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Wyświetlanie 1-20 z 36
Tytuł:
Employing CRISPR-Cas9 to Generate CD133 Synthetic Lethal Melanoma Stem Cells.
Autorzy:
Simbulan-Rosenthal CM; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Haribabu Y; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Vakili S; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Kuo LW; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Clark H; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Dougherty R; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Alobaidi R; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
Carney B; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.; Firefighters' Burn and Surgical Laboratory, MedStar Health Research Institute, Washington, DC 20010, USA.
Sykora P; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.; Amelia Technologies, LLC, 1121 5th St. NW, Washington, DC 20001, USA.
Rosenthal DS; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University School of Medicine, Washington, DC 20057, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 20; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 20.
Typ publikacji:
Journal Article
MeSH Terms:
Melanoma*/drug therapy
Melanoma*/genetics
Melanoma*/pathology
Proto-Oncogene Proteins c-akt*/metabolism
Apoptosis/genetics ; CRISPR-Cas Systems/genetics ; Caspases/metabolism ; Cell Line, Tumor ; Humans ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Small Interfering/pharmacology ; Skin Neoplasms ; Stem Cells/metabolism ; bcl-2-Associated X Protein/metabolism ; Melanoma, Cutaneous Malignant
Czasopismo naukowe
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Tytuł:
Hypopigmented burn hypertrophic scar contains melanocytes that can be signaled to re-pigment by synthetic alpha-melanocyte stimulating hormone in vitro.
Autorzy:
Carney BC; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, United States of America.; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States of America.
Travis TE; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States of America.; Department of Surgery, The Burn Center, MedStar Washington Hospital Center, Washington, DC, United States of America.
Moffatt LT; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, United States of America.; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States of America.
Johnson LS; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States of America.; Department of Surgery, The Burn Center, MedStar Washington Hospital Center, Washington, DC, United States of America.
McLawhorn MM; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.
Simbulan-Rosenthal CM; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, United States of America.
Rosenthal DS; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, United States of America.
Shupp JW; Department of Biochemistry and Molecular and Cellular Biology, Georgetown University School of Medicine, Washington, DC, United States of America.; Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC, United States of America.; Department of Surgery, Georgetown University School of Medicine, Washington, DC, United States of America.; Department of Surgery, The Burn Center, MedStar Washington Hospital Center, Washington, DC, United States of America.
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Źródło:
PloS one [PLoS One] 2021 Mar 25; Vol. 16 (3), pp. e0248985. Date of Electronic Publication: 2021 Mar 25 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Burns/*pathology
Cicatrix, Hypertrophic/*pathology
Hypopigmentation/*pathology
Melanocytes/*pathology
alpha-MSH/*metabolism
Adult ; Animals ; Biopsy ; Biosynthetic Pathways ; Burns/complications ; Burns/genetics ; Cells, Cultured ; Cicatrix, Hypertrophic/complications ; Cicatrix, Hypertrophic/genetics ; Humans ; Hyperpigmentation/complications ; Hyperpigmentation/pathology ; Hypopigmentation/complications ; Hypopigmentation/genetics ; Male ; Melanins/biosynthesis ; Melanocytes/metabolism ; Middle Aged ; Phenotype ; Pigmentation ; Swine ; Up-Regulation/genetics ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Wyświetlanie 1-20 z 36

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