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Wyszukujesz frazę ""Reilly, R Todd"" wg kryterium: Autor


Tytuł :
Recruitment of latent pools of high-avidity CD8 T cells to the antitumor immune response.
Autorzy :
Ercolini, Anne M.
Ladle, Brian H.
Manning, Elizabeth A.
Pfamienstiel, Lukas W.
Armstrong, Todd D.
Machiels, Jean-Pascal H.
Bieler, Joan G.
Emens, Leisha A.
Reilly, R. Todd
Jaffee, Elizabeth M.
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Temat :
T cells
ANTINEOPLASTIC agents
CYCLOPHOSPHAMIDE
IMMUNE response
CANCER vaccines
TUMOR antigens
TRANSGENIC mice
DRUG therapy
Źródło :
Journal of Experimental Medicine; 5/16/2005, Vol. 201 Issue 10, p1591-1602, 12p, 1 Chart, 8 Graphs
Czasopismo naukowe
Tytuł :
213Bi (alpha-emitter)-antibody targeting of breast cancer metastases in the neu-N transgenic mouse model.
Autorzy :
Song H; Divisions of Nuclear Medicine and Neuroradiology, Russell H. Morgan Department of Radiology and Radiological Science, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Shahverdi K
Huso DL
Esaias C
Fox J
Liedy A
Zhang Z
Reilly RT
Apostolidis C
Morgenstern A
Sgouros G
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Źródło :
Cancer research [Cancer Res] 2008 May 15; Vol. 68 (10), pp. 3873-80.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mammary Neoplasms, Animal/*pathology
Mammary Neoplasms, Animal/*radiotherapy
Radioimmunotherapy/*methods
Receptor, ErbB-2/*metabolism
Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal, Murine-Derived ; Kinetics ; Mice ; Mice, Transgenic ; Neoplasm Metastasis ; Neoplasm Transplantation ; Radioimmunotherapy/instrumentation ; Rats ; Receptor, ErbB-2/genetics ; Rituximab ; Spheroids, Cellular/metabolism ; Time Factors ; Tumor Cells, Cultured/metabolism
Czasopismo naukowe
Tytuł :
OX40 costimulation synergizes with GM-CSF whole-cell vaccination to overcome established CD8+ T cell tolerance to an endogenous tumor antigen.
Autorzy :
Murata S; Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Ladle BH
Kim PS
Lutz ER
Wolpoe ME
Ivie SE
Smith HM
Armstrong TD
Emens LA
Jaffee EM
Reilly RT
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2006 Jan 15; Vol. 176 (2), pp. 974-83.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antigens, Neoplasm*
CD8-Positive T-Lymphocytes/*immunology
Cancer Vaccines/*administration & dosage
Glycoproteins/*immunology
Granulocyte-Macrophage Colony-Stimulating Factor/*genetics
Receptors, Tumor Necrosis Factor/*administration & dosage
Animals ; Cancer Vaccines/genetics ; Cell Line, Tumor ; Female ; Immune Tolerance ; Mammary Neoplasms, Experimental/immunology ; Mammary Neoplasms, Experimental/therapy ; Mice ; Mice, Transgenic ; NIH 3T3 Cells ; Peptide Fragments/immunology ; Rats ; Receptor, ErbB-2 ; Receptors, OX40 ; Recombinant Proteins ; T-Lymphocytes, Helper-Inducer/immunology
Czasopismo naukowe
Tytuł :
Ductal access for prevention and therapy of mammary tumors.
Autorzy :
Murata S; Department of Oncology, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, MD 21231, USA.
Kominsky SL
Vali M
Zhang Z
Garrett-Mayer E
Korz D
Huso D
Baker SD
Barber J
Jaffee E
Reilly RT
Sukumar S
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Źródło :
Cancer research [Cancer Res] 2006 Jan 15; Vol. 66 (2), pp. 638-45.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Doxorubicin/*analogs & derivatives
Estrogen Antagonists/*pharmacology
Mammary Neoplasms, Animal/*prevention & control
Polyethylene Glycols/*pharmacology
Tamoxifen/*analogs & derivatives
Animals ; Doxorubicin/administration & dosage ; Doxorubicin/pharmacology ; Drug Administration Routes ; Estrogen Antagonists/administration & dosage ; Female ; Humans ; Mammary Glands, Animal ; Mice ; Mice, Transgenic ; Neoadjuvant Therapy ; Polyethylene Glycols/administration & dosage ; Rats ; Tamoxifen/administration & dosage ; Tamoxifen/pharmacology
Czasopismo naukowe
Tytuł :
Cancer vaccines in combination with multimodality therapy.
Autorzy :
Emens LA; The Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Bunting-Blaustein Cancer Research Building, 1650 Orleans Street, Room 4M90 Baltimore, Maryland 21231-1000, USA. />Reilly RT
Jaffee EM
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Źródło :
Cancer treatment and research [Cancer Treat Res] 2005; Vol. 123, pp. 227-45.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Combined Modality Therapy*/methods
Cancer Vaccines/*therapeutic use
Neoplasms/*therapy
Animals ; Clinical Trials as Topic ; Granulocyte-Macrophage Colony-Stimulating Factor/immunology ; Humans ; Neoplasms/immunology
Czasopismo naukowe
Tytuł :
Sasa health exerts a protective effect on Her2/NeuN mammary tumorigenesis.
Autorzy :
Ren M; Roswell Park Cancer Institute, Buffalo, New York 14263, USA. />Reilly RT
Sacchi N
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Źródło :
Anticancer research [Anticancer Res] 2004 Sep-Oct; Vol. 24 (5A), pp. 2879-84.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Sasa*
Mammary Neoplasms, Experimental/*prevention & control
Phytotherapy/*methods
Receptor, ErbB-2/*genetics
Animals ; Female ; Genes, erbB-2 ; Mammary Glands, Animal/drug effects ; Mammary Glands, Animal/growth & development ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/pathology ; Mice ; Mice, Transgenic ; Neoplasm Metastasis ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł :
BNP-7787 (BioNumerik/Baxter Oncology/Grelan).
Autorzy :
Reilly RT; The Johns Hopkins School of Medicine, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 1650 Orleans Street Room 4M08, Baltimore, MD 21231, USA. reilly@jhmi.edu
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Źródło :
IDrugs : the investigational drugs journal [IDrugs] 2004 Jan; Vol. 7 (1), pp. 64-9.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antiemetics/*therapeutic use
Antineoplastic Agents/*adverse effects
Mesna/*analogs & derivatives
Mesna/*therapeutic use
Vomiting/*chemically induced
Vomiting/*drug therapy
Animals ; Antiemetics/adverse effects ; Antiemetics/pharmacokinetics ; Antiemetics/toxicity ; Clinical Trials, Phase I as Topic ; Clinical Trials, Phase II as Topic ; Clinical Trials, Phase III as Topic ; Humans ; Mesna/adverse effects ; Mesna/pharmacokinetics ; Mesna/toxicity ; Structure-Activity Relationship ; Vomiting/prevention & control
Czasopismo naukowe
Tytuł :
Proper costimulation of tumor-reactive T lymphocytes may provide a key to unlock their antitumor activity.
Autorzy :
Reilly RT; Department of Oncology, The Johns Hopkins School of Medicine; Baltimore, Maryland USA. reilly@jhmi.edu
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Źródło :
Cancer biology & therapy [Cancer Biol Ther] 2003 Sep-Oct; Vol. 2 (5), pp. 587-8.
Typ publikacji :
Comment; Editorial
MeSH Terms :
Lymphocyte Activation*
Bone Neoplasms/*immunology
Sarcoma, Ewing/*immunology
T-Lymphocytes/*immunology
T-Lymphocytes, Cytotoxic/*immunology
Tumor Necrosis Factor-alpha/*metabolism
4-1BB Ligand ; Animals ; Bone Neoplasms/prevention & control ; Dendritic Cells/immunology ; Humans ; Mice ; Sarcoma, Ewing/prevention & control
Opinia redakcyjna
Tytuł :
HER-2/neu-specific monoclonal antibodies collaborate with HER-2/neu-targeted granulocyte macrophage colony-stimulating factor secreting whole cell vaccination to augment CD8+ T cell effector function and tumor-free survival in Her-2/neu-transgenic mice.
Autorzy :
Wolpoe ME; Department of Otolaryngology-Head and Neck Surgery, Graduate Program in Immunology, Johns Hopkins School of Medicine, Baltimore, MD 21231, USA.
Lutz ER
Ercolini AM
Murata S
Ivie SE
Garrett ES
Emens LA
Jaffee EM
Reilly RT
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2003 Aug 15; Vol. 171 (4), pp. 2161-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Antibodies, Monoclonal/*therapeutic use
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
CD8-Positive T-Lymphocytes/*immunology
Cancer Vaccines/*immunology
Epitopes, T-Lymphocyte/*genetics
Granulocyte-Macrophage Colony-Stimulating Factor/*metabolism
Mammary Neoplasms, Experimental/*prevention & control
Receptor, ErbB-2/*genetics
3T3 Cells ; Adjuvants, Immunologic/administration & dosage ; Adjuvants, Immunologic/therapeutic use ; Animals ; Antibodies, Monoclonal/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Cancer Vaccines/administration & dosage ; Cancer Vaccines/genetics ; Cell Line ; Cytotoxicity, Immunologic/genetics ; Cytotoxicity, Immunologic/immunology ; Epitopes, T-Lymphocyte/biosynthesis ; Epitopes, T-Lymphocyte/immunology ; Female ; Immunization Schedule ; Injections, Subcutaneous ; Lymphocyte Count ; Mammary Neoplasms, Experimental/immunology ; Mammary Neoplasms, Experimental/metabolism ; Mammary Neoplasms, Experimental/mortality ; Mice ; Mice, Transgenic ; Rats ; Receptor, ErbB-2/biosynthesis ; Receptor, ErbB-2/immunology ; Receptor, ErbB-2/metabolism ; Survival Analysis ; Ubiquitins/metabolism ; Up-Regulation/genetics ; Up-Regulation/immunology
Czasopismo naukowe
Tytuł :
Identification and characterization of the immunodominant rat HER-2/neu MHC class I epitope presented by spontaneous mammary tumors from HER-2/neu-transgenic mice.
Autorzy :
Ercolini AM; Department of Oncology, Sidney Kimmel Cancer Center at Johns Hopkins, Graduate Program in Immunology, The Johns Hopkins School of Medicine, Baltimore, MD 21231, USA.
Machiels JP
Chen YC
Slansky JE
Giedlen M
Reilly RT
Jaffee EM
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2003 Apr 15; Vol. 170 (8), pp. 4273-80.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Antigen Presentation*/genetics
Genes, erbB-2/*immunology
H-2 Antigens/*metabolism
Immunodominant Epitopes/*isolation & purification
Immunodominant Epitopes/*metabolism
Mammary Neoplasms, Experimental/*immunology
3T3 Cells ; Adoptive Transfer ; Animals ; Cell Line, Transformed ; Clone Cells ; Epitopes, T-Lymphocyte/administration & dosage ; Epitopes, T-Lymphocyte/biosynthesis ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/immunology ; Graft Rejection/genetics ; Graft Rejection/immunology ; Growth Inhibitors/administration & dosage ; Growth Inhibitors/biosynthesis ; Growth Inhibitors/genetics ; Growth Inhibitors/immunology ; H-2 Antigens/genetics ; H-2 Antigens/immunology ; H-2 Antigens/isolation & purification ; Histocompatibility Antigen H-2D ; Humans ; Immunodominant Epitopes/genetics ; Injections, Intravenous ; Mammary Neoplasms, Experimental/genetics ; Mammary Neoplasms, Experimental/pathology ; Mammary Neoplasms, Experimental/prevention & control ; Mice ; Mice, Inbred Strains ; Mice, Transgenic ; Peptide Fragments/administration & dosage ; Peptide Fragments/biosynthesis ; Peptide Fragments/genetics ; Peptide Fragments/immunology ; Peptide Mapping ; Rats ; T-Lymphocyte Subsets/immunology ; T-Lymphocyte Subsets/metabolism ; T-Lymphocyte Subsets/transplantation ; Vaccines, DNA/administration & dosage ; Vaccines, DNA/genetics ; Vaccines, DNA/immunology
Czasopismo naukowe

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