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Tytuł :
A real-life study on the impact of direct-acting antivirals in the treatment of chronic hepatitis C in liver transplant recipients at two university centers in Northeastern Brazil.
Autorzy :
Silva IPL; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Pós-Graduação em Medicina Tropical, Recife, Pernambuco, Brazil.
Batista AD; Universidade Federal de Pernambuco, Hospital das Clínicas, Serviço de Gastroenterologia e Hepatologia, Recife, Pernambuco, Brazil.
Lopes EP; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Pós-Graduação em Medicina Tropical, Recife, Pernambuco, Brazil.
Filgueira NA; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Departamento de Medicina Clínica, Recife, Pernambuco, Brazil.
Carvalho BT; Universidade de Pernambuco, Unidade de Transplante do Fígado, Recife, Pernambuco, Brazil.
Santos JC; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Pós-Graduação em Medicina Tropical, Recife, Pernambuco, Brazil.
Medeiros TB; Instituto Professor Fernando Figueira de Medicina Integral, Unidade de Transplante Geral, Serviço de Hepatologia, Recife, Pernambuco, Brazil.
Melo CRL; Escola de Saúde de Pernambuco, Recife, Pernambuco, Brazil.
Lima MS; Faculdade Maurício de Nassau, Recife, Pernambuco, Brazil.; Hospital Oswaldo Cruz, Serviço de Cirurgia Geral, Recife, Pernambuco, Brazil.
Lima K; Universidade Federal de Pernambuco, Hospital das Clínicas, Laboratório Clínico, Recife, Pernambuco, Brazil.; European Virus Bioinformatics Center, Jena, Germany.
Lacerda C; Universidade de Pernambuco, Unidade de Transplante do Fígado, Recife, Pernambuco, Brazil.; Universidade de Pernambuco, Departamento de Cirurgia, Recife, Pernambuco, Brazil.
Lacerda HR; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Pós-Graduação em Medicina Tropical, Recife, Pernambuco, Brazil.; Universidade Federal de Pernambuco, Centro de Ciências Médicas, Departamento de Medicina Clínica, Recife, Pernambuco, Brazil.
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Źródło :
Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 2021 Jan 29; Vol. 63, pp. e6. Date of Electronic Publication: 2021 Jan 29 (Print Publication: 2021).
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*therapeutic use
Hepacivirus/*drug effects
Hepatitis C, Chronic/*drug therapy
Liver Transplantation/*adverse effects
Ribavirin/*therapeutic use
Aged ; Antiviral Agents/adverse effects ; Brazil ; DNA, Viral/genetics ; Drug Therapy, Combination ; Female ; Genotype ; Hepacivirus/genetics ; Humans ; Liver Cirrhosis/surgery ; Male ; Middle Aged ; Ribavirin/adverse effects ; Transplant Recipients ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Safety and efficacy of antiviral combination therapy in symptomatic patients of Covid-19 infection - a randomised controlled trial (SEV-COVID Trial): A structured summary of a study protocol for a randomized controlled trial.
Autorzy :
Panda PK; General Medicine, AIIMS Rishikesh, Rishikesh, India. .
Bandyopadhyay A; Department of Pharmacology, AIIMS Rishikesh, Rishikesh, India.
Singh BC; Department of Medicine, AIIMS Rishikesh, Rishikesh, India.
Moirangthem B; Department of Medicine, AIIMS Rishikesh, Rishikesh, India.
Chikara G; Department of Pharmacology, AIIMS Rishikesh, Rishikesh, India.
Saha S; Biochemistry, AIIMS Rishikesh, Rishikesh, India.
Bahurupi YA; Community and Family Medicine, AIIMS Rishikesh, Rishikesh, India.
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Źródło :
Trials [Trials] 2020 Oct 20; Vol. 21 (1), pp. 866. Date of Electronic Publication: 2020 Oct 20.
Typ publikacji :
Comparative Study; Letter; Randomized Controlled Trial
MeSH Terms :
Antiviral Agents/*therapeutic use
Betacoronavirus/*drug effects
Coronavirus Infections/*drug therapy
Pneumonia, Viral/*drug therapy
Ribavirin/*therapeutic use
Administration, Oral ; Adult ; Antimalarials/administration & dosage ; Antimalarials/therapeutic use ; Antiviral Agents/administration & dosage ; Betacoronavirus/genetics ; COVID-19 ; Clinical Protocols ; Combined Modality Therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Cytochrome P-450 CYP3A Inhibitors/administration & dosage ; Cytochrome P-450 CYP3A Inhibitors/therapeutic use ; Female ; Humans ; Hydroxychloroquine/administration & dosage ; Hydroxychloroquine/therapeutic use ; India/epidemiology ; Informed Consent ; Lopinavir/administration & dosage ; Lopinavir/therapeutic use ; Male ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Ribavirin/administration & dosage ; Ritonavir/administration & dosage ; Ritonavir/therapeutic use ; SARS-CoV-2 ; Safety ; Time Factors ; Treatment Outcome
Raport
Tytuł :
Sofosbuvir plus ribavirin and sofosbuvir plus ledipasvir in patients with genotype 1 or 3 hepatitis C virus and severe renal impairment: a multicentre, phase 2b, non-randomised, open-label study.
Autorzy :
Lawitz E; Texas Liver Institute, University of Texas Health San Antonio, San Antonio, TX, USA.
Landis CS; Department of Medicine, University of Washington, Seattle, WA, USA.
Flamm SL; Northwestern University, Chicago, IL, USA.
Bonacini M; Mission Gastroenterology and Hepatology, University of California, San Francisco, CA, USA.
Ortiz-Lasanta G; Fundación de Investigación, San Juan, Puerto Rico.
Huang J; University of Rochester, Rochester, NY, USA.
Zhang J; Gilead Sciences, Foster City, CA, USA.
Kirby BJ; Gilead Sciences, Foster City, CA, USA.
De-Oertel S; Gilead Sciences, Foster City, CA, USA.
Hyland RH; Gilead Sciences, Foster City, CA, USA.
Osinusi AO; Gilead Sciences, Foster City, CA, USA.
Brainard DM; Gilead Sciences, Foster City, CA, USA.
Robson R; Christchurch Clinical Studies Trust, Christchurch, New Zealand.
Maliakkal BJ; University of Rochester, Rochester, NY, USA.
Gordon SC; Henry Ford Health System, Detroit, MI, USA.
Gane EJ; Auckland Clinical Studies, Auckland, New Zealand. Electronic address: .
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Źródło :
The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2020 Oct; Vol. 5 (10), pp. 918-926. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*therapeutic use
Benzimidazoles/*therapeutic use
Fluorenes/*therapeutic use
Hepatitis C/*drug therapy
Non-Randomized Controlled Trials as Topic/*methods
Renal Insufficiency, Chronic/*complications
Ribavirin/*therapeutic use
Sofosbuvir/*therapeutic use
Uridine Monophosphate/*analogs & derivatives
Adult ; Aged ; Antiviral Agents/administration & dosage ; Antiviral Agents/adverse effects ; Antiviral Agents/pharmacokinetics ; Benzimidazoles/administration & dosage ; Benzimidazoles/adverse effects ; Benzimidazoles/pharmacokinetics ; Drug Therapy, Combination/methods ; Female ; Fluorenes/administration & dosage ; Fluorenes/adverse effects ; Fluorenes/pharmacokinetics ; Genotype ; Hepacivirus/drug effects ; Hepacivirus/genetics ; Hepatitis C/complications ; Humans ; Male ; Middle Aged ; New Zealand/epidemiology ; Renal Insufficiency, Chronic/classification ; Renal Insufficiency, Chronic/physiopathology ; Ribavirin/administration & dosage ; Ribavirin/adverse effects ; Ribavirin/pharmacokinetics ; Safety ; Sofosbuvir/administration & dosage ; Sofosbuvir/adverse effects ; Sofosbuvir/pharmacokinetics ; Treatment Outcome ; United States/epidemiology ; Uridine Monophosphate/administration & dosage ; Uridine Monophosphate/adverse effects ; Uridine Monophosphate/pharmacokinetics ; Uridine Monophosphate/therapeutic use ; Viral Load/drug effects
Czasopismo naukowe
Tytuł :
Role of Ribavirin in the Era of Direct-Acting Antiviral Therapies of Chronic Hepatitis C.
Autorzy :
Alhaddad O; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Wahb A; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Sabry A; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Khalil F; Department of Microbiology and Immunology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Elsabaawy D; Department of Clinical Pharmacy, Pharmacy College, Menoufia University , Shebin El-kom, Egypt.
Elshazly H; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Shebl N
Rady M; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
Elsabaawy M; Department of Hepatology, National Liver Institute, Menoufia University , Shebin El-kom, Egypt.
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Źródło :
Expert review of anti-infective therapy [Expert Rev Anti Infect Ther] 2020 Aug; Vol. 18 (8), pp. 817-822. Date of Electronic Publication: 2020 May 13.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*administration & dosage
Hepatitis C, Chronic/*drug therapy
Liver Cirrhosis/*drug therapy
Ribavirin/*administration & dosage
Adult ; Aged ; Antiviral Agents/adverse effects ; Cohort Studies ; Drug Therapy, Combination ; Egypt ; Female ; Humans ; Liver Cirrhosis/virology ; Liver Transplantation ; Male ; Middle Aged ; Retrospective Studies ; Ribavirin/adverse effects
Czasopismo naukowe
Tytuł :
Assessment of the Potential Adverse Events Related to Ribavirin-Interferon Combination for Novel Coronavirus Therapy.
Autorzy :
Shan W; Department of Clinical Pharmacy, The First Affiliated Hospital of Zhejiang University, 310003, China.
Hong D; Department of Clinical Pharmacy, The First Affiliated Hospital of Zhejiang University, 310003, China.
Zhu J; Zhejiang University of Technology, 310003, China.
Zhao Q; Department of Clinical Pharmacy, The First Affiliated Hospital of Zhejiang University, 310003, China.; Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, 310003, China.
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Źródło :
Computational and mathematical methods in medicine [Comput Math Methods Med] 2020 Sep 24; Vol. 2020, pp. 1391583. Date of Electronic Publication: 2020 Sep 24 (Print Publication: 2020).
Typ publikacji :
Journal Article
MeSH Terms :
Coronavirus Infections/*drug therapy
Interferons/*adverse effects
Pneumonia, Viral/*drug therapy
Ribavirin/*adverse effects
Adolescent ; Adult ; Adverse Drug Reaction Reporting Systems ; Aged ; Algorithms ; Bayes Theorem ; COVID-19 ; Data Mining ; Drug Administration Schedule ; Drug Therapy, Combination/adverse effects ; Female ; Humans ; Interferons/administration & dosage ; Male ; Middle Aged ; Neural Networks, Computer ; Odds Ratio ; Pandemics ; Patient Safety ; Ribavirin/administration & dosage ; Young Adult
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Efficacy and safety of direct acting antiviral regimens for hepatitis C virus and human immunodeficiency virus co-infection: systematic review and network meta-analysis.
Autorzy :
Zheng YX; Department of Infectious Diseases, Key Laboratory of Viral Hepatitis of Hunan, Xiangya Hospital, Central South University, Changsha, China.
Ma SJ; Department of Epidemiology and Health Statistics, School of Public Health, Central South University, Changsha, China.
Xiong YH; Department of Infectious Diseases, Key Laboratory of Viral Hepatitis of Hunan, Xiangya Hospital, Central South University, Changsha, China.
Fan XG; Department of Infectious Diseases, Key Laboratory of Viral Hepatitis of Hunan, Xiangya Hospital, Central South University, Changsha, China.
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Źródło :
Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2020 Sep; Vol. 35 (9), pp. 1477-1487. Date of Electronic Publication: 2020 Apr 15.
Typ publikacji :
Journal Article; Meta-Analysis; Systematic Review
MeSH Terms :
Antiviral Agents/*administration & dosage
Benzofurans/*administration & dosage
Coinfection/*drug therapy
HIV Infections/*diagnostic imaging
Hepatitis C, Chronic/*drug therapy
Imidazoles/*administration & dosage
Quinoxalines/*administration & dosage
Ribavirin/*administration & dosage
Administration, Oral ; Adult ; Aged ; Amides ; Antiviral Agents/adverse effects ; Benzofurans/adverse effects ; Carbamates ; Cyclopropanes ; Drug Therapy, Combination ; Female ; HIV Infections/virology ; Hepatitis C, Chronic/virology ; Humans ; Imidazoles/adverse effects ; Male ; Middle Aged ; Quinoxalines/adverse effects ; Ribavirin/adverse effects ; Safety ; Sulfonamides ; Sustained Virologic Response ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19.
Autorzy :
Elfiky AA; Biophysics Department, Faculty of Sciences, Cairo University, Giza, Egypt; College of Applied Medical Sciences, University of Al-Jouf, Saudi Arabia. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2020 May 01; Vol. 248, pp. 117477. Date of Electronic Publication: 2020 Feb 28.
Typ publikacji :
Journal Article
MeSH Terms :
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Antiviral Agents/*chemistry
Betacoronavirus/*enzymology
Coronavirus Infections/*drug therapy
Guanosine Monophosphate/*analogs & derivatives
Pneumonia, Viral/*drug therapy
RNA-Dependent RNA Polymerase/*antagonists & inhibitors
Ribavirin/*chemistry
Sofosbuvir/*chemistry
Viral Proteins/*antagonists & inhibitors
Adenosine Monophosphate/chemistry ; Adenosine Monophosphate/metabolism ; Alanine/chemistry ; Alanine/metabolism ; Alphacoronavirus/enzymology ; Alphacoronavirus/genetics ; Amino Acid Sequence ; Antiviral Agents/metabolism ; Betacoronavirus/genetics ; COVID-19 ; Catalytic Domain ; Computational Biology/methods ; Coronavirus Infections/virology ; Drug Repositioning/methods ; Guanosine Monophosphate/chemistry ; Guanosine Monophosphate/metabolism ; Guanosine Triphosphate/chemistry ; Guanosine Triphosphate/metabolism ; Humans ; Molecular Docking Simulation ; Pneumonia, Viral/virology ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; RNA-Dependent RNA Polymerase/chemistry ; RNA-Dependent RNA Polymerase/metabolism ; Ribavirin/metabolism ; SARS-CoV-2 ; Sequence Alignment ; Sequence Homology, Amino Acid ; Sofosbuvir/metabolism ; Thermodynamics ; Uridine Triphosphate/chemistry ; Uridine Triphosphate/metabolism ; Viral Proteins/chemistry ; Viral Proteins/metabolism
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
A Novel Inhaled Dry-Powder Formulation of Ribavirin Allows for Efficient Lung Delivery in Healthy Participants and Those with Chronic Obstructive Pulmonary Disease in a Phase 1 Study.
Autorzy :
Dumont EF; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Oliver AJ; GlaxoSmithKline, Middlesex, United Kingdom.
Ioannou C; GlaxoSmithKline, Middlesex, United Kingdom.
Billiard J; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Dennison J; Hammersmith Medicines Research Ltd., London, United Kingdom.
van den Berg F; Hammersmith Medicines Research Ltd., London, United Kingdom.
Yang S; GlaxoSmithKline, Middlesex, United Kingdom.
Chandrasekaran V; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Young GC; GlaxoSmithKline, Ware, United Kingdom.
Lahiry A; GlaxoSmithKline, Bangalore, India.
Starbuck DC; GlaxoSmithKline, Ware, United Kingdom.
Harrell AW; GlaxoSmithKline, Ware, United Kingdom.
Georgiou A; GlaxoSmithKline, Ware, United Kingdom.
Hopchet N; Hammersmith Medicines Research Ltd., London, United Kingdom.
Gillies A; Gillies Associates Limited, Harrogate, United Kingdom.
Baker SJ; GlaxoSmithKline, Collegeville, Pennsylvania, USA .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2020 Apr 21; Vol. 64 (5). Date of Electronic Publication: 2020 Apr 21 (Print Publication: 2020).
Typ publikacji :
Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
MeSH Terms :
Dry Powder Inhalers*/adverse effects
Antiviral Agents/*administration & dosage
Lung/*metabolism
Pulmonary Disease, Chronic Obstructive/*metabolism
Ribavirin/*administration & dosage
Administration, Inhalation ; Adult ; Aged ; Antiviral Agents/pharmacokinetics ; Antiviral Agents/therapeutic use ; Double-Blind Method ; Drug Delivery Systems ; Female ; Healthy Volunteers ; Humans ; Male ; Middle Aged ; Pulmonary Disease, Chronic Obstructive/drug therapy ; Pulmonary Disease, Chronic Obstructive/virology ; Respiratory Mucosa/metabolism ; Ribavirin/pharmacokinetics ; Ribavirin/therapeutic use ; Young Adult
Czasopismo naukowe
Tytuł :
Synthesis and antitumor activities investigation of a C-nucleoside analogue of ribavirin.
Autorzy :
Sabat N; Laboratoire de Chimie Biologique, University of Cergy-Pontoise, 5 mail Gay-Lussac, 95031, Cergy-Pontoise, France.
Migianu-Griffoni E; Université; Paris 13, Sorbonne Paris Cité, Laboratoire de Chimie, Structure, Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT), CNRS UMR 7244, 74, rue Marcel, Cachin, F-93017, Bobigny, France.
Tudela T; Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellules, ERRMECe (EA1391), Institut des Matériaux, I-MAT (FD4122), University of Cergy-Pontoise, MIR, rue Descartes, 95031, Neuville sur Oise Cedex, France.
Lecouvey M; Université; Paris 13, Sorbonne Paris Cité, Laboratoire de Chimie, Structure, Propriétés de Biomatériaux et d'Agents Thérapeutiques (CSPBAT), CNRS UMR 7244, 74, rue Marcel, Cachin, F-93017, Bobigny, France.
Kellouche S; Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellules, ERRMECe (EA1391), Institut des Matériaux, I-MAT (FD4122), University of Cergy-Pontoise, MIR, rue Descartes, 95031, Neuville sur Oise Cedex, France.
Carreiras F; Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellules, ERRMECe (EA1391), Institut des Matériaux, I-MAT (FD4122), University of Cergy-Pontoise, MIR, rue Descartes, 95031, Neuville sur Oise Cedex, France.
Gallier F; Laboratoire de Chimie Biologique, University of Cergy-Pontoise, 5 mail Gay-Lussac, 95031, Cergy-Pontoise, France.
Uziel J; Laboratoire de Chimie Biologique, University of Cergy-Pontoise, 5 mail Gay-Lussac, 95031, Cergy-Pontoise, France.
Lubin-Germain N; Laboratoire de Chimie Biologique, University of Cergy-Pontoise, 5 mail Gay-Lussac, 95031, Cergy-Pontoise, France. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2020 Feb 15; Vol. 188, pp. 112009. Date of Electronic Publication: 2019 Dec 23.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Ribavirin/*analogs & derivatives
Ribavirin/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/toxicity ; Cell Line, Transformed ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans ; Male ; Mice ; Ribavirin/toxicity
Czasopismo naukowe
Tytuł :
Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19.
Autorzy :
Yip TC; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Lui GC; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Stanley Ho Centre for Emerging Infectious Diseases, Jockey Club School of Public Health & Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Wong VW; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Chow VC; Department of Microbiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Ho TH; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Li TC; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Tse YK; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Hui DS; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Stanley Ho Centre for Emerging Infectious Diseases, Jockey Club School of Public Health & Primary Care, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Chan HL; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, Hong Kong.
Wong GL; Department of Medicine and Therapeutics, Medical Data Analytic Centre (MDAC), Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, Hong Kong .
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Źródło :
Gut [Gut] 2021 Apr; Vol. 70 (4), pp. 733-742. Date of Electronic Publication: 2020 Jul 08.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents*/administration & dosage
Antiviral Agents*/adverse effects
COVID-19*/blood
COVID-19*/complications
COVID-19*/diagnosis
COVID-19*/drug therapy
Liver*/drug effects
Liver*/virology
Alanine Transaminase/*blood
Aspartate Aminotransferases/*blood
Adrenal Cortex Hormones/administration & dosage ; Adrenal Cortex Hormones/adverse effects ; Adult ; Drug Combinations ; Female ; Hong Kong/epidemiology ; Hospitalization/statistics & numerical data ; Humans ; Liver Function Tests/methods ; Liver Function Tests/statistics & numerical data ; Lopinavir/administration & dosage ; Lopinavir/adverse effects ; Male ; Retrospective Studies ; Ribavirin/administration & dosage ; Ribavirin/adverse effects ; Ritonavir/administration & dosage ; Ritonavir/adverse effects ; SARS-CoV-2/isolation & purification ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Ropeginterferon Alfa-2b administered every two weeks for patients with genotype 2 chronic hepatitis C.
Autorzy :
Hsu SJ; Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan; Hepatology Medical Center, National Taiwan University Hospital Yunlin Branch, Yunlin, Taiwan. Electronic address: .
Yu ML; Hepatobiliary Division, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
Su CW; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan. Electronic address: .
Peng CY; Center for Digestive Medicine, Department of Internal Medicine, China Medical University Hospital, School of Medicine, China Medical University, Taichung, Taiwan. Electronic address: .
Chien RN; Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taiwan. Electronic address: .
Lin HH; Division of Gastroenterology and Hepatology, Taipei Tzu Chi Hospital, Taipei, Taiwan. Electronic address: .
Lo GH; Division of Gastroenterology, Department of Medical Research, E-DA Hospital, Kaohsiung, Taiwan. Electronic address: .
Su WW; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan. Electronic address: .
Kuo HT; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan. Electronic address: .
Hsu CW; Division of Hepatology, Department of Gastroenterology and Hepatology, Linkou Medical Center, Chang Gung Memorial Hospital, Taiwan. Electronic address: .
Yang SS; Liver Center, Cathay General Hospital Medical Center, Taipei, Taiwan. Electronic address: .
Yang SS; Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan. Electronic address: .
Tseng KC; PharmaEssentia Corp., Taipei, Taiwan. Electronic address: .
Qin A; PharmaEssentia Corp., Taipei, Taiwan. Electronic address: .
Huang YW; Liver Center, Cathay General Hospital Medical Center, Taipei, Taiwan; PharmaEssentia Corp., Taipei, Taiwan; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: .
Chuang WL; Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan. Electronic address: .
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Źródło :
Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2021 Mar; Vol. 120 (3), pp. 956-964. Date of Electronic Publication: 2020 Oct 16.
Typ publikacji :
Journal Article; Randomized Controlled Trial
MeSH Terms :
Hepatitis C, Chronic*/drug therapy
Antiviral Agents/adverse effects ; Drug Therapy, Combination ; Genotype ; Hepacivirus/genetics ; Humans ; Polyethylene Glycols/therapeutic use ; Recombinant Proteins/therapeutic use ; Ribavirin/therapeutic use ; Taiwan
Czasopismo naukowe
Tytuł :
Efficacy of ribavirin and interferon-α therapy for hospitalized patients with COVID-19: A multicenter, retrospective cohort study.
Autorzy :
Li H; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Xiong N; Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Li C; Department of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Gong Y; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Liu L; Office of Academic Research, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yang H; School of Nursing, Wuchang University of Technology, Wuhan, China.
Tan X; Lichuan Center for Disease Control and Prevention, Enshi Tujia and Miao Autonomous Prefecture, China.
Jiang N; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Zong Q; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Wang J; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Lu Z; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China.
Yin X; Department of Social Medicine and Health Management, School of Public Health, Huazhong University of Science and Technology, Wuhan, China. Electronic address: .
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Źródło :
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases [Int J Infect Dis] 2021 Mar; Vol. 104, pp. 641-648. Date of Electronic Publication: 2021 Jan 28.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
SARS-CoV-2*
Antiviral Agents/*administration & dosage
COVID-19/*drug therapy
Interferon-alpha/*administration & dosage
Ribavirin/*administration & dosage
Adult ; Aged ; COVID-19/mortality ; Drug Therapy, Combination ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Thapsigargin Is a Broad-Spectrum Inhibitor of Major Human Respiratory Viruses: Coronavirus, Respiratory Syncytial Virus and Influenza A Virus.
Autorzy :
Al-Beltagi S; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Preda CA; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Goulding LV; The Pirbright Institute, Ash Road, Pirbright, Woking GU24 0NF, UK.
James J; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Pu J; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Skinner P; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Jiang Z; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Wang BL; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Yang J; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Banyard AC; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Mellits KH; School of Biosciences, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
Gershkovich P; School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Hayes CJ; School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Nguyen-Van-Tam J; School of Medicine, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
Brown IH; Animal and Plant Health Agency (APHA), Weybridge, Woodham Lane, Addlestone KT15 3NB, UK.
Liu J; Key Laboratory of Animal Epidemiology, Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China.
Chang KC; School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, Nottingham LE12 5RD, UK.
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Źródło :
Viruses [Viruses] 2021 Feb 03; Vol. 13 (2). Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Betacoronavirus/*drug effects
Coronavirus OC43, Human/*drug effects
Influenza A Virus, H1N1 Subtype/*drug effects
Respiratory Syncytial Virus, Human/*drug effects
SARS-CoV-2/*drug effects
Thapsigargin/*pharmacology
Animals ; Antiviral Agents/therapeutic use ; Betacoronavirus/physiology ; Cell Line ; Cell Line, Tumor ; Cells, Cultured ; Coronavirus OC43, Human/physiology ; Endoplasmic Reticulum Stress ; Humans ; Influenza A Virus, H1N1 Subtype/physiology ; Mice ; Microbial Sensitivity Tests ; Orthomyxoviridae Infections/drug therapy ; Orthomyxoviridae Infections/virology ; Respiratory Syncytial Virus, Human/physiology ; Ribavirin/pharmacology ; SARS-CoV-2/physiology ; Thapsigargin/therapeutic use ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Lassa fever outcomes and prognostic factors in Nigeria (LASCOPE): a prospective cohort study.
Autorzy :
Duvignaud A; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, University Hospital Centre of Bordeaux, Hôpital Pellegrin, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire. Electronic address: .
Jaspard M; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire; The Alliance for International Medical Action, Dakar, Senegal.
Etafo IC; Lassa Fever Response Team, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
Gabillard D; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire.
Serra B; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire; The Alliance for International Medical Action, Dakar, Senegal.
Abejegah C; Lassa Fever Response Team, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
le Gal C; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire; The Alliance for International Medical Action, Dakar, Senegal.
Abidoye AT; Lassa Fever Response Team, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
Doutchi M; The Alliance for International Medical Action, Dakar, Senegal; Department of Infectious Diseases, National Hospital Centre of Zinder, Zinder, Niger.
Owhin S; Lassa Fever Response Team, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
Séri B; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire.
Vihundira JK; The Alliance for International Medical Action, Dakar, Senegal.
Bérerd-Camara M; The Alliance for International Medical Action, Dakar, Senegal.
Schaeffer J; The Alliance for International Medical Action, Dakar, Senegal.
Danet N; The Alliance for International Medical Action, Dakar, Senegal.
Augier A; The Alliance for International Medical Action, Dakar, Senegal.
Ogbaini-Emovon E; Institute of Lassa Fever Research and Control, Irrua Specialist Teaching Hospital, Irrua, Nigeria.
Salam AP; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Ahmed LA; Department of Family Medicine, Federal Medical Centre Owo, Owo, Nigeria.
Duraffour S; Department of Virology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Horby P; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Günther S; Department of Virology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany; German Center for Infection Research, Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Adedosu AN; Viral Hemorrhagic Fever Laboratory, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
Ayodeji OO; Lassa Fever Response Team, Infection Control and Research Centre, Federal Medical Centre Owo, Owo, Nigeria.
Anglaret X; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire.
Malvy D; Inserm 1219, University of Bordeaux, and French National Research Institute for Sustainable Development, Bordeaux, France; Department of Infectious Diseases and Tropical Medicine, Division of Tropical Medicine and Clinical International Health, University Hospital Centre of Bordeaux, Hôpital Pellegrin, Bordeaux, France; Programme PAC-CI/ANRS Research Site, University Hospital Centre of Treichville, Abidjan, Côte d'Ivoire.
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Corporate Authors :
LASCOPE study group
Źródło :
The Lancet. Global health [Lancet Glob Health] 2021 Apr; Vol. 9 (4), pp. e469-e478.
Typ publikacji :
Journal Article; Observational Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Palliative Care*
Lassa Fever/*mortality
Lassa virus/*isolation & purification
Ribavirin/*administration & dosage
Administration, Intravenous ; Adolescent ; Adult ; Age Factors ; Child ; Child, Preschool ; DNA, Viral/isolation & purification ; Female ; Follow-Up Studies ; Hospital Mortality ; Hospitalization/statistics & numerical data ; Humans ; Infant ; Infant, Newborn ; Kaplan-Meier Estimate ; Lassa Fever/diagnosis ; Lassa Fever/therapy ; Lassa Fever/virology ; Lassa virus/genetics ; Male ; Middle Aged ; Nigeria/epidemiology ; Pregnancy ; Prognosis ; Prospective Studies ; Reverse Transcriptase Polymerase Chain Reaction/statistics & numerical data ; Risk Factors ; Severity of Illness Index ; Time Factors ; Treatment Outcome ; Young Adult
Czasopismo naukowe
Tytuł :
Treatment of hepatitis C virus infection with direct-acting antivirals plus ribavirin eliminates viral RNA from peripheral blood mononuclear cells and reduces virologic relapse in diverse hepatic parenchymal changes.
Autorzy :
Abd Alla MDA; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt. .
Dawood RM; Department of Microbial Biotechnology, National Research Center, Cairo, Egypt.
Rashed HAE; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt.
Farrag G; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt.
Ammar IAE; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt.
Mahmoud MMA; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt.
Salum GM; Department of Microbial Biotechnology, National Research Center, Cairo, Egypt.
Altanbouly AMA; Department of Hepatology, Gastroenterology and Infectious Diseases, Faculty of Medicine, El-Hussein University Hospital, Al-Azhar University, Gouhar Al-Kaed Street, Al-Darasah, Cairo, 11675, Egypt.
El Meguid MA; Department of Microbial Biotechnology, National Research Center, Cairo, Egypt.
Awady MKE; Department of Microbial Biotechnology, National Research Center, Cairo, Egypt.
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Źródło :
Archives of virology [Arch Virol] 2021 Apr; Vol. 166 (4), pp. 1071-1081. Date of Electronic Publication: 2021 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antiviral Agents/*therapeutic use
Hepacivirus/*drug effects
Hepatitis C, Chronic/*drug therapy
RNA, Viral/*drug effects
Ribavirin/*therapeutic use
Adult ; Carbamates/therapeutic use ; Drug Therapy, Combination ; Female ; Hepacivirus/genetics ; Hepatitis C, Chronic/pathology ; Hepatitis C, Chronic/virology ; Humans ; Imidazoles/therapeutic use ; Leukocytes, Mononuclear/drug effects ; Leukocytes, Mononuclear/virology ; Liver/drug effects ; Liver/pathology ; Male ; Middle Aged ; Parenchymal Tissue/drug effects ; Parenchymal Tissue/pathology ; Pyrrolidines/therapeutic use ; RNA, Viral/analysis ; Secondary Prevention ; Sofosbuvir/therapeutic use ; Treatment Outcome ; Valine/analogs & derivatives ; Valine/therapeutic use
Czasopismo naukowe
Tytuł :
Sofosbuvir-based therapies associated with regression of liver fibrosis in patients with hepatitis C virus infection: A prospective observational study.
Autorzy :
Nozaki A; Gastroenterological Center, Yokohama City University Medical Center.
Chuma M; Gastroenterological Center, Yokohama City University Medical Center.
Hara K; Gastroenterological Center, Yokohama City University Medical Center.
Moriya S; Gastroenterological Center, Yokohama City University Medical Center.
Fukuda H; Gastroenterological Center, Yokohama City University Medical Center.
Numata K; Gastroenterological Center, Yokohama City University Medical Center.
Tanaka K; Gastroenterological Center, Yokohama City University Medical Center.
Morimoto M; Department of Hepatobiliary and Pancreatic Oncology, Kanagawa Cancer Center.
Sakamaki K; Center for Data Science.
Yamanaka T; Department of Biostatistics, School of Medicine, Yokohama City University.
Kondo M; Department of Gastroenterology, Yokohama City University Graduate School of Medicine.
Maeda S; Department of Gastroenterology, Yokohama City University Graduate School of Medicine.
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Źródło :
Medicine [Medicine (Baltimore)] 2021 Mar 26; Vol. 100 (12), pp. e25110.
Typ publikacji :
Journal Article; Observational Study
MeSH Terms :
Benzimidazoles/*administration & dosage
Fluorenes/*administration & dosage
Hepacivirus/*drug effects
Hepatitis C, Chronic/*drug therapy
Liver Cirrhosis/*drug therapy
Ribavirin/*administration & dosage
Sofosbuvir/*administration & dosage
Adult ; Aged ; Aged, 80 and over ; Drug Therapy, Combination ; Female ; Hepatitis C, Chronic/complications ; Humans ; Liver/drug effects ; Liver/virology ; Liver Cirrhosis/virology ; Male ; Middle Aged ; Prospective Studies ; Sustained Virologic Response ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Successful treatment of positive-sense RNA virus coinfection with autoimmune hepatitis using double filtration plasmapheresis.
Autorzy :
Kamimura H; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan .
Kamimura K; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Tsuchiya A; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Terai S; Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
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Źródło :
BMJ case reports [BMJ Case Rep] 2021 Mar 25; Vol. 14 (3). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Coinfection/*therapy
Coinfection/*virology
Hepatitis C, Chronic/*therapy
Hepatitis, Autoimmune/*therapy
Plasmapheresis/*methods
Antiviral Agents/therapeutic use ; COVID-19/complications ; COVID-19/therapy ; Drug Therapy, Combination ; Female ; Hepatitis C, Chronic/complications ; Hepatitis, Autoimmune/complications ; Humans ; Interferon alpha-2/therapeutic use ; Middle Aged ; Polyethylene Glycols/therapeutic use ; Positive-Strand RNA Viruses/isolation & purification ; Ribavirin/therapeutic use ; SARS-CoV-2 ; Treatment Outcome ; Viral Load
Czasopismo naukowe
Tytuł :
Prioritizing antiviral drugs against SARS-CoV-2 by integrating viral complete genome sequences and drug chemical structures.
Autorzy :
Peng L; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China.
Shen L; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China.
Xu J; College of Computer Science and Electronic Engineering, Hunan University, Changsha, 410082, China.
Tian X; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China.
Liu F; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China.
Wang J; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China.
Tian G; Geneis (Beijing) Co. Ltd., Beijing, 100102, China.
Yang J; Geneis (Beijing) Co. Ltd., Beijing, 100102, China. .
Zhou L; School of Computer Science, Hunan University of Technology, Zhuzhou, 412007, China. .
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Źródło :
Scientific reports [Sci Rep] 2021 Mar 18; Vol. 11 (1), pp. 6248. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Monophosphate/*analogs & derivatives
Alanine/*analogs & derivatives
Angiotensin-Converting Enzyme 2/*chemistry
Antiviral Agents/*chemistry
Ribavirin/*chemistry
Spike Glycoprotein, Coronavirus/*chemistry
Adenosine Monophosphate/chemistry ; Alanine/chemistry ; Aniline Compounds/chemistry ; Drug Evaluation, Preclinical ; Genome, Viral ; Molecular Docking Simulation ; SARS-CoV-2/genetics ; Sulfonamides/chemistry
Czasopismo naukowe
Tytuł :
COVID-19 and the burning issue of drug interaction: never forget the ECG.
Autorzy :
Sciaccaluga C; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy .
Cameli M; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Menci D; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Mandoli GE; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Sisti N; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Cameli P; Respiratory Diseases and Lung Transplantation, Department of Medicine, Surgery and Neurosciences, Siena University Hospital, Siena, Italy.
Franchi F; Department of Medicine, Surgery and Neuroscience, Anesthesia and Intensive Care Unit, University of Siena, Siena, Italy.
Mondillo S; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
Valente S; Department of Medical Biotechnologies, Section of Cardiology, University of Siena, Siena, Italy.
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Źródło :
Postgraduate medical journal [Postgrad Med J] 2021 Mar; Vol. 97 (1145), pp. 180-184. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antirheumatic Agents/*adverse effects
Antiviral Agents/*adverse effects
COVID-19/*drug therapy
Long QT Syndrome/*chemically induced
Adenosine Monophosphate/adverse effects ; Adenosine Monophosphate/analogs & derivatives ; Alanine/adverse effects ; Alanine/analogs & derivatives ; Antibodies, Monoclonal, Humanized/adverse effects ; Arrhythmias, Cardiac/chemically induced ; Chloroquine/adverse effects ; Drug Combinations ; Drug Interactions ; Electrocardiography ; Heart Failure ; Humans ; Hydroxychloroquine/adverse effects ; Hypoxia ; Inflammation ; Lopinavir/adverse effects ; Myocarditis ; Myocardium ; Precipitating Factors ; Receptors, Interleukin-6/antagonists & inhibitors ; Respiratory Distress Syndrome ; Ribavirin/adverse effects ; Ritonavir/adverse effects ; SARS-CoV-2 ; Water-Electrolyte Imbalance
SCR Protocol :
COVID-19 drug treatment
Czasopismo naukowe
Tytuł :
Effectiveness and safety of ledipasvir/sofosbuvir for genotype 2 chronic hepatitis C infection: Real-world experience from Taiwan.
Autorzy :
Chiu HC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chiu YC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yang EH; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chang TT; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chien SC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu IC; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Wu CH; Department of Internal Medicine, Tainan Hospital, Ministry of Health and Welfare, Tainan, Taiwan.
Cheng PN; Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address: .
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Źródło :
Journal of the Formosan Medical Association = Taiwan yi zhi [J Formos Med Assoc] 2021 Mar; Vol. 120 (3), pp. 983-990. Date of Electronic Publication: 2020 Sep 03.
Typ publikacji :
Journal Article
MeSH Terms :
Hepatitis C, Chronic*/drug therapy
Antiviral Agents/adverse effects ; Benzimidazoles ; Drug Therapy, Combination ; Fluorenes ; Genotype ; Hepacivirus/genetics ; Humans ; Ribavirin/therapeutic use ; Sofosbuvir/adverse effects ; Taiwan ; Treatment Outcome
Czasopismo naukowe

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