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Wyszukujesz frazę ""SARS-CoV-2"" wg kryterium: Temat


Tytuł:
Confirmation of radiant catalytic ionization efficacy for airborne SARS-CoV-2 elimination indoors using "COVID19 traps".
Autorzy:
Orenes-Piñero E; Proteomic Unit, Instituto Murciano de Investigaciones Biosanitarias (IMIB_Pascual Parrilla), Murcia, Spain. Electronic address: .
Moreno-Docón A; Department of Virology, Hospital Clínico Universitario Virgen de la Arrixaca (HCUVA), Murcia, Spain.
Candela-González J; Department of Biochemistry and Molecular Biology-A, University of Murcia, Murcia, Spain.
Navas-Carrillo D; Department of Surgery, HCUVA, University of Murcia, Murcia, Spain.
Ortega-García JA; Environment and Human Health (EH2) Lab IMIB-Pascual Parrilla, Pediatric Environmental Health, HCUVA, Murcia, Spain.
Ramírez P; Department of Surgery, HCUVA, University of Murcia, Murcia, Spain.
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Źródło:
Journal of infection and public health [J Infect Public Health] 2022 Dec; Vol. 15 (12), pp. 1551-1554. Date of Electronic Publication: 2022 Nov 21.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*/prevention & control
Humans ; Longitudinal Studies ; Technology ; Viral Load
Czasopismo naukowe
Tytuł:
Acriflavine and proflavine hemisulfate as potential antivirals by targeting Mpro.
Autorzy:
Liang J; Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
Zheng M; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Xu W; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Chen Y; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai 200032, China.
Tang P; Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
Wu G; Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China. Electronic address: .
Zou P; Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China. Electronic address: .
Li H; Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China; Institute of Structural Pharmacology & TCM Chemical Biology, College of Pharmacy, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China; School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China. Electronic address: li_.
Chen L; Wuya College of Innovation, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: .
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Źródło:
Bioorganic chemistry [Bioorg Chem] 2022 Dec; Vol. 129, pp. 106185. Date of Electronic Publication: 2022 Oct 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Acriflavine*/pharmacology
COVID-19*/drug therapy
Proflavine*/pharmacology
SARS-CoV-2*/drug effects
SARS-CoV-2*/enzymology
Coronavirus 3C Proteases*/antagonists & inhibitors
Cysteine Proteinase Inhibitors*/pharmacology
Viral Protease Inhibitors*/pharmacology
Mesocricetus ; Animals ; Cricetinae ; Cell Line ; Virus Replication/drug effects
Czasopismo naukowe
Tytuł:
Reaction of 7α-bromo-6-nitrocholest-5-enes with hydrazine: Formation of steroidal pyrazolines and molecular docking against SARS-CoV-2 omicron protease.
Autorzy:
Shahabuddin; Department of Applied Chemistry, Z.H. College of Engineering & Technology, Aligarh Muslim University, Aligarh 202002, India. Electronic address: .
Kumar A; Division of Organic Synthesis, Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India.
Parveen M; Division of Organic Synthesis, Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India. Electronic address: .
Alam M; Department of Safety Engineering, Dongguk University, 123 Dongdae-ro, Gyeongju-si, Gyeongbuk 780714, South Korea. Electronic address: .
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Źródło:
Steroids [Steroids] 2022 Dec; Vol. 188, pp. 109120. Date of Electronic Publication: 2022 Oct 05.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/drug therapy
SARS-CoV-2*/enzymology
SARS-CoV-2*/metabolism
Coronavirus 3C Proteases*/antagonists & inhibitors
Humans ; Hydrazines ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Peptide Hydrolases
Czasopismo naukowe
Tytuł:
Mapping cross-variant neutralizing sites on the SARS-CoV-2 spike protein.
Autorzy:
Xu S; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Wang Y; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Wang Y; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Zhang C; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Hong Q; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Gu C; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Xu R; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Wang T; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Yang Y; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Zang J; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Zhou Y; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Li Z; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Liu Q; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Zhou B; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Bai L; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Zhu Y; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.; BSL-3 Laboratory of Fudan University, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Deng Q; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Wang H; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Lavillette D; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Wong G; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Xie Y; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.; BSL-3 Laboratory of Fudan University, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China.
Cong Y; State Key Laboratory of Molecular Biology, National Center for Protein Science Shanghai, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
Huang Z; CAS Key Laboratory of Molecular Virology & Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, People's Republic of China.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 351-367.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19/*virology
SARS-CoV-2/*immunology
Spike Glycoprotein, Coronavirus/*chemistry
Spike Glycoprotein, Coronavirus/*immunology
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; COVID-19/immunology ; Epitope Mapping ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Neutralization Tests ; SARS-CoV-2/chemistry ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics
Czasopismo naukowe
Tytuł:
Omicron: a drug developer's perspective.
Autorzy:
Fang FF; Abimmune Biopharma, Inc., San Diego, CA, USA.
Shi PY; Department of Biochemistry and Molecular Biology, Department of Biochemistry and Molecular Biology, The University of Texas Medical Branch, Galveston, TX, USA.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 208-211.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2/*metabolism
COVID-19/*drug therapy
Drug Design/*methods
Receptors, Virus/*metabolism
SARS-CoV-2/*genetics
Spike Glycoprotein, Coronavirus/*genetics
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/immunology ; Antiviral Agents/chemical synthesis ; Antiviral Agents/therapeutic use ; Binding Sites ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; COVID-19 Vaccines/administration & dosage ; COVID-19 Vaccines/adverse effects ; Humans ; Immune Evasion ; Mutation ; Protein Binding ; Receptors, Virus/genetics ; Receptors, Virus/immunology ; SARS-CoV-2/drug effects ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/immunology ; Spike Glycoprotein, Coronavirus/metabolism
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model.
Autorzy:
Chen Y; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Li C; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.
Liu F; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Ye Z; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Song W; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.
Lee ACY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.
Shuai H; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Lu L; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
To KK; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
Chan JF; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.; Academician Workstation of Hainan Province and Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Hainan Medical University, Haikou, People's Republic of China.
Zhang AJ; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.
Chu H; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.
Yuen KY; State Key Laboratory of Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Department of Microbiology, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Sha Tin, Hong Kong Special Administrative Region, People's Republic of China.; Department of Clinical Microbiology and Infection Control, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People's Republic of China.; Academician Workstation of Hainan Province and Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Hainan Medical University, Haikou, People's Republic of China.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 368-383.
Typ publikacji:
Journal Article
MeSH Terms:
Age Factors*
COVID-19/*immunology
COVID-19 Vaccines/*immunology
SARS-CoV-2/*immunology
Aging/immunology ; Animals ; Antibodies, Viral/immunology ; COVID-19/pathology ; COVID-19/prevention & control ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; Disease Models, Animal ; Disease Susceptibility ; Female ; Humans ; Immunity ; Mice ; Mice, Inbred C57BL ; Respiratory System/immunology ; Respiratory System/virology ; SARS-CoV-2/genetics ; SARS-CoV-2/physiology ; Vaccination ; Virus Replication
SCR Disease Name:
COVID-19 breakthrough infections
Czasopismo naukowe
Tytuł:
A second functional furin site in the SARS-CoV-2 spike protein.
Autorzy:
Zhang Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.; National Vaccine & Serum Institute, Beijing, People's Republic of China.
Zhang L; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wu J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Yu Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Liu S; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Li T; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Li Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Ding R; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wang H; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Nie J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Cui Z; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wang Y; National Vaccine & Serum Institute, Beijing, People's Republic of China.
Huang W; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wang Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.; Lead Contact.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 182-194.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2/*metabolism
Cathepsin L/*metabolism
Furin/*metabolism
SARS-CoV-2/*genetics
Serine Endopeptidases/*metabolism
Spike Glycoprotein, Coronavirus/*genetics
Amino Acid Sequence ; Angiotensin-Converting Enzyme 2/genetics ; Animals ; Cathepsin L/genetics ; Cell Fusion ; Chiroptera ; Furin/genetics ; Gene Expression ; HEK293 Cells ; Humans ; Mice ; Mice, Transgenic ; Mutation ; Receptors, Virus/genetics ; Receptors, Virus/metabolism ; SARS-CoV-2/growth & development ; SARS-CoV-2/metabolism ; SARS-CoV-2/pathogenicity ; Serine Endopeptidases/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Vermilingua
Czasopismo naukowe
Tytuł:
The significant immune escape of pseudotyped SARS-CoV-2 variant Omicron.
Autorzy:
Zhang L; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Li Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.; Jiangsu Recbio Technology Co., Ltd., Taizhou, People's Republic of China.
Liang Z; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.; Graduate School of Peking Union Medical College, Beijing, People's Republic of China.
Li T; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Liu S; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Cui Q; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Nie J; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wu Q; Translational Medicine Institute, The First People's Hospital of Chenzhou, University of South China, Chenzhou, People's Republic of China.
Qu X; Translational Medicine Institute, The First People's Hospital of Chenzhou, University of South China, Chenzhou, People's Republic of China.
Huang W; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
Wang Y; Division of HIV/AIDS and Sex-transmitted Virus Vaccines, Institute for Biological Product Control, National Institutes for Food and Drug Control (NIFDC), Beijing, People's Republic of China.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 1-5.
Typ publikacji:
Journal Article
MeSH Terms:
Immune Evasion*
Viral Pseudotyping*
COVID-19/*immunology
COVID-19/*virology
Host-Pathogen Interactions/*immunology
SARS-CoV-2/*immunology
Humans ; Mutation ; SARS-CoV-2/classification ; SARS-CoV-2/genetics ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Computational investigation of potent inhibitors against SARS-CoV-2 2'-O-methyltransferase (nsp16): Structure-based pharmacophore modeling, molecular docking, molecular dynamics simulations and binding free energy calculations.
Autorzy:
Shi L; The School of Life Science and Biotechnology, Dalian University, Dalian, 116622, PR China.
Wen Z; The School of Life Science and Biotechnology, Dalian University, Dalian, 116622, PR China.
Song Y; The School of Life Science and Biotechnology, Dalian University, Dalian, 116622, PR China.
Wang J; Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang, 110016, PR China. Electronic address: .
Yu D; The School of Life Science and Biotechnology, Dalian University, Dalian, 116622, PR China. Electronic address: .
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Źródło:
Journal of molecular graphics & modelling [J Mol Graph Model] 2022 Dec; Vol. 117, pp. 108306. Date of Electronic Publication: 2022 Aug 18.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/drug therapy
SARS-CoV-2*
Amino Acids ; Humans ; Methyltransferases ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; RNA, Viral ; Viral Nonstructural Proteins/chemistry
Czasopismo naukowe
Tytuł:
A year living with SARS-CoV-2: an epidemiological overview of viral lineage circulation by whole-genome sequencing in Barcelona city (Catalonia, Spain).
Autorzy:
Andrés C; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Piñana M; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Borràs-Bermejo B; Preventive Medicine and Epidemiology Department, Vall d´Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
González-Sánchez A; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
García-Cehic D; Liver Diseases-Viral Hepatitis, Liver Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Esperalba J; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Rando A; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Zules-Oña RG; Preventive Medicine and Epidemiology Department, Vall d´Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Campos C; Liver Diseases-Viral Hepatitis, Liver Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Codina MG; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Blanco-Grau A; Clinical Biochemistry (Clinical Laboratories), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Colomer-Castell S; Liver Diseases-Viral Hepatitis, Liver Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Martín MC; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Castillo C; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
García-Comuñas K; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Vásquez-Mercado R; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Martins-Martins R; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Saubi N; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron, Barcelona, Spain.
Campins-Martí M; Preventive Medicine and Epidemiology Department, Vall d´Hebron Research Institute (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.
Pumarola T; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
Quer J; Liver Diseases-Viral Hepatitis, Liver Unit, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain.
Antón A; Respiratory Viruses Unit, Microbiology Department, Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Barcelona Hospital Campus Barcelona, Spain.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 172-181.
Typ publikacji:
Journal Article
MeSH Terms:
Genome, Viral*
Mutation*
COVID-19/*epidemiology
SARS-CoV-2/*classification
SARS-CoV-2/*genetics
Spike Glycoprotein, Coronavirus/*genetics
Adolescent ; Adult ; Aged ; COVID-19/prevention & control ; COVID-19/transmission ; COVID-19/virology ; COVID-19 Vaccines/administration & dosage ; Child ; Child, Preschool ; Computational Biology/methods ; Epidemiological Monitoring ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Nasopharynx/virology ; Physical Distancing ; Prevalence ; SARS-CoV-2/pathogenicity ; Spain/epidemiology ; Vaccination/methods ; Whole Genome Sequencing
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Infection and transmission of ancestral SARS-CoV-2 and its alpha variant in pregnant white-tailed deer.
Autorzy:
Cool K; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Gaudreault NN; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Morozov I; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Trujillo JD; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Meekins DA; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
McDowell C; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Carossino M; Louisiana Animal Disease Diagnostic Laboratory and Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA.
Bold D; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Mitzel D; United States Department of Agriculture, Foreign Arthropod-Borne Animal Disease Research Unit, National Bio and Agro-Defense Facility, Manhattan, KS, USA.
Kwon T; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Balaraman V; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Madden DW; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Artiaga BL; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Pogranichniy RM; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Roman-Sosa G; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Henningson J; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
Wilson WC; United States Department of Agriculture, Foreign Arthropod-Borne Animal Disease Research Unit, National Bio and Agro-Defense Facility, Manhattan, KS, USA.
Balasuriya UBR; Louisiana Animal Disease Diagnostic Laboratory and Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA.
García-Sastre A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Richt JA; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA.
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Źródło:
Emerging microbes & infections [Emerg Microbes Infect] 2022 Dec; Vol. 11 (1), pp. 95-112.
Typ publikacji:
Journal Article
MeSH Terms:
Deer*
Pregnancy Complications, Infectious*
SARS-CoV-2*/classification
SARS-CoV-2*/genetics
SARS-CoV-2*/immunology
Animal Diseases/*epidemiology
Animal Diseases/*transmission
Animal Diseases/*virology
COVID-19/*veterinary
Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Cell Line ; Disease Susceptibility ; Enzyme-Linked Immunosorbent Assay ; Female ; High-Throughput Nucleotide Sequencing ; Organ Specificity ; Pregnancy ; RNA, Viral ; Virus Shedding
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics.
Autorzy:
Chauhan D; Tata Institute for Genetics and Society, Centre at inStem, Bangalore 560065, India.
Chakravarty N; Department of Epidemiology, University of California, Los Angeles, CA 90095, USA.
Jeyachandran AV; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.
Jayakarunakaran A; Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA.
Sinha S; All India Institute of Medical Sciences, New Delhi 110029, India.
Mishra R; Tata Institute for Genetics and Society, Centre at inStem, Bangalore 560065, India.
Arumugaswami V; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095, USA.
Ramaiah A; Tata Institute for Genetics and Society, Centre at inStem, Bangalore 560065, India.
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Źródło:
Viruses [Viruses] 2022 Nov 06; Vol. 14 (11). Date of Electronic Publication: 2022 Nov 06.
Typ publikacji:
Journal Article
MeSH Terms:
Antiviral Agents*/pharmacology
Antiviral Agents*/therapeutic use
COVID-19*/immunology
COVID-19*/virology
Immune Evasion*
SARS-CoV-2*/drug effects
SARS-CoV-2*/genetics
Humans ; Mutation ; Phylogeny ; Spike Glycoprotein, Coronavirus/genetics ; Viral Envelope Proteins/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
In Silico Approach for the Evaluation of the Potential Antiviral Activity of Extra Virgin Olive Oil (EVOO) Bioactive Constituents Oleuropein and Oleocanthal on Spike Therapeutic Drug Target of SARS-CoV-2.
Autorzy:
Geromichalou EG; Laboratory of Pharmacology, Medical School, National and Kapodistrian University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece.
Geromichalos GD; Department of General and Inorganic Chemistry, Faculty of Chemistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2022 Nov 04; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 04.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*/drug therapy
Humans ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry ; Spike Glycoprotein, Coronavirus/metabolism ; Olive Oil ; Molecular Docking Simulation ; Peptidyl-Dipeptidase A/metabolism ; Binding Sites ; Protein Binding
Czasopismo naukowe
Tytuł:
Breakthrough infection with SARS-CoV-2 delta variant in old-age homes in a Southern District of Kerala, India.
Autorzy:
Chandran D; Junior Resident, Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India.
Sreekumar E; Director, Institute of Advanced Virology, Thiruvananthapuram, Kerala, India.
Prajitha KC; Senior Resident, Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India.
Sharahudeen A; Junior Resident, Department of Community Medicine, Government Medical College, Thiruvananthapuram, Kerala, India.
Raveendran CL; Assistant Surgeon, Department of Health Services, Kerala, India.
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Corporate Authors:
Research team
Źródło:
Indian journal of public health [Indian J Public Health] 2022 Nov; Vol. 66 (Supplement), pp. S36-S40.
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*
Aged ; Humans ; Infant, Newborn ; COVID-19 Vaccines ; Phylogeny ; India/epidemiology
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Ganoderma microsporum immunomodulatory protein acts as a multifunctional broad-spectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion.
Autorzy:
Ho HPT; Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Vo DNK; Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Lin TY; Institute of Traditional Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Research Center for Epidemic Prevention, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hung JN; Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chiu YH; Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tsai MH; Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taipei, Taiwan; Research Center for Epidemic Prevention, National Yang Ming Chiao Tung University, Taipei, Taiwan. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Nov; Vol. 155, pp. 113766. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*
COVID-19*/drug therapy
Humans ; Angiotensin-Converting Enzyme 2 ; Antiviral Agents/pharmacology ; Virus Attachment ; Receptors, Virus/metabolism ; Cell Fusion ; HEK293 Cells ; Protein Binding
SCR Organism:
SARS-CoV-2 variants; Ganoderma microsporum
Czasopismo naukowe
Tytuł:
Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: A nested case-control within the SIREN study.
Autorzy:
Atti A; UK Health Security Agency, Smith Square, London SW1P, UK. Electronic address: .
Insalata F; UK Health Security Agency, Smith Square, London SW1P, UK.
Carr EJ; The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK.
Otter AD; UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Castillo-Olivares J; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK.
Wu M; The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK.
Harvey R; The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK.
Howell M; The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK.
Chan A; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK.
Lyall J; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK.
Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, Universities of Greenwich and Kent at Medway, Central Ave, Gillingham, Chatham ME4 4BF, UK.
Cantoni D; Viral Pseudotype Unit, Medway School of Pharmacy, Universities of Greenwich and Kent at Medway, Central Ave, Gillingham, Chatham ME4 4BF, UK.
da Costa K; Viral Pseudotype Unit, Medway School of Pharmacy, Universities of Greenwich and Kent at Medway, Central Ave, Gillingham, Chatham ME4 4BF, UK.
Nadesalingam A; Laboratory of Viral Zoonotics, Department of Veterinary Medicine, University of Cambridge, Cambridge University, Madingley Road, Cambridge CB3 0ES, UK.
Taylor-Kerr A; UK Health Security Agency, Smith Square, London SW1P, UK.
Hettiarachchi N; UK Health Security Agency, Smith Square, London SW1P, UK.
Tranquillini C; UK Health Security Agency, Smith Square, London SW1P, UK.
Hewson J; UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Cole MJ; UK Health Security Agency, Smith Square, London SW1P, UK.
Foulkes S; UK Health Security Agency, Smith Square, London SW1P, UK.
Munro K; UK Health Security Agency, Smith Square, London SW1P, UK.
Monk EJM; UK Health Security Agency, Smith Square, London SW1P, UK.
Milligan ID; UK Health Security Agency, Smith Square, London SW1P, UK.
Linley E; Manchester Royal Infirmary, UK Health Security Agency, Oxford Road, Manchester M139WL, UK.
Chand MA; UK Health Security Agency, Smith Square, London SW1P, UK.
Brown CS; UK Health Security Agency, Smith Square, London SW1P, UK; The National Institute for Health Research Health Protection Research (NIHR) Unit in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford, Old Road Campus, Headington, Oxford OX3 7BN, UK.
Islam J; UK Health Security Agency, Smith Square, London SW1P, UK.
Semper A; UK Health Security Agency, Smith Square, London SW1P, UK.
Charlett A; UK Health Security Agency, Smith Square, London SW1P, UK; NIHR Health Protection Research Unit in Behavioural Science and Evaluation at University of Bristol in partnership with Public Health England, Queens Road, Bristol BS8 1QU, UK; NIHR Health Protection Research Unit in Immunisation at the London School of Hygiene and Tropical Medicine in partnership with Public Health England, Keppel St, London WC1E 7HT, UK.
Heeney JL; UK Health Security Agency, Porton Down, Salisbury SP4 0JG, UK.
Beale R; The Francis Crick Institute, 1 Midland Rd, London NW1 1AT, UK.
Zambon M; UK Health Security Agency, Smith Square, London SW1P, UK.
Hopkins S; UK Health Security Agency, Smith Square, London SW1P, UK; The National Institute for Health Research Health Protection Research (NIHR) Unit in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford, Old Road Campus, Headington, Oxford OX3 7BN, UK.
Brooks T; UK Health Security Agency, Smith Square, London SW1P, UK.
Hall V; UK Health Security Agency, Smith Square, London SW1P, UK; The National Institute for Health Research Health Protection Research (NIHR) Unit in Healthcare Associated Infections and Antimicrobial Resistance at the University of Oxford, Old Road Campus, Headington, Oxford OX3 7BN, UK.
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Corporate Authors:
SIREN Study Group and the Crick COVID Immunity Pipeline Consortium; UK Health Security Agency, Smith Square, London SW1P, UK.
Źródło:
The Journal of infection [J Infect] 2022 Nov; Vol. 85 (5), pp. 545-556. Date of Electronic Publication: 2022 Sep 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
COVID-19*/prevention & control
SARS-CoV-2*
Antibodies, Viral ; Case-Control Studies ; Humans ; Reinfection/prevention & control ; Vaccination
Czasopismo naukowe
Tytuł:
Identification and assessment of TCR-T cells targeting an epitope conserved in SARS-CoV-2 variants for the treatment of COVID-19.
Autorzy:
Ma Y; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Liu F; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Li B; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Peng K; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Zhou H; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Xu Y; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Qiao D; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Deng L; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China.
Tian G; Department of Oncology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Nielsen M; Department of Health Technology, Section for Bioinformatics, Technical University of Denmark, Lyngby, Denmark.
Wang M; Department of Research and Development, Shenzhen Institute for Innovation and Translational Medicine, Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China; Shenzhen Innovation Immunotechnology Co., Ltd. Shenzhen International Biological Valley-Life Science Industrial Park, Dapeng New District, Shenzhen, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2022 Nov; Vol. 112, pp. 109283. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji:
Journal Article
MeSH Terms:
SARS-CoV-2*/genetics
COVID-19*/therapy
Humans ; Epitopes ; Receptors, Antigen, T-Cell/genetics ; Antibodies, Monoclonal/therapeutic use ; RNA-Dependent RNA Polymerase ; Cytokines ; Epitopes, T-Lymphocyte/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Differential avidity determination of IgG directed towards the receptor-binding domain (RBD) of SARS-CoV-2 wild-type and its variants in one assay: Rational tool for the assessment of protective immunity.
Autorzy:
Bauer G; Institute of Virology, Medical Center, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Struck F; Mikrogen GmbH, Neuried, Germany.
Staschik E; Mikrogen GmbH, Neuried, Germany.
Maile J; Mikrogen GmbH, Neuried, Germany.
Wochinz-Richter K; Mikrogen GmbH, Neuried, Germany.
Motz M; Mikrogen GmbH, Neuried, Germany.
Soutschek E; Mikrogen GmbH, Neuried, Germany.
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Źródło:
Journal of medical virology [J Med Virol] 2022 Nov; Vol. 94 (11), pp. 5294-5303. Date of Electronic Publication: 2022 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/diagnosis
SARS-CoV-2*/genetics
Antibodies, Viral ; Humans ; Immunoglobulin G ; Spike Glycoprotein, Coronavirus/genetics
SCR Organism:
SARS-CoV-2 variants
Czasopismo naukowe
Tytuł:
Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detection.
Autorzy:
Fujiya Y; Department of Infection Control and Laboratory Medicine, Sapporo Medical University School of Medicine, Japan. Electronic address: .
Sato Y; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Katayama Y; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Nirasawa S; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Moriai M; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Saeki M; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Yakuwa Y; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Kitayama I; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Asanuma K; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan.
Kuronuma K; Division of Infection Control, Sapporo Medical University Hospital, Japan; Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Japan.
Takahashi S; Department of Infection Control and Laboratory Medicine, Sapporo Medical University School of Medicine, Japan; Division of Laboratory Medicine, Sapporo Medical University Hospital, Japan; Division of Infection Control, Sapporo Medical University Hospital, Japan.
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Źródło:
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy [J Infect Chemother] 2022 Nov; Vol. 28 (11), pp. 1590-1593. Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
COVID-19*/diagnosis
SARS-CoV-2*/genetics
COVID-19 Testing ; Humans ; Nasopharynx ; Nucleic Acid Amplification Techniques ; Sensitivity and Specificity ; Serologic Tests ; Viral Load
Czasopismo naukowe

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