Targeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia.
Autorzy:
Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Kim SH; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. Kong M; Center for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, 02792, Korea. Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Yoon S; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Kee KM; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. Kim JA; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Kim DH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Kim H; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea. No KT; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.; Bioinformatics and Molecular Design Research Center (BMDRC), Incheon, 21983, Korea. Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Gee HY; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Hong S; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Lee H; Center for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, 02792, Korea. Kim DW; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. .; Hematology Department, Eulji Medical Center, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. . Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Nov 06; Vol. 22 (1), pp. 177. Date of Electronic Publication: 2023 Nov 06.
Correction: Reprogramming anchorage dependency by adherent‑to‑suspension transition promotes metastatic dissemination.
Autorzy:
Huh HD; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Sub Y; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea. Oh J; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea. Kim YE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Lee JY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Lee S; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea. Lee H; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Pak S; Cytogen, Seoul, Republic of Korea. Amos SE; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Vahala D; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Kim HS; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Brain Korea 21 Plus Project for Medical Sciences, Severance Biomedical Science Institute, Yonsei University College of Medicine, 03722, Seoul, Republic of Korea. Roh YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 03722, Seoul, Republic of Korea. Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, 92093, CA, USA. Choi YS; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Jeong J; Departments of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 06273, Seoul, Republic of Korea. Choi J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. . Gee HY; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea. . Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
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Molecular cancer [Mol Cancer] 2023 Aug 14; Vol. 22 (1), pp. 135. Date of Electronic Publication: 2023 Aug 14.
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination.
Autorzy:
Huh HD; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Sub Y; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Oh J; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Kim YE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Lee JY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Lee S; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Lee H; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Pak S; Cytogen, Seoul, Republic of Korea. Amos SE; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Vahala D; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Kim HS; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Brain Korea 21 Plus Project for Medical Sciences, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. Roh YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA. Choi YS; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia. Jeong J; Departments of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 06273, Republic of Korea. Choi J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. . Gee HY; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. . Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
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Molecular cancer [Mol Cancer] 2023 Mar 30; Vol. 22 (1), pp. 63. Date of Electronic Publication: 2023 Mar 30.
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment.
Autorzy:
Park HH; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea. Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, South Korea. Park SY; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea. Hwang SM; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea. Hong SM; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea. Park S; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.; Department of Physiology, Ajou University School of Medicine, Suwon, 16499, South Korea. Kang HC; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.; Department of Physiology, Ajou University School of Medicine, Suwon, 16499, South Korea. Morgan MJ; Department of Natural Sciences, Northeastern State University, Tahlequah, OK, 74464, USA. Cha JH; Department of Biomedical Sciences, College of Medicine, Inha University, Incheon, 22212, South Korea.; Department of Biomedical Science and Engineering, Graduate School, Inha University, Incheon, 22212, South Korea. Lee D; Department of Pathology, Ajou University School of Medicine, Suwon, 16499, South Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, South Korea. . Kim YS; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea. .; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2021 Aug 21; Vol. 20 (1), pp. 107. Date of Electronic Publication: 2021 Aug 21.
Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells.
Autorzy:
Lee HT; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea. Lee IH; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea. Kim JH; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea. Lee S; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea. Kwak S; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea. Suh MY; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea. Hwang IY; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea. Kang BG; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Korea. Cha SS; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Korea. Lee BI; Research Institute, National Cancer Center, Goyang-si 10408, Korea. Lee SE; Cardiology Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea. Choi J; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; College of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea. Cho EJ; College of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea. Youn HD; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2021 Jul 08; Vol. 13 (14). Date of Electronic Publication: 2021 Jul 08.
Epigenetic Upregulation of MAGE-A Isoforms Promotes Breast Cancer Cell Aggressiveness.
Autorzy:
Oh C; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea. Oh S; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.; Research Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea. Ko JY; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. Kim Y; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. Kang K; Department of Microbiology, College of Science & Technology, Dankook University, Cheonan 31116, Korea. Yang Y; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. Kim J; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. Park JH; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea. Yoo KH; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.; Research Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2021 Jun 25; Vol. 13 (13). Date of Electronic Publication: 2021 Jun 25.
Divergence of the PIERCE1 expression between mice and humans as a p53 target gene.
Autorzy:
Kim HJ; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. Lee SE; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. Na H; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. RoeJS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. Roh JI; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea. Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
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PloS one [PLoS One] 2020 Aug 03; Vol. 15 (8), pp. e0236881. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020).
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Autorzy:
Rathert P; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Roth M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Neumann T; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Muerdter F; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. RoeJS; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. Muhar M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Deswal S; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Cerny-Reiterer S; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria. Peter B; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria. Jude J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Hoffmann T; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Boryń ŁM; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Axelsson E; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Schweifer N; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria. Tontsch-Grunt U; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria. Dow LE; Department of Medicine, Hematology & Medical Oncology, Weill Cornell Medical College, New York 10065, USA. Gianni D; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria. Pearson M; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria. Valent P; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria. Stark A; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria. Kraut N; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria. Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA. Zuber J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
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Nature [Nature] 2015 Sep 24; Vol. 525 (7570), pp. 543-547. Date of Electronic Publication: 2015 Sep 14.
pVHL-mediated transcriptional repression of c-Myc by recruitment of histone deacetylases.
Autorzy:
Hwang IY; National Research Laboratory for Metabolic Checkpoint, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 110-799, Korea. RoeJS Seol JH Kim HR Cho EJ Youn HD
von Hippel-Lindau protein promotes Skp2 destabilization on DNA damage.
Autorzy:
RoeJS; National Research Laboratory for Metabolic Checkpoint, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Cancer Research Institute, Seoul National University College of Medicine, Republic of Korea. Kim HR Hwang IY Cho EJ Youn HD
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Źródło:
Oncogene [Oncogene] 2011 Jul 14; Vol. 30 (28), pp. 3127-38. Date of Electronic Publication: 2011 Feb 28.
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