- Tytuł:
- Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
- Autorzy:
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Wheeler E; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.
Leong A; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.
Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Hivert MF; Department of Population Medicine, Harvard Medical School, Harvard Pilgrim Health Care Institute, Boston, MA, United States of America.; Massachusetts General Hospital, Boston, MA, United States of America.
Strawbridge RJ; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Podmore C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
Li M; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of Nephrology, University of Utah, Salt Lake City, UT, United States of America.; Department of Human Genetics, University of Utah, Salt Lake City, UT, United States of America.
Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Sim X; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Hong J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.
Chu AY; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Zhang W; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Wang X; Life Sciences Institute, National University of Singapore, Singapore, Singapore.
Chen P; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, United States of America.; Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, Jilin, China.; College of Basic Medical Sciences, Jilin University, Changchun, Jilin, China.
Maruthur NM; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Porneala BC; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.
Sharp SJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Jia Y; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Kabagambe EK; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chen WM; University of Virginia Center for Public Health Genomics, Charlottesville, VA, United States of America.
Elks CE; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.; Personalised Healthcare & Biomarkers, Innovative Medicines and Early Development Biotech Unit, AstraZeneca, Cambridge, United Kingdom.
Evans DS; California Pacific Medical Center Research Institute, San Francisco, CA, United States of America.
Fan Q; Centre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Go MJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Hottenga JJ; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Hu Y; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.
Kim YJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Ladenvall C; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Lecoeur C; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Lim SH; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.
Marzi C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Nalls MA; Data Tecnica International, Glen Echo, MD, United States of America.; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, United States of America.
Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.
Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Rybin DV; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; Data Coordinating Center, Boston University School of Public Health, Boston, MA, United States of America.
Sanna S; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Shi Y; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Stram DO; Department of Preventive Medicine, University of Southern California, Los Angeles, CA, United States of America.
Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Tan SP; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Van Vliet-Ostaptchouk JV; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong A; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Yengo L; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Zhao W; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Goel A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Martinez Larrad MT; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Radke D; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.
Salo P; National Institute for Health and Welfare (THL), Helsinki, Finland.; University of Helsinki, Institute for Molecular Medicine, Finland (FIMM) and Diabetes and Obesity Research Program, Helsinki, Finland.
Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, United States of America.
van Iperen EPA; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, Netherlands.
Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Afaq S; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Bertoni AG; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.
Bonnefond A; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Böttcher Y; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Carlson OD; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Cho YS; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.; Department of Biomedical Science, Hallym University, Chuncheon, Gangwon-do, South Korea.
Garvey WT; Department of Nutrition Sciences, University of Alabama at Birmingham and the Birmingham Veterans Affairs Medical Center, Birmingham, AL, United States of America.
Gieger C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Goodarzi MO; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, United States of America.
Grallert H; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Partner Munich, Munich, Germany.
Hamsten A; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.
Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Hsiung CA; Division of Endocrinology, Diabetes, Metabolism, Department of Internal Medicine, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Huang J; Boston VA Research Institute, Inc., Boston, MA, United States of America.
Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan.
Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Kiess W; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kohara K; Faculty of Collaborative Regional Innovation, Ehime University, Ehime, Japan.
Kovacs P; Integrated Research and Treatment (IFB) Center Adiposity Diseases, University of Leipzig, Leipzig, Germany.
Lee J; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Lehne B; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.
Li H; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu J; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.
Lobbens S; University of Lille, CNRS, Institut Pasteur of Lille, UMR 8199-EGID, Lille, France.
Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Lyssenko V; Lund University Diabetes Centre, Lund University, Lund, Sweden.
Meitinger T; Institute of Human Genetics, Technische Universität München, Munich, Germany.; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.
Miki T; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
MiljkovicI ; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.
Moon S; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Mulas A; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.
Müller G; Center for Evidence-based Healthcare, University Hospital and Medical Faculty Carl Gustav Carus, Dresden, Germany.
Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of MedicineI , University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
Nagaraja R; Laboratory of Genetics, National Institute on Aging, Baltimore, MD, United States of America.
Nauck M; Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany.
Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Polasek O; University of Split, Split, Croatia.; Centre for Population Health Sciences, University of Edinburgh, Edinburgh, United Kingdom.
ProkopenkoI ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.
Ramos PS; Department of Medicine, Medical University of South Carolina, Charleston, SC, United States of America.
Rasmussen-Torvik L; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Rathmann W; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Robertson NR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Department of Endocrinology and Diabetology, University Hospital Düsseldorf, Düsseldorf, Germany.
Roussel R; INSERM, UMR_S 1138, Centre de Recherche des Cordelier, Paris, France.; Université Paris Diderot, Sorbonne Paris Cité, UFR de Médecine, Paris, France.; Assistance Publique Hôpitaux de Paris, Bichat Hospital, DHU FIRE, Department of Diabetology, Endocrinology and Nutrition, Paris, France.Rudan I ; University of Edinburgh, Edinburgh, United Kingdom.
Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Scott WR; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.
Sennblad B; Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Centre for Molecular Medicine, Karolinska Universitetsjukhuset, Solna, Sweden.; Science for life laboratory, Karolinska Institutet, Solna, Sweden.
Siscovick DS; The New York Academy of Medicine, New York, NY, United States of America.
Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany.
Sun L; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Swertz M; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Tajuddin SM; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Teo YY; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore, Singapore.; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore, Singapore.
Tham YC; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.
Tönjes A; Department of Medicine; University of Leipzig, Leipzig, Germany.
Wareham NJ; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Willemsen G; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Wilsgaard T; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Hingorani AD; Institute of Cardiovascular Science, University College London, London, United Kingdom.
Egan J; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Ferrucci L; Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, MD, United States of America.
Hovingh GK; Department of Vascular Medicine, Academic Medical Center, Amsterdam, Netherlands.
Jula A; National Institute for Health and Welfare (THL), Helsinki, Finland.
Kivimaki M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.
Kumari M; Department of Epidemiology and Public Health, University College London, London, United Kingdom.; Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom.
NjølstadI ; Dept of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway.
Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Serrano Ríos M; Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
Stumvoll M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Watkins H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Aung T; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Blüher M; Department of Medicine; University of Leipzig, Leipzig, Germany.
Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, United States of America.
Boomsma DI; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Bornstein SR; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Chambers JC; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.
Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.
Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Cheng CY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Cucca F; Istituto di Ricerca Genetica e Biomedica (IRGB), CNR, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Università di Sassari, Italy.
de Geus EJC; Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia.
Evans MK; Health Disparities Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Fornage M; Brown Foundation Institute of Molecular Medicine, Division of Epidemiology, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, United States of America.
Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
Froguel P; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, United Kingdom.; CNRS 8199-Lille University, France.
Groop L; Lund University Diabetes Centre, Lund University, Lund, Sweden.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.
Gross MD; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States of America.
Harris TB; National Institute on Aging, Bethesda, MD, United States of America.
Hayward C; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, Singapore.
Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA, United States of America.
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.
Kim BJ; Division of Structural and Functional Genomics, Center for Genome Science, Korean National Institute of Health, Osong, Chungchungbuk-do, South Korea.
Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.
Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Southall, Middlesex, United Kingdom.; Imperial College Healthcare NHS Trust, London, United Kingdom.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, United Kingdom.
Körner A; Center of Pediatric Research, University Hospital for Children & Adolescents, Dept. of Women's & Child Health, University of Leipzig, Leipzig, Germany.; LIFE Child, LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.
Kuh D; MRC Unit for Lifelong Health & Ageing, London, United Kingdom.
Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
Lin X; The Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu Y; Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University, Winston-Salem, NC, United States of America.
Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.; The Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
März W; Vth Department of Medicine, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.
McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, United Kingdom.
Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Ong KK; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Insitutet, Stockholm, Sweden.
Pereira MA; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, United States of America.
Peters A; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.
Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States of America.
Sabanayagam C; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.
Sale M; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, United States of America.
Saleheen D; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, United States of America.; Center for Non-Communicable Diseases, Karachi, Pakistan.
Saltevo J; Department of Medicine, Central Hospital, Central Finland, Jyväskylä, Finland.
Schwarz PE; Dept of Medicine III, University of Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Sheu WHH; Division of Endocrine and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.
Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom.
Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tuomilehto J; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland.; Dasman Diabetes Institute, Dasman, Kuwait.; Centre for Vascular Prevention, Danube-University Krems, Krems, Austria.; Saudi Diabetes Research Group, King Abdulaziz University, Fahd Medical Research Center, Jeddah, Saudi Arabia.
van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, United States of America.
Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland.
Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.
Wong TY; Singapore Eye Research Institute, The Academia Level 6, Discovery Tower, Singapore, Singapore.; Ophthalmology and Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Singapore National Eye Centre, Singapore, Singapore.
Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung City, Taiwan.
Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States of America.; Division of Cancer Control and Population Sciences,University of Pittsburgh Cancer Institute, Pittsburgh, PA, United States of America.
Zonderman AB; Laboratory of Epidemiology & Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States of America.
Soranzo N; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Department of Haematology, University of Cambridge, Cambridge, United Kingdom.; The National Institute for Health Research Blood and Transplant Unit (NIHR BTRU) in Donor Health and Genomics at the University of Cambridge, United Kingdom.
Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Roberts DJ; Biomedical Research Centre Oxford Haematology Theme and Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, United Kingdom.; NHS Blood and Transplant, Headington, Oxford, United Kingdom.
Florez JC; Harvard Medical School, Boston, MA, United States of America.; Diabetes Unit and Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America.
Sladek R; Department of Medicine, McGill University, Montreal, Quebec, Canada.
Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, MA, United States of America.; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, United States of America.
Morris AP; Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Department of Biostatistics, University of Liverpool, Liverpool, United Kingdom.
Tai ES; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Selvin E; Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.; Division of General Internal Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.; Welch Center for Prevention, Epidemiology and Clinical Research, The Johns Hopkins University, Baltimore, MD, United States of America.
Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, United States of America.
Langenberg C; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom.
BarrosoI ; Department of Human Genetics, Wellcome Trust Sanger Institute, Genome Campus, Hinxton, Cambridge, United Kingdom.; Institute of Metabolic Science, University of Cambridge, Cambridge, United Kingdom.
Meigs JB; Division of General Internal Medicine, Massachusetts General Hospital, Boston, MA, United States of America.; Harvard Medical School, Boston, MA, United States of America.; Programs in Metabolism and Medical & Population Genetics, Broad Institute, Cambridge, MA, United States of America. - Pokaż więcej
- Corporate Authors:
-
EPIC-CVD Consortium
EPIC-InterAct Consortium
Lifelines Cohort Study - Źródło:
- PLoS medicine [PLoS Med] 2017 Sep 12; Vol. 14 (9), pp. e1002383. Date of Electronic Publication: 2017 Sep 12 (Print Publication: 2017).
- Typ publikacji:
- Journal Article; Meta-Analysis
- MeSH Terms:
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Genetic Variation *
Genome-Wide Association Study*
Diabetes Mellitus, Type 2/*diagnosis
Diabetes Mellitus, Type 2/*genetics
Glycated Hemoglobin/*genetics
Diabetes Mellitus, Type 2/epidemiology ; Glycated Hemoglobin/metabolism ; Humans ; Phenotype ; Risk
Czasopismo naukowe