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Wyszukujesz frazę ""Reperfusion Injury"" wg kryterium: Temat


Tytuł :
Dexmedetomidine pretreatment attenuates myocardial ischemia reperfusion induced acute kidney injury and endoplasmic reticulum stress in human and rat.
Autorzy :
Tang C; Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui, China. Electronic address: .
Hu Y; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Gao J; Department of Anesthesia, Critical Care & Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02144, USA.
Jiang J; Department of Emergency, Huashan Hospital North, Fudan University, Shanghai, 201907, China.
Shi S; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, China.
Wang J; Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui, China.
Geng Q; Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui, China.
Liang X; Department of Clinical Laboratory, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230000, Anhui, China.
Chai X; Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, Anhui, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Sep 15; Vol. 257, pp. 118004. Date of Electronic Publication: 2020 Jul 02.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Dexmedetomidine/*pharmacology
Myocardial Ischemia/*drug therapy
Myocardial Reperfusion Injury/*drug therapy
Acute Kidney Injury/metabolism ; Acute Kidney Injury/prevention & control ; Aged ; Animals ; Apoptosis/drug effects ; China ; Dexmedetomidine/metabolism ; Endoplasmic Reticulum Stress/drug effects ; Endoplasmic Reticulum Stress/physiology ; Female ; Humans ; Ischemia/metabolism ; Kidney/drug effects ; Male ; Middle Aged ; Myocardial Ischemia/metabolism ; Myocardial Reperfusion/methods ; Myocardial Reperfusion Injury/pathology ; Myocardium/metabolism ; Oxidative Stress/drug effects ; Prospective Studies ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
The Future of Cardioprotection-Pointing Toward Patients at Elevated Risk as the Target Populations.
Autorzy :
Bøtker HE; Department of Cardiology, 11297Aarhus University Hospital, Aarhus, Denmark.
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Źródło :
Journal of cardiovascular pharmacology and therapeutics [J Cardiovasc Pharmacol Ther] 2020 Nov; Vol. 25 (6), pp. 487-493. Date of Electronic Publication: 2020 Jun 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Ischemic Postconditioning*/adverse effects
Ischemic Preconditioning, Myocardial*/adverse effects
Coronary Artery Bypass/*adverse effects
Myocardial Reperfusion Injury/*prevention & control
Percutaneous Coronary Intervention/*adverse effects
Animals ; Humans ; Myocardial Reperfusion Injury/diagnosis ; Myocardial Reperfusion Injury/etiology ; Protective Factors ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Parameters predicting COVID-19-induced myocardial injury and mortality.
Autorzy :
Duerr GD; Department of Cardiovascular Surgery, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Heine A; Department of Internal Medicine III for Hematology, Oncology, Rheumatology and Immune-Oncology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Hamiko M; Department of Cardiovascular Surgery, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Zimmer S; Department of Internal Medicine II - Cardiology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Luetkens JA; Department of Radiology, Quantitative Imaging Lab Bonn (QILaB), University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Nattermann J; Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Rieke G; Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Isaak A; Department of Radiology, Quantitative Imaging Lab Bonn (QILaB), University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Jehle J; Department of Internal Medicine II - Cardiology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Held SAE; Department of Internal Medicine III for Hematology, Oncology, Rheumatology and Immune-Oncology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Wasmuth JC; Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Wittmann M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Strassburg CP; Department of Internal Medicine I, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Brossart P; Department of Internal Medicine III for Hematology, Oncology, Rheumatology and Immune-Oncology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Coburn M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Treede H; Department of Cardiovascular Surgery, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Nickenig G; Department of Internal Medicine II - Cardiology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany.
Kurts C; Institute for Experimental Immunology, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany. Electronic address: .
Velten M; Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, University of Bonn, Venusberg Campus 1, 53127 Bonn, Germany. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118400. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Betacoronavirus/*isolation & purification
Biomarkers/*analysis
Coronavirus Infections/*mortality
Myocardial Reperfusion Injury/*diagnosis
Myocardial Reperfusion Injury/*mortality
Myocardium/*pathology
Pneumonia, Viral/*mortality
Risk Assessment/*methods
Aged ; Coronavirus Infections/complications ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Female ; Germany/epidemiology ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Myocardial Reperfusion Injury/epidemiology ; Myocardial Reperfusion Injury/virology ; Myocardium/metabolism ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Prognosis ; Risk Factors ; Survival Rate
SCR Disease Name :
COVID-19
Czasopismo naukowe
Tytuł :
Short-term molecular and cellular effects of ischemia/reperfusion on vascularized lymph node flaps in rats.
Autorzy :
Frueh FS; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Jelvani B; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
Scheuer C; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
Körbel C; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
Kim BS; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Giovanoli P; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Lindenblatt N; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Harder Y; Department of Plastic, Reconstructive and Aesthetic Surgery, Ente Ospedaliero Cantonale (EOC), Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland.
Ampofo E; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
Menger MD; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
Laschke MW; Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Saar, Germany.
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Źródło :
PloS one [PLoS One] 2020 Oct 06; Vol. 15 (10), pp. e0239517. Date of Electronic Publication: 2020 Oct 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Surgical Flaps*
Lymph Nodes/*blood supply
Lymph Nodes/*surgery
Reperfusion Injury/*pathology
Reperfusion Injury/*physiopathology
Animals ; Apoptosis ; Lymph Nodes/cytology ; Microvessels/physiopathology ; Oxidative Stress ; Rats ; Reperfusion Injury/immunology ; Reperfusion Injury/surgery
Czasopismo naukowe
Tytuł :
Overexpression of miR-217-5p protects against oxygen-glucose deprivation/reperfusion-induced neuronal injury via inhibition of PTEN.
Autorzy :
Yi Z; Department of Central Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, West Xindu Road 2#, Yancheng, 224001, Jiangsu, People's Republic of China.
Shi Y; Department of Central Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, West Xindu Road 2#, Yancheng, 224001, Jiangsu, People's Republic of China.
Zhao P; Department of Central Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, West Xindu Road 2#, Yancheng, 224001, Jiangsu, People's Republic of China.
Xu Y; Department of Neurology, Drum Tower Hospital, Medical School of Nanjing University, Zhongshan Road 321#, Nanjing, 210008, Jiangsu, People's Republic of China. .
Pan P; Department of Central Laboratory, Affiliated Yancheng Hospital, School of Medicine, Southeast University, West Xindu Road 2#, Yancheng, 224001, Jiangsu, People's Republic of China. .; Department of Neurology, Affiliated Yancheng Hospital, School of Medicine, Southeast University, West Xindu Road 2#, Yancheng, 224001, Jiangsu, People's Republic of China. .
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Źródło :
Human cell [Hum Cell] 2020 Oct; Vol. 33 (4), pp. 1026-1035. Date of Electronic Publication: 2020 Jul 18.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression/*genetics
Glucose/*metabolism
MicroRNAs/*genetics
MicroRNAs/*metabolism
MicroRNAs/*physiology
Neurons/*pathology
Oxygen/*metabolism
PTEN Phosphohydrolase/*genetics
PTEN Phosphohydrolase/*metabolism
Reperfusion Injury/*genetics
Up-Regulation/*genetics
Cells, Cultured ; DNA Methylation ; Humans ; Molecular Targeted Therapy ; Reperfusion Injury/etiology ; Reperfusion Injury/therapy
Czasopismo naukowe
Tytuł :
Targeted pharmacotherapy for ischemia reperfusion injury in acute myocardial infarction.
Autorzy :
Rout A; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health , Baltimore, MD, USA.
Tantry US; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health , Baltimore, MD, USA.
Novakovic M; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health , Baltimore, MD, USA.
Sukhi A; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health , Baltimore, MD, USA.
Gurbel PA; Sinai Center for Thrombosis Research and Drug Development, Sinai Hospital of Baltimore, Lifebridge Health , Baltimore, MD, USA.
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Źródło :
Expert opinion on pharmacotherapy [Expert Opin Pharmacother] 2020 Oct; Vol. 21 (15), pp. 1851-1865. Date of Electronic Publication: 2020 Jul 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Anti-Inflammatory Agents/*therapeutic use
Cardiotonic Agents/*therapeutic use
Myocardial Infarction/*drug therapy
Myocardial Reperfusion Injury/*drug therapy
Platelet Aggregation Inhibitors/*therapeutic use
Animals ; Anti-Inflammatory Agents/administration & dosage ; Cardiotonic Agents/administration & dosage ; Humans ; Molecular Targeted Therapy ; Myocardial Infarction/blood ; Myocardial Infarction/complications ; Myocardial Infarction/immunology ; Myocardial Reperfusion Injury/blood ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/immunology ; Platelet Aggregation Inhibitors/administration & dosage
Czasopismo naukowe
Tytuł :
Prokineticin 2 relieves hypoxia/reoxygenation-induced injury through activation of Akt/mTOR pathway in H9c2 cardiomyocytes.
Autorzy :
Su G; Department of Cardiac Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Sun G; Department of Ophthalmology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liu H; Department of Cardiac Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shu L; Department of Cardiac Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang W; Department of Cardiac Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Liang Z; Department of Cardiac Surgery, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 345-352.
Typ publikacji :
Journal Article; Video-Audio Media
MeSH Terms :
Signal Transduction*
Gastrointestinal Hormones/*metabolism
Myocardial Reperfusion Injury/*metabolism
Myocytes, Cardiac/*metabolism
Neuropeptides/*metabolism
Proto-Oncogene Proteins c-akt/*metabolism
TOR Serine-Threonine Kinases/*metabolism
Animals ; Cell Line ; Gastrointestinal Hormones/genetics ; Myocardial Reperfusion Injury/genetics ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/pathology ; Neuropeptides/genetics ; Oxidative Stress ; Proto-Oncogene Proteins c-akt/genetics ; Rats ; TOR Serine-Threonine Kinases/genetics
Czasopismo naukowe
Tytuł :
Circular RNA cZNF292 silence alleviates OGD/R-induced injury through up-regulation of miR-22 in rat neural stem cells (NSCs).
Autorzy :
Cao Y; Neonatal Intensive Care Unit, Zhoukou Central Hospital, Zhoukou, China.
Liu H; Neonatal Intensive Care Unit, Zhoukou Central Hospital, Zhoukou, China.
Zhang J; Neonatal Intensive Care Unit, Zhoukou Central Hospital, Zhoukou, China.
Dong Y; Neonatal Intensive Care Unit, Zhoukou Central Hospital, Zhoukou, China.
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Źródło :
Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2020 Dec; Vol. 48 (1), pp. 594-601.
Typ publikacji :
Journal Article
MeSH Terms :
RNA Interference*
MicroRNAs/*genetics
Neural Stem Cells/*metabolism
RNA, Circular/*genetics
Reperfusion Injury/*prevention & control
Animals ; Apoptosis ; Cell Survival ; Cells, Cultured ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Gene Expression Regulation ; Glucose/metabolism ; MicroRNAs/antagonists & inhibitors ; MicroRNAs/metabolism ; Neural Stem Cells/pathology ; Oxygen/metabolism ; Protein Kinase C/metabolism ; Rats ; Reperfusion Injury/genetics ; Reperfusion Injury/metabolism ; Signal Transduction ; Wnt3A Protein/metabolism ; beta Catenin/metabolism
Czasopismo naukowe
Tytuł :
MiR-29a-3p Enhances the Viability of Rat Neuronal Cells that Injured by Oxygen-Glucose Deprivation/Reoxygenation Treatment Through Targeting TNFRSF1A and Regulating NF-κB Signaling Pathway.
Autorzy :
Gao XZ; Department of Anesthesiology, Affiliated Hospital of North China University of Science and Technology, Tangshan, Hebei 063000, P.R. China.
Zhang ZX; Department of Geriatrics, Shanxian centrol Hospital, Heze, Shandong 274300, P.R. China.
Han GL; Department of Neurosurgery, Shengli Oilfield Central Hospital of Binzhou Medical College, Dongying, Shandong 257034, P.R. China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Nov; Vol. 29 (11), pp. 105210. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
MicroRNAs/*metabolism
NF-kappa B/*metabolism
Neurons/*metabolism
Receptors, Tumor Necrosis Factor, Type I/*metabolism
Reperfusion Injury/*metabolism
Animals ; Apoptosis ; Cell Hypoxia ; Cell Proliferation ; Cell Survival ; Databases, Genetic ; Glucose/deficiency ; Humans ; MicroRNAs/genetics ; Neurons/pathology ; PC12 Cells ; Phosphorylation ; Rats ; Receptors, Tumor Necrosis Factor, Type I/genetics ; Reperfusion Injury/genetics ; Reperfusion Injury/pathology ; Signal Transduction ; Up-Regulation
Czasopismo naukowe
Tytuł :
Milrinone Attenuates Heart and Lung Remote Injury after Abdominal Aortic Cross-Clamping.
Autorzy :
Ak E; Department of Basic Medical Sciences, Department of Histology and Embryology, Marmara University, Faculty of Dentistry, Istanbul, Turkey. Electronic address: .
Ak K; Department of Cardiovascular Surgery, Marmara University, Faculty of Medicine, Istanbul, Turkey.
Ustandag UV; Department of Basic Medical Sciences, Department of Biochemistry, Marmara University, Faculty of Dentistry, Istanbul, Turkey.
Kervancioglu-Demirci E; Department of Histology and Embryology, Istanbul University, Faculty of Medicine, Istanbul, Turkey.
Emekli-Alturfan E; Department of Basic Medical Sciences, Department of Biochemistry, Marmara University, Faculty of Dentistry, Istanbul, Turkey.
Çetinel S; Department of Histology and Embryology, Istanbul University, Faculty of Medicine, Istanbul, Turkey.
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Źródło :
Annals of vascular surgery [Ann Vasc Surg] 2020 Nov; Vol. 69, pp. 391-399. Date of Electronic Publication: 2020 Jun 27.
Typ publikacji :
Journal Article
MeSH Terms :
Aorta, Abdominal/*surgery
Heart/*drug effects
Lung/*drug effects
Lung Injury/*prevention & control
Milrinone/*pharmacology
Myocardial Reperfusion Injury/*prevention & control
Phosphodiesterase 3 Inhibitors/*pharmacology
Animals ; Antioxidants/pharmacology ; Caveolin 1/metabolism ; Caveolin 3/metabolism ; Constriction ; Disease Models, Animal ; Lung/metabolism ; Lung/ultrastructure ; Lung Injury/metabolism ; Lung Injury/pathology ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Myocardium/metabolism ; Myocardium/ultrastructure ; Oxidative Stress/drug effects ; Rats, Wistar ; Signal Transduction
Czasopismo naukowe
Tytuł :
Exosomes from MSCs overexpressing microRNA-223-3p attenuate cerebral ischemia through inhibiting microglial M1 polarization mediated inflammation.
Autorzy :
Zhao Y; School of Clinical Sciences, Hangzhou Medical College, Zhejiang, China.
Gan Y; School of Pharmaceutical Sciences, Hangzhou Medical College, Zhejiang, China.
Xu G; School of Clinical Sciences, Hangzhou Medical College, Zhejiang, China.
Hua K; School of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Zhejiang, China.
Liu D; School of Basic Medical Sciences & Forensic Medicine, Hangzhou Medical College, Zhejiang, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 Nov 01; Vol. 260, pp. 118403. Date of Electronic Publication: 2020 Sep 11.
Typ publikacji :
Journal Article
MeSH Terms :
Brain Ischemia/*prevention & control
Exosomes/*genetics
Inflammation/*prevention & control
MicroRNAs/*genetics
Microglia/*metabolism
Reperfusion Injury/*prevention & control
Animals ; Brain Ischemia/etiology ; Brain Ischemia/metabolism ; Brain Ischemia/pathology ; Infarction, Middle Cerebral Artery/complications ; Inflammation/etiology ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Microglia/immunology ; Microglia/pathology ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/etiology ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology
Czasopismo naukowe
Tytuł :
Neutrophil Elastase Inhibitor Sivelestat Attenuates Myocardial Injury after Cardioplegic Arrest in Rat Hearts.
Autorzy :
Fujii M; Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
Bessho R; Cardiovascular Surgery, Nippon Medical School Chiba Hokusoh Hospital, Inzai, Chiba, Japan.
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Źródło :
Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia [Ann Thorac Cardiovasc Surg] 2020 Oct 21; Vol. 26 (5), pp. 263-269. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article
MeSH Terms :
Glycine/*analogs & derivatives
Heart Arrest, Induced/*adverse effects
Leukocyte Elastase/*antagonists & inhibitors
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*drug effects
Serine Proteinase Inhibitors/*pharmacology
Sulfonamides/*pharmacology
Animals ; Disease Models, Animal ; Glycine/pharmacology ; Isolated Heart Preparation ; Leukocyte Elastase/metabolism ; Male ; Myocardial Reperfusion Injury/enzymology ; Myocardial Reperfusion Injury/pathology ; Myocardial Reperfusion Injury/physiopathology ; Myocytes, Cardiac/enzymology ; Myocytes, Cardiac/pathology ; Rats, Wistar ; Troponin T/metabolism ; Ventricular Function, Left/drug effects ; Ventricular Pressure/drug effects
Czasopismo naukowe
Tytuł :
Early antihypertensive treatment and ischemia-induced acute kidney injury.
Autorzy :
Greite R; Nephrology, Hannover Medical School, Hannover, Germany.
Derlin K; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Hensen B; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Thorenz A; Nephrology, Hannover Medical School, Hannover, Germany.
Rong S; Nephrology, Hannover Medical School, Hannover, Germany.
Chen R; Nephrology, Hannover Medical School, Hannover, Germany.
Hellms S; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Jang MS; Nephrology, Hannover Medical School, Hannover, Germany.
Bräsen JH; Pathology, Hannover Medical School, Hannover, Germany.
Meier M; Imaging Center, Institute of Laboratory Animal Sciences, Hannover Medical School, Hannover, Germany.
Willenberg I; Faculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.
Immenschuh S; Transfusion Medicine, Hannover Medical School, Hannover, Germany.
Haller H; Nephrology, Hannover Medical School, Hannover, Germany.
Luft FC; Experimental and Clinical Research Center, Max-Delbrück Center/Charité, Berlin, Germany.
Panigrahy D; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Hwang SH; Department of Entomology and Nematology, UC Davis Comprehensive Cancer Center, University of California, Davis, California.
Hammock BD; Department of Entomology and Nematology, UC Davis Comprehensive Cancer Center, University of California, Davis, California.
Schebb NH; Faculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany.
Gueler F; Nephrology, Hannover Medical School, Hannover, Germany.
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Źródło :
American journal of physiology. Renal physiology [Am J Physiol Renal Physiol] 2020 Oct 01; Vol. 319 (4), pp. F563-F570. Date of Electronic Publication: 2020 Aug 17.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Kidney Injury/*drug therapy
Antihypertensive Agents/*pharmacology
Blood Pressure/*drug effects
Enzyme Inhibitors/*pharmacology
Glomerulonephritis/*prevention & control
Hypertension/*drug therapy
Phenylurea Compounds/*pharmacology
Piperidines/*pharmacology
Reperfusion Injury/*drug therapy
Acute Kidney Injury/etiology ; Acute Kidney Injury/pathology ; Acute Kidney Injury/physiopathology ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Animals ; Antihypertensive Agents/toxicity ; Disease Models, Animal ; Disease Progression ; Enalapril/pharmacology ; Enzyme Inhibitors/toxicity ; Epoxide Hydrolases/antagonists & inhibitors ; Fibrosis ; Glomerular Mesangium/drug effects ; Glomerular Mesangium/pathology ; Glomerular Mesangium/physiopathology ; Glomerulonephritis/etiology ; Glomerulonephritis/pathology ; Glomerulonephritis/physiopathology ; Hypertension/etiology ; Hypertension/physiopathology ; Male ; Mice ; Phenylurea Compounds/toxicity ; Piperidines/toxicity ; Reperfusion Injury/complications ; Reperfusion Injury/physiopathology
Czasopismo naukowe
Tytuł :
Systematic analysis of different pluripotent stem cell-derived cardiac myocytes as potential testing model for cardiocytoprotection.
Autorzy :
Pálóczi J; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary.
Szántai Á; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary.
Kobolák J; Biotalentum Ltd., Gödöllő, 2100 Hungary.
Bock I; Biotalentum Ltd., Gödöllő, 2100 Hungary.
Ruivo E; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary.
Kiss B; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, 1085 Hungary.
Gáspár R; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary.
Pipis J; Pharmahungary Group, Szeged, 6722 Hungary.
Ocsovszki I; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary.
Táncos Z; Biotalentum Ltd., Gödöllő, 2100 Hungary.
Fehér A; Biotalentum Ltd., Gödöllő, 2100 Hungary.
Dinnyés A; Biotalentum Ltd., Gödöllő, 2100 Hungary; Molecular Animal Biotechnology Laboratory, Szent István University, Gödöllő, 2100 Hungary.
Onódi Z; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, 1085 Hungary.
Madonna R; Institute of Cardiology, Department of Surgical, Medical and Molecular Pathology and Critical Area Medicine, University of Pisa, 56124 Pisa; Internal Medicine, Cardiology Division, University of Texas Medical School in Houston, Houston, Texas.
Ferdinandy P; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary; Pharmahungary Group, Szeged, 6722 Hungary; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, 1085 Hungary; Cardiovascular Research Group, Department of Pharmacology and Pharmacotherapy, University of Szeged, 6720, Hungary.
Görbe A; Cardiovascular Research Group, Department of Biochemistry, University of Szeged, 6720 Hungary; Pharmahungary Group, Szeged, 6722 Hungary; MTA-SE System Pharmacology Research Group, Department of Pharmacology and Pharmacotherapy, Semmelweis University, Budapest, 1085 Hungary; Cardiovascular Research Group, Department of Pharmacology and Pharmacotherapy, University of Szeged, 6720, Hungary. Electronic address: .
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Źródło :
Vascular pharmacology [Vascul Pharmacol] 2020 Oct - Nov; Vol. 133-134, pp. 106781. Date of Electronic Publication: 2020 Aug 19.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Differentiation*
Myocardial Reperfusion Injury/*prevention & control
Myocytes, Cardiac/*drug effects
Nitric Oxide Donors/*pharmacology
Pluripotent Stem Cells/*drug effects
S-Nitroso-N-Acetylpenicillamine/*pharmacology
Cell Line ; Cell Survival/drug effects ; Humans ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/pathology ; Oxidative Stress/drug effects ; Phenotype ; Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/pathology ; Troponin I/metabolism ; Vascular Cell Adhesion Molecule-1/metabolism
Czasopismo naukowe
Tytuł :
Lysophosphatidic acid increased infarct size in the early stage of cerebral ischemia-reperfusion with increased BBB permeability.
Autorzy :
Chi OZ; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA. Electronic address: .
Mellender SJ; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Kiss GK; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Chiricolo A; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Liu X; Department of Anesthesiology and Perioperative Medicine, Rutgers Robert Wood Johnson Medical School, 125 Paterson Street, Suite 3100, New Brunswick, NJ 08901-1977, USA.
Patel N; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
Jacinto E; Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
Weiss HR; Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 675 Hoes Lane West, Piscataway, NJ 08854, USA.
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105029. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Reperfusion*
Blood-Brain Barrier/*drug effects
Capillary Permeability/*drug effects
Cerebral Cortex/*drug effects
Infarction, Middle Cerebral Artery/*therapy
Lysophospholipids/*toxicity
Reperfusion Injury/*chemically induced
Animals ; Blood-Brain Barrier/physiopathology ; Cerebral Cortex/enzymology ; Cerebral Cortex/pathology ; Disease Models, Animal ; Infarction, Middle Cerebral Artery/enzymology ; Infarction, Middle Cerebral Artery/pathology ; Infarction, Middle Cerebral Artery/physiopathology ; Male ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Rats, Inbred F344 ; Reperfusion Injury/enzymology ; Reperfusion Injury/pathology ; Reperfusion Injury/physiopathology ; Ribosomal Protein S6 Kinases/metabolism
Czasopismo naukowe
Tytuł :
Long Non-Coding KCNQ1OT1 Promotes Oxygen-Glucose-Deprivation/Reoxygenation-Induced Neurons Injury Through Regulating MIR-153-3p/FOXO3 Axis.
Autorzy :
Wang HJ; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China; Department of Neurosurgery, Hospital of Guangzhou University Mega Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510006, China.
Tang XL; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Huang G; Postdoctoral Center, Yangjiang Hospital of Chinese Medicine, Yangjiang 529500, China.
Li YB; Department of Neurosurgery, Hospital of Guangzhou University Mega Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510006, China.
Pan RH; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Zhan J; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China.
Wu YK; Postdoctoral Center, Yangjiang Hospital of Chinese Medicine, Yangjiang 529500, China.
Liang JF; Postdoctoral Center, Yangjiang Hospital of Chinese Medicine, Yangjiang 529500, China.
Bai XX; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China; Department of Neurosurgery, Hospital of Guangzhou University Mega Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510006, China. Electronic address: .
Cai J; Diagnosis and Treatment Center of Encephalopathy, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China; Department of Neurosurgery, Hospital of Guangzhou University Mega Center, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510006, China. Electronic address: .
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Źródło :
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association [J Stroke Cerebrovasc Dis] 2020 Oct; Vol. 29 (10), pp. 105126. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article
MeSH Terms :
Cerebral Cortex/*metabolism
Forkhead Box Protein O3/*metabolism
Infarction, Middle Cerebral Artery/*therapy
MicroRNAs/*metabolism
Neurons/*metabolism
RNA, Long Noncoding/*metabolism
Reperfusion/*adverse effects
Reperfusion Injury/*metabolism
Animals ; Cell Hypoxia ; Cells, Cultured ; Cerebral Cortex/pathology ; Forkhead Box Protein O3/genetics ; Gene Expression Regulation ; Glucose/deficiency ; Infarction, Middle Cerebral Artery/genetics ; Infarction, Middle Cerebral Artery/metabolism ; Infarction, Middle Cerebral Artery/pathology ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Neurons/pathology ; RNA, Long Noncoding/genetics ; Reperfusion Injury/genetics ; Reperfusion Injury/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
circDLPAG4/HECTD1 mediates ischaemia/reperfusion injury in endothelial cells via ER stress.
Autorzy :
Chen L; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.; Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Luo W; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Zhang W; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Chu H; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Wang J; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Dai X; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Cheng Y; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.
Zhu T; Department of Cardiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Chao J; Department of Physiology, Medical School of Southeast University, Nanjing, Jiangsu, China.; Key Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University, Nanjing, Jiangsu, China.; Department of Respiration, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu, China.
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Źródło :
RNA biology [RNA Biol] 2020 Feb; Vol. 17 (2), pp. 240-253. Date of Electronic Publication: 2019 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Endoplasmic Reticulum Stress*
Endothelial Cells/*metabolism
Reperfusion Injury/*etiology
Reperfusion Injury/*metabolism
Ubiquitin-Protein Ligases/*genetics
Animals ; Biomarkers ; Disease Models, Animal ; Disease Susceptibility ; Fluorescent Antibody Technique ; Gene Editing ; Gene Expression Profiling ; Gene Expression Regulation ; Human Umbilical Vein Endothelial Cells ; Humans ; Mice ; Myocardial Reperfusion Injury/etiology ; Myocardial Reperfusion Injury/metabolism ; Myocardial Reperfusion Injury/pathology ; RNA Interference ; Reperfusion Injury/pathology ; Transcriptome ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
Apigenin-7- O -β-d-(6″- p -coumaroyl)-glucopyranoside reduces myocardial ischaemia/reperfusion injury in an experimental model via regulating the inflammation response.
Autorzy :
Quan W; Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Air Force Medical University, Xi'an, China.; Xi'an Mental Health Center, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Ma S; Department of Pharmacy, Xijing Hospital, Air Force Medical University, Xi'an, China.
Zhu Y; Department of Pharmacy, Xijing Hospital, Air Force Medical University, Xi'an, China.
Shao Q; Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Air Force Medical University, Xi'an, China.; Xi'an Mental Health Center, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Hou J; Xi'an Mental Health Center, School of Medicine, Xi'an Jiaotong University, Xi'an, China.
Li X; Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medica of the State Administration of Traditional Chinese Medicine, Department of Pharmacology, School of Pharmacy, Air Force Medical University, Xi'an, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 80-88.
Typ publikacji :
Journal Article
MeSH Terms :
Apigenin/*pharmacology
Cardiotonic Agents/*pharmacology
Glucosides/*pharmacology
Inflammation/*drug therapy
Myocardial Reperfusion Injury/*drug therapy
Animals ; Animals, Newborn ; Apigenin/isolation & purification ; Apoptosis/drug effects ; Cardiotonic Agents/isolation & purification ; Cell Survival/drug effects ; Clematis/chemistry ; Cytokines/metabolism ; Disease Models, Animal ; Glucosides/isolation & purification ; Inflammation/pathology ; Male ; Myocardial Ischemia/drug therapy ; Myocardial Ischemia/physiopathology ; Myocardial Reperfusion Injury/physiopathology ; Myocytes, Cardiac/drug effects ; NF-kappa B/metabolism ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
XingNaoJing injection ameliorates cerebral ischaemia/reperfusion injury via SIRT1-mediated inflammatory response inhibition.
Autorzy :
Zhang YM; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Qu XY; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Tao LN; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Zhai JH; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Gao H; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Song YQ; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
Zhang SX; Department of Pharmacy, the First Hospital of Jilin University, Changchun, China.
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Źródło :
Pharmaceutical biology [Pharm Biol] 2020 Dec; Vol. 58 (1), pp. 16-24.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal/*pharmacology
Inflammation/*drug therapy
Neuroprotective Agents/*pharmacology
Reperfusion Injury/*drug therapy
Animals ; Brain/cytology ; Brain Ischemia/drug therapy ; Carbazoles/pharmacology ; Disease Models, Animal ; Drugs, Chinese Herbal/administration & dosage ; Endothelial Cells/drug effects ; Endothelial Cells/pathology ; Humans ; Infarction, Middle Cerebral Artery ; Inflammation/pathology ; Male ; Neuroprotective Agents/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/pathology ; Sirtuin 1/antagonists & inhibitors ; Sirtuin 1/metabolism
Czasopismo naukowe
Tytuł :
Anti-inflammatory and Anti-endoplasmic reticulum stress Effects of catalpol Against myocardial ischemia-reperfusion injury in streptozotocin-induced diabetic rats.
Autorzy :
Bi F; Heart Center, Zibo Central Hospital, 255400 Shandong, China.
Xu Y; Department of Echocardiography, Zibo Central Hospital, 255400 Shandong, China.
Chen G; Department of Emergency, Zibo Central Hospital, 255400 Shandong, China.
Wang P; Department of Pain Treatment, Zibo Central Hospital, 255400 Shandong, China.
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Źródło :
Anais da Academia Brasileira de Ciencias [An Acad Bras Cienc] 2020 Nov 20; Vol. 92 (4), pp. e20191148. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Diabetes Mellitus, Experimental*/drug therapy
Myocardial Reperfusion Injury*/drug therapy
Animals ; Anti-Inflammatory Agents/pharmacology ; Apoptosis ; Endoplasmic Reticulum Stress ; Iridoid Glucosides ; Male ; Oxidative Stress ; Rats ; Rats, Sprague-Dawley ; Streptozocin
Czasopismo naukowe

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