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Wyświetlanie 1-20 z 27
Tytuł:
iPSC-derived natural killer cells expressing the FcγR fusion CD64/16A can be armed with antibodies for multitumor antigen targeting
Autorzy:
Jeffrey S Miller
Martin Hosking
Ryan Bjordahl
Bahram Valamehr
Soheila Shirinbak
Zachary Davis
Bryan Hancock
Bruce Walcheck
Kristin M Snyder
Kate J Dixon
Geoffrey Hart
Melissa Khaw
Anders Matson
Jianming Wu
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Temat:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 12 (2023)
Opis pliku:
electronic resource
Relacje:
https://jitc.bmj.com/content/11/12/e007280.full; https://doaj.org/toc/2051-1426
Dostęp URL:
https://doaj.org/article/5fb4875136e348289f045144cde7592c  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Quadruple gene-engineered natural killer cells enable multi-antigen targeting for durable antitumor activity against multiple myeloma
Autorzy:
Frank Cichocki
Ryan Bjordahl
Jodie P. Goodridge
Sajid Mahmood
Svetlana Gaidarova
Ramzey Abujarour
Zachary B. Davis
Aimee Merino
Katie Tuininga
Hongbo Wang
Akhilesh Kumar
Brian Groff
Alec Witty
Greg Bonello
Janel Huffman
Thomas Dailey
Tom T. Lee
Karl-Johan Malmberg
Bruce Walcheck
Uta Höpken
Armin Rehm
Bahram Valamehr
Jeffrey S. Miller
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Temat:
Science
Źródło:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2041-1723
Dostęp URL:
https://doaj.org/article/cf51e4650f724761987dbfd84d67e91a  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
169 Off-the-shelf, engineered iPSC-derived NK cells mediate potent cytotoxic activity against primary glioblastoma cells and promote durable long-term survival in vivo
Autorzy:
Jeffrey Miller
Tom Lee
Ryan Bjordahl
Frank Cichocki
Jianfang Ning
Zachary Davis
Katie Tuininga
Hongbo Wang
Paul Rogers
Moyar Ge
Bob Valamehr
Clark Chen
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Temat:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2051-1426
Dostęp URL:
https://doaj.org/article/7e590c8269394cfcbf37a33cdf6a8df5  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
114 Preclinical development of a novel iPSC-derived CAR-MICA/B NK cell immunotherapy to overcome solid tumor escape from NKG2D-mediated mechanisms of recognition and killing
Autorzy:
Tom Lee
John Goulding
Mochtar Pribadi
Robert Blum
Wen-I Yeh
Yijia Pan
Svetlana Gaidarova
Chia-Wei Chang
Hui-Yi Chu
Ellen Liu
Shohreh Sikaroodi
Lucas Ferrari de Andrade
Lauren Fong
Janel Huffman
Ryan Bjordahl
Kai Wucherpfennig
Bahram Valamehr
Pokaż więcej
Temat:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2051-1426
Dostęp URL:
https://doaj.org/article/dc7d6b71029847c78280719e191b744e  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
155 iPSC-derived NK cells mediate robust anti-tumor activity against glioblastoma
Autorzy:
Jeffrey Miller
Tom Lee
Ryan Bjordahl
Frank Cichocki
Jianfang Ning
Zachary Davis
Katie Tuininga
Hongbo Wang
Paul Rogers
Moyar Ge
Bob Valamehr
Clark Chen
Pokaż więcej
Temat:
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Źródło:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2051-1426
Dostęp URL:
https://doaj.org/article/3aa43b6ddf544eb3908effa905139b90  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Correction: Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.
Autorzy:
Hasan S; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Neurodegenerative Disease, UK Dementia Research Institute, Institute of Neurology, University College London, London, UK.; Augusta University, University of Georgia Medical Partnership, Athens, GA, USA.
Fernandopulle MS; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Medical Scientist Training Program, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Humble SW; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, OX1 3QU, Oxford, UK.
Frankenfield AM; Department of Chemistry, George Washington University, Washington, DC, USA.
Li H; Department of Chemistry, George Washington University, Washington, DC, USA.
Prestil R; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Johnson KR; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.
Ryan BJ; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, OX1 3QU, Oxford, UK.
Wade-Martins R; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, OX1 3QU, Oxford, UK.
Ward ME; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA. .
Hao L; Department of Chemistry, George Washington University, Washington, DC, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2023 Dec 18; Vol. 18 (1), pp. 96. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji:
Published Erratum
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Multi-modal proteomic characterization of lysosomal function and proteostasis in progranulin-deficient neurons.
Autorzy:
Hasan S; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Neurodegenerative Disease, UK Dementia Research Institute, Institute of Neurology, University College London, London, UK.; Augusta University, University of Georgia Medical Partnership, Athens, GA, USA.
Fernandopulle MS; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Medical Scientist Training Program, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Humble SW; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK.
Frankenfield AM; Department of Chemistry, George Washington University, Washington, DC, USA.
Li H; Department of Chemistry, George Washington University, Washington, DC, USA.
Prestil R; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Johnson KR; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA.
Ryan BJ; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK.
Wade-Martins R; Department of Physiology, Anatomy and Genetics, Oxford Parkinson's Disease Centre, Kavli Institute for Nanoscience Discovery, University of Oxford, Dorothy Crowfoot Hodgkin Building, South Parks Road, Oxford, OX1 3QU, UK.
Ward ME; National Institute of Neurological, Disorders and Stroke (NINDS), National Institutes of Health (NIH), Bethesda, MD, USA. .
Hao L; Department of Chemistry, George Washington University, Washington, DC, USA. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2023 Nov 16; Vol. 18 (1), pp. 87. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
Frontotemporal Dementia*/genetics
Frontotemporal Dementia*/metabolism
Induced Pluripotent Stem Cells*/metabolism
Animals ; Mice ; Humans ; Progranulins/genetics ; Intercellular Signaling Peptides and Proteins/metabolism ; Proteostasis ; Proteomics ; Lysosomes/metabolism ; Neurons/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Prognostication in Poststroke Aphasia: Perspectives of Significant Others of People With Aphasia on Receiving Information About Recovery.
Autorzy:
Cheng BBY; School of Health and Rehabilitation Sciences, The University of Queensland, St. Lucia, Australia.; Queensland Aphasia Research Centre, The University of Queensland, Herston, Australia.
Ryan BJ; School of Health and Rehabilitation Sciences, The University of Queensland, St. Lucia, Australia.; Queensland Aphasia Research Centre, The University of Queensland, Herston, Australia.; NHMRC Centre of Research Excellence in Aphasia Recovery and Rehabilitation, La Trobe University, Bundoora, Victoria, Australia.; Discipline of Clinical Psychology, Graduate School of Health, University of Technology Sydney, Ultimo, New South Wales, Australia.
Copland DA; School of Health and Rehabilitation Sciences, The University of Queensland, St. Lucia, Australia.; Queensland Aphasia Research Centre, The University of Queensland, Herston, Australia.; NHMRC Centre of Research Excellence in Aphasia Recovery and Rehabilitation, La Trobe University, Bundoora, Victoria, Australia.
Wallace SJ; School of Health and Rehabilitation Sciences, The University of Queensland, St. Lucia, Australia.; Queensland Aphasia Research Centre, The University of Queensland, Herston, Australia.; NHMRC Centre of Research Excellence in Aphasia Recovery and Rehabilitation, La Trobe University, Bundoora, Victoria, Australia.
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Źródło:
American journal of speech-language pathology [Am J Speech Lang Pathol] 2022 Mar 10; Vol. 31 (2), pp. 896-911. Date of Electronic Publication: 2022 Jan 20.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Aphasia*/diagnosis
Aphasia*/etiology
Disabled Persons*
Communication ; Humans ; Surveys and Questionnaires
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Novel Facet of an Old Dietary Molecule? Direct Influence of Caffeine on Glucose and Biogenic Amine Handling by Human Adipocytes.
Autorzy:
Ahmed WH; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.; Université Paul Sabatier, I2MC-UPS, CHU Rangueil, CEDEX 4, 31432 Toulouse, France.
Boulet N; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.; Université Paul Sabatier, I2MC-UPS, CHU Rangueil, CEDEX 4, 31432 Toulouse, France.
Briot A; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.; Université Paul Sabatier, I2MC-UPS, CHU Rangueil, CEDEX 4, 31432 Toulouse, France.
Ryan BJ; School Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.
Kinsella GK; School Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.
O'Sullivan J; School of Dental Science, Trinity College, D02 PN40 Dublin 2, Ireland.
Les F; Department of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Villanueva de Gállego, 50830 Zaragoza, Spain.
Mercader-Barceló J; Molecular Biology and One Health (MOLONE) Research Group, Department of Fundamental Biology and Health Sciences, MOLONE, University of the Balearic Islands, 07120 Palma, Spain.; Balearic Islands Health Research Institute (IdISBa), 07120 Palma, Spain.
Henehan GTM; School Food Science & Environmental Health, Technological University of Dublin, DOIWD85, D07 ADY7 Dublin, Ireland.
Carpéné C; Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM U1048), I2MC, CEDEX 4, 31432 Toulouse, France.; Université Paul Sabatier, I2MC-UPS, CHU Rangueil, CEDEX 4, 31432 Toulouse, France.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2021 Jun 23; Vol. 26 (13). Date of Electronic Publication: 2021 Jun 23.
Typ publikacji:
Journal Article
MeSH Terms:
Adipocytes/*drug effects
Biogenic Amines/*metabolism
Caffeine/*pharmacology
Glucose/*metabolism
Lipogenesis/*drug effects
Monoamine Oxidase/*metabolism
Adipose Tissue/drug effects ; Adipose Tissue/metabolism ; Animals ; Benzylamines/metabolism ; Biological Transport/drug effects ; Deoxyglucose/metabolism ; Humans ; Insulin/metabolism ; Lipolysis/drug effects ; Mice ; Rats ; Xanthines/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation.
Autorzy:
Okarmus J; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 21, 5000, Odense C, Denmark.
Bogetofte H; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 21, 5000, Odense C, Denmark.
Schmidt SI; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 21, 5000, Odense C, Denmark.
Ryding M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 21, 5000, Odense C, Denmark.
García-López S; Department of Molecular Biology and Center of Molecular Biology Severo Ochoa, Autonomous University of Madrid-C.S.I.C Campus Cantoblanco, Madrid, Spain.
Ryan BJ; Oxford Parkinson's Disease Centre, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
Martínez-Serrano A; Department of Molecular Biology and Center of Molecular Biology Severo Ochoa, Autonomous University of Madrid-C.S.I.C Campus Cantoblanco, Madrid, Spain.
Hyttel P; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Grønnegaardsvej 7, 1870, Frederiksberg C, Denmark.
Meyer M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, J.B. Winsløws Vej 21, 5000, Odense C, Denmark. .; BRIDGE - Brain Research Inter-Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, J.B. Winsløws Vej 19, 5000, Odense C, Denmark. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jun 24; Vol. 10 (1), pp. 10278. Date of Electronic Publication: 2020 Jun 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dopaminergic Neurons/*pathology
Lysosomes/*pathology
Parkinsonian Disorders/*pathology
Ubiquitin-Protein Ligases/*genetics
Cell Line ; Dopaminergic Neurons/cytology ; Dopaminergic Neurons/ultrastructure ; Gene Knockdown Techniques ; Humans ; Induced Pluripotent Stem Cells ; Loss of Function Mutation ; Lysosomes/ultrastructure ; Microscopy, Electron, Transmission ; Parkinsonian Disorders/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The Statistical Optimisation of Recombinant β-glucosidase Production through a Two-Stage, Multi-Model, Design of Experiments Approach.
Autorzy:
Uhoraningoga A; School of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, Dublin D07 ADY7, Ireland.
Kinsella GK; School of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, Dublin D07 ADY7, Ireland.
Frias JM; School of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, Dublin D07 ADY7, Ireland.
Henehan GT; School of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, Dublin D07 ADY7, Ireland.
Ryan BJ; School of Food Science and Environmental Health, College of Sciences and Health, Technological University Dublin, Dublin D07 ADY7, Ireland. barry.ryan@dit.ie.
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Źródło:
Bioengineering (Basel, Switzerland) [Bioengineering (Basel)] 2019 Jul 18; Vol. 6 (3). Date of Electronic Publication: 2019 Jul 18.
Typ publikacji:
Journal Article
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Theobromine and related methylxanthines as inhibitors of Primary Amine Oxidase.
Autorzy:
Shanahan P; Applied Enzymology Group, School of Food Science and Environmental Health, College of Science and Health, Dublin Institute of Technology, Dublin, Ireland.
O'Sullivan J; School of Dental Science, Trinity College Dublin, Dublin, Ireland.
Tipton KF; School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.
Kinsella GK; Applied Enzymology Group, School of Food Science and Environmental Health, College of Science and Health, Dublin Institute of Technology, Dublin, Ireland.
Ryan BJ; Applied Enzymology Group, School of Food Science and Environmental Health, College of Science and Health, Dublin Institute of Technology, Dublin, Ireland.
Henehan GTM; Applied Enzymology Group, School of Food Science and Environmental Health, College of Science and Health, Dublin Institute of Technology, Dublin, Ireland.
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Źródło:
Journal of food biochemistry [J Food Biochem] 2019 Feb; Vol. 43 (2), pp. e12697. Date of Electronic Publication: 2018 Oct 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme Inhibitors/*chemistry
Oxidoreductases Acting on CH-NH2 Group Donors/*antagonists & inhibitors
Theobromine/*chemistry
Xanthines/*chemistry
Animals ; Cattle ; Kinetics ; Oxidoreductases Acting on CH-NH2 Group Donors/chemistry ; Oxidoreductases Acting on CH-NH2 Group Donors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Accessibility and Applicability of Currently Available e-Mental Health Programs for Depression for People With Poststroke Aphasia: Scoping Review.
Autorzy:
Clunne SJ; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Ryan BJ; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Hill AJ; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Brandenburg C; School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia.
Kneebone I; Discipline of Clinical Psychology, Graduate School of Health, University of Technology, Sydney, Ultimo, Australia.
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Źródło:
Journal of medical Internet research [J Med Internet Res] 2018 Dec 04; Vol. 20 (12), pp. e291. Date of Electronic Publication: 2018 Dec 04.
Typ publikacji:
Journal Article; Systematic Review
MeSH Terms:
Mental Health*
Surveys and Questionnaires*
Telemedicine*
Aphasia/*complications
Depression/*complications
Depression/*therapy
Stroke/*complications
Survivors/*psychology
Aphasia/psychology ; Cost-Benefit Analysis ; Depression/psychology ; Disabled Persons/psychology ; Humans ; Quality of Life ; Stroke/psychology
Czasopismo naukowe
Pełny tekstSzczegóły
Tytuł:
The Goldilocks Approach: A Review of Employing Design of Experiments in Prokaryotic Recombinant Protein Production.
Autorzy:
Uhoraningoga A; Dublin Institute of Technology, Dublin D01 HV58, Ireland. .
Kinsella GK; Dublin Institute of Technology, Dublin D01 HV58, Ireland. .
Henehan GT; Dublin Institute of Technology, Dublin D01 HV58, Ireland. .
Ryan BJ; Dublin Institute of Technology, Dublin D01 HV58, Ireland. Barry.Ryan@dit.ie.
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Źródło:
Bioengineering (Basel, Switzerland) [Bioengineering (Basel)] 2018 Oct 19; Vol. 5 (4). Date of Electronic Publication: 2018 Oct 19.
Typ publikacji:
Journal Article; Review
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.
Autorzy:
Lai MC; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.; European Molecular Biology Laboratory, 69117, Heidelberg, Germany.
Bechy AL; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.
Denk F; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.
Collins E; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.
Gavriliouk M; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.
Zaugg JB; European Molecular Biology Laboratory, 69117, Heidelberg, Germany.
Ryan BJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK.; Oxford Parkinson's Disease Centre, University of Oxford, Oxford, OX1 3QX, UK.
Wade-Martins R; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK. .; Oxford Parkinson's Disease Centre, University of Oxford, Oxford, OX1 3QX, UK. .
Caffrey TM; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3QX, UK. .
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2017 Oct 30; Vol. 12 (1), pp. 79. Date of Electronic Publication: 2017 Oct 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Alternative Splicing/*genetics
Genetic Predisposition to Disease/*genetics
Parkinsonian Disorders/*genetics
tau Proteins/*genetics
Exons/genetics ; Haplotypes ; Humans ; Linkage Disequilibrium ; Polymorphism, Single Nucleotide ; Protein Isoforms/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease.
Autorzy:
Keane H; Oxford Parkinson's Disease Centre, Anatomy and Genetics, University of Oxford, OX1 3QX.; Department of Physiology, Anatomy and Genetics, University of Oxford, OX1 3QX.
Ryan BJ; Oxford Parkinson's Disease Centre, Anatomy and Genetics, University of Oxford, OX1 3QX.; Department of Physiology, Anatomy and Genetics, University of Oxford, OX1 3QX.
Jackson B; e-Therapeutics plc, Long Hanborough, OX29 8LN.
Whitmore A; e-Therapeutics plc, Long Hanborough, OX29 8LN.; Oxford Parkinson's Disease Centre and Networks Cluster, Keble College, Oxford, OX1 3PG.
Wade-Martins R; Oxford Parkinson's Disease Centre, Anatomy and Genetics, University of Oxford, OX1 3QX.; Department of Physiology, Anatomy and Genetics, University of Oxford, OX1 3QX.
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Źródło:
Scientific reports [Sci Rep] 2015 Nov 26; Vol. 5, pp. 17004. Date of Electronic Publication: 2015 Nov 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Models, Biological*
Protein Interaction Maps*
Parkinson Disease/*metabolism
Parkinson Disease/*pathology
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Adaptor Proteins, Signal Transducing/metabolism ; Apoptosis Regulatory Proteins ; Autophagy/drug effects ; Cell Line, Tumor ; Cytoprotection/drug effects ; Gene Knockdown Techniques ; Humans ; Microtubule-Associated Proteins/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Neurotoxins/toxicity ; Phagosomes/drug effects ; Phagosomes/metabolism ; Proteolysis/drug effects ; RNA, Small Interfering/metabolism ; RNA-Binding Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
AltitudeOmics: rapid hemoglobin mass alterations with early acclimatization to and de-acclimatization from 5260 m in healthy humans.
Autorzy:
Ryan BJ; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America.
Wachsmuth NB; Department of Sports Medicine/Sports Physiology, University of Bayreuth, Bayreuth, Germany.
Schmidt WF; Department of Sports Medicine/Sports Physiology, University of Bayreuth, Bayreuth, Germany.
Byrnes WC; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America.
Julian CG; Altitude Research Center, Department of Emergency Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Lovering AT; Department of Human Physiology, University of Oregon, Eugene, Oregon, United States of America.
Subudhi AW; Altitude Research Center, Department of Emergency Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America; Department of Biology, University of Colorado Colorado Springs, Colorado Springs, Colorado, United States of America.
Roach RC; Altitude Research Center, Department of Emergency Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
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Źródło:
PloS one [PLoS One] 2014 Oct 01; Vol. 9 (10), pp. e108788. Date of Electronic Publication: 2014 Oct 01 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Altitude*
Acclimatization/*physiology
Erythropoiesis/*physiology
Hemoglobins/*analysis
Female ; Humans ; Male ; Young Adult
Czasopismo naukowe
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Wyświetlanie 1-20 z 27

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