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Wyszukujesz frazę ""Rna-polymerase"" wg kryterium: Temat


Tytuł:
Expression of RNA polymerase I catalytic core is influenced by RPA12.
Autorzy:
Ford BL; Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Wei T; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.
Liu H; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Scull CE; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Najmi SM; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Pitts S; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Fan W; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
Schneider DA; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Laiho M; Department of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
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Źródło:
PloS one [PLoS One] 2023 May 11; Vol. 18 (5), pp. e0285660. Date of Electronic Publication: 2023 May 11 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Chromatin*
RNA Polymerase I*/genetics
RNA Polymerase I*/metabolism
Humans ; Catalytic Domain ; RNA Polymerase II/metabolism ; Transcription, Genetic ; Neoplasms/genetics ; Neoplasms/metabolism
Czasopismo naukowe
Tytuł:
Mechanisms and Functions of the RNA Polymerase II General Transcription Machinery during the Transcription Cycle.
Autorzy:
Archuleta SR; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
Goodrich JA; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
Kugel JF; Department of Biochemistry, University of Colorado Boulder, 596 UCB, Boulder, CO 80309, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 01; Vol. 14 (2). Date of Electronic Publication: 2024 Feb 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
RNA Polymerase II*/chemistry
Transcription, Genetic*
Humans ; Transcription Factors/metabolism ; Promoter Regions, Genetic ; RNA, Messenger
Czasopismo naukowe
Tytuł:
Discovering new potential inhibitors to SARS-CoV-2 RNA dependent RNA polymerase (RdRp) using high throughput virtual screening and molecular dynamics simulations.
Autorzy:
Brunt D; College of Science and Mathematics, Rowan University, Glassboro, NJ, 08028, USA.
Lakernick PM; College of Science and Mathematics, Rowan University, Glassboro, NJ, 08028, USA.
Wu C; College of Science and Mathematics, Rowan University, Glassboro, NJ, 08028, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Nov 21; Vol. 12 (1), pp. 19986. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Coronavirus RNA-Dependent RNA Polymerase*
COVID-19 Drug Treatment*
Humans ; Molecular Dynamics Simulation ; RNA, Viral ; SARS-CoV-2 ; Adenosine Triphosphate ; RNA-Dependent RNA Polymerase ; Zinc
Czasopismo naukowe
Tytuł:
ZmELP1, an Elongator complex subunit, is required for the maintenance of histone acetylation and RNA Pol II phosphorylation in maize kernels.
Autorzy:
Li J; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Gu W; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.; Crop Breeding, Cultivation Research Institution/CIMMYT-China Specialty Maize Research Center, Shanghai Engineering Research Center of Specialty Maize, Shanghai Key Laboratory of Agricultural Genetics and Breeding, Shanghai Academy of Agricultural Sciences, Shanghai, China.
Yang Z; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Chen J; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Yi F; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.; Engineering Research Center of Plant Growth Regulator, Ministry of Education, College of Agronomy and Biotechnology, China Agricultural University, Beijing, China.
Li T; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Li J; State Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing, China.
Zhou Y; State Key Laboratory of Protein and Plant Gene Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Guo Y; State Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing, China.
Song W; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Lai J; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
Zhao H; State Key Laboratory of Maize Bio-breeding, National Maize Improvement Center, Frontiers Science Center for Molecular Design Breeding, Department of Plant Genetics and Breeding, China Agricultural University, Beijing, China.
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Źródło:
Plant biotechnology journal [Plant Biotechnol J] 2024 May; Vol. 22 (5), pp. 1251-1268. Date of Electronic Publication: 2023 Dec 15.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
Histones*/metabolism
Zea mays/genetics ; Zea mays/metabolism ; Phosphorylation ; Acetylation ; Genome-Wide Association Study ; Saccharomyces cerevisiae/genetics
Czasopismo naukowe
Tytuł:
Utilization of Bacteriophage phi6 for the Production of High-Quality Double-Stranded RNA Molecules.
Autorzy:
Levanova AA; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
Poranen MM; Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, University of Helsinki, 00014 Helsinki, Finland.
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Źródło:
Viruses [Viruses] 2024 Jan 22; Vol. 16 (1). Date of Electronic Publication: 2024 Jan 22.
Typ publikacji:
Journal Article; Review
MeSH Terms:
RNA, Double-Stranded*/genetics
RNA-Dependent RNA Polymerase*/genetics
RNA-Dependent RNA Polymerase*/metabolism
RNA Interference ; Nucleotidyltransferases/genetics
Czasopismo naukowe
Tytuł:
The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 Pandemic.
Autorzy:
Comunale BA; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Larson RJ; Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.; Department of Palliative Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
Jackson-Ward E; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.; Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.
Singh A; Department of Biological Sciences, University of California San Diego, La Jolla, CA 92161, USA.
Koback FL; Geisel School of Medicine at Dartmouth, Hanover, NH 03755, USA.
Engineer LD; Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.; Department of Anesthesiology and Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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Źródło:
Viruses [Viruses] 2023 Nov 25; Vol. 15 (12). Date of Electronic Publication: 2023 Nov 25.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
Antiviral Agents*/metabolism
COVID-19*/genetics
COVID-19*/metabolism
RNA-Dependent RNA Polymerase*/drug effects
RNA-Dependent RNA Polymerase*/genetics
Humans ; Membrane Proteins ; Molecular Docking Simulation ; Pandemics ; SARS-CoV-2/metabolism ; COVID-19 Drug Treatment/methods
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells.
Autorzy:
Cho HI; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.; Initiative for Biological Function & Systems, Yonsei University, Seoul, 03722, Republic of Korea.
Jo S; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.; Initiative for Biological Function & Systems, Yonsei University, Seoul, 03722, Republic of Korea.
Kim MS; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Kim HB; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.; Department of Neurology, Institute for Cell Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD, 21205, USA.
Liu X; Department of Pathology, Yanbian University College of Medicine, No.977, Gongyuan Road, Yanji, 133002, China.
Xuan Y; Department of Pathology, Yanbian University College of Medicine, No.977, Gongyuan Road, Yanji, 133002, China. .
Cho JW; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. .; Interdisciplinary Program of Integrated OMICS for Biomedical Science, Graduate School, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. .
Jang YK; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. .; Initiative for Biological Function & Systems, Yonsei University, Seoul, 03722, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 14; Vol. 13 (1), pp. 19885. Date of Electronic Publication: 2023 Nov 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
Colorectal Neoplasms*/genetics
Humans ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; N-Acetylglucosaminyltransferases/metabolism ; Catalysis ; Protein Processing, Post-Translational ; Methyltransferases/metabolism
Czasopismo naukowe
Tytuł:
RNA Pol II Assembly Affects ncRNA Expression.
Autorzy:
Garrido-Godino AI; Departamento de Biología Experimental-Genética, Universidad de Jaén, Paraje de las Lagunillas, s/n, E-23071 Jaén, Spain.
Gupta I; Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Meyerhofstraße 1, 69117 Heidelberg, Germany.
Pelechano V; SciLifeLab, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 171 65 Solna, Sweden.
Navarro F; Departamento de Biología Experimental-Genética, Universidad de Jaén, Paraje de las Lagunillas, s/n, E-23071 Jaén, Spain.; Instituto Universitario de Investigación en Olivar y Aceites de Oliva (INUO), Universidad de Jaén, Paraje de las Lagunillas, s/n, E-23071 Jaén, Spain.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Dec 29; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Polymerase II*/genetics
Exosomes*
Humans ; Transcription, Genetic ; RNA, Untranslated/genetics ; Translocation, Genetic
Czasopismo naukowe
Tytuł:
A fungal RNA-dependent RNA polymerase is a novel player in plant infection and cross-kingdom RNA interference.
Autorzy:
Cheng AP; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Lederer B; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Oberkofler L; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Huang L; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Johnson NR; Centro de Genómica y Bioinformática, Facultad de Ciencias, Ingeniería y Tecnología, Universidad Mayor, Santiago, Chile.; ANID-Millennium Science Initiative Program-Millennium Institute for Integrative Biology (iBio), Santiago, Chile.
Platten F; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Dunker F; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Tisserant C; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
Weiberg A; Institute of Genetics, Faculty of Biology, Ludwig Maximilian University of Munich, Martinsried, Germany.
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Źródło:
PLoS pathogens [PLoS Pathog] 2023 Dec 20; Vol. 19 (12), pp. e1011885. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2023).
Typ publikacji:
Journal Article
MeSH Terms:
RNA-Dependent RNA Polymerase*/genetics
Arabidopsis*/genetics
Arabidopsis*/microbiology
RNA Interference ; RNA, Small Interfering/genetics ; Virulence/genetics ; Plants/genetics ; Botrytis/genetics ; Plant Diseases/genetics ; Plant Diseases/microbiology ; RNA, Fungal/genetics ; RNA, Plant
Czasopismo naukowe
Tytuł:
A Sensitive, Cell-Based Assay for Measuring Low-Level Biological Activity of α-Amanitin.
Autorzy:
Rasooly R; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Do P; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
He X; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
Hernlem B; Foodborne Toxin Detection & Prevention Research Unit, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, Albany, CA 94710, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 16; Vol. 24 (22). Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Alpha-Amanitin*/pharmacology
RNA Polymerase II*
Animals ; Chlorocebus aethiops ; Humans ; Vero Cells ; HEK293 Cells ; Amanita
Czasopismo naukowe
Tytuł:
Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure.
Autorzy:
Nagy-Mikó B; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Németh-Szatmári O; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Faragó-Mészáros R; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Csókási A; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.
Bognár B; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Ördög N; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.
Borsos BN; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.
Majoros H; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.; Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Dugonics tér 13, H-6720 Szeged, Hungary.
Ujfaludi Z; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.; Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Dugonics tér 13, H-6720 Szeged, Hungary.
Oláh-Németh O; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.
Nikolényi A; Department of Oncotherapy, Albert Szent-Györgyi Health Centre, University of Szeged, 12 Korányi Fasor, H-6720 Szeged, Hungary.
Dobi Á; Department of Oncotherapy, Albert Szent-Györgyi Health Centre, University of Szeged, 12 Korányi Fasor, H-6720 Szeged, Hungary.
Kószó R; Department of Oncotherapy, Albert Szent-Györgyi Health Centre, University of Szeged, 12 Korányi Fasor, H-6720 Szeged, Hungary.
Sántha D; Department of Oncotherapy, Albert Szent-Györgyi Health Centre, University of Szeged, 12 Korányi Fasor, H-6720 Szeged, Hungary.
Lázár G; Department of Surgery, Albert Szent-Györgyi Health Centre, University of Szeged, 8 Semmelweis Street, H-6725 Szeged, Hungary.
Simonka Z; Department of Surgery, Albert Szent-Györgyi Health Centre, University of Szeged, 8 Semmelweis Street, H-6725 Szeged, Hungary.
Paszt A; Department of Surgery, Albert Szent-Györgyi Health Centre, University of Szeged, 8 Semmelweis Street, H-6725 Szeged, Hungary.
Ormándi K; Department of Radiology, Albert Szent-Györgyi Health Centre, University of Szeged, 6 Semmelweis Street, H-6725 Szeged, Hungary.
Pankotai T; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.; Competence Centre of the Life Sciences Cluster of the Centre of Excellence for Interdisciplinary Research, Development and Innovation, University of Szeged, Dugonics tér 13, H-6720 Szeged, Hungary.; Genome Integrity and DNA Repair Core Group, Hungarian Centre of Excellence for Molecular Medicine (HCEMM), University of Szeged, Budapesti út 9, H-6728 Szeged, Hungary.
Boros IM; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Villányi Z; Department of Biochemistry and Molecular Biology, University of Szeged, 52 Középfasor, H-6726 Szeged, Hungary.
Vörös A; Department of Pathology, Albert Szent-Györgyi Medical School, University of Szeged, Állomás utca 1, H-6725 Szeged, Hungary.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Nov 01; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 01.
Typ publikacji:
Journal Article
MeSH Terms:
RNA Polymerase II*/genetics
Saccharomyces cerevisiae Proteins*/metabolism
Humans ; Neoadjuvant Therapy ; Protein Aggregates ; Saccharomyces cerevisiae/metabolism
Czasopismo naukowe
Tytuł:
SINEs as Potential Expression Cassettes: Impact of Deletions and Insertions on Polyadenylation and Lifetime of B2 and Ves SINE Transcripts Generated by RNA Polymerase III.
Autorzy:
Borodulina OR; Laboratory of Eukaryotic Genome Evolution, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia.
Ustyantsev IG; Laboratory of Eukaryotic Genome Evolution, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia.
Kramerov DA; Laboratory of Eukaryotic Genome Evolution, Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow 119991, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Sep 27; Vol. 24 (19). Date of Electronic Publication: 2023 Sep 27.
Typ publikacji:
Journal Article
MeSH Terms:
Polyadenylation*/genetics
RNA Polymerase III*/genetics
Animals ; Humans ; HeLa Cells ; Short Interspersed Nucleotide Elements/genetics ; Promoter Regions, Genetic ; Mammals/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł:
Chromatin-transcription interface: The secret of eternal youth?
Autorzy:
Izquierdo JM; Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain.
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Źródło:
Aging cell [Aging Cell] 2023 Sep; Vol. 22 (9), pp. e13927. Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromatin*/genetics
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
Animals ; Adolescent ; Humans ; Aging/genetics ; Longevity/genetics ; Cell Line ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
Covalent Inhibitors from Saudi Medicinal Plants Target RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2.
Autorzy:
Bakheit AH; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Saquib Q; Zoology Department, College of Sciences, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Ahmed S; Department of Pharmacognosy, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Ansari SM; Botany & Microbiology Department, College of Sciences, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Al-Salem AM; Zoology Department, College of Sciences, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Al-Khedhairy AA; Zoology Department, College of Sciences, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
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Źródło:
Viruses [Viruses] 2023 Oct 30; Vol. 15 (11). Date of Electronic Publication: 2023 Oct 30.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Plants, Medicinal*/chemistry
RNA-Dependent RNA Polymerase*/antagonists & inhibitors
SARS-CoV-2*/drug effects
Amino Acids ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Saudi Arabia
Czasopismo naukowe
Tytuł:
Combined SPT and FCS methods reveal a mechanism of RNAP II oversampling in cell nuclei.
Autorzy:
Fournier M; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Leclerc P; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Leray A; Laboratoire Interdisciplinaire Carnot de Bourgogne, UMR 6303 CNRS, Université de Bourgogne Franche Comte, Dijon, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Champelovier D; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Agbazahou F; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Dahmani F; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Bidaux G; INSERM UMR 1060, CarMeN Laboratory, IHU OPERA, Hôpital Louis Pradel, Hospices Civils de Lyon, Univ Lyon1, Lyon, France.; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France.
Furlan A; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France. .; Univ. Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277 -CANTHER -Cancer Heterogeneity Plasticity and Resistance to Therapies, Lille, 59000, France. .; Unité Tumorigenèse et Résistance aux Traitements, Centre Oscar Lambret, 59000, Lille, France. .; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France. .
Héliot L; Univ. Lille, CNRS, UMR 8523, PhLAM Laboratoire de Physique des Lasers, Atomes et Molécules, Lille, France. .; CNRS, Groupement de Recherche ImaBio, 59655, Villeneuve d'Ascq, France. .
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Źródło:
Scientific reports [Sci Rep] 2023 Sep 05; Vol. 13 (1), pp. 14633. Date of Electronic Publication: 2023 Sep 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
RNA Polymerase II*
Single Molecule Imaging*
Cell Nucleus ; Transcription, Genetic ; Microscopy
Czasopismo naukowe
Tytuł:
Neuroimaging of POLR3B -related Hypomyelinating Leukodystrophy.
Autorzy:
M Borella LF; Department of Radiology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
Pereira DA; Department of Human Reproduction and Childhood, Pontifical Catholic University of São Paulo (PUC-SP), Sorocaba, SP, Brazil.
Reis F; Department of Radiology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
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Źródło:
Neurology India [Neurol India] 2023 Sep-Oct; Vol. 71 (5), pp. 1098-1099.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroimaging*
RNA Polymerase III*/genetics
Humans ; Mutation
Czasopismo naukowe
Tytuł:
Recurrent Implantation Failure: Bioinformatic Discovery of Biomarkers and Identification of Metabolic Subtypes.
Autorzy:
Fan Y; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.; Reproductive Medical Center, Peking University People's Hospital, Beijing 100044, China.
Shi C; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.; Reproductive Medical Center, Peking University People's Hospital, Beijing 100044, China.
Huang N; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.; Reproductive Medical Center, Peking University People's Hospital, Beijing 100044, China.
Fang F; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.; Reproductive Medical Center, Peking University People's Hospital, Beijing 100044, China.
Tian L; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.; Reproductive Medical Center, Peking University People's Hospital, Beijing 100044, China.
Wang J; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 30; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 30.
Typ publikacji:
Journal Article
MeSH Terms:
Computational Biology*
RNA Polymerase III*
Female ; Humans ; Biomarkers ; Area Under Curve ; Cluster Analysis ; Databases, Factual
Czasopismo naukowe
Tytuł:
nc886, an RNA Polymerase III-Transcribed Noncoding RNA Whose Expression Is Dynamic and Regulated by Intriguing Mechanisms.
Autorzy:
Lee YS; Rare Cancer Branch, Research Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Lee YS; Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang 10408, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 May 10; Vol. 24 (10). Date of Electronic Publication: 2023 May 10.
Typ publikacji:
Journal Article; Review
MeSH Terms:
RNA Polymerase III*/genetics
RNA Polymerase III*/metabolism
RNA, Untranslated*/genetics
RNA, Untranslated*/metabolism
Humans ; DNA Methylation ; Cell Transformation, Neoplastic/genetics ; Carcinogenesis/genetics ; Transcription, Genetic
Czasopismo naukowe
Tytuł:
HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter.
Autorzy:
Anastasopoulou S; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Georgakopoulos T; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
Mouzaki A; Laboratory of Immunohematology, Division of Hematology, Department of Internal Medicine, Medical School, University of Patras, GR-26500 Patras, Greece.
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Źródło:
Biomolecules [Biomolecules] 2023 May 24; Vol. 13 (6). Date of Electronic Publication: 2023 May 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
HIV Infections*/genetics
HIV Infections*/immunology
HIV Infections*/virology
HIV-1*/genetics
HIV-1*/metabolism
Interleukin-2*/genetics
Interleukin-2*/metabolism
RNA Polymerase II*/genetics
RNA Polymerase II*/metabolism
tat Gene Products, Human Immunodeficiency Virus*/genetics
tat Gene Products, Human Immunodeficiency Virus*/metabolism
Humans ; Gene Expression Regulation, Viral ; Transcription Factors/metabolism ; Transcription, Genetic ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
Structural Transition of the Nucleosome during Transcription Elongation.
Autorzy:
Kujirai T; Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.; Laboratory for Transcription Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.
Ehara H; Laboratory for Transcription Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.
Sekine SI; Laboratory for Transcription Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.
Kurumizaka H; Laboratory of Chromatin Structure and Function, Institute for Quantitative Biosciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan.; Laboratory for Transcription Structural Biology, RIKEN Center for Biosystems Dynamics Research, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.
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Źródło:
Cells [Cells] 2023 May 14; Vol. 12 (10). Date of Electronic Publication: 2023 May 14.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Nucleosomes*
RNA Polymerase II*/metabolism
Transcription, Genetic ; Chromatin/genetics ; DNA
Czasopismo naukowe

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