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Tytuł:
The Transmembrane Protease Serine 2 (TMPRSS2) Non-Protease Domains Regulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike-Mediated Virus Entry.
Autorzy:
Strobelt R; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Adler J; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
Shaul Y; Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 7610001, Israel.
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Źródło:
Viruses [Viruses] 2023 Oct 19; Vol. 15 (10). Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Virus Internalization ; Peptide Hydrolases ; Serine ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Serine Endopeptidases/genetics ; Serine Endopeptidases/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Induction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR.
Autorzy:
Lu S; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Luo S; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, Beijing, People's Republic of China.
Liu C; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Li M; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, People's Republic of China.
An X; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Li M; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Hou J; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, Beijing, People's Republic of China.
Fan H; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Mao P; Department of Infectious Diseases, Fifth Medical Center of Chinese PLA General Hospital, Beijing, People's Republic of China.
Tong Y; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
Song L; Beijing Advanced Innovation Center for Soft Matter Science and Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, People's Republic of China.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2023 Dec; Vol. 12 (1), pp. 2151383.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies, Neutralizing*
COVID-19*/immunology
COVID-19*/therapy
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Animals ; Cricetinae ; Humans ; Mice ; Antibodies, Viral ; China ; Chlorocebus aethiops ; COVID-19 Vaccines ; Mesocricetus ; Pangolins/virology ; Spike Glycoprotein, Coronavirus/genetics ; Vero Cells
Czasopismo naukowe
Szczegóły
Tytuł:
Population immunity predicts evolutionary trajectories of SARS-CoV-2.
Autorzy:
Meijers M; Institute for Biological Physics, University of Cologne, Zülpicherstr. 77, 50937 Köln, Germany.
Ruchnewitz D; Institute for Biological Physics, University of Cologne, Zülpicherstr. 77, 50937 Köln, Germany.
Eberhardt J; Institute for Biological Physics, University of Cologne, Zülpicherstr. 77, 50937 Köln, Germany.
Łuksza M; Tisch Cancer Institute, Departments of Oncological Sciences and Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Lässig M; Institute for Biological Physics, University of Cologne, Zülpicherstr. 77, 50937 Köln, Germany. Electronic address: .
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Źródło:
Cell [Cell] 2023 Nov 09; Vol. 186 (23), pp. 5151-5164.e13. Date of Electronic Publication: 2023 Oct 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/epidemiology
COVID-19*/virology
SARS-CoV-2*/genetics
SARS-CoV-2*/physiology
Humans ; Vaccination ; Models, Genetic ; Epidemiological Monitoring
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Low-Entropy Hydration Shells at the Spike RBD's Binding Site May Reveal the Contagiousness of SARS-CoV-2 Variants.
Autorzy:
Yang L; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.; School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW 2006, Australia.
Guo S; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Hou C; School of Electronics and Information Engineering, Harbin Institute of Technology, Harbin 150080, China.
Jiang S; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Shi L; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Ma X; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.
Zheng B; Key Laboratory of Functional Inorganic Material Chemistry (Ministry of Education) and School of Chemistry and Materials Science, Heilongjiang University, Harbin 150001, China.
Fang Y; Department of Mathematics, Nanchang University, Nanchang 330031, China.
Ye L; School of System Design and Intelligent Manufacturing, Southern University of Science and Technology, Shenzhen 518055, China.
He X; National Key Laboratory of Science and Technology on Advanced Composites in Special Environments, Center for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150080, China.; Shenzhen STRONG Advanced Materials Research Institute Co., Ltd., Shenzhen 518035, China.
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Źródło:
Biomolecules [Biomolecules] 2023 Nov 07; Vol. 13 (11). Date of Electronic Publication: 2023 Nov 07.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Entropy ; Binding Sites ; Protein Binding ; Mutation ; Spike Glycoprotein, Coronavirus/chemistry
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Genomic and Epidemiologic Surveillance of SARS-CoV-2 in the Pandemic Period: Sequencing Network of the Lazio Region, Italy.
Autorzy:
Rueca M; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Berno G; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Agresta A; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Spaziante M; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Gruber CEM; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Fabeni L; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Giombini E; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Butera O; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Barca A; Direzione Regionale Salute E Integrazione Sociosanitaria, Area Promozione Della Salute E Prevenzione-Regione Lazio, 00145 Rome, Italy.
Scognamiglio P; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.; Direzione Regionale Salute E Integrazione Sociosanitaria, Area Promozione Della Salute E Prevenzione-Regione Lazio, 00145 Rome, Italy.
Girardi E; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Maggi F; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Valli MB; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Vairo F; National Institute for Infectious Diseases 'Lazzaro Spallanzani', IRCCS, 00149 Rome, Italy.
Sars-CoV-Lazio Genomic Surveillance Study Group
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Źródło:
Viruses [Viruses] 2023 Oct 31; Vol. 15 (11). Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/epidemiology
Humans ; Pandemics ; Genomics ; Epidemiological Monitoring ; Italy/epidemiology
Czasopismo naukowe
Szczegóły
Tytuł:
An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by β-coronavirus Non-structural Protein 1.
Autorzy:
Maurina SF; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
O'Sullivan JP; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Sharma G; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Pineda Rodriguez DC; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
MacFadden A; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA.
Cendali F; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA.
Henen MA; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA.
Vögeli B; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA.
Kieft JS; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, USA; RNA BioScience Initiative, University of Colorado School of Medicine, Aurora, CO, USA.
Glasgow A; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA.
Steckelberg AL; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2023 Oct 15; Vol. 435 (20), pp. 168259. Date of Electronic Publication: 2023 Sep 01.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Ribosomes*/metabolism
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Viral Nonstructural Proteins*/chemistry
Host-Pathogen Interactions*
Protein Biosynthesis*
Humans ; Amino Acids/chemistry ; Amino Acids/genetics ; RNA, Messenger/genetics ; Conserved Sequence
Czasopismo naukowe
Szczegóły
Tytuł:
Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.
Autorzy:
Kehrer T; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cupic A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ye C; Texas Biomedical Research Institute, San Antonio, TX 78227, USA.
Yildiz S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Bouhaddou M; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Microbiology, Immunology, and Molecular Genetics (MIMG), University of California, Los Angeles, Los Angeles, CA 90024, USA; Institute for Quantitative and Computational Biosciences (OCBio), University of California, Los Angeles, Los Angeles, CA 90024, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90024, USA.
Crossland NA; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02215, USA; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Barrall EA; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Cohen P; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Tseng A; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02215, USA; Department of Pathology and Laboratory Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Çağatay T; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Rathnasinghe R; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Flores D; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jangra S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Alam F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Mena I; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Aslam S; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Saqi A; Department of Pathology and Cell Biology, Columbia University Medical Center, New York, NY 10032, USA.
Rutkowska M; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Ummadi MR; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Pisanelli G; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Richardson RB; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Veit EC; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Fabius JM; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA.
Soucheray M; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Polacco BJ; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Ak B; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Marin A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Evans MJ; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Swaney DL; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Gonzalez-Reiche AS; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Sordillo EM; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
van Bakel H; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Icahn Genomics Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Simon V; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Center for Vaccine Research and Pandemic Preparedness (C-VARPP), Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Zuliani-Alvarez L; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Fontoura BMA; Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Rosenberg BR; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Krogan NJ; QBI COVID-19 Research Group (QCRG), San Francisco, CA 94158, USA; Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94158, USA; J. David Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX 78227, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pathology, Molecular, and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: .
Miorin L; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Global Health Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: .
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Źródło:
Cell host & microbe [Cell Host Microbe] 2023 Oct 11; Vol. 31 (10), pp. 1668-1684.e12. Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/virology
SARS-CoV-2*/genetics
Viral Proteins*/genetics
Viral Proteins*/metabolism
Humans ; Immunity, Innate ; Interferons/genetics ; Interferons/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Analytical Ultracentrifugation Detects Quaternary Rearrangements and Antibody-Induced Conformational Selection of the SARS-CoV-2 Spike Trimer.
Autorzy:
Guerrini G; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Mehn D; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Fumagalli F; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Gioria S; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
Pedotti M; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Simonelli L; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Bianchini F; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Robbiani DF; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Varani L; Institute for Research in Biomedicine, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland.
Calzolai L; European Commission, Joint Research Centre (JRC), 21027 Ispra, Italy.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Oct 03; Vol. 24 (19). Date of Electronic Publication: 2023 Oct 03.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/chemistry
SARS-CoV-2*/immunology
Spike Glycoprotein, Coronavirus*/chemistry
Spike Glycoprotein, Coronavirus*/immunology
Humans ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Epitopes/chemistry ; Epitopes/immunology ; Ultracentrifugation ; Protein Domains
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
SARS-COV-2 protein NSP9 promotes cytokine production by targeting TBK1.
Autorzy:
Zhang Y; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xin B; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Liu Y; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jiang W; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Han W; Biosafety Level 3 Laboratory, Fudan University, Shanghai, China.
Deng J; Key Laboratory for Experimental Teratology of Ministry of Education and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, China.
Wang P; Key Laboratory for Experimental Teratology of Ministry of Education and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, China.
Hong X; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yan D; Department of Immunology, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity & Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2023 Oct 02; Vol. 14, pp. 1211816. Date of Electronic Publication: 2023 Oct 02 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/complications
COVID-19*/genetics
COVID-19*/immunology
Cytokine Release Syndrome*/etiology
Cytokine Release Syndrome*/genetics
Cytokine Release Syndrome*/immunology
Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
SARS-CoV-2*/metabolism
Animals ; Mice ; COVID-19 Drug Treatment ; Cytokines ; Disease Models, Animal ; Immunity, Innate ; Signal Transduction ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2.
Autorzy:
Ahn H; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
Calderon BM; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Fan X; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Gao Y; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
Horgan NL; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
Jiang N; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Blohm DS; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
Hossain J; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Rayyan NWK; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
Osman SH; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Chamblee, Georgia, USA.
Lin X; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Currier M; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Steel J; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Wentworth DE; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Zhou B; COVID-19 Emergency Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.; Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Liang B; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia, USA.
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Źródło:
Journal of medical virology [J Med Virol] 2023 Oct; Vol. 95 (10), pp. e29163.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms:
Mink*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Spike Glycoprotein, Coronavirus*/metabolism
Animals ; Humans ; Angiotensin-Converting Enzyme 2/metabolism ; Carrier Proteins/metabolism ; COVID-19/veterinary ; Cryoelectron Microscopy ; Glycoproteins ; Protein Binding ; Receptors, Virus/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Sangivamycin is preferentially incorporated into viral RNA by the SARS-CoV-2 polymerase.
Autorzy:
Bennett RP; OyaGen, Inc., Rochester, NY, USA. Electronic address: .
Yoluç Y; Department of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany. Electronic address: .
Salter JD; OyaGen, Inc., Rochester, NY, USA. Electronic address: .
Ripp A; Institute of Organic Chemistry Albert-Ludwigs-University, Freiburg, Germany. Electronic address: .
Jessen HJ; Institute of Organic Chemistry Albert-Ludwigs-University, Freiburg, Germany. Electronic address: .
Kaiser SM; Department of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany. Electronic address: .
Smith HC; OyaGen, Inc., Rochester, NY, USA; Department of Biochemistry and Biophysics, Center for RNA Biology, Center for AIDS Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA. Electronic address: .
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Źródło:
Antiviral research [Antiviral Res] 2023 Oct; Vol. 218, pp. 105716. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
COVID-19*
Humans ; RNA, Viral/genetics ; RNA-Dependent RNA Polymerase/metabolism ; Antiviral Agents/chemistry
Czasopismo naukowe
Szczegóły
Tytuł:
Assessment of thermal and temporal stability of SARS-CoV-2 samples using real-time qRT-PCR.
Autorzy:
Swain RK; Department of Biological Sciences and Engineering, MANIT, Bhopal, India.
Mohanty SS; Virology Laboratory, Indian Council of Medical Research- National Institute for Implementation Research on Non-Communicable Diseases (ICMR-NIIRNCD), New Pali Road, Jodhpur, 342005, Rajasthan, India. .
Thakor M; Virology Laboratory, Indian Council of Medical Research- National Institute for Implementation Research on Non-Communicable Diseases (ICMR-NIIRNCD), New Pali Road, Jodhpur, 342005, Rajasthan, India.
Sharma AK; Virology Laboratory, Indian Council of Medical Research- National Institute for Implementation Research on Non-Communicable Diseases (ICMR-NIIRNCD), New Pali Road, Jodhpur, 342005, Rajasthan, India.
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Źródło:
Molecular biology reports [Mol Biol Rep] 2023 Oct; Vol. 50 (10), pp. 8565-8573. Date of Electronic Publication: 2023 Aug 29.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/diagnosis
COVID-19*/genetics
COVID-19*/physiopathology
COVID-19*/virology
COVID-19 Testing*/methods
COVID-19 Testing*/standards
Real-Time Polymerase Chain Reaction*
SARS-CoV-2*/genetics
SARS-CoV-2*/physiology
Specimen Handling*/methods
Specimen Handling*/standards
Humans ; Asian People ; RNA-Dependent RNA Polymerase
Czasopismo naukowe
Szczegóły
Tytuł:
Protracted course of SARS-CoV-2 pneumonia in moderately to severely immunocompromised patients.
Autorzy:
Lee J; Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kim AR; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kang SW; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Chang E; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Bae S; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Jung J; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kim MJ; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Chong YP; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Lee SO; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Choi SH; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kim YS; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea.
Kim SH; Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro-43-gil, Songpa-gu, Seoul, 05505, South Korea. .
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Źródło:
Clinical and experimental medicine [Clin Exp Med] 2023 Oct; Vol. 23 (6), pp. 2255-2264. Date of Electronic Publication: 2023 Jan 06.
Typ publikacji:
Review; Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*
United States ; Adult ; Humans ; COVID-19 Vaccines ; Immunocompromised Host ; Tertiary Care Centers
Czasopismo naukowe
Szczegóły
Tytuł:
Emergence of SARS-CoV-2 Delta Variant and Effect of Nonpharmaceutical Interventions, British Columbia, Canada.
Autorzy:
Chan YLE
Irvine MA
Prystajecky N
Sbihi H
Taylor M
Joffres Y
Schertzer A
Rose C
Dyson L
Hill EM
Tildesley M
Tyson JR
Hoang LMN
Galanis E
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Źródło:
Emerging infectious diseases [Emerg Infect Dis] 2023 Oct; Vol. 29 (10), pp. 1999-2007. Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/epidemiology
COVID-19*/prevention & control
Humans ; British Columbia/epidemiology ; Retrospective Studies
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Dauricine interferes with SARS-CoV-2 variants infection by blocking the interface between RBD and ACE2.
Autorzy:
Xie L; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.
Shi S; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.
Cheng L; Institute for Hepatology, Shenzhen Third People's Hospital, Shenzhen 518112, China.
Xu B; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.
Ma S; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.
Liu J; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China.
Wu X; Center for Public Health Research, Medical School, Nanjing University, Nanjing, 210023, China. Electronic address: .
Wang Y; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China. Electronic address: .
Ye S; Frontiers Science Center for Synthetic Biology (Ministry of Education), Tianjin Key Laboratory of Function and Application of Biological Macromolecular Structures, School of Life Sciences, Tianjin University, Tianjin 300072, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 7), pp. 127344. Date of Electronic Publication: 2023 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*
Humans ; Angiotensin-Converting Enzyme 2/genetics ; Antiviral Agents/pharmacology ; Protein Binding
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Tytuł:
Discovery of druggable potent inhibitors of serine proteases and farnesoid X receptor by ligand-based virtual screening to obstruct SARS-CoV-2.
Autorzy:
Zaib S; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan. Electronic address: .
Rana N; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
Ali HS; INEOS Oxford Institute for Antimicrobial Research and Chemistry Research Laboratory, Department of Chemistry, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.
Hussain N; Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, Al Ain, P.O. Box 64141, United Arab Emirates; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, P.O. Box 144534, United Arab Emirates.
Areeba; Department of Basic and Applied Chemistry, Faculty of Science and Technology, University of Central Punjab, Lahore 54590, Pakistan.
Ogaly HA; Chemistry Department, College of Science, King Khalid University, Abha 61421, Saudi Arabia.
Al-Zahrani FAM; Chemistry Department, College of Science, King Khalid University, Abha 61421, Saudi Arabia.
Khan I; Department of Chemistry and Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester M1 7DN, United Kingdom. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 7), pp. 127379. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*
Animals ; Humans ; Serine Proteases ; Furin ; Cathepsin B ; Ligands ; Pandemics ; Virus Internalization ; Mammals
Czasopismo naukowe
Szczegóły
Tytuł:
An engineered bispecific nanobody in tetrameric secretory IgA format confers broad neutralization against SARS-CoV-1&2 and most variants.
Autorzy:
Zeng W; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.
Jia X; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430062, China.
Chi X; Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Zhang X; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430062, China.
Li E; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.
Wu Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430062, China.
Liu Y; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430062, China.
Han J; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China.
Ni K; Department of Chemical Physics, University of Science and Technology of China, Hefei, Anhui 230026, China.
Ye X; Department of Chemical Physics, University of Science and Technology of China, Hefei, Anhui 230026, China.
Hu X; Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.
Ma H; Institute of Clinical Immunology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China. Electronic address: .
Yu C; Institute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China. Electronic address: .
Chiu S; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China. Electronic address: .
Jin T; Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230027, China; Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, Anhui, China. Electronic address: .
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Źródło:
International journal of biological macromolecules [Int J Biol Macromol] 2023 Dec 31; Vol. 253 (Pt 3), pp. 126817. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
Antibodies*
Animals ; Cricetinae ; Mice ; Disease Outbreaks ; Immunoglobulin A, Secretory ; RNA, Viral ; Antibodies, Viral ; Antibodies, Neutralizing
Czasopismo naukowe
Szczegóły
Tytuł:
SARS-CoV-2 S-RBD IgG & Neutralizing antibodies among different categories of health care workers post third dose BNT162b2 mRNA COVID-19 vaccine.
Autorzy:
Wan Shuaib WMA; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Badaruddin IA; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Mansor M; Department of Laboratory Diagnostic Services (JPMD), Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Salleh SA; Department of Medical Microbiology & Immunology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Hassan MR; Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Lindong S; Department of Laboratory Diagnostic Services (JPMD), Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Samad SN; Department of Laboratory Diagnostic Services (JPMD), Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
Othman H; Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Hospital Canselor Tuanku Muhriz, UKMMC, Kuala Lumpur, Malaysia.
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Źródło:
Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2023 Dec 15; Vol. 19 (3), pp. 2266931. Date of Electronic Publication: 2023 Oct 13.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*/prevention & control
Humans ; Male ; BNT162 Vaccine ; COVID-19 Vaccines ; Antibodies, Neutralizing ; Breakthrough Infections ; Health Personnel ; RNA, Messenger ; Immunoglobulin G ; Antibodies, Viral
Czasopismo naukowe
Szczegóły
Tytuł:
Mechanistic and thermodynamic characterization of antiviral inhibitors targeting nucleocapsid N-terminal domain of SARS-CoV-2.
Autorzy:
Dhaka P; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Singh A; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Choudhary S; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Peddinti RK; Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Kumar P; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. Electronic address: .
Sharma GK; Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, 243122, India. Electronic address: .
Tomar S; Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India. Electronic address: .
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Źródło:
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2023 Dec; Vol. 750, pp. 109820. Date of Electronic Publication: 2023 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*
Humans ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Post-Acute COVID-19 Syndrome ; Nucleocapsid/metabolism ; Thermodynamics ; RNA ; Molecular Docking Simulation
Czasopismo naukowe
Szczegóły
Tytuł:
Low level of tonic interferon signalling is associated with enhanced susceptibility to SARS-CoV-2 variants of concern in human lung organoids.
Autorzy:
Flagg M; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Goldin K; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Pérez-Pérez L; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Singh M; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Williamson BN; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
Pruett N; Thoracic Surgery Branch, Division of Intramural Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hoang CD; Thoracic Surgery Branch, Division of Intramural Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
de Wit E; Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2023 Dec; Vol. 12 (2), pp. 2276338. Date of Electronic Publication: 2023 Nov 16.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*
Humans ; Organoids ; Interferons/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 354048

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