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Wyświetlanie 1-11 z 11
Tytuł:
Targeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia.
Autorzy:
Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Kim SH; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea.
Kong M; Center for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, 02792, Korea.
Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Yoon S; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Kee KM; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea.
Kim JA; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Kim DH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Kim H; School of Life Sciences, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea.
No KT; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.; Bioinformatics and Molecular Design Research Center (BMDRC), Incheon, 21983, Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Gee HY; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Hong S; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Lee H; Center for Advanced Biomolecular Recognition, Korea Institute of Science and Technology, Seoul, 02792, Korea.
Kim DW; Leukemia Omics Research Institute, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. .; Hematology Department, Eulji Medical Center, Eulji University, Uijeongbu-si, Gyeonggi-Do, Republic of Korea. .
Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Nov 06; Vol. 22 (1), pp. 177. Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Blast Crisis*/drug therapy
Blast Crisis*/genetics
Blast Crisis*/pathology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/genetics
Animals ; Mice ; Humans ; Fusion Proteins, bcr-abl/genetics ; Drug Resistance, Neoplasm/genetics ; Signal Transduction ; Protein Kinase Inhibitors/pharmacology ; fms-Like Tyrosine Kinase 3/metabolism
Czasopismo naukowe
Tytuł:
Correction: Reprogramming anchorage dependency by adherent‑to‑suspension transition promotes metastatic dissemination.
Autorzy:
Huh HD; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Sub Y; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea.
Oh J; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea.
Kim YE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Lee JY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Lee S; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea.
Lee H; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Pak S; Cytogen, Seoul, Republic of Korea.
Amos SE; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Vahala D; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Kim HS; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Brain Korea 21 Plus Project for Medical Sciences, Severance Biomedical Science Institute, Yonsei University College of Medicine, 03722, Seoul, Republic of Korea.
Roh YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 03722, Seoul, Republic of Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, 92093, CA, USA.
Choi YS; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Jeong J; Departments of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, 06273, Seoul, Republic of Korea.
Choi J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
Gee HY; Department of Pharmacology, Graduate School of Medical Science, Yonsei University College of Medicine, Brain Korea 21, Project, Seoul, 03722, Republic of Korea. .
Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Aug 14; Vol. 22 (1), pp. 135. Date of Electronic Publication: 2023 Aug 14.
Typ publikacji:
Published Erratum
Tytuł:
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination.
Autorzy:
Huh HD; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Sub Y; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Oh J; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Kim YE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Lee JY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Lee S; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Lee H; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Pak S; Cytogen, Seoul, Republic of Korea.
Amos SE; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Vahala D; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Park JH; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Shin JE; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Park SY; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Kim HS; Yonsei Cancer Center, Division of Medical Oncology, Department of Internal Medicine, Brain Korea 21 Plus Project for Medical Sciences, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Roh YH; Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea.
Guan KL; Department of Pharmacology and Moores Cancer Center, University of California San Diego, La Jolla, CA, 92093, USA.
Choi YS; School of Human Sciences, University of Western Australia, Crawley, WA, 6009, Australia.
Jeong J; Departments of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, 06273, Republic of Korea.
Choi J; College of Pharmacy, Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
Gee HY; Department of Pharmacology, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea. .
Park HW; Department of Biochemistry, College of Life Science and Biotechnology, Brain Korea 21 Project, Yonsei University, Seoul, 03722, Republic of Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2023 Mar 30; Vol. 22 (1), pp. 63. Date of Electronic Publication: 2023 Mar 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplastic Cells, Circulating*/pathology
Breast Neoplasms*/genetics
Breast Neoplasms*/pathology
Melanoma*/metabolism
Lung Neoplasms*/pathology
Mice ; Animals ; Humans ; Female ; Cell Line, Tumor ; Neoplasm Metastasis
Czasopismo naukowe
Tytuł:
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment.
Autorzy:
Park HH; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.
Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, South Korea.
Park SY; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.
Hwang SM; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.
Hong SM; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea.
Park S; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.; Department of Physiology, Ajou University School of Medicine, Suwon, 16499, South Korea.
Kang HC; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea.; Department of Physiology, Ajou University School of Medicine, Suwon, 16499, South Korea.
Morgan MJ; Department of Natural Sciences, Northeastern State University, Tahlequah, OK, 74464, USA.
Cha JH; Department of Biomedical Sciences, College of Medicine, Inha University, Incheon, 22212, South Korea.; Department of Biomedical Science and Engineering, Graduate School, Inha University, Incheon, 22212, South Korea.
Lee D; Department of Pathology, Ajou University School of Medicine, Suwon, 16499, South Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, 03722, South Korea. .
Kim YS; Department of Biochemistry, Ajou University School of Medicine, Suwon, 16499, South Korea. .; Department of Biomedical Sciences, Graduate School, Ajou University, Suwon, 16499, South Korea. .
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Źródło:
Molecular cancer [Mol Cancer] 2021 Aug 21; Vol. 20 (1), pp. 107. Date of Electronic Publication: 2021 Aug 21.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Receptor-Interacting Protein Serine-Threonine Kinases/*metabolism
Tripartite Motif-Containing Protein 28/*genetics
Tumor Microenvironment/*genetics
Animals ; Binding Sites ; Cell Death ; Cell Line ; Cytokines/metabolism ; Humans ; Mice ; Models, Biological ; NF-kappa B/metabolism ; Necroptosis ; Neoplasms/genetics ; Neoplasms/metabolism ; Protein Binding ; Signal Transduction
Czasopismo naukowe
Tytuł:
Phosphorylation of OGFOD1 by Cell Cycle-Dependent Kinase 7/9 Enhances the Transcriptional Activity of RNA Polymerase II in Breast Cancer Cells.
Autorzy:
Lee HT; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.
Lee IH; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Kim JH; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Lee S; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Molecular Medicine & Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 03080, Korea.
Kwak S; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Suh MY; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Hwang IY; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
Kang BG; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Korea.
Cha SS; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Korea.
Lee BI; Research Institute, National Cancer Center, Goyang-si 10408, Korea.
Lee SE; Cardiology Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.
Choi J; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; College of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Cho EJ; College of Pharmacy, Sungkyunkwan University, Suwon 16419, Korea.
Youn HD; National Creative Research Center for Epigenome Reprogramming Network, Department of Biomedical Sciences, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul 03080, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2021 Jul 08; Vol. 13 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Epigenetic Upregulation of MAGE-A Isoforms Promotes Breast Cancer Cell Aggressiveness.
Autorzy:
Oh C; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Kim HR; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Oh S; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.; Research Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea.
Ko JY; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Kim Y; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Kang K; Department of Microbiology, College of Science & Technology, Dankook University, Cheonan 31116, Korea.
Yang Y; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Kim J; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Park JH; Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Korea.
Yoo KH; Laboratory of Biomedical Genomics, Department of Biological Sciences, Sookmyung Women's University, Seoul 04310, Korea.; Research Institute of Women's Health, Sookmyung Women's University, Seoul 04310, Korea.
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Źródło:
Cancers [Cancers (Basel)] 2021 Jun 25; Vol. 13 (13). Date of Electronic Publication: 2021 Jun 25.
Typ publikacji:
Journal Article
Czasopismo naukowe
Tytuł:
Divergence of the PIERCE1 expression between mice and humans as a p53 target gene.
Autorzy:
Kim HJ; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee SE; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Na H; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Roe JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Roh JI; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
Lee HW; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul, Republic of Korea.
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Źródło:
PloS one [PLoS One] 2020 Aug 03; Vol. 15 (8), pp. e0236881. Date of Electronic Publication: 2020 Aug 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Cycle Proteins*/genetics
Cell Cycle Proteins*/metabolism
Response Elements/*genetics
Tumor Suppressor Protein p53/*metabolism
Animals ; Cell Cycle/genetics ; Cell Line, Tumor ; DNA Damage/genetics ; Humans ; Mice ; Promoter Regions, Genetic ; Transcription, Genetic/physiology
Czasopismo naukowe
Tytuł:
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Autorzy:
Rathert P; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Roth M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Neumann T; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Muerdter F; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Roe JS; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Muhar M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Deswal S; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Cerny-Reiterer S; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria.
Peter B; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria.
Jude J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Hoffmann T; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Boryń ŁM; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Axelsson E; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Schweifer N; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria.
Tontsch-Grunt U; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria.
Dow LE; Department of Medicine, Hematology & Medical Oncology, Weill Cornell Medical College, New York 10065, USA.
Gianni D; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria.
Pearson M; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria.
Valent P; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria.; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, 1090 Vienna, Austria.
Stark A; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
Kraut N; Boehringer Ingelheim - Regional Center Vienna GmbH, 1121 Vienna, Austria.
Vakoc CR; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.
Zuber J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.
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Źródło:
Nature [Nature] 2015 Sep 24; Vol. 525 (7570), pp. 543-547. Date of Electronic Publication: 2015 Sep 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Azepines/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Drug Resistance, Neoplasm/*genetics
Gene Expression Regulation, Neoplastic/*drug effects
Leukemia, Myeloid, Acute/*genetics
Nuclear Proteins/*antagonists & inhibitors
Transcription Factors/*antagonists & inhibitors
Transcription, Genetic/*drug effects
Triazoles/*pharmacology
Animals ; Cell Cycle Proteins ; Cell Line, Tumor ; Chromatin/genetics ; Chromatin/metabolism ; Enhancer Elements, Genetic/genetics ; Female ; Gene Expression Regulation, Neoplastic/genetics ; Genes, myc/genetics ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/metabolism ; Leukemia, Myeloid, Acute/pathology ; Male ; Mice ; Nuclear Proteins/metabolism ; Transcription Factors/metabolism ; Transcription, Genetic/genetics ; Wnt Signaling Pathway/drug effects
Czasopismo naukowe
Tytuł:
pVHL-mediated transcriptional repression of c-Myc by recruitment of histone deacetylases.
Autorzy:
Hwang IY; National Research Laboratory for Metabolic Checkpoint, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 110-799, Korea.
Roe JS
Seol JH
Kim HR
Cho EJ
Youn HD
Pokaż więcej
Źródło:
Molecules and cells [Mol Cells] 2012 Feb; Vol. 33 (2), pp. 195-201.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Expression Regulation, Neoplastic*
Carcinoma, Renal Cell/*genetics
Histone Deacetylases/*metabolism
Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism
Kidney Neoplasms/*genetics
Proto-Oncogene Proteins c-myc/*genetics
Von Hippel-Lindau Tumor Suppressor Protein/*metabolism
Acetylation ; Carcinoma, Renal Cell/enzymology ; Cell Proliferation ; HEK293 Cells ; Homeostasis ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Kidney Neoplasms/enzymology ; Promoter Regions, Genetic/genetics ; Protein Binding ; Response Elements/genetics ; Sequence Deletion/genetics ; Transcriptional Activation/genetics ; Von Hippel-Lindau Tumor Suppressor Protein/genetics
Czasopismo naukowe
Tytuł:
von Hippel-Lindau protein promotes Skp2 destabilization on DNA damage.
Autorzy:
Roe JS; National Research Laboratory for Metabolic Checkpoint, Departments of Biomedical Sciences and Biochemistry and Molecular Biology, Cancer Research Institute, Seoul National University College of Medicine, Republic of Korea.
Kim HR
Hwang IY
Cho EJ
Youn HD
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2011 Jul 14; Vol. 30 (28), pp. 3127-38. Date of Electronic Publication: 2011 Feb 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
DNA Damage*
S-Phase Kinase-Associated Proteins/*chemistry
S-Phase Kinase-Associated Proteins/*metabolism
Von Hippel-Lindau Tumor Suppressor Protein/*metabolism
Apoptosis ; Carcinoma, Renal Cell/pathology ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Gene Expression Regulation, Neoplastic ; HCT116 Cells ; HEK293 Cells ; Humans ; Kidney Neoplasms/pathology ; Kinetics ; Phosphorylation ; Protein Stability ; Proto-Oncogene Proteins c-akt/metabolism ; S Phase ; Ubiquitination
Czasopismo naukowe
    Wyświetlanie 1-11 z 11

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