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Tytuł:
Systemic Review of Clot Retraction Modulators.
Autorzy:
Guilbeau A; LSUHSC School of Medicine, Public University, New Orleans, LA 70112, USA.
Majumder R; Department of Interdisciplinary Oncology, New Orleans, LA 70112, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jun 25; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 25.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Blood Platelets*/metabolism
Platelet Aggregation*
Clot Retraction ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Quantification and optimization of clot retraction in washed human platelets by Sonoclot coagulation analysis.
Autorzy:
Yadav P; Department of Zoology, School of Biological Sciences, Central University of Punjab, Bathinda, India.
Beura SK; Department of Zoology, School of Biological Sciences, Central University of Punjab, Bathinda, India.
Panigrahi AR; Department of Zoology, School of Biological Sciences, Central University of Punjab, Bathinda, India.
Singh SK; Department of Zoology, School of Biological Sciences, Central University of Punjab, Bathinda, India.
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Źródło:
International journal of laboratory hematology [Int J Lab Hematol] 2022 Feb; Vol. 44 (1), pp. 177-185. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets*
Clot Retraction*
Blood Coagulation Tests/*methods
Blood Coagulation Tests/*standards
Platelet Function Tests/*methods
Platelet Function Tests/*standards
Blood Coagulation ; Blood Coagulation Tests/instrumentation ; Calcium/blood ; Flow Cytometry/methods ; Flow Cytometry/standards ; Healthy Volunteers ; Hemostasis ; Humans ; Microscopy, Phase-Contrast/methods ; Microscopy, Phase-Contrast/standards ; Platelet Count ; Platelet Function Tests/instrumentation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Asymmetrical Forces Dictate the Distribution and Morphology of Platelets in Blood Clots.
Autorzy:
Kovalenko TA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., 109029 Moscow, Russia.
Giraud MN; Cardiology, Faculty of Science and Medicine, University of Fribourg, CH-1700 Fribourg, Switzerland.
Eckly A; BPPS UMR-S 1255, EFS Grand Est, FMTS, INSERM, University of Strasbourg, F-67065 Strasbourg, France.
Ribba AS; Institute for Advanced Biosciences, University Grenoble Alpes, CNRS UMR 5309, INSERM U1209, F-38700 Grenoble, France.
Proamer F; BPPS UMR-S 1255, EFS Grand Est, FMTS, INSERM, University of Strasbourg, F-67065 Strasbourg, France.
Fraboulet S; Institute for Advanced Biosciences, University Grenoble Alpes, CNRS UMR 5309, INSERM U1209, F-38700 Grenoble, France.
Podoplelova NA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., 109029 Moscow, Russia.; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology Named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia.
Valentin J; Cardiology, Faculty of Science and Medicine, University of Fribourg, CH-1700 Fribourg, Switzerland.
Panteleev MA; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., 109029 Moscow, Russia.; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology Named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia.
Gonelle-Gispert C; Surgical Research Unit, Faculty of Science and Medicine, University of Fribourg, CH-1700 Fribourg, Switzerland.
Cook S; Cardiology, Faculty of Science and Medicine, University of Fribourg, CH-1700 Fribourg, Switzerland.
Lafanechère L; Institute for Advanced Biosciences, University Grenoble Alpes, CNRS UMR 5309, INSERM U1209, F-38700 Grenoble, France.
Sveshnikova AN; Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, 30 Srednyaya Kalitnikovskaya str., 109029 Moscow, Russia.; National Medical Research Centre of Pediatric Hematology, Oncology and Immunology Named after Dmitry Rogachev, 1 Samory Mashela St, 117198 Moscow, Russia.
Sadoul K; Institute for Advanced Biosciences, University Grenoble Alpes, CNRS UMR 5309, INSERM U1209, F-38700 Grenoble, France.
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Źródło:
Cells [Cells] 2021 Mar 06; Vol. 10 (3). Date of Electronic Publication: 2021 Mar 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Coagulation*
Models, Statistical*
Blood Platelets/*chemistry
Fibrin/*chemistry
Intracranial Thrombosis/*pathology
Biomechanical Phenomena ; Blood Platelets/pathology ; Clot Retraction ; Computer Simulation ; Fibrin/ultrastructure ; Humans ; Intracranial Thrombosis/surgery ; Percutaneous Coronary Intervention/methods
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Antithrombotic Agent Pterostilbene Interferes with Integrin α IIb β 3 -Mediated Inside-Out and Outside-In Signals in Human Platelets.
Autorzy:
Huang WC; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Lin KC; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Chi Mei Medical Center, Department of Neurology, Tainan 710, Taiwan.
Hsia CW; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hsia CH; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Translational Medicine Center, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan.
Chen TY; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Bhavan PS; Department of Zoology, Bharathiar University, Coimbatore, Tamil Nadu 641046, India.
Sheu JR; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.
Hou SM; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 110, Taiwan.; Department of Cardiovascular Center, Cathay General Hospital, Taipei 106, Taiwan.; Division of Cardiovascular Surgery, Department of Surgery, School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City 242, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Mar 31; Vol. 22 (7). Date of Electronic Publication: 2021 Mar 31.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
Platelet Glycoprotein GPIIb-IIIa Complex/*drug effects
Stilbenes/*metabolism
Animals ; Blood Coagulation/drug effects ; Blood Platelets/drug effects ; Clot Retraction/drug effects ; Collagen ; Fibrinogen/metabolism ; Hemostasis/drug effects ; Humans ; Integrin alpha2/drug effects ; Integrin alpha2/metabolism ; Integrin beta3/drug effects ; Integrin beta3/metabolism ; Integrins/drug effects ; Integrins/metabolism ; Mice ; P-Selectin/metabolism ; Phosphorylation ; Platelet Activation/drug effects ; Platelet Aggregation/drug effects ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Signal Transduction/drug effects ; Stilbenes/pharmacology ; Thrombosis/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Characterization of Integrin αIIbβ3-Mediated Outside-in Signaling by Protein Kinase Cδ in Platelets.
Autorzy:
Chaudhary PK; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Kim S; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Jee Y; College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University, Jeju 63243, Korea.
Lee SH; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
Kim S; College of Veterinary Medicine, Chungbuk National University, Cheongju 28644, Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2020 Sep 08; Vol. 21 (18). Date of Electronic Publication: 2020 Sep 08.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Platelets/*metabolism
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Protein Kinase C-delta/*metabolism
Animals ; Blood Platelets/physiology ; Clot Retraction/physiology ; Female ; Fibrinogen/metabolism ; Focal Adhesion Kinase 2/metabolism ; Integrins/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Platelet Activation/physiology ; Platelet Adhesiveness/physiology ; Platelet Aggregation/physiology ; Platelet Glycoprotein GPIIb-IIIa Complex/physiology ; Protein Kinase C-delta/physiology ; Signal Transduction/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dasatinib Inhibits Procoagulant and Clot Retracting Activities of Human Platelets.
Autorzy:
Beke Debreceni I; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Kálmán Laki Doctoral School, 4032 Debrecen, Hungary. .
Mezei G; Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. .
Batár P; Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. .
Illés Á; Division of Hematology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary. .
Kappelmayer J; Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Kálmán Laki Doctoral School, 4032 Debrecen, Hungary. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2019 Oct 31; Vol. 20 (21). Date of Electronic Publication: 2019 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Blood Coagulation/*drug effects
Blood Platelets/*drug effects
Clot Retraction/*drug effects
Dasatinib/*pharmacology
Platelet Activation/*drug effects
Blood Platelets/metabolism ; Crotalid Venoms/pharmacology ; Humans ; Lectins, C-Type ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/blood ; Phosphatidylserines/metabolism ; Phosphorylation/drug effects ; Protein Kinase Inhibitors/pharmacology ; Pyrimidines/pharmacology ; Thrombin/metabolism ; src-Family Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Platycodin D inhibits platelet function and thrombus formation through inducing internalization of platelet glycoprotein receptors.
Autorzy:
Luo Q; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Wei G; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Wu X; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Tang K; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Xu M; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China.
Wu Y; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Liu Y; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Li X; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Sun Z; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.
Ju W; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China.
Qi K; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.
Chen C; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China.
Yan Z; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.
Cheng H; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.
Zhu F; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.
Li Z; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China.; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China.
Zeng L; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China.; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China.
Xu K; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China. .; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China. .; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China. .
Qiao J; Blood Diseases Institute, Xuzhou Medical University, 84 West Huaihai Road, Xuzhou, 221002, China. .; Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, 99 West Huaihai Rd, Quanshan District, Xuzhou, 221002, China. .; Key Laboratory of Bone Marrow Stem Cell, Xuzhou, Jiangsu, China. .
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Źródło:
Journal of translational medicine [J Transl Med] 2018 Nov 15; Vol. 16 (1), pp. 311. Date of Electronic Publication: 2018 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*metabolism
Blood Platelets/*pathology
Endocytosis/*drug effects
Platelet Membrane Glycoproteins/*metabolism
Saponins/*pharmacology
Thrombosis/*pathology
Triterpenes/*pharmacology
Animals ; Apoptosis/drug effects ; Arteries/drug effects ; Arteries/pathology ; Blood Platelets/drug effects ; Clot Retraction/drug effects ; Hemostasis/drug effects ; Humans ; Mice, Inbred C57BL ; P-Selectin/metabolism ; Phospholipase C gamma/metabolism ; Phosphorylation/drug effects ; Platelet Aggregation/drug effects ; Signal Transduction/drug effects ; Syk Kinase/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Interactive protein network of FXIII-A1 in lipid rafts of activated and non-activated platelets.
Autorzy:
Rabani V; a EA 3920 - Université de Franche Comté , Besançon , France.
Montange D; a EA 3920 - Université de Franche Comté , Besançon , France.; b Laboratoire de Pharmacologie Clinique et Toxicologie , CHU de Besançon , France.
Davani S; a EA 3920 - Université de Franche Comté , Besançon , France.; b Laboratoire de Pharmacologie Clinique et Toxicologie , CHU de Besançon , France.
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Źródło:
Platelets [Platelets] 2016 Sep; Vol. 27 (6), pp. 598-602. Date of Electronic Publication: 2016 Apr 11.
Typ publikacji:
Journal Article
MeSH Terms:
Platelet Activation*
Blood Platelets/*metabolism
Factor XIII/*metabolism
Membrane Microdomains/*metabolism
Protein Subunits/*metabolism
Clot Retraction ; Factor XIII/chemistry ; Humans ; Protein Binding ; Protein Interaction Mapping ; Protein Interaction Maps ; Proteome ; Proteomics/methods ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Atractylodes lactone compounds inhibit platelet activation.
Autorzy:
Chen Y; a Department of Cardiology , No. 9 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Yang W; a Department of Cardiology , No. 9 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Guo L; a Department of Cardiology , No. 9 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Wu X; b Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Zhang T; a Department of Cardiology , No. 9 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Liu J; b Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation , Shanghai Jiao Tong University School of Medicine , Shanghai , China.
Zhang J; a Department of Cardiology , No. 9 People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai , China.
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Źródło:
Platelets [Platelets] 2017 Mar; Vol. 28 (2), pp. 194-202. Date of Electronic Publication: 2016 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Atractylodes/*chemistry
Blood Platelets/*drug effects
Lactones/*pharmacology
Plant Extracts/*pharmacology
Platelet Activation/*drug effects
Platelet Aggregation Inhibitors/*pharmacology
Adenosine Triphosphate/metabolism ; Animals ; Bleeding Time ; Blood Platelets/metabolism ; Clot Retraction ; GTP Phosphohydrolases/metabolism ; GTP Phosphohydrolases/pharmacology ; Hemostasis/drug effects ; Lactones/chemistry ; Mice ; Phosphorylation ; Plant Extracts/chemistry ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/chemistry ; Proto-Oncogene Proteins c-akt/metabolism ; Thrombosis/blood ; Thrombosis/drug therapy ; p38 Mitogen-Activated Protein Kinases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CEACAM2 positively regulates integrin α IIb β 3 -mediated platelet functions.
Autorzy:
Alshahrani MM; a Thrombosis and Vascular Diseases Laboratory, School of Medical Sciences, RMIT University , Bundoora , Australia.
Kyriacou RP; a Thrombosis and Vascular Diseases Laboratory, School of Medical Sciences, RMIT University , Bundoora , Australia.
O'Malley CJ; a Thrombosis and Vascular Diseases Laboratory, School of Medical Sciences, RMIT University , Bundoora , Australia.
Heinrich G; b Department of Physiology , Center for Diabetes and Endocrine Research, University of Toledo , Toledo , OH , USA.; c Department of Pharmacology , College of Medicine and Life Sciences, University of Toledo , Toledo , OH , USA.
Najjar SM; b Department of Physiology , Center for Diabetes and Endocrine Research, University of Toledo , Toledo , OH , USA.; c Department of Pharmacology , College of Medicine and Life Sciences, University of Toledo , Toledo , OH , USA.
Jackson DE; a Thrombosis and Vascular Diseases Laboratory, School of Medical Sciences, RMIT University , Bundoora , Australia.
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Źródło:
Platelets [Platelets] 2016 Dec; Vol. 27 (8), pp. 743-750. Date of Electronic Publication: 2016 May 09.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, CD/*metabolism
Blood Platelets/*metabolism
Cell Adhesion Molecules/*metabolism
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Animals ; Antigens, CD/genetics ; Bleeding Time ; Blood Platelets/ultrastructure ; Cell Adhesion Molecules/genetics ; Clot Retraction ; Mice ; Mice, Knockout ; Platelet Adhesiveness ; Protein Binding ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cell mechanics: Contracting to stiffness.
Autorzy:
Ehrlicher A
Hartwig JH
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Źródło:
Nature materials [Nat Mater] 2011 Jan; Vol. 10 (1), pp. 12-3.
Typ publikacji:
Comment; News
MeSH Terms:
Clot Retraction*
Blood Platelets/*physiology
Biomechanical Phenomena ; Blood Coagulation/physiology ; Blood Platelets/ultrastructure ; Fibrin/physiology ; Microscopy, Atomic Force ; Stress, Mechanical
Periodyk
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mechanics and contraction dynamics of single platelets and implications for clot stiffening.
Autorzy:
Lam WA; Department of Bioengineering, University of California, Berkeley, California 94720, USA.
Chaudhuri O
Crow A
Webster KD
Li TD
Kita A
Huang J
Fletcher DA
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Źródło:
Nature materials [Nat Mater] 2011 Jan; Vol. 10 (1), pp. 61-6. Date of Electronic Publication: 2010 Dec 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Blood Coagulation*
Clot Retraction*
Blood Platelets/*physiology
Biomechanical Phenomena ; Elasticity ; Fibrin/physiology ; Fibrinogen/physiology ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
CEACAM1 regulates integrin αIIbβ3-mediated functions in platelets.
Autorzy:
Yip J; a Health Innovations Research Institute, RMIT University , Melbourne , Victoria , Australia and.
Alshahrani M; a Health Innovations Research Institute, RMIT University , Melbourne , Victoria , Australia and.
Beauchemin N; b Rosalind and Morris Goodman Cancer Research Centre, McGill University , Montreal , Quebec , Canada.
Jackson DE; a Health Innovations Research Institute, RMIT University , Melbourne , Victoria , Australia and.
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Źródło:
Platelets [Platelets] 2016; Vol. 27 (2), pp. 168-77. Date of Electronic Publication: 2015 Jul 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*metabolism
Carcinoembryonic Antigen/*blood
Fibrin/*metabolism
Fibrinogen/*metabolism
Integrin alpha2/*blood
Animals ; Bleeding Time ; Blood Coagulation ; Blood Platelets/pathology ; Calcium/blood ; Carcinoembryonic Antigen/genetics ; Clot Retraction ; Fibrin/genetics ; Fibrinogen/genetics ; Gene Expression ; Humans ; Integrin alpha2/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Signal Transduction
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of different blood components on clot retraction analysed by measuring elasticity with a free oscillating rheometer.
Autorzy:
Tynngård N; Department of Transfusion Medicine & Clinical Immunology, University Hospital, Linköping, Sweden.
Lindahl T
Ramström S
Berlin G
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Źródło:
Platelets [Platelets] 2006 Dec; Vol. 17 (8), pp. 545-54.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets*/metabolism
Clot Retraction*
Erythrocytes*/metabolism
Hemorheology*/instrumentation
Hemorheology*/methods
Elasticity/drug effects ; Erythrocyte Aggregation/drug effects ; Humans ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors/pharmacology ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Clinically relevant HOCl concentrations reduce clot retraction rate via the inhibition of energy production in platelet mitochondria.
Autorzy:
Misztal T; Department of Physical Chemistry, Medical University of Bialystok , Bialystok , Poland.
Rusak T
Tomasiak M
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Źródło:
Free radical research [Free Radic Res] 2014 Dec; Vol. 48 (12), pp. 1443-53. Date of Electronic Publication: 2014 Oct 18.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*drug effects
Clot Retraction/*drug effects
Energy Metabolism/*drug effects
Hypochlorous Acid/*pharmacology
Mitochondria/*drug effects
Animals ; Blood Platelets/cytology ; Blood Platelets/metabolism ; Dose-Response Relationship, Drug ; Mitochondria/metabolism ; Structure-Activity Relationship ; Swine ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Platelet secretion during clot retraction.
Autorzy:
White JG; Department of Laboratory Medicine and Pathology, Pediatrics, University of Minnesota Medical School, UMHC, Minneapolis 55455, USA.
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Źródło:
Platelets [Platelets] 2000 Sep; Vol. 11 (6), pp. 331-43.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Clot Retraction*
Blood Platelets/*metabolism
Blood Coagulation/drug effects ; Blood Platelets/ultrastructure ; Chelating Agents/pharmacology ; Coloring Agents ; Edetic Acid/pharmacology ; Fixatives/pharmacology ; Humans ; Hydrolyzable Tannins/pharmacology ; Polylysine/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling.
Autorzy:
Gong H; Department of Pharmacology, University of Illinois at Chicago, 835 South Wolcott Avenue, Room E403, Chicago, IL 60612, USA.
Shen B
Flevaris P
Chow C
Lam SC
Voyno-Yasenetskaya TA
Kozasa T
Du X
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Źródło:
Science (New York, N.Y.) [Science] 2010 Jan 15; Vol. 327 (5963), pp. 340-3.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Signal Transduction*
Blood Platelets/*physiology
GTP-Binding Protein alpha Subunits, G12-G13/*metabolism
Integrin beta3/*metabolism
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism
Animals ; Binding Sites ; Clot Retraction ; Fibrinogen/metabolism ; GTP-Binding Protein alpha Subunits, G12-G13/genetics ; Humans ; Ligands ; Mice ; Mice, Inbred C57BL ; Phosphorylation ; Platelet Adhesiveness ; Protein Binding ; Protein Structure, Tertiary ; Proto-Oncogene Proteins pp60(c-src)/metabolism ; RNA, Small Interfering ; Recombinant Fusion Proteins/metabolism ; rhoA GTP-Binding Protein/antagonists & inhibitors ; rhoA GTP-Binding Protein/metabolism
Czasopismo naukowe
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Tytuł:
Effects of alpha-tocopherol on platelets and the coagulation system.
Autorzy:
Bakaltcheva I; Transfusion and Homeostasis Medicine, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA. />Gyimah D
Reid T
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Źródło:
Platelets [Platelets] 2001 Nov; Vol. 12 (7), pp. 389-94.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Blood Coagulation/*drug effects
Blood Platelets/*drug effects
alpha-Tocopherol/*pharmacology
Blood Coagulation Tests ; Blood Preservation ; Clot Retraction ; Dose-Response Relationship, Drug ; Humans ; Platelet Aggregation/drug effects ; Thrombin/pharmacology
Czasopismo naukowe
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Tytuł:
EDTA-induced changes in platelet structure and function: adhesion and spreading.
Autorzy:
White JG; Department of Laboratory Medicine, University of Minnesota Medical School, Minneapolis 55455, USA.
Escolar G
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Źródło:
Platelets [Platelets] 2000 Feb; Vol. 11 (1), pp. 56-61.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blood Platelets/*cytology
Blood Platelets/*drug effects
Edetic Acid/*pharmacology
Platelet Adhesiveness/*drug effects
Anticoagulants/adverse effects ; Anticoagulants/pharmacology ; Blood Platelets/ultrastructure ; Calcium/pharmacology ; Citric Acid/pharmacology ; Clot Retraction ; Edetic Acid/adverse effects ; Glass ; Humans ; Intracellular Membranes/drug effects ; Intracellular Membranes/ultrastructure ; Magnesium/pharmacology ; Microspheres ; Platelet Glycoprotein GPIIb-IIIa Complex/metabolism ; Polyvinyls
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 30

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