SOX9 switch links regeneration to fibrosis at the single-cell level in mammalian kidneys.
Autorzy:
Aggarwal S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Wang Z; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. RinconFernandezPachecoD; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Rinaldi A; Division of Nephrology, Ente Ospedaliero Cantonale, CH-6900 Lugano, Switzerland. Rajewski A; Applied Genomics, Computation, and Translational Core, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Callemeyn J; Department of Microbiology, Immunology and Transplantation, KU Leuven, BE-3000 Leuven, Belgium. Van Loon E; Department of Microbiology, Immunology and Transplantation, KU Leuven, BE-3000 Leuven, Belgium. Lamarthée B; Department of Microbiology, Immunology and Transplantation, KU Leuven, BE-3000 Leuven, Belgium. Covarrubias AE; Division of Nephrology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Hou J; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Yamashita M; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Akiyama H; Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Gifu 501-1194, Japan. Karumanchi SA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Division of Nephrology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Svendsen CN; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Noble PW; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Jordan SC; Division of Nephrology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Breunig JJ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Naesens M; Department of Microbiology, Immunology and Transplantation, KU Leuven, BE-3000 Leuven, Belgium. Cippà PE; Division of Nephrology, Ente Ospedaliero Cantonale, CH-6900 Lugano, Switzerland.; Faculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland. Kumar S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.; Division of Nephrology, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
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Źródło:
Science (New York, N.Y.) [Science] 2024 Feb 23; Vol. 383 (6685), pp. eadd6371. Date of Electronic Publication: 2024 Feb 23.
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