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Wyszukujesz frazę ""Reserpine"" wg kryterium: Temat


Tytuł :
An in silico approach towards identification of virulence factors in red complex pathogens targeted by reserpine.
Autorzy :
Ushanthika T; Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Smiline Girija AS; Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Paramasivam A; Biomedical Research Unit and Laboratory Animal Centre-Dental Research Cell, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
Priyadharsini JV; Biomedical Research Unit and Laboratory Animal Centre-Dental Research Cell, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, India.
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Źródło :
Natural product research [Nat Prod Res] 2021 Jun; Vol. 35 (11), pp. 1893-1898. Date of Electronic Publication: 2019 Jul 17.
Typ publikacji :
Journal Article
MeSH Terms :
Computer Simulation*
Bacteria/*pathogenicity
Reserpine/*pharmacology
Virulence Factors/*metabolism
Bacteria/drug effects ; Bacterial Proteins/metabolism ; Epitopes/chemistry ; Humans ; Microbial Sensitivity Tests ; Reserpine/chemistry ; Subcellular Fractions/metabolism ; Virulence
Czasopismo naukowe
Tytuł :
Daphnetin, a natural coumarin averts reserpine-induced fibromyalgia in mice: modulation of MAO-A.
Autorzy :
Singh L; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India.
Kaur A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India.
Singh AP; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India.
Bhatti R; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India. .
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Źródło :
Experimental brain research [Exp Brain Res] 2021 May; Vol. 239 (5), pp. 1451-1463. Date of Electronic Publication: 2021 Mar 07.
Typ publikacji :
Journal Article
MeSH Terms :
Fibromyalgia*/chemically induced
Fibromyalgia*/drug therapy
Reserpine*/toxicity
Animals ; Disease Models, Animal ; Mice ; Monoamine Oxidase ; Umbelliferones/pharmacology
Czasopismo naukowe
Tytuł :
A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
Autorzy :
Papakonstantinou E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
Vlachakis D; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.; University Research Institute of Maternal and Child Health & Precision Medicine, and UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 8 Levadias Street, 11527 Athens, Greece.; Lab of Molecular Endocrinology, Center of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation of the Academy of Athens, 11527 Athens, Greece.; Department of Informatics, Faculty of Natural and Mathematical Sciences, King's College London, Strand, London WC2R 2LS, UK.
Thireou T; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
Vlachoyiannopoulos PG; Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens, 15772 Athens, Greece.
Eliopoulos E; Laboratory of Genetics, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 75 Iera Odos, 11855 Athens, Greece.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 13; Vol. 22 (6). Date of Electronic Publication: 2021 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*chemistry
Monocarboxylic Acid Transporters/*chemistry
Muscle Proteins/*chemistry
Phloretin/*chemistry
Pyrimidinones/*chemistry
Quercetin/*chemistry
Reserpine/*analogs & derivatives
Thiophenes/*chemistry
Uracil/*analogs & derivatives
Animals ; Antineoplastic Agents/metabolism ; Binding Sites ; Biological Transport ; Drug Design ; Glycolysis/physiology ; Humans ; Lactic Acid/chemistry ; Lactic Acid/metabolism ; Molecular Docking Simulation ; Monocarboxylic Acid Transporters/antagonists & inhibitors ; Monocarboxylic Acid Transporters/genetics ; Monocarboxylic Acid Transporters/metabolism ; Muscle Proteins/antagonists & inhibitors ; Muscle Proteins/genetics ; Muscle Proteins/metabolism ; Phloretin/metabolism ; Phylogeny ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Interaction Domains and Motifs ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/chemistry ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Pyrimidinones/metabolism ; Quercetin/metabolism ; Reserpine/chemistry ; Reserpine/metabolism ; Structural Homology, Protein ; Substrate Specificity ; Thiophenes/metabolism ; Uracil/chemistry ; Uracil/metabolism
Czasopismo naukowe
Tytuł :
Reserpine inhibits DNA repair, cell proliferation, invasion and induces apoptosis in oral carcinogenesis via modulation of TGF-β signaling.
Autorzy :
Ramu AK; Department of Biochemistry and Biotechnology, Centre for Research and Development, PRIST Deemed University, Vallam, Thanjavur, Tamil Nadu, India. Electronic address: .
Ali D; Department of Zoology, College of Science King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Alarifi S; Department of Zoology, College of Science King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Syed Abuthakir MH; Biochematics Lab, Department of Bioinformatics, Bharathiar University, Coimbatore, India.
Ahmed Abdul BA; Department of Biochemistry and Biotechnology, Centre for Research and Development, PRIST Deemed University, Vallam, Thanjavur, Tamil Nadu, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jan 01; Vol. 264, pp. 118730. Date of Electronic Publication: 2020 Nov 06.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*/drug effects
Apoptosis/*drug effects
Carcinogenesis/*pathology
DNA Repair/*drug effects
Mouth Neoplasms/*pathology
Reserpine/*pharmacology
Transforming Growth Factor beta/*metabolism
9,10-Dimethyl-1,2-benzanthracene ; Animals ; Carcinogenesis/drug effects ; Cell Proliferation/drug effects ; Cricetinae ; Down-Regulation/drug effects ; Down-Regulation/genetics ; Male ; Molecular Docking Simulation ; Mouth Mucosa/drug effects ; Mouth Mucosa/pathology ; Neoplasm Invasiveness ; Neoplasm Proteins/metabolism ; Reserpine/chemistry
Czasopismo naukowe
Tytuł :
Detection of blood flow perfusion and post - occlusive reactive hyperemia in the skeletal muscle of rats.
Autorzy :
Souza-Silva E; Laboratory of Cardiovascular Biology and Department of Pharmacology, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil; Laboratory of Neurobiology of Nociception, Department of Pharmacology, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil. Electronic address: .
Ascenso R; Laboratory of Cardiovascular Biology and Department of Pharmacology, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
Tonussi CR; Laboratory of Neurobiology of Nociception, Department of Pharmacology, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil.
da Silva-Santos JE; Laboratory of Cardiovascular Biology and Department of Pharmacology, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, 88049-970 Florianópolis, Santa Catarina, Brazil. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Aug 01; Vol. 278, pp. 119571. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Hyperemia/*metabolism
Muscle, Skeletal/*metabolism
Vascular Diseases/*metabolism
Animals ; Blood Flow Velocity ; Female ; Fibromyalgia/drug therapy ; Hemodynamics ; Microcirculation ; Muscular Diseases/physiopathology ; Perfusion ; Physical Conditioning, Animal ; Rats ; Rats, Wistar ; Regional Blood Flow ; Reserpine/pharmacology ; Streptozocin ; Ultrasonography, Doppler ; Vasodilation
Czasopismo naukowe
Tytuł :
Clitorienolactones and Isoflavonoids of Clitorea ternatea Roots Alleviate Stress-Like Symptoms in a Reserpine-Induced Zebrafish Model.
Autorzy :
Ngadni MA; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Akhtar MT; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.; Institute of Industrial Biotechnology, Government College University, Lahore 54000, Pakistan.
Ismail IS; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Norazhar AI; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Lee SY; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.
Maulidiani M; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.; School of Fundamental Science, University Malaysia Terengganu (UMT), Kuala Nerus 21030, Malaysia.
Shaari K; Natural Medicines and Products Research Laboratory (NaturMeds), Institute of Bioscience, Universiti Putra Malaysia, Serdang 43400, Malaysia.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 Jul 07; Vol. 26 (14). Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Clitoria/*chemistry
Depression/*drug therapy
Flavonoids/*pharmacology
Lactones/*pharmacology
Plant Extracts/*pharmacology
Plant Roots/*chemistry
Stress, Physiological/*drug effects
Animals ; Behavior, Animal ; Depression/chemically induced ; Isoflavones/pharmacology ; Reserpine/toxicity ; Zebrafish
Czasopismo naukowe
Tytuł :
Cationic liposome-encapsulated carotenoids as a potential treatment for fibromyalgia in an animal model.
Autorzy :
Elkholy NS; Medical Biophysics Division, Physics Department, Faculty of Science, Helwan University, Cairo, Egypt.
Shafaa MW; Medical Biophysics Division, Physics Department, Faculty of Science, Helwan University, Cairo, Egypt.
Mohammed HS; Biophysics Department, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2021 Jul 01; Vol. 1867 (7), pp. 166150. Date of Electronic Publication: 2021 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Antioxidants/*pharmacology
Carotenoids/*pharmacology
Fibromyalgia/*drug therapy
Liposomes/*administration & dosage
Lutein/*chemistry
Pain/*prevention & control
Reserpine/*chemistry
Animals ; Antioxidants/chemistry ; Carotenoids/chemistry ; Female ; Fibromyalgia/etiology ; Fibromyalgia/pathology ; Liposomes/chemistry ; Pain/etiology ; Pain/pathology ; Rats
Czasopismo naukowe
Tytuł :
Regulation of intercellular biomolecule transfer-driven tumor angiogenesis and responses to anticancer therapies.
Autorzy :
Lu Z; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ortiz A; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Verginadis II; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Peck AR; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Zahedi F; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cho C; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yu P; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
DeRita RM; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Zhang H; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Kubanoff R; Department of Chemistry, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sun Y; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Yaspan AT; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Krespan E; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Beiting DP; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Radaelli E; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ryeom SW; Department of Cancer Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Diehl JA; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Rui H; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Koumenis C; Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Fuchs SY; Department of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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Źródło :
The Journal of clinical investigation [J Clin Invest] 2021 May 17; Vol. 131 (10).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Neoplasm Proteins*/antagonists & inhibitors
Neoplasm Proteins*/genetics
Neoplasm Proteins*/metabolism
Steroid Hydroxylases*/antagonists & inhibitors
Steroid Hydroxylases*/genetics
Steroid Hydroxylases*/metabolism
Neoplasms, Experimental/*drug therapy
Neovascularization, Pathologic/*drug therapy
Reserpine/*pharmacology
Sunitinib/*pharmacology
Animals ; Endothelial Cells/enzymology ; Gene Knockdown Techniques ; HCT116 Cells ; Humans ; Mice ; Mice, Knockout ; Neoplasm Metastasis ; Neoplasms, Experimental/enzymology ; Neoplasms, Experimental/genetics ; Neovascularization, Pathologic/enzymology ; Neovascularization, Pathologic/genetics
Czasopismo naukowe
Tytuł :
Effects of intravenous administration of recombinant Phα1β toxin in a mouse model of fibromyalgia.
Autorzy :
Garcia Mendes MP; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Carvalho Dos Santos D; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Rezende MJS; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Assis Ferreira LC; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Rigo FK; Graduate Program in Health Sciences, University of the Extreme South of Santa Catarina (UNESC), Criciuma, SC, Brazil.
José de Castro Junior C; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil.
Gomez MV; Nucleo de Pós-graduação, Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, MG, Brazil. Electronic address: .
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Źródło :
Toxicon : official journal of the International Society on Toxinology [Toxicon] 2021 May; Vol. 195, pp. 104-110. Date of Electronic Publication: 2021 Mar 19.
Typ publikacji :
Journal Article
MeSH Terms :
Fibromyalgia*/drug therapy
Spider Venoms/*toxicity
Administration, Intravenous ; Analgesics/therapeutic use ; Animals ; Disease Models, Animal ; Hyperalgesia/drug therapy ; Mice ; Reserpine/therapeutic use ; Spider Venoms/administration & dosage
Czasopismo naukowe
Tytuł :
Reserpine attenuates biofilm formation and virulence of Staphylococcus aureus.
Autorzy :
Parai D; Department of Microbiology, University of Kalyani, Kalyani, WB, India.
Banerjee M; Department of Microbiology, University of Kalyani, Kalyani, WB, India.
Dey P; Department of Microbiology, University of Kalyani, Kalyani, WB, India.
Mukherjee SK; Department of Microbiology, University of Kalyani, Kalyani, WB, India. Electronic address: .
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Źródło :
Microbial pathogenesis [Microb Pathog] 2020 Jan; Vol. 138, pp. 103790. Date of Electronic Publication: 2019 Oct 09.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Biofilms/*drug effects
Reserpine/*pharmacology
Staphylococcal Infections/*microbiology
Staphylococcus aureus/*drug effects
Staphylococcus aureus/*physiology
Virulence/*drug effects
Anti-Bacterial Agents/chemistry ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Chemical Phenomena ; Dose-Response Relationship, Drug ; Drug Synergism ; Hemolysis ; Microbial Sensitivity Tests ; Microbial Viability/drug effects ; Models, Molecular ; Protein Binding ; Reserpine/chemistry ; Staphylococcal Infections/drug therapy ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Inhibitors of angiotensin I converting enzyme potentiate fibromyalgia-like pain symptoms via kinin receptors in mice.
Autorzy :
Brusco I; Graduate Program in Biological Sciences: Biochemistry Toxicology, Federal University of Santa Maria, Santa Maria, RS, Brazil.
Justino AB; Graduate Program in Genetics and Biochemistry, Biotechnology Institute, Federal University of Uberlandia, Uberlandia, MG, Brazil.
Silva CR; Graduate Program in Genetics and Biochemistry, Biotechnology Institute, Federal University of Uberlandia, Uberlandia, MG, Brazil.
Scussel R; Laboratory of Cellular and Molecular Biology, Health Sciences Academic Unit, University of Extreme South Catarinense, Criciuma, SC, Brazil.
Machado-de-Ávila RA; Health Sciences Academic Unit, University of Extreme South Catarinense, Criciuma, SC, Brazil.
Oliveira SM; Graduate Program in Biological Sciences: Biochemistry Toxicology, Federal University of Santa Maria, Santa Maria, RS, Brazil. Electronic address: .
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Źródło :
European journal of pharmacology [Eur J Pharmacol] 2021 Mar 15; Vol. 895, pp. 173870. Date of Electronic Publication: 2021 Jan 18.
Typ publikacji :
Journal Article
MeSH Terms :
Angiotensin-Converting Enzyme Inhibitors/*toxicity
Fibromyalgia/*chemically induced
Nervous System/*drug effects
Nociceptive Pain/*chemically induced
Pain Threshold/*drug effects
Peptidyl-Dipeptidase A/*metabolism
Receptors, Bradykinin/*metabolism
Animals ; Behavior, Animal/drug effects ; Captopril/toxicity ; Disease Models, Animal ; Enalapril/toxicity ; Fibromyalgia/enzymology ; Fibromyalgia/physiopathology ; Male ; Mice ; Nervous System/enzymology ; Nervous System/physiopathology ; Nociceptive Pain/enzymology ; Nociceptive Pain/physiopathology ; Reserpine ; Signal Transduction
Czasopismo naukowe
Tytuł :
Involvement of Oxidative Stress and Nerve Growth Factor in Behavioral and Biochemical Deficits of Experimentally Induced Musculoskeletal Pain in Mice: Ameliorative Effects of Heraclin.
Autorzy :
Kaur A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Singh L; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Garg S; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Kaur H; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India.
Singh N; Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India.
Bhatti R; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, India. .
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Źródło :
Journal of molecular neuroscience : MN [J Mol Neurosci] 2021 Feb; Vol. 71 (2), pp. 347-357. Date of Electronic Publication: 2020 Jul 16.
Typ publikacji :
Journal Article
MeSH Terms :
Oxidative Stress*
Phytotherapy*
Analgesics/*therapeutic use
Drugs, Chinese Herbal/*therapeutic use
Furocoumarins/*therapeutic use
Musculoskeletal Pain/*drug therapy
Nerve Growth Factor/*physiology
Animals ; Anxiety/chemically induced ; Brain Chemistry/drug effects ; Cognition Disorders/chemically induced ; Cytokines/blood ; Drug Evaluation, Preclinical ; Exploratory Behavior/drug effects ; Furocoumarins/pharmacology ; Gabapentin/therapeutic use ; Hyperalgesia/chemically induced ; Hyperalgesia/drug therapy ; Hyperalgesia/physiopathology ; Mice ; Morris Water Maze Test ; Motor Activity/drug effects ; Musculoskeletal Pain/chemically induced ; Musculoskeletal Pain/physiopathology ; Neurotransmitter Agents/analysis ; Random Allocation ; Reserpine/toxicity ; Thiobarbituric Acid Reactive Substances/analysis
Czasopismo naukowe
Tytuł :
Bioactivity-Guided Isolation and Identification of New and Immunosuppressive Monoterpenoid Indole Alkaloids from Rauvolfia yunnanensis Tsiang.
Autorzy :
Li LM; School of Pharmacy, Southwest University for Nationalities, Chengdu 610041, Sichuan, China.; Research Center, Chengdu Medical College, Chengdu 610500, Sichuan, China.
Shi SD; Research Center, Chengdu Medical College, Chengdu 610500, Sichuan, China.
Liu Y; Research Center, Chengdu Medical College, Chengdu 610500, Sichuan, China.
Zou Q; Research Center, Chengdu Medical College, Chengdu 610500, Sichuan, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2019 Dec 13; Vol. 24 (24). Date of Electronic Publication: 2019 Dec 13.
Typ publikacji :
Journal Article
MeSH Terms :
Immunosuppressive Agents/*pharmacology
Rauwolfia/*chemistry
Reserpine/*pharmacology
Secologanin Tryptamine Alkaloids/*chemistry
Cell Proliferation/drug effects ; Cells, Cultured ; Humans ; Immunosuppressive Agents/chemistry ; Inhibitory Concentration 50 ; Molecular Structure ; Reserpine/chemistry ; Secologanin Tryptamine Alkaloids/pharmacology ; T-Lymphocytes/cytology ; T-Lymphocytes/drug effects
Czasopismo naukowe
Tytuł :
Oral reserpine administration in horses results in low plasma concentrations that alter platelet biology.
Autorzy :
Gilbertie JM; Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Davis JL; Department of Biomedical Sciences & Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, Virginia, USA.
Davidson GS; Clinical Pharmacy Services, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
McDonald AM; Clinical Pharmacy Services, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina, USA.
Schirmer JM; Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Schnabel LV; Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
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Źródło :
Equine veterinary journal [Equine Vet J] 2019 Jul; Vol. 51 (4), pp. 537-543. Date of Electronic Publication: 2018 Dec 14.
Typ publikacji :
Clinical Trial, Veterinary; Journal Article
MeSH Terms :
Adrenergic Uptake Inhibitors/*pharmacology
Blood Platelets/*drug effects
Horses/*blood
Reserpine/*pharmacology
Administration, Oral ; Adrenergic Uptake Inhibitors/administration & dosage ; Adrenergic Uptake Inhibitors/blood ; Adrenergic Uptake Inhibitors/pharmacokinetics ; Animals ; Area Under Curve ; Female ; Half-Life ; Male ; Reserpine/administration & dosage ; Reserpine/blood ; Reserpine/pharmacokinetics
Czasopismo naukowe
Tytuł :
Long-term pharmacological torpor of rats with feedback-controlled drug administration.
Autorzy :
Zakharova NM; Institute of Cell Biophysics, RAS, Pushchino, Moscow Region 142290, Russia.
Tarahovsky YS; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia. Electronic address: .
Komelina NP; Institute of Cell Biophysics, RAS, Pushchino, Moscow Region 142290, Russia.
Fadeeva IS; Institute of Theoretical and Experimental Biophysics, RAS, Pushchino, Moscow Region 142290, Russia.
Kovtun AL; Russian Foundation for Advanced Research, Russia.
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Źródło :
Life sciences in space research [Life Sci Space Res (Amst)] 2021 Feb; Vol. 28, pp. 18-21. Date of Electronic Publication: 2020 Nov 26.
Typ publikacji :
Journal Article
MeSH Terms :
Hypothermia/*chemically induced
Torpor/*drug effects
Animals ; Body Temperature/drug effects ; Diphenhydramine/administration & dosage ; Drug Combinations ; Drug Delivery Systems/instrumentation ; Feedback ; Heart Rate/drug effects ; Injections, Intravenous ; Ivabradine/administration & dosage ; Magnesium Sulfate/administration & dosage ; Male ; Phenothiazines/administration & dosage ; Propranolol/administration & dosage ; Propylthiouracil/administration & dosage ; Rats, Wistar ; Reserpine/administration & dosage ; Serotonin/administration & dosage ; Telemetry/veterinary
Czasopismo naukowe
Tytuł :
Antidepressant Effect of Paeoniflorin Is Through Inhibiting Pyroptosis CASP-11/GSDMD Pathway.
Autorzy :
Tian DD; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.; Department of Acupuncture-Moxibustion-Massage, Shaanxi University of Chinese Medicine, Xi'an, 712000, Shaanxi Province, People's Republic of China.
Wang M; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Liu A; Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, Shaanxi Province, People's Republic of China.
Gao MR; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.; Department of Acupuncture-Moxibustion-Massage, Shaanxi University of Chinese Medicine, Xi'an, 712000, Shaanxi Province, People's Republic of China.
Qiu C; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Yu W; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Wang WJ; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Zhang K; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Yang L; Department of Pharmacy, Tangdu Hospital, Fourth Military Medical University, Xi'an, 710038, Shaanxi Province, People's Republic of China.
Jia YY; Department of Pharmacy, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China.
Yang CB; Military Medical Innovation Center, Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China. .
Wu YM; Department of Pharmacology, School of Pharmacy, The Fourth Military Medical University, Xi'an, 710032, Shaanxi Province, People's Republic of China. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2021 Feb; Vol. 58 (2), pp. 761-776. Date of Electronic Publication: 2020 Oct 06.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*/drug effects
Antidepressive Agents/*pharmacology
Caspases, Initiator/*metabolism
Glucosides/*pharmacology
Intracellular Signaling Peptides and Proteins/*metabolism
Monoterpenes/*pharmacology
Phosphate-Binding Proteins/*metabolism
Pyroptosis/*drug effects
Adenosine Triphosphate/pharmacology ; Animals ; Antidepressive Agents/chemistry ; Antidepressive Agents/therapeutic use ; Behavior, Animal/drug effects ; CA1 Region, Hippocampal/drug effects ; Caspase Inhibitors/pharmacology ; Cell Line ; Dendritic Spines/drug effects ; Dendritic Spines/metabolism ; Depression/drug therapy ; Dipeptides/pharmacology ; Glucosides/administration & dosage ; Glucosides/chemistry ; Glucosides/therapeutic use ; Lipopolysaccharides/pharmacology ; Male ; Mice, Inbred C57BL ; Microglia/drug effects ; Microglia/metabolism ; Monoterpenes/administration & dosage ; Monoterpenes/chemistry ; Monoterpenes/therapeutic use ; Reserpine ; para-Aminobenzoates/pharmacology
Czasopismo naukowe
Tytuł :
Epoxide-derived mixed-mode chromatographic stationary phases for separation of active substances in fixed-dose combination drugs.
Autorzy :
Zhang S; School of Pharmaceutical Science & Technology, Tianjin University, Tianjin, P. R. China.
Wan QH; School of Pharmaceutical Science & Technology, Tianjin University, Tianjin, P. R. China.
Li Y; School of Pharmaceutical Science & Technology, Tianjin University, Tianjin, P. R. China.
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Źródło :
Journal of separation science [J Sep Sci] 2019 Sep; Vol. 42 (17), pp. 2796-2804. Date of Electronic Publication: 2019 Jul 02.
Typ publikacji :
Journal Article
MeSH Terms :
Epoxy Compounds/*chemistry
Methamphetamine/*analogs & derivatives
Reserpine/*isolation & purification
Capsules/chemistry ; Capsules/isolation & purification ; Chromatography, Reverse-Phase ; Methamphetamine/chemistry ; Methamphetamine/isolation & purification ; Molecular Structure ; Reserpine/chemistry ; Silicon Dioxide/chemistry ; Tablets/chemistry ; Tablets/isolation & purification
Czasopismo naukowe
Tytuł :
Anti-depressant effect of cerebrolysin in reserpine-induced depression in rats: Behavioral, biochemical, molecular and immunohistochemical evidence.
Autorzy :
El-Marasy SA; Department of Pharmacology, National Research Centre, Giza, Egypt. Electronic address: .
El Awdan SA; Department of Pharmacology, National Research Centre, Giza, Egypt.
Hassan A; Department of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
Ahmed-Farid OA; Department of Physiology, National Organization for Drug Control and Research, Giza, Egypt.
Ogaly HA; Department of Chemistry, College of Sciences, King Khalid University, Abha, Saudi Arabia; Department of Biochemistry and Chemistry of Nutrition, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt.
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Źródło :
Chemico-biological interactions [Chem Biol Interact] 2021 Jan 25; Vol. 334, pp. 109329. Date of Electronic Publication: 2020 Dec 03.
Typ publikacji :
Journal Article
MeSH Terms :
Amino Acids/*pharmacology
Antidepressive Agents/*pharmacology
Depression/*drug therapy
Reserpine/*pharmacology
Animals ; Brain-Derived Neurotrophic Factor/metabolism ; Cerebral Cortex/drug effects ; Cerebral Cortex/metabolism ; Cyclic AMP Response Element-Binding Protein/metabolism ; Depression/metabolism ; Disease Models, Animal ; Dopamine/metabolism ; Fluoxetine/pharmacology ; Hippocampus/drug effects ; Hippocampus/metabolism ; Inflammation/metabolism ; Male ; NF-kappa B/metabolism ; Neurogenesis/drug effects ; Oxidative Stress/drug effects ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Wistar ; Serotonin/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Phenoxyalkylimidazoles with an oxadiazole moiety are subject to efflux in Mycobacterium tuberculosis.
Autorzy :
Thayer MB; TB Discovery Research, Infectious Disease Research Institute, Seattle, WA, United States of America.
Parish T; TB Discovery Research, Infectious Disease Research Institute, Seattle, WA, United States of America.; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States of America.
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Źródło :
PloS one [PLoS One] 2021 Jan 22; Vol. 16 (1), pp. e0239353. Date of Electronic Publication: 2021 Jan 22 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mycobacterium tuberculosis/*drug effects
Oxadiazoles/*pharmacology
Phenols/*pharmacology
Antitubercular Agents/pharmacology ; Bacterial Proteins/drug effects ; Carbonyl Cyanide m-Chlorophenyl Hydrazone/metabolism ; Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology ; Humans ; Isoniazid/chemistry ; Isoniazid/pharmacology ; Membrane Transport Proteins/drug effects ; Microbial Sensitivity Tests/methods ; Oxadiazoles/chemistry ; Phenols/chemistry ; Reserpine/metabolism ; Reserpine/pharmacology
Czasopismo naukowe

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