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Wyświetlanie 1-18 z 18
Tytuł :
Repression of IFN-gamma expression by peroxisome proliferator-activated receptor gamma.
Autorzy :
Cunard R; Research Service and Division of Nephrology-Hypertension, University of California and Veterans Affairs San Diego Healthcare System 151, 3350 La Jolla Village Drive, San Diego, CA 92161, USA. />Eto Y
Muljadi JT
Glass CK
Kelly CJ
Ricote M
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2004 Jun 15; Vol. 172 (12), pp. 7530-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Down-Regulation*
Interferon-gamma/*antagonists & inhibitors
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Animals ; CD4-Positive T-Lymphocytes/chemistry ; CD8-Positive T-Lymphocytes/chemistry ; Humans ; Interferon-gamma/biosynthesis ; Interferon-gamma/genetics ; Jurkat Cells ; Ligands ; Mice ; Mice, Inbred BALB C ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-jun/metabolism ; Receptors, Cytoplasmic and Nuclear/biosynthesis ; Receptors, Cytoplasmic and Nuclear/genetics ; Spleen/cytology ; Transcription Factors/biosynthesis ; Transcription Factors/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł :
Decoding transcriptional programs regulated by PPARs and LXRs in the macrophage: effects on lipid homeostasis, inflammation, and atherosclerosis.
Autorzy :
Ricote M; Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, Calif 92093-0651, USA.
Valledor AF
Glass CK
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2004 Feb; Vol. 24 (2), pp. 230-9. Date of Electronic Publication: 2003 Oct 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Arteriosclerosis/*physiopathology
Homeostasis/*physiology
Lipids/*physiology
Macrophages/*chemistry
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Transcription, Genetic/*physiology
Animals ; DNA-Binding Proteins ; Humans ; Inflammation/physiopathology ; Liver X Receptors ; Macrophages/metabolism ; Orphan Nuclear Receptors
Czasopismo naukowe
Tytuł :
PPARgamma and PPARdelta negatively regulate specific subsets of lipopolysaccharide and IFN-gamma target genes in macrophages.
Autorzy :
Welch JS; Department of Cellular and Molecular Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla 92093-0651, USA.
Ricote M
Akiyama TE
Gonzalez FJ
Glass CK
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2003 May 27; Vol. 100 (11), pp. 6712-7. Date of Electronic Publication: 2003 May 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Gene Expression Profiling*
Interferon-gamma/*metabolism
Lipopolysaccharides/*metabolism
Macrophages, Peritoneal/*metabolism
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Base Sequence ; DNA Primers ; Gene Expression Regulation/drug effects ; Lipopolysaccharides/pharmacology ; Promoter Regions, Genetic
Czasopismo naukowe
Tytuł :
WY14,643, a PPAR alpha ligand, has profound effects on immune responses in vivo.
Autorzy :
Cunard R; Research Service, Veterans Affairs San Diego Healthcare System, Department of Medicine, University of California, San Diego, CA 92161, USA. />DiCampli D
Archer DC
Stevenson JL
Ricote M
Glass CK
Kelly CJ
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2002 Dec 15; Vol. 169 (12), pp. 6806-12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Immunosuppressive Agents/*administration & dosage
Immunosuppressive Agents/*metabolism
Peroxisome Proliferators/*administration & dosage
Peroxisome Proliferators/*metabolism
Peroxisomes/*metabolism
Pyrimidines/*administration & dosage
Pyrimidines/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Transcription Factors/*metabolism
Administration, Oral ; Animals ; Antibody Formation/drug effects ; Apoptosis/drug effects ; Apoptosis/immunology ; B-Lymphocyte Subsets/cytology ; B-Lymphocyte Subsets/drug effects ; B-Lymphocyte Subsets/immunology ; B-Lymphocyte Subsets/metabolism ; Cell Death/drug effects ; Cell Death/immunology ; Cytokines/antagonists & inhibitors ; Cytokines/biosynthesis ; Glycoproteins/administration & dosage ; Glycoproteins/immunology ; Growth Inhibitors/administration & dosage ; Ligands ; Lymphocyte Count ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Myelin-Oligodendrocyte Glycoprotein ; Peptide Fragments/administration & dosage ; Peptide Fragments/immunology ; Receptors, Cytoplasmic and Nuclear/biosynthesis ; Receptors, Cytoplasmic and Nuclear/deficiency ; Receptors, Cytoplasmic and Nuclear/genetics ; Spleen/cytology ; Spleen/drug effects ; Spleen/pathology ; T-Lymphocyte Subsets/drug effects ; T-Lymphocyte Subsets/pathology ; Transcription Factors/biosynthesis ; Transcription Factors/deficiency ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Immunohistochemical detection of the retinoid acid receptors (RXR-alpha, -beta, -gamma) and Farnesoid X-activated receptor (FXR) in the marbled newt along the annual cycle.
Autorzy :
Alfaro JM; Department of Cell Biology and Genetics, University of Alcalá, Madrid, Spain.
Ricote M
Lobo MV
Royuela M
Fraile B
Paniagua R
Arenas MI
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Źródło :
Molecular reproduction and development [Mol Reprod Dev] 2002 Jun; Vol. 62 (2), pp. 216-22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*analysis
Receptors, Cytoplasmic and Nuclear/*analysis
Receptors, Retinoic Acid/*analysis
Testis/*chemistry
Transcription Factors/*analysis
Animals ; Blotting, Western/methods ; Immunoenzyme Techniques ; Male ; Retinoid X Receptors ; Salamandridae
Czasopismo naukowe
Tytuł :
Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.
Autorzy :
Akiyama TE; Laboratory of Metabolism, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Sakai S
Lambert G
Nicol CJ
Matsusue K
Pimprale S
Lee YH
Ricote M
Glass CK
Brewer HB Jr
Gonzalez FJ
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2002 Apr; Vol. 22 (8), pp. 2607-19.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP-Binding Cassette Transporters/*genetics
Apolipoproteins E/*genetics
Cholesterol/*metabolism
Macrophages/*metabolism
Receptors, Cytoplasmic and Nuclear/*deficiency
Receptors, Cytoplasmic and Nuclear/*genetics
Transcription Factors/*deficiency
Transcription Factors/*genetics
ATP Binding Cassette Transporter 1 ; ATP Binding Cassette Transporter, Subfamily G, Member 1 ; Alleles ; Animals ; Biological Transport, Active ; Exons ; Female ; Gene Expression/drug effects ; Gene Targeting ; Integrases/genetics ; Lipoprotein Lipase/genetics ; Macrophages/drug effects ; Mice ; Mice, Knockout ; Mice, Transgenic ; Poly I-C/pharmacology ; Pregnancy ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Cytoplasmic and Nuclear/metabolism ; Sequence Deletion ; Transcription Factors/metabolism ; Viral Proteins/genetics
Czasopismo naukowe
Tytuł :
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors.
Autorzy :
Cunard R; Research Service, Veterans Affairs San Diego Healthcare System, Department of Cellular and Molecular Medicine, University of California, San Diego, CA 92161, USA. />Ricote M
DiCampli D
Archer DC
Kahn DA
Glass CK
Kelly CJ
Pokaż więcej
Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2002 Mar 15; Vol. 168 (6), pp. 2795-802.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Thiazolidinediones*
Cytokines/*biosynthesis
Receptors, Cytoplasmic and Nuclear/*metabolism
Transcription Factors/*metabolism
Adjuvants, Immunologic/metabolism ; Adjuvants, Immunologic/pharmacology ; Animals ; Concanavalin A/pharmacology ; Cytokines/metabolism ; Female ; Interleukin-4/genetics ; Interleukin-4/physiology ; Ligands ; Lymphocyte Activation/drug effects ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Microbodies/metabolism ; Promoter Regions, Genetic/drug effects ; Promoter Regions, Genetic/immunology ; Pyrimidines/metabolism ; Pyrimidines/pharmacology ; RNA, Messenger/biosynthesis ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Cytoplasmic and Nuclear/physiology ; Receptors, IgE/biosynthesis ; Spleen/cytology ; Spleen/immunology ; Spleen/metabolism ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Thiazoles/metabolism ; Thiazoles/pharmacology ; Transcription Factors/genetics ; Transcription Factors/physiology ; Up-Regulation/drug effects ; Up-Regulation/genetics ; Up-Regulation/immunology
Czasopismo naukowe
Tytuł :
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription.
Autorzy :
Llopis J; Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Westin S
Ricote M
Wang Z
Cho CY
Kurokawa R
Mullen TM
Rose DW
Rosenfeld MG
Tsien RY
Glass CK
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2000 Apr 11; Vol. 97 (8), pp. 4363-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Transcription, Genetic*
Carrier Proteins/*metabolism
Receptors, Estrogen/*metabolism
Receptors, Retinoic Acid/*metabolism
Transcription Factors/*metabolism
Cell Nucleus/metabolism ; Energy Transfer ; Fluorescence ; Green Fluorescent Proteins ; HeLa Cells ; Histone Acetyltransferases ; Humans ; Ligands ; Luminescent Proteins/metabolism ; Mediator Complex Subunit 1 ; Molecular Sequence Data ; Nuclear Receptor Coactivator 1 ; Protein Binding
Czasopismo naukowe
Tytuł :
Regulation of macrophage gene expression by the peroxisome proliferator-activated receptor-gamma.
Autorzy :
Ricote M; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093-0651, USA. />Welch JS
Glass CK
Pokaż więcej
Źródło :
Hormone research [Horm Res] 2000; Vol. 54 (5-6), pp. 275-80.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Gene Expression Regulation/*physiology
Macrophages/*physiology
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Animals ; Arachidonate 12-Lipoxygenase/metabolism ; Arachidonate 15-Lipoxygenase/metabolism ; CD36 Antigens/genetics ; Cell Line ; Down-Regulation ; Gene Expression/drug effects ; Interleukin-4/pharmacology ; Macrophages/drug effects ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type II ; Transcription, Genetic/drug effects ; Transcription, Genetic/physiology
Czasopismo naukowe
Tytuł :
The peroxisome proliferator-activated receptor(PPARgamma) as a regulator of monocyte/macrophage function.
Autorzy :
Ricote M; Division of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, USA.
Huang JT
Welch JS
Glass CK
Pokaż więcej
Źródło :
Journal of leukocyte biology [J Leukoc Biol] 1999 Nov; Vol. 66 (5), pp. 733-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Macrophages/*immunology
Monocytes/*immunology
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Animals ; Arteriosclerosis/immunology ; Gene Expression ; Humans ; Ligands ; Neoplasms/immunology ; Peroxisomes ; Receptors, Cytoplasmic and Nuclear/genetics ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase.
Autorzy :
Huang JT; Department and School of Medicine, University of California, San Diego, La Jolla 92093-0651, USA.
Welch JS
Ricote M
Binder CJ
Willson TM
Kelly C
Witztum JL
Funk CD
Conrad D
Glass CK
Pokaż więcej
Źródło :
Nature [Nature] 1999 Jul 22; Vol. 400 (6742), pp. 378-82.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Arachidonate 12-Lipoxygenase/*metabolism
Arachidonate 15-Lipoxygenase/*metabolism
CD36 Antigens/*genetics
Interleukin-4/*physiology
Macrophages/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Transcription Factors/*metabolism
Animals ; CD36 Antigens/biosynthesis ; Cell Line ; Gene Expression Regulation ; Humans ; Ligands ; Mice ; Mice, Knockout ; Receptors, Cytoplasmic and Nuclear/biosynthesis ; Receptors, Cytoplasmic and Nuclear/genetics ; Transcription Factors/biosynthesis ; Transcription Factors/genetics
Czasopismo naukowe
Tytuł :
Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein.
Autorzy :
Ricote M; Division of Cellular and Molecular Medicine, Department of Medicine, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0651, USA.
Huang J
Fajas L
Li A
Welch J
Najib J
Witztum JL
Auwerx J
Palinski W
Glass CK
Pokaż więcej
Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1998 Jun 23; Vol. 95 (13), pp. 7614-9.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Arteriosclerosis/*metabolism
Colony-Stimulating Factors/*metabolism
Foam Cells/*metabolism
Lipoproteins, LDL/*metabolism
Receptors, Cytoplasmic and Nuclear/*biosynthesis
Transcription Factors/*biosynthesis
Animals ; Cell Differentiation ; Cells, Cultured ; Foam Cells/drug effects ; Humans ; Mice ; Promoter Regions, Genetic ; Protein Kinase C/antagonists & inhibitors ; Tetradecanoylphorbol Acetate/pharmacology
Czasopismo naukowe
Tytuł :
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation.
Autorzy :
Ricote M; Department of Medicine, University of California, San Diego, La Jolla 92093-0651, USA.
Li AC
Willson TM
Kelly CJ
Glass CK
Pokaż więcej
Źródło :
Nature [Nature] 1998 Jan 01; Vol. 391 (6662), pp. 79-82.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Macrophage Activation/*physiology
Macrophages/*physiology
Receptors, Cytoplasmic and Nuclear/*physiology
Transcription Factors/*physiology
Bone Marrow Cells/physiology ; Collagenases/biosynthesis ; Gene Expression Regulation ; HeLa Cells ; Humans ; Inflammation Mediators/physiology ; Macrophages, Peritoneal/physiology ; Matrix Metalloproteinase 9 ; Nitric Oxide Synthase/biosynthesis ; Nitric Oxide Synthase/genetics ; Promoter Regions, Genetic ; Prostaglandin D2/analogs & derivatives ; Prostaglandin D2/physiology ; Receptors, Cytoplasmic and Nuclear/genetics ; Transcription Factors/genetics ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.
Autorzy :
DiRenzo J; Department of Medicine, University of California, San Diego, La Jolla 92093-0651, USA.
Söderstrom M
Kurokawa R
Ogliastro MH
Ricote M
Ingrey S
Hörlein A
Rosenfeld MG
Glass CK
Pokaż więcej
Źródło :
Molecular and cellular biology [Mol Cell Biol] 1997 Apr; Vol. 17 (4), pp. 2166-76.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Microbodies/*metabolism
Receptors, Cytoplasmic and Nuclear/*metabolism
Receptors, Retinoic Acid/*metabolism
Transcription Factors/*metabolism
Animals ; Base Sequence ; Binding Sites/genetics ; Cell Line ; DNA/genetics ; DNA/metabolism ; Dimerization ; Histone Acetyltransferases ; Ligands ; Mice ; Models, Biological ; Mutation ; Nuclear Receptor Coactivator 1 ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Retinoic Acid/chemistry ; Receptors, Retinoic Acid/genetics ; Retinoid X Receptors ; Signal Transduction ; Transcription Factors/chemistry ; Transcription Factors/genetics ; Transfection
Czasopismo naukowe
    Wyświetlanie 1-18 z 18

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