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    Tytuł:
    Glycogen synthase kinase 3-β inhibition induces lymphangiogenesis through β-catenin-dependent and mTOR-independent pathways.
    Autorzy:
    Stump B; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Shrestha S; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Lamattina AM; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Louis PH; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Cho W; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Perrella MA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Ai X; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Wagner FF; Stanley Center for Psychiatric Research, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America.
    Priolo C; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Astin J; Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand.
    El-Chemaly S; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2019 Apr 09; Vol. 14 (4), pp. e0213831. Date of Electronic Publication: 2019 Apr 09 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Lymphangiogenesis/*physiology
    beta Catenin/*metabolism
    Cell Culture Techniques ; Cell Line ; Endothelial Cells/physiology ; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors ; Glycogen Synthase Kinase 3 beta/genetics ; Humans ; Indoles/pharmacology ; Lung/cytology ; Lymphangiogenesis/drug effects ; Lymphatic Vessels/cytology ; Maleimides/pharmacology ; Microvessels/cytology ; Phosphorylation ; Protein Stability ; RNA, Small Interfering/metabolism ; Signal Transduction/drug effects ; Signal Transduction/physiology ; TOR Serine-Threonine Kinases/metabolism ; beta Catenin/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Clinical management and outcomes of patients with Hermansky-Pudlak syndrome pulmonary fibrosis evaluated for lung transplantation.
    Autorzy:
    El-Chemaly S; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    O'Brien KJ; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
    Nathan SD; Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls Church, Virginia, United States of America.
    Weinhouse GL; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Goldberg HJ; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Connors JM; Division of Hematology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Cui Y; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Astor TL; Division of Pulmonary & Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
    Camp PC Jr; Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Lemma M; Advanced Lung Disease and Transplant Program, Inova Fairfax Hospital, Falls Church, Virginia, United States of America.
    Speransky V; National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, United States of America.
    Merideth MA; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
    Gahl WA; Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
    Gochuico BR; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
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    Źródło:
    PloS one [PLoS One] 2018 Mar 16; Vol. 13 (3), pp. e0194193. Date of Electronic Publication: 2018 Mar 16 (Print Publication: 2018).
    Typ publikacji:
    Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hermanski-Pudlak Syndrome*/blood
    Hermanski-Pudlak Syndrome*/mortality
    Hermanski-Pudlak Syndrome*/physiopathology
    Hermanski-Pudlak Syndrome*/surgery
    Lung Transplantation*
    Adult ; Female ; Humans ; Male ; Middle Aged ; Pulmonary Fibrosis/blood ; Pulmonary Fibrosis/mortality ; Pulmonary Fibrosis/physiopathology ; Pulmonary Fibrosis/surgery
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Association of Donor and Recipient Telomere Length with Clinical Outcomes following Lung Transplantation.
    Autorzy:
    Courtwright AM; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Fried S; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Villalba JA; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Moniodis A; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Guleria I; Tissue Typing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Wood I; Tissue Typing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Milford E; Tissue Typing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Mallidi HH; Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Hunninghake GM; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Raby BA; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Agarwal S; Division of Hematology/Oncology, Boston Children's Hospital, Boston, Massachusetts, United States of America.
    Camp PC; Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Goldberg HJ; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    El-Chemaly S; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2016 Sep 02; Vol. 11 (9), pp. e0162409. Date of Electronic Publication: 2016 Sep 02 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Observational Study
    MeSH Terms:
    Lung Transplantation*
    Telomere*
    Tissue Donors*
    Transplant Recipients*
    Treatment Outcome*
    Adult ; Aged ; Female ; Graft Rejection/genetics ; Humans ; Male ; Middle Aged ; Prognosis ; Telomere Shortening/genetics ; Young Adult
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis.
    Autorzy:
    Patel AS; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
    Song JW; Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, South Korea.
    Chu SG; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
    Mizumura K; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.
    Osorio JC; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
    Shi Y; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
    El-Chemaly S; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
    Lee CG; Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Elias JA; Alpert Medical School, Brown University, Providence, Rhode Island, United States of America.
    Choi AM; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.
    Morse D; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2015 Mar 18; Vol. 10 (3), pp. e0121246. Date of Electronic Publication: 2015 Mar 18 (Print Publication: 2015).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Epithelial Cells/*pathology
    Mitochondria/*drug effects
    Protein Kinases/*metabolism
    Pulmonary Fibrosis/*enzymology
    Pulmonary Fibrosis/*pathology
    Transforming Growth Factor beta1/*pharmacology
    Animals ; Bleomycin/adverse effects ; Cell Death/drug effects ; Cell Line ; Epithelial Cells/drug effects ; Gene Expression Regulation, Enzymologic/drug effects ; Humans ; Male ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/pathology ; Mitophagy/drug effects ; Pulmonary Alveoli/pathology ; Pulmonary Fibrosis/chemically induced ; Reactive Oxygen Species/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Rapamycin-insensitive up-regulation of adipocyte phospholipase A2 in tuberous sclerosis and lymphangioleiomyomatosis.
    Autorzy:
    Li C; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Zhang E; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Sun Y; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Lee PS; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Zhan Y; Peking Union Medical College, Beijing, China.
    Guo Y; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Osorio JC; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Rosas IO; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Xu KF; Peking Union Medical College, Beijing, China.
    Kwiatkowski DJ; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
    Yu JJ; Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 Oct 27; Vol. 9 (10), pp. e104809. Date of Electronic Publication: 2014 Oct 27 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
    MeSH Terms:
    Adipocytes/*drug effects
    Adipocytes/*metabolism
    Gene Expression Regulation/*drug effects
    Lymphangioleiomyomatosis/*genetics
    Phospholipases A2/*genetics
    Sirolimus/*pharmacology
    Tuberous Sclerosis/*genetics
    Angiomyolipoma/genetics ; Angiomyolipoma/metabolism ; Animals ; Cell Line ; Cluster Analysis ; Disease Models, Animal ; Enzyme Activation/drug effects ; Female ; Gene Expression Profiling ; Gene Knockout Techniques ; Humans ; Lung/metabolism ; Lung/pathology ; Lymphangioleiomyomatosis/metabolism ; Mice ; Tuberous Sclerosis/metabolism ; Tuberous Sclerosis Complex 2 Protein ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism ; Up-Regulation
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis.
    Autorzy:
    Craig VJ; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Polverino F; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Laucho-Contreras ME; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Shi Y; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Liu Y; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Osorio JC; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Tesfaigzi Y; Chronic Obstructive Pulmonary Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Pinto-Plata V; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Gochuico BR; Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
    Owen CA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Pulmonary Fibrosis Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America; Chronic Obstructive Pulmonary Disease Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico, United States of America.
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    Źródło:
    PloS one [PLoS One] 2014 May 14; Vol. 9 (5), pp. e97485. Date of Electronic Publication: 2014 May 14 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Epithelial Cells/*metabolism
    Idiopathic Pulmonary Fibrosis/*metabolism
    Lung/*metabolism
    Matrix Metalloproteinase 8/*metabolism
    Mononuclear Phagocyte System/*metabolism
    Aged ; Bronchoalveolar Lavage Fluid/chemistry ; Female ; Humans ; Leukocytes/metabolism ; Macrophages, Alveolar/metabolism ; Male ; Matrix Metalloproteinase 8/blood ; Middle Aged
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation.
    Autorzy:
    Nakahira K; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.
    Kyung SY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Internal Medicine, Gachon University Gil Hospital, Incheon, South Korea.
    Rogers AJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, California, United States of America.
    Gazourian L; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Youn S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Massaro AF; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Quintana C; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Osorio JC; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Wang Z; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America.
    Zhao Y; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America.
    Lawler LA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Christie JD; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Meyer NJ; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.
    Mc Causland FR; Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Waikar SS; Renal Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Waxman AB; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Chung RT; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Bueno R; Division of Thoracic Surgery, Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
    Rosas IO; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Fredenburgh LE; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Baron RM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Christiani DC; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America ; Pulmonary and Critical Care Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Hunninghake GM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.
    Choi AM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America ; Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America ; Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
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    Źródło:
    PLoS medicine [PLoS Med] 2013 Dec; Vol. 10 (12), pp. e1001577; discussion e1001577. Date of Electronic Publication: 2013 Dec 31.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Hospital Mortality*
    Biomarkers/*blood
    DNA, Mitochondrial/*blood
    Intensive Care Units/*statistics & numerical data
    Aged ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis.
    Autorzy:
    Xue J; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Gochuico BR
    Alawad AS
    Feghali-Bostwick CA
    Noth I
    Nathan SD
    Rosen GD
    Rosas IO
    Dacic S
    Ocak I
    Fuhrman CR
    Cuenco KT
    Smith MA
    Jacobs SS
    Zeevi A
    Morel PA
    Pilewski JM
    Valentine VG
    Gibson KF
    Kaminski N
    Sciurba FC
    Zhang Y
    Duncan SR
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    Źródło:
    PloS one [PLoS One] 2011 Feb 23; Vol. 6 (2), pp. e14715. Date of Electronic Publication: 2011 Feb 23.
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
    MeSH Terms:
    HLA-DR Antigens/*genetics
    Idiopathic Pulmonary Fibrosis/*genetics
    Aged ; Alleles ; Case-Control Studies ; Cohort Studies ; Female ; Gene Frequency ; Genetic Linkage ; Genetic Predisposition to Disease ; HLA-DRB1 Chains ; Histocompatibility Antigens Class II/genetics ; Humans ; Idiopathic Pulmonary Fibrosis/epidemiology ; Male ; Middle Aged ; Prevalence
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.
    Autorzy:
    Rosas IO; Dorothy P. and Richard P. Simmons Center for Interstitial Lung Diseases, Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh School ofMedicine, Pittsburgh, Pennsylvania, United States of America.
    Richards TJ
    Konishi K
    Zhang Y
    Gibson K
    Lokshin AE
    Lindell KO
    Cisneros J
    Macdonald SD
    Pardo A
    Sciurba F
    Dauber J
    Selman M
    Gochuico BR
    Kaminski N
    Pokaż więcej
    Źródło:
    PLoS medicine [PLoS Med] 2008 Apr 29; Vol. 5 (4), pp. e93.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Biomarkers/*blood
    Matrix Metalloproteinase 1/*blood
    Matrix Metalloproteinase 7/*blood
    Pulmonary Fibrosis/*diagnosis
    Adult ; Aged ; Bronchoalveolar Lavage Fluid/chemistry ; Clinical Enzyme Tests ; Cohort Studies ; Female ; Humans ; Lung/metabolism ; Male ; Middle Aged ; Oligonucleotide Array Sequence Analysis ; Pulmonary Fibrosis/blood
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-10 z 10

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