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Wyszukujesz frazę ""Retinoblastoma Binding Proteins"" wg kryterium: Temat


Tytuł:
Integrative analysis of multi-omics data reveals inhibition of RB1 signaling promotes apatinib resistance of hepatocellular carcinoma.
Autorzy:
He K; Minimally Invasive Tumor Therapies Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.; Department of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.; Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
An S; Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Liu F; Minimally Invasive Tumor Therapies Center, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.
Chen Y; Department of Critical Care Medicine, Southern Medical University/The First School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, China.
Xiang G; Department of General Surgery, Guangdong Second Provincial General Hospital, Guangzhou 510317, China.
Wang H; Department of Biochemistry, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
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Źródło:
International journal of biological sciences [Int J Biol Sci] 2023 Aug 21; Vol. 19 (14), pp. 4511-4524. Date of Electronic Publication: 2023 Aug 21 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/drug therapy
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/drug therapy
Liver Neoplasms*/genetics
Liver Neoplasms*/pathology
Retinoblastoma Binding Proteins*
Drug Resistance, Neoplasm*
Humans ; Cell Line, Tumor ; Multiomics ; Proteomics ; Ubiquitin-Protein Ligases
Czasopismo naukowe
Tytuł:
Inhibition of high level E2F in a RB1 proficient MYCN overexpressing chicken retinoblastoma model normalizes neoplastic behaviour.
Autorzy:
Zhang H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Konjusha D; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Rafati N; National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Tararuk T; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Hallböök F; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden. .; Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala, Sweden. .
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Źródło:
Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2024 Feb; Vol. 47 (1), pp. 209-227. Date of Electronic Publication: 2023 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Retinoblastoma*/genetics
Retinoblastoma*/pathology
Retinal Neoplasms*
Chick Embryo ; Animals ; Humans ; Child ; N-Myc Proto-Oncogene Protein/genetics ; N-Myc Proto-Oncogene Protein/metabolism ; Chickens/metabolism ; Carcinogenesis ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
miR-4529-3p Promotes the Progression of Retinoblastoma by Inhibiting RB1 Expression and Activating the ERK Signaling Pathway.
Autorzy:
Gao Y; Department of Ophthalmology, Wuhan No.1 Hospital, No. 215, Zhongshan Avenue, Qiaokou District, Wuhan, 430022, Hubei, China. gggao_.
Du P; Department of Ophthalmology, Wuhan No.1 Hospital, No. 215, Zhongshan Avenue, Qiaokou District, Wuhan, 430022, Hubei, China.
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Źródło:
Molecular biotechnology [Mol Biotechnol] 2024 Jan; Vol. 66 (1), pp. 102-111. Date of Electronic Publication: 2023 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Retinoblastoma*/genetics
Retinoblastoma*/metabolism
Retinoblastoma*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Retinal Neoplasms*/genetics
Retinal Neoplasms*/metabolism
Retinal Neoplasms*/pathology
Child ; Humans ; Animals ; Mice ; MAP Kinase Signaling System/genetics ; Cell Line, Tumor ; Signal Transduction ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Movement/genetics ; Ubiquitin-Protein Ligases/metabolism ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
An atypical location of pineoblastoma RB1 subgroup without pineal or retinal tumor.
Autorzy:
Guarnizo A; Diagnostic Neuroradiology Unit, Department of Radiology, Fundación Santa Fe de Bogotá, Carrera 7 #117-15 (110111), Bogotá, Colombia. .
Maldonado F; Diagnostic Neuroradiology Unit, Department of Radiology, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881 (C 1245 AAM), Buenos Aires, Argentina.
Baroni L; Department of Neuro-oncology, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881 (C 1245 AAM), Buenos Aires, Argentina.
Fernández-Ponce N; Department of Neuro-oncology, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881 (C 1245 AAM), Buenos Aires, Argentina.
Rugilo C; Diagnostic Neuroradiology Unit, Department of Radiology, Hospital de Pediatría Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881 (C 1245 AAM), Buenos Aires, Argentina.
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Źródło:
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2024 Mar; Vol. 40 (3), pp. 961-964. Date of Electronic Publication: 2023 Nov 02.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Pinealoma*/diagnostic imaging
Pinealoma*/genetics
Brain Neoplasms*/diagnostic imaging
Brain Neoplasms*/genetics
Retinal Neoplasms*/diagnostic imaging
Retinal Neoplasms*/pathology
Pineal Gland*/diagnostic imaging
Central Nervous System Neoplasms*/pathology
Child ; Female ; Humans ; Infant ; Ubiquitin-Protein Ligases ; Retinoblastoma Binding Proteins
Czasopismo naukowe
Tytuł:
Transformation to small cell lung cancer is irrespective of EGFR and accelerated by SMAD4-mediated ASCL1 transcription independently of RB1 in non-small cell lung cancer.
Autorzy:
Ding X; Department of Central Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Shi MX; Department of Respiratory Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Liu D; Department of Radiotherapy, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Cao JX; Department of Radiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Zhang KX; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Zhang RD; Department of General Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Zhang LP; Department of Pathology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China.
Ai KX; Department of General Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. kaixing_.
Su B; Department of Central Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. su_bo_.
Zhang J; Department of Oncology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, 200092, China. .
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Źródło:
Cell communication and signaling : CCS [Cell Commun Signal] 2024 Jan 17; Vol. 22 (1), pp. 45. Date of Electronic Publication: 2024 Jan 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/pathology
Lung Neoplasms*/pathology
Small Cell Lung Carcinoma*/genetics
Small Cell Lung Carcinoma*/drug therapy
Small Cell Lung Carcinoma*/pathology
Humans ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/therapeutic use ; ErbB Receptors/genetics ; Mutation/genetics ; Protein Kinase Inhibitors/pharmacology ; Retinoblastoma Binding Proteins/genetics ; Smad4 Protein/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł:
Investigation of the methylation changes in the promoter region of RB1 gene in retinoblastoma: Unraveling the epigenetic puzzle in retinoblastoma.
Autorzy:
Erdoğan ÖŞ; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey. Electronic address: .
Ödemiş DA; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey.
Kayım ZY; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey.
Gürbüz O; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey; İstinye University, Vocational School of Health Care Services.
Tunçer ŞB; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey.
Kılıç S; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey.
Çelik B; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey.
Tuncer S; Department of Ophthalmology, Istanbul Medical Faculty, Istanbul University, Fatih, 34093 Istanbul, Turkey.
Bay SB; Department of Pediatric and Hematologic Oncology, Oncology Institute, Istanbul University, Fatih, 34093 Istanbul, Turkey.
Kebudi R; Department of Pediatric and Hematologic Oncology, Oncology Institute, Istanbul University, Fatih, 34093 Istanbul, Turkey.
Yazıcı H; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Fatih, 34093 Istanbul, Turkey; Arel University Faculty of Medicine, Department of Basic Medical Sciences / Medical Biology.
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Źródło:
Pathology, research and practice [Pathol Res Pract] 2024 Jan; Vol. 253, pp. 154939. Date of Electronic Publication: 2023 Nov 10.
Typ publikacji:
Journal Article
MeSH Terms:
Retinoblastoma*/genetics
Retinoblastoma*/pathology
Retinal Neoplasms*/genetics
Retinal Neoplasms*/pathology
Humans ; DNA Methylation/genetics ; Epigenesis, Genetic/genetics ; Promoter Regions, Genetic/genetics ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Epstein-Barr virus miR-BART2-5p and miR-BART11-5p regulate cell proliferation, apoptosis, and migration by targeting RB and p21 in gastric carcinoma.
Autorzy:
Zhao MH; Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China.
Liu W; Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China.
Zhang X; Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China.
Zhang Y; Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China.; Department of Clinical Laboratory, Zibo Central Hospital, Zibo, China.
Luo B; Department of Pathogenic Biology, School of Basic Medicine, Qingdao University, Qingdao, China.
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Źródło:
Journal of medical virology [J Med Virol] 2023 Jan; Vol. 95 (1), pp. e28338.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epstein-Barr Virus Infections*/genetics
MicroRNAs*/metabolism
Stomach Neoplasms*/metabolism
Stomach Neoplasms*/pathology
RNA, Viral*/metabolism
Cyclin-Dependent Kinase Inhibitor p21*/metabolism
Retinoblastoma Binding Proteins*/metabolism
Humans ; Apoptosis ; Carcinoma/metabolism ; Carcinoma/pathology ; Cell Proliferation ; Herpesvirus 4, Human/genetics
Czasopismo naukowe
Tytuł:
RB1 5́UTR contains an IRES related to cell cycle control and cancer progression.
Autorzy:
Ma W; Changzhou Capmus of Hohai University, Changzhou, Jiangsu Province 213022, PR China.
Ma B; Changzhou Capmus of Hohai University, Changzhou, Jiangsu Province 213022, PR China.
Ma J; Nanjing Kingsley Biotechnology Co., Ltd, Nanjing, Jiangsu Province 210000, PR China.
Zhu R; School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Road, Wuxi, Jiangsu Province 214122, PR China. Electronic address: ry_.
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Źródło:
Gene [Gene] 2023 Dec 15; Vol. 887, pp. 147724. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Retinoblastoma*/genetics
Retinal Neoplasms*/genetics
Humans ; Internal Ribosome Entry Sites/genetics ; Protein Biosynthesis/genetics ; RNA, Messenger/genetics ; 5' Untranslated Regions/genetics ; Cell Cycle Checkpoints ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics ; Retinoblastoma Binding Proteins/metabolism
Czasopismo naukowe
Tytuł:
RB1 loss in the mesenchymal component of onychomatricoma.
Autorzy:
Liu Y; Department of Dermatology, Xijing Hospital, The Fourth Military Medical University, Xian, China.
Zou D; Department of Dermatology, Xijing Hospital, The Fourth Military Medical University, Xian, China.
Huang Q; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Wang L; Department of Dermatology, Xijing Hospital, The Fourth Military Medical University, Xian, China.
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Źródło:
Journal of cutaneous pathology [J Cutan Pathol] 2023 Dec; Vol. 50 (12), pp. 1094-1098. Date of Electronic Publication: 2023 Aug 19.
Typ publikacji:
Journal Article
MeSH Terms:
Skin Neoplasms*/genetics
Nail Diseases*/genetics
Neoplasms, Fibroepithelial*
Humans ; In Situ Hybridization, Fluorescence ; Comparative Genomic Hybridization ; Ubiquitin-Protein Ligases ; Retinoblastoma Binding Proteins
Czasopismo naukowe
Tytuł:
The Use of rAAV2-RB1-Mediated Gene Therapy in Retinoblastoma.
Autorzy:
Shi H; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
He X; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Yang Z; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Liao Q; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Ruan J; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Ge S; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Chai P; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Jia R; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Fan J; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Wen X; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
Fan X; Department of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, People's Republic of China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, People's Republic of China.
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Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Dec 01; Vol. 64 (15), pp. 31.
Typ publikacji:
Journal Article
MeSH Terms:
Retinoblastoma*/genetics
Retinoblastoma*/therapy
Retinoblastoma*/pathology
Retinal Neoplasms*/genetics
Retinal Neoplasms*/therapy
Humans ; Animals ; Mice ; Dependovirus/genetics ; Genetic Therapy ; Ubiquitin-Protein Ligases/metabolism ; Retinoblastoma Binding Proteins/genetics
SCR Organism:
Adeno-associated virus-2
Czasopismo naukowe
Tytuł:
Mutant RB1 enhances therapeutic efficacy of PARPis in lung adenocarcinoma by triggering the cGAS/STING pathway.
Autorzy:
Dong Q; Department of Systems Biology, College of Bioinformatics Science and Technology, and.; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China.
Yu T; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.; Shanghai Frontiers Science Research Center for Druggability of Cardiovascular noncoding RNA, Institute for Frontier Medical Technology, Shanghai University of Engineering Science, Shanghai, China.
Chen B; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
Liu M; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
Sun X; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Cao H; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Liu K; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
Xu H; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
Wang Y; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Zhuang S; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Jin Z; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
Liang H; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, China.
Hui Y; Department of Biochemistry and Molecular Biology, Harbin Medical University, Harbin, China.
Gu Y; Department of Systems Biology, College of Bioinformatics Science and Technology, and.
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Źródło:
JCI insight [JCI Insight] 2023 Nov 08; Vol. 8 (21). Date of Electronic Publication: 2023 Nov 08.
Typ publikacji:
Journal Article
MeSH Terms:
Adenocarcinoma of Lung*/drug therapy
Adenocarcinoma of Lung*/genetics
Carcinoma, Non-Small-Cell Lung*/drug therapy
Lung Neoplasms*/drug therapy
Lung Neoplasms*/genetics
Lung Neoplasms*/pathology
Animals ; Humans ; Mice ; Nucleotidyltransferases/genetics ; Nucleotidyltransferases/metabolism ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; Retinoblastoma Binding Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł:
RB1 screening of retinoblastoma patients in Sri Lanka using targeted next generation sequencing (NGS) and gene ratio analysis copy enumeration PCR (GRACE-PCR).
Autorzy:
Kugalingam N; Department of Chemistry, Faculty of Science, University of Colombo, Colombo, Sri Lanka. .
De Silva D; Department of Physiology, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
Abeysekera H; Lady Ridgeway Hospital, Colombo, Sri Lanka.
Nanayakkara S; National Eye Hospital, Colombo, Sri Lanka.
Tirimanne S; Department of Plant Sciences, Faculty of Science, University of Colombo, Colombo, Sri Lanka.
Ranaweera D; Department of Chemistry, Faculty of Science, University of Colombo, Colombo, Sri Lanka.
Suravajhala P; Amrita School of Biotechnology, Amrita Vishwa Visyapeetham, Clappana, Kerala, India.
Chandrasekharan V; Sri Lanka Institute of Biotechnology, Pitipana, Homagama, Sri Lanka.
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Źródło:
BMC medical genomics [BMC Med Genomics] 2023 Nov 06; Vol. 16 (1), pp. 279. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinal Neoplasms*
Retinoblastoma*
Female ; Humans ; Infant ; Male ; DNA Copy Number Variations ; High-Throughput Nucleotide Sequencing ; Polymerase Chain Reaction ; Retinoblastoma Binding Proteins/genetics ; Sri Lanka ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł:
Pharmacological induction of translational readthrough of nonsense mutations in the retinoblastoma (RB1) gene.
Autorzy:
Palomar-Siles M; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Yurevych V; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Bykov VJN; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
Wiman KG; Department of Oncology-Pathology, BioClinicum, Karolinska Institutet, Stockholm, Sweden.
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Źródło:
PloS one [PLoS One] 2023 Nov 02; Vol. 18 (11), pp. e0292468. Date of Electronic Publication: 2023 Nov 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Retinoblastoma*/genetics
Retinal Neoplasms*/pathology
Humans ; Codon, Nonsense/genetics ; Retinoblastoma Protein/genetics ; Protein Biosynthesis ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Retinoblastoma patient-derived stem cells-an in vivo model to study the role of RB1 in adipogenesis.
Autorzy:
Vincent A; Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Vision Research Foundation, 41, College Road, Chennai, Tamilnadu, India.; School of Chemical and Biotechnology, SASTRA Deemed-to-Be University, Thanjavur, India.
Natarajan V; Department of Preventive Ophthalmology, Vision Research Foundation, Chennai, India.
Khetan V; Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Medical Research Foundation, Chennai, India.
Krishnakumar S; Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Vision Research Foundation, 41, College Road, Chennai, Tamilnadu, India.
Parameswaran S; Radheshyam Kanoi Stem Cell Laboratory, Kamalnayan Bajaj Institute for Research in Vision and Ophthalmology, Vision Research Foundation, 41, College Road, Chennai, Tamilnadu, India. .
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Źródło:
Histochemistry and cell biology [Histochem Cell Biol] 2022 Aug; Vol. 158 (2), pp. 181-192. Date of Electronic Publication: 2022 Apr 21.
Typ publikacji:
Journal Article
MeSH Terms:
Adipogenesis*/genetics
Retinoblastoma*/genetics
Retinoblastoma Binding Proteins*/genetics
Stem Cells*/cytology
Stem Cells*/metabolism
Ubiquitin-Protein Ligases*/genetics
Adipocytes ; Cell Differentiation ; Humans
Czasopismo naukowe
Tytuł:
miR-222-5p promotes dysfunction of human vascular smooth muscle cells by targeting RB1.
Autorzy:
Liu Y; Department of Cardiovascular Medicine, The Second Hospital of Jilin University, Jilin, China.
Jiang G; Department of Cardiovascular Medicine, Jilin Provincial People's Hospital, Jilin, China.
Lv C; Department of Second Cardiology, Dandong First Hospital, Dandong, China.
Yang C; Department of Cardiovascular Medicine, The Second Hospital of Jilin University, Jilin, China.
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Źródło:
Environmental toxicology [Environ Toxicol] 2022 Apr; Vol. 37 (4), pp. 683-694. Date of Electronic Publication: 2021 Dec 04.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/physiology
Muscle, Smooth, Vascular*/physiopathology
Retinoblastoma Binding Proteins*/genetics
Retinoblastoma Binding Proteins*/metabolism
Animals ; Cell Movement ; Cell Proliferation ; Humans ; Mice ; Signal Transduction ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł:
RB1 gene mutations and genetic spectrum in retinoblastoma cases.
Autorzy:
Akdeniz Odemis D; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Kebudi R; Istanbul University, Oncology Institute, Division of Pediatric Hematology-Oncology, Istanbul, Türkiye.
Bayramova J; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Kilic Erciyas S; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Kuru Turkcan G; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.; Halic University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, Istanbul, Türkiye.
Tuncer SB; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Sukruoglu Erdogan O; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Celik B; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Kurt Gultaslar B; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.
Buyukkapu Bay S; Istanbul University, Oncology Institute, Division of Pediatric Hematology-Oncology, Istanbul, Türkiye.
Tuncer S; Istanbul University, Istanbul Medical Faculty, Department of Ophthalmology, Istanbul, Türkiye.
Yazici H; Istanbul University, Oncology Institute, Department of Basic Oncology, Division of Cancer Genetics, Istanbul, Türkiye.; Istanbul Arel University, Istanbul Arel Medical Faculty, Department of Medical Biology and Genetics, Istanbul, Türkiye.
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Źródło:
Medicine [Medicine (Baltimore)] 2023 Sep 08; Vol. 102 (36), pp. e35068.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Neoplasms*/genetics
Retinoblastoma*/genetics
Humans ; Algorithms ; Exons ; Mutation ; Retinoblastoma Binding Proteins/genetics ; Ubiquitin-Protein Ligases/genetics
Czasopismo naukowe
Tytuł:
Complete loss of TP53 and RB1 is associated with complex genome and low immune infiltrate in pleomorphic rhabdomyosarcoma.
Autorzy:
Beird HC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Wu CC; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Nakazawa M; Department of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Ingram D; Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Daniele JR; TRACTION Platform, Division of Therapeutics Discovery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Lazcano R; Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Little L; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Davies C; Research Department of Pathology, UCL Cancer Institute, London WC1E 6DD, UK.
Daw NC; Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Wani K; Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Wang WL; Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Song X; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Gumbs C; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Zhang J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rubin B; Institute Chair, Cleveland Clinic, Cleveland, OH 44195, USA.
Conley A; Department of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Flanagan AM; Research Department of Pathology, UCL Cancer Institute, London WC1E 6DD, UK.; Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex HA7 4LP, UK.
Lazar AJ; Department of Translational and Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Futreal PA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
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Źródło:
HGG advances [HGG Adv] 2023 Jul 19; Vol. 4 (4), pp. 100224. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Rhabdomyosarcoma*/genetics
Rhabdomyosarcoma, Embryonal*/genetics
Soft Tissue Neoplasms*
Adult ; Humans ; Child ; Genomics ; Protein Processing, Post-Translational ; Tumor Suppressor Protein p53/genetics ; Ubiquitin-Protein Ligases ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Molecular and Immunophenotypic Correlates of Metastatic Epithelioid Angiomyolipoma Include Alterations of TP53, RB1, and ATRX.
Autorzy:
McCarthy MR; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Nichols PE; The Department of Urology (Nichols, Sharma, Thompson, Leibovich, Boorjian), Mayo Clinic, Rochester, Minnesota.
Sharma V; The Department of Urology (Nichols, Sharma, Thompson, Leibovich, Boorjian), Mayo Clinic, Rochester, Minnesota.
Stanton ML; The Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, Arizona (Stanton).
Reynolds JP; The Department of Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, Florida (Reynolds).
Pitel BA; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Halling KC; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Lohse CM; the Department of Quantitative Health Sciences (Lohse), Mayo Clinic, Rochester, Minnesota.
Herrera-Hernandez L; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Thompson RH; The Department of Urology (Nichols, Sharma, Thompson, Leibovich, Boorjian), Mayo Clinic, Rochester, Minnesota.
Leibovich BC; The Department of Urology (Nichols, Sharma, Thompson, Leibovich, Boorjian), Mayo Clinic, Rochester, Minnesota.
Jimenez RE; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Boorjian SA; The Department of Urology (Nichols, Sharma, Thompson, Leibovich, Boorjian), Mayo Clinic, Rochester, Minnesota.
Cheville JC; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
Gupta S; From the Department of Laboratory Medicine and Pathology (McCarthy, Pitel, Halling, Herrera-Hernandez, Jimenez, Cheville, Gupta), Mayo Clinic, Rochester, Minnesota.
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Źródło:
Archives of pathology & laboratory medicine [Arch Pathol Lab Med] 2023 Jul 01; Vol. 147 (7), pp. 817-825.
Typ publikacji:
Journal Article
MeSH Terms:
Angiomyolipoma*/genetics
Angiomyolipoma*/pathology
Kidney Neoplasms*/pathology
Humans ; Tumor Suppressor Protein p53/genetics ; Kidney/pathology ; Mutation ; X-linked Nuclear Protein/genetics ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid leukemia.
Autorzy:
Hara Y; Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.
Shiba N; Department of Pediatrics, Yokohama City University Hospital, Yokohama, Japan.
Yoshida K; Division of Cancer Evolution, National Cancer Center Research Institute, Tokyo, Japan.; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
Yamato G; Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
Kaburagi T; Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
Shiraishi Y; Division of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan.
Ohki K; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.; Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan.
Shiozawa Y; Laboratory of Molecular Analysis, Nippon Medical School, Tokyo, Japan.
Kawamura M; Department of Clinical Laboratory Medicine, Saitama Cancer Center, Saitama, Japan.
Kawasaki H; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
Sotomatsu M; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.
Takizawa T; Department of Pediatrics, Gunma University Graduate School of Medicine, Maebashi, Japan.
Matsuo H; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shimada A; Department of Pediatrics, Jichi Medical University, Shimotsuke, Japan.
Kiyokawa N; Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan.
Tomizawa D; Division of Leukemia and Lymphoma, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
Taga T; Department of Pediatrics, Shiga University of Medical Science, Otsu, Japan.
Ito E; Department of Pediatrics, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Horibe K; Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Miyano S; M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
Adachi S; Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Taki T; Department of Medical Technology, Kyorin University Faculty of Health Sciences, Mitaka, Japan.
Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.; Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan.; Department of Medicine, Centre for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden.
Hayashi Y; Department of Hematology and Oncology, Gunma Children's Medical Center, Shibukawa, Japan.; Institute of Physiology and Medicine, Jobu University, Takasaki, Japan.
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Źródło:
Genes, chromosomes & cancer [Genes Chromosomes Cancer] 2023 Jul; Vol. 62 (7), pp. 412-422. Date of Electronic Publication: 2023 Apr 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Leukemia, Myeloid, Acute*/pathology
Humans ; Child ; Mutation ; Prognosis ; Kaplan-Meier Estimate ; Tumor Suppressor Protein p53/genetics ; Glucose Transporter Type 5/genetics ; Ubiquitin-Protein Ligases/genetics ; Retinoblastoma Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
Ginsenoside Rb1 stabilized and paclitaxel / protopanaxadiol co-loaded nanoparticles for synergistic treatment of breast tumor.
Autorzy:
Lu L; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Ao H; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Fu J; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Li M; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Guo Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Guo Y; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Han M; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Shi R; China-Japan Friendship Hospital, No. 2 Yinghuayuan Dongjie, Chaoyang District, Bejing, China. Electronic address: shi_.
Wang X; Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2023 Jul; Vol. 163, pp. 114870. Date of Electronic Publication: 2023 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Ginsenosides*/pharmacology
Nanoparticles*/chemistry
Breast Neoplasms*/drug therapy
Humans ; Female ; Paclitaxel ; Cell Line, Tumor ; Tumor Microenvironment ; Ubiquitin-Protein Ligases ; Retinoblastoma Binding Proteins
Czasopismo naukowe

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