Application of a small molecule inhibitor screen approach to identify CXCR4 downstream signaling pathways that promote a mesenchymal and fulvestrant-resistant phenotype in breast cancer cells.
Autorzy:
Matossian MD; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA. Elliott S; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA. RhodesLV; Department of Biology, Florida Gulf Coast University, Fort Myers, FL 33965, USA. Martin EC; Department of Biological and Agricultural Engineering Biology, Louisiana State University, Baton Rouge, LA 70803, USA. Hoang VT; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA. Burks HE; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA. Zuercher WJ; Structural Genomics Consortium, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA. Drewry DH; Structural Genomics Consortium, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA. Collins-Burow BM; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA. Burow ME; Department of Medicine, Section of Hematology and Oncology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
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Źródło:
Oncology letters [Oncol Lett] 2021 May; Vol. 21 (5), pp. 380. Date of Electronic Publication: 2021 Mar 16.
Drug resistance profiling of a new triple negative breast cancer patient-derived xenograft model.
Autorzy:
Matossian MD; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. Burks HE; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. Elliott S; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. Hoang VT; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. Bowles AC; Tulane Center for Stem Cell Research and Regenerative Medicine, New Orleans, LA, USA. Sabol RA; Tulane Center for Stem Cell Research and Regenerative Medicine, New Orleans, LA, USA. Wahba B; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. Anbalagan M; Department of Structural and Cellular Biology, Tulane University, New Orleans, LA, USA. Rowan B; Department of Structural and Cellular Biology, Tulane University, New Orleans, LA, USA. Abazeed ME; Cleveland Clinic, Department of Radiation Oncology, Cleveland, OH, USA. Bunnell BA; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA.; Tulane Center for Stem Cell Research and Regenerative Medicine, New Orleans, LA, USA. Moroz K; Department of Pathology, Tulane University School of Medicine, New Orleans, LA, USA.; Louisiana Cancer Research Center, Biospecimen Core, New Orleans, LA, USA. Miele L; Department of Genetics and Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA, USA. RhodesLV; Department of Biology, Florida Gulf Coast University, Fort Myers, FL, USA. Jones SD; Tulane Cancer Center, New Orleans, LA, USA.; Department of Surgery, Tulane University School of Medicine, New Orleans, LA, USA. Martin EC; Department of Agricultural Engineering, Louisiana State University, Baton Rouge, LA, USA. Collins-Burow BM; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA.; Tulane Cancer Center, New Orleans, LA, USA. Burow ME; Department of Medicine, Section of Hematology & Medical Oncology, Tulane University School of Medicine, New Orleans, LA, USA. .; Department of Pharmacology, Tulane University School of Medicine, New Orleans, LA, USA. .; Tulane Cancer Center, New Orleans, LA, USA. .
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Źródło:
BMC cancer [BMC Cancer] 2019 Mar 07; Vol. 19 (1), pp. 205. Date of Electronic Publication: 2019 Mar 07.
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