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Tytuł :
Production and characterization of mouse monoclonal antibodies to wild-type and oncogenic FLI-1 proteins.
Autorzy :
Melot T; Laboratoire de Génétique des Tumeurs, INSERM U 434, Paris.
Gruel N
Doubeikovski A
Sevenet N
Teillaud JL
Delattre O
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Źródło :
Hybridoma [Hybridoma] 1997 Oct; Vol. 16 (5), pp. 457-64.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Proto-Oncogene Proteins*
Antibodies, Monoclonal/*biosynthesis
DNA-Binding Proteins/*immunology
Trans-Activators/*immunology
Animals ; Antibodies, Monoclonal/chemistry ; Antibodies, Monoclonal/metabolism ; DNA/metabolism ; DNA-Binding Proteins/metabolism ; Enzyme-Linked Immunosorbent Assay ; Fluorescent Antibody Technique, Indirect ; Humans ; Mice ; Oncogene Proteins, Fusion/immunology ; Oncogene Proteins, Fusion/metabolism ; Proto-Oncogene Protein c-fli-1 ; RNA-Binding Protein EWS ; Trans-Activators/metabolism ; Transcription Factors/immunology ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.
Autorzy :
Versteege I; Laboratoire de Pathologie Moléculaire des Cancers, Section de Recherche, Institut Curie, Paris, France.
Sévenet N
Lange J
Rousseau-Merck MF
Ambros P
Handgretinger R
Aurias A
Delattre O
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Źródło :
Nature [Nature] 1998 Jul 09; Vol. 394 (6689), pp. 203-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Mapping*
Chromosomes, Human, Pair 22*
DNA-Binding Proteins/*genetics
Rhabdoid Tumor/*genetics
Transcription Factors/*genetics
Child ; Chromosomal Proteins, Non-Histone ; Chromosome Deletion ; Frameshift Mutation ; Humans ; Infant ; Infant, Newborn ; Mutation ; SMARCB1 Protein ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers.
Autorzy :
Sévenet N; Laboratoire de Pathologie Moléculaire des Cancers, INSERM U 509, Institut Curie, Paris, France.
Sheridan E
Amram D
Schneider P
Handgretinger R
Delattre O
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Źródło :
American journal of human genetics [Am J Hum Genet] 1999 Nov; Vol. 65 (5), pp. 1342-8.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*genetics
Rhabdoid Tumor/*genetics
Chromosomal Proteins, Non-Histone ; DNA Mutational Analysis ; Female ; Genetic Markers ; Humans ; Male ; Molecular Sequence Data ; Mutation ; Pedigree ; SMARCB1 Protein ; Transcription Factors
Czasopismo naukowe
Tytuł :
Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations.
Autorzy :
Sévenet N; Laboratoire de Pathologie Moléculaire des Cancers, INSERM U509, Institut Curie, 26 rue d'Ulm, 75248 Paris cedex 05, France.
Lellouch-Tubiana A
Schofield D
Hoang-Xuan K
Gessler M
Birnbaum D
Jeanpierre C
Jouvet A
Delattre O
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Źródło :
Human molecular genetics [Hum Mol Genet] 1999 Dec; Vol. 8 (13), pp. 2359-68.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA, Neoplasm/*genetics
DNA-Binding Proteins/*genetics
Rhabdoid Tumor/*genetics
Chromatography, High Pressure Liquid ; Chromosomal Proteins, Non-Histone ; Chromosomes, Human, Pair 22/genetics ; Gene Deletion ; Genotype ; Humans ; Loss of Heterozygosity ; Phenotype ; Point Mutation ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; SMARCB1 Protein ; Transcription Factors
Czasopismo naukowe
Tytuł :
INI1 mutations in meningiomas at a potential hotspot in exon 9.
Autorzy :
Schmitz U; Department of Neuropathology, Charité, Humboldt University, Berlin, 13353, Germany.
Mueller W
Weber M
Sévenet N
Delattre O
von Deimling A
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Źródło :
British journal of cancer [Br J Cancer] 2001 Jan; Vol. 84 (2), pp. 199-201.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
DNA-Binding Proteins/*genetics
Exons/*genetics
Meningeal Neoplasms/*genetics
Meningioma/*genetics
Alleles ; Amino Acid Substitution ; Base Sequence ; Chromosomal Proteins, Non-Histone ; Chromosomes, Human, Pair 22/genetics ; DNA Mutational Analysis ; DNA, Neoplasm/chemistry ; DNA, Neoplasm/genetics ; Gene Frequency ; Humans ; Loss of Heterozygosity ; Meningeal Neoplasms/pathology ; Meningioma/pathology ; Mutation ; Point Mutation ; Polymorphism, Genetic ; Polymorphism, Single-Stranded Conformational ; SMARCB1 Protein ; Transcription Factors
Czasopismo naukowe
Tytuł :
Analysis of the expression of cell cycle regulators in Ewing cell lines: EWS-FLI-1 modulates p57KIP2and c-Myc expression.
Autorzy :
Dauphinot L; INSERM U509, Laboratoire de Pathologie Moléculaire des Cancers, Institut Curie, 26 rue d'Ulm, 75248 Paris Cedex 05, France.
De Oliveira C
Melot T
Sevenet N
Thomas V
Weissman BE
Delattre O
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Źródło :
Oncogene [Oncogene] 2001 May 31; Vol. 20 (25), pp. 3258-65.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Cycle Proteins/*metabolism
Nuclear Proteins/*metabolism
Oncogene Proteins, Fusion/*metabolism
Proto-Oncogene Proteins c-myc/*metabolism
Sarcoma, Ewing/*etiology
Transcription Factors/*metabolism
Base Sequence ; Cell Cycle ; Cell Transformation, Neoplastic ; Cyclin-Dependent Kinase Inhibitor p57 ; Down-Regulation ; Humans ; Molecular Sequence Data ; Nuclear Proteins/genetics ; Promoter Regions, Genetic ; Proto-Oncogene Protein c-fli-1 ; RNA-Binding Protein EWS ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Atypical teratoid and rhabdoid tumor. Report of a congenital case].
Autorzy :
Fernandez C; Service d'Anatomie Pathologique et de Neuropathologie, CHU Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05.
Sévenet N
Bouvier-Labit C
Lena G
Figarella-Branger D
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Transliterated Title :
Tumeur rhabdoïde et tératoïde atypique. A propos d'un cas congénital.
Źródło :
Annales de pathologie [Ann Pathol] 2001 Jun; Vol. 21 (3), pp. 259-62.
Typ publikacji :
Case Reports; English Abstract; Journal Article
MeSH Terms :
Brain Neoplasms/*congenital
Rhabdoid Tumor/*congenital
Teratoma/*congenital
Actins/analysis ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Child ; DNA, Neoplasm/genetics ; Humans ; Immunohistochemistry ; Male ; Mucin-1/analysis ; Mutation ; Neoplasms, Multiple Primary/congenital ; Neoplasms, Multiple Primary/genetics ; Neoplasms, Multiple Primary/pathology ; Neuroectodermal Tumors, Primitive/pathology ; Rhabdoid Tumor/genetics ; Rhabdoid Tumor/pathology ; Teratoma/genetics ; Teratoma/pathology ; Vimentin/analysis
Czasopismo naukowe
Tytuł :
Congenital disseminated malignant rhabdoid tumor and cerebellar tumor mimicking medulloblastoma in monozygotic twins: pathologic and molecular diagnosis.
Autorzy :
Fernandez C; Service d'Anatomie Pathologique et de Neuropathologie, CHU Timone, 264 rue Saint-Pierre, 13385 Marseille cédex 05, France.
Bouvier C
Sévenet N
Liprandi A
Coze C
Lena G
Figarella-Branger D
Pokaż więcej
Źródło :
The American journal of surgical pathology [Am J Surg Pathol] 2002 Feb; Vol. 26 (2), pp. 266-70.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Diseases in Twins*
Twins, Monozygotic*
Cerebellar Neoplasms/*pathology
Medulloblastoma/*pathology
Rhabdoid Tumor/*pathology
Spinal Neoplasms/*pathology
Biomarkers, Tumor/analysis ; Cerebellar Neoplasms/congenital ; Cerebellar Neoplasms/genetics ; DNA, Neoplasm/analysis ; Diagnosis, Differential ; Fatal Outcome ; Female ; Gene Deletion ; Germ-Line Mutation ; Humans ; Immunoenzyme Techniques ; Infant ; Magnetic Resonance Imaging ; Rhabdoid Tumor/congenital ; Rhabdoid Tumor/genetics ; Spinal Neoplasms/congenital ; Spinal Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Rhabdoid tumor of the kidney is a component of the rhabdoid predisposition syndrome.
Autorzy :
Lee HY; Department of Pathology, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899, Singapore. />Yoon CS
Sevenet N
Rajalingam V
Delattre O
Walford NQ
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Źródło :
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society [Pediatr Dev Pathol] 2002 Jul-Aug; Vol. 5 (4), pp. 395-9. Date of Electronic Publication: 2002 May 21.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Kidney Neoplasms/*genetics
Kidney Neoplasms/*pathology
Rhabdoid Tumor/*genetics
Rhabdoid Tumor/*pathology
Cerebellar Neoplasms/genetics ; Cerebellar Neoplasms/pathology ; Chromosomal Proteins, Non-Histone ; DNA-Binding Proteins/genetics ; Female ; Germ-Line Mutation/genetics ; Humans ; Immunohistochemistry ; Infant ; Kidney Neoplasms/metabolism ; Lung Neoplasms/secondary ; Male ; Pedigree ; Pleural Neoplasms/genetics ; Pleural Neoplasms/secondary ; Polymerase Chain Reaction ; Rhabdoid Tumor/metabolism ; SMARCB1 Protein ; Transcription Factors
Czasopismo naukowe
Tytuł :
Comparative genomic hybridization detects specific cytogenetic abnormalities in pediatric ependymomas and choroid plexus papillomas.
Autorzy :
Grill J; Department of Pediatric Oncology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France.
Avet-Loiseau H
Lellouch-Tubiana A
Sévenet N
Terrier-Lacombe MJ
Vénuat AM
Doz F
Sainte-Rose C
Kalifa C
Vassal G
Pokaż więcej
Źródło :
Cancer genetics and cytogenetics [Cancer Genet Cytogenet] 2002 Jul 15; Vol. 136 (2), pp. 121-5.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Aberrations*
Nucleic Acid Hybridization*
Brain Neoplasms/*genetics
Choroid Plexus Neoplasms/*genetics
Ependymoma/*genetics
Papilloma/*genetics
Child ; Child, Preschool ; Chromosome Deletion ; Chromosomes, Human, Pair 22 ; Humans ; Infant ; Male
Czasopismo naukowe
Tytuł :
Regulation of bone resorption and osteoclast survival by nitric oxide: possible involvement of NMDA-receptor.
Autorzy :
Mentaverri R; Groupe d'Etude des Mécanismes de la Résorption Osseuse, Université de Picardie-Jules Verne, Laboratoire de pharmacie clinique, 1, rue des Louvels, 80037 Amiens, France. />Kamel S
Wattel A
Prouillet C
Sevenet N
Petit JP
Tordjmann T
Brazier M
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Źródło :
Journal of cellular biochemistry [J Cell Biochem] 2003 Apr 15; Vol. 88 (6), pp. 1145-56.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Resorption*
Nitric Oxide/*physiology
Osteoclasts/*physiology
Receptors, N-Methyl-D-Aspartate/*physiology
Animals ; Apoptosis/drug effects ; Benzoates/pharmacology ; Calcium/metabolism ; Cell Survival ; Cells, Cultured ; Dizocilpine Maleate/pharmacology ; Dose-Response Relationship, Drug ; Imidazoles/pharmacology ; Nitric Oxide/biosynthesis ; Nitric Oxide Synthase/biosynthesis ; Nitric Oxide Synthase Type I ; Osteoclasts/drug effects ; Osteoclasts/metabolism ; Rabbits ; Receptors, N-Methyl-D-Aspartate/drug effects ; Receptors, N-Methyl-D-Aspartate/metabolism
Czasopismo naukowe
Tytuł :
DNA microarrays in clinical practice: past, present, and future.
Autorzy :
Sevenet N; Plateforme de Génomique, Service de Biochimie et de Biologie Moléculaire, Hôpital Lariboisière (AP-HP), 2, rue Ambroise Paré, F-75010 Paris, France. nicolas.sevenet@lrb.ap-hop-paris.fr
Cussenot O
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Źródło :
Clinical and experimental medicine [Clin Exp Med] 2003 May; Vol. 3 (1), pp. 1-3.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Oligonucleotide Array Sequence Analysis*
Gene Expression ; Humans ; Prognosis
Czasopismo naukowe
Tytuł :
In vivo antitumor activity of S16020, a topoisomerase II inhibitor, and doxorubicin against human brain tumor xenografts.
Autorzy :
Vassal G; UPRES EA 3535 Pharmacology and New Treatments of Cancers, Institut Gustave-Roussy, Villejuif, France. />Merlin JL
Terrier-Lacombe MJ
Grill J
Parker F
Sainte-Rose C
Aubert G
Morizet J
Sévenet N
Poullain MG
Lucas C
Kalifa C
Pokaż więcej
Źródło :
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2003 May; Vol. 51 (5), pp. 385-94. Date of Electronic Publication: 2003 Mar 22.
Typ publikacji :
Journal Article
MeSH Terms :
Topoisomerase II Inhibitors*
Carbazoles/*pharmacology
Cerebellar Neoplasms/*drug therapy
Doxorubicin/*pharmacology
Glioblastoma/*drug therapy
Medulloblastoma/*drug therapy
Multidrug Resistance-Associated Proteins/*biosynthesis
Pyridines/*pharmacology
Animals ; Cerebellar Neoplasms/pathology ; Cerebellar Neoplasms/veterinary ; Drug Therapy, Combination ; Female ; Gene Expression Regulation ; Glioblastoma/pathology ; Glioblastoma/veterinary ; Medulloblastoma/pathology ; Medulloblastoma/veterinary ; Mice ; Mice, Nude ; Multidrug Resistance-Associated Proteins/pharmacology ; Reverse Transcriptase Polymerase Chain Reaction ; Transplantation, Heterologous
Czasopismo naukowe
Tytuł :
Breast cancer cell line MDA-MB 231 exerts a potent and direct anti-apoptotic effect on mature osteoclasts.
Autorzy :
Gallet M; Unité d'Etude des Mécanismes de la Résorption Osseuse, UPRES-EA 2086, Faculté de Pharmacie, 1, rue des Louvels, 80037 Amiens Cedex, France. />Sévenet N
Dupont C
Brazier M
Kamel S
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2004 Jun 25; Vol. 319 (2), pp. 690-6.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Breast Neoplasms/*pathology
Osteoclasts/*cytology
Animals ; Bone Resorption ; Cell Line, Tumor ; Culture Media, Conditioned ; Humans ; Macrophage Colony-Stimulating Factor/physiology ; Rabbits ; Signal Transduction
Czasopismo naukowe
Tytuł :
[Breast carcinoma and genomic technology: contribution of DNA microarrays].
Autorzy :
Sévenet N; Plateforme de génomique, Service de biochimie et biologie moléculaire, Hôpital Lariboisière (AP-HP), 2, rue Ambroise Paré, 75010 Paris.
Cottu PH
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Transliterated Title :
Génomique et cancer du sein: apport des puces à ADN.
Źródło :
Bulletin du cancer [Bull Cancer] 2004 Dec 01; Vol. 91 Suppl 4, pp. S226-31.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Breast Neoplasms/*genetics
Oligonucleotide Array Sequence Analysis/*methods
Female ; Genetic Markers/genetics ; Humans
Czasopismo naukowe
Tytuł :
[Genetic factors and colorectal cancers development: therapeutic impact].
Autorzy :
Olschwang S; Institut Paoli-Calmettes, Centre Régional de Lutte Contre le Cancer, Provence-Alpes-Côte d'Azur, Inserm UMR 599, Marseille, France. />Viret F
Monges G
Seitz J
Sevenet N
Tiret E
Milano G
Birnbaum D
Bertucci F
Pokaż więcej
Transliterated Title :
Identification des facteurs génétiques associés à l'évolution des cancers coliques: impact sur la prise en charge thérapeutique.
Źródło :
Medecine sciences : M/S [Med Sci (Paris)] 2006 Jan; Vol. 22 Spec No 1, pp. 45-9.
Typ publikacji :
English Abstract; Journal Article; Review
MeSH Terms :
Colorectal Neoplasms/*drug therapy
Colorectal Neoplasms/*genetics
Humans
Czasopismo naukowe
Tytuł :
Ability of breast cancer cell lines to stimulate bone resorbing activity of mature osteoclasts correlates with an anti-apoptotic effect mediated by macrophage colony stimulating factor.
Autorzy :
Gallet M; Unité d'Etude des Mécanismes de la Résorption Osseuse (UMRO), UPRES-EA 2086, Faculté de Pharmacie, 1, rue des Louvels, 80037, Amiens Cedex, France. />Mentaverri R
Sévenet N
Brazier M
Kamel S
Pokaż więcej
Źródło :
Apoptosis : an international journal on programmed cell death [Apoptosis] 2006 Nov; Vol. 11 (11), pp. 1909-21.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Bone Resorption/*metabolism
Breast Neoplasms/*metabolism
Macrophage Colony-Stimulating Factor/*metabolism
Osteoclasts/*cytology
Animals ; Apoptosis/drug effects ; Benzamides ; Cell Line, Tumor ; Culture Media, Conditioned ; Humans ; Imatinib Mesylate ; Macrophage Colony-Stimulating Factor/genetics ; Osteoclasts/metabolism ; Piperazines/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Pyrimidines/pharmacology ; RNA, Small Interfering ; Rabbits
Czasopismo naukowe
Tytuł :
Imatinib mesylate (Gleevec) enhances mature osteoclast apoptosis and suppresses osteoclast bone resorbing activity.
Autorzy :
El Hajj Dib I; Laboratoire de Biologie et Pharmacie Clinique, UPRES-EA 2086 and INSERM ERI-12, Faculty of Pharmacie, 1, rue des Louvels, 80037 Amiens Cedex, France.
Gallet M
Mentaverri R
Sévenet N
Brazier M
Kamel S
Pokaż więcej
Źródło :
European journal of pharmacology [Eur J Pharmacol] 2006 Dec 03; Vol. 551 (1-3), pp. 27-33. Date of Electronic Publication: 2006 Sep 16.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Bone Density Conservation Agents/*pharmacology
Bone Remodeling/*drug effects
Bone Resorption/*prevention & control
Osteoclasts/*drug effects
Piperazines/*pharmacology
Protein Kinase Inhibitors/*pharmacology
Pyrimidines/*pharmacology
Amino Acid Chloromethyl Ketones/pharmacology ; Animals ; Benzamides ; Caspase Inhibitors ; Cell Survival/drug effects ; Cells, Cultured ; Cysteine Proteinase Inhibitors/pharmacology ; Dose-Response Relationship, Drug ; Imatinib Mesylate ; Interleukin-1alpha/pharmacology ; Macrophage Colony-Stimulating Factor/pharmacology ; Osteoclasts/metabolism ; RANK Ligand/pharmacology ; Rabbits ; Time Factors
Czasopismo naukowe
Tytuł :
Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines.
Autorzy :
Chasseigneaux S; EA 3621, Faculté de Pharmacie, Université Paris 5, 4 avenue de l'Observatoire, 75270 Paris cedex 06, France.
Pastore M
Britton-Davidian J
Manié E
Stern MH
Callebert J
Catalan J
Casanova D
Belondrade M
Provansal M
Zhang Y
Bürkle A
Laplanche JL
Sévenet N
Lehmann S
Pokaż więcej
Źródło :
Archives of virology [Arch Virol] 2008; Vol. 153 (9), pp. 1693-702. Date of Electronic Publication: 2008 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Susceptibility*
Genetic Heterogeneity*
Neuroblastoma/*genetics
Prions/*metabolism
Animals ; Cell Line, Tumor ; Gene Expression ; Karyotyping ; Mice ; Neuroblastoma/metabolism ; Nucleic Acid Hybridization ; Prions/genetics
Czasopismo naukowe

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