research Area for Candidate Selection, Shionogi TechnoAdvance Research Co., Ltd., Toyonaka, Osaka, Japan. Electronic address: .
Inazawa K; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan; Development of Drug Safety & DMPK, Research Area for Candidate Selection, Shionogi TechnoAdvance Research Co., Ltd., Toyonaka, Osaka, Japan.
Tanaka Y; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan.
Hasegawa H; Drug Metabolism and Pharmacokinetics, Research Laboratory for Development, Shionogi & Co., Ltd., Toyonaka, Osaka, Japan.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104835. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Subchronic toxicity study in rats evaluating herbicide-tolerant soybean DAS-68416-4.
Autorzy :
Zhang L; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Li SF; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Zhou QH; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Liu YH; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Zhang J; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China.
Qian ZY; Department of Toxicology, Tianjin Centers for Disease Control and Prevention, Tianjin, 300011, China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104833. Date of Electronic Publication: 2020 Nov 28.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Antimony release from polyester textiles by artificial sweat solutions: A call for a standardized procedure.
Autorzy :
Biver M; Bibliothèque Nationale du Luxembourg, 37D, Avenue John F. Kennedy, L-1855, Luxembourg, Luxembourg.
Turner A; School of Geography, Earth and Environmental Sciences, University of Plymouth, Drake Circus, Plymouth, PL4 8AA, UK.
Filella M; Department F.-A. Forel, University of Geneva, Boulevard Carl-Vogt 66, CH-1205, Geneva, Switzerland. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104824. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Pharmacokinetics and efficacy of atropine sulfate/obidoxime chloride co-formulation against VX in a guinea pig model.
Autorzy :
Kentrop J; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Savransky V; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Klaassen SD; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
van Groningen T; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Bohnert S; Defense Research and Development Canada - Suffield Research Centre, Casualty Management Section, PO Box 4000 Station Main, Medicine Hat, Alberta, T1A 8K6, Canada.
Cornelissen AS; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands.
Cochrane L; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Barry J; Emergent BioSolutions Inc, 300 Professional Drive, Gaithersburg, MD, 20879, USA.
Joosen MJA; TNO Defence, Safety & Security, CBRN Protection, Lange Kleiweg 137, NL-2288, GJ Rijswijk, the Netherlands. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104823. Date of Electronic Publication: 2020 Nov 16.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Computational identification of preservatives with potential neuronal cytotoxicity.
Autorzy :
Kan HL; Doctoral Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan.
Wang CC; Department and Graduate Institute of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, 106, Taiwan.
Lin YC; Doctoral Degree Program in Toxicology, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan; School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, 807, Taiwan. Electronic address: .
Tung CW; Graduate Institute of Data Science, College of Management, Taipei Medical University, Taipei, 106, Taiwan; National Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli County, 350, Taiwan. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104815. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Genotoxicity and subchronic toxicity studies of supercritical carbon dioxide and acetone extracts of rosemary.
Autorzy :
Phipps KR; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK. Electronic address: .
Lozon D; Intertek Health Sciences Inc, 2233 Argentia Road, Suite 201, Mississauga, Ontario, Canada.
Baldwin N; Intertek Health Sciences Inc, Room 1036, Building A8, Cody Technology Park, Ively Road, Farnborough, Hampshire, UK.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104826. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evaluating chemical similarity as a measure to identify potential substances of very high concern.
Autorzy :
Wassenaar PNH; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands. Electronic address: .
Rorije E; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands.
Vijver MG; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands.
Peijnenburg WJGM; National Institute for Public Health and the Environment (RIVM), P.O. Box 1, 3720BA, Bilthoven, the Netherlands; Institute of Environmental Sciences (CML), Leiden University, P. O. Box 9518, 2300RA, Leiden, the Netherlands.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104834. Date of Electronic Publication: 2020 Nov 20.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A weight of evidence assessment of the genotoxicity of 2,6-xylidine based on existing and new data, with relevance to safety of lidocaine exposure.
Autorzy :
Kirkland DJ; Kirkland Consulting, P O Box 79, Tadcaster, LS24 0AS, United Kingdom. Electronic address: .
Sheil ML; Animal Ethics Pty Ltd., 363 Steeles Road, Yarra Glen, VIC, 3775, Australia.
Streicker MA; Integrated Laboratory Systems, LLC, 635 Davis Drive, Suite 600, Morrisville, NC, 27560, USA.
Johnson GE; Institute of Life Science, Swansea University Medical School, Singleton Park, Swansea, SA3 5DE, United Kingdom.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104838. Date of Electronic Publication: 2020 Dec 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Aloe gel-base food products: Chemical, toxicological, and regulatory aspects.
Autorzy :
Baldi A; Tefarco Innova, National Inter-University Consortium of Innovative Pharmaceutical Technologies, Parco Area delle Scienze 27/A - Campus 43124 Parma, Italy. Electronic address: .
Sommella E; Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy. Electronic address: .
Campiglia P; Department of Pharmacy, University of Salerno, 84084 Fisciano, SA, Italy; European Biomedical Research Institute of Salerno, Via De Renzi 50, I-84125 Salerno, Italy. Electronic address: .
Daglia M; Department of Pharmacy, University of Napoli Federico II, Via D. Montesano 49, 80131, Naples, Italy; International Research Center for Food Nutrition and Safety, Jiangsu University, Zhenjiang 212013, China. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104818. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
A review to support the derivation of a worst-case dermal penetration value for nanoparticles.
Autorzy :
Gimeno-Benito I; Leitat Technological Center, Innovació 2, 08225, Terrassa, Spain.
Giusti A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max- Dohrn- Strasse 8-10, 10589, Berlin, Germany.
Dekkers S; Rijksinstituut voor Volksgezondheid en Milieu (RIVM), P.O. Box 1, 3720, BA, Bilthoven, the Netherlands.
Haase A; German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Max- Dohrn- Strasse 8-10, 10589, Berlin, Germany.
Janer G; Leitat Technological Center, Innovació 2, 08225, Terrassa, Spain. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104836. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Safety assessment of ethanolic root extract of Zaleya decandra (EEZD) in Wistar rats.
Autorzy :
Deivasigamani M; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India.
Kannan N; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India.
Sekar N; Department of Biotechnology, Sri Ramakrishna College of Arts and Science, Coimbatore, 641 006, Tamil Nadu, India.
Lakshmanan H; Department of Biochemistry, Karpagam Academy of Higher Education, Eachanari, Coimbatore, 641 021, Tamil Nadu, India. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104822. Date of Electronic Publication: 2020 Nov 17.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Industry experiences with immune-mediated findings in biotherapeutic nonclinical toxicology studies.
Autorzy :
MacLachlan TK; Department of Preclinical Safety, Novartis Institutes for Biomedical Research, Cambridge, MA, 02139, USA. Electronic address: .
Kronenberg S; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel, 4070, Basel, Switzerland.
Marshall N; Non-Clinical Safety, GlaxoSmithKline, 1250 South Collegeville RD, Collegeville, PA, 19426, USA.
Andrews L; Abbvie Preclinical Safety, Worcester, MA, USA, 01605.
Berens SJ; Investigative Toxicology and Pathology, Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN, 46285, USA.
Brouta F; UCB Biopharma SRL, Non-Clinical Safety Evaluation, 1420, Braine-l'Alleud, Belgium.
Fogal B; Nonclinical Drug Safety, Boehringer Ingelheim Pharmaceuticals Inc, Ridgefield, CT, 06877, USA.
Freebern W; Bristol Myers Squibb, Drug Safety Evaluation, New Brunswick, NJ, 08903, USA.
Herzyk D; Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA.
Kamperschroer C; Pfizer Worldwide Research & Development, Groton, CT, USA.
Kiessling A; Department of Preclinical Safety, Novartis Institutes for Biomedical Research, Basel, Switzerland.
Schneidkraut M; Astellas Discovery Science and Management, 1 Astellas Way, N2.103, Northbrook, IL, 60062, USA.
Maier C; Non-Clinical Safety, GlaxoSmithKline, 1250 South Collegeville RD, Collegeville, PA, 19426, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104825. Date of Electronic Publication: 2020 Nov 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
The activity of methacrylate esters in skin sensitisation test methods II. A review of complementary and additional analyses.
Autorzy :
Kimber I; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104821. Date of Electronic Publication: 2020 Nov 10.
Typ publikacji :
Journal Article; Review
Czasopismo naukowe
Tytuł :
Assessment of the potential allergenicity and toxicity of Pichia proteins in a novel leghemoglobin preparation.
Autorzy :
Reyes TF; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA. Electronic address: .
Chen Y; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Fraser RZ; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Chan T; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
Li X; Impossible Foods Inc., Impossible Foods Inc., 400 Saginaw Drive, Redwood City, CA, 94063, USA.
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104817. Date of Electronic Publication: 2020 Nov 07.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
A retrospective study on EU harmonised classifications for carcinogenicity to guide future research.
Autorzy :
Terry C; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
Yan Z; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
Corvaro M; Corteva Agriscience, 3B Milton Park Square, OX14 4RN, Abingdon, UK. Electronic address: .
Gehen SC; Corteva Agriscience, 9330 Zionsville Road, Indianapolis, IN, USA. Electronic address: .
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Źródło :
Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2021 Feb; Vol. 119, pp. 104800. Date of Electronic Publication: 2020 Oct 28.
Typ publikacji :
Journal Article
Czasopismo naukowe

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