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Starter badań:

Tytuł:
Knockdown and inhibition of hydroxytryptamine receptor 1D suppress proliferation and migration of gastric cancer cells.
Autorzy:
Jin X; Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518107, China.
Li H; Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518107, China.
Li B; Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518107, China.
Zhang C; Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518107, China. Electronic address: .
He Y; Digestive Diseases Center, The Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, Guangdong, 518107, China; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 510080, China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Sep 10; Vol. 620, pp. 143-149. Date of Electronic Publication: 2022 Jun 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Serotonin*
Stomach Neoplasms*/pathology
Receptor, Serotonin, 5-HT1D/*metabolism
Cell Line, Tumor ; Cell Movement ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Humans ; Receptor, Serotonin, 5-HT1D/genetics ; Receptors, Serotonin/genetics ; Receptors, Serotonin/metabolism ; Serotonin 5-HT1 Receptor Antagonists
Czasopismo naukowe
Tytuł:
Serotonin Receptor 5-HT 2A Regulates TrkB Receptor Function in Heteroreceptor Complexes.
Autorzy:
Ilchibaeva T; Cellular Neurophysiology, Center of Physiology, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.; Laboratory of Behavioral Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Prospekt Lavrentyeva 10, 630090 Novosibirsk, Russia.
Tsybko A; Laboratory of Behavioral Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Prospekt Lavrentyeva 10, 630090 Novosibirsk, Russia.
Zeug A; Cellular Neurophysiology, Center of Physiology, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.
Müller FE; Cellular Neurophysiology, Center of Physiology, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.
Guseva D; Department of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Bischoff S; Department of Nutritional Medicine, University of Hohenheim, Fruwirthstr. 12, 70599 Stuttgart, Germany.
Ponimaskin E; Cellular Neurophysiology, Center of Physiology, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.
Naumenko V; Laboratory of Behavioral Neurogenomics, Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Prospekt Lavrentyeva 10, 630090 Novosibirsk, Russia.
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Źródło:
Cells [Cells] 2022 Aug 02; Vol. 11 (15). Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin*/metabolism
Serotonin*/pharmacology
Receptor, Serotonin, 5-HT2A/*metabolism
Receptor, trkB/*metabolism
Animals ; Ketanserin ; Mice ; Receptors, Serotonin ; Tropomyosin
Czasopismo naukowe
Tytuł:
Disrupted serotonin system development via early life antidepressant exposure impairs maternal care and increases serotonin receptor expression in adult female offspring.
Autorzy:
Unroe KA; School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.; Graduate Program in Translational Biology, Medicine, and Health, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Maltman JL; School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Shupe EA; School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.; Neuroscience Graduate Program, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Clinton SM; School of Neuroscience, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
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Źródło:
Developmental psychobiology [Dev Psychobiol] 2022 Sep; Vol. 64 (6), pp. e22292.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Prenatal Exposure Delayed Effects*
Serotonin*/metabolism
Animals ; Antidepressive Agents ; Female ; Male ; Pregnancy ; Rats ; Rats, Sprague-Dawley ; Receptors, Serotonin ; Serotonin Uptake Inhibitors/pharmacology
Czasopismo naukowe
Tytuł:
Faster Serotonin Clearance in CA3 Region of Hippocampus and Antidepressant-like Effect of Decynium-22 in Juvenile Mice Are Putatively Linked to Increased Plasma Membrane Monoamine Transporter Function: Implications for Efficacy of Antidepressants in Juveniles.
Autorzy:
Bowman MA; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Gomez JA; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Mitchell NC; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Wells AM; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Vitela M; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Clarke KM; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Horton RE; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.
Koek W; Department of Cell Systems and Anatomy, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.
Daws LC; Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, MC7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA.; Department of Pharmacology, University of Texas Health Science Center, San Antonio, TX 78229-3900, USA.
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Źródło:
Cells [Cells] 2022 Aug 08; Vol. 11 (15). Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Antidepressive Agents*/pharmacology
Antidepressive Agents*/therapeutic use
Serotonin*/metabolism
Animals ; Cell Membrane/metabolism ; Hippocampus/metabolism ; Mice ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Serotonin Uptake Inhibitors/pharmacology
Czasopismo naukowe
Tytuł:
Antidepressant-induced serotonin syndrome in older patients: a cross-sectional study.
Autorzy:
Erken N; Department of Geriatric Medicine, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey.
Kaya D; Unit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.; Geriatric Science Association, Izmir, Turkey.
Dost FS; Unit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.; Geriatric Science Association, Izmir, Turkey.
Ates Bulut E; Geriatric Science Association, Izmir, Turkey.; Department of Geriatric Medicine, Adana Numune Training and Research Hospital, Adana, Turkey.
Isik AT; Unit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.; Geriatric Science Association, Izmir, Turkey.
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Źródło:
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society [Psychogeriatrics] 2022 Jul; Vol. 22 (4), pp. 502-508. Date of Electronic Publication: 2022 May 13.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin Syndrome*/chemically induced
Serotonin Syndrome*/diagnosis
Serotonin Syndrome*/drug therapy
Aged ; Aged, 80 and over ; Antidepressive Agents/adverse effects ; Benzodiazepines ; Cross-Sectional Studies ; Female ; Humans ; Male ; Serotonin Uptake Inhibitors/adverse effects
Czasopismo naukowe
Tytuł:
Serotonin 5-HT 1A and 5-HT 1B receptor-mediated inhibition of glutamatergic transmission onto rat basal forebrain cholinergic neurones.
Autorzy:
Nishijo T; Department of Pharmacology, Jikei University School of Medicine, Tokyo, Japan.; Department of Molecular Neurobiology, Institute for Developmental Research, Aichi Developmental Disability Center, Kasugai, Aichi, Japan.
Suzuki E; Department of Pharmacology, Jikei University School of Medicine, Tokyo, Japan.
Momiyama T; Department of Pharmacology, Jikei University School of Medicine, Tokyo, Japan.
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Źródło:
The Journal of physiology [J Physiol] 2022 Jul; Vol. 600 (13), pp. 3149-3167. Date of Electronic Publication: 2022 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Basal Forebrain*
Serotonin*/physiology
Animals ; Cholinergic Agents/pharmacology ; Cholinergic Neurons ; Glutamic Acid/pharmacology ; Rats ; Receptor, Serotonin, 5-HT1A ; Receptor, Serotonin, 5-HT1B ; Serotonin Receptor Agonists/pharmacology ; Synaptic Transmission/physiology
Czasopismo naukowe
Tytuł:
Novel difluoromethyl-containing 1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole scaffold as potent 5-HT 6 R antagonists: Design, synthesis, biological evaluation, and early in vivo cognition-enhancing studies.
Autorzy:
Yi C; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Xue Y; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Chen K; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Wang T; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Yu J; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Wang Z; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China.
Jin C; HEC Pharm Group, HEC Research and Development Center, Dongguan 523871, China; Sunshine Lake Pharma Co. Ltd., Shenzhen 518000, China. Electronic address: .
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Źródło:
Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Sep 15; Vol. 70, pp. 116917. Date of Electronic Publication: 2022 Jul 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, Serotonin*/metabolism
Serotonin*
Animals ; Cognition ; Indoles/pharmacology ; Piperazine ; Rats ; Serotonin Antagonists/pharmacology ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł:
Improvement of urethral dysfunction by 5-HT 1A  receptor agonist NLX-112 in diabetic rats.
Autorzy:
Li M; Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Chen X; Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Cao N; Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Lv R; Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Gu B; Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
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Źródło:
Neurourology and urodynamics [Neurourol Urodyn] 2022 Sep; Vol. 41 (7), pp. 1528-1538. Date of Electronic Publication: 2022 Jul 23.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Experimental*/chemically induced
Diabetes Mellitus, Experimental*/complications
Diabetes Mellitus, Type 1*/chemically induced
Diabetes Mellitus, Type 1*/complications
Piperidines*/pharmacology
Pyridines*/pharmacology
Serotonin 5-HT1 Receptor Antagonists*/pharmacology
Urethra*/physiopathology
Animals ; Female ; Maleates ; Rats ; Rats, Sprague-Dawley ; Receptor, Serotonin, 5-HT1A ; Serotonin ; Streptozocin
Czasopismo naukowe
Tytuł:
A Novel Antibody Targeting the Second Extracellular Loop of the Serotonin 5-HT2A Receptor Inhibits Platelet Function.
Autorzy:
Ramirez JEM; Department of Pharmaceutical Sciences, School of Pharmacy, The University of Texas El Paso, El Paso, TX 79902, USA.
Alarabi AB; Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, TX 78363, USA.
Khasawneh FT; Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, TX 78363, USA.
Alshbool FZ; Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M University, Kingsville, TX 78363, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 08; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin*/metabolism
Serotonin*/pharmacology
Thrombosis*/drug therapy
Thrombosis*/metabolism
Animals ; Antibodies/metabolism ; Blood Platelets/metabolism ; Hemostasis ; Humans ; Ligands ; Mice ; Mice, Inbred C57BL ; Platelet Aggregation ; Platelet Aggregation Inhibitors/therapeutic use ; Receptor, Serotonin, 5-HT2A/metabolism
Czasopismo naukowe
Tytuł:
The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference.
Autorzy:
Popova NK; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Tsybko AS; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
Naumenko VS; The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090, Russia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 08; Vol. 23 (15). Date of Electronic Publication: 2022 Aug 08.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Serotonin*/physiology
Suicide*
Aggression/physiology ; Depression ; Humans ; Receptors, Serotonin/genetics
Czasopismo naukowe
Tytuł:
Intestinal serotonergic system is modulated by Toll-like receptor 9.
Autorzy:
Layunta E; Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden.; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Latorre E; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain. .; Instituto Agroalimentario de Aragón - IA2- (Universidad de Zaragoza - CITA), Zaragoza, Spain. .; Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Ciencias, Universidad de Zaragoza, Pedro Cerbuna 12, 50009, Zaragoza, Spain. .
Grasa L; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.; Instituto Agroalimentario de Aragón - IA2- (Universidad de Zaragoza - CITA), Zaragoza, Spain.; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
Arruebo MP; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.; Instituto Agroalimentario de Aragón - IA2- (Universidad de Zaragoza - CITA), Zaragoza, Spain.; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
Buey B; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
Alcalde AI; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
Mesonero JE; Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.; Instituto Agroalimentario de Aragón - IA2- (Universidad de Zaragoza - CITA), Zaragoza, Spain.; Departamento de Farmacología, Fisiología y Medicina Legal y Forense, Facultad de Veterinaria, Universidad de Zaragoza, Zaragoza, Spain.
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Źródło:
Journal of physiology and biochemistry [J Physiol Biochem] 2022 Aug; Vol. 78 (3), pp. 689-701. Date of Electronic Publication: 2022 Jun 07.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin Plasma Membrane Transport Proteins*/genetics
Serotonin Plasma Membrane Transport Proteins*/metabolism
Toll-Like Receptor 9/*metabolism
Animals ; Caco-2 Cells ; Humans ; Intestines ; Mice ; Serotonin/metabolism ; Toll-Like Receptor 9/genetics
Czasopismo naukowe
Tytuł:
GPCRs steer G i and G s selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.
Autorzy:
Huang S; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Xu P; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Shen DD; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou 311121, China; MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Simon IA; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark; SARomics Biostructures AB, Scheelevägen 2, 223 63 Lund, Sweden; Present address: Vrije Universiteit Amsterdam, Division of Medicinal Chemistry, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Faculty of Science, De Boelelaan 1108, 1081 HZ Amsterdam, Netherlands.
Mao C; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou 311121, China; MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Tan Y; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhang H; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou 311121, China; MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Harpsøe K; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Li H; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Zhang Y; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
You C; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Yu X; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Jiang Y; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Zhang Y; Department of Biophysics and Department of Pathology of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China; Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou 311121, China; MOE Frontier Science Center for Brain Research and Brain-Machine Integration, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China; Key Laboratory of Immunity and Inflammatory Diseases of Zhejiang Province, Hangzhou 310058, China. Electronic address: zhang_.
Gloriam DE; Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark. Electronic address: .
Xu HE; The CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China. Electronic address: .
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Źródło:
Molecular cell [Mol Cell] 2022 Jul 21; Vol. 82 (14), pp. 2681-2695.e6. Date of Electronic Publication: 2022 Jun 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, G-Protein-Coupled*/metabolism
Serotonin*
GTP-Binding Proteins/metabolism ; Ligands ; Receptors, Serotonin/genetics ; Receptors, Serotonin/metabolism
Czasopismo naukowe
Tytuł:
Methylation and expression quantitative trait locus rs6296 in the HTR1B gene is associated with susceptibility to opioid use disorder.
Autorzy:
Li Y; Department of Human Anatomy, Shaanxi University of Chinese Medicine, Xianyang, 712046, Shaanxi, China.
Lu Y; College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.; Key Laboratory of National Health Commission for Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.
Xie Q; Bioengineering College, Chongqing University, Chongqing, 400044, China.
Zeng X; School of Forensic Medicine, Kunming Medical University, Kunming, 650500, Yunnan, China.
Zhang R; Department of Psychiatry, Xi'an Mental Health Center, Xi'an, Shaanxi, 710061, China.
Dang W; Department of Psychiatry, Xi'an Mental Health Center, Xi'an, Shaanxi, 710061, China.
Zhu Y; College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.; Key Laboratory of National Health Commission for Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China.
Zhang J; College of Forensic Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China. .; Key Laboratory of National Health Commission for Forensic Science, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China. .
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2022 Aug; Vol. 239 (8), pp. 2515-2523. Date of Electronic Publication: 2022 Apr 19.
Typ publikacji:
Journal Article
MeSH Terms:
Opioid-Related Disorders*/genetics
Quantitative Trait Loci*
Receptor, Serotonin, 5-HT1B*/genetics
DNA Methylation ; Heroin ; Humans ; Polymorphism, Single Nucleotide ; Receptors, Serotonin
Czasopismo naukowe
Tytuł:
The Roles of Serotonin in Neuropsychiatric Disorders.
Autorzy:
Pourhamzeh M; Division of Neuroscience, Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
Moravej FG; Department of Biology and Anatomical Sciences, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Arabi M; Division of Neuroscience, Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.; Department of Radiology and Medical Physics, Faculty of Paramedicine, Kashan University of Medical Sciences, Kashan, Iran.
Shahriari E; Faculty of Medicine, Department of Physiology, Iran University of Medical Sciences, Tehran, Iran.
Mehrabi S; Division of Neuroscience, Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.; Faculty of Medicine, Department of Physiology, Iran University of Medical Sciences, Tehran, Iran.
Ward R; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA.
Ahadi R; Department of Anatomy, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. .
Joghataei MT; Division of Neuroscience, Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran. .; Department of Anatomy, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. .
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Źródło:
Cellular and molecular neurobiology [Cell Mol Neurobiol] 2022 Aug; Vol. 42 (6), pp. 1671-1692. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mental Disorders*/metabolism
Serotonin*/metabolism
Humans ; Receptors, Serotonin/metabolism
Czasopismo naukowe
Tytuł:
Translational PET Imaging of Spinal Cord Injury with the Serotonin Transporter Tracer [ C]AFM.
Autorzy:
Fang H; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA. .; Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. .
Rossano S; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Wang X; Cellular Neuroscience, Neurodegeneration, and Repair Program, and Departments of Neurology and Neurobiology, Yale School of Medicine, New Haven, CT, USA.
Nabulsi N; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Kelley B; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.
Fowles K; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Ropchan J; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Strittmatter SM; Cellular Neuroscience, Neurodegeneration, and Repair Program, and Departments of Neurology and Neurobiology, Yale School of Medicine, New Haven, CT, USA.
Carson RE; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Huang Y; PET Center, Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA. .
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Źródło:
Molecular imaging and biology [Mol Imaging Biol] 2022 Aug; Vol. 24 (4), pp. 560-569. Date of Electronic Publication: 2022 Jan 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Serotonin Plasma Membrane Transport Proteins*/metabolism
Spinal Cord Injuries*/diagnostic imaging
Spinal Cord Injuries*/metabolism
Animals ; Citalopram ; Humans ; Indicators and Reagents ; Positron-Emission Tomography/methods ; Rats ; Serotonin/metabolism ; Spinal Cord/diagnostic imaging ; Tissue Distribution
Czasopismo naukowe
Tytuł:
Effects of prenatal opioid and alcohol exposures on immune and serotonin factors in human placenta.
Autorzy:
Ruyak SL; College of Nursing, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America; College of Pharmacy Substance Use Research Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America. Electronic address: .
Noor S; Department of Neurosciences, University of New Mexico, Health Sciences Center, Albuquerque, NM, United States of America.
DiDomenico J; College of Pharmacy Substance Use Research Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America.
Sun MS; Department of Neurosciences, University of New Mexico, Health Sciences Center, Albuquerque, NM, United States of America.
Fernandez Oropeza AK; Department of Neurosciences, University of New Mexico, Health Sciences Center, Albuquerque, NM, United States of America.
Rodriguez DE; College of Pharmacy Substance Use Research Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America.
Marquez LE; College of Pharmacy Substance Use Research Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America.
Milligan ED; Department of Neurosciences, University of New Mexico, Health Sciences Center, Albuquerque, NM, United States of America.
Bakhireva LN; College of Pharmacy Substance Use Research Education Center, University of New Mexico Health Sciences Center, Albuquerque, NM, United States of America.
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Źródło:
Experimental neurology [Exp Neurol] 2022 Jul; Vol. 353, pp. 114057. Date of Electronic Publication: 2022 Mar 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Prenatal Exposure Delayed Effects*
Serotonin*/metabolism
Analgesics, Opioid/adverse effects ; Child ; Ethanol/adverse effects ; Female ; Humans ; Infant ; Placenta/metabolism ; Pregnancy ; Prospective Studies ; RNA, Messenger/metabolism ; Serotonin Plasma Membrane Transport Proteins/metabolism ; Toll-Like Receptor 4/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł:
Differential expression of serotonin 2B receptors in GABAergic and serotoninergic neurons of the rat and mouse dorsal raphe nucleus.
Autorzy:
Cathala A; Inserm U1215, Neurocentre Magendie, Physiopathology and therapeutic approaches of stress-related diseases, Bordeaux F-33000, France; Université de Bordeaux, Bordeaux F-33000, France. Electronic address: .
Lucas G; Université de Bordeaux, Bordeaux F-33000, France; CNRS UMR 5287, INCIA, P3TN, Bordeaux F-33000, France. Electronic address: .
López-Terrones E; Depart. de Neurociències i Terapèutica Experimental, Institut d'Investigacions Biomèdiques de Barcelona, IIBB-CSIC, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: .
Revest JM; Inserm U1215, Neurocentre Magendie, Physiopathology and therapeutic approaches of stress-related diseases, Bordeaux F-33000, France; Université de Bordeaux, Bordeaux F-33000, France. Electronic address: .
Artigas F; Depart. de Neurociències i Terapèutica Experimental, Institut d'Investigacions Biomèdiques de Barcelona, IIBB-CSIC, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: .
Spampinato U; Inserm U1215, Neurocentre Magendie, Physiopathology and therapeutic approaches of stress-related diseases, Bordeaux F-33000, France; Université de Bordeaux, Bordeaux F-33000, France. Electronic address: .
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Źródło:
Molecular and cellular neurosciences [Mol Cell Neurosci] 2022 Jul; Vol. 121, pp. 103750. Date of Electronic Publication: 2022 Jun 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dorsal Raphe Nucleus*/metabolism
Receptor, Serotonin, 5-HT2B*/metabolism
Serotonergic Neurons*/metabolism
Animals ; Mice ; Rats ; Serotonin/pharmacology
Czasopismo naukowe
Tytuł:
5-HT 2 receptor antagonism reduces human motoneuron output to antidromic activation but not to stimulation of corticospinal axons.
Autorzy:
Thorstensen JR; Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
Taylor JL; School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia, Australia.; Neuroscience Research Australia, Sydney, New South Wales, Australia.
Kavanagh JJ; Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia.
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Źródło:
The European journal of neuroscience [Eur J Neurosci] 2022 Jul; Vol. 56 (1), pp. 3674-3686. Date of Electronic Publication: 2022 Apr 27.
Typ publikacji:
Controlled Clinical Trial; Journal Article
MeSH Terms:
Motor Neurons*/physiology
Serotonin*/pharmacology
Axons/physiology ; Cyproheptadine/pharmacology ; Double-Blind Method ; Electric Stimulation ; Evoked Potentials, Motor/physiology ; Humans ; Muscle, Skeletal/physiology ; Serotonin Antagonists/pharmacology
Czasopismo naukowe
Tytuł:
C-reactive protein could predict the efficacy of SSRIs in clinical practice: A cohort study of large samples in the real world.
Autorzy:
Pan Y; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Luo R; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Zhang S; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Liu Y; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Wang Y; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Feng S; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China.
Li H; Department of psychiatry, the First Affiliated Hospital of Zhengzhou University, No. 1, Jian she East Road, Zhengzhou 450052, Henan, China. Electronic address: .
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Źródło:
Journal of affective disorders [J Affect Disord] 2022 Sep 15; Vol. 313, pp. 251-259. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji:
Journal Article
MeSH Terms:
Serotonin and Noradrenaline Reuptake Inhibitors*
Antidepressive Agents/therapeutic use ; C-Reactive Protein ; Cohort Studies ; Humans ; Serotonin Uptake Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł:
SSRI antidepressants differentially modulate serotonin reuptake and release in Drosophila.
Autorzy:
Dunham KE; Department of Chemistry, University of Virginia, Virginia, USA.
Venton BJ; Department of Chemistry, University of Virginia, Virginia, USA.
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Źródło:
Journal of neurochemistry [J Neurochem] 2022 Sep; Vol. 162 (5), pp. 404-416. Date of Electronic Publication: 2022 Jul 09.
Typ publikacji:
Journal Article
MeSH Terms:
Citalopram*/pharmacology
Serotonin Uptake Inhibitors*/pharmacology
Animals ; Antidepressive Agents/pharmacology ; Drosophila ; Drosophila melanogaster ; Fluoxetine/pharmacology ; Mammals ; Paroxetine/pharmacology ; Serotonin
Czasopismo naukowe

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