- Tytuł :
-
Imatinib mesylate (Gleevec) enhances mature osteoclast
apoptosis and suppresses osteoclast bone resorbing activity. - Autorzy :
- Źródło :
- European journal of pharmacology [Eur J Pharmacol] 2006 Dec 03; Vol. 551 (1-3), pp. 27-33. Date of Electronic Publication: 2006 Sep 16.
- Typ publikacji :
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms :
-
Apoptosis /*drug effects
Bone Density Conservation Agents/*pharmacology
Bone Remodeling/*drug effects
Bone Resorption/*prevention & control
Osteoclasts/*drug effects
Piperazines/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Pyrimidines/*pharmacology
Amino Acid Chloromethyl Ketones/pharmacology ; Animals ; Benzamides ; Caspase Inhibitors ; Cell Survival/drug effects ; Cells, Cultured ; Cysteine Proteinase Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Imatinib Mesylate ; Interleukin-1alpha/pharmacology ; Macrophage Colony-Stimulating Factor/pharmacology ; Osteoclasts/metabolism ; RANK Ligand/pharmacology ; Rabbits ; Time Factors -
Czasopismo naukowe