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Wyszukujesz frazę ""Rocha-Pereira J"" wg kryterium: Autor


Wyświetlanie 1-9 z 9
Tytuł :
Infection of zebrafish larvae with human norovirus and evaluation of the in vivo efficacy of small-molecule inhibitors.
Autorzy :
Van Dycke J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Cuvry A; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Knickmann J; University of Lübeck-Institute of Virology and Cell Biology, Lübeck, Germany.
Ny A; KU Leuven-Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Biodiscovery, Leuven, Belgium.
Rakers S; Fraunhofer Research Institution for Marine Biotechnology and Cell Technology EMB, WG Aquatic Cell Technology and Aquaculture, Lübeck, Germany.
Taube S; University of Lübeck-Institute of Virology and Cell Biology, Lübeck, Germany.
de Witte P; KU Leuven-Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Molecular Biodiscovery, Leuven, Belgium.
Neyts J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium.; Global Virus Network (GVN), Centers of Excellence, Baltimore, MD, USA.
Rocha-Pereira J; KU Leuven-Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory of Virology and Chemotherapy, Leuven, Belgium. .
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Źródło :
Nature protocols [Nat Protoc] 2021 Apr; Vol. 16 (4), pp. 1830-1849. Date of Electronic Publication: 2021 Apr 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caliciviridae Infections/*virology
Norovirus/*physiology
Small Molecule Libraries/*pharmacology
Zebrafish/*virology
Animals ; Embryo, Nonmammalian/virology ; Humans ; Immunity, Innate ; Larva/drug effects ; Larva/immunology ; Norovirus/genetics ; Reproducibility of Results ; Virus Replication ; Zebrafish/embryology
Czasopismo naukowe
Tytuł :
Interferon lambda (IFN-λ) efficiently blocks norovirus transmission in a mouse model.
Autorzy :
Rocha-Pereira J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Jacobs S; Université Catholique de Louvain (UCL), de Duve Institute, Brussels, Belgium.
Noppen S; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Verbeken E; KU Leuven - University of Leuven, Department of Imaging & Pathology, Translational Cell & Tissue Research, Leuven, Belgium.
Michiels T; Université Catholique de Louvain (UCL), de Duve Institute, Brussels, Belgium.
Neyts J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2018 Jan; Vol. 149, pp. 7-15. Date of Electronic Publication: 2017 Nov 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caliciviridae Infections/*genetics
Caliciviridae Infections/*transmission
Interferons/*genetics
Norovirus/*physiology
Animals ; Antibodies, Viral/immunology ; Caliciviridae Infections/mortality ; Caliciviridae Infections/virology ; Cell Line ; Disease Models, Animal ; Gene Expression ; Gene Expression Regulation ; Immunoglobulin G/immunology ; Interferon Regulatory Factors/genetics ; Interferon Regulatory Factors/metabolism ; Interferons/blood ; Interferons/metabolism ; Intestine, Small/metabolism ; Intestine, Small/pathology ; Intestine, Small/virology ; Mice ; Plasmids/genetics ; Virus Replication
Czasopismo naukowe
Tytuł :
Norovirus genetic diversity and evolution: implications for antiviral therapy.
Autorzy :
Rocha-Pereira J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Van Dycke J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Neyts J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium. Electronic address: .
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Źródło :
Current opinion in virology [Curr Opin Virol] 2016 Oct; Vol. 20, pp. 92-98. Date of Electronic Publication: 2016 Oct 11.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Variation*
Antiviral Agents/*pharmacology
Antiviral Agents/*therapeutic use
Caliciviridae Infections/*virology
Norovirus/*classification
Norovirus/*genetics
Drug Resistance, Viral ; Foodborne Diseases/virology ; Gastroenteritis/virology ; Humans ; Norovirus/drug effects
Czasopismo naukowe
Tytuł :
Inhibition of human norovirus by a viral polymerase inhibitor in the B cell culture system and in the mouse model.
Autorzy :
Kolawole AO; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Rocha-Pereira J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000, Leuven, Belgium.
Elftman MD; Department of Biomedical and Diagnostic Sciences, University of Detroit Mercy School of Dentistry, Detroit, MI, USA.
Neyts J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, B-3000, Leuven, Belgium.
Wobus CE; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2016 Aug; Vol. 132, pp. 46-9. Date of Electronic Publication: 2016 May 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
B-Lymphocytes/*drug effects
B-Lymphocytes/*virology
Caliciviridae Infections/*virology
Norovirus/*drug effects
Norovirus/*physiology
Animals ; Caliciviridae Infections/drug therapy ; Cell Line ; Disease Models, Animal ; Humans ; Mice ; Mice, Knockout ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Post-exposure antiviral treatment of norovirus infections effectively protects against diarrhea and reduces virus shedding in the stool in a mortality mouse model.
Autorzy :
Rocha-Pereira J; KU Leuven, University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Kolawole AO; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Verbeken E; KU Leuven - University of Leuven, Department of Imaging & Pathology, Translational Cell & Tissue Research, Leuven, Belgium.
Wobus CE; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA.
Neyts J; KU Leuven, University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium. Electronic address: .
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Źródło :
Antiviral research [Antiviral Res] 2016 Aug; Vol. 132, pp. 76-84. Date of Electronic Publication: 2016 May 29.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*pharmacology
Caliciviridae Infections/*virology
Diarrhea/*virology
Feces/*virology
Norovirus/*drug effects
Norovirus/*physiology
Virus Shedding/*drug effects
Animals ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Antibody Specificity/immunology ; Antigens, Viral ; Caliciviridae Infections/drug therapy ; Caliciviridae Infections/immunology ; Caliciviridae Infections/mortality ; Diarrhea/drug therapy ; Diarrhea/immunology ; Diarrhea/mortality ; Disease Models, Animal ; Fluid Therapy ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Mice ; Viral Load ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants.
Autorzy :
Rocha-Pereira J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Van Dycke J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium.
Neyts J; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Virology and Chemotherapy, Leuven, Belgium .
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Źródło :
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2015 Dec 28; Vol. 60 (3), pp. 1907-11. Date of Electronic Publication: 2015 Dec 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Caliciviridae Infections/*drug therapy
Cytidine/*analogs & derivatives
Gastroenteritis/*drug therapy
Norovirus/*drug effects
Virus Shedding/*drug effects
Amides/therapeutic use ; Animals ; Caliciviridae Infections/virology ; Cytidine/therapeutic use ; Disease Models, Animal ; Feces/virology ; Gastroenteritis/virology ; Mice ; Mice, Knockout ; Norovirus/growth & development ; Pyrazines/therapeutic use ; Receptors, Interferon/genetics ; Transplant Recipients
Czasopismo naukowe
Tytuł :
Prophylactic treatment with the nucleoside analogue 2'-C-methylcytidine completely prevents transmission of norovirus.
Autorzy :
Rocha-Pereira J; KU Leuven-University of Leuven, Rega Institute for Medical Research, Leuven, Belgium.
Jochmans D; KU Leuven-University of Leuven, Rega Institute for Medical Research, Leuven, Belgium.
Neyts J; KU Leuven-University of Leuven, Rega Institute for Medical Research, Leuven, Belgium .
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Źródło :
The Journal of antimicrobial chemotherapy [J Antimicrob Chemother] 2015 Jan; Vol. 70 (1), pp. 190-7. Date of Electronic Publication: 2014 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*therapeutic use
Caliciviridae Infections/*prevention & control
Chemoprevention/*methods
Cytidine/*analogs & derivatives
Norovirus/*drug effects
Animals ; Cytidine/therapeutic use ; Diarrhea/prevention & control ; Disease Models, Animal ; Female ; Male ; Mice ; Survival Analysis
Czasopismo naukowe
Tytuł :
Norovirus: targets and tools in antiviral drug discovery.
Autorzy :
Rocha-Pereira J; Rega Institute for Medical Research, KU Leuven - University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium.
Neyts J; Rega Institute for Medical Research, KU Leuven - University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium. Electronic address: .
Jochmans D; Rega Institute for Medical Research, KU Leuven - University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium.
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2014 Sep 01; Vol. 91 (1), pp. 1-11. Date of Electronic Publication: 2014 Jun 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Antiviral Agents/*pharmacology
Caliciviridae Infections/*drug therapy
Caliciviridae Infections/*transmission
Gastroenteritis/*epidemiology
Norovirus/*drug effects
Norovirus/*genetics
Norovirus/*pathogenicity
Animals ; Caliciviridae Infections/epidemiology ; Caliciviridae Infections/virology ; Cells, Cultured/virology ; Gastroenteritis/prevention & control ; Gastroenteritis/virology ; Genetic Variation ; Humans ; Mice ; Molecular Targeted Therapy ; Swine ; Viral Vaccines/immunology ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł :
The viral polymerase inhibitor 2'-C-methylcytidine inhibits Norwalk virus replication and protects against norovirus-induced diarrhea and mortality in a mouse model.
Autorzy :
Rocha-Pereira J; Laboratório de Microbiologia, Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal.
Jochmans D
Debing Y
Verbeken E
Nascimento MS
Neyts J
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Źródło :
Journal of virology [J Virol] 2013 Nov; Vol. 87 (21), pp. 11798-805. Date of Electronic Publication: 2013 Aug 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antiviral Agents/*therapeutic use
Caliciviridae Infections/*prevention & control
Cytidine/*analogs & derivatives
Diarrhea/*prevention & control
Norovirus/*drug effects
Norwalk virus/*drug effects
Virus Replication/*drug effects
Animal Structures/virology ; Animals ; Antiviral Agents/pharmacology ; Body Weight ; Caliciviridae Infections/mortality ; Caliciviridae Infections/pathology ; Cytidine/pharmacology ; Cytidine/therapeutic use ; Diarrhea/mortality ; Diarrhea/pathology ; Disease Models, Animal ; Feces/virology ; Female ; Male ; Mice ; Norwalk virus/physiology ; RNA, Viral/isolation & purification ; Survival Analysis ; Viral Load
Czasopismo naukowe
    Wyświetlanie 1-9 z 9

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