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Tytuł:
Nucleoside Analog Reverse-Transcriptase Inhibitors in Membrane Environment: Molecular Dynamics Simulations.
Autorzy:
Stachowicz-Kuśnierz A; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Korchowiec B; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
Korchowiec J; Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Krakow, Poland.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2023 Aug 27; Vol. 28 (17). Date of Electronic Publication: 2023 Aug 27.
Typ publikacji:
Journal Article
MeSH Terms:
Molecular Dynamics Simulation*
Reverse Transcriptase Inhibitors*
Stavudine ; Phospholipids ; DNA-Directed RNA Polymerases
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Dolutegravir-associated resistance mutations after first-line treatment failure in Brazil.
Autorzy:
Diaz RS; Federal University of São Paulo, São Paulo, Brazil. .
Hunter JR; Federal University of São Paulo, São Paulo, Brazil.
Camargo M; Federal University of São Paulo, São Paulo, Brazil.
Dias D; Federal University of São Paulo, São Paulo, Brazil.
Galinskas J; Federal University of São Paulo, São Paulo, Brazil.
Nassar I; Federal University of São Paulo, São Paulo, Brazil.
de Lima IB; Federal University of São Paulo, São Paulo, Brazil.
Caldeira DB; Federal University of São Paulo, São Paulo, Brazil.
Sucupira MC; Federal University of São Paulo, São Paulo, Brazil.
Schechter M; Federal University of São Paulo, São Paulo, Brazil.; Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 May 24; Vol. 23 (1), pp. 347. Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article
MeSH Terms:
Reverse Transcriptase Inhibitors*/pharmacology
Reverse Transcriptase Inhibitors*/therapeutic use
HIV Infections*/drug therapy
Humans ; Brazil ; Lamivudine/pharmacology ; Lamivudine/therapeutic use ; Mutation ; Anti-Retroviral Agents ; Tenofovir ; Treatment Failure
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV protease resistance mutations in patients receiving second-line antiretroviral therapy in Libreville, Gabon.
Autorzy:
Nzengui-Nzengui, Guy Francis (AUTHOR)
Mourembou, Gaël (AUTHOR)
M'boyis-Kamdem, Hervé (AUTHOR)
Kombila-Koumavor, Ayawa Claudine (AUTHOR)
Ndjoyi-Mbiguino, Angélique (AUTHOR)
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Źródło:
BMC Infectious Diseases. 3/14/2024, Vol. 24 Issue 1, p1-7. 7p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
7,8-Dihydroxy Efavirenz Is Not as Effective in CYP46A1 Activation In Vivo as Efavirenz or Its 8,14-Dihydroxy Metabolite.
Autorzy:
Mast N; Department of Ophthalmology and Visual Science, Case Western Reserve University, Cleveland, OH 44106, USA.
Li Y; Department of Ophthalmology and Visual Science, Case Western Reserve University, Cleveland, OH 44106, USA.
Pikuleva IA; Department of Ophthalmology and Visual Science, Case Western Reserve University, Cleveland, OH 44106, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 13; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 13.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
HIV Infections*/drug therapy
Anti-HIV Agents*/therapeutic use
Female ; Male ; Mice ; Animals ; Cholesterol 24-Hydroxylase/metabolism ; Amyloid beta-Peptides ; Benzoxazines/chemistry ; Alkynes/therapeutic use ; Cyclopropanes/therapeutic use ; Reverse Transcriptase Inhibitors/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Application of Prodrugs as a Tool to Enhance the Properties of Nucleoside Reverse Transcriptase Inhibitors.
Autorzy:
Fernandes LDR; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Lopes JR; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Bonjorno AF; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Prates JLB; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Scarim CB; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Dos Santos JL; School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
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Źródło:
Viruses [Viruses] 2023 Nov 09; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 09.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Anti-HIV Agents*/therapeutic use
Prodrugs*/pharmacology
Acquired Immunodeficiency Syndrome*/drug therapy
HIV Infections*/drug therapy
Humans ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Nucleosides/therapeutic use ; HIV ; HIV Reverse Transcriptase
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High viral suppression and detection of dolutegravir-resistance associated mutations in treatment-experienced Tanzanian adults living with HIV-1 in Dar es Salaam.
Autorzy:
Bwire GM; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium. .; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania. .
Aiko BG; Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Mosha IH; Department of Behavioural Sciences, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65015, Tanzania.
Kilapilo MS; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.
Mangara A; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Dar es Salaam Urban Cohort Study, Dar es Salaam, 65013, Tanzania.
Kazonda P; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Dar es Salaam Urban Cohort Study, Dar es Salaam, 65013, Tanzania.
Swai JP; Department of Business Studies, School of Business, Mzumbe University, Dar es Salaam, 20266, Tanzania.
Swalehe O; Department of Business Studies, School of Business, Mzumbe University, Dar es Salaam, 20266, Tanzania.
Jordan MR; Tufts University School of Medicine, Boston, MA, USA.
Vercauteren J; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium.
Sando D; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Temba D; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Shao A; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Mauka W; Managament and Development for Health, Mwai Kibaki Road, Dar es Salaam, Tanzania.
Decouttere C; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Vandaele N; Faculty of Economics and Business, Access to Medicine Research Center, KU Leuven, 3000, Leuven, Belgium.
Sangeda RZ; Department of Pharmaceutical Microbiology, School of Pharmacy, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65013, Tanzania.
Killewo J; Department of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, 65015, Tanzania.
Vandamme AM; Laboratory of Clinical and Epidemiological Virology (Rega Institute), Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research Clinical and Epidemiological Virology, Institute for the Future, KU Leuven, Rega-Herestraat 49-Bus 1040, 3000, Leuven, Belgium.; Center for Global Health and Tropical Medicine, Instituto de Higiene e Medicina Tropical, Universidade Nova de Lisboa, Lisbon, Portugal.
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 22; Vol. 13 (1), pp. 20493. Date of Electronic Publication: 2023 Nov 22.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV-1*/genetics
HIV Seropositivity*/drug therapy
Humans ; Adult ; Male ; Female ; Child ; Tanzania ; Cross-Sectional Studies ; Drug Resistance, Viral/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Mutation ; Integrases/genetics ; Viral Load
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Factors associated with immunological non-response after ART initiation: a retrospective observational cohort study.
Autorzy:
Zhao, Heping (AUTHOR)
Feng, Anping (AUTHOR)
Luo, Dan (AUTHOR)
Yuan, Tanwei (AUTHOR)
Lin, Yi-Fan (AUTHOR)
Ling, Xuemei (AUTHOR)
Zhong, Huolin (AUTHOR)
Li, Junbin (AUTHOR)
Li, Linghua (AUTHOR)
Zou, Huachun (AUTHOR)
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Źródło:
BMC Infectious Diseases. 1/29/2024, Vol. 24 Issue 1, p1-9. 9p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Preswitch Regimens Influence the Rate of Weight Gain After Switch to Tenofovir Disoproxil Fumarate, Lamivudine, and Dolutegravir (TLD): Study From an East African Cohort.
Autorzy:
Bourgi, Kassem (AUTHOR)
Ofner, Susan (AUTHOR)
Musick, Beverly (AUTHOR)
Wools-Kaloustian, Kara (AUTHOR)
Humphrey, John M (AUTHOR)
Diero, Lameck (AUTHOR)
Yiannoutsos, Constantin T (AUTHOR)
Gupta, Samir K (AUTHOR)
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Źródło:
Open Forum Infectious Diseases. Dec2023, Vol. 10 Issue 12, p1-7. 7p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022.
Autorzy:
Planinić, Ana (AUTHOR)
Begovac, Josip (AUTHOR)
Rokić, Filip (AUTHOR)
Šimičić, Petra (AUTHOR)
Oroz, Maja (AUTHOR)
Jakovac, Katja (AUTHOR)
Vugrek, Oliver (AUTHOR)
Zidovec-Lepej, Snjezana (AUTHOR)
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Źródło:
Viruses (1999-4915). Dec2023, Vol. 15 Issue 12, p2408. 21p.
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HTLV-1 reverse transcriptase homology model provides structural basis for sensitivity to existing nucleoside/nucleotide reverse transcriptase inhibitors.
Autorzy:
Tardiota N; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia.
Jaberolansar N; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia.; The School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
Lackenby JA; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia.; The School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, 4072, Australia.
Chappell KJ; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia.; The School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, 4072, Australia.; Australian Infectious Disease Research Centre, The University of Queensland, St Lucia, QLD, 4072, Australia.
O'Donnell JS; The Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD, 4072, Australia. .; The School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, QLD, 4072, Australia. .
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Źródło:
Virology journal [Virol J] 2024 Jan 10; Vol. 21 (1), pp. 14. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji:
Journal Article
MeSH Terms:
Human T-lymphotropic virus 1*
Paraparesis, Tropical Spastic*
Adult ; Humans ; Nucleotides ; Reverse Transcriptase Inhibitors/pharmacology ; Molecular Docking Simulation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prevalence of acquired and transmitted HIV drug resistance in Iran: a systematic review and meta-analysis.
Autorzy:
Mirzaei H; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.
Eybpoosh S; Department of Epidemiology and Biostatistics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.
Mehrabi F; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.
Shojaei MR; Department of Microbiology and Virology, Kerman University of Medical Science, Kerman, Iran.
Mirzazadeh A; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.; Department of Epidemiology and Biostatistics, Institute for Global Health Sciences, University of California, San Francisco, USA.
Khezri M; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran.; Department of Epidemiology, New York University School of Global Public Health, New York, NY, USA.
Nasiri N; School of Health, Jiroft University of Medical Sciences, Jiroft, Iran.
Sharifi H; HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, 7616911320, Iran. .; Affiliate, Institute for Global Health Sciences, University of California San Francisco, San Francisco, CA, USA. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Jan 02; Vol. 24 (1), pp. 29. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Meta-Analysis; Systematic Review; Journal Article
MeSH Terms:
HIV-1*
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Anti-HIV Agents*/therapeutic use
Anti-HIV Agents*/pharmacology
Humans ; Iran/epidemiology ; Reverse Transcriptase Inhibitors/therapeutic use ; Prevalence ; Drug Resistance, Viral ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Impact of Protease Inhibitor-Based Highly Active Antiretroviral Therapy on Fetal Subcutaneous Fat Tissue in HIV-Pregnant Women in a Middle-Income Country.
Autorzy:
Borboa-Olivares H; Community Interventions Research Branch, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Estrada-Gutierrez G; Research Direction, Instituto Nacional de Perinatologia, Mexico City 11000, Mexico.
Martinez-Portilla RJ; Clinical Research Branch, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City 11000, Mexico.
Espino-Y-Sosa S; Clinical Research Branch, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City 11000, Mexico.
Flores-Pliego A; Department of Immunobiochemistry, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Espejel-Nuñez A; Department of Immunobiochemistry, Instituto Nacional de Perinatología, Mexico City 11000, Mexico.
Camacho-Arroyo I; Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México, Mexico City 11000, Mexico.
Solis-Paredes JM; Clinical Research Branch, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City 11000, Mexico.
Villafan-Bernal JR; Laboratory of Immunogenomics and Metabolic Diseases, Instituto Nacional de Medicina Genomica, Mexico City 14610, Mexico.
Torres-Torres J; Clinical Research Branch, Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City 11000, Mexico.
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Źródło:
Viruses [Viruses] 2023 Dec 20; Vol. 16 (1). Date of Electronic Publication: 2023 Dec 20.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/drug therapy
Adult ; Child ; Humans ; Female ; Infant, Newborn ; Pregnancy ; Adolescent ; Antiretroviral Therapy, Highly Active/adverse effects ; Protease Inhibitors/therapeutic use ; Pregnant Women ; Infectious Disease Transmission, Vertical/prevention & control ; Antiviral Agents/therapeutic use ; Reverse Transcriptase Inhibitors/therapeutic use ; Fetus ; Subcutaneous Fat
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Web Service for HIV Drug Resistance Prediction Based on Analysis of Amino Acid Substitutions in Main Drug Targets.
Autorzy:
Paremskaia AI; Department of Bioinformatics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.; Live Sciences Research Center, Moscow Institute of Physics and Technology, National Research University, Institutsky Lane 9, Dolgoprudny 141700, Russia.
Rudik AV; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Filimonov DA; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Lagunin AA; Department of Bioinformatics, Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, Moscow 117997, Russia.; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Poroikov VV; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
Tarasova OA; Laboratory of Structure-Function Based Drug Design, Institute of Biomedical Chemistry, 10 bldg. 8, Pogodinskaya Str., Moscow 119121, Russia.
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Źródło:
Viruses [Viruses] 2023 Nov 11; Vol. 15 (11). Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Humans ; Bayes Theorem ; Amino Acid Substitution ; Reproducibility of Results ; HIV Reverse Transcriptase/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Drug Resistance, Viral/genetics ; HIV Protease/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
HIV-1 Resistance to Islatravir/Tenofovir Combination Therapy in Wild-Type or NRTI-Resistant Strains of Diverse HIV-1 Subtypes.
Autorzy:
Cilento ME; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Wen X; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Reeve AB; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Ukah OB; CS Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA.
Snyder AA; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Carrillo CM; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Smith CP; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Edwards K; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Wahoski CC; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Kitzler DR; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Kodama EN; Division of Infectious Disease, International Institute of Disaster Science, Tohoku University, Sendai 980-8572, Japan.
Mitsuya H; Department of Refractory Viral Infections, National Center for Global Health & Medicine Research Institute, Tokyo 162-8655, Japan.; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Clinical Sciences, Kumamoto University Hospital, Kumamoto 860-8556, Japan.
Parniak MA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.
Tedbury PR; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Sarafianos SG; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
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Źródło:
Viruses [Viruses] 2023 Sep 25; Vol. 15 (10). Date of Electronic Publication: 2023 Sep 25.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV-1*/genetics
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
HIV Infections*/drug therapy
Humans ; Tenofovir/pharmacology ; Tenofovir/therapeutic use ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Drug Resistance, Viral/genetics ; Mutation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Insights into HIV-1 Reverse Transcriptase (RT) Inhibition and Drug Resistance from Thirty Years of Structural Studies.
Autorzy:
Singh AK; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Das K; Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.; Department of Microbiology, Immunology and Transplantation, KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
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Źródło:
Viruses [Viruses] 2022 May 11; Vol. 14 (5). Date of Electronic Publication: 2022 May 11.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Drug Resistance, Viral*
HIV Infections*
HIV-1*/drug effects
Reverse Transcriptase Inhibitors*/pharmacology
Reverse Transcriptase Inhibitors*/therapeutic use
HIV Reverse Transcriptase/genetics ; Humans
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transmitted drug resistance and subtype patterns of viruses from reported new HIV diagnoses in Germany, 2017-2020.
Autorzy:
Fiebig U; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Altmann B; Unit 18 'HIV and other Retroviruses', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Hauser A; Unit 18 'HIV and other Retroviruses', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Koppe U; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Hanke K; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany.
Gunsenheimer-Bartmeyer B; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Bremer V; Unit 34 'HIV/AIDS, STI and Blood-borne Infections', Department of Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Baumgarten A; Center for Infectiology Berlin-Prenzlauer Berg, Nordufer 20, 13353, Berlin, Germany.
Bannert N; Unit 18 'HIV and other Retroviruses, Sexually transmitted bacterial Pathogens (STI) and HIV', Department of Infectious Diseases, Robert Koch Institute, Berlin, Germany. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2023 Oct 10; Vol. 23 (1), pp. 673. Date of Electronic Publication: 2023 Oct 10.
Typ publikacji:
Journal Article
MeSH Terms:
HIV Infections*/diagnosis
HIV Infections*/drug therapy
HIV Infections*/epidemiology
Sexual and Gender Minorities*
Anti-HIV Agents*/pharmacology
Anti-HIV Agents*/therapeutic use
Viruses*
Male ; Humans ; Homosexuality, Male ; Drug Resistance, Viral/genetics ; Mutation ; DNA-Directed RNA Polymerases/genetics ; Reverse Transcriptase Inhibitors/pharmacology ; Reverse Transcriptase Inhibitors/therapeutic use ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 6392

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