Autor: "Roudkenar MH" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Chrysin as an Anti-Cancer Agent Exerts Selective Toxicity by Directly Inhibiting Mitochondrial Complex II and V in CLL B-lymphocytes.
Autorzy:: Salimi A; a Faculty of Pharmacy, Department of Pharmacology and Toxicology , Shahid Beheshti University of Medical Sciences , Tehran , Iran.; b Department of Pharmacology and Toxicology , School of Pharmacy, Ardabil University of Medical Science , Ardabil , Iran.; c Students Research Committee, School of Pharmacy , Shahid Beheshti University of Medical Sciences , Tehran , Iran.
Roudkenar MH; d Biotechnology Research Center, Paramedicine Faculty , Guilan University of Medical Science , Rasht , Iran.
Seydi E; a Faculty of Pharmacy, Department of Pharmacology and Toxicology , Shahid Beheshti University of Medical Sciences , Tehran , Iran.
Sadeghi L; e Emam Hosein Educational Hospital Shahid Beheshti University of Medical Sciences , Tehran , Iran.
Mohseni A; f Faculty of Paramedicine, Department of Laboratory Sciences , Mazandaran University of Medical Sciences , Sari , Iran.
Pirahmadi N; a Faculty of Pharmacy, Department of Pharmacology and Toxicology , Shahid Beheshti University of Medical Sciences , Tehran , Iran.
Pourahmad J; a Faculty of Pharmacy, Department of Pharmacology and Toxicology , Shahid Beheshti University of Medical Sciences , Tehran , Iran.; Pokaż więcej
Źródło:: Cancer investigation [Cancer Invest] 2017 Mar 16; Vol. 35 (3), pp. 174-186. Date of Electronic Publication: 2017 Feb 17.
Typ publikacji:: Journal Article
MeSH Terms:: Adenosine Triphosphatases/*antagonists & inhibitors
Antineoplastic Agents/*pharmacology
B-Lymphocytes/*physiology
Carrier Proteins/*antagonists & inhibitors
Electron Transport Complex II/*antagonists & inhibitors
Flavonoids/*pharmacology
Leukemia, Lymphocytic, Chronic, B-Cell/*drug therapy
Membrane Proteins/*antagonists & inhibitors
Adenosine Diphosphate/metabolism ; Adenosine Triphosphate/metabolism ; Apoptosis/drug effects ; B-Lymphocytes/drug effects ; Caspase 3/metabolism ; Cell Survival/drug effects ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Humans ; Inhibitory Concentration 50 ; Membrane Potential, Mitochondrial/drug effects ; Mitochondrial Proton-Translocating ATPases ; Mitochondrial Swelling/drug effects ; Oxidative Phosphorylation ; Reactive Oxygen Species/metabolism ; Tumor Cells, Cultured