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Tytuł :
MicroRNA-146b-3p regulates the dysfunction of vascular smooth muscle cells via repressing phosphoinositide-3 kinase catalytic subunit gamma.
Autorzy :
Zhuang X; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
Gao F; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
Shi L; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
Liu W; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
Wang W; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
He X; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
Gao Y; Department of Cardiac Surgery, Dalian Municipal Center Hospital, Dalian Liaoning, China.
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Źródło :
Bioengineered [Bioengineered] 2021 Dec; Vol. 12 (1), pp. 2627-2638.
Typ publikacji :
Journal Article
MeSH Terms :
Class Ib Phosphatidylinositol 3-Kinase/*metabolism
MicroRNAs/*metabolism
Muscle, Smooth, Vascular/*pathology
Myocytes, Smooth Muscle/*metabolism
Myocytes, Smooth Muscle/*pathology
Atherosclerosis/genetics ; Atherosclerosis/pathology ; Base Sequence ; Becaplermin/pharmacology ; Cell Movement/drug effects ; Cell Movement/genetics ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Down-Regulation/drug effects ; Humans ; MicroRNAs/genetics ; Myocytes, Smooth Muscle/drug effects ; Phenotype
Czasopismo naukowe
Tytuł :
Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging.
Autorzy :
Cimmino I; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Prisco F; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Orso S; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Agognon AL; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Liguoro P; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
De Biase D; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Doti N; Institute of Biostructure and Bioimaging, National Research Council and Interuniversity Research Centre on Bioactive Peptides Naples, Naples, Italy.
Ruvo M; Institute of Biostructure and Bioimaging, National Research Council and Interuniversity Research Centre on Bioactive Peptides Naples, Naples, Italy.
Paciello O; Department of Veterinary Medicine and Animal Production, Federico II University of Naples, Naples, Italy.
Beguinot F; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Formisano P; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
Oriente F; Department of Translational Medicine, Federico II University of Naples and URT 'Genomic of Diabetes' of Institute of Experimental Endocrinology and Oncology, National Council of Research (CNR), Naples, Italy.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Nov; Vol. 35 (11), pp. e21989.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Muscle, Smooth, Vascular*/cytology
Muscle, Smooth, Vascular*/metabolism
Myocytes, Smooth Muscle*/cytology
Myocytes, Smooth Muscle*/metabolism
Aging/*metabolism
Homeodomain Proteins/*physiology
Interleukin-6/*physiology
Animals ; Apoptosis ; Cells, Cultured ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Uterine smooth muscle tumors of uncertain malignant potential (STUMP): A retrospective study in a single center.
Autorzy :
Zhang C; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China.
Gao J; Department of Obstetrics and Gynecology, Dong Cheng District First Maternal and Child Care Service Center, Beijing 100007, China.
Lu S; Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Zhang Y; Department of Pathology, Peking University People's Hospital, Beijing 100044, China.
Zhu H; Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijing 100044, China. Electronic address: .
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Źródło :
European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2021 Oct; Vol. 265, pp. 74-79. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article
MeSH Terms :
Smooth Muscle Tumor*/diagnosis
Smooth Muscle Tumor*/surgery
Uterine Myomectomy*
Uterine Neoplasms*/diagnostic imaging
Uterine Neoplasms*/surgery
Female ; Humans ; Neoplasm Recurrence, Local ; Pregnancy ; Retrospective Studies
Czasopismo naukowe
Tytuł :
Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4).
Autorzy :
Yap C; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Location Academic Medical Center, The Netherlands (C.Y., A.M., C.J.M.d.V., V.d.W.).
Mieremet A; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Location Academic Medical Center, The Netherlands (C.Y., A.M., C.J.M.d.V., V.d.W.).
de Vries CJM; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Location Academic Medical Center, The Netherlands (C.Y., A.M., C.J.M.d.V., V.d.W.).
Micha D; Department of Clinical Genetics, Amsterdam Cardiovascular Sciences, Vrije Universiteit Amsterdam, Amsterdam UMC, Location VU University Medical Center, Amsterdam, The Netherlands (D.M.).
de Waard V; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, University of Amsterdam, Amsterdam UMC, Location Academic Medical Center, The Netherlands (C.Y., A.M., C.J.M.d.V., V.d.W.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Nov; Vol. 41 (11), pp. 2693-2707. Date of Electronic Publication: 2021 Sep 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cell Differentiation*
Cell Plasticity*
Atherosclerosis/*metabolism
Kruppel-Like Transcription Factors/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Cell Proliferation ; Humans ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Plaque, Atherosclerotic ; Signal Transduction
Czasopismo naukowe
Tytuł :
AMOTL2 restrains transforming growth factor-β1-induced proliferation and extracellular matrix deposition of airway smooth muscle cells via the down-regulation of YAP1 activation.
Autorzy :
Fang P; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
Deng WJ; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
Fan N; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
Shi J; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
Shi HY; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
Ou L; Special Hospital Ward, Xi'an Children's Hospital, Xi'an, China.
Pan JL; Respiratory Department, Xi'an Children's Hospital, Xi'an, China.
Yang SY; Division of Pulmonary and Critical Care Medicine, the Second Affiliated Hospital of Xi'an Jiaotong University, Xian, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2021 Nov; Vol. 36 (11), pp. 2225-2235. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article
MeSH Terms :
Extracellular Matrix*
Myocytes, Smooth Muscle*/cytology
Transforming Growth Factor beta1*/pharmacology
Carrier Proteins/*genetics
Adaptor Proteins, Signal Transducing/genetics ; Animals ; Cell Proliferation ; Cells, Cultured ; Down-Regulation ; Mice
Czasopismo naukowe
Tytuł :
Smooth Muscle Cell Molecular Underpinnings of Vascular Ageing.
Autorzy :
Regnault V; Université de Lorraine, INSERM, DCAC, Nancy, France.
Raoul A; Université de Lorraine, INSERM, DCAC, Nancy, France.
Schellenberg C; Université de Lorraine, INSERM, DCAC, Nancy, France.
Lacolley P; Université de Lorraine, INSERM, DCAC, Nancy, France. Electronic address: .
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Źródło :
Heart, lung & circulation [Heart Lung Circ] 2021 Nov; Vol. 30 (11), pp. 1595-1598.
Typ publikacji :
Editorial
MeSH Terms :
Myocytes, Smooth Muscle*
Vascular Stiffness*
Muscle, Smooth, Vascular
Opinia redakcyjna
Tytuł :
Ginger metabolites and metabolite-inspired synthetic products modulate intracellular calcium and relax airway smooth muscle.
Autorzy :
Luković E; Department of Anesthesiology, Columbia University, New York, New York.
Perez-Zoghbi JF; Department of Anesthesiology, Columbia University, New York, New York.
Zhang Y; Department of Anesthesiology, Columbia University, New York, New York.
Zhu Y; Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, Kannapolis, North Carolina.
Sang S; Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, Kannapolis, North Carolina.
Emala CW; Department of Anesthesiology, Columbia University, New York, New York.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Nov 01; Vol. 321 (5), pp. L912-L924. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Ginger*/metabolism
Calcium/*metabolism
Muscle Relaxation/*drug effects
Myocytes, Smooth Muscle/*drug effects
Animals ; Asthma/chemically induced ; Asthma/metabolism ; Bronchoconstriction/drug effects ; Cyclic Nucleotide Phosphodiesterases, Type 4/metabolism ; Humans ; Isoproterenol/pharmacology ; Lung/drug effects ; Lung/metabolism ; Mice, Inbred C57BL ; Muscle Relaxation/physiology ; Muscle, Smooth/metabolism ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Tytuł :
Myricetin suppresses the proliferation and migration of vascular smooth muscle cells and inhibits neointimal hyperplasia via suppressing TGFBR1 signaling pathways.
Autorzy :
Chen G; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Xu H; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Wu Y; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Han X; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Xie L; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Zhang G; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China.
Liu B; Department of Traditional Chinese Medicine (Institute of Integration of Traditional and Western Medicine of Guangzhou Medical University, State Key Laboratory of Respiratory Disease), the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Guangzhou 510260, China. Electronic address: .
Zhou Y; School of Traditional Chinese Medicine, Department of Traditional Chinese Medicine, Nanfang Hospital (ZengCheng Branch), Southern Medical University, Guangzhou 510515, China. Electronic address: .
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Źródło :
Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2021 Nov; Vol. 92, pp. 153719. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article
MeSH Terms :
Muscle, Smooth, Vascular*
Myocytes, Smooth Muscle*
Animals ; Cell Movement ; Cell Proliferation ; Cells, Cultured ; Flavonoids/pharmacology ; Hyperplasia ; Mice ; Molecular Docking Simulation ; Receptor, Transforming Growth Factor-beta Type I
Czasopismo naukowe
Tytuł :
Knockdown of NOVA1 inhibits inflammation and migration of asthmatic airway smooth muscle cells to regulate PTEN/Akt pathway by targeting PTBP1.
Autorzy :
Cheng Y; Department of Pediatrics, Weinan Maternal and Child Health Hospital, Weinan City, Shaanxi Province, 714000, China.
Wang N; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China.
Zhao L; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China.
Liu C; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China.
Wang J; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China.
Ma C; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China.
Shi X; Respiratory Asthma Center of Xi'an Children's Hospital, Xi'an City, Shaanxi Province, 710043, China. Electronic address: .
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Źródło :
Molecular immunology [Mol Immunol] 2021 Oct; Vol. 138, pp. 31-37. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article
MeSH Terms :
Asthma/*pathology
Heterogeneous-Nuclear Ribonucleoproteins/*metabolism
Myocytes, Smooth Muscle/*metabolism
Polypyrimidine Tract-Binding Protein/*metabolism
RNA-Binding Proteins/*metabolism
Signal Transduction/*physiology
Adolescent ; Airway Remodeling ; Asthma/metabolism ; Asthma/physiopathology ; Cell Movement/physiology ; Child ; Child, Preschool ; Female ; Gene Expression Regulation ; Gene Knockdown Techniques ; Humans ; Inflammation/metabolism ; Inflammation/pathology ; Male ; Myocytes, Smooth Muscle/pathology ; PTEN Phosphohydrolase/metabolism ; Proto-Oncogene Proteins c-akt/metabolism
Czasopismo naukowe
Tytuł :
Flow analysis of Carreau fluid model induced by the ciliary cells, smooth muscle cells and pressure gradient at the ampullar region entrance.
Autorzy :
Ashraf H; Department of Mathematics, University of Okara, Okara, Pakistan. .; Department of Mathematics and Statistics, Riphah International University Islamabad, Sector I-14, Islamabad, Pakistan. .
Siddiqui AM; Department of Mathematics, Pennsylvania State University, York Campus, York, PA, 17403, USA.
Rana MA; Department of Mathematics and Statistics, Riphah International University Islamabad, Sector I-14, Islamabad, Pakistan.
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Źródło :
Theory in biosciences = Theorie in den Biowissenschaften [Theory Biosci] 2021 Oct; Vol. 140 (3), pp. 249-263. Date of Electronic Publication: 2021 Jul 03.
Typ publikacji :
Journal Article
MeSH Terms :
Myocytes, Smooth Muscle*
Female ; Humans ; Motion
Czasopismo naukowe
Tytuł :
Transcervical Transtracheal Resection of Cervical Esophageal Smooth Muscle Tumor.
Autorzy :
Chow VLY; Department of Surgery, Division of Head and Neck Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong. Electronic address: .
Ho VWY; Department of Surgery, Division of Head and Neck Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Wong IYH; Department of Surgery, Division of Esophageal and Upper Gastrointestinal Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Chan FSY; Department of Surgery, Division of Esophageal and Upper Gastrointestinal Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Law SYK; Department of Surgery, Division of Esophageal and Upper Gastrointestinal Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Chan JYW; Department of Surgery, Division of Head and Neck Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
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Źródło :
The Annals of thoracic surgery [Ann Thorac Surg] 2021 Oct; Vol. 112 (4), pp. e299-e301. Date of Electronic Publication: 2021 Mar 06.
Typ publikacji :
Journal Article
MeSH Terms :
Esophageal Neoplasms/*surgery
Esophagectomy/*methods
Smooth Muscle Tumor/*surgery
Esophageal Neoplasms/diagnostic imaging ; Esophageal Neoplasms/pathology ; Humans ; Smooth Muscle Tumor/diagnostic imaging ; Smooth Muscle Tumor/pathology
Czasopismo naukowe
Tytuł :
SP1-mediated transcriptional activation of PTTG1 regulates the migration and phenotypic switching of aortic vascular smooth muscle cells in aortic dissection through MAPK signaling.
Autorzy :
Hu C; Department of Cardiology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515000, China.
Huang W; Department of Cardiac Surgery, First Affiliated Hospital of Shantou University Medical College, Shantou, 515000, China.
Xiong N; Shantou University Medical College, Shantou, 515000, China.
Liu X; Department of Neurology, First Affiliated Hospital of Shantou University Medical College, Shantou, 515000, China. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 30; Vol. 711, pp. 109007. Date of Electronic Publication: 2021 Aug 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aneurysm, Dissecting/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
Securin/*metabolism
Sp1 Transcription Factor/*metabolism
Aorta/metabolism ; Becaplermin/pharmacology ; Cell Movement/physiology ; Cell Proliferation/physiology ; Cells, Cultured ; Gene Knockdown Techniques ; Humans ; MAP Kinase Signaling System/physiology ; Middle Aged ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/drug effects ; Myocytes, Smooth Muscle/drug effects ; Securin/genetics ; Transcriptional Activation/physiology ; Up-Regulation/drug effects
Czasopismo naukowe
Tytuł :
Hybrids between H 2 S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells.
Autorzy :
Giordano F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Corvino A; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Scognamiglio A; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Citi V; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Gorica E; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Fattorusso C; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Persico M; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Caliendo G; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Fiorino F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Magli E; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Perissutti E; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Santagada V; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Severino B; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Pavese RC; Genetic S.p.A, Via Della Monica 26, Castel San Giorgio, SA, Italy.
Petti F; Genetic S.p.A, Via Della Monica 26, Castel San Giorgio, SA, Italy.
Martelli A; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Calderone V; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Frecentese F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113517. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Betamethasone Valerate/*pharmacology
Bronchi/*drug effects
Hydrogen Sulfide/*pharmacology
Mast Cells/*drug effects
Myocytes, Smooth Muscle/*drug effects
Triamcinolone Acetonide/*pharmacology
Betamethasone Valerate/chemistry ; Bronchi/metabolism ; Cells, Cultured ; Dose-Response Relationship, Drug ; Humans ; Hydrogen Sulfide/chemistry ; Mast Cells/metabolism ; Models, Molecular ; Molecular Structure ; Myocytes, Smooth Muscle/metabolism ; Structure-Activity Relationship ; Triamcinolone Acetonide/chemistry
Czasopismo naukowe
Tytuł :
Role of Vascular Smooth Muscle Cell Phenotype Switching in Arteriogenesis.
Autorzy :
Ashraf JV; College of Health & Life Sciences, Hamad Bin Khalifa University, Qatar Foundation, Doha 34110, Qatar.
Al Haj Zen A; College of Health & Life Sciences, Hamad Bin Khalifa University, Qatar Foundation, Doha 34110, Qatar.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Arteries/*physiology
Cell Proliferation/*physiology
Muscle, Smooth, Vascular/*cytology
Myocytes, Smooth Muscle/*physiology
Vascular Remodeling/*physiology
Animals ; Arterial Occlusive Diseases/genetics ; Arterial Occlusive Diseases/metabolism ; Arterial Occlusive Diseases/physiopathology ; Arteries/cytology ; Arteries/metabolism ; Cell Proliferation/genetics ; Collateral Circulation/genetics ; Collateral Circulation/physiology ; Gene Expression ; Humans ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/metabolism ; Phenotype ; Vascular Remodeling/genetics
Czasopismo naukowe
Tytuł :
Glutamine switches vascular smooth muscle cells to synthetic phenotype through inhibiting miR-143 expression and upregulating THY1 expression.
Autorzy :
Zhang CY; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China.
Hu YC; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China.
Zhang Y; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China.
Ma WD; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China.
Song YF; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China.
Quan XH; Department of Cardiovascular Medicine, Xi'an No.1 Hospital, 30 Fen Xiang, South Street, 710004 Xi'an, China.
Guo X; Department of Cardiovascular Medicine, Xi'an No.1 Hospital, 30 Fen Xiang, South Street, 710004 Xi'an, China.
Wang CX; Department of Cardiovascular Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, 157 Xi Wu Road, 710004 Xi'an, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jul 15; Vol. 277, pp. 119365. Date of Electronic Publication: 2021 Mar 16.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation*
Glutamine/*pharmacology
MicroRNAs/*genetics
Muscle, Smooth, Vascular/*cytology
Myocytes, Smooth Muscle/*cytology
Thy-1 Antigens/*metabolism
Cell Differentiation ; Cell Proliferation ; Cells, Cultured ; Humans ; MicroRNAs/antagonists & inhibitors ; Muscle, Smooth, Vascular/drug effects ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/drug effects ; Myocytes, Smooth Muscle/metabolism ; Phenotype ; Signal Transduction ; Thy-1 Antigens/genetics ; Wound Healing
Czasopismo naukowe
Tytuł :
Generation and Characterization of Human Mesenchymal Stem Cell-Derived Smooth Muscle Cells.
Autorzy :
Sivaraman S; Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Hedrick J; Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Ismail S; Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Slavin C; Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Rao RR; Department of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Sep 25; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 25.
Typ publikacji :
Journal Article
MeSH Terms :
Mesenchymal Stem Cells/*cytology
Myocytes, Smooth Muscle/*cytology
Adult ; Cell Differentiation/physiology ; Female ; Humans ; Male ; Mesenchymal Stem Cells/metabolism ; Middle Aged ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/metabolism ; Transforming Growth Factor beta1/metabolism ; Young Adult
Czasopismo naukowe
Tytuł :
MLKL and CaMKII Are Involved in RIPK3-Mediated Smooth Muscle Cell Necroptosis.
Autorzy :
Zhou T; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
DeRoo E; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Yang H; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Stranz A; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Wang Q; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
Ginnan R; Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Singer HA; Department of Molecular and Cellular Physiology, Albany Medical College, Albany, NY 12208, USA.
Liu B; Department of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Cellular and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.
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Źródło :
Cells [Cells] 2021 Sep 12; Vol. 10 (9). Date of Electronic Publication: 2021 Sep 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Necrosis*
Aortic Aneurysm, Abdominal/*pathology
Calcium-Calmodulin-Dependent Protein Kinase Type 2/*metabolism
Myocytes, Smooth Muscle/*pathology
Protein Kinases/*metabolism
Receptor-Interacting Protein Serine-Threonine Kinases/*physiology
Animals ; Aortic Aneurysm, Abdominal/chemically induced ; Aortic Aneurysm, Abdominal/metabolism ; Calcium Chloride/toxicity ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/antagonists & inhibitors ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myocytes, Smooth Muscle/metabolism ; Phosphorylation ; Protein Kinases/chemistry ; Protein Kinases/genetics ; RNA, Small Interfering/genetics ; Signal Transduction ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Tytuł :
Store-operated calcium entry-associated regulatory factor regulates airway inflammation and airway remodeling in asthma mice models.
Autorzy :
Wang YM; Department of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Xu WJ; Department of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Xiang LL; Department of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Ding M; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Zhang JJ; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Lu JY; Ministry of Education Key Laboratory of Environment and Health, Department of Epidemiology and Biostatics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xie BJ; Department of Respiratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
Gao YD; Department of Allergology, Zhongnan Hospital of Wuhan University, Wuhan, People's Republic of China.
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Źródło :
American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2021 Sep 01; Vol. 321 (3), pp. L533-L544. Date of Electronic Publication: 2021 Jul 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Airway Remodeling/*immunology
Asthma/*immunology
Calcium-Binding Proteins/*immunology
Gene Expression Regulation/*immunology
Lung/*immunology
Membrane Proteins/*immunology
Myocytes, Smooth Muscle/*immunology
Airway Remodeling/drug effects ; Airway Remodeling/genetics ; Airway Resistance/drug effects ; Airway Resistance/genetics ; Airway Resistance/immunology ; Animals ; Asthma/chemically induced ; Asthma/genetics ; Calcium-Binding Proteins/genetics ; Female ; Gene Expression Regulation/drug effects ; Humans ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/immunology ; Lung/pathology ; Membrane Proteins/genetics ; Mice ; Mice, Inbred BALB C ; Mice, Transgenic ; Myocytes, Smooth Muscle/pathology
Czasopismo naukowe
Tytuł :
Diabetes Impaired Ischemia-Induced PDGF (Platelet-Derived Growth Factor) Signaling Actions and Vessel Formation Through the Activation of Scr Homology 2-Containing Phosphatase-1.
Autorzy :
Mercier C; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Brazeau T; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Lamoureux J; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Boisvert E; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Robillard S; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Breton V; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Paré M; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Guay A; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Lizotte F; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.
Despatis MA; Department of Surgery (M.-A.D.), Université de Sherbrooke, Québec, Canada.
Geraldes P; Research Center of the Centre Hospitalier Universitaire de Sherbrooke (C.M., T.B., J.L., E.B., S.R., V.B., M.P., A.G., F.L., P.G.), Université de Sherbrooke, Québec, Canada.; Division of Endocrinology, Department of Medicine (P.G.), Université de Sherbrooke, Québec, Canada.
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. 2469-2482. Date of Electronic Publication: 2021 Jul 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Angiogenesis Inducing Agents/*pharmacology
Diabetes Mellitus, Experimental/*enzymology
Diabetic Angiopathies/*enzymology
Hindlimb/*blood supply
Ischemia/*enzymology
Muscle, Smooth, Vascular/*drug effects
Myocytes, Smooth Muscle/*drug effects
Neovascularization, Physiologic/*drug effects
Platelet-Derived Growth Factor/*pharmacology
Protein Tyrosine Phosphatase, Non-Receptor Type 6/*metabolism
Animals ; Blood Glucose/metabolism ; Case-Control Studies ; Cattle ; Cell Hypoxia ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Cells, Cultured ; Diabetes Mellitus, Experimental/genetics ; Diabetes Mellitus, Experimental/physiopathology ; Diabetic Angiopathies/genetics ; Diabetic Angiopathies/physiopathology ; Enzyme Activation ; Humans ; Ischemia/physiopathology ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/enzymology ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/enzymology ; Myocytes, Smooth Muscle/pathology ; Protein Tyrosine Phosphatase, Non-Receptor Type 6/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
A Smooth Muscle Cell-Enriched Long Noncoding RNA Regulates Cell Plasticity and Atherosclerosis by Interacting With Serum Response Factor.
Autorzy :
Ni H; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).; Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China (H.N., Q.D.).
Haemmig S; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Deng Y; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Chen J; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Simion V; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Yang D; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Sukhova G; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Shvartz E; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Wara AKMK; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Cheng HS; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Pérez-Cremades D; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Assa C; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Sausen G; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Zhuang R; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Dai Q; Department of Cardiology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, China (H.N., Q.D.).
Feinberg MW; Department of Medicine, Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA (H.N., S.H., Y.D., J.C., V.S., D.Y., G. Sukhova, E.S., A.K.M.K.W., H.S.C., D.P.-C., C.A., G. Sausen, R.Z., M.W.F.).
Pokaż więcej
Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Sep; Vol. 41 (9), pp. 2399-2416. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Plasticity*
Atherosclerosis/*metabolism
Muscle, Smooth, Vascular/*metabolism
Myocytes, Smooth Muscle/*metabolism
RNA, Long Noncoding/*metabolism
Serum Response Factor/*metabolism
Animals ; Atherosclerosis/genetics ; Atherosclerosis/pathology ; Cell Line ; Cell Movement ; Cell Proliferation ; Disease Models, Animal ; Humans ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Muscle, Smooth, Vascular/pathology ; Myocytes, Smooth Muscle/pathology ; Phenotype ; Plaque, Atherosclerotic ; RNA, Long Noncoding/genetics ; Receptors, LDL/deficiency ; Receptors, LDL/genetics ; Serum Response Factor/genetics ; Signal Transduction
Czasopismo naukowe

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