Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma.
Autorzy:
Lin SH; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Sampson JN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Ludwig Maximilians Universität (LMU), Munich, Germany.; Division of Translational Pediatric Sarcoma Research, German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.; Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. Surdez D; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France. Reynaud S; SIREDO Oncology Centre, Institut Curie, Paris, France. Mirabeau O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France. Karlins E; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. RubioRA; Max-Eder Research Group for Pediatric Sarcoma Biology, Ludwig Maximilians Universität (LMU), Munich, Germany. Zaidi S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France. Grossetête-Lalami S; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France. Ballet S; SIREDO Oncology Centre, Institut Curie, Paris, France. Lapouble E; SIREDO Oncology Centre, Institut Curie, Paris, France. Laurence V; SIREDO Oncology Centre, Institut Curie, Paris, France. Michon J; SIREDO Oncology Centre, Institut Curie, Paris, France. Pierron G; SIREDO Oncology Centre, Institut Curie, Paris, France. Kovar H; Children's Cancer Research Institute, St. Anna Kinderkrebsforschung, Vienna, Austria. Kontny U; Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Uniklinik RWTH Aachen, Aachen, Germany. González-Neira A; Human Genotyping Unit-CeGen, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Madrid, Spain. Alonso J; Unidad de Tumores Solidos Infantiles (IIER-ISCIII) & Centro de Investigación Biomédica en Red de Enfermedades Raras (CB06/07/1009; CIBERER-ISCIII), Instituto de Salud Carlos III, Majadahonda, Spain. Patino-Garcia A; Laboratory of Pediatrics, University Clinic of Navarra, Program in Solid Tumors, Center for Applied Medical Research (CIMA) and Navarra's Health Research Institute (IdiSNA), Pamplona, Spain. Corradini N; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, Lyon, France. Bérard PM; Institute for Paediatric Haematology and Oncology, Leon Bérard Cancer Centre, University of Lyon, Lyon, France. Miller J; Information Management Services, Inc., Calverton, MD, United States of America. Freedman ND; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Rothman N; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Carter BD; Behavioral and Epidemiology Research Group, American Cancer Society, Atlanta, GA, United States of America. Dagnall CL; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Burdett L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Jones K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Manning M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Wyatt K; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Zhou W; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Yeager M; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.; Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc., Frederick, MD, United States of America. Cox DG; Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France. Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Khan J; Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, United States of America. Armstrong GT; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States of America. Leisenring WM; Cancer Prevention and Clinical Statistics Programs, Fred Hutchinson Cancer Research Center, Seattle, WA, United States of America. Bhatia S; Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL, United States of America. Robison LL; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, United States of America. Kulozik AE; Department of Pediatric Oncology, Hematology and Immunology and Hopp Children Cancer Center, University of Heidelberg, Heidelberg, Germany. Kriebel J; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), München, Neuherberg, Germany. Meitinger T; German Research Center for Environmental Health, Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany. Metzler M; Department of Paediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany. Krumbholz M; Department of Paediatrics and Adolescent Medicine, University Hospital of Erlangen, Erlangen, Germany. Hartmann W; Division of Translational Pathology, Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany. Strauch K; Institute of Genetic Epidemiology, LMU Munich, Munich, Germany. Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. Dirksen U; Pediatrics III, West German Cancer Centre, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), Center Essen, Heidelberg, Germany. Mirabello L; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Tucker MA; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Tirode F; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France. Morton LM; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America. Delattre O; Inserm U830, Équipe Labellisés LNCC, PSL Université, Institut Curie, Paris, France.; SIREDO Oncology Centre, Institut Curie, Paris, France. Machiela MJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, United States of America.
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Źródło:
PloS one [PLoS One] 2020 Sep 03; Vol. 15 (9), pp. e0237792. Date of Electronic Publication: 2020 Sep 03 (Print Publication: 2020).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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