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    Wyświetlanie 1-5 z 5
    Tytuł:
    Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers--role of estrogen receptor and HER2 reactivation.
    Autorzy:
    Wang YC
    Morrison G
    Gillihan R
    Guo J
    Ward RM
    Fu X
    Botero MF
    Healy NA
    Hilsenbeck SG
    Phillips GL
    Chamness GC
    Rimawi MF
    Osborne CK
    Schiff R
    Wang, Yen-Chao
    Morrison, Gladys
    Gillihan, Ryan
    Guo, Jun
    Ward, Robin M
    Fu, Xiaoyong
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    Źródło:
    Breast Cancer Research; 2011, Vol. 13 Issue 6, pR121-R121, 1p
    Czasopismo naukowe
    Szczegóły
    Tytuł:
    Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors.
    Autorzy:
    Lv X; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Lu X; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Cao J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Luo Q; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Ding Y; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Peng F; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Pataer A; Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Lu D; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA.
    Han D; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Malmberg E; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Chan DW; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Wang X; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Savage SR; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
    Mao S; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Yu J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Peng F; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX 77030, USA.
    Yan L; Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Meng H; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
    Maneix L; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Huffington Center on Aging, Baylor College of Medicine, USA.
    Han Y; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Chen Y; Department of Bioinformatics and Computational Biology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Yao W; Department of Translational Molecular Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Chang EC; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Catic A; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Huffington Center on Aging, Baylor College of Medicine, USA.
    Lin X; Division of Surgical Oncology, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
    Miles G; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
    Huang P; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
    Sun Z; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX 77030, USA.
    Burt B; Division of Thoracic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
    Wang H; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Wang J; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA.
    Yao QC; Division of Surgical Oncology, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
    Zhang B; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.
    Roth JA; Department of Thoracic and Cardiovascular Surgery, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    O'Malley BW; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
    Ellis MJ; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Early Oncology, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA.
    Rimawi MF; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
    Ying H; Department of Molecular and Cellular Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
    Chen X; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.; Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.
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    Źródło:
    Science (New York, N.Y.) [Science] 2023 Sep 08; Vol. 381 (6662), pp. eabn4180. Date of Electronic Publication: 2023 Sep 08.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Endoribonucleases*
    Extracellular Signal-Regulated MAP Kinases*
    Neoplasms*/drug therapy
    Neoplasms*/genetics
    Proteostasis*
    Proto-Oncogene Proteins p21(ras)*/antagonists & inhibitors
    Proto-Oncogene Proteins p21(ras)*/genetics
    Drug Resistance, Neoplasm*
    Enzyme Inhibitors*/pharmacology
    Antineoplastic Agents*/pharmacology
    Heat Shock Transcription Factors*/metabolism
    Humans ; Protein Serine-Threonine Kinases
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Lumpectomy followed by radiation improves survival in HER2 positive and triple-negative breast cancer with high tumor-infiltrating lymphocytes compared to mastectomy alone.
    Autorzy:
    Mouabbi JA; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
    Chand M; Ascension St John Hospital, Detroit, MI, USA.
    Asghar IA; Ascension St John Hospital, Detroit, MI, USA.
    Sakhi R; Ascension St John Hospital, Detroit, MI, USA.
    Ockner D; Ascension St John Hospital, Detroit, MI, USA.
    Dul CL; Ascension St John Hospital, Detroit, MI, USA.
    Hadid T; Ascension St John Hospital, Detroit, MI, USA.
    Aref A; Ascension St John Hospital, Detroit, MI, USA.
    Rimawi MF; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
    Hoyos V; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX, USA.
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    Źródło:
    Cancer medicine [Cancer Med] 2021 Jul; Vol. 10 (14), pp. 4790-4795. Date of Electronic Publication: 2021 Jun 03.
    Typ publikacji:
    Comparative Study; Journal Article
    MeSH Terms:
    Breast Neoplasms*/chemistry
    Breast Neoplasms*/immunology
    Breast Neoplasms*/mortality
    Breast Neoplasms*/therapy
    Lymphocytes, Tumor-Infiltrating*
    Mastectomy, Segmental*/mortality
    Receptor, ErbB-2*
    Adult ; Age Factors ; Aged ; Aged, 80 and over ; Antineoplastic Agents/therapeutic use ; Combined Modality Therapy/methods ; Combined Modality Therapy/mortality ; Disease-Free Survival ; Female ; Humans ; Kaplan-Meier Estimate ; Mastectomy/mortality ; Middle Aged ; Neoplasm Recurrence, Local ; Neoplasm Staging ; Radiotherapy/mortality ; Retrospective Studies ; Time Factors ; Triple Negative Breast Neoplasms/chemistry ; Triple Negative Breast Neoplasms/immunology ; Triple Negative Breast Neoplasms/mortality ; Triple Negative Breast Neoplasms/therapy
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Endocrine-Based Treatments in Clinically-Relevant Subgroups of Hormone Receptor-Positive/HER2-Negative Metastatic Breast Cancer: Systematic Review and Meta-Analysis.
    Autorzy:
    Schettini F; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', 80131 Naples, Italy.; Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, 08036 Barcelona, Spain.; SOLTI Breast Cancer Research Group, 08008 Barcelona, Spain.
    Giuliano M; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', 80131 Naples, Italy.
    Giudici F; Unit of Biostatistics, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
    Conte B; Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, 08036 Barcelona, Spain.; Breast Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
    De Placido P; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', 80131 Naples, Italy.
    Venturini S; Department of Management, University of Turin, 10124 Turin, Italy.; Centre for Research on Health and Social Care Management (CERGAS), SDA Bocconi School of Management, 20136 Milan, Italy.
    Rognoni C; Centre for Research on Health and Social Care Management (CERGAS), SDA Bocconi School of Management, 20136 Milan, Italy.
    Di Leo A; 'Sandro Pitigliani' Medical Oncology Department, Hospital of Prato, 59100 Prato, Italy.
    Locci M; Department of Neuroscience, Reproductive Medicine and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
    Jerusalem G; Medical Oncology Department, Centre Hospitalier Universitaire de Liège and Liège University, 4000 Liège, Belgium.
    Del Mastro L; Breast Unit, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.; Department of Internal Medicine and Medical Specialties (DIMI), School of Medicine, University of Genoa, 16132 Genoa, Italy.
    Puglisi F; Department of Medicine, University of Udine, 33100 Udine, Italy.; IRCCS Centro di Riferimento Oncologico Aviano, National Cancer Institute, 33081 Aviano, Italy.
    Conte P; Department of Surgery, Oncology and Gastroenterology, University of Padova, 35122 Padova, Italy.; Division of Medical Oncology 2, Istituto Oncologico Veneto-IRCCSS, 35128 Padova, Italy.
    De Laurentiis M; Breast Oncology Unit, INT-Fondazione 'G. Pascale', 80131 Naples, Italy.
    Pusztai L; Department of Medicine, Yale University School of Medicine, New Haven, CT 06510, USA.
    Rimawi MF; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
    Schiff R; Dan L Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
    Arpino G; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', 80131 Naples, Italy.
    De Placido S; Department of Clinical Medicine and Surgery, University of Naples 'Federico II', 80131 Naples, Italy.
    Prat A; Translational Genomics and Targeted Therapies in Solid Tumors, IDIBAPS, 08036 Barcelona, Spain.; SOLTI Breast Cancer Research Group, 08008 Barcelona, Spain.; Department of Medical Oncology, Hospital Clínic, 08036 Barcelona, Spain.
    Generali D; Department of Medical, Surgery and Health Sciences, University of Trieste, 34127 Trieste, Italy.; Breast Cancer Unit, Azienda Socio Sanitaria Territoriale di Cremona, 26100 Cremona, Italy.
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    Źródło:
    Cancers [Cancers (Basel)] 2021 Mar 22; Vol. 13 (6). Date of Electronic Publication: 2021 Mar 22.
    Typ publikacji:
    Journal Article; Review
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-5 z 5

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