Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę ""Retinal Degeneration"" wg kryterium: Temat


Tytuł:
Unveiling Drivers of Retinal Degeneration in RCS Rats: Functional, Morphological, and Molecular Insights.
Autorzy:
Ahluwalia K; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Du Z; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.
Martinez-Camarillo JC; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Naik A; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Thomas BB; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Pollalis D; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Lee SY; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; Department of Physiology & Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Dave P; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Zhou E; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Li Z; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Chester C; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Humayun MS; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Louie SG; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*
Macular Degeneration*
Retinitis Pigmentosa*
Surgeons*
Humans ; Adult ; Animals ; Rats ; Retina
Czasopismo naukowe
Tytuł:
Halofuginone prevents outer retinal degeneration in a mouse model of light-induced retinopathy.
Autorzy:
Miwa Y; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.; Aichi Animal Eye Clinic, Aichi, Japan.
Lee D; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Shoda C; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Nihon University School of Medicine, Tokyo, Japan.
Jeong H; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Negishi K; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Kurihara T; Laboratory of Photobiology, Keio University School of Medicine, Tokyo, Japan.; Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2024 Mar 27; Vol. 19 (3), pp. e0300045. Date of Electronic Publication: 2024 Mar 27 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/drug therapy
Retinal Degeneration*/etiology
Retinal Degeneration*/prevention & control
Piperidines*
Quinazolinones*
Mice ; Male ; Animals ; Disease Models, Animal ; Retina/pathology ; Electroretinography
Czasopismo naukowe
Tytuł:
Loss of 15-Lipoxygenase in Retinodegenerative RCS Rats.
Autorzy:
Mead AJ; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Ahluwalia K; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Ebright B; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Zhang Z; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Dave P; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Li Z; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Zhou E; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Naik AA; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Ngu R; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Chester C; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Lu A; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Asante I; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.; University of Southern California Ginsburg Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; University of Southern California Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Pollalis D; University of Southern California Ginsburg Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; University of Southern California Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Martinez JC; University of Southern California Ginsburg Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; University of Southern California Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Humayun M; University of Southern California Ginsburg Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; University of Southern California Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Louie S; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.; University of Southern California Ginsburg Institute for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; University of Southern California Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 15; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 15.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/pathology
Retinitis Pigmentosa*/metabolism
Surgeons*
Humans ; Rats ; Animals ; Arachidonate 15-Lipoxygenase/genetics ; Arachidonate 15-Lipoxygenase/metabolism ; Retina/metabolism ; Disease Progression ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Early inner plexiform layer thinning and retinal nerve fiber layer thickening in excitotoxic retinal injury using deep learning-assisted optical coherence tomography.
Autorzy:
Ma D; Wake Forest University School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC, 27157, USA. .; Wake Forest University Health Sciences, Winston-Salem, NC, USA. .; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA. .; School of Engineering Science, Simon Fraser University, Burnaby, BC, Canada. .
Deng W; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.; Department of Ophthalmology, SUNY Downstate Medical Center, Brooklyn, NY, USA.
Khera Z; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.
Sajitha TA; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.
Wang X; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.
Wollstein G; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.; Center for Neural Science, College of Arts and Science, New York University, New York, NY, USA.; Department of Biomedical Engineering, Tandon School of Engineering, New York University, Brooklyn, NY, USA.
Schuman JS; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.; Center for Neural Science, College of Arts and Science, New York University, New York, NY, USA.; Department of Biomedical Engineering, Tandon School of Engineering, New York University, Brooklyn, NY, USA.; Wills Eye Hospital, Philadelphia, PA, USA.; Department of Biomedical Engineering, Drexel University, Philadelphia, PA, USA.; Neuroscience Institute, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA.
Lee S; School of Engineering Science, Simon Fraser University, Burnaby, BC, Canada.; Department of Ophthalmology and Visual Sciences, The University of British Columbia, Vancouver, BC, Canada.; Mental Health and Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, UK.
Shi H; Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada.
Ju MJ; Department of Ophthalmology and Visual Sciences, The University of British Columbia, Vancouver, BC, Canada.
Matsubara J; Department of Ophthalmology and Visual Sciences, The University of British Columbia, Vancouver, BC, Canada.
Beg MF; School of Engineering Science, Simon Fraser University, Burnaby, BC, Canada.
Sarunic M; Institute of Ophthalmology, University College London, London, UK.; Department of Medical Physics and Biomedical Engineering, University College London, London, UK.
Sappington RM; Wake Forest University School of Medicine, 1 Medical Center Blvd, Winston-Salem, NC, 27157, USA.; Wake Forest University Health Sciences, Winston-Salem, NC, USA.; Translational Eye and Vision Research Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Chan KC; Department of Ophthalmology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA. .; Center for Neural Science, College of Arts and Science, New York University, New York, NY, USA. .; Department of Biomedical Engineering, Tandon School of Engineering, New York University, Brooklyn, NY, USA. .; Neuroscience Institute, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA. .; Department of Radiology, NYU Grossman School of Medicine, NYU Langone Health, New York University, New York, NY, USA. .
Pokaż więcej
Źródło:
Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Feb 01; Vol. 12 (1), pp. 19. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/chemically induced
Retinal Degeneration*/diagnostic imaging
Retinal Degeneration*/pathology
Deep Learning*
Rats ; Animals ; Tomography, Optical Coherence/methods ; N-Methylaspartate/toxicity ; Rats, Long-Evans ; Retina/pathology ; Retinal Ganglion Cells/pathology ; Nerve Fibers/pathology
Czasopismo naukowe
Tytuł:
Eye Drop with Fas-Blocking Peptide Attenuates Age-Related Macular Degeneration.
Autorzy:
Yi Y; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Pyun SH; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Kim CY; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Yun G; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Kang E; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Heo S; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Ullah I; Department of Internal Medicine, Yale University, New Haven, CT 06520, USA.
Lee SK; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Pokaż więcej
Źródło:
Cells [Cells] 2024 Mar 20; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*
Macular Degeneration*/metabolism
Humans ; Mice ; Animals ; Rabbits ; Ophthalmic Solutions/therapeutic use ; Peptides/therapeutic use ; Inflammation
Czasopismo naukowe
Tytuł:
Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration.
Autorzy:
Roy A; PamGene International B.V., 5200 BJ 's-Hertogenbosch, The Netherlands.; Division of Toxicology, Wageningen University and Research, 6708 WE Wageningen, The Netherlands.
Zhou J; Ophthalmology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22362 Lund, Sweden.
Nolet M; PamGene International B.V., 5200 BJ 's-Hertogenbosch, The Netherlands.; Department of Science & Life, Fontys University of Applied Sciences, 5612 AR Eindhoven, The Netherlands.
Welinder C; Mass Spectrometry, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22362 Lund, Sweden.
Zhu Y; Cell Death Mechanism Group, Institute for Ophthalmic Research, Eberhard-Karls-Universität Tübingen, 72072 Tübingen, Germany.
Paquet-Durand F; Cell Death Mechanism Group, Institute for Ophthalmic Research, Eberhard-Karls-Universität Tübingen, 72072 Tübingen, Germany.
Groten J; PamGene International B.V., 5200 BJ 's-Hertogenbosch, The Netherlands.
Tomar T; PamGene International B.V., 5200 BJ 's-Hertogenbosch, The Netherlands.; Lava Therapeutics N.V., 3584 CM Utrecht, The Netherlands.
Ekström P; Ophthalmology, Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22362 Lund, Sweden.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 19; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/metabolism
Animals ; Mice ; Phosphorylation ; Calmodulin/metabolism ; Protein Serine-Threonine Kinases/metabolism ; Cyclic GMP-Dependent Protein Kinases/metabolism ; Retina/metabolism ; Cyclic GMP/metabolism
Czasopismo naukowe
Tytuł:
Macrophages coordinate immune response to laser-induced injury via extracellular traps.
Autorzy:
Conedera FM; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland. .; Department of Ophthalmology, Bern University Hospital and Department of BioMedical Research, University of Bern, Bern, Switzerland. .
Kokona D; Department of Ophthalmology, Bern University Hospital and Department of BioMedical Research, University of Bern, Bern, Switzerland.
Zinkernagel MS; Department of Ophthalmology, Bern University Hospital and Department of BioMedical Research, University of Bern, Bern, Switzerland.
Stein JV; Department of Oncology, Microbiology and Immunology, University of Fribourg, Fribourg, Switzerland.
Lin CP; Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Alt C; Center for Systems Biology and Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Enzmann V; Department of Ophthalmology, Bern University Hospital and Department of BioMedical Research, University of Bern, Bern, Switzerland.
Pokaż więcej
Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 18; Vol. 21 (1), pp. 68. Date of Electronic Publication: 2024 Mar 18.
Typ publikacji:
Journal Article
MeSH Terms:
Extracellular Traps*
Retinal Degeneration*/metabolism
Animals ; Mice ; Macrophages/metabolism ; Immunity, Innate/physiology ; Inflammation/metabolism ; Mice, Knockout ; Lasers
Czasopismo naukowe
Tytuł:
Transplanted human photoreceptors transfer cytoplasmic material but not to the recipient mouse retina.
Autorzy:
Ho MT; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, 60 Leonard Ave, Toronto, ON, M5T 2S8, Canada.
Kawai K; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.; Regenerative Medicine Research and Planning Division, Rohto Pharmaceutical Co., Ltd., 6-5-4 Kunimidai, Kizugawa, Kyoto, 619-0216, Japan.
Abdo D; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Comanita L; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, 60 Leonard Ave, Toronto, ON, M5T 2S8, Canada.
Ortin-Martinez A; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, 60 Leonard Ave, Toronto, ON, M5T 2S8, Canada.
Ueno Y; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.; Regenerative Medicine Research and Planning Division, Rohto Pharmaceutical Co., Ltd., 6-5-4 Kunimidai, Kizugawa, Kyoto, 619-0216, Japan.
Tsao E; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Rastgar-Moghadam A; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, 60 Leonard Ave, Toronto, ON, M5T 2S8, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.
Xue C; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.
Cui H; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada.; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Wallace VA; Donald K. Johnson Eye Institute, Krembil Research Institute, University Health Network, 60 Leonard Ave, Toronto, ON, M5T 2S8, Canada. .; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. .; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada. .
Shoichet MS; Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada. .; Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, ON, M5S 3E2, Canada. .; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada. .; Department of Chemistry, University of Toronto, Toronto, ON, Canada. .
Pokaż więcej
Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Mar 14; Vol. 15 (1), pp. 79. Date of Electronic Publication: 2024 Mar 14.
Typ publikacji:
Journal Article
MeSH Terms:
Retina*
Retinal Degeneration*/therapy
Humans ; Animals ; Mice ; Tissue Donors ; Photoreceptor Cells, Vertebrate ; Biological Assay ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Retinal Ciliopathies and Potential Gene Therapies: A Focus on Human iPSC-Derived Organoid Models.
Autorzy:
McDonald A; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZC Leiden, The Netherlands.
Wijnholds J; Department of Ophthalmology, Leiden University Medical Center (LUMC), 2333 ZC Leiden, The Netherlands.; Netherlands Institute of Neuroscience, Royal Netherlands Academy of Arts and Sciences (KNAW), 1105 BA Amsterdam, The Netherlands.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 01; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Induced Pluripotent Stem Cells*/metabolism
Retinal Degeneration*/metabolism
Ciliopathies*/metabolism
Animals ; Humans ; Retina/metabolism ; Genetic Therapy ; Organoids/metabolism ; Eye Proteins/metabolism
Czasopismo naukowe
Tytuł:
Radiation effects on retinal layers revealed by OCT, OCT-A, and perimetry as a function of dose and time from treatment.
Autorzy:
Tamplin MR; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.; Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA.
Wang JK; Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA.; Division of Neuro-Ophthalmology, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, 52242, USA.; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA, USA.
Binkley EM; Division of Neuro-Ophthalmology, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, 52242, USA.
Garvin MK; Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA.; Department of Electrical and Computer Engineering, University of Iowa, Iowa City, IA, USA.
Hyer DE; Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Buatti JM; Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Boldt HC; Division of Neuro-Ophthalmology, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, 52242, USA.
Grumbach IM; Division of Cardiovascular Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA.; Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA.; Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA.
Kardon RH; Iowa City VA Center for the Prevention and Treatment of Visual Loss, Iowa City, IA, USA. .; Division of Neuro-Ophthalmology, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, IA, 52242, USA. .
Pokaż więcej
Źródło:
Scientific reports [Sci Rep] 2024 Feb 09; Vol. 14 (1), pp. 3380. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Neurons*/pathology
Retinal Degeneration*/pathology
Radiation Injuries*/etiology
Radiation Injuries*/pathology
Humans ; Visual Field Tests ; Tomography, Optical Coherence/methods ; Cross-Sectional Studies ; Retina/diagnostic imaging ; Retina/pathology
Czasopismo naukowe
Tytuł:
NOD1 deficiency ameliorates the progression of diabetic retinopathy by modulating bone marrow-retina crosstalk.
Autorzy:
Qiu J; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Wu J; Department of Hematology/Oncology, Chongqing University Cancer Hospital, Chongqing, China.
Chen W; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ruan Y; Division of Growth, Development and Mental Health of Children and Adolescence, Children's Hospital of Chongqing Medical University, Chongqing, China.
Mao J; Health Medical Center, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li S; Department of Laboratory Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tang X; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhao L; Center for Lipid Research, Key Laboratory of Molecular Biology for Infectious Diseases, Ministry of Education, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li S; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Li K; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Liu D; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Duan Y; Department of Endocrinology and Metabolism, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. .
Pokaż więcej
Źródło:
Stem cell research & therapy [Stem Cell Res Ther] 2024 Feb 09; Vol. 15 (1), pp. 38. Date of Electronic Publication: 2024 Feb 09.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus*/metabolism
Diabetic Retinopathy*/genetics
Diabetic Retinopathy*/therapy
Retinal Degeneration*
Nod1 Signaling Adaptor Protein*/genetics
Nod1 Signaling Adaptor Protein*/metabolism
Animals ; Mice ; Bone Marrow/metabolism ; Hematopoietic Stem Cells/metabolism ; Inflammation/genetics ; Inflammation/metabolism ; Mice, Inbred C57BL ; Retina/metabolism
Czasopismo naukowe
Tytuł:
T-type voltage-gated channels, Na -exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration.
Autorzy:
Yan J; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.
Wang L; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.
Yang QL; The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Hospital, Kunming, Yunnan, 650118, China.
Yang QX; The Third Affiliated Hospital of Kunming Medical University &Yunnan Cancer Hospital, Kunming, Yunnan, 650118, China.
He X; Graduate Training Centre of Neuroscience, University of Tübingen, Tübingen, 72076, Germany.; High-resolution Functional Imaging and Test Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.
Dong Y; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Hu Z; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Seeliger MW; Division of Ocular Neurodegeneration, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany.
Jiao K; Yunnan Eye Institute & Key Laboratory of Yunnan Province, Yunnan Eye Disease Clinical Medical Center, Affiliated Hospital of Yunnan University, Yunnan University, 176 Qingnian, Kunming, 650021, China.
Paquet-Durand F; Cell Death Mechanism Group, Institute for Ophthalmic Research, University of Tübingen, Tübingen, 72076, Germany. .
Pokaż więcej
Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Feb 01; Vol. 22 (1), pp. 92. Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Video-Audio Media; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinal Degeneration*/metabolism
Sirtuins*/metabolism
Egtazic Acid/*analogs & derivatives
Mice ; Animals ; Calpain/metabolism ; Sodium-Calcium Exchanger ; Photoreceptor Cells/metabolism ; Photoreceptor Cells/pathology ; Cell Death
Czasopismo naukowe
Tytuł:
Sustained Extracellular Electrical Stimulation Modulates the Permeability of Gap Junctions in rd1 Mouse Retina with Photoreceptor Degeneration.
Autorzy:
Stürmer S; Institute for Ophthalmic Research, University of Tuebingen, 72076 Tuebingen, Germany.
Bolz S; Institute for Ophthalmic Research, University of Tuebingen, 72076 Tuebingen, Germany.
Zrenner E; Institute for Ophthalmic Research, University of Tuebingen, 72076 Tuebingen, Germany.
Ueffing M; Institute for Ophthalmic Research, University of Tuebingen, 72076 Tuebingen, Germany.
Haq W; Institute for Ophthalmic Research, University of Tuebingen, 72076 Tuebingen, Germany.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/therapy
Retinal Degeneration*/pathology
Animals ; Mice ; Retina/pathology ; Gap Junctions ; Electric Stimulation ; Permeability
Czasopismo naukowe
Tytuł:
Hypoxic preconditioned MSCs-derived small extracellular vesicles for photoreceptor protection in retinal degeneration.
Autorzy:
Sun Y; Department of Clinical Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, Zhejiang, China.
Sun Y; Jiangsu Province Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.
Chen S; Jiangsu Province Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.
Yu Y; Jiangsu Province Key Laboratory of Medical Science and Laboratory Medicine, Department of Laboratory Medicine, School of Medicine, Jiangsu University, Zhenjiang, 212013, Jiangsu, China.
Ma Y; Department of Clinical Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, Zhejiang, China. .
Sun F; Department of Clinical Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, 321000, Zhejiang, China. .
Pokaż więcej
Źródło:
Journal of nanobiotechnology [J Nanobiotechnology] 2023 Nov 25; Vol. 21 (1), pp. 449. Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/prevention & control
Retinal Degeneration*/metabolism
Extracellular Vesicles*/metabolism
Mice ; Animals ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Retina/metabolism ; Hypoxia/metabolism
Czasopismo naukowe
Tytuł:
Choroidal Mast Cells and Pathophysiology of Age-Related Macular Degeneration.
Autorzy:
Malih S; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Medical Biotechnology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran 15614, Iran.
Song YS; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Sorenson CM; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Sheibani N; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; McPherson Eye Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.; Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705, USA.
Pokaż więcej
Źródło:
Cells [Cells] 2023 Dec 26; Vol. 13 (1). Date of Electronic Publication: 2023 Dec 26.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Macular Degeneration*
Retinal Degeneration*
Aged ; Humans ; Mast Cells ; Choroid ; Retina
Czasopismo naukowe
Tytuł:
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model.
Autorzy:
Liu Q; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Liu J; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Guo M; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Sung TC; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Wang T; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Yu T; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Tian Z; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Fan G; Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, USA.; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, 201210, Shanghai, China.
Wu W; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China.
Higuchi A; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, No. 270, Xueyuan Road, Wenzhou, 325027, Zhejiang, China. .; Department of Chemical and Materials Engineering, National Central University, No. 300, Jhongda RD., Jhongli, Taoyuan, 32001, Taiwan. .
Pokaż więcej
Źródło:
Journal of translational medicine [J Transl Med] 2023 Dec 14; Vol. 21 (1), pp. 910. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/therapy
Induced Pluripotent Stem Cells*/metabolism
Induced Pluripotent Stem Cells*/pathology
Mesenchymal Stem Cells*/metabolism
Adult ; Humans ; Rats ; Animals ; Retina/pathology ; Electroretinography ; Retinal Pigment Epithelium/pathology
Czasopismo naukowe
Tytuł:
Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration.
Autorzy:
Kretschmer V; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.
Schneider S; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.
Matthiessen PA; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.
Reichert D; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.; National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
Hotaling N; National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, Maryland, United States of America.
Glasßer G; Max Planck Institute for Polymer Research, Mainz, Germany.
Lieberwirth I; Max Planck Institute for Polymer Research, Mainz, Germany.
Bharti K; National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
De Cegli R; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.
Conte I; Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy.; University of Naples 'Federico II', Naples, Italy.
Nandrot EF; Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, France.
May-Simera HL; Faculty of Biology, Institute of Molecular Physiology, Johannes Gutenberg-University, Mainz, Germany.
Pokaż więcej
Źródło:
PLoS biology [PLoS Biol] 2023 Dec 04; Vol. 21 (12), pp. e3002402. Date of Electronic Publication: 2023 Dec 04 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/genetics
Retinal Degeneration*/pathology
Retinal Pigment Epithelium*/metabolism
Animals ; Humans ; Mice ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Cilia/genetics ; Cilia/metabolism ; Disease Models, Animal ; Epithelium ; Mice, Knockout ; Retina
Czasopismo naukowe
Tytuł:
Small Extracellular Vesicles and Oxidative Pathophysiological Mechanisms in Retinal Degenerative Diseases.
Autorzy:
Romero FJ; Hospital General de Requena, Conselleria de Sanitat, Generalitat Valenciana, 46340 Requena, Spain.
Diaz-Llopis M; Facultad de Medicina y Odontología, Universitat de València, 46010 Valencia, Spain.
Romero-Gomez MI; Facultad de Ciencias de la Salud, Universidad Europea de Valencia, 46010 Valencia, Spain.
Miranda M; Facultad de Ciencias de la Salud, Universidad CEU-Cardenal Herrera, 46115 Alfara del Patriarca, Spain.
Romero-Wenz R; Hospital General de Requena, Conselleria de Sanitat, Generalitat Valenciana, 46340 Requena, Spain.
Sancho-Pelluz J; Facultad de Medicina y Ciencias de la Salud, Universidad Católica de Valencia, 46001 Valencia, Spain.
Romero B; Facultad de Medicina y Ciencias de la Salud, Universidad Católica de Valencia, 46001 Valencia, Spain.; Unidad de Cuidados intensivos, Hospital de Manises, 46940 Manises, Spain.
Muriach M; Facultad de Ciencias de la Salud, Universitat Jaume I, 12006 Castelló de la Plana, Spain.
Barcia JM; Facultad de Medicina y Ciencias de la Salud, Universidad Católica de Valencia, 46001 Valencia, Spain.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 28; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 28.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Retinal Degeneration*/metabolism
Extracellular Vesicles*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; Retina/metabolism ; Oxidative Stress
Czasopismo naukowe
Tytuł:
Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model.
Autorzy:
Mokady D; Endogena Therapeutics, Inc., 661 University Ave, Toronto, ON M5G 0B7, Canada.
Charish J; Endogena Therapeutics, Inc., 661 University Ave, Toronto, ON M5G 0B7, Canada.
Barretto-Burns P; Endogena Therapeutics, Inc., 661 University Ave, Toronto, ON M5G 0B7, Canada.
Grisé KN; Department of Molecular Genetics, University of Toronto, Donnelly Centre Rm 1110, 160 College Street, Toronto, ON M5S 3E1, Canada.
Coles BLK; Department of Molecular Genetics, University of Toronto, Donnelly Centre Rm 1110, 160 College Street, Toronto, ON M5S 3E1, Canada.
Raab S; Endogena Therapeutics, AG, Binzmuehlestrasse 170 d, CH-8050 Zuerich, Switzerland.
Ortin-Martinez A; Endogena Therapeutics, Inc., 661 University Ave, Toronto, ON M5G 0B7, Canada.
Müller A; Endogena Therapeutics, AG, Binzmuehlestrasse 170 d, CH-8050 Zuerich, Switzerland.
Fasching B; Endogena Therapeutics, AG, Binzmuehlestrasse 170 d, CH-8050 Zuerich, Switzerland.
Jain P; Endogena Therapeutics, Inc., 661 University Ave, Toronto, ON M5G 0B7, Canada.
Drukker M; Endogena Therapeutics, AG, Binzmuehlestrasse 170 d, CH-8050 Zuerich, Switzerland.
van der Kooy D; Department of Molecular Genetics, University of Toronto, Donnelly Centre Rm 1110, 160 College Street, Toronto, ON M5S 3E1, Canada.
Steger M; Endogena Therapeutics, AG, Binzmuehlestrasse 170 d, CH-8050 Zuerich, Switzerland.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*/metabolism
Humans ; Mice ; Animals ; Methylnitrosourea ; Retina/metabolism ; Photoreceptor Cells ; Regeneration ; Disease Models, Animal ; Mammals
Czasopismo naukowe
Tytuł:
Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation-Effect of an ALG6 Modifier Variant.
Autorzy:
Monson E; Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Cideciyan AV; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Roman AJ; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sumaroka A; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Swider M; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Wu V; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Viarbitskaya I; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Jacobson SG; Center for Hereditary Retinal Degenerations, Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Fliesler SJ; Departments of Ophthalmology and Biochemistry, and Neuroscience Graduate Program, Jacobs School of Medicine and Biomedical Sciences, State University of New York-University at Buffalo, Buffalo, NY 14203, USA.; Research Service, VA Western NY Healthcare System, Buffalo, NY 14215, USA.
Pittler SJ; Department of Optometry and Vision Science, University of Alabama at Birmingham, Birmingham, AL 35294, USA.; Vision Science Research Center, School of Optometry, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Pokaż więcej
Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Jan 13; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 13.
Typ publikacji:
Journal Article
MeSH Terms:
Alkyl and Aryl Transferases*
Glucosyltransferases*/genetics
Membrane Proteins*/genetics
Retinal Degeneration*/genetics
Humans ; Genes, Modifier ; Mutation ; Retina
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies